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1

Reddy Jala, R. C., B. Chen, H. Li, et al. "Enzymatic preparation and characterization of soybean lecithin-based emulsifiers." Grasas y Aceites 67, no. 4 (2016): 168. http://dx.doi.org/10.3989/gya.0571161.

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Simple enzymatic methods were developed for the synthesis of lysolecithin, glycerolyzed lecithin and hydrolyzed lecithin. The products were characterized in terms of their acetone insoluble matter, hexane insoluble matter, moisture, phospholipid distribution and fatty acid composition. The HLB value ranges of different products with different acid values were detected. The efficiency of optimally hydrolyzed lecithin was examined at high calcium ion, low pH, and aqueous solutions and compared with commercially available standard lecithin-based emulsifiers. Overall, lysolecithin powder was prove
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2

Chiplunkar, Pranali P., and Amit P. Pratap. "Ultrasound Assisted Synthesis of Hydroxylated Soybean Lecithin from Crude Soybean Lecithin as an Emulsifier." Journal of Oleo Science 66, no. 10 (2017): 1101–8. http://dx.doi.org/10.5650/jos.ess17090.

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3

Letona, Carlos, Ke Luo, Ki-Baek Jeong, Hazzel Adra, Cheon-Seok Park, and Young-Rok Kim. "Effect of Lecithin on the Spontaneous Crystallization of Enzymatically Synthesized Short-Chain Amylose Molecules into Spherical Microparticles." Polymers 11, no. 2 (2019): 264. http://dx.doi.org/10.3390/polym11020264.

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Here, we report a facile and effective one-pot approach to prepare uniform amylose-based polymeric microparticles (PMPs) through enzymatic synthesis of short-chain amylose (SCA) followed by spontaneous self-assembly of the SCA in the presence of lecithin. The effect of lecithin on nucleation and growth kinetics of amylose microparticles was investigated by monitoring the turbidity of reaction solution and the size of particles over the course of the self-assembly process. The results suggest that lecithin played a critical role in controlling the self-assembly kinetics to form uniform amylose
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4

Ding, Guan-Jun, Ying-Jie Zhu, Chao Qi, Bing-Qiang Lu, Feng Chen, and Jin Wu. "Porous hollow microspheres of amorphous calcium phosphate: soybean lecithin templated microwave-assisted hydrothermal synthesis and application in drug delivery." Journal of Materials Chemistry B 3, no. 9 (2015): 1823–30. http://dx.doi.org/10.1039/c4tb01862a.

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5

Wang, Luyan, Xiao Chen, Zhenwen Sun, and Yongcun Chai. "Synthesis of Gold Nanoplates in Lecithin Lamellar Liquid Crystals." Canadian Journal of Chemical Engineering 85, no. 5 (2008): 598–601. http://dx.doi.org/10.1002/cjce.5450850505.

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6

Javed, Ibrahim, Syed Zajif Hussain, Irfan Ullah, et al. "Synthesis, characterization and evaluation of lecithin-based nanocarriers for the enhanced pharmacological and oral pharmacokinetic profile of amphotericin B." Journal of Materials Chemistry B 3, no. 42 (2015): 8359–65. http://dx.doi.org/10.1039/c5tb01258a.

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7

Guang-Yan, HONG, ZHANG Ji-Lin, and GAO Qian. "Synthesis of EuF3 Nanowires in Soybean Lecithin." Acta Physico-Chimica Sinica 26, no. 03 (2010): 695–700. http://dx.doi.org/10.3866/pku.whxb20100312.

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8

Wang, XingGuo, AiYong Qiu, WenYi Tao, and PeiYing Shen. "Synthesis of phosphatidylglycerol from soybean lecithin with immobilized phospholipase D." Journal of the American Oil Chemists' Society 74, no. 2 (1997): 87–91. http://dx.doi.org/10.1007/s11746-997-0149-2.

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9

Li, Sichu, Vijay T. John, Suguna H. Rachakonda, Glen C. Irvin, Gary L. McPherson, and Charles J. O’Connor. "Higher crystallinity superparamagnetic ferrites: Controlled synthesis in lecithin gels and magnetic properties." Journal of Applied Physics 85, no. 8 (1999): 5178–80. http://dx.doi.org/10.1063/1.369116.

