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1
Poukarová, Hana. "Homeopatická léčba v České republice." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-162466.
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My thesis is divided into three parts. In the technology part are summarized knowledge of homeopathy and its principles with regard to research in this area, in the second part is mapped the availability of entities of homeopathic treatment. The last part focuses on the cost effectiveness of treatment of acute illnesses typical for winter season.
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Rabiňáková, Veronika. "Význam organizace Teen Challenge International pro lidi ohrožené závislostí či se závislostí bojující." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-297462.
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TITLE: The impact of Teen Challenge International on individuals endangered by an addiction or fighting with an addiction, or God as Hope KEY WORDS: Drugs Addiction Prevention Cure Teen Challenge International Belief in God ANNOTATION: In my diploma I observe how cognition of God and belief in Him influences the process of prevention of addiction and the help provided for drug addicts. The theoretical part deals with the issue of drug addiction in the Czech Republic, with strategies fighting this phenomenon, and with various types of help which works, at least to a certain extent, with the spi
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Vignati, Michaela. "Léčba obezity." Master's thesis, 2010. http://www.nusl.cz/ntk/nusl-277969.
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12. SUMMARY Ever before we are accompanied by an obesity. At present days we are witnesses of sharp accrual of an obesity in all parts of the world. Unfortunately even the Czech republic is not an exception. Above all an obesity is defined as an excessive amount of fat in a relation to other tissues of organism and brings relevant medical and physical risks. Among basic factors which cause formation of an obesity influences of outside surroundings and genetic predesposition can be reckoned. To develop suitable therapeutic procedure it is necessary to do: anamnestic, anthropometric, biochemical
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Pavlíčková, Iva. "Léčba insomnie." Master's thesis, 2010. http://www.nusl.cz/ntk/nusl-282923.
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Název práce: Léčba insomnie Autor: Iva Pavlíčková Škola: UK v Praze, Farmaceutická fakulta v Hradci Králové Studijní obor: Farmacie Katedra: Katedra farmakologie a toxikologie Školitel: PharmDr. Ludmila Melicharová Počet stran: 67 Rok obhajoby: 2010 Abstract: Insomnia is prevalent in many populations, both as a primary disorder and as a symptom of many medical and psychiatric conditions. In this thesis there are summarized the most important aspects of treatment of insomnia. There are introduced basic characteristics of insomnia, its possible causes, brief summary of insomnia treatment. This t
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Trávníčková, Jana. "Léčba epilepsie." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-297150.
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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of pharmacology and toxicology Candidate: Jana Trávníčková Supervisor: PharmDr. Ludmila Melicharová Title of diploma thesis: Pharmacotherapy of epilepsy Epilepsy is one of the most frequent central nervous system diseases. This disorder is characterized by repetitious epileptic spasms. Classic as well as modern antiepileptic medication is being used in nowadays therapy with various effects, indications and adverse effects. Pharmacotherapy must always be continuous and long-term based, sometimes even long-life. In som
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Juřičková, Markéta. "Léčba deprese." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-312696.
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School: Charles University in Prague Faculty: Faculty of Pharmacy in Hradec Králové Study program: Pharmacy Department: Department of pharmacology and toxicology Academic year: 2010/2011 Author: Markéta Juřičková Supervisor: PharmDr. Ludmila Melicharová Title of diploma thesis: The pharmacotherapy of the depression This diploma thesis deals with the characterization of depression including its pathophysiology, causes, symptoms, progress as well as it classifies the types of depressive disorders. The diploma thesis deals with the treatment of depression, selection of antidepressants, using of a
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Hlinková, Lucie. "Léčba schizofrenie." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-324594.
