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Dissertations / Theses on the topic 'Lectins'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Lucca, Rosemeire Aparecida da Silva de. "Propriedades físico-químicas da lectina KM+ monitoradas por dicroismo circular (CD) e fluorescência. Estimativa do conteúdo de estrutura secundaria por CD." Universidade de São Paulo, 1994. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-02042014-100315/.

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Uma nova lectina extraída da semente de Artocarpus integrifólia, denominada KM+ foi recentemente descrita. KM+ e haptotática para neutrófilos, promove a aglutinação de hemácias dos grupos A, B, 0, estimula a proliferação de linfócitos do baço de camundongos e liga-se em &#945 D-manose, &#945 metil manosidio e &#945 D-glicose. Esta lectina é composta por quatro monômeros, com peso molecular de 13.150 daltons cada, unidos por interações não covalentes. KM+ contem 1,8% de carboidratos e apresentou quatro isoformas com pontos isoelétricos entre 4,2 e 5,2. Este trabalho teve como objetivos estudar

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2

Silva, Luana Maria Castelo Melo. "Efeito da lectina da alga marinha vermelha Pterocladiella capillace em feridas limpas induzidas em ratos." reponame:Repositório Institucional da UFC, 2012. http://www.repositorio.ufc.br/handle/riufc/18834.

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SILVA, Luana Maria Castelo Melo. Efeito da lectina da alga marinha vermelha Pterocladiella capillace em feridas limpas induzidas em ratos. 2012. 135 f. Tese (Doutorado em bioquímica)- Universidade Federal do Ceará, Fortaleza-CE, 2012.<br>Submitted by Elineudson Ribeiro (elineudsonr@gmail.com) on 2016-07-20T16:16:36Z No. of bitstreams: 1 2012_tese_lmcmsilva.pdf: 10225620 bytes, checksum: 67dadb7130fbee0f6137beb9f3cec43e (MD5)<br>Approved for entry into archive by José Jairo Viana de Sousa (jairo@ufc.br) on 2016-08-02T18:10:12Z (GMT) No. of bitstreams: 1 2012_tese_lmcmsilva.pdf: 10225620 byte

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Oliveira, Wilian Rosário de. "Lectinas de Crotalaria spectabilis R.: isolamento, purificação e atividade aglutinante em Leptospira biflexa (saprófita) e L. interrogans (patogênica)." Instituto de Ciências da Saúde, 2014. http://repositorio.ufba.br/ri/handle/ri/23507.

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Submitted by Programa de Pós-graduação em Biotecnologia (mebiotec.ufba@gmail.com) on 2017-04-04T13:24:02Z No. of bitstreams: 1 Dissertação Final- WILIAN OLIVEIRA.pdf: 1510952 bytes, checksum: 9058b21042c585177d09b07cc902395e (MD5)<br>Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2017-07-06T12:57:28Z (GMT) No. of bitstreams: 1 Dissertação Final- WILIAN OLIVEIRA.pdf: 1510952 bytes, checksum: 9058b21042c585177d09b07cc902395e (MD5)<br>Made available in DSpace on 2017-07-06T12:57:28Z (GMT). No. of bitstreams: 1 Dissertação Final- WILIAN OLIVEIRA.pdf: 1510952 bytes, checksum: 90

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Bibi, Rashda. "Synthèse de nouveaux dérivés osidiques pour le ciblage de lectines originales." Thesis, Montpellier, Ecole nationale supérieure de chimie, 2012. http://www.theses.fr/2012ENCM0002.

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Les lectines spécifiques du rhamnose ont été découvertes comme nouvelle classe de lectines dans les années 1990. La plupart de ces lectines a été isolée à partir d'animaux aquatiques. Des récepteurs spécifiques du rhamnose sur les kératinocytes ont été découverts en 1991 quand les reconnaissances entre des glycoprotéines synthétiques incorporées dans des liposomes et des kératinocytes ont été étudiées. Nous avons synthétisé des nouveaux dérivés de rhamnose à cibler ces lectines<br>Rhamnose binding lectines were discovered as new class of lectines in 1990's. Most of these lectines has been isol

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5

Santos, Adriano dos [UNESP]. "Estudo da afinidade das proteínas rTgMIC1 e rTgMIC4 da Toxoplasma gondii com fetuína e asialofetuína utilizando técnica piezelétrica." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/92055.

