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Dissertations / Theses on the topic 'Lecithins'

Author: Grafiati

Published: 4 June 2021

Last updated: 30 January 2023

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1

Malik, Shagufta. "The behaviour of surfactants in nonaqueous media." Thesis, University of Nottingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299582.

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2

Heift, Claudia. "Zusammensetzung und Funktionalität des Lecithins aus Rapssaaten für erweiterte Anwendungen im Lebensmittelbereich." [S.l.] : [s.n.], 2007. http://deposit.ddb.de/cgi-bin/dokserv?idn=984535756.

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3

Mackie, Andrew C. "Lecithin-stabilised silica dispersions in non-aqueous media." Thesis, University of Nottingham, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236022.

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4

Wettstein, Hans-Rudolf. "Influence of plant lecithins on rumen fermentation, lipid digestion and quality of milk and body fat in cattle /." [S.l.] : [s.n.], 2000. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=13721.

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5

Soares, Marinalda da Silva. "Processamento de oleo de soja utilizando ultrafiltração em miscela na etapa de degomagem e na obtenção de lecitina." [s.n.], 2004. http://repositorio.unicamp.br/jspui/handle/REPOSIP/254701.

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Orientadores: Lireny Aparecida Guaraldo Gonçalves, Luiz Antonio Viotto<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia de Alimentos<br>Made available in DSpace on 2018-08-03T21:14:27Z (GMT). No. of bitstreams: 1 Soares_MarinaldadaSilva_D.pdf: 1635248 bytes, checksum: f576efc88ef55b05d1817c84d8468ee7 (MD5) Previous issue date: 2004<br>Resumo: Tradicionalmente o óleo de soja bruto é degomado por adição de água ou solução ácida. A tecnologia de membranas aplicada ao processamento de óleos vegetais tem se tornado importante, pois utiliza baixas temperaturas, não

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6

Fernandes, Gabriel Deschamps 1988. "Caracterização de lecitinas comerciais por espectrometria de massas ambiente com ionização sonic-spray." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/256072.

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Orientador: Daniel Barrera Arellano<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia de Alimentos<br>Made available in DSpace on 2018-08-19T21:15:47Z (GMT). No. of bitstreams: 1 Fernandes_GabrielDeschamps_M.pdf: 1854677 bytes, checksum: e57833484e8f9ad4a136187bed59d8d2 (MD5) Previous issue date: 2012<br>Resumo: Os fosfolipídios são definidos como o grupo de moléculas que contém um grupamento fosfato. Por apresentarem características anfipáticas, este grupo de moléculas se organiza naturalmente em bicamadas, originando as membranas dos seres vivos. Indust

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7

Svensson, B. Martin. "Lipase catalysis in lecithin-stabilised microemulsions." Thesis, University of East Anglia, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406836.

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8

Beattie, Stuart Gavin. "Lecithin colesterol ACYL transferase gene transfer studies." Thesis, Royal Holloway, University of London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409233.

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9

Ghazi, Samira. "Factors influencing expression of lecithin : cholesterol acyltransferase." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322763.

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10

Chamberlin, Richard Addison. "Light scattering studies on lecithin micellar solution." Thesis, Massachusetts Institute of Technology, 1991. http://hdl.handle.net/1721.1/13859.

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11

Viñado, Martínez Alberto. "Use of soybean lecithin in broiler chicken diets." Doctoral thesis, Universitat Autònoma de Barcelona, 2019. http://hdl.handle.net/10803/667795.

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La adición de grasas es una práctica habitual en la fabricación de piensos para avicultura, ya que son fuente de energía y ácidos grasos esenciales. La disponibilidad de ingredientes con alto contenido energético se puede ver reducida a causa del aumento de población mundial y la utilización de aceites vegetales para la producción de biodiesel. Por ello, la lecitina de soja (L), un coproducto del refinado del aceite de soja (S), puede ser una fuente de energía alternativa, ya que presenta un alto contenido en fosfolípidos, triacilgliceroles, ácidos grasos libres (AGL), fósforo, colina y compue

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12

Alsaab, Hashem O. "Evaluation of the Percutaneous Absorption of Chlorpromazine Hydrochloride from PLO Gels Across Porcine Ear and Human Abdominal Skin." University of Toledo Health Science Campus / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=mco1435670713.