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10

Barani, Hossein, Majid Montazer, Nasrin Samadi, and Tayebeh Toliyat. "In situ synthesis of nano silver/lecithin on wool: Enhancing nanoparticles diffusion." Colloids and Surfaces B: Biointerfaces 92 (April 2012): 9–15. http://dx.doi.org/10.1016/j.colsurfb.2011.10.062.

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11

Iwasaki, Tomohiro, and Yuki Yamanaka. "Simple synthesis of layered H-octosilicate in situ surface-modified with lecithin." Applied Clay Science 199 (December 2020): 105866. http://dx.doi.org/10.1016/j.clay.2020.105866.

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12

Cigliano, L., M. Balestrieri, M. S. Spagnuolo, B. Dale, and P. Abrescia. "Lecithin-cholesterol acyltransferase activity during maturation of human preovulatory follicles with different concentrations of ascorbate, a-tocopherol and nitrotyrosine." Reproduction, Fertility and Development 14, no. 1 (2002): 15. http://dx.doi.org/10.1071/rd01044.

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The enzyme lecithin–cholesterol acyltransferase (LCAT) transfers an acyl chain from lecithin to cholesterol or oestradiol, thus playing a crucial role in reverse cholesterol transport and follicular synthesis of potent long-lived oestrogens. The mechanism of catalysis is biphasic, as it is based on a phospholipase and an esterifying activity. Sulfhydryl groups were previously reported to be required for the esterification step. Lecithin–cholesterol acyltransferase has previously been shown to be inhibited by thiol oxidants such as peroxynitrite. Peroxynitrite also converts tyrosine to nitrotyr
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13

Vaziri, N. D., K. Liang, and J. S. Parks. "Acquired lecithin-cholesterol acyltransferase deficiency in nephrotic syndrome." American Journal of Physiology-Renal Physiology 280, no. 5 (2001): F823—F828. http://dx.doi.org/10.1152/ajprenal.2001.280.5.f823.

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Lecithin-cholesterol acetyltransferase (LCAT) is involved in the synthesis of plasma cholesteryl esters and is pivotal in the maturation of plasma high-density lipoprotein (HDL) and conversion of HDL3 to HDL2. In nephrotic syndrome (NS), the ratio of HDL2 to HDL3 is low even though the total concentration of HDL is generally normal. We hypothesize that the reduced HDL2/HDL3 ratio in NS is due to urinary losses of LCAT, leading to plasma LCAT deficiency. To test this hypothesis, Sprague-Dawley rats were randomized to NS (given 130 mg puromycin aminonucleoside on day 1 and 60 mg ip on day 14) or
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14

Sahiner, Nurettin, and Mohit Singh. "In situ micro/nano-hydrogel synthesis from acrylamide derivates with lecithin organogel system." Polymer 48, no. 10 (2007): 2827–34. http://dx.doi.org/10.1016/j.polymer.2007.01.005.

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15

Rosario-Jansen, Theresa, Henry Pownal, Ru-Tai Jiang, and Ming-Daw Tsai. "Phospholipids chiral at phosphorus: Synthesis of dioleoylthiophosphatidylcholine and stereospecificity of lecithin-cholesterol acyltransferase." Bioorganic Chemistry 18, no. 2 (1990): 179–84. http://dx.doi.org/10.1016/0045-2068(90)90040-c.

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16

Moschidis, Michael C. "Synthesis of 1-O-alkylethylene glycol phosphonic acid analogues of lecithin and cephalin." Chemistry and Physics of Lipids 43, no. 1 (1987): 39–45. http://dx.doi.org/10.1016/0009-3084(87)90015-6.

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17

Kennedy, Michael T., Brian A. Korgel, Harold G. Monbouquette, and Joseph A. Zasadzinski. "Cryo-Transmission Electron Microscopy Confirms Controlled Synthesis of Cadmium Sulfide Nanocrystals within Lecithin Vesicles." Chemistry of Materials 10, no. 8 (1998): 2116–19. http://dx.doi.org/10.1021/cm970744k.

