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Journal articles on the topic 'LDL/HDL'

Author: Grafiati

Published: 4 May 2024

Last updated: 31 July 2025

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1

Amrullah, Amran, Budi Handono, and Akhmad Yogi Pramatirta. "Rasio Low Density Lipoprotein dan High Density Lipoprotein pada Preeklamsi Berat dibandingkan dengan Kehamilan Normal di Rumah Sakit Dr. Hasan Sadikin Bandung." Indonesian Journal of Obstetrics & Gynecology Science 2, no. 1 (2019): 67. http://dx.doi.org/10.24198/obgynia.v2i1.79.

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AbstractObjective: This study aims to distinguish level of (LDL/HDL) and Low Density Lipoprotein/High Density Lipoprotein ratio in severe preeclampsia patient compared to normal pregnancy.Method: The study design was comparative cross-sectional study with consecutive sampling method that compared the laboratory results of LDL, HDL and ratio LDL/HDL that met the inclusion criteria. Subjects of this study were severe preeclampsia and normal pregnancy patient that fulfilled the inclusion criteria (n=60) in Dr. Hasan Sadikin General Hospital Bandung during August-September 2017.Result: It is revea

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Fujihara, Kazuya, Hiroaki Suzuki, Akira Sato, et al. "Circulating Malondialdehyde-Modified LDL-Related Variables and Coronary Artery Stenosis in Asymptomatic Patients with Type 2 Diabetes." Journal of Diabetes Research 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/507245.

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Aims. To elucidate the levels of malondialdehyde-modified LDL (MDA-LDL)-related variables for predicting coronary artery stenosis (CAS) by coronary CT angiography (CCTA) in asymptomatic patients with type 2 diabetes (T2DM).Methods. Enrolled were 36 Japanese patients with T2DM who underwent CCTA and in whom MDA-LDL levels were measured. Definition of CAS was luminal narrowing of ≥50%. Trends through tertiles of each MDA-LDL-related variable were analyzed with a general linear model. The ability of each MDA-LDL-related variable to predict CAS was compared to areas under the curve (AUCs) in recei

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J.-M.M. "LDL, oui, mais HDL?" Revue Francophone des Laboratoires 2007, no. 392 (2007): 15. http://dx.doi.org/10.1016/s1773-035x(06)80621-0.

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Baruch, Lawrence, Valerie J. Chiong, Sanjay Agarwal, and Bhanu Gupta. "Discordance of Non-HDL and Directly Measured LDL Cholesterol: Which Lipid Measure is Preferred When Calculated LDL Is Inaccurate?" Cholesterol 2013 (April 23, 2013): 1–6. http://dx.doi.org/10.1155/2013/502948.

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Objective. To determine if non-HDL cholesterol (N-HDL) and directly measured LDL cholesterol (D-LDL) are clinically equivalent measurements. Patients and Methods. Eighty-one subjects recruited for 2 cholesterol treatment studies had at least 1 complete fasting lipid panel and D-LDL performed simultaneously; 64 had a second assessment after 4 to 6 weeks, resulting in 145 triads of C-LDL, D-LDL, and N-HDL. To directly compare N-HDL to D-LDL and C-LDL, we normalized the N-HDL by subtracting 30 from the N-HDL (N-HDLA). Results. There was significant correlation between N-HDLA, D-LDL, and C-LDL. Co

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Dr, Aqsa Choudhary Dr Masooma Batool Dr Muntaha Munawar. "A DESCRIPTIVE RESEARCH TO ASSESS THE LIPID PROFILE AMONG PATIENTS DIAGNOSED WITH HYPERTENSION AT MAYO HOSPITAL, LAHORE." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 04 (2019): 8548–55. https://doi.org/10.5281/zenodo.2652822.

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<strong><em>Objective: </em></strong><em>The purpose of this study was to see the lipid profile in hypertension cases.</em> <strong><em>Methods: </em></strong><em>This descriptive study held at Mayo Hospital, Lahore from April 2017 to August 2018. A total of 100 patients admitted with hypertension were the participants of the study. The patients are in the range of 40-80 years. Both known hypertensive patients who were on treatment for a varying time and newly diagnosed hypertensive patients participated in the study.</em> <strong><em>Results: </em></strong><em>Serum TC, LDL/ HDL, VLDL, TGL, T

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Pian, M. S., and L. G. Dobbs. "Lipoprotein-stimulated surfactant secretion in alveolar type II cells: mediation by heterotrimeric G proteins." American Journal of Physiology-Lung Cellular and Molecular Physiology 273, no. 3 (1997): L634—L639. http://dx.doi.org/10.1152/ajplung.1997.273.3.l634.

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Low- and high-density lipoproteins (LDL and HDL, respectively) stimulate alveolar type II cells to secrete surfactant. Increases in phosphoinositide hydrolysis, cytosolic Ca2+, and membrane-associated protein kinase C activity precede LDL- and HDL-stimulated secretion. We report three lines of evidence supporting the hypothesis that Gi mediates LDL- and HDL-stimulated surfactant secretion and signal transduction in type II cells. First, pertussis toxin (PTX) inhibited secretion stimulated by the apolipoprotein ligands for either the LDL receptor or the HDL binding protein. Second, PTX inhibite

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Garcia-Rios, Antonio, Dragana Nikolic, Pablo Perez-Martinez, Jose Lopez-Miranda, Manfredi Rizzo, and Ron Hoogeveen. "LDL and HDL Subfractions, Dysfunctional HDL: Treatment Options." Current Pharmaceutical Design 20, no. 40 (2014): 6249–55. http://dx.doi.org/10.2174/1381612820666140620154014.

