Academic literature on the topic 'Left median fissure'
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Journal articles on the topic "Left median fissure"
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Sudarshana, Smita. "Variations of Fissures and Lobes in Human Lungs: A Cadaveric Study." International Journal of Pharmaceutical and Clinical Research 16, no. 9 (2024): 290–98. https://doi.org/10.5281/zenodo.13896092.
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<strong>Introduction:</strong> Accurate knowledge of variations in the fissures and lobes of the lungs is of paramount importance for cardiothoracic surgeons to perform lobectomies, segmental resection of the infected bronchopulmonary segments, and to lessen post- operative complications like air leaks. Likewise, it is equally important for radiologists to correctly interpretate Chest-X-ray, CT scans MRIs of the chest. <strong>Aim: </strong>To observe and describe the variation in fissures and lobes in human lungs. <strong>Material and Methods: </strong>The study was conducted on 54 lungs (28 right and 26 left), well preserved in formalin, from various medical colleges of Patna, Bihar. A gross examination was done to find out the presence of incomplete oblique fissures of the right and left lungs; incomplete horizontal fissures of the right lung; along with their grades. The absence of a horizontal fissure in the right lung and the presence of accessory fissures were also observed. Photographs of the observed variations were taken. The Percentages of the variations were calculated and compared with the previous studies. <strong>Result</strong><strong>:</strong> Among the right-sided lungs, complete oblique fissures and complete horizontal fissures were found in 28.5% (8/28) and 35.7% (10/28) respectively. Four out of twenty-six (15.3%) left-sided lungs had complete oblique fissures. Incomplete oblique fissures and incomplete horizontal fissures in right-sided lungs were found in 71.4% (20/28) and 42.8% (12/28) respectively. 84.6% (22/26) of the left-sided lungs had incomplete oblique fissures. Absence of oblique fissure was not found in any of the lungs examined (0/54), while 21.5 % (6/28) of the right-sided lungs had absent horizontal fissure. Left median fissure, a type of accessory fissure, were found in 6 out of 26 lungs examined (23.1%). <strong>Conclusion: </strong>The present study has found high percentages of incomplete oblique fissures; low percentages of complete oblique fissures and complete horizontal fissures; compared to many studies done so far. This highlights the possibilities of a wider range of variations and necessitates more research to find out the extend of variations.
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Peng, Yuanyuan, Hualan Zhong, Zheng Xu, Hongbin Tu, Xiong Li, and Lan Peng. "Pulmonary Lobe Segmentation in CT Images Based on Lung Anatomy Knowledge." Mathematical Problems in Engineering 2021 (April 19, 2021): 1–15. http://dx.doi.org/10.1155/2021/5588629.
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In computed tomography (CT) images, pulmonary lobe segmentation is an arduous task due to its complex structures. To remedy the problem, we introduce a new framework based on lung anatomy knowledge for lung lobe segmentation. Firstly, the priori knowledge of lung anatomy is used to identify the fissure region of interest. Then, an oriented derivative of stick filter is applied to isolate plate-like structures from clutters for lobar fissure verification. Finally, a surface fitting model is employed to complete the incomplete fissure surface for lung lobe segmentation. Compared with manually segmented fissure references, the designed approach obtained a high median F1-score of 0.8865 in the left lung and obtained a high median F1-score of 0.9200 in the right lung. The average percentages of the segmented lung lobes in the lung lobe ground truth are 0.960, 0.989, 0.973, 0.920, and 0.985 for the left upper, left lower, right upper, right middle, and right lower lobes, respectively. The perfect performance of the proposed scheme is tested by visual inspection and quantitative evaluation.
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Falcão, Mário Sérgio A., Rafael V. Monteiro, Clarissa M. Carvalho, Hudson H. de Andrade, and Paula D. Galera. "Reference values for selected ophthalmic tests of the blue-and-yellow macaw (Ara ararauna)." Pesquisa Veterinária Brasileira 37, no. 4 (2017): 389–94. http://dx.doi.org/10.1590/s0100-736x2017000400014.