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18

Song, Jinliang, Binbin Zhang, Peng Zhang, et al. "Highly efficient synthesis of cyclic carbonates from CO2 and epoxides catalyzed by KI/lecithin." Catalysis Today 183, no. 1 (2012): 130–35. http://dx.doi.org/10.1016/j.cattod.2011.08.042.

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19

Ching-Hong, Chen, Trudy H. Forte, Barbara E. Cahoon, Richard N. Thrift, and John J. Albers. "Synthesis and secretion of lecithin-cholesterol acyltransferase by the human hepatoma cell line HepG2." Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 877, no. 3 (1986): 433–39. http://dx.doi.org/10.1016/0005-2760(86)90209-2.

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20

Jiang, Yang, Jing Du, Honglin Tang, et al. "Synthesis and Application of Nanomagnetic Immobilized Phospholipase C." Journal of Chemistry 2019 (March 3, 2019): 1–9. http://dx.doi.org/10.1155/2019/5951793.

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The nanomagnetic carrier (Fe3O4@SiO2@p(GMA)) was prepared by atom transfer radical polymerization, and then, the free phospholipase C (PLC) was immobilized on it proved by the results of FT-IR analysis. The enzyme loading was 135.64 mg/g, the enzyme activity was 8560.7 U/g, the average particle size was 99.86 ± 0.80 nm, and the specific saturation magnetization was 16.00 ± 0.20 emu/g. PLC-Fe3O4@SiO2@p(GMA) showed the highest activities at the pH of 7.5, and tolerance temperature raised to 65°C in soybean lecithin emulsion. Enzymatic degumming with PLC-Fe3O4@SiO2@p(GMA) under the conditions of
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21

Mok, Amy Y. P., Gordon E. McDougall, and William C. McMurray. "Comparative studies of CDP-diacylglycerol synthase in rat liver mitochondria and microsomes." Biochemistry and Cell Biology 71, no. 3-4 (1993): 183–89. http://dx.doi.org/10.1139/o93-029.

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CDP-diacylglycerol for polyglycerophosphatide biogenesis can be synthesized within rat liver mitochondria. Contamination by microsomal membranes cannot account for the CDP-diacylglycerol synthesis found in the mitochondria. Phosphatidic acid from egg lecithin was the best substrate for the synthesis of CDP-diacylglycerol in both subcellular fractions. Concentration curves for CTP and Mg2+ differed for the two subcellular fractions. Microsomal CDP-diacylglycerol synthase was specifically stimulated by the nucleotide GTP; this stimulatory effect by GTP was not observed in the mitochondrial fract
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22

Fujimoto, Y., H. Uno, C. Kagen, T. Ueno, and T. Fujita. "Effect of diarachidonin on prostaglandin E2 synthesis in rabbit kidney medulla slices." Biochemical Journal 232, no. 3 (1985): 625–28. http://dx.doi.org/10.1042/bj2320625.

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The effect of diarachidonin on the synthesis of prostaglandin E2 in rabbit kidney medulla slices was examined. The addition of diarachidonin stimulated prostaglandin E2 production in a dose-dependent manner. At three concentrations (10, 50 and 100 microM), increases in prostaglandin E2 formation induced by exogenous diarachidonin were 2-fold greater than those induced by exogenous arachidonic acid. Diacylglycerol or phosphatidic acid from egg lecithin had little or no effect on prostaglandin E2 production. Moreover, EGTA failed to inhibit diarachidonin-stimulated prostaglandin E2 formation, in
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23

hosseini, Farzaneh, and Mirabdullah Sadjadi. "Synthesis and Characterization of Soy Lecithin Coated Magnetic Iron Oxide Nanoparticles for Magnetic Resonance Imaging Applications." Oriental Journal of Chemistry 32, no. 6 (2016): 2901–8. http://dx.doi.org/10.13005/ojc/320608.

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24

Azad, Abul Kalam, Abd Almonem Doolaanea, Sinan Mohammed Abdullah Al-Mahmood, John F. Kennedy, Bappaditya Chatterjee, and Hriday Bera. "Electro-hydrodynamic assisted synthesis of lecithin-stabilized peppermint oil-loaded alginate microbeads for intestinal drug delivery." International Journal of Biological Macromolecules 185 (August 2021): 861–75. http://dx.doi.org/10.1016/j.ijbiomac.2021.07.019.