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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Student: Lucie Hlinková Supervisor: Prof. MUDr. Radomír Hrdina, CSc. Title of diploma thesis: Treatment of schizophrenia Schizophrenia is a serious mental disease, mostly chronic. It affects about 1 % of population, first episode of the disease occurs mostly between the age of 15 and 35. It manifests itself with disorders of perception, behavior and thinking. The specific symptoms include hallucinations, delusions, disorganized speech and behavior, catatonia, disorders of attention and vo
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Chaloupková, Lucie. "Léčba epilepsie." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-330759.
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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Student: Lucie Chaloupková Supervisor: Prof. MUDr. Radomír Hrdina, CSc. Title of diploma thesis: Treatment of epilepsy Epilepsy is a serious chronic disease affecting all ages which can be characterized by recurrent epileptic attacks. It affects about 1,3-4 % of the population and endangers the patient's life at every incoming attack. Long-term treatment must be preceded by thorough diagnosis and classification of the disease, which can be very difficult. The aim of the treatment is to pr
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Brožová, Lenka. "Léčba astmatu." Master's thesis, 2008. http://www.nusl.cz/ntk/nusl-292536.
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Asthma bronchiale is a very common chronic disorder of airways with not fully elucidated pathology, which is not fully curable at the moment. It is estimated that 300 millions of persons suffer from asthma. About 8% of adult population and 10% of children are affected in the Czech republic. The aim of this thesis is to give an overview of contemporary modern pharmacotherapy of asthma. Firstly, this work describes asthma from pathophysiological and epidemiological point of view, among others: risk factors, used classification of asthma and its clinical diagnosis. The main emphasis is given part
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Černá, Hana. "Léčba migrény." Master's thesis, 2008. http://www.nusl.cz/ntk/nusl-292558.
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In this thesis there are summarized the most important aspects of treatment of migraine. The initial step in treatment of migraine should be proper diagnosis of migraine headaches and triggering factors. Successful disease management is complex, must combine pharmacologic and non- pharmacologic approach, change of lifestyle and nutrition. Good cooperation between the doctor and the patient should be considered under the treatment success. Development of a new type of pharmaceuticals called "triptans" caused the substantial progress. It presents the most effective class of pharmaceuticals and t
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Čudová, Martina. "Léčba astma bronchiale." Master's thesis, 2009. http://www.nusl.cz/ntk/nusl-279063.
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Topic: Therapy of asthma bronchiale Author: Martina Čudová Bronchial asthma is a lifetime chronical inflammatory disease of the airways. Chronical inflammation is linked to bronchial hyperreaktivity and both lead to reversible and variable obstruction of airways. The prevalence of this disease has been increasing in recent years, mainly in children and teenagers, where asthma becomes the most frequent disorder. Asthma isn't curable, but thanks to opportune diagnosis and correctly configured treatment, the patient can be absolutely without difficulties. Conversely, untreated asthma leads to irr
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Houdková, Andrea. "Léčba Alzheimerovy choroby." Master's thesis, 2010. http://www.nusl.cz/ntk/nusl-279077.
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4 ABSTRACT Topic: Treatment of Alzheimer's disease Author: Andrea Houdková Alzheimer's disease is a progressive neurodegenerative disease. Its symptoms are the disorders of memory, speech, executive functions and disorientation. In the terminal stage the patients suffering from this disease are fully dependent on help of other people. Alzheimer's disease is incurable but early diagnosis and consequently started therapy can postpone the heavy stages of the disease and prolong the self - sufficiency of patients. Currently two evidence based methods in the therapy of cognitive disorders are used:
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Kučerová, Marika. "Léčba roztroušené sklerózy." Master's thesis, 2009. http://www.nusl.cz/ntk/nusl-279464.
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Multiple sclerosis treatment Multiple sclerosis is an autoimmune inflammatory and neurodegenerative disease that affects central nervous system and continuously worsen physical and cognitive abilities of the patients. The causal therapy has not been found yet; the disease could be influenced by immunomodulation, immunosuppression and cytostatic treatment. In the first phase of the disease mainly the inflammatory processes are present. The manifestation of these is the attack of increased neurological deficite. The attack of multiple sclerosis is usually treated by the intravenous infusion of h
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Sakač, Jiří. "Léčba peptických vředů." Master's thesis, 2009. http://www.nusl.cz/ntk/nusl-282932.