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Made available in DSpace on 2014-06-11T19:25:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-05-08Bitstream added on 2014-06-13T18:29:02Z : No. of bitstreams: 1 santos_a_me_araiq.pdf: 1458862 bytes, checksum: f7fe58d688854cba187d0f1e30f22ce7 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>As proteínas de micronema TgMIC1 e TgMIC4 (TgMICs) da Toxoplasma gondii fazem parte de um complexo proteico localizado na superfície do parasita responsável pelo processo de adesão e invasão celular. O

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Santos, Adriano dos. "Estudo da afinidade das proteínas "rTgMIC1" e "rTgMIC4" da Toxoplasma gondii com fetuína e asialofetuína utilizando técnica piezelétrica /." Araraquara : [s.n.], 2012. http://hdl.handle.net/11449/92055.

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Orientador: Paulo Roberto Bueno<br>Banca: Emanuel Carrilho<br>Banca: Maria Cristina Roque Antunes Barreira<br>Resumo: As proteínas de micronema TgMIC1 e TgMIC4 (TgMICs) da Toxoplasma gondii fazem parte de um complexo proteico localizado na superfície do parasita responsável pelo processo de adesão e invasão celular. Os objetivos desse trabalho foram estudar dispositivos piezelétricos contendo em cada um, uma das MICs recombinantes (rTgMIC1 ou rTgMIC4) e utilizá‐los na determinação das constantes de afinidade entre elas com a fetuína e asialofetuína, empregando o modelo da Isoterma de Langmuir.

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7

Destecroix, Harry. "Anthracene based synthetic lectins." Thesis, University of Bristol, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.682557.

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Over the past 40 years there has been substantial interest in continuous glucose monitors (CGMs) for diabetes management. Much of the work has focused on the use of enzymes, lectins (carbohydrate binding proteins) or boronic acids as the sensing element, but instability and biocompatibility has hindered development. This has presented an 0pp0l1unity for supramolecular chemists to make synthetic lectins for glucose that respond in real time to glucose in the blood. However, carbohydrate recognition in water presents a challenge due to the hydromimetic nature of the substrate. Moreover, subtle s

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8

Andersson, Pontus. "Comparison of Lectins and their suitability in Lectin Affinity Chromatography for isolation of Glycoproteins." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-417024.

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Virtually all extracellular proteins in humans are glycoproteins and likewise are many biopharmaceuticals. The glycosylation is directly correlated to biological function and stability of these proteins. The ability to isolate glycoproteins is thus of great importance in many applications. The most common isolation method for glycoproteins is affinity chromatography using lectins, a ubiquitous and versatile group of carbohydrate-binding proteins. The lectin Concanavalin A (ConA) has long been used for this purpose but suffers from undesired leakage into the eluate, causing an inquiry of altern

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9

Sousa, Bruno Lopes de. "CaracterizaÃÃo estrutural das formas silvestre e recombinante de uma lectina de sementes de Vatairea macrocarpa Benth e anÃlise das suas bases moleculares de ligaÃÃo ao antÃgeno Tn." Universidade Federal do CearÃ, 2014. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13196.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>As lectinas consitem em uma classe diversificada de proteÃnas, capazes de reconhecer estruturas glicÃdicas de forma reversÃvel e com alta especificidade, no entanto sem alterar suas estruturas quÃmicas, participando de vÃrios processos celulares importantes. Dentre as diferentes famÃlias de lectinas, as isoladas a partir de leguminosas sÃo as mais extensivamente estudadas, havendo sido relatada a influÃncias dessas molÃculas sobre diversos processos patolÃgicos, incluindo a carcinogÃnese. NotÃveis propriedades antitumorais tÃm si

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10

Howgego, Joshua David. "Synthetic lectins with novel selectivity." Thesis, University of Bristol, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.573385.

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Carbohydrates are the most plentiful organic molecules on the surface of the earth and also some of the most complex. They are not just fuel sources, but also function as identifying markers for cells, on the surfaces of which they reside in the form of glycoconjugates. These identifying molecules are recognised by lectins; proteins which bind carbohydrates through non-covalent interactions. This recognition mediates a whole range of important biological processes, from fertilisation to infection with pathogens. 'Synthetic lectins' in the context of this thesis are artificially designed and sy

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Peron, Gabriela. "Tabhys: um peptídeo com atividade lectínica extraído de Tabernaemontana hystrix." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/17/17147/tde-11112015-155331/.