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13

Low, J. K. "Protein and cell therapy for lecithin-cholesterol acyltransferase (LCAT) deficiency." Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/14474/.

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Lecithin-cholesterol acyltransferase (LCAT) is an enzyme principally secreted by the liver into the circulation where it esterifies cholesterol and plays a key role in high- density lipoprotein (HDL) metabolism. In familial and acquired (liver disease) LCAT deficiency, the failure to esterify cholesterol causes many cellular and metabolic disturbances. Here, I describe the purification of recombinant LCAT and assess two approaches to treat LCAT deficiency. Human LCAT cDNA was cloned into a selectable expression vector and used to generate a stably–transfected Chinese hamster ovary (CHO) cells

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14

Lucht, Julie. "Viscosity Characterization of 20% Pluronic Lecithin Organogel at varying pHs." The University of Arizona, 2009. http://hdl.handle.net/10150/623980.

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Class of 2009 Abstract<br>OBJECTIVES: The primary objective of this experiment was to characterize the pH stability range of 20% Pluronic lecithin organogel (PLO). We intended to determine the viscosity at varying pHs. We prepared six samples of 20% PLO. METHODS: An initial rheological reading of each sample was recorded by a dynamic stress rheometer. Each sample was titrated drop-wise with citric acid or KOH in 0.5 pH increments. When the desired pH was obtained, a 0.5 mL sample was analyzed with a dynamic stress rheometer, RS-200, using Rheos software. RESULTS: Since PLO is a non-Newtonian

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15

Taylor, Lynn Elizabeth. "Acid-base regulation during sprint exercise in horses fed lecithin." Diss., This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-06062008-163251/.

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16

Cavaco, Carolina Cavaco M. Carolina. "Structural and dynamic properties of giant polymer-like lecithin reverse micelles /." [S.l.] : [s.n.], 1994. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=10897.

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17

Svensson, Dag. "Creating High Fat Emulsions with Mango, Rapeseed Oil and Soy Lecithin." Thesis, Linnéuniversitetet, Institutionen för naturvetenskap, NV, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-24084.

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Food inevitably plays a vital role in our lives and is of great importance to our health and wellbeing. With increasing age, it is equally important to achieve adequate nutrition to prevent and alleviate age-related diseases. One problem is that far too many older adults find it difficult to eat enough nutritious food which in the long term may lead to malnutrition. With an increasing life expectancy the older population is growing and the problem with malnutrition is of great concern. Malnutrition can be caused by many different factors which make it difficult to find a single unique solution

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18

Kotzian, Roland. "Removal of metal ions from aqueous solutions using lecithin enhanced ultrafiltration." Thesis, Loughborough University, 1998. https://dspace.lboro.ac.uk/2134/15378.

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This work is concerned with an alternative method for metal ion removal from aqueous solutions - surfactant enhanced ultrafiltration. Surfactant monomers aggregate above a certain concentration, specific to the surfactant, to form micelles. Anionic surfactant micelles will attract and bind metal cations. Free metal ions and surfactant monomers pass freely through an ultrafiltration membrane, but if the micelle-metal ion complex is sufficiently large it is rejected. Research reported in this thesis has been carried out on well defined aqueous solutions containing only one type of metal ion toge

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19

Yip, Shiu Hang. "Supercritical Fluid Extraction and Chromatography of Various Lipids from Soybean Lecithin." Thesis, Virginia Tech, 2007. http://hdl.handle.net/10919/35349.