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Topic: Treatment of peptic ulcers Autor: Jiří Sakač Peptic ulcers represent one of the most widespread gastrointestinal disease all over the world. It occurs the most in the middle and high aged people. It is a multifactorial disease, which is developed by dysbalanc between agresive and protective factors. Its occurrence and incidence is associated with presence of the infection Helicobacter pylori in gastrointestinal tract. H. pylori is the main risk faktor for a diverse spectrum of gastrointestinal diseases, and it makes first damage of mucous membrane. Comprehensive individual treatment con
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Veselá, Michaela. "Léčba Alzheimerovy choroby." Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-305780.
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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxikology Student : Michaela Veselá Supervisit : PharmDr. Ludmila Melicharová Title of diploma thesis : The therapy of Alzheimer's disease Alzheimer's disease is becoming more pressing problem of today's population. It is very serious progressive-neurodegenerative disorder mainly manifested by memory loss, cognitive dysfunction and personality changes. This thesis provides topical summary of the most important aspects of treatment of Alzheimer's disease. There are introduced basic characteristics o
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Jirásková, Petra. "Biologická léčba astmatu." Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-307848.
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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Student: Petra Jirásková Supervisor: PharmDr. Jana Pourová, Ph.D. Title of diploma thesis: BIOLOGICAL THERAPY OF ASTHMA This thesis provides an overview of approaches to biological treatment of asthma. The first part deals with a brief description of the disease, and further gives basic information on the preparation of monoclonal antibodies, their structure and mechanisms of action. The second part of this work is focused on biological treatment. Biologics are divided into groups accordi
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Hanzlíková, Pavla. "Léčba tromboembolické nemoci." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-296440.
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Topic: Treatment of venous thromboembolism Author: Pavla Hanzlíková Venous thromboembolism is the designation for the states in which a new rising thrombus in the peripheral venous bloodstream can reach the pulmonary artery. These include deep vein thrombosis or phlebothrombosis legs and pulmonary embolism. Clinically, this is absolutely a different disease, but which are closely related and often occur together and have the same treatment. Anticoagulants, fibrinolytic, antiplatelet therapy with adenosine diphosphate receptor blockers, inhibitors of platelet glycoprotein receptor IIb / IIIa an
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Jůzková, Anežka. "Léčba revmatoidní atritidy." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-297183.
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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Candidate: Anežka Jůzková Supervisor: PharmDr. Ludmila Melicharová Title of diploma thesis: The pharmacotherapy of rheumatoid arthritis Abstract: The diploma thesis summarizes current knowledge on rheumatoid arthritis treatment and presents possibilities of further development. It focuses in detail on individual pharmacotherapeutic groups and their ability to influence the progression of the disease and patient's quality of life. It also refers to treatment during pregnancy and lactatio
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Mlčochová, Michaela. "Léčba arteriální hypertenze." Master's thesis, 2008. http://www.nusl.cz/ntk/nusl-292481.
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Topic: Therapy of arterial hypertension Author: Michaela Mlčochová Arterial hypertension is one of the most common diseases of cardiovascular system. Long-lasting high blood pressure is associated with development of organ damage and adverse prognosis. Accurate diagnosis and precision treatment decrease markedly the risk of hypertensive and atherosclerotic complications such as coronary heart disease, cerebrovascular events, heart failure and end-stage renal disease. Most of the hypertensive patients require pharmacological treatment to attain recommended levels of blood pressure. Lifestyle mo
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Hrouzková, Šárka. "Léčba diabetes mellitus." Master's thesis, 2008. http://www.nusl.cz/ntk/nusl-292553.