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25

Galvão, Carolina, Luccas Sanches, Beatriz Mathiazzi, Rodrigo Ribeiro, Denise Petri, and Ana Carmona-Ribeiro. "Antimicrobial Coatings from Hybrid Nanoparticles of Biocompatible and Antimicrobial Polymers." International Journal of Molecular Sciences 19, no. 10 (2018): 2965. http://dx.doi.org/10.3390/ijms19102965.

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Hybrid nanoparticles of poly(methylmethacrylate) synthesized in the presence of poly (diallyldimethyl ammonium) chloride by emulsion polymerization exhibited good colloidal stability, physical properties, and antimicrobial activity but their synthesis yielded poor conversion. Here we create antimicrobial coatings from casting and drying of the nanoparticles dispersions onto model surfaces such as those of silicon wafers, glass coverslips, or polystyrene sheets and optimize conversion using additional stabilizers such as cetyltrimethyl ammonium bromide, dioctadecyldimethyl ammonium bromide, or
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26

Abu Ali, Ola A., Mehrez E. El-Naggar, Mohamed S. Abdel-Aziz, Dalia I. Saleh, Mohamed A. Abu-Saied, and Wael A. El-Sayed. "Facile Synthesis of Natural Anise-Based Nanoemulsions and Their Antimicrobial Activity." Polymers 13, no. 12 (2021): 2009. http://dx.doi.org/10.3390/polym13122009.

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Anise oil was prepared in its nanoemulsion form to facilitate the penetration of microbial walls, causing microbe mortality. The penetration occurred easily owing to the reduction in its size (nm). Nanoemulsions with different concentrations of anise oil were prepared using lecithin as an emulsifying agent with the aid of an ultra-sonification process. Their morphological and chemical properties were then characterized. The promising constituents were l-Menthone (11.22%), Gurjunene (6.78%), Geranyl acetate (4.03%), Elemene (3.93%), Geranyl tiglate (3.53%), geraniol (3.48%), linalool (0.17%) as
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27

Jenkins, T. C., and N. Fotouhi. "Effects of lecithin and corn oil on site of digestion, ruminal fermentation and microbial protein synthesis in sheep." Journal of Animal Science 68, no. 2 (1990): 460. http://dx.doi.org/10.2527/1990.682460x.

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28

Kuhn, D. C., and L. M. Demers. "Effect of surfactant on basal and silica-induced eicosanoid production by the alveolar macrophage." American Journal of Physiology-Lung Cellular and Molecular Physiology 269, no. 2 (1995): L165—L170. http://dx.doi.org/10.1152/ajplung.1995.269.2.l165.

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Inflammation and fibrosis subsequent to the inhalation of certain mineral dust particles has been suggested to result from the activation of eicosanoid synthesis by the alveolar macrophage (AM). To determine if surfactant modifies dust-induced generation of eicosanoids by the AM, we evaluated the effect of the surfactant lipid dipalmitoyl lecithin (DPL) on the production of eicosanoids by rat AM exposed to respirable silica dust in vitro. During the first 24-h exposure period, DPL alone significantly increased basal production of eicosanoids but completely inhibited silica-induced thromboxane
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29

Kuzminova, Elena, Marina Semenenko, Evgeny Dolgov, Serik Kanatbaev, and Andrey Abramov. "Pharmacological protection of the detoxification activity of animals’ liver with the help of phospholipid and polysaccharide nature substances complex." E3S Web of Conferences 175 (2020): 03002. http://dx.doi.org/10.1051/e3sconf/202017503002.

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Currently, among chemical pollutants a significant danger to the health of animals and humans represent oxygen-containing nitrogen compounds nitrates and nitrites, which are widely used as mineral fertilizers. The article presents data on the study of chronic nitrate intoxication, reproduced in laboratory animals and its pharmacological correction with a complex of substances of phospholipid and polysaccharide nature. The introduction of sodium nitrate to non-linear rats for 30 days at a dose of 3.8 mg per animal leads to the development of intoxication in rats with dominant signs of liver dam
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30

Galarneau, A., G. Renard, M. Mureseanu, et al. "Synthesis of sponge mesoporous silicas from lecithin/dodecylamine mixed-micelles in ethanol/water media: A route towards efficient biocatalysts." Microporous and Mesoporous Materials 104, no. 1-3 (2007): 103–14. http://dx.doi.org/10.1016/j.micromeso.2007.01.017.