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Phospholipids are commonly found in biological membranes. They have a polar head group and two ester linked fatty acids tails. Different methods such as thin layer chromatography and high performance liquid chromatography coupled with ultraviolet, refractive index, flame ionization detector, and mass spectrometry (MS) detection have long been used in the study of phospholipids. These methods were time-consuming and lacked quantitative accuracy. In this work, phosphatidylcholine, phosphatidyl-ethanolamine, phosphatidylinositol and phosphatidylserine have been studied by supercritical fluid chro

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20

Corswant, Christian von. "Lecithin-based microemulsions for pharmaceutical use phase behavior and solution structure /." Lund : Lund University, 1998. http://catalog.hathitrust.org/api/volumes/oclc/68945035.html.

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21

Sperber, Galia. "Attempts to generate atheroprotective lecithin-cholesterol acyltransferase (LCAT) phenotypes by chimeraplasty." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1446120/.

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Lecithin-cholesterol acyltransferase (LCAT) is a high-density lipoprotein (HDL)-associated enzyme, which is secreted mainly by the liver. By esterifying cholesterol in the surface of immature HDL, LCAT drives reverse cholesterol transport, an important process in preventing atherosclerosis. Specific point mutations in the LCAT gene, producing serine to alanine amino acid substitutions at positions 208 or 216, are reported to increase enzymatic activity up to 14 times. Here, I attempt to create these mutations using a new technology, termed chimeraplasty targeted gene repair in situ using synth

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22

Ayres, Benjamin Robert. "Use of Soybean Lecithin in Shape Controlled Synthesis of Gold Nanoparticles." PDXScholar, 2013. https://pdxscholar.library.pdx.edu/open_access_etds/628.

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The work presented in this dissertation is a composite of experiments in the growth of gold nanoparticles with specific optical properties of interest. The goal is to synthesize these gold nanoparticles using soybean extract for not only shape control, but for propensity as a biocompatible delivery system. The optical properties of these nanoparticles has found great application in coloring glass during the Roman empire and, over the centuries, has grown into its own research field in applications of nanoparticulate materials. Many of the current functions include use in biological systems as

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23

Arnold, Gunther. "Wirkungsbeziehungen von Lecithinen und Phospholipiden in ölbasierten Systemen." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-154174.

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Lecithin wird unter anderem zur Steuerung der rheologischen Eigenschaften von Lebensmittelsuspensionen wie zum Beispiel Schokolade eingesetzt. In erster Linie findet dabei Sojalecithin Verwendung, wogegen die Wirkungen von Lecithinen aus Sonnenblumen oder Raps unzureichend dokumentiert sind. Anhand von Untersuchungen an Modellsuspensionen werden Wirkungsbeziehungen von Lecithin auf mikrostruktureller Ebene beleuchtet, um Ursachen für dessen Funktionalität in ölbasierten Suspensionen abzuleiten. Darüber hinaus erfolgt ein Vergleich der Wirkung von Soja-, Raps- und Sonnenblumenlecithin auf rheol

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24

Yao, Zemin. "Isolation of rat liver CTP: phosphocholine cytidylyltransferase and regulation of hepatic phosphatidylcholine biosynthesis." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/25073.

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Two kinds of affinity chromatography, CDP-choline- and CTP-Sepharose 4B, were investigated for purification of the cytosolic CTP:phosphocholine cytidylyltransferase from rat liver. The enzyme did not show strong affinity for the CDP-choline Sepharose resin, but bound to the CTP-Sepharose column in the presence of 14 mM magnesium acetate. The combination of CTP affinity chromatography with ion-exchange techniques provided about 70-fold purification of the cytosolic enzyme with a specific activity of about 90 units per milligram protein. The influence of diphenylsulfone compounds on the synthe

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25

Castejon, Letícia Vieira. "Parâmetros de qualidade na clarificação da lecitina de soja." Universidade Federal de Uberlândia, 2015. https://repositorio.ufu.br/handle/123456789/17770.