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DM is metabolic disorder characterized with hyperglycaemia at absolute shortage of endogenous insulin (DM1T), or at its relative shortage (DM2T). DM1T is a symptom of B-cell destruction in islets of pancreas Langerhans that occurs mostly on autoimmune basis. Lack of insulin results in disorder of glucose use and in increased catabolism of fat and proteins. The result of this disorder is hyperglycaemia, glycosuria, polyuria, thirst, eventually ketoacidotic coma. DM2T which prevalence is continuously increasing represents significant medical, social and economic problem. DM2T develops due to ins
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Šumpichová, Veronika. "Léčba revmatoidní artritidy." Master's thesis, 2008. http://www.nusl.cz/ntk/nusl-292563.
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Summary: Approximately 1% of population around the world is currently suffering of rheumatoid arthritis. It is an autoimmune chronical inflamatory disease that affects joints. However, usually also other tissues or systems are affected. The crucial is an oblique immune process when the body is responding to the unknown factor by creating antibodies and destroying itself. The development of the disease can be affected by combination of genetic predisposition and until now non-indetified agent or agents. Moreover, the general influence on disease have female gender, positive family history, effe
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Krůpa, Petr. "Experimentální léčba poranění míchy a klinická léčba hrudně-bederních obratlových zlomenin." Doctoral thesis, 2019. http://www.nusl.cz/ntk/nusl-409195.
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Vertebral body fractures together with the spinal cord injury (SCI) remain a challenging medical condition. While management of the thoracic-lumbar (Th-L) vertebral fractures belongs to basic neurosurgical procedures with a usually excellent outcome, treatment of the severe spinal cord injury has mostly unsatisfactory results and thus novel approaches are highly in demand. In this study, experimental treatment of the SCI in a rat model using human mesenchymal stem cells derived from Wharton's jelly (WJ-MSCs) and a novel highly water soluble, nano-formulated curcumin is evaluated. Furthermore,
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Šlachtová, Barbora. "Biologická léčba renálního karcinomu." Master's thesis, 2014. http://www.nusl.cz/ntk/nusl-337081.
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Charles University in Prague, Faculty of Pharmacy in Hradec Králové Deparment of: Department of Biological and Medicinal Sciences Head of the thesis: PhDr. Zdeňka Kudláčková, Ph.D. Consultant: MUDr. Jakub Cvek, Ph.D. Student: Barbora Šlachtová Title of Thesis: Renal cell carcinoma treatment - biological therapy Background: The aim of this thesis was to become more familiar with the issue of renal cancer, treatment options, focusing on targeted therapy and its specific products, comparing results from registration studies and RENIS database and evaluating results of targeted therapy in clinical
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Bradáč, Ondřej. "Léčba arteriovenózních malformací mozku." Doctoral thesis, 2015. http://www.nusl.cz/ntk/nusl-349361.
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Introduction: The surgical and endovascular results of the treatment of pial AVM provided at our Neurosurgical centre are presented. These results are supported by neuropsychological outcomes of subgroup of treated patients. Going by these results and by an overview of literary data on the efficacy and complications of each therapeutic modality, the optimal algorithm of indications is presented Cohort of patients: The main series comprises 222 patients aged 9 to 87 years treated in the years 1998 - 2013. The surgical group consists of 85 patients, 55 patients received solely endovascular treat
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Paluch, Zoltán. "Antiagregační léčba ve stáří." Doctoral thesis, 2008. http://www.nusl.cz/ntk/nusl-292854.
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The aim of our study was to determine the efficacy of antiplatelet therapy in elderly and polymorbid patients. We were interested to know whether selected laboratory parameters, co-existing conditions, and concomitant therapy may affect the antiplatelet effect of low-dose acetylsalicylic acid. In our study groups, we demonstrated high urinary levels of 11-dehydrothromboxane B2 suggesting ineffective antiplatelet therapy. In our series, its prevalence was in excess of 46%. A comparison of groups of aspirin-sensitive and aspirin-resistant patients revealed statistically significant differences i
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Bártová, Lenka. "Léčba karcinomu děložního čípku." Master's thesis, 2010. http://www.nusl.cz/ntk/nusl-279052.