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ABSTRACT: The aim of this study was to establish reference values for selected ophthalmic diagnostic tests in healthy blue-and-yellow macaws. We investigated a total of 35 adult macaws (70 eyes) of undetermined sex and with an average weight of 1 kg, who were living in captivity in the Federal District, Brazil. Tear production using the Schirmer tear test (STT), normal conjunctival flora, intraocular pressure (IOP) using a rebound tonometer and horizontal palpebral fissure length (HPFL) were evaluated. In this study, 84.1% of samples were positive for microbial growth. Bacteria, fungi and yeasts were isolated, and Staphylococcus spp. (21.9%) and Bacillus spp. (26.8%) were the most frequently isolated microorganisms. The mean value for STT was 7.6±4.6mm/min in the right eye (OD) and 6.6±4.4mm/min in the left eye (OS) (median = 7,11±0,76mm/min). Mean IOP was 11.4±2.5mm Hg OD and 11.6±1.8mm Hg OS (median = 11.49±0.22mm Hg), prior to anesthesia, and 7.6±2.4mm Hg OD and 7.8±1.8mm Hg OS (median 7.71±0.08mmHg) after anesthesia. The IOP was significantly lower when the animals were under anesthesia as compared to when they were conscious (p≤0.05). Horizontal palpebral fissure length was 11.7±0.1mm OD and 11.8±0.1mm OS (median = 11.72±0.07mm). The STT showed a positive correlation with palpebral fissure measurement for this species. These selected ophthalmic reference values will be particularly useful in diagnosing pathological changes in the eyes of blue-and-yellow macaws.
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Kosuge, Atsushi, Yukihiro Yoshida, Masaya Yotsukura, and Shun-ichi Watanabe. "En bloc upper and lower lobe bisegmentectomy for non-small-cell lung cancer invading the fissure." Japanese Journal of Clinical Oncology 55, no. 2 (2024): 194–97. https://doi.org/10.1093/jjco/hyae140.
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Abstract Background The optimal surgical procedure for tumors extending deep into the lung parenchyma of the opposite lobe beyond the fissure remains controversial. The current study aimed to examine whether en bloc upper and lower lobe bisegmentectomy can be an option for such tumors. Methods This study included patients who underwent surgery for cN0 non-small-cell lung cancer invading the adjacent lobe beyond the fissure between the upper and lower lobes. The perioperative and long-term outcomes of the bisegmentectomy and extended lobectomy/pneumonectomy groups were compared. Results The bisegmentectomy group included five patients who underwent right S2 + S6 segmentectomy and four patients who underwent left S1 + 2 + S6 segmentectomy. The bisegmentectomy and extended lobectomy/pneumonectomy groups had similar perioperative outcomes. The median surgical duration, volume of blood loss and length of hospital stay of the bisegmentectomy group were 175 min, 79 mL and 5 days, respectively. In the bisegmentectomy group, one patient with a tumor without a ground-glass component on computed tomography scan had brain metastasis and died. The remaining eight patients with tumors with ground-glass components on computed tomography scan were alive without recurrence at a median follow-up of 7.2 years. In the extended lobectomy/pneumonectomy group, all patients experienced recurrence and died at a median follow-up of 3.9 years. Conclusions En bloc upper and lower lobe bisegmentectomy can be a safe and feasible option for tumors with a ground-glass component on computed tomography scan in patients with non-small-cell lung cancer invading the adjacent lobe beyond the fissure.
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Vovk, V. V., and V. P. Nespriadko. "EVALUATION OF CEPHALOMETRIC ANALYSIS IN PATIENTS WITH BILATERAL CONDYLAR RETROPOSITION IN TEMPOROMANDIBULAR DYSFUNCTION." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 20, no. 3 (2020): 41–46. http://dx.doi.org/10.31718/2077-1096.20.3.41.
