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1

Golebiowski, Adam, Sean R. Klopfenstein, and David E. Portlock. "Lead compounds discovered from libraries." Current Opinion in Chemical Biology 5, no. 3 (June 2001): 273–84. http://dx.doi.org/10.1016/s1367-5931(00)00203-9.

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2

Zelikoff, J. T., J. H. Li, A. Hartwig, X. W. Wang, M. Costa, and T. G. Rossman. "Genetic toxicology of lead compounds." Carcinogenesis 9, no. 10 (1988): 1727–32. http://dx.doi.org/10.1093/carcin/9.10.1727.

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3

Wang, Yin, Yanjiao Xie, Wenlu Li, Zimeng Wang, and Daniel E. Giammar. "Formation of Lead(IV) Oxides from Lead(II) Compounds." Environmental Science & Technology 44, no. 23 (December 2010): 8950–56. http://dx.doi.org/10.1021/es102318z.

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4

Putra, Masteria Yunovilsa, and Tutik Murniasih. "Marine soft corals as source of lead compounds for anti-inflammatories." Journal of Coastal Life Medicine 4, no. 1 (January 2016): 73–77. http://dx.doi.org/10.12980/jclm.4.2016j5-226.

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5

Bläsing, Marc, Maria Benito Abascal, Yoshihiko Ninomiya, and Michael Müller. "Partitioning of Lead and Lead Compounds under Gasification-Like Conditions." Energy & Fuels 32, no. 1 (January 2, 2018): 651–57. http://dx.doi.org/10.1021/acs.energyfuels.7b02803.

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6

Masood, M. Abid, Marc Bazin, Mark E. Bunnage, Andrew Calabrese, Mark Cox, Sally-Ann Fancy, Elizabeth Farrant, et al. "Lead Diversification 2: Application to P38, gMTP and lead compounds." Bioorganic & Medicinal Chemistry Letters 22, no. 2 (January 2012): 1255–62. http://dx.doi.org/10.1016/j.bmcl.2011.11.033.

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7

Dahiya, Vinesh, Neeru Vasudeva, Sunil Sharma, Ashok Kumar, and David Rowley. "Lead Anti-Obesity Compounds from Nature." Endocrine, Metabolic & Immune Disorders - Drug Targets 20, no. 10 (December 2, 2020): 1637–53. http://dx.doi.org/10.2174/1871530320666200504092012.

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Background : Obesity has become a global issue, leading to increased risk of metabolic syndrome, which encompasses diabetes, cardiovascular disease, stroke, hypertension, and certain cancers. However, obesity is difficult to control through diet and exercise alone, as they are difficult to implement. Objective: The objective of this review is to elucidate the active constituents that can be obtained from various natural sources that act as anti-obesity agents. Due to the global rise in the prevalence of obesity, an urgent need to prevent and control it has arisen. Methods: For this review, we compiled information about natural anti-obesity products through an electronic search of the articles available via PubMed, Scopus, and other internet sources for the period 1975-2019 and included our own research. We analyzed and organized data on various natural products in popular use in addition to relevant pharmacognostic and biological studies. The products’ mechanisms of action were also investigated. Conclusion: Consumption of diets that include high amounts of active anti-obesity natural compounds is a promising strategy for the suppression of lipid accumulation and adipogenesis in obese individuals.
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8

Ancheeva, Elena, Georgios Daletos, and Peter Proksch. "Lead Compounds from Mangrove-Associated Microorganisms." Marine Drugs 16, no. 9 (September 7, 2018): 319. http://dx.doi.org/10.3390/md16090319.

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The mangrove ecosystem is considered as an attractive biodiversity hotspot that is intensively studied in the hope of discovering new useful chemical scaffolds, including those with potential medicinal application. In the past two decades, mangrove-derived microorganisms, along with mangrove plants, proved to be rich sources of bioactive secondary metabolites as exemplified by the constant rise in the number of publications, which suggests the great potential of this important ecological niche. The present review summarizes selected examples of bioactive compounds either from mangrove endophytes or from soil-derived mangrove fungi and bacteria, covering the literature from 2014 to March 2018. Accordingly, 163 natural products are described in this review, possessing a wide range of potent bioactivities, such as cytotoxic, antibacterial, antifungal, α-glucosidase inhibitory, protein tyrosine phosphatase B inhibitory, and antiviral activities, among others.
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9

Sagar, Sunil, Mandeep Kaur, and Kenneth P. Minneman. "Antiviral Lead Compounds from Marine Sponges." Marine Drugs 8, no. 10 (October 11, 2010): 2619–38. http://dx.doi.org/10.3390/md8102619.