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Lectinas são proteínas que possuem pelo menos um domínio não catalítico que se liga reversível e especificamente a um monossacarídeo ou oligossacarídeo. A capacidade de ligação a diferentes tipos de açúcares torna essas moléculas ferramentas úteis no estudo de diversos processos celulares específicos. Embora as lectinas de plantas sejam amplamente estudadas, aquelas referentes à família Apocynaceae ainda são pouco exploradas. Resultados prévios obtidos pelo nosso grupo de pesquisa mostraram que extratos brutos de súber do caule da apocinácea Tabernaemontana hystrix Steud apresenta atividade h

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Didak, Blanka. "Synthèse de néoglycoconjugués et dendrimères glycomimétiques utilisés pour le développement de puces à lectines de type C et leur validation." Thesis, Université Grenoble Alpes (ComUE), 2018. http://www.theses.fr/2018GREAV036.

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Les lectines de type-C (CLR) sont des protéines de liaison au glycane qui reconnaissent les sucres de manière dépendante du Ca2+. Ils ont des rôles divers dans l'organisme humain. Ils sont responsables des interactions et de l'internalisation d'agents pathogènes tels que Candida albicans, Mycobacterium tuberculosis, le VIH ou le virus Ebola. Ils sont également impliqués dans le développement ou la prévention du cancer par la reconnaissance de glycanes spécifiques exprimés à la surface des cellules tumorales.L'importance cruciale est de trouver des ligands pour les CLR qui induiront une réponse

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13

Murarasu, Thomas. "The Shiga Toxin B-Subunit : a Promising Scaffold for the Targeting of Tumor Specific Glycosphingolipids." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS512.

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Le cancer représente la second cause de décès au monde. Le développement de traitements innovants contre le cancer repose aujourd’hui sur l’identification de biomarqueurs des tumeurs et le développement de produits thérapeutiques capables de reconnaitre ces marqueurs de façon spécifique. Ces produits thérapeutiques de nouvelles générations ont le potentiel d’éliminer spécifiquement les cellules tumorales et donc de réduire les effets secondaires des traitements ainsi que les risques de rechute. Malheureusement, un certain nombre de patients ne peuvent bénéficier de ces traitements, du fait de

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Coelho, Mirela Batista. "Estudo da atividade inseticida e pro-inflamatoria da lectina isolada de sementes de 'Annona coriacea' Mart." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314522.

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Orientador: Maria Ligia Rodrigues Macedo<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-06T16:03:12Z (GMT). No. of bitstreams: 1 Coelho_MirelaBatista_D.pdf: 2076971 bytes, checksum: 2ad2d77c61af65420ba1c0a4c66e5571 (MD5) Previous issue date: 2006<br>Resumo: As lectinas são um grupo de proteínas e/ou glicoproteínas que se ligam específica e reversivelmente a carboidratos. Estudos têm demonstrado que essas proteínas possuem importantes atividades biológicas como atividade inseticida contra insetos e respostas imunológicas e

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Goto, Leandro Seiji. ""Estudos estruturais e funcionais sobre duas lectinas: cadeia B recombinante da pulchellina & Camptosemina"." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-29032007-121740/.

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Lectinas estão situadas dentro de um grupo estruturalmente diverso de proteínas que se ligam a carboidratos e glicoconjugados com grande especificidade. Encontradas em diversos organismos, elas são moléculas extremamente úteis na caracterização de sacarídeos, como agentes mediadores de endereçamento de fármacos ou até mesmo como marcadores de superfície celular. A pulchellina é uma glicoproteína heterodimérica ligante de D-Galactose oriunda de sementes de Abrus pulchellus e classificada como proteína inativadora de ribossomo do tipo 2 (type 2 ribosome-inactivating protein - type 2 RIP). A ca

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16

de, Oliveira Jose T. A. "Seed lectins : the effects of dietary Phaseolus vulgaris lectins on the general metabolism of monogastric animals." Thesis, University of Aberdeen, 1986. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU367276.