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Enomoto, Mika, Hisashi Adachi, Yuji Hirai, et al. "LDL-C/HDL-C Ratio Predicts Carotid Intima-Media Thickness Progression Better Than HDL-C or LDL-C Alone." Journal of Lipids 2011 (2011): 1–6. http://dx.doi.org/10.1155/2011/549137.

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High-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) are strong predictors of atherosclerosis. Statin-induced changes in the ratio of LDL-C to HDL-C (LDL-C/HDL-C) predicted atherosclerosis progression better than LDL-C or HDL-C alone. However, the best predictor of subclinical atherosclerosis remains unknown. Our objective was to investigate this issue by measuring changes in carotid intima-media thickness (IMT). A total of 1,920 subjects received health examinations in 1999, and were followed up in 2007. Changes in IMT (follow-up IMT/baselineIMT×100) we

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Syamsir, Syamsir, Liong Boy Kurniawan, Yuyun Widaningsih, Burhanuddin Bahar, Tenri Esa, and Andi Ariyandy. "Analysis of Reference Range Values of Lipid Profile and Lipid Ratio in Healthy Young Adult Population in Makassar, Indonesia." National Journal of Community Medicine 16, no. 06 (2025): 628–34. https://doi.org/10.55489/njcm.160620255002.

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Background: Lipids are essential for energy, hormones, digestion, and cell structure. A reference range of population-specific lipid profiles is essential due to variations. This study aimed to determine reference ranges for lipid profiles and ratios in healthy young adults in Makassar, Indonesia, and to identify specific differences by gender. Methods: We conducted a cross-sectional study of 120 healthy young adults (61 females, 59 males) aged 20-40 years. Lipid profiles (total cholesterol, LDL, HDL, triglycerides) and ratios (cholesterol/HDL, LDL/HDL, triglycerides/HDL) were measured using s

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Miida, Takashi, Yuichi Nakamura, Toru Mezaki, et al. "LDL-cholesterol and HDL-cholesterol concentrations decrease during the day." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 39, no. 3 (2002): 241–49. http://dx.doi.org/10.1258/0004563021901946.

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Background Homogenous assays for LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C) are highly accurate, with little interference from triglyceride. Using these methods, we measured postprandial LDL-C and HDL-C. Earlier studies suggested a postprandial decrease in LDL-C. Methods To elucidate whether LDL-C and HDL-C decrease significantly during the day, we determined daily profiles of LDL-C and HDL-C using homogeneous assays in subjects with normal coronary arteries (N; n = 10), and subjects with coronary artery disease (CAD; n = 23). Results In both groups, LDL-C and HDL-C were significantly

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Benitez, S., C. Bancells, J. Ordonez-Llanos, and J. L. Sanchez-Quesada. "HDL COUNTERACTS INFLAMMATORY PROPERTIES OF ELECTRONEGATIVE LDL (LDL(-))." Atherosclerosis Supplements 9, no. 1 (2008): 50. http://dx.doi.org/10.1016/s1567-5688(08)70195-8.

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Ohta, T., K. Saku, K. Takata, N. Nagata, KK Maung, and I. Matsuda. "Fractional esterification rate of cholesterol in high density lipoprotein (HDL) can predict the particle size of low density lipoprotein and HDL in patients with coronary heart disease." Atherosclerosis 135, no. 2 (1997): 205–12. https://doi.org/10.5281/zenodo.3374401.

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Fractional esterification rate of cholesterol in high density lipoprotein (HDL) (FER[HDL]) can predict the size distribution and physicochemical characteristics of HDL in plasma. In the present study, we investigated the correlation of FER(HDL) with the particle size of low density lipoprotein (LDL) (LDL-size) in 111 patients (81 males and 30 females) with coronary heart disease (CHD). The correlations of FER(HDL) and LDL-size with conventional lipid and lipoprotein parameters were also studied. FER(HDL) was closely associated with LDL-size (males: r = -0.618, females: r = -0.629, P < 0.001

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Giorgi Gogishvili, Giorgi Gogishvili, Shalva Petriashvili Shalva Petriashvili, Nino Nanobashvili Nino Nanobashvili, Nino Megrelishvili Nino Megrelishvili, and Iamze Taboridze Iamze Taboridze. "CHARACTERISTICS OF THE LIPID PROFIL YOUNG ADULTS WITH ISCHEMIC HEART DISEASE IN GEORGIAN POPULATION." PIRETC-Proceeding of The International Research Education & Training Centre 11, no. 01 (2021): 47–52. http://dx.doi.org/10.36962/1101202147.

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Objective: Impaired lipoprotein metabolism is a significant and modifiable risk factor for atherosclerotic cardiovascular disease. Aim: The aim of our study was to determine the diagnostic accuracy of lipid profile indices in young adults in Georgian population. Methods: Under our observation were 107 patients with ischemic heart disease, aged 18-45 years, From the St. John The Merciful Private Clinic contingent. Examination: anamnesis, cardiography, echocardiography, coronography, blood lipid metabolism. Total cholesterol (TC), high-density lipoprotein cholesterol (HDL), low-density lipoprote

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Mascarenhas-Melo, Filipa, José Sereno, Edite Teixeira-Lemos, et al. "Implication of Low HDL-c Levels in Patients with Average LDL-c Levels: A Focus on Oxidized LDL, Large HDL Subpopulation, and Adiponectin." Mediators of Inflammation 2013 (2013): 1–12. http://dx.doi.org/10.1155/2013/612038.