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10

Bu, Ming, Burton B. Yang, and Liming Hu. "Natural Endoperoxides as Drug Lead Compounds." Current Medicinal Chemistry 23, no. 4 (February 4, 2016): 383–405. http://dx.doi.org/10.2174/0929867323666151127200949.

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11

Apers, S., A. Vlietinck, and L. Pieters. "Lignans and neolignans as lead compounds." Phytochemistry Reviews 2, no. 3 (January 2003): 201–17. http://dx.doi.org/10.1023/b:phyt.0000045497.90158.d2.

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12

Fattorusso, Ernesto, and Orazio Taglialatela-Scafati. "Marine endoperoxides as antimalarial lead compounds." Phytochemistry Reviews 9, no. 4 (September 18, 2010): 515–24. http://dx.doi.org/10.1007/s11101-010-9197-6.

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13

Stauber, J. L., T. M. Florence, B. L. Gulson, and L. S. Dale. "Percutaneous absorption of inorganic lead compounds." Science of The Total Environment 145, no. 1-2 (May 1994): 55–70. http://dx.doi.org/10.1016/0048-9697(94)90297-6.

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14

Roy, Nirmal K., and Toby G. Rossman. "Mutagenesis and comutagenesis by lead compounds." Mutation Research/Genetic Toxicology 298, no. 2 (December 1992): 97–103. http://dx.doi.org/10.1016/0165-1218(92)90034-w.

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15

Otoguro, Kazuhiko, Masato Iwatsuki, Aki Ishiyama, Miyuki Namatame, Aki Nishihara-Tukashima, Seiji Shibahara, Shinichi Kondo, Haruki Yamada, and Satoshi Ōmura. "Promising lead compounds for novel antiprotozoals." Journal of Antibiotics 63, no. 7 (May 26, 2010): 381–84. http://dx.doi.org/10.1038/ja.2010.50.

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16

Richard, Julian V., and Karl A. Werbovetz. "New antileishmanial candidates and lead compounds." Current Opinion in Chemical Biology 14, no. 4 (August 2010): 447–55. http://dx.doi.org/10.1016/j.cbpa.2010.03.023.

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17

Sun, Chee-Ching, Ten-Tsao Wong, Yaw-Huei Hwang, Kun-Yu Chao, Shiou-Hwa Jee, and Jung-Der Wang. "Percutaneous Absorption of Inorganic Lead Compounds." AIHA Journal 63, no. 5 (September 2002): 641–46. http://dx.doi.org/10.1080/15428110208984751.

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18

Hewitt, C. Nicholas, and M. B. Rashed. "Organic lead compounds in vehicle exhaust." Applied Organometallic Chemistry 2, no. 2 (1988): 95–100. http://dx.doi.org/10.1002/aoc.590020202.

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19

de Vos, D., W. A. A. van Barneveld, D. C. van Beelen, H. O. van Der Kooi, J. Wolters, and A. van Der Gen. "Aromatic lead(IV) compounds VII. The plumbylation of aromatic compounds." Recueil des Travaux Chimiques des Pays-Bas 94, no. 5 (September 2, 2010): 97–100. http://dx.doi.org/10.1002/recl.19750940505.

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20

Hanum, Laila, and Rina S. Kasiamdari. "Tumbuhan Duku: Senyawa Bioaktif, Aktivitas Farmaklogis dan Prospeknya dalam Bidang Kesehatan." JURNAL BIOLOGI PAPUA 5, no. 2 (October 14, 2018): 84–93. http://dx.doi.org/10.31957/jbp.528.