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Rats, mice, pigs, quails, chickens, steers and even some insects are unable to grow properly and in some cases die when fed on diets containing raw kidney bean (Phaseolus vulgaris). Although this problem has been extensively studied the precise mechanism of the interference of dietary antinutritional factors with the growth and health of these animals or insects is still not completely understood. In the present work, the toxic effects of the purified kidney bean globulin lectins upon the general metabolism of the rats were studied. The results of the experiments indicated that both qualitativ

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17

Odom-Crespo, Eric William. "F-type lectins biochemical, genetic, and topological characterization of a novel lectin family in lower vertebrates /." College Park, Md. : University of Maryland, 2004. http://hdl.handle.net/1903/1437.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2004.<br>Thesis research directed by: Marine-Estuarine-Environmental Sciences. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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Lu, Jinhua. "Mammalian lectins containing collagen-like domains." Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303657.

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Gupta, G. "Artificial lectins : biomimetic ligands for glycoproteins." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599789.

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This thesis describes the rational design and synthesis of selective and sterilisable biomimetic ligands for the resolution of glycosylated and carbohydrate depleted protein forms. Based on the principles of natural carbohydrate recognition, a putative library of 196 glycoprotein-binding ligands was designed and synthesised by solid phase combinatorial approaches. A preparative affinity chromatography screening assay against a well-characterised complex-type model glycoprotein, helped identify a triazine-based acyclic immobilised ligand 11/11, comprising <I>bis</I>-benzylamine substituents as

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Sampaio, Alexandre Holanda. "Lectins from Ulva and Ptilota species." Thesis, University of Portsmouth, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.310389.

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SILVA, Flávio de Oliveira. "Atividade moduladora da lectina isolada das sementes de Canavalia brasiliensis." Universidade Federal Rural de Pernambuco, 2012. http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/4585.

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Submitted by (lucia.rodrigues@ufrpe.br) on 2016-06-02T14:14:51Z No. of bitstreams: 1 Flavio de Oliveira Silva.pdf: 1881383 bytes, checksum: d592819e85426667e7752e0e6bcbbf0f (MD5)<br>Made available in DSpace on 2016-06-02T14:14:51Z (GMT). No. of bitstreams: 1 Flavio de Oliveira Silva.pdf: 1881383 bytes, checksum: d592819e85426667e7752e0e6bcbbf0f (MD5) Previous issue date: 2012-02-02<br>Lectins are proteins that bind specifically and reversibly to carbohydrates, showing several biological effects. In this work, we carried out a literature review about biological effects of lectin extract

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JÃnior, Francisco Nascimento Pereira. "PurificaÃÃo, caracterizaÃÃo parcial e cristalizaÃÃo de uma lectina ligante de manose das sementes de Platymiscium floribundum Vogel." Universidade Federal do CearÃ, 2011. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=5882.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>As sementes de Platymiscium floribundum Vogel, uma espÃcie pertencente Ã famÃlia Leguminosae, subfamÃlia Papilionoideae, tribo Dalbergieae, possuem uma lectina manose/N-acetil-D-glicosamina especÃfica, que aglutina eritrÃcitos nativos ou tratados com enzimas proteolÃticas de coelho. A lectina de sementes de P. floribundum foi purificada por precipitaÃÃo com sulfato de amÃnio seguida por cromatografia de afinidade em matriz de Sepharose-manose. Esse procedimento resultou na lectina purificada, nomeada de PFL. O processo de purificaÃ

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Landim, PatrÃcia Gadelha de Castro. "Xiloglucanas e galactomananas de leguminosas: interaÃÃo com lectinas D-galactose-ligantes." Universidade Federal do CearÃ, 2007. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=8583.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>PolissacarÃdeos ocorrem em grandes quantidades nas sementes como componentes da parede celular ou como reserva. Dentre estes Ãltimos, incluem-se as xiloglucanas cotiledonÃrias e as galactomananas endospÃrmicas. As xiloglucanas apresentam uma cadeia principal de β-D-(1→4)-glucana ramificada com ligaÃÃes α-(1→6) por resÃduos D-xilopiranosÃdeos ou β-D-galactopiranosÃdeo-(1→2)-D-xilopiranosÃdeos, enquanto as galactomananas endospÃrmicas consistem em cadeias polimÃricas de resÃduos β-D-manopiranos