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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of farmakology and toxikology Author: Lenka Bártová Director of my diploma work: PharmDr. Ludmila Melicharová Title of diploma work: The therapy of the cervical cancer This diploma work describes the possibilities of prevention and medical treatment of the cancer of the uterine uvula. The theoretical part contains the fundamental information about this disease, prevention and medical procedures. The inseparable part of this diploma work forms also the Questionnaire, reflecting the knowledge of women regarding the can
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Havelková, Olga. "Patofyziologie a léčba migrény." Master's thesis, 2009. http://www.nusl.cz/ntk/nusl-279867.
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Summary: Title: The pathophysiology and treatment of migraine Author: Olga Havelková Supervisor: Doc. MUDr. Josef Herink, DrSc. Department: Department of biological and medicinal science Migraine is chronic multifactorial disease. It is characterized as attacks of pulsating headache. Attack is often accompanied with vomiting, nausea and phonophobia or photophobia. Therapy of migraine consists in prophylaxis of provoking factors and in medicamentous treatment. Present thesis describes provoking factors, pathophysiology and principles of prophylaxis and treatment of migraine.
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Hamalová, Kateřina. "Léčba chorob respiračního traktu." Master's thesis, 2009. http://www.nusl.cz/ntk/nusl-282948.
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RESPIRATON TRACT DIEASES TREATMENT Diploma theasis Kateřina Hamalová Charles University in Prague, Faculty of Pharmacy in Hradec Králové We experience respiration tract diseases very often. Infection of ventral respiratory ways (laryngotracheitis, tracheobronchitis, pneumonia etc.), lung disease with bronchial obstruction (CHOPN, asthma), interstitial processes of unknown etiology and bronchial carcinoma belong to this group of diseases. Asthma bronchiale is one of the diseases affecting a substantial part of the world's population. It is a chronic inflammatory disease of respiratory ways. Chr
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Libichová, Iva. "Biologická léčba patologických stavů." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-296827.
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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Title of diploma thesis: Biological therapy of pathological disorders Author: Iva Libichová Supervisor: PharmDr. Marie Vopršálová, CSc. Email of supervisor: Marie.Voprsalova@faf.cuni.cz Abstract The aim of this thesis is to give a comprehensive overview of current options of biological therapy. Since this course of study is relatively new, biologics are described from common point of view including their manufacture. The major part is dedicated to individual categories of biologics. How
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Martincová, Petra. "Farmakologická léčba roztroušené sklerózy." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-322700.
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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Student: Mgr. Petra Martincová Supervisor: Prof. PharmDr. František Štaud, Ph. D. Title of diploma thesis: Pharmacology treatment of multiple sclerosis Multiple sclerosis is a neurological inflammatory disease of central nervous system of an autoimmune origin with several subtypes according to different clinical courses. The main philosophy of a treatment is based on an early administration of anti-inflammatory treatment. This can delay irreversible neurodegeneration and disability of p
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Juhász, Jan. "Léčba ischemické choroby dolních končetin." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-397889.
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Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Student: Jan Juhász Supervisor: Prof. MUDr. Radomír Hrdina, CSc. Title of diploma thesis: Treatment of lower extremity peripheral artery disease The lower extremities ischemia is a disease caused most often by atherosclerosis during which the lumen in lower limb arteries becomes narrow. Its prevalence is increasing, especially in the developed countries. The disease can be asymptomatic and symptomatic. The symptoms are very unpleasant and decrease patient's quality of life. Advanced stages of the
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Kůdelová, Marie. "Asistovaná reprodukce jako léčba neplodnosti?" Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-434221.