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31

Sangmam, Charles, Jean-Yves Winum, Marc Lucas, Jean-Louis Montero, and Claude Chavis. "A Simple, General and Efficient Method for O and N-Retinoylation. Application to The Synthesis of 2-Retinoyl-Lecithin." Synthetic Communications 28, no. 16 (1998): 2945–58. http://dx.doi.org/10.1080/00397919808004874.

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32

Tsai, M. Y., E. K. Shultz, P. P. Williams, et al. "Assay of disaturated phosphatidylcholine in amniotic fluid as a test of fetal lung maturity: experience with 2000 analyses." Clinical Chemistry 33, no. 9 (1987): 1648–51. http://dx.doi.org/10.1093/clinchem/33.9.1648.

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Abstract We determined concentrations of disaturated phosphatidylcholine (DSPC) in nearly 2000 amniotic fluid samples obtained either transabdominally or as vaginal pools. Here we report our comparison of these DSPC values with the lecithin/sphingomyelin (L/S) ratios for amniotic fluid samples obtained from diabetic and nondiabetic pregnancies and also between transabdominally or vaginally collected samples uncontaminated by blood or meconium. DSPC measurement is at least as good as the L/S ratio in predicting the absence of respiratory distress syndrome. DSPC concentrations were, however, low
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33

Wecker, Lynn. "Neurochemical effects of choline supplementation." Canadian Journal of Physiology and Pharmacology 64, no. 3 (1986): 329–33. http://dx.doi.org/10.1139/y86-054.

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Whether or not the brain can use supplemental choline to enhance the synthesis of acetylcholine (ACh) is an important consideration for assessing the merits of using choline or phosphatidylcholine (lecithin) for the treatment of neuropsychiatric disorders postulated to involve hypocholinergic activity. While it is well documented that administered choline is incorporated into ACh, the ability of supplemental choline to increase the synthesis and release of ACh has been questionable. Studies in my laboratory have demonstrated that acute or chronic choline supplementation does not, by itself, en
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34

SANGMAM, C., J. Y. WINUM, M. LUCAS, J. L. MONTERO, and C. CHAVIS. "ChemInform Abstract: A Simple, General and Efficient Method for O and N-Retinoylation. Application to the Synthesis of 2-Retinoyl-Lecithin." ChemInform 29, no. 49 (2010): no. http://dx.doi.org/10.1002/chin.199849279.

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35

Gylling, Helena, and Tatu A. Miettinen. "Non-cholesterol sterols, absorption and synthesis of cholesterol and apolipoprotein A-I kinetics in a Finnish lecithin-cholesterol acyltransferase deficient family." Atherosclerosis 95, no. 1 (1992): 25–33. http://dx.doi.org/10.1016/0021-9150(92)90172-d.

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36

Albers, John J., Santica M. Marcovnia, and Robert H. Christenson. "Lecithin cholesterol acyltransferase in human cerebrospinal fluid: reduced level in patients with multiple sclerosis and evidence of direct synthesis in the brain." International Journal of Clinical & Laboratory Research 22, no. 1-4 (1992): 169–72. http://dx.doi.org/10.1007/bf02591418.

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37

Chen, Yanfan, Jianghuan Lu, Jie Yang, Kaixuan Hao, and Min Li. "Investigation of Alpha-Fetoprotein Antibody Modified Fluorescent Magnetic Probe on HepG2 Cell and Cancer Model Mouse." Journal of Nanoscience and Nanotechnology 20, no. 8 (2020): 5147–50. http://dx.doi.org/10.1166/jnn.2020.18541.