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To evaluate the impact of low levels of high density lipoprotein cholesterol (HDL-c) on patients with LDL-c average levels, focusing on oxidative, lipidic, and inflammatory profiles. Patients with cardiovascular risk factors (n=169) and control subjects (n=73) were divided into 2 subgroups, one of normal HDL-c and the other of low HDL-c levels. The following data was analyzed: BP, BMI, waist circumference and serum glucose Total-c, TGs, LDL-c, oxidized LDL, total HDL-c and subpopulations (small, intermediate, and large), paraoxonase-1 (PON1) activity, hsCRP, uric acid, TNF-α, adiponectin, VEGF

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Merdiana, Novita, and Hesti Murwani Rahayuningsih. "PENGARUH PEMBERIAN ESTER STANOL TERHADAP KADAR KOLESTEROL LDL DAN HDL WANITA DISLIPIDEMIA." Journal of Nutrition College 3, no. 1 (2014): 243–50. http://dx.doi.org/10.14710/jnc.v3i1.4603.

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Latar belakang : Dislipidemia merupakan salah satu faktor risiko terjadinya penyakit jantung dan pembuluh darah. Ester stanol merupakan pangan fungsional yang dapat menurunkan kadar kolesterol LDL dengan cara menghambat penyerapan kolesterol di usus halus dan mengaktifkan reseptor LDL di permukaan sel.Metode : Jenis penelitian ini adalah quasi experimental. Subyek wanita dislipidemia dengan kadar kolesterol LDL ≥ 130 mg/dl dan HDL < 50 mg/dl. Subyek dibagi menjadi 2 kelompok, yaitu kelompok perlakuan yang diberikan ester stanol 3,4 g dalam susu rendah lemak dan kelompok kontrol yang diberik

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Karádi, I., L. Romics, P. Kempler, I. Balogh, I. Szilvási, and L. Littmann. "HDL protection against atherogenic LDL?" Basic Research in Cardiology 82, no. 6 (1987): 596–97. http://dx.doi.org/10.1007/bf01907230.

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Aumiller, Jochen. "DEFINE: HDL verdoppelt, LDL halbiert." CardioVasc 10, no. 6 (2010): 16. http://dx.doi.org/10.1007/bf03358836.

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Nurhani, Mazdalina Rahmawandari, Kusworini, and Bambang Rahardjo. "Correlation between LDL, HDL, LDL/HDL Ratio and Preeclampsia incidence at RSUD Pamekasan, indonesia." Indian Journal of Public Health Research & Development 10, no. 9 (2019): 1139. http://dx.doi.org/10.5958/0976-5506.2019.02596.8.

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Kalahasthi, Ravibabu, Vinaykumar Adepu, Rakesh Balachandar, and Raju Nagaraju. "Association between non-high density lipoprotein-cholesterol fractions and presence of allostatic load among industrial workers." Indian Journal of Physiology and Pharmacology 66 (December 29, 2022): 268–75. http://dx.doi.org/10.25259/ijpp_164_2022.

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Objectives: Non-high density lipoprotein-cholesterol (non-HDL-C) fraction is the total cholesterol (TC) minus HDL-C. It is not a routinely reported component of lipid profile and is used in lipoprotein lowering therapy and prediction of coronary artery disease, target organ damage and atherosclerosis. Allostatic load (AL) is an imbalance between repetitive chronic exposure to stress and adaptive response. The present study investigates the association between non-HDL-C and its fractions (non-HDL-C/HDL-C, non-HDL-C/TC, non-HDL-C/ triglyceride [TG] and non-HDL-C/low-density lipoprotein-cholester

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García-Heredia, Anabel, Judit Marsillach, Anna Rull, et al. "Paraoxonase-1 Inhibits Oxidized Low-Density Lipoprotein-Induced Metabolic Alterations and Apoptosis in Endothelial Cells: A Nondirected Metabolomic Study." Mediators of Inflammation 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/156053.

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We studied the influence of PON1 on metabolic alterations induced by oxidized LDL when incubated with endothelial cells. HUVEC cells were incubated with native LDL, oxidized LDL, oxidized LDL plus HDL from wild type mice, and oxidized LDL plus HDL from PON1-deficient mice. Results showed alterations in carbohydrate and phospholipid metabolism and increased apoptosis in cells incubated with oxidized LDL. These changes were partially prevented by wild type mouse HDL, but the effects were less effective with HDL from PON1-deficient mice. Our results suggest that PON1 may play a significant role i

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Saputro, Zanuar Bagus, Tjitra Wardani, and Purwo Sri Rejeki. "The Effect of Moderate Intensity Fun Aerobic Gym on HDL-C and LDL- C on Overweight Women." Folia Medica Indonesiana 55, no. 2 (2021): 89. http://dx.doi.org/10.20473/fmi.v55i2.24511.

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Overweight and obesity is a major health problem in throughout the world. Hyperlipidemia and obesity are risk factor the occurrence of cardiovascular disease. Exercise is recommended as a therapeutic lifestyle changes because it leads to a variety of health benefits. Fun Aerobic gymnastics aerobics one which is quite popular in the community and a gym. Describe the gymnastics fun aerobic workout's effectiveness against related to prevention of cardiovascular disease with seeing the results before and after doing gymnastics with the result of increasing levels of HDL-c and LDL/HDL Ratios as wel

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Saputro, Zanuar Bagus, Tjitra Wardani, and Purwo Sri Rejeki. "The Effect of Moderate Intensity Fun Aerobic Gym on HDL-C and LDL- C on Overweight Women." Folia Medica Indonesiana 55, no. 2 (2019): 89. http://dx.doi.org/10.20473/fmi.v55i2.14331.