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This work "Is assisted reproduction a therapy for infertility?" deals with methods of assisted reproduction. The aim is not only to elucidate its techniques but also to open some difficult ethical questions. This work shows why we cannot regard assisted reproduction as a legitimite treatment for infertility and suggests alternative procedures. The first chapter is about the individual human life seen from the perspective of various sciences. The second chapter is about causes of infertility and about possibilities of its treatment. The third chapter deals with various methods of artificial rep
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Formáčková, Jitka. "Marná léčba v intenzivní péči." Master's thesis, 2014. http://www.nusl.cz/ntk/nusl-337098.
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V ANGICKÉM JAZYCE THE FUTILE TREATMENT IN THE INTENSIVE CARE The theoretical part is define the concept of the futile treatment, analyze its legal and ethical context, especially within nursing and medical interventions, categorize the treatment and summarize the procedure of making decisions of changing the treatment in the Czech Republic. The purpose of the theoretical part is mapping the situations when the intensive care is pointless and how to proceed in the situations like these. The practical part will process a qualitative research by a form of personal interviews with several represen
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Aboutable, Tarek. "Chirurgická léčba diabetického makulárního edému." Doctoral thesis, 2006. http://www.nusl.cz/ntk/nusl-266099.
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Diabetic macular edema is the most common cause of visual impairment in diabetic patients. Precise pathophysiology of diabetic macular edema is unclear and seems to be multifactorial and includes pericyte loss, microaneurysm formation, basement membrane thickening and focal closure of the capillary bed, vitreomacular traction, and ultimately breakdown of the blood-retinal barrier with increased vascular permeability. Risk factors for clinical significant diabetic macular edema are hyperglycemia, hypertension, hyperlipidemia, duration of diabetes, and pregnancy. The increasing number of individ
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Herlesová, Jitka. "Psycholog a bariatrická léčba obezity." Doctoral thesis, 2017. http://www.nusl.cz/ntk/nusl-371322.
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Psychologist and bariatric tretment of obesity PhDr.Jitka Herlesová Tutor: PhDr.Tamara Hrachovinová, CSc. Abstract The aim of the dissertation thesis is to map psychosocial characteristics associated with obesity and their changes after bariatric surgery. The Empirical part follows the points settled in the Theoretical part. Obesity is a disease, whose prevalence rises. Bariatric and metabolic surgery is one of the most effective treatment of obesity and its comorbidities. The mental diseases are associated with high levels of obesity. The standard part of pre-bariatric examination is the psyc
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Vrbová, Aneta. "Léčba diabetes mellitus perorálními antidiabetiky." Master's thesis, 2009. http://www.nusl.cz/ntk/nusl-279093.
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Oral antidiabetics treatment is an integral part of complex therapy in type 2 diabetic pacients. This thesis provides a topical/up-to-date summary of diabetes pharmacology and of clinical application of oral antidiabetic agents. The individual chapters deal with single groups of used oral antidiabetic agents. Finally, the thesis outlines possibilities of pharmacotherapy of diabetes mellitus by new antidiabetic preparations.
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Nagyová, Lucie. "Léčba opakujících se chronických ran." Master's thesis, 2010. http://www.nusl.cz/ntk/nusl-279504.
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Lucie Nagyová Treatment of recurrent chronic wound Diplomová práce Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové Studijní obor: Farmacie The aim of this work is understanding to recurrent chronic wound healing processes, with a view to chronic diabetic foot ulcer (DFU) and ways of its treatment. The purpose is to find, how treatment of chronic DFU is conducted in current clinical practise and then compare this finding with theory. We chose a group of twenty patiens incidentally, and we made a brief analysis of chronic DFU treatment based on information taken from patients'
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Zubíková, Markéta. "Léčba dekubitů metodou vlhkého hojení." Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-347520.