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To construct a dual-targeting (magnetic targeting and antibody targeting) multi-functional magnetic fluorescent liposome probe with a good biocompatibility and high specificity for early liver cancerdiagnosis. 1,2-distearoyl-sn-glycero-3-phospho-ethanolamine-N-[amino(polyethylene glycol)] (DSPE-PEG2000-NH2) and Cyanine7 N-hydroxysuccinimide ester (Cy7-NHS) were measured and reacted for forming DSPE-PEG2000-Cy7. Egg yolk lecithin, cholesterol, DSPE-PEG2000-Cy7 and Fe3O4 were added in orderly into the reaction solution for synthesis of fluorescent ferroferric oxide (Fe3O4) liposome. The Magnetic
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38

Klimova, E. M., Yu V. Kalashnikova, O. S. Merezhko, and T. I. Kordon. "INDIVIDUAL CORRECTION OF THE TREATMENT OF PATIENTS WITH HEPATOSPLENOMEGALY SYNDROME, TAKING INTO ACCOUNT THE PARAMETERS OF LIPID AND PROTEIN METABOLISM." Kharkiv Surgical School, no. 5-6 (December 14, 2020): 14–21. http://dx.doi.org/10.37699/2308-7005.5-6.2020.03.

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Summary. Purpose: to identify the features of lipid metabolism in patients with hepatosplenomegaly syndrome (HSS) of various origins to develop an individualized approach to the treatment of patients with this pathology.
 Materials and methods: blood serum of 73 patients with HSS on the background of liver cirrhosis complicated by portal hypertension, divided into 3 groups 1) with the etiological factor of hepatitis viruses HCV / HBV, 2) with autoimmune hepatitis with the etiological factor of the herpes group viruses CMV / VEB, 3) against the background of liver hepatosis and fermentopat
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39

Hatahet, Wael, Abdul Soofi, Oyonumo Ntekim, and Thomas Fungwe. "Plasma Lipid Profiles of Transgenic mice expressing the Human ApoB100XCETP are altered differentially by Diets enriched with defined Fatty Acids." Current Research in Nutrition and Food Science Journal 3, no. 3 (2015): 207–18. http://dx.doi.org/10.12944/crnfsj.3.3.04.

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Dietary fat is known to modulate plasma lipid profiles. Synthesis of high density lipoproteins (HDL), which has protective effects on vascular disease is also influenced by dietary fats, but the mechanisms are unclear. The hapoB100XCETP transgenic mouse was used to investigate the effects of fatty acids on the metabolism of plasma lipoproteins, including the pathway leading to synthesis HDL. Male transgenic mice were fed with diets formulated to provide TG (33% energy) as tripalmitin (TP), triolein (TO), tristearin (TS) or equicaloric substitution of fat with carbohydrate (sucrose) for 4 weeks
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40

Dudeja, P. K., T. A. Brasitus, R. Dahiya, M. D. Brown, D. Thomas, and K. Lau. "Intraluminal calcium modulates lipid dynamics of rat intestinal brush-border membranes." American Journal of Physiology-Gastrointestinal and Liver Physiology 252, no. 3 (1987): G398—G403. http://dx.doi.org/10.1152/ajpgi.1987.252.3.g398.

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The present investigations were performed to evaluate whether calcium modulates the physical state and lipid composition of rat enterocyte plasma membranes in vivo. Ca2+ [CaCl2 (50 mM) in NaCl] or NaCl (vehicle control) was administered to rats by intraluminal (gavage) or intraperitoneal routes. Sixty minutes later, brush-border (BBM) and basolateral membranes (BLM) were prepared from the proximal small intestine. By use of the fluorophores, DL-2-(9-anthroyl)-stearic acid (2-AS), DL-12-(9-anthroyl)-stearic acid (12-AS), and 1,6-diphenyl-1,3,5-hexatriene (DPH), steady-state fluorescence polariz
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41

Rafii, Fatemeh, Miseon Park, Amy E. Bryant, Shemedia J. Johnson, and Robert D. Wagner. "Enhanced Production of Phospholipase C and Perfringolysin O (Alpha and Theta Toxins) in a Gatifloxacin-Resistant Strain of Clostridium perfringens." Antimicrobial Agents and Chemotherapy 52, no. 3 (2007): 895–900. http://dx.doi.org/10.1128/aac.01316-07.