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Overweight and obesity is a major health problem in throughout the world. Hyperlipidemia and obesity are risk factor the occurrence of cardiovascular disease. Exercise is recommended as a therapeutic lifestyle changes because it leads to a variety of health benefits. Fun Aerobic gymnastics aerobics one which is quite popular in the community and a gym. Describe the gymnastics fun aerobic workout's effectiveness against related to prevention of cardiovascular disease with seeing the results before and after doing gymnastics with the result of increasing levels of HDL-c and LDL/HDL Ratios as wel

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Kurniawan, Liong Boy, Uleng Bahrun, and Darmawaty ER. "ANGKA BANDING LIPID DI INFARK MIOKARD." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 20, no. 1 (2016): 1. http://dx.doi.org/10.24293/ijcpml.v20i1.437.

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Lipid profiles are used as the regular tests which performed to predict and evaluate the risk of coronary heart disease. The routine lipid tests include total cholesterol, LDL, HDL and triglyceride level. The total cholesterol/HDL and LDL/HDL ratio are often used as predictors of coronary heart disease. This study was performed to know the lipid level and ratio by comparing the condition in myocardial infarction patients and young adult controls and to observe the percentage of their lipid level and ratio exceeding the recommended optimal value. A retrospective study was performed using second

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Larifla, Laurent, Valerie Bassien-Capsa, Fritz-Line Velayoudom, et al. "Influence of Common Gene Variants on Lipid Levels and Risk of Coronary Heart Disease in Afro-Caribbeans." International Journal of Molecular Sciences 25, no. 20 (2024): 11140. http://dx.doi.org/10.3390/ijms252011140.

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A lower mortality rate from coronary artery disease (CAD) and a more favourable lipid profile have been reported in Afro-Caribbeans compared with people of European ancestry. The aim of this study was to determine whether common lipid variants identified in other populations are associated with lipid levels and CAD in Afro-Caribbeans. We studied 705 Afro-Caribbeans (192 with CAD) who were genotyped for 13 lipid-associated variants. We calculated three polygenic risk scores (PRSs) for elevated LDL (LDL-PRS), decreased HDL (HDL-PRS), and elevated triglycerides (TG-PRS). LDL-PRS, HDL-PRS, and TG-

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LeCheminant, James D., Larry A. Tucker, Bruce W. Bailey, and Travis Peterson. "The Relationship Between Intensity of Physical Activity and HDL Cholesterol in 272 Women." Journal of Physical Activity and Health 2, no. 3 (2005): 333–44. http://dx.doi.org/10.1123/jpah.2.3.333.

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Purpose:To determine objectively measured intensity of physical activity (iPA) and its relationship to high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and the LDL/HDL ratio in women.Methods:Two hundred seventy-two women (40.1 y) wore CSA-MTI model 7164 accelerometers to index intensity and volume of physical activity for 7 d. Blood lipids were measured at a certified laboratory.Results:HDL-C was 52.1 ± 10.1, 52.2 ± 9.7, and 56.1 ± 11.1 mg/dL for the low, medium, and high intensity groups (P = 0.040), LDL-C differences were not significant (P = 0.23).

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Mascarenhas-Melo, Filipa, Filipe Palavra, Daniela Marado, et al. "Emergent Biomarkers of Residual Cardiovascular Risk in Patients with Low HDL-c and/or High Triglycerides and Average LDL-c Concentrations: Focus on HDL Subpopulations, Oxidized LDL, Adiponectin, and Uric Acid." Scientific World Journal 2013 (2013): 1–16. http://dx.doi.org/10.1155/2013/387849.

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This study intended to determine the impact of HDL-c and/or TGs levels on patients with average LDL-c concentration, focusing on lipidic, oxidative, inflammatory, and angiogenic profiles. Patients with cardiovascular risk factors (n=169) were divided into 4 subgroups, combining normal and low HDL-c with normal and high TGs patients. The following data was analyzed: BP, BMI, waist circumference and serum glucose, Total-c, TGs, LDL-c, oxidized-LDL, total HDL-c and HDL subpopulations, paraoxonase-1 (PON1) activity, hsCRP, uric acid, TNF-α, adiponectin, VEGF, and iCAM1. The two populations with in

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Liu, Kan-Zhi, R. Anthony Shaw, Angela Man, Thomas C. Dembinski, and Henry H. Mantsch. "Reagent-free, Simultaneous Determination of Serum Cholesterol in HDL and LDL by Infrared Spectroscopy." Clinical Chemistry 48, no. 3 (2002): 499–506. http://dx.doi.org/10.1093/clinchem/48.3.499.

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Abstract Background: The purpose of this study was to assess the feasibility of infrared (IR) spectroscopy for the simultaneous quantification of serum LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C) concentrations. Methods: Serum samples (n = 90) were obtained. Duplicate aliquots (5 μL) of the serum specimens were dried onto IR-transparent barium fluoride substrates, and transmission IR spectra were measured for the dry films. In parallel, the HDL-C and LDL-C concentrations were determined separately for each specimen by standard methods (the Friedewald formula for LDL-C and an automated

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Feng, Yingmei. "LDL and HDL Counteract Hematopoietic Stem/Progenitor Cells in Regulation of Inflammation and Atherosclerosis." Blood 118, no. 21 (2011): 1288. http://dx.doi.org/10.1182/blood.v118.21.1288.1288.