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Bc. Markéta Zubíková Treatment of decubitus using moist wound healing method Diploma thesis Charles University in Prague, Faculty of Pharmacy in Hradec Králové Specialist in laboratory methods The thesis deals with decubitus and method of moist wound healing. The treatment of pressure ulcers is still a hot topic that falls into the problems of modern nursing. Decubitus ulcers are chronic wounds caused by pressure. An important role is prevention, which is based on positioning, rigorous hygiene of the patient, modified bed and use of anti-decubitus aids. Treatment of pressure ulcers is long and
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Durasová, Lenka. "Léčba dyslipidémií z pohledu farmaceuta." Master's thesis, 2006. http://www.nusl.cz/ntk/nusl-272183.
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Kněžíková, Tereza. "Motolice jaterní - léčba a rezistence." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-370978.
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Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Student: Tereza Kněžíková Supervisor: PharmDr. Ivan Vokřál, Ph.D. Title of diploma thesis: Liver fluke - treatment and resistence Fasciola hepatica is a parasite of global importance that we find both in farm animals and in humans. This thesis aims to summarize information on the potential of drugs and treatment alternatives that are suitable for treatment of F. hepatica. Given that for a number of drugs used in the past, as well as the drugs currently administered, resistance developed, this the
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Veliká, Věra. "Léčba keratokonu metodou akcelerovaného crosslinkingu rohovky." Doctoral thesis, 2019. http://www.nusl.cz/ntk/nusl-392657.
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Summary: Treatment of keratoconus using Accelerated Corneal Cross-Linking Aim: This study evaluates the efficacy of treatment of progressive keratoconus using Accelerated Corneal Cross-linking (ACXL) method. Methods: The study included 35 eyes of 32 patients, who underwent ACXL at the Deparment of Ophthalmology of University Hospital in Hradec Králové. Uncorrected distance visual acuity (UCVA), best corrected distance visual acuity (BCVA), flat and steep keratometry (K1, K2), maximum keratometry (Kmax), corneal astigmatism and corneal pachymetry in the thinnest location were measured preoperat
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Vacková, Zuzana. "Achalázie jícnu - etiologie, patofyziologie a léčba." Doctoral thesis, 2020. http://www.nusl.cz/ntk/nusl-437103.
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Background: Achalasia is a primary esophageal motility disorder that can be classified into three types (I-III) based on high-resolution manometry (HRM). Exact pathogenesis is unknown, but immune-mediated processes and genetic predisposition play a role, which is supported by finding of a genetic risk variant (rs28688207 insertion) in HLA-DQB1 gene that is strongly associated with achalasia. Per-oral endoscopic myotomy (POEM) has become a standard treatment for achalasia, but the long-term efficacy, safety and impact on esophageal physiology are not fully understood. The aims of our studies we
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Porzerová, Miroslava. "Léčba a prevence recidiv nosní polypózy." Master's thesis, 2007. http://www.nusl.cz/ntk/nusl-271641.
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Nasal polyposis , although it is a benign disease , is an important medical problem , especially unpleasant subjective perception of disease patient and the frequency of relapses of the disease , the monitoring we In the present work studied . There are many different definitions of the disease , generally recognized consensus of specialists dealing with nasal polyposis is characterized by nasal polyps oedematous mucosa as pouches which may be present to a varying extent from a polyp to diffuse polyposis , and that besides the nasal cavity can also affect paranasal sinuses. The etiology of nas
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Votavová, Dominika. "Léčba a prevence recidiv nosní polypózy." Master's thesis, 2009. http://www.nusl.cz/ntk/nusl-284880.
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Nosní polypóza je sice onemocněním benigním, ale výrazně ovlivňuje kvalitu života. Zdá se, že není onemocněním per se, ale že se spíše jedná o výsledek nebo o vyjádření chronických zánětlivých procesů probíhajících na sliznici dutiny nosní a VDN. Patogeneza NP zůstává přesto neznámá. Prevalence výskytu Staphylococcus aureus u pacientů s nosní polypózou je vysoká. Nové studie prokázaly výskyt IgE protilátek ve tkáni polypu, zaměřených proti stafylokokovým enterotoxinům (SAE). Avšak role Staphylococcus aureus v rozvoji tohoto onemocnění je s největší pravděpodobností minimální. Za základ terapie
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Libánský, Petr. "Diagnostika a chirurgická léčba primární hyperparathyreózy." Doctoral thesis, 2010. http://www.nusl.cz/ntk/nusl-299141.