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Lansium domesticum Corr. (Meliaceae) is the popular tropical plant producing economic edible fruits found mainly in Southeast Asia. Seed, leaf, bark, stalks and fruit skin extracts of this plant are potential sources for compounds with broad spectrum of pharmacological activities such as antitumor, anticancer, antimalaria, antimelanogenesis, antibacteria and it may lead to the discovery of a new compouds used for antimutagenic and antioxidative stress. Bioactive compounds, pharmacological activities and prospect this plant in medical application will be discussed in this paper. Key words: Lansium domesticum, bioactive compounds, pharmacological activities, medical application.
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21

Akhmetkaliyeva, M. Sh, L. R. Sassykova, Y. A. Aubakirov, and G. R. Kosmambetova. "Fractional composition of compounds of zinc and lead in light chestnut soils." International Journal of Biology and Chemistry 10, no. 1 (2017): 89–91. http://dx.doi.org/10.26577/2218-7979-2017-10-1-89-91.

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22

Kuzmenko, A. P., E. A. Grechushnikov, V. A. Kharseev, M. B. Dobromyslov, and P. A. Rusanov. "Nanostructured Lead Compounds in Electrode Materials of a Lead-Acid Battery." Journal of Nano- and Electronic Physics 8, no. 4(1) (2016): 04046–1. http://dx.doi.org/10.21272/jnep.8(4(1)).04046.

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23

Strachotová, K. Ch, and M. Kouřil. "Effect of the presence of corrosion products on the corrosion rate of lead during the exposition with paper packaging materials." Koroze a ochrana materialu 62, no. 3 (July 1, 2018): 87–96. http://dx.doi.org/10.1515/kom-2018-0013.

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Abstract High sensitivity of lead to organic compounds leads to degradation of historical lead objects stored in the depositories of museums or archives. High concentration of organic compounds in the atmosphere of depositories is caused by degradation of organic materials (wood, glue, leather, paper). Organic materials are stored together with lead objects or they are used as a packaging material. This study was aimed on the influence of packaging material properties to aggressiveness towards lead with different state of surface by the resistometric method. The results showed that aggressiveness of packaging material is determined by a complex influence of material properties. The presence of corrosion products on the lead surface significantly increases its sensitivity to organic compounds.
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24

Tkachyshyn, V. S. "Intoxications by lead and its inorganic compounds." EMERGENCY MEDICINE 17, no. 4 (August 18, 2021): 6–12. http://dx.doi.org/10.22141/2224-0586.17.4.2021.237721.

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Lead belongs to the group of blood poisons that impair the synthesis of porphyrins and heme. Under industrial conditions, only chronic lead poisoning can develop. Lead belongs to the poisons that have the effect of material cumulation. The half-life of lead is 20 years. Once in the body, it is deposited in many organs in the form of the insoluble tribasic lead phosphates. A significant part of the lead is deposited in the trabeculae of the bones. Under the influence of provoking factors, an intensive lead release from the depot can be observed. In such cases, the amount of lead in the circulating blood increases sharply, and remission is replaced by an exacerbation. There is a wavy course of chronic lead intoxication. Lead and its inorganic compounds belong to the group of poisons that have a polytropic effect on the body, affecting many organs and systems. The blood system (anemia with specific characteristics) and the nervous system (polyneuropathy and encephalopathy) are primarily affected. A number of other organs and systems are also affected. The most severe specific syndrome of gastrointestinal tract damage is lead colic. Due to the impaired synthesis of porphyrins and heme in certain biological substrates of the body — in the blood, erythrocytes and urine, substances unused in the synthesis of heme are accumulated. They are markers of chronic intoxication caused by lead, in the presence of a relevant clinical picture. The diagnosis is based on data from a professional history, sanitary and hygienic characteristics of working conditions, clinical and objective characteristics of the disease and data from laboratory examination. The main thing is to stop contact with lead and remove it from the body. Antidotes for lead poisoning are chelators: tetacinum-calcium, pentacinum, D-penicillamine. In combination with technical and sanitary-hygienic measures to prevent chronic intoxication caused by lead, preliminary and periodic medical examinations of persons in contact with lead are of great importance.
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25

Alexandrescu, Irina, Carmen Teodosiu, and Alexandru Maftei. "ENVIRONMENTAL AND ECOTOXICOLOGICAL RISK OF LEAD COMPOUNDS." Environmental Engineering and Management Journal 2, no. 3 (2003): 255–70. http://dx.doi.org/10.30638/eemj.2003.024.