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Relevance. During the dentoalveolar growth and development, the direction and growth type of facial skull play a very important role. Development of esthetical symmetry, functional relationship, and clinical disharmony depends on skull parameters. Temporomandibular joint dysfunction is one of the most common diseases nowadays. That is why early identification of risk factors is among the priorities. This study aimed at evaluating occlusional and skeletal specific characteristics in patients with temporomandibular joint dysfunction, comparing different cephalometric findings and CT findings relating to condylar position. Materials and methods. The study included 45 individuals. The study group consisted of 26 patients with bilateral condylar retroposition. Control group was made up of 19 patients. The participants underwent clinical examination, functional testing, palpation of masticatory muscles, occlusion diagnosis by applying Baush articulating film 200,100,8 microns, cephalometric analysis: Tweed, Kim, Jarabak, Ricketts, computed tomography of temporomandibular joint. Statistical analysis was carried out by the program IBM SPSS Statistic Base v.22. Results. There were no pathological contacts during evaluation of static and dynamic occlusion, laterotrusion as «canine guidance». The patients of the test group had bilateral posterior joint fissure reduced right-median 1,96, left-median 1,81. In control group the position was right-average 2,75 and left-median 2,67 The patients in the control and test groups the indices Tweed <FMA average were 19,6°/ median 21,7°; <IMPA average 97,9°/ median 97,8°; Kim ODI median was 68,9°/73,74°; Ricketts Overbite median 2.1 mm /1,9 mm, Overjet median was 2,9 mm /2,85 mm, PM-Xi-ANS median was 44,1°/43,75°, <NPog-FH median was 91°/86,85°,<NBa-PtGn median was 91,1°/90,1°, <MeGo-FH median was 18,7°/22,4°; Jarabak <N-S-Ar average was 127,2°/125,6 °. Conclusions. In the patients with bilateral condylar retropositionm the joint fissure is reduced. Cephalometric analysis demonstrated the following: Tweed <FMA, <IMPA; Kim ODI; Ricketts Overbite, Overjet, PM-Xi-ANS, <MeGo-FH; Jarabak <N-S-Ar can not be used as diagnostic criteria of bilateral condylar retroposition. Ricketts <NPog-FH in the test group showed the mandibular retroposition, but with normal type of mandibular growth <NBa-PtGn. It can be used as one of the primary cephalometric diagnostic indicator of bilateral condylar retroposition.
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Zuniega, Ralph Rommualdo Abareta, Julian Alejandro Santos, Romelito Jose Galvan Galsim, and Jonathan Saputil Elevazo. "Neonatal giant dural sinus ectasia: a multimodality imaging approach." BMJ Case Reports 14, no. 9 (2021): e242439. http://dx.doi.org/10.1136/bcr-2021-242439.
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Dural venous sinus ectasia is a rare anomaly characterised by the formation of a large vascular lake within the leaves of the dural sinuses, usually associated with thrombosis. These lesions can cause brain compression, cardiac insufficiency and disseminated intravascular coagulation, which may lead to poor prognosis. We present the case of a neonate who presented with an intracranial mass on prenatal ultrasound. Postnatal transcranial ultrasonography, cranial CT and cranial MRI demonstrated a large lesion predominantly occupying the dural sinus confluence, extending into the sagittal sinus, straight sinus and right transverse sinus. The left marginal sinus remains unfused and patent. Concomitant arteriovenous malformations were evident in the median interhemispheric fissure and the left Sylvian fissure. There are several published case reports and case series describing malformations of the dural sinuses in perinatal and neonatal patients in recent years, but this case is unique in that: (1) there is the presence of a vascular malformation concomitant to the dural sinus ectasia and (2) it highlights the importance of imaging in clinching the diagnosis of giant dural venous sinus ectasia, as it is often misdiagnosed as more common conditions such as extra-axial intracranial haemorrhage.
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STAN, Florin Gheorghe. "Comparative Study of the Liver Anatomy in the Rat, Rabbit, Guinea Pig and Chinchilla." Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine 75, no. 1 (2018): 33. http://dx.doi.org/10.15835/buasvmcn-vm:002717.