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Lobo, Marina Duarte Pinto. "AnÃlise proteÃmica de plasma de pacientes com cÃncer de mama utilizando lectinas vegetais e label-free LC-MSE." Universidade Federal do CearÃ, 2016. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=16410.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>O cÃncer de mama representa o tipo de cÃncer mais comum entre as mulheres no mundo e no Brasil, depois do cÃncer de pele nÃo melanoma. Caracterizando-se como uma doenÃa clÃnica e biologicamente heterogÃnea, a detecÃÃo precoce do cÃncer de mama, uma caracterizaÃÃo fidedigna da doenÃa e um diagnÃstico preciso sÃo de fundamental importÃncia para reduÃÃo da mortalidade. Assim, o objetivo do presente trabalho foi realizar anÃlises qualitativas e quantitativas de proteÃnas plasmÃticas de mulheres saudÃveis e mulheres com cÃncer de mama

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Sousa, Bruno Lopes de. "Caracterização estrutural das formas silvestre e recombinante de uma lectina de sementes de Vatairea macrocarpa Benth e análise das suas bases moleculares de ligação ao antígeno Tn." reponame:Repositório Institucional da UFC, 2014. http://www.repositorio.ufc.br/handle/riufc/18875.

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SOUSA, Bruno Lopes de.Caracterização estrutural das formas silvestre e recombinante de uma lectina de sementes de Vatairea macrocarpa Benth e análise das suas bases moleculares de ligação ao antígeno Tn. 2014. 119 f. Tese (Doutorado em Bioquímica)-Universidade Federal do Ceará, Fortaleza-CE, 2014.<br>Submitted by Eric Santiago (erichhcl@gmail.com) on 2016-07-20T12:14:08Z No. of bitstreams: 1 2014_tese_blsousa.pdf: 4344064 bytes, checksum: 784bc6294f0c6ff7014ef6c5ecece099 (MD5)<br>Approved for entry into archive by José Jairo Viana de Sousa (jairo@ufc.br) on 2016-08-02T20:33:39Z (GMT) No. of

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Landim, Patrícia Gadelha de Castro. "Xiloglucanas e galactomananas de leguminosas: interação com lectinas D-galactose-ligantes." reponame:Repositório Institucional da UFC, 2007. http://www.repositorio.ufc.br/handle/riufc/18846.

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LANDIM, Patrícia Gadelha de Castro. Xiloglucanas e galactomananas de leguminosas: interação com lectinas D-galactose-ligantes. 2007. 100 f. Dissertação (Mestrado em Bioquímica) - Universidade Federal do Ceará, Fortaleza-CE, 2007.<br>Submitted by Eric Santiago (erichhcl@gmail.com) on 2016-06-27T12:54:01Z No. of bitstreams: 1 2007_dis_pgclandim.pdf: 1768165 bytes, checksum: f8cb9e6a16de4f08d984b33f047c8bd5 (MD5)<br>Approved for entry into archive by José Jairo Viana de Sousa (jairo@ufc.br) on 2016-08-02T20:08:26Z (GMT) No. of bitstreams: 1 2007_dis_pgclandim.pdf: 1768165 bytes, checksum: f8cb9e6

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Kohatsu, Luciana. "Novel roles for human lectins in innate defense against pathogens." Diss., Restricted to subscribing institutions, 2006. http://proquest.umi.com/pqdweb?did=1155572661&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Johansson, Emma M. V. "Combinatorial discovery of glycopeptide dendrimers targeting lectins /." [S.l.] : [s.n.], 2009. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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Vieira, Breitwieser Otilia. "Leguminous lectins bind non specifically to DNA." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=972705589.

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Hutchinson, Oliver Clyde. "The isolation and characterization of fungal lectins." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322949.

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Al-Abbasi, Fahad Ahmed. "Application of lectins to specific analytical problems." Thesis, University of Newcastle Upon Tyne, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.438401.

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Carter, Tom Scott. "Synthetic lectins with pyrene at the core." Thesis, University of Bristol, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.702443.

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Carbohydrates are displayed on the outer layer of cells by glycoproteins and glycolipids, forming the glycocalyx. These carbohydrates hold a huge amount of information, acting as a cell 'barcode', facilitating communication and acting as targets for pathogens. The proteins which recognise carbohydrates in nature are called lectins. Synthetic mimics of these proteins, binding through noncovalent interactions in water, are termed 'synthetic lectins'. The design and synthesis of these synthetic lectins could allow reading of parts of the cell barcode and give a greater understanding of the operat

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Barroso, Neto Ito Liberato. "Resolução da estrutura tridimensional de uma lectina de sementes de Canavalia grandiflora Benth. com efeitos sobre mecanismos inflamatórios." reponame:Repositório Institucional da UFC, 2010. http://www.repositorio.ufc.br/handle/riufc/18171.