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26

PINTILIE, LUCIAN, MARIAN LISCA, and MARIN ALEXE. "LEAD-BASED FERROELECTRIC COMPOUNDS: INSULATORS OR SEMICONDUCTORS?" Integrated Ferroelectrics 73, no. 1 (September 2005): 37–48. http://dx.doi.org/10.1080/10584580500413434.

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27

Chandrasekhar, V., A. Chandrasekaran, Roberta O. Day, Joan M. Holmes, and Robert R. Holmes. "NOVEL CYCLIC PENTACOORDINATE AND PSEUDOPENTACOORDINATE LEAD COMPOUNDS." Phosphorus, Sulfur, and Silicon and the Related Elements 115, no. 1 (August 1, 1996): 125–39. http://dx.doi.org/10.1080/10426509608037960.

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28

Molina, L. M., J. A. Alonso, and M. J. Stott. "Assembling alkali–lead solid compounds from clusters." Journal of Chemical Physics 111, no. 15 (October 15, 1999): 7053–61. http://dx.doi.org/10.1063/1.479997.

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29

Shimoni-Livny, Liat, Jenny P. Glusker, and Charles W. Bock. "Lone Pair Functionality in Divalent Lead Compounds." Inorganic Chemistry 37, no. 8 (April 1998): 1853–67. http://dx.doi.org/10.1021/ic970909r.

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30

Golebiowski, Adam, Sean R. Klopfenstein, and David E. Portlock. "Lead compounds discovered from libraries: Part 2." Current Opinion in Chemical Biology 7, no. 3 (June 2003): 308–25. http://dx.doi.org/10.1016/s1367-5931(03)00059-0.

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31

Min, Yong Ki, Tadao Asami, Shozo Fujioka, Noboru Murofushi, Isomaro Yamaguchi, and Shigeo Yoshida. "New lead compounds for brassinosteroid biosynthesis inhibitors." Bioorganic & Medicinal Chemistry Letters 9, no. 3 (February 1999): 425–30. http://dx.doi.org/10.1016/s0960-894x(99)00008-6.

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32

Molina, L. M., J. A. Alonso, and M. J. Stott. "Building alkali-lead intermetallic compounds from clusters." Solid State Communications 108, no. 8 (October 1998): 519–24. http://dx.doi.org/10.1016/s0038-1098(98)00415-3.

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33

Scarisoreanu, N., F. Craciun, G. Dinescu, P. Verardi, and M. Dinescu. "Lead-based ferroelectric compounds deposited by PLD." Thin Solid Films 453-454 (April 2004): 399–405. http://dx.doi.org/10.1016/j.tsf.2003.11.183.

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34

Netzer, Rainer, Andreas Ebneth, Ulrike Bischoff, and Olaf Pongs. "Screening lead compounds for QT interval prolongation." Drug Discovery Today 6, no. 2 (January 2001): 78–84. http://dx.doi.org/10.1016/s1359-6446(00)01602-0.

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35

Smestad Paulsen, Berit. "Biologically active polysaccharides as possible lead compounds." Phytochemistry Reviews 1, no. 3 (October 2002): 379–87. http://dx.doi.org/10.1023/a:1026020404143.

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36

Nygren, Olle. "Stability of alkyl-lead compounds in blood." Applied Organometallic Chemistry 8, no. 7-8 (December 1994): 601–5. http://dx.doi.org/10.1002/aoc.590080709.

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37

Alwah R Al-Ghamdi, Iman S Issa, and Huda S Al-Salem. "Lead Compounds for Brain Protection against Alzheimer’s." International Journal of Science and Research Archive 10, no. 1 (October 30, 2023): 1029–57. http://dx.doi.org/10.30574/ijsra.2023.10.1.0214.