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ABSTRACT Clostridium perfringens-induced gas gangrene is mediated by potent extracellular toxins, especially alpha toxin (a phospholipase C [PLC]) and theta toxin (perfringolysin O [PFO], a thiol-activated cytolysin); and antibiotic-induced suppression of toxin synthesis is an important clinical goal. The production of PLC and PFO by a gatifloxacin-induced, fluoroquinolone-resistant mutant strain of C. perfringens, strain 10G, carrying a stable mutation in DNA gyrase was compared with that of the wild-type (WT) parent strain. Zymography (with sheep red blood cell and egg yolk overlays) and tim
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42

Cui, Zhifu, Felix Kwame Amevor, Qian Feng, et al. "Sexual Maturity Promotes Yolk Precursor Synthesis and Follicle Development in Hens via Liver-Blood-Ovary Signal Axis." Animals 10, no. 12 (2020): 2348. http://dx.doi.org/10.3390/ani10122348.

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Several reproductive hormones were reported to be involved in regulating egg yolk precursor synthesis in chickens; however, the mechanism that shows how the liver-blood-ovary signal axis works in relation to age changes has not been reported yet. Therefore, in this study, we observe the morphology and histology of the liver and ovary and determine the serum biochemical parameters and the expression abundance of the critical genes from d90 to 153. Results show that the body weight and liver weight were significantly increased from d132, while the ovary weight increased from d139. Aside from the
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43

Bursten, S. L., W. E. Harris, K. Resch, and D. H. Lovett. "Lipid A activation of glomerular mesangial cells: mimicry of the bioactive lipid, phosphatidic acid." American Journal of Physiology-Cell Physiology 262, no. 2 (1992): C328—C338. http://dx.doi.org/10.1152/ajpcell.1992.262.2.c328.

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Lipid A, the active component of bacterial endotoxin, stimulates multiple cell types, including glomerular mesangial cells (MC), and yet the molecular mechanisms of cell activation remain unclear. Lipid A, in its monosaccharyl form, structurally resembles the biologically active lipid phosphatidic acid (PA). Given this, it was postulated that lipid A activates cells by acting as a structural and functional mimetic of PA. Lipid A was found to specifically stimulate an MC lyso-PA acyl transferase activity, leading to enhanced synthesis of sn-2-unsaturated forms of PA. Sn-2-unsaturated PA itself,
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Baldi, A., and L. Pinotti. "Choline metabolism in high-producing dairy cows: Metabolic and nutritional basis." Canadian Journal of Animal Science 86, no. 2 (2006): 207–12. http://dx.doi.org/10.4141/a05-061.

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Choline, the beta-hydroxyethyltrimethylammonium ion, is a strong base containing a trimethylated quaternary nitrogen. Choline occurs widely in biological materials as the compound itself, as acetylcholine and as various phospholipids. In feed ingredients and crude unprocessed fat sources, most choline is present as phosphatidylcholine (lecithin). Although soybean, soybean meal, rapeseed meal, fish meal and dried yeast are relatively rich sources of choline, the bioavailability of choline in these feedstuffs is only moderate. In dairy ruminants, choline is extensively degraded in the rumen. For
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Moran, Paula, and Brian E. Leonard. "Noradrenaline and animal cognitive processes: implications for dementia." Irish Journal of Psychological Medicine 6, no. 2 (1989): 106–8. http://dx.doi.org/10.1017/s079096670001541x.

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AbstractRecent research on the neurochemical deficits that accompany Alzheimer's disease (AD), senile dementia (SD) and Korsakoff's dementia (KD) have prompted renewed interest in the involvement of central cholinergic systems in learning and memory processes. Evidence for the role of cholinergic systems in the dementias is now overwhelming and has been reviewed in detail elsewhere, e.g. Briefly, such evidence includes findings of decreased cortical activity of the cholinergic marker enzyme choline-acetyltransferase (CAT), reduced activity of the acetylcholine degrading enzyme acetylcholineste
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Elkhoury, Kamil, Laura Sanchez-Gonzalez, Pedro Lavrador, et al. "Gelatin Methacryloyl (GelMA) Nanocomposite Hydrogels Embedding Bioactive Naringin Liposomes." Polymers 12, no. 12 (2020): 2944. http://dx.doi.org/10.3390/polym12122944.