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A lecitina de soja é um complexo de fosfolipídeos em óleo de soja, sendo denominada de lecitina de soja comercial. Sua coloração é âmbar, apresenta alta viscosidade, cheiro e gosto característicos. É bastante utilizada como emulsificante, possui características próprias devido a modificações física, químicas ou de processos de obtenção. O presente trabalho teve por objetivo avaliar fisico-quimicamente lecitinas de soja clarificadas, pela adição de peróxido de hidrogênio a 35% (v/v), a temperatura e agitação controladas. Avaliar os aspectos qualitativos e de coloração, para posterior aplicação

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26

Holland, Janice Lee. "Lecithin containing diets for the horse: acceptance, digestibility, and effects on behavior." Thesis, Virginia Tech, 1994. http://hdl.handle.net/10919/30978.

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Lecithins may improve the digestibility of high fat diets and the tractability of horses. Experiments were conducted to determine the acceptability, digestibility and effects on behavior of lecithin-containing diets. Seven young horses of light breeds were used for the studies. The four concentrates consisted of corn, oats, beet pulp, trace mineralized salt, dried sugar cane molasses plus 10% added fat: corn oil (CO);soy lecithin-corn oil (SL\CO); soy lecithin-soybean oil (SL\SO); or soy lecithin-corn oil-soybean oil (SL\CO\SO). Half the ration was provided by chopped hay. The CO concentrat

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27

Cooke, Allison L. B. A. "The Molecular Interaction of Apolipoprotein A-I and Lecithin: Cholesterol Acyl Transferase." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1543580636448357.

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28

Wilson, Judith A. "Sarcoplasmic reticulum responses to repeated sprints, conditioning and dietary lecithin in the horse." Diss., This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-06062008-163309/.

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29

Henley, Cheryl Lynn. "Ã-naphthylisothiocyanate induced cholestasis with secondary lecithin, cholesterol acyltransferase deficiency in C57BL/6 mice." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ36465.pdf.

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30

Hodgson, Isaac Owusu Afriyie. "Removal of lead, copper and cadmium ions from aqueous streams using lecithin enhanced microfiltration." Thesis, Loughborough University, 2003. https://dspace.lboro.ac.uk/2134/12130.

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The removal of lead, copper and cadmium ions from aqueous streams using lecithin enhanced micro filtration with 0.2μm pore size tubular ceramic membranes has been investigated. Measurements of the surface tension at varying lecithin concentrations were carried out to determine the critical micelle concentration (CMC) of lecithin and the effects of lead ions, mixtures of lead and copper ions, and mixtures of lead, copper and cadmium ions in solutions on the CMC of lecithin. The zeta potential and the effects of the single and multiple metal ions on the zeta potential of lecithin were also inves

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31

Bonam, Sindhu Prabha. "Preparation and Evaluation of Pluronic Lecithin Organogel Containing Ricinoleic acid for Transdermal Drug Delivery." University of Toledo Health Science Campus / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=mco1384437353.

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32

Weddle, Carolyn A. "Optimization of HPLC techniques for separation of oxidized phosphatidylcholines." Virtual Press, 2005. http://liblink.bsu.edu/uhtbin/catkey/1319835.

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In cellular studies of patients with lipid related disorders such as mammary cancers, leukemia, and artheroscierosis, separation of molecular species of oxidized phosphatidylcholine (PC) can be an important assistance in research or diagnosis. Goals of this project were to optimize separation of oxidized and unoxidized PC molecular species in a single HPLC chromatogram followed by in line identification of hydroperoxides. Oxidized egg PC's were produced using UV light exposure in air. Separations were performed on an Ultrasphere ODS column and an Asahipak ODPVA column using a Waters 2695 syste

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33

Simard, Gilles. "Dynamique intra-vasculaire des lipoproteines de haute densite ; role des enzymes lipolytiques." Toulouse 3, 1990. http://www.theses.fr/1990TOU35001.

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34

Séguret, Mace Sandrine. "Role de la lecithine cholesterol acyltransferase dans le metabolisme des lipoproteines de haute densite (hdl) : application a la therapie genique du deficit en hdl." Paris 11, 1997. http://www.theses.fr/1997PA114808.