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BARROSO NETO, Ito Liberato. Resolução da estrutura tridimensional de uma lectina de sementes de Canavalia grandiflora Benth. com efeitos sobre mecanismos inflamatórios. 2010. 103 f. Dissertação (Mestrado em Bioquímica) - Universidade Federal do Ceará, Fortaleza-CE, 2010.<br>Submitted by Eric Santiago (erichhcl@gmail.com) on 2016-05-25T12:16:49Z No. of bitstreams: 1 2010_dis_ilbarrosoneto.pdf: 2893401 bytes, checksum: 790650a62ad9b6de91f47b92f3115778 (MD5)<br>Approved for entry into archive by José Jairo Viana de Sousa (jairo@ufc.br) on 2016-07-05T19:29:27Z (GMT) No. of bitstreams: 1 2010_di

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Oliveira, Mara Rubea Tinoco Rodrigues de. "Avaliação in vitro do efeito de lectinas de sementes de Talisia esculenta e Labramia bojeri sobre o biofilme oral." [s.n.], 2005. http://repositorio.unicamp.br/jspui/handle/REPOSIP/288965.

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Orientadores: Francisco Carlos Groppo, Maria das Graças Machado Freire<br>Dissertação (mestrado profissional) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-06T09:31:23Z (GMT). No. of bitstreams: 1 Oliveira_MaraRubeaTinocoRodriguesde_M.pdf: 229602 bytes, checksum: 5369ca1218480e5687d9ee3827b671ce (MD5) Previous issue date: 2005<br>Resumo: A medicina natural e complementar, especialmente a fitoterapia, suprem as necessidades em saúde de grande parte da população, particularmente nos países em desenvolvimento. Dentre os fitote

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Silveira, Willian Abraham da. "Avaliação da interação entre galectina-1 e zinco e suas potenciais implicações estruturais e funcionais." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/60/60135/tde-05072011-122646/.

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Introdução: A Galectina-1 (Gal-1) é uma proteína multifuncional capaz de reconhecer, de modo específico, glicanas compostas por resíduos de -galactosídeos, por meio de domínios de reconhecimento de carboidrato (CRD). A Gal-1 é um homodímero de 14.900 daltons, pI = 5.6, apresenta uma topologia molecular do tipo jelly-roll composto por duas folhas- anti-paralelas. Além disso, esta proteína não apresenta peptídeo sinal e possui 6 cisteínas, 7 ácidos glutâmicos, 9 ácidos aspárticos e 4 histinas por monômero. A Gal-1 liga-se a diferentes moléculas biológicas contidas nas superfícies celulares, núcl

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Carding, S. R. "Immunochemical studies of mammalian beta-galactoside ?-binding lectins." Thesis, University of Cambridge, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.352601.

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Barwell, Nicholas P. "Synthetic lectins : biomimetic receptors for carbohydrates in water." Thesis, University of Bristol, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495920.

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Raemaekers, Romaan J. M. "Expression of functional plant lectins in heterologous systems." Thesis, Durham University, 2000. http://etheses.dur.ac.uk/4621/.

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The mannose-binding lectin from snowdrop (Galanthus nivalis agglutinin; GNA) was produced in Escherichia coli and purified as a functional protein after denturation/renaturation. Incorporation of the four extra C-terminal residues recently revealed from X-ray crystallographic data demonstrated that these residues increase binding to the glycoprotein carboxypeptidase Y. However, no differences in activities were observed in haemagglutination assays when compared to native GNA and toxicity towards rice brown planthopper (Nilaparvata lugens', BPH) in artificial diet bioassays was unaltered. Site-

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Woodhouse, Stephen David. "Binding and toxicity of plant lectins to insects." Thesis, Durham University, 2002. http://etheses.dur.ac.uk/4103/.

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The toxicity of plant lectins to insects after oral ingestion was investigated by incorporating the proteins into insect diets. Bioassays carried out using an artificial diet system demonstrated that kidney bean (Phaseolus vulgaris) lectin (PHA) caused a significant decrease in survival of larvae of the tomato moth, Lacanobia oleracea. Jackfruit (Artocarpus integrifolia) lectin (jacalin) and black mulberry (Morus nigra) lectin both caused a significant decrease in growth of the peach potato aphid (Myzus persicae) when compared to controls in an artificial diet based bioassay. Interactions of l

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Fontinopoulou, Angeliki. "Investigating the glycosylation of recombinant glycoproteins with lectins." Thesis, University of Newcastle Upon Tyne, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432779.