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The development of nanocomposite hydrogels that take advantage of hierarchic building blocks is gaining increased attention due to their added functionality and numerous biomedical applications. Gathering on the unique properties of these platforms, herein we report the synthesis of bioactive nanocomposite hydrogels comprising naringin-loaded salmon-derived lecithin nanosized liposomal building blocks and gelatin methacryloyl (GelMA) macro-sized hydrogels for their embedding. This platform takes advantage of liposomes’ significant drug loading capacity and their role in hydrogel network reinfo
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Sanarova, E. V., A. V. Lantsova, Xi Zhang, et al. "DEVELOPING A MODEL OF LIPOSOMAL FORMULATION OF A NEW NATIONAL ANALOGUE HYPOTHALAMIC HORMONE SOMATOSTATIN, WHICH HAS ANTI-TUMOR ACTIVITY." Russian Journal of Biotherapy 14, no. 4 (2015): 73–78. http://dx.doi.org/10.17650/1726-9784-2015-14-4-73-78.

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At present, the hormone somatostatin analogues is increasing interest in connection with their activity against hormone-dependent tumors, which leads to the need to develop domestic drugs belonging to this group. In the laboratory of chemical synthesis Institute of experimental diagnostics and chemotherapy of FSBI «N.N. Blokhin RCRC» synthesized new domestic pentapeptide somatostatin analogue of hypothalamic hormone (AGGS). In preliminary studies of this substance demonstrated sufficiently high antitumor activity AGGS on transplanted solid tumors of mice. Due to the insolubility of the substan
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Ribeiro, Rodrigo Tadeu, Carolina Nascimento Galvão, Yunys Pérez Betancourt, Beatriz Ideriha Mathiazzi, and Ana Maria Carmona-Ribeiro. "Microbicidal Dispersions and Coatings from Hybrid Nanoparticles of Poly (Methyl Methacrylate), Poly (Diallyl Dimethyl Ammonium) Chloride, Lipids, and Surfactants." International Journal of Molecular Sciences 20, no. 24 (2019): 6150. http://dx.doi.org/10.3390/ijms20246150.

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Hybrid and antimicrobial nanoparticles (NPs) of poly (methyl methacrylate) (PMMA) in the presence of poly (diallyl dimethyl ammonium) chloride (PDDA) were previously obtained by emulsion polymerization in absence of surfactant with low conversion. In the presence of amphiphiles such as cetyl trimethyl ammonium bromide (CTAB), dioctadecyl dimethyl ammonium bromide (DODAB) or soybean lecithin, we found that conversion increased substantially. In this work, the effect of the amphiphiles on the NPs core-shell structure and on the antimicrobial activity of the NPs was evaluated. NPs dispersions cas
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Tarantino, Germano, Elisa Brilli, Ylenia Zambito, Giulio Giordano, and Francesco Equitani. "Sucrosomial Iron®: A New Highly Bioavaible Oral Iron Supplement." Blood 126, no. 23 (2015): 4561. http://dx.doi.org/10.1182/blood.v126.23.4561.4561.

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Abstract Introduction: Iron deficiency is one of the most widespread nutritional deficiencies. Globally two billion people are suffering from iron- deficiency anemia (Hermida et al., 2010). Oral therapy for iron deficiency is mainly based on immediate release formulations of ferrous iron. However, modified formulations have been marketed to reduce gastrointestinal side effects and to prevent iron instability in the gastrointestinal tract. Overcoming biological barriers, including the gastrointestinal epithelial barriers, is a great challenge for pharmaceutical research and thus there is a need
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Holopura, S. I., M. I. Tsvilikhovsky, and B. V. Popadiuk. "Influence of medication “Membranostabil” on expression of immunoreceptor proteins in small intestine of ruminants during the period of formation of colostral immunity." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 21, no. 96 (2019): 147–52. http://dx.doi.org/10.32718/nvlvet9626.

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The influence of medication “Membranostabil” on the indexes of content of proteins with MM of 33, 40, and 47 kDa in the plasmolemma of enterocytes of jejunum of new-born calves during the period from birth till the age of 24-hours was investigated. The research was conducted on calves (males) of Ukrainian black-and-white breed during the spring. Throughout the trial period, the calves of the control and experimental groups were kept on a standard diet for newborn calves, colostrum. In addition, calves of the experimental group got the medication “Membranostabil” based on the soybean lecithin.
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