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Abstract Abstract 1288 Low-density lipoprotein (LDL) is an independent risk factor in cardiovascular disease. Hypercholesterolemia-associated monocytosis and transformation of monocytes into macrophages are the main features underlying the proatherogenic property of LDL. Different from LDL, high-density lipoprotein (HDL) and its major apolipoprotein, apoA-I, counteract atherosclerosis by reversing cholesterol transport, inhibiting inflammatory cell adhesion to plaques, maintaining endothelial integrity, inhibiting oxidation, and as has recently been shown, suppressing hematopoietic stem cell (

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Nadhira, Aulia Ninggar, Ida Nurwati, and Dyah Ratna Budiani. "Efek Ekstrak Etanolik Daun Kelor Terhadap Kadar HDL, Kadar LDL, serta Ketebalan Aorta Tikus Wistar Model Sindrom Metabolik." Plexus Medical Journal 2, no. 1 (2023): 1–8. http://dx.doi.org/10.20961/plexus.v2i1.219.

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Pendahuluan: Daun kelor diketahui memiliki potensi menurunkan gejala sindrom metabolik. Kriteria sindrom metabolik antara lain yait terdapat penurunan HDL, peningkatan LDL, dan penebalan dinding aorta. Tujuan penelitian ini adalah mengetahui pengaruh pemberian ekstrak etanolik daun kelor terhadap kadar HDL, kadar LDL, dan ketebalan aorta tikus wistar jantan model sindrom metabolik. Metode: Penelitian bersifat eksperimental laboratorik menggunakan lima kelompok, yaitu KKN diberi pakan standar; KKP, KP1, KP2, dan KP3 diberi pakan tinggi lemak selama 28 hari dan injeksi STZ-NA pada hari ke-25. Ke

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Sarjana, Guruh, and Deny Yudi Fitranti. "PENGARUH PEMBERIAN JUS KULIT DELIMA MERAH (Punica granatum) TERHADAP KADAR LDL DAN HDL WANITA DISLIPIDEMIA." Journal of Nutrition College 3, no. 4 (2014): 538–46. http://dx.doi.org/10.14710/jnc.v3i4.6848.

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Latar Belakang : Dislipidemia merupakan salah satu faktor risiko terjadinya penyakit jantung dan pembuluh darah. Kulit delima mengandung anthocyanin yang dapat meningkatkan kadar HDL dan menurunkan kadar LDL. Penelitian ini bertujuan untuk mengetahui perbedaan kadar LDL dan HDL wanita usia 30-49 tahun yang diberi dan tidak diberi jus kulit delima (Punica granatum). Metode : Penelitian ini merupakan penelitian quasi experimental dengan rancangan pre-post control group design. Subjek adalah wanita dislipidemia dengan kadar kolesterol LDL > 130 mg/dl dan kadar kolesterol HDL < 40 mg/dl, Kel

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., Adi Priyana. "PETANDA KEBAHAYAAN (RISIKO) PENYAKIT JANTUNG KORONER TERKAIT LDL." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 14, no. 3 (2018): 102. http://dx.doi.org/10.24293/ijcpml.v14i3.931.

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Atherosclerosis is the most common cause of coronary heart disease (CHD), and it is still the primary cause of death in Indonesia and most industrialized countries. The conventional risk factor for atherosclerosis and CHD are diabetes mellitus, hypertension, dyslipidemiaand smoking. On the other hand, Lp (a), homocystein and small dense LDL (sd-LDL) have been considered as novel risk factors for CHDLow of high density lipoprotein (HDL), high of low density cholesterol (LDL-c) and high homocystein as part of dyslipidemia, has beenconsidered as independent risk factor for CHD.The principal objec

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Mackness, M. I., C. Abbott, S. Arrol, and P. N. Durrington. "The role of high-density lipoprotein and lipid-soluble antioxidant vitamins in inhibiting low-density lipoprotein oxidation." Biochemical Journal 294, no. 3 (1993): 829–34. http://dx.doi.org/10.1042/bj2940829.

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1. The oxidation of low-density lipoprotein (LDL) is believed to play a central role in atherogenesis. We have compared the effect of antioxidant vitamins and high-density lipoprotein (HDL) on the Cu(2+)-catalysed oxidation of LDL. 2. Antioxidant vitamin supplementation significantly reduced conjugated diene formation but did not affect the formation of lipid peroxides. 3. Conversely, HDL did not affect conjugated diene formation but inhibited the formation of lipid peroxides by up to 90%. 4. The inhibition by HDL of lipid peroxide formation in oxidized LDL was dependent on the concentration o

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Aulia, Daradjatul, Sri Rahayu Lestari, and Yunita Rakhmawati. "Complementary Food to Improving HDL & LDL in Malnourished Male Wistar Strain White Rats." BIO Web of Conferences 117 (2024): 01012. http://dx.doi.org/10.1051/bioconf/202411701012.

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Protein-energy malnutrition (PEM) causes a decrease in amino acid synthesis, which affects the decrease in High-Density Lipoprotein (HDL) levels and an increase in Low-Density Lipoprotein (LDL) levels. Improving HDL and LDL levels in malnourished can be managed by providing Complementary Food (CF) with main ingredients such as banana flour, cassava flour, and corn flour. This study aims to describe the effect of CF supplementation on the HDL and LDL levels of malnourished male Wistar rats. The research method was experimental with a Randomized Block Design using twenty-four male rats. The expe

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Li, Yufeng, Gang Li, Jari A. Laukkanen, Linping Wei, and Xinrui Chen. "Higher LDL-C/HDL-C Ratio Is Associated with Elevated HbA1c and Decreased eGFR Levels and Cardiac Remodeling in Elderly with Hypercholesterolemia." Journal of Cardiovascular Development and Disease 11, no. 5 (2024): 140. http://dx.doi.org/10.3390/jcdd11050140.