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35

Davit-Spraul, Anne. "Dyslipoproteinemie du syndrome d'alagille : capacites fonctionnelles des lipoproteines de haute densite (hdl) et activite lecithine : cholesterol acyl tranferase." Paris 11, 1997. http://www.theses.fr/1997PA114839.

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36

Parekh, Khushboo K. "Preparation, Characterization, and In Vitro Protein Release Studies in Pharmaceutically relevant Lecithin Microemulsions." University of Toledo Health Science Campus / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=mco1300753350.

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37

St, Clair Caryn M. "Neonatal Respiratory Distress Syndrome as a Function of Gestational Age and the Lecithin/Sphingomyelin Ratio." [New Haven, Conn. : s.n.], 2007. http://ymtdl.med.yale.edu/theses/available/etd-08272007-123115/.

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38

Madenci, Dilek. "Study of the aggregation behaviour of egg yolk lecithin/bile salt mixtures by increasing the ionic strength." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/4918.

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This thesis describes a study of the aggregational behaviour of egg yolk lecithin (EYL), a natural lecithin, and bile salt mixtures especially with respect to an increase of the ionic strength of the solvent. Mixtures of two amphiphiles with very different spontaneous curvature as EYL lecithin and bile salt form mixed micelles and vesicles in aqueous solution. Their properties have been well-studied under physiological conditions, i.e. 150 mM electrolyte concentration and pH 7- 8, while other conditions are still hardly explored. Upon increasing ionic strength the formed structures and the tra

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39

GENAY, PATRICK. "Asthme professionnel du boulanger : a propos de deux cas d'allergie respiratoire a la lecithine de soja." Reims, 1992. http://www.theses.fr/1992REIMM007.

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40

Ayyobi, Amir Fardad. "Analysis of lecithin : cholesterol acyltransferase (LCAT) protein structure and its influence on binding to plasma lipoproteins." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0014/NQ56499.pdf.

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41

Wang, Guang. "Functionality of egg yolk lecithin and protein and functionality enhancement of protein by controlled enzymatic hydrolysis." [Ames, Iowa : Iowa State University], 2007.

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42

Kline, Kristen Alissa. "Metabolic effects of incremental exercise on Arabian horses fed diets containing corn oil and soy lecithin." Thesis, Virginia Tech, 1997. http://hdl.handle.net/10919/37030.

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Feeding a fat-containing diet to the exercising horse is a facile way to increase energy density without risking the complications associated with hydrolyzable carbohydrates. Fat adaptation may also result in increases in the utilization of free fatty acids for fuel during exercise and sparing of muscle glycogen. Phosphatidylcholine, the main component of lecithins, can influence muscle contraction and improve endurance capacity during exercise. When it is combined with corn oil in a total mixed ration, soy lecithin is both highly digestible and palatable to horses. Our objectives in this

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43

Andrade, Valléria Matos. "Obtenção de gel PLO contendo rutina para aplicação transdérmica : caracterização, estabilidade e atividade antioxidante." Pós-Graduação em Ciências Farmacêuticas, 2017. http://ri.ufs.br/jspui/handle/riufs/7785.

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Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPq<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>Rutin is a flavonoid widely reported in the literature for its antioxidant properties, anti-inflammatory, vasoprotective, antithrombogen, among others. However, its low solubility in aqueous media reduces its bioavailability orally and, therefore, transdermal administration proves to be promising. Thus, the present work aimed to obtain, characterize and evaluate an activity and antioxidant activity of a gel. PLO (Pluronic Lecithin Organogel)

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44

Crespilho, André Maciel [UNESP]. "Estudo comparativo de diferentes metodologiasde preservação do sêmen bovino para a utilização e programas de inseminação artificial em tempo-fixo(IATF)." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/105905.