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Surgical management of primary hyperparathyroidism is a very effective method. The target is to cure primary hyperparathyroidism and to reach normal calcium levels. This results in an improvement of health condition and resolution or at least moderation of symptoms. Complications are infrequent and mortality is very low. Surgical management is definite, safe and effective. Number, location and surrounding structures of parathyroid glands with emphasis on parathyroidectomy were studied on 101 cadaverous bodies. We recommend the performance of parathyroidectomy in a circumscribed area 2 cm in di
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Ackermannová, Veronika. "Topická a systémová léčba acne vulgaris." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-411902.
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Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Student: Veronika Ackermannová Supervisor: prof. Radomír Hrdina, MD, CSc. Title of diploma thesis: Topic and systemic treatment of acne vulgaris Acne vulgaris is a skin disease affecting the hair follicles and sebaceous glands. The disease manifests itself by increased sebum production, non-inflammatory (comedones) and inflammatory lesions (papules, pustules, nodules, cysts). It occurs predominantly in adolescents, but may persist into adulthood. It is a multifactorial disease, which is caused by
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Lipina, Radim. "Endoskopická léčba posthemoragického hydrocefalu nezralých novorozenců." Doctoral thesis, 2009. http://www.nusl.cz/ntk/nusl-273649.
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Endoscopic treatment for posthemorrhagic hydrocefalus in premature newborns Abstract Introduction: Up to date the pathophysiology of posthemorrhagic hydrocephalus (PHH) in premature newborns is explained as a consequence of cytokine TGF β1 release into cerebrospinal fluid (CSF) during initial bleeding, followed by induction of "inflamatory proteins" in subarachnoideal spaces. Method of choice in treatment of PHH is ventriculo-peritoneal drainage. The role of endoscopic third ventriculostomy (ETV) in these patients is unclear, through obstruction is proved in some patients with PHH. The aim of
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Malý, Jan. "Imunosupresivní léčba Crohnovy nemoci u dětí." Doctoral thesis, 2009. http://www.nusl.cz/ntk/nusl-281048.
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Crohn disease (CD) treatment in children doesn't differ from adults today. The main role in management of disease play systemic corticosteroids (CS) and immunesupressants. Aims: 1) evaluate efficacy and hepatotoxicity of 6-thioguanine (6-TG) on mice model of experimental colitis. 2) evaluate time to steady state of 6-thioguanine nucleotides after azathioprine (AZA) treatment initiation in children with inflammatory bowel disease (IBD). 3) evaluate dose (incl. cumulative dose) of CS applied through the first year after diagnosis according to disease activity. 4) AZA steroid sparing effect analy
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Sadloňová, Jana. "Epidemiologie, diagnostika a léčba děložních myomů." Doctoral thesis, 2008. http://www.nusl.cz/ntk/nusl-291412.
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Knězů, Michaela. "Léčba vředové choroby žaludku a duodena." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-296798.
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School: Charles University in Prague Faculty: Faculty of Pharmacy in Hradec Králové Study program: pharmacy Department: Department of pharmacology and toxicology Academic year: 2010/2011 Author: Michaela Knězů Supervisor: PharmDr. Ludmila Melicharová Title of diploma thesis: The pharmacotherapy of gastric and duodenal ulcer disease This diploma thesis deals with a gastric and duodenal ulcer disease. The aim of this work is to make summary of pharmaceutics used in therapy with concentrating on its mechanisms of action, pharmacokinetics, side effects and drug interactions. Nowadays antacids, ant