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Nantwi, Paul Kwasi Kankam. "Lectins in drug delivery to the oral cavity." Thesis, University of Portsmouth, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.482091.

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Lectins are proteins or glycoproteins of non-immune origin, capable of specific interaction with, and reversible binding to carbohydrate moieties of complex glycoconjugates. Lectins are ubiquitous in nature and are present in all living organisms. In nature lectins are implicated in cell recognition and adhesion processes, and have been described as "second generation" mucoadhesives. The aim of this project was to identify lectins that could be incorporated into dosage forms to allow their retention within the oral cavity. This would allow prolonged localised drug delivery. Initial screening s

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Renney, Charles M. "Novel synthetic lectins for carbohydrate recognition in water." Thesis, University of Bristol, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686165.

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Carbohydrate recognition in water still remains one of the most challenging tasks for supramolecular chemists. Despite the challenges, the Davis group has had good success in designing and synthesising compounds capable of carbohydrate recognition. Within this body of work 6 novel carbohydrate receptors are reported, based upon the anthracene design shown below. The majority of the reported receptors displayed good to excellent affinities to all-equatorial carbohydrates. One of the synthesised receptors, containing methoxy functionality on the anthracene units, demonstrated remarkably high aff

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Kaspar, Amir Shermila. "Synthetic lectins with ethylene spacers recognition in water." Thesis, University of Bristol, 2017. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738277.

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Zelensky, Alex N. "In silico analysis of C-type lectin domains' structure and properties /." View thesis entry in Australian Digital Theses Program, 2004. http://thesis.anu.edu.au/public/adt-ANU20050318.185314/index.html.

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Thesis (Ph.D.)--Australian National University, 2004.<br>"This CD contains the software (mostly written in Perl) used for comparative structure analysis reported in Chapter 4 (str_comp directory), and for the CTLD database system described in Chapter 2 (CTLD_DB directory)."

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Defaus, Fornaguera Sira. "Glycoprobes for capture and identification of lectins from biological sources." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/277290.

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Glycosylation is a posttranslational modification affecting the fast majority of cellular surfaces through glycolipids and glycoproteins. It has been estimated that over 80% of all proteins are glycosylated and that the glycans decorating the periphery of these molecules are fundamental for the biological function of the entity. Many of these functions have yet to be unraveled. As the modification is a secondary-gene event, it depends on the availability and activity of a set of glycosyltransferases, the availability of both donor and acceptor substrate (both in time and place), as well as man

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Tajra, FÃbio Solon. "Biotechnological potential of the red marine alga Hypnea musciformis (HML) applied to Dentistry." Universidade Federal do CearÃ, 2010. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=5285.

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FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico<br>Dental Caries is an infectious disease naturally multi-factorial that begins in the childhood, able to spread its intensity and prevalence according to the mouth ambient conditions of each host. The risk of the patients to develop, in some time of their lives, carious lesions can be measured through a complex analysis using health determinant factors and other specific factors of the health-disease process. Since the dental caries forward diagnostic as well as the review of the auxiliary determinant factors of the dental

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Correia, Jorge Luis Almeida. "PurificaÃÃo, caracterizaÃÃo parcial e potencialidade biotecnolÃgica de trÃs lectinas de sementes de espÃcies de Leguminosae da subtribo Diocleinae." Universidade Federal do CearÃ, 2015. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=17238.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico<br>Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>Leguminosae is recognized by the large amount of isolated and characterized lectins, especially seeds. In this group stand out proteins extracted from species belonging to subtribe Diocleinae, the number of studies in different areas of knowledge. Lectins can be defined as proteins or glycoproteins which are not originated from a body's immune response and have the ability to recognize and bind

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Sun, Yedi. "Novel Functionalized Lectins Engineered by Affinity-Guided DMAP Chemistry." 京都大学 (Kyoto University), 2013. http://hdl.handle.net/2433/174964.

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Gemma, Emiliano. "Synthesis of Oligosaccharides for Interaction Studies with Various Lectins." Doctoral thesis, Stockholm : Department of Organic Chemistry, Stockholm University, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-459.

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Banchonglikitkul, Chuleratana. "Lectins in drug delivery to the eye and mouth." Thesis, University of Portsmouth, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323275.

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