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Made available in DSpace on 2014-06-11T19:35:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-08-26Bitstream added on 2014-06-13T20:46:11Z : No. of bitstreams: 1 crespilho_am_dr_botffmvz.pdf: 1224891 bytes, checksum: 5f6cd3bb0ea028b0690772b9a9bf8493 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>O objetivo do estudo foi comparar a efetividade de três diluidores empregados para criopreservação e refrigeração do sêmen bovino em relação aos padrões de motilidade, integridade de membrana plasmática e acrossomal, índice de peroxidação lipídica e fertilidade nos

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45

Tantipolphan, Ruedeeporn, and n/a. "Characterisation of protein-phospholipid interactions in implantable delivery systems." University of Otago. School of Pharmacy, 2007. http://adt.otago.ac.nz./public/adt-NZDU20071218.162425.

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Purpose: This thesis aimed to gain a better understanding of the effects of salts in modifying in vitro phase behaviour of lecithin and cholesterol solid implants and to obtain further information on in vitro protein release and stability. Methods: Raman spectroscopy and partial least squares regression (PLSR) were used to investigate lecithin-cholesterol molecular interactions as a function of method of preparation. Lipid-salt interactions were studied by attenuated total reflectance Fourier transform infrared (ATR-FTIR) and Raman spectroscopy using principal component analysis (PCA). In vi

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46

Stroppa, Valter Luís Zuliani. "Influência de lecitina e PGPR no processo de microestruturação de chocolate amargo." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/266882.

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Orientadores: Lireny Aparecida Guaraldo Gonçalves, Priscila Efraim<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Química<br>Made available in DSpace on 2018-08-18T18:52:26Z (GMT). No. of bitstreams: 1 Stroppa_ValterLuisZuliani_M.pdf: 1829992 bytes, checksum: 1eb19d94141314569616332614683d54 (MD5) Previous issue date: 2011<br>Resumo: Chocolates são produtos compostos por uma fase lipídica com predominância de manteiga de cacau, e que contem liquor, açúcar emulsificantes e eventualmente leite em pó (ou derivados lácteos) e aromas. As características fís

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47

Li, Min. "Site-directed mutagenesis of the branchpoint sequence of intron 4 of the human lecithin : cholesterol acyltransferase gene." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0019/NQ56575.pdf.

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48

Saint-Pierre-Chazalet, Michèle. "Structure et interactions en mono et multicouches de cyanine a longues chaines et d'amphotericine b." Paris 6, 1987. http://www.theses.fr/1987PA066208.

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49

Park, Yong Bok. "Studies on Hog Plasma Lecithin:cholesterol Acyltransferase: Isolation and Characterization of the Enzyme." Thesis, North Texas State University, 1987. https://digital.library.unt.edu/ark:/67531/metadc331699/.

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Lecithin:cholesterol acyltransferase (LCAT) was isolated from hog plasma and basic physicochemical properties and functionally important regions were investigated. Approximately one milligram of the enzyme was purified to apparent homogeneity with approximately a 20,000-fold increase in specific activity. In the plasma, hog LCAT was found to associate with high-density lipoproteins (HDL) probably through hydrophobic interactions with apolipoprotein A-I. HDL was the preferred lipoprotein substrate of the enzyme as its macromolecular substrate. The enzyme was found to contain 4 free sulfhydryl g

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Yao, Zemin. "Phosphatidylcholine biosynthesis and lipoprotein secretion in rat hepatocytes." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/29220.

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Abstract:

Young male rats fed a choline-deficient diet for three days accumulated triacylglycerol (TG) in the liver, and had reduced very low density lipoprotein (VLDL), but not high density lipoprotein (HDL), levels in the plasma. Cultured hepatocytes obtained from these rats were used as a model system to investigate how choline deficiency affected hepatic lipogenesis, apolipoprotein synthesis and lipoprotein secretion. When the cells were cultured in a medium free of choline and methionine, the secretion of TG and phosphatidylcholine (PC) was impaired. Supplementation of choline, methionine or lysoph

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