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To find a promising drug for treatment of Alzheimer’s` is not that easy target. Although some medications have FDA approval for management of AD, all of them offer symptomatic benefits. This is because efforts to find the treatment are distributed among many targets in the brain which make it so difficult to find a drug that can correct all of them at once. The primary histopathologic lesions of Alzheimer’s pathology are amyloid plaques, NFTs and neuronal loss with a wide genetic background which deteriorate the patient condition so rapidly. In the current article, we highlight some lead compounds that protect brain cells from undergoing this dark pathway or, which is more important, to stop deterioration and worsening of the case after starting of the disease. sex lead compounds of natural sources suggested as anti-AD drugs with brief discussion of each of them regarding its chemistry, physiochemical properties, mechanism of action, bioavailability, derivatives and method of synthesis. These natural extracts can be expected as lead compounds for design and synthesis of more effective derivatives as prophylactic treatment against Alzheimer’s. The aim of our review is to help to direct efforts to treat AD toward the prophylactic choice according to research results and scientific facts.
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38

Hafner, J. "Polyanionic clusters in liquid alkali-lead compounds." Journal of Non-Crystalline Solids 117-118 (February 1990): 64–67. http://dx.doi.org/10.1016/0022-3093(90)90879-q.

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39

Zheng, Zhi, Shumin Wang, Dapeng Li, Airuo Liu, Baojun Huang, Hongxiao Zhao, and Lizhi Zhang. "Morphology-controlled synthesis of lead iodine compounds from lead foils and iodine." Journal of Crystal Growth 308, no. 2 (October 2007): 398–405. http://dx.doi.org/10.1016/j.jcrysgro.2007.08.011.

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40

Goodenough, M., and K. J. Whitlaw. "The suppression of tin, lead and tin-lead electrodeposition by organic compounds." Transactions of the IMF 67, no. 1 (January 1989): 44–48. http://dx.doi.org/10.1080/00202967.1989.11870839.

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41

de Vos, D., H. O. van Der Kooi, J. Wolters, and A. van Der Gen. "Aromatic lead(IV) compounds VI. PMR spectroscopy of para-substituted aryllead compounds." Recueil des Travaux Chimiques des Pays-Bas 94, no. 5 (September 2, 2010): 94–97. http://dx.doi.org/10.1002/recl.19750940504.

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42

Agrawal, Krishn K., and Yogesh Murti. "LEAD PHYTOMOLECULES FOR HEPATOPROTECTIVE DRUG DEVELOPMENT." Indian Drugs 59, no. 02 (April 27, 2022): 7–26. http://dx.doi.org/10.53879/id.59.02.12700.

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Plants are the precious gift of nature to mankind and play a major role in the treatment of various diseased conditions from the ancient times. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. Natural products or their derivatives have led to many existing drugs, offering a chemically diverse space for discovery of hepatoprotective compounds. In order to represent the studies on chemical diversity of phytomolecules with hepatoprotective activity, this review is complied. This review captures a number of isolated phytomolecules having hepatoprotective potential. Phytomolecules as lead compounds for new drug discovery will boost up the researchers to work on it and find effective molecules for the treatment of liver injuries.
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43

Bagova, Z., K. Zhantassov, G. Turebekova, and B. Sapargaliyeva. "ANALYSIS AND IMPACT OF LEAD-CONTAINING WASTE FROM LEAD PRODUCTION ON HUMAN LIFE AND THE ENVIRONMENT." REPORTS 2, no. 336 (April 13, 2021): 99–104. http://dx.doi.org/10.32014/2021.2518-1483.36.

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As a result of the activities of the lead plant, about 2 million tons of waste in the form of lead- containing slags were accumulated. Lead production slags contain a large number of toxic heavy metal compounds, such as lead, zinc, osmium, and cadmium, which are dangerous sources of environmental pollution. Due to the open storage of slags, there is an excess of the maximum permissible concentrations (MPC) of lead: near the plant, the concentration of lead is more than 3000 mg/kg in the soil, with a MPC of 3.2 mg/kg. Lead and zinc compounds are dangerous to humans due to their significant toxicity and ability to accumulate in the body. Lead poisoning ranks first among professional intoxications. Waste water containing zinc compounds is not suitable for irrigation of fields, the negative effect of zinc compounds on microorganisms and microfauna of the soil reduces its fertility. The article presents the results of scientific studies of lead slag, conducted by scanning electron microscopy and X-ray microanalysis, performed on a scanning electron microscope (SEM) JEOL-6490 LV (Manufacturer: JEOL, Japan). The results of the thermal analysis of samples on the derivatograph of the F. Paulik, J. Paulik and L. Erdey system in the air environment, in the temperature range of 20-1000°C. are presented. According to the results of research, it was found that lead slags contain a sufficiently high amount of non- ferrous metal compounds: lead oxide up to 0.7 % and zinc oxide up to 8.5 % of the weight amount of slag, which makes the process of recycling toxic waste from lead production technically and economically feasible.
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44