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This study aims to explore the relationship of the low-density lipoprotein cholesterol (LDL-C)/high-density lipoprotein (HDL-C) ratio with glycated hemoglobin (HbA1c), renal dysfunction, coronary heart disease (CHD) and cardiac structure and function in elderly patients with hypercholesterolemia. Methods: A total of 1129 hospitalized Chinese elderly (aged ≥ 65 years) with hypercholesterolemia were collected retrospectively. The patients were divided into low (<2.63), moderate (≥2.63 to <3.33) and high (≥3.33) LDL-C/HDL-C ratio groups according to the tertiles of LDL-C/HDL-C. Results: Reg

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Ciplak, Sibel, Ahmet Adiguzel, Yusuf Ziya Deniz, Melike Aba, and Unal Ozturk. "The Role of the Low-Density Lipoprotein/High-Density Lipoprotein Cholesterol Ratio as an Atherogenic Risk Factor in Young Adults with Ischemic Stroke: A Case—Control Study." Brain Sciences 13, no. 8 (2023): 1180. http://dx.doi.org/10.3390/brainsci13081180.

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Dyslipidemia is a major atherogenic risk factor for ischemic stroke. Stroke patients tend to have high levels of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and low levels of high-density lipoprotein cholesterol (HDL-C). Therefore, it is noteworthy that there has been an increase in ischemic stroke cases in young and elderly individuals in recent years. This study investigated the TC/HDL-C ratio and the LDL-C/HDL-C ratio, which may be more specific and common lipid parameters in young patients with ischemic stroke. This study aimed to demonstrate the sensitivity and

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Shawa, Hassan, Ferhat Deniz, Hadil Bazerbashi, et al. "Mitotane-Induced Hyperlipidemia: A Retrospective Cohort Study." International Journal of Endocrinology 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/624962.

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Limited data are available about mitotane-nduced hyperlipidemia. We retrospectively analyzed lipid data in 38 patients with adrenocortical carcinoma (ACC) who received mitotane therapy with emphasis on HDL cholesterol (HDL-c) and clinical predictors of lipid changes. At baseline, the mean levels of HDL-c, LDL-c, and triglycerides were 53.3 mg/dL, 114.4 mg/dL, and 149 mg/dL, respectively. HDL-c, LDL-c, and triglyceride concentrations significantly increased with mitotane therapy to a mean HDL peak (HDL-P) of 86.3 mg/dL (P<0.001), a mean LDL peak of 160.1 mg/dL (P<0.001), and a mean trigly

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Langlois, Michel R., M. John Chapman, Christa Cobbaert, et al. "Quantifying Atherogenic Lipoproteins: Current and Future Challenges in the Era of Personalized Medicine and Very Low Concentrations of LDL Cholesterol. A Consensus Statement from EAS and EFLM." Clinical Chemistry 64, no. 7 (2018): 1006–33. http://dx.doi.org/10.1373/clinchem.2018.287037.

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Abstract BACKGROUND The European Atherosclerosis Society–European Federation of Clinical Chemistry and Laboratory Medicine Consensus Panel aims to provide recommendations to optimize atherogenic lipoprotein quantification for cardiovascular risk management. CONTENT We critically examined LDL cholesterol, non-HDL cholesterol, apolipoprotein B (apoB), and LDL particle number assays based on key criteria for medical application of biomarkers. (a) Analytical performance: Discordant LDL cholesterol quantification occurs when LDL cholesterol is measured or calculated with different assays, especiall

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Aoua, Hanene, Ymène Nkaies, Ali Ben Khalfallah, Mohsen Sakly, Ezzedine Aouani, and Nebil Attia. "Association between Small Dense Low-Density Lipoproteins and High-Density Phospolipid Content in Patients with Coronary Artery Disease with or without Diabetes." Laboratory Medicine 51, no. 3 (2019): 271–78. http://dx.doi.org/10.1093/labmed/lmz067.

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Abstract Objective To evaluate the phospholipid profile in total plasma, non–high-density lipoprotein (HDL), and HDL fractions. We tried to correlate the phospholipid profile to low-density lipoprotein (LDL) size, as reflected by cholesterol content in each LDL subclass. Methods We measured small dense LDL-C levels after heparin-magnesium precipitation and measured high-density lipoprotein phospholipid (HDL-P) levels using a colorimetric enzymatic method. Results The correlation of the phospholipid profile to small dense LDL-C (sdLDL-C) in patients with coronary problems showed a negative asso

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Wang, Yanan, Chenchen Wei, Quhong Song, et al. "Reduction in the Ratio of Low-density Lipoprotein Cholesterol to Highdensity Lipoprotein Cholesterol is Associated with Increased Risks of Hemorrhagic Transformation in Patients with Acute Ischemic Stroke." Current Neurovascular Research 16, no. 3 (2019): 266–72. http://dx.doi.org/10.2174/1567202616666190619151914.