Vellaisamy, M., and R. Geetha. "Green Synthesis and characterization of Lead Oxide Nanoparticles using Piper Betle leaf." Research Journal of Chemistry and Environment 26, no. 11 (October 25, 2022): 38–42. http://dx.doi.org/10.25303/2611rjce038042.

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Lead oxide nanoparticles were synthesized by using cost effective and eco friendly green method assisted by piper betle leaf extract. The UV absorption spectrophotometer analysis of leaf extract and metal compounds showed absorbance spectra in the range 300-400 nm. The UV-Vis spectroscopy shows Surface Plasmon resonance of PbO nanoparticles at 320 nm indicating that the particles are poly dispersed. The FT-IR measurements were carried out to identify the formation of lead oxide nanoparticles and possible molecules such as OH, C=C, C=O and aromatic compounds. The FT-IR analysis played a pivoted role in displaying the nanoparticles which showed strong absorbance in the range 518-600 cm-1 for lead oxide nanoparticles. The diffraction peaks and planes of ions are indexed. From the ‘X’ ray diffraction analysis, the size of the lead oxide nanoparticles is 70 nm as calculated by Debye scherrer’s equation. The size, shape and structure of nanoparticles were also analyzed by Scanning electron microscope showing tetragonal shape of nanoparticles aggregation. This green synthesis method has many advantages over the chemical method because it reduces the use of toxic metals in the synthesis process.
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45

Han, Kyoung R., Hee Jin Koo, and Chang Sup Lim. "Novel Route to Lead-Based Ferroelectric Compounds via Tetragonal Lead(II) Oxide Intermediates." Journal of the American Ceramic Society 83, no. 9 (December 20, 2004): 2214–18. http://dx.doi.org/10.1111/j.1151-2916.2000.tb01537.x.

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46

Zhang, Yu, Jinchang Sun, Jing Shuai, Xinfeng Tang, and Gangjian Tan. "Lead-free SnTe-based compounds as advanced thermoelectrics." Materials Today Physics 19 (July 2021): 100405. http://dx.doi.org/10.1016/j.mtphys.2021.100405.

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47

Cerecetto, H., R. Di Maio, G. Seoane, A. Denicola, G. Peluffo, and C. Quijano. "Synthetic Modifications of Lead Compounds as Antitrypanosomal Drugs." Molecules 5, no. 12 (March 22, 2000): 497–98. http://dx.doi.org/10.3390/50300497.

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48

Scala, Fernando, Ernesto Fattorusso, Marialuisa Menna, Orazio Taglialatela-Scafati, Michelle Tierney, Marcel Kaiser, and Deniz Tasdemir. "Bromopyrrole Alkaloids as Lead Compounds against Protozoan Parasites." Marine Drugs 8, no. 7 (July 14, 2010): 2162–74. http://dx.doi.org/10.3390/md8072162.

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49

Leon-Gonzalez, Antonio, Nuria Acero, Dolores Munoz-Mingarro, Inmaculada Navarro, and Carmen Martin-Cordero. "Chalcones as Promising Lead Compounds on Cancer Therapy." Current Medicinal Chemistry 22, no. 30 (October 19, 2015): 3407–25. http://dx.doi.org/10.2174/0929867322666150729114829.

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50

Krempaská, Klára, Ladislav VaŠko, and Janka VaŠková. "Humic Acids as Therapeutic Compounds in Lead Intoxication." Current Clinical Pharmacology 11, no. 3 (September 20, 2016): 159–67. http://dx.doi.org/10.2174/1574884711666160813233225.

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