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Background and Purpose: Hemorrhagic transformation (HT) is a potentially serious complication in patients with acute ischemic stroke (AIS). Whether the ratio of low-density lipoprotein cholesterol to high-density lipoprotein cholesterol (LDL-C/HDL-C) is associated with HT remains unclear. Methods: Ischemic stroke patients within 7 days of stroke onset from January 2016 to November 2017 were included in this study. Lipid profiles were measured within 24h after admission. HT was determined by a second computed tomography or magnetic resonance imaging within 7 days after admission. Univariate and

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Kartikasari, Nur Indah, and Ahmad Syauqy. "PERBEDAAN KADAR KOLESTEROL LDL DAN HDL SEBELUM DAN SESUDAH PEMBERIAN JUS KACANG HIJAU (Phaseolus radiatus Linn) PADA PRIA DISLIPIDEMIA." Journal of Nutrition College 3, no. 4 (2014): 698–705. http://dx.doi.org/10.14710/jnc.v3i4.6870.

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Latar belakang : Dislipidemia merupakan salah satu faktor risiko dari penyakit kardiovaskuler. Kacang hijau mengandung isoflavon, protein, dan serat yang diketahui dapat menurunkan kadar kolesterol LDL dan meningkatkan kolesterol HDL. Tujuan : Mengetahui perbedaan kadar kolesterol LDL dan HDL sebelum dan sesudah pemberian jus kacang hijau.Metode : Penelitian ini merupakan pretest - post test with control group design. Subjek adalah 28 pria dengan kadar kolesterol LDL 130-189 mg/dl dan kadar kolesterol HDL <60 mg/dl. Kelompok perlakuan mendapatkan jus kacang hijau 400 ml dan kelompok kontrol

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Mascarenhas-Melo, Filipa, José Sereno, Edite Teixeira-Lemos, et al. "Markers of Increased Cardiovascular Risk in Postmenopausal Women: Focus on Oxidized-LDL and HDL Subpopulations." Disease Markers 35 (2013): 85–96. http://dx.doi.org/10.1155/2013/724706.

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Objective. To evaluate the effect of gender and menopause in cardiovascular risk (CVR) in a healthy population based on both classical and nontraditional markers.Methods. 56 men and 68 women (48 pre- and 20 postmenopause) were enrolled in the study. The following markers were analyzed: blood pressure (BP), body mass index (BMI), waist circumference (WC), glucose, total cholesterol (total-c), triglycerides (TGs), low-density lipoprotein cholesterol (LDL-c), oxidized-LDL (Ox-LDL), HDL-c and subpopulations, paraoxonase-1 activity, hsCRP, uric acid, tumor necrosis factor alpha (TNF-α), adiponectin

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Stokic, Edita, and Jela Marinkov. "Treatment of low HDL-cholesterol levels in the reduction of cardiovascular risk." Medical review 60, no. 3-4 (2007): 145–50. http://dx.doi.org/10.2298/mpns0704145s.

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Introduction. Although reduction of LDL-C levels is a priority in the treatment of dyslipidemia, not all coronary events are prevented despite aggressive LDL-C lowering, and risk reduction can be improved by treating additional lipid abnormalities. The Framingham Study was the first to demonstrate the inverse relationship between HDL-C and risk of coronary heart disease (CHD). This relationship was present at all levels of LDL-C, whereas the highest risk was associated with low HDL-C and high LDL-C. The antiatherogenic actions of HDL-cholesterol. The antiatherogenic actions of HDL-C are comple

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Rütti, Sabine, Jan A. Ehses, Rahel A. Sibler та ін. "Low- and High-Density Lipoproteins Modulate Function, Apoptosis, and Proliferation of Primary Human and Murine Pancreatic β-Cells". Endocrinology 150, № 10 (2009): 4521–30. http://dx.doi.org/10.1210/en.2009-0252.

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Abstract A low high-density lipoprotein (HDL) plasma concentration and the abundance of small dense low-density lipoproteins (LDL) are risk factors for developing type 2 diabetes. We therefore investigated whether HDL and LDL play a role in the regulation of pancreatic islet cell apoptosis, proliferation, and secretory function. Isolated mouse and human islets were exposed to plasma lipoproteins of healthy human donors. In murine and human β-cells, LDL decreased both proliferation and maximal glucose-stimulated insulin secretion. The comparative analysis of β-cells from wild-type and LDL recep

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Damirin, Alatangaole, Hideaki Tomura, Mayumi Komachi, et al. "Role of lipoprotein-associated lysophospholipids in migratory activity of coronary artery smooth muscle cells." American Journal of Physiology-Heart and Circulatory Physiology 292, no. 5 (2007): H2513—H2522. http://dx.doi.org/10.1152/ajpheart.00865.2006.

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The migration of vascular smooth muscle cells (SMCs) is a hallmark of the pathogenesis of atherosclerosis and restenosis after angioplasty. Plasma low-density lipoprotein (LDL), but not high-density lipoprotein (HDL), induced the migration of human coronary artery SMCs (CASMCs). Among bioactive lipids postulated to be present in LDL, lysophosphatidic acid (LPA) appreciably mimicked the LDL action. In fact, the LDL-induced migration was markedly inhibited by pertussis toxin, an LPA receptor antagonist Ki-16425, and a small interfering RNA (siRNA) targeted for LPA1 receptors. Moreover, LDL conta

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Laksana, Iqbal, Purwo Sri Rejeki, Lilik Herawati, Mohammad Anam Al Arif, and Indrayuni Lukitra Wardhani. "High-Fat Diet Increases Serum HDL, but Not for LDL and HDL/LDL Ratio in MICE." Folia Medica Indonesiana 57, no. 2 (2021): 117. http://dx.doi.org/10.20473/fmi.v57i2.16123.

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The use of a ketogenic diet with an increased proportion of fat is rampant lately, both as a therapy or even lifestyle. The use of a ketogenic diet is feared to cause dyslipidemia. It will also lead to atherosclerosis and thrombosis. This study aimed to determine the effect of a high-fat diet on HDL, LDL, and HDL/LDL ratio in mice. Thirty male Mus Musculus, 2-3 mo, 15-25 g divided into five groups diet. K1 (12% fat, 20% protein, 62% carb), K2 (30% fat, 60%protein), K3 (45% fat, 45% protein), K4 (60% fat, 30% protein) and K5 (75% fat, 15% protein) for 4 weeks. Feed and water by adlibitum. Blood

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Ikhsan, Mohd, and Tatik Mulyati. "PENGARUH PEMBERIAN NATA DE COCO TERHADAP KADAR KOLESTEROL LDL DAN HDL PADA WANITA DISLIPIDEMIA." Journal of Nutrition College 2, no. 2 (2013): 242–49. http://dx.doi.org/10.14710/jnc.v2i2.2749.

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Latar Belakang : Kadar kolesterol LDL yang tinggi dan HDL yang rendah berkaitan dengan penyebab utama terjadinya penyakit jantung dan pembuluh darah. Serat diketahui dapat menurunkan kadar kolesterol LDL serta meningkatkan kolesterol HDL. Nata de coco mengandung selulosa, hemiselulosa dan lignin yang memiliki efek hipokolesterolemia dalam darah.Metode : Jenis penelitian adalah true experimental dengan rancangan control group pre-test-post-test. Sebanyak 52 wanita dengan kadar kolesterol LDL ≥100 mg/dl dan HDL ≤50 mg/dl menjadi subyek dalam penelitian ini. Subyek dibagi menjadi 3 kelompok, yait

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Adegoke, Adeolu, Tatiana Yuzyuk, and Heather Nelson. "NMR Insights into Lipoprotein Particles: analyzing correlations with traditional lipid measurements." American Journal of Clinical Pathology 162, Supplement_1 (2024): S179—S180. http://dx.doi.org/10.1093/ajcp/aqae129.394.

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Abstract Introduction Lipid metabolism plays a crucial role in various physiological processes. Lipid molecules are transported by lipoproteins, and the intricate involvement of lipoproteins in cardiovascular disease (CVD) is well-established, given their diverse size, density, and lipid composition. The emergence of Nuclear Magnetic Resonance (NMR) spectroscopy, a high-resolution analytical technique, promotes the assessment of lipoprotein particle numbers and sizes. Studies suggest that the measurement of total low-density lipoprotein particle numbers (LDL-P), small LDL-P (SLDL-P), and total

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Ben Tekaya, A., E. Hannech, A. Fendri, et al. "AB0848 ATHEROGENIC INDEX IS THE BEST DETERMINANT OF SUBCLINICAL ATHEROSCLEROSIS IN SPONDYLOARTHRITIS PATIENTS." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1549.2–1549. http://dx.doi.org/10.1136/annrheumdis-2022-eular.3840.

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BackgroundBlood lipid levels particularly total cholesterol (CT), low-density lipoprotein cholesterol (C-LDL), high-density lipoprotein cholesterol (C-HDL), and triglycerides (TG), are commonly used to predict cardiovascular risk. However, it has been demonstrated that atherogenic index (CT/HDL, C-LDL/C-HDL) are prognostic indicators of atherosclerosis [1].ObjectivesThe purpose of our study was to determine the role of lipid indicators in predicting subclinical atherosclerosis among SpA patients.MethodsIt was a cross sectional study over a period of 12 months including patients with establishe

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Adam, Leonie, and Thomas Bobbert. "Non-HDL-Cholesterin." Diabetes aktuell 18, no. 06 (2020): 242–46. http://dx.doi.org/10.1055/a-1237-6894.

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ZUSAMMENFASSUNGDie diabetische Stoffwechsellage korreliert häufig mit einer Dyslipidämie, die sich typischerweise durch erhöhte Triglyzeride, niedriges HDL-Cholesterin und eine hohe Konzentration an small dense LDL-Cholesterin (LDL: low-density lipoprotein) auszeichnet. Zur kardiovaskulären Risikostratifizierung bei Diabetes mellitus Typ 2 eignet sich die Verwendung von Non-HDL-Cholesterin (HDL: high-density lipoprotein), um sämtliche potenziell atherogene Lipoproteine – VLDL (very-low-density lipoprotein), IDL (intermediate-density lipoprotein), LDL, Lipoprotein(a), Chylomikronen, Remnants –

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Patricia, Venny, Nining Kurniati, Citra Trisna, and Nana Munawar. "Description of The Risk Level of Heart Disease to The Ratio of LDL/HDL Patients at Rsud Dr. Adjidarmo." Journal of Noncommunicable Diseases Prevention and Control 1, no. 1 (2023): 8–12. http://dx.doi.org/10.61843/jondpac.v1i1.497.

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The increased risk of stroke is associated with high low-density lipoprotein (LDL) cholesterol, low high-density lipoprotein (HDL) cholesterol, and a high ratio of LDL and HDL cholesterol, and will be amplified if other stroke risk factors are present. The purpose of this study was to determine the ratio of LDL and HDL cholesterol in patients at RSUD Dr. Adjidarmo. The research design is descriptive research. With a total population of 150 people, a sample of 20% of the population, namely 30 people, was taken. The data collection technique in this study was primary data, namely through the med

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