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In liver surgical and histological research, small rodents are the most used experimental models. Although the small animals liver is typically lobulated and its macroscopic appearance do not resemble that of the compact human liver, a high degree of lobulation equivalence, allow the use of small rodents in biomedical research. The macroscopic anatomy of the liver of the rat, rabbit, guinea pig and chinchilla was studied from a comparative standpoint. The topography, lobulation and the connection elements of the liver were examined by detailed in situ observation and explanted liver of forty specimens.The rat liver (Hepar) consists of four distinct lobes of different size: the left lateral lobe - LLL (Lobus hepatis sinister lateralis), the median lobe - ML, the right lobe – RL (Lobus hepatis dexter) and the caudate lobe CL (Lobus caudatus). The largest lobe was the median lobe. The rabbit liver consists of five lobes: left lateral lobe - LLL, left medial lobe - LML (Lobus hepatis sinister medialis), right lobe - RL, quadrate lobe – QL (Lobus quadratus) and caudate lobe - CL. The most developed lobe was the left lateral lobe. The caudate lobe had a very narrow attachment on the hilar region. The guinea pig liver show six lobes: left lateral lobe - LLL, left medial lobe - LML, right lateral lobe – RLL (Lobus hepatis dexter lateralis), right medial lobe – RML (Lobus hepatis dexter medialis), quadrate lobe - QL and caudate lobe - CL. The largest lobe of this specie was the left lateral lobe. In chinchilla liver showed four lobes like in the rat. In the rats the most developed hepatic ligament was the falciform ligament (Lig. Falciforme hepatis) which spans from xyphoid process of the sternum and diaphragm to the liver, beginning at the interlobular fissure. The coronary ligament (Lig. Coronarium hepatis) was well developed in all rats. Interlobular ligaments connect the left lateral lobe with the upper caudate lobe. In rabbits, guinea pigs and chinchillas the connection elements were represented by the falciform ligament, coronary ligament, right (Lig.triangulare dextrum) and left triangular ligaments (Lig. Triangulare sinistrum), hepatorenal ligament (Lig.hepatorenale) and hepatoduodenal ligament (Lig. hepatoduodenale) with varying degrees of development.Based on detailed study of the macroscopic anatomy of rat, rabbit, guinea pig and chinchilla a proper experimental model in liver research, could be assessed. In this regard, the vascular anatomy of the liver in the mentioned species is of a great importance and it is subject of another report.
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Amrina, Fadillah, Riani Erna, and E. Iskandar. "Clinical Characteristics of Post-surgical Ptosis Patients at Dr. Mohammad Hoesin General Hospital Palembang." Sriwijaya Journal of Ophthalmology 5, no. 2 (2022): 160–67. http://dx.doi.org/10.37275/sjo.v5i2.76.
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Introduction: Blepharoptosis is drooping of the upper eyelid in a primary position, causing the narrowing of the palpebral fissure. This condition can partially or completely cover the visual axis. Establishing the diagnosis of ptosis requires a comprehensive eye examination, including history taking, physical examination, and examination of the eyelids in ptosis patients. The majority of patients with ptosis require surgery, and clinical characteristics play an important role in classifying the type of ptosis and then formulating a detailed treatment plan strategy so that a better outcome is obtained.
 Methods: A descriptive retrospective study was conducted from medical records of post-surgical ptosis patients at Dr. Mohammad Hoesin Hospital Palembang from January 2016 to December 2021. The data taken included age, gender, the onset of occurrence, laterality, type of ptosis based on the onset, vertical palpebral fissure (FPV), horizontal palpebral fissure (FPH), margin-reflex distance (MRD), margin limbal distance (MLD), lid lag, bell's phenomenon levator muscle function, type of ptosis surgery and postoperative condition. This study aims to determine the clinical characteristics of patients with ptosis at Dr. Mohammad Hoesin Hospital Palembang.
 Results: Of the 57 ptosis patients in this study, the majority of patients were male, as many as 32 patients (56.1%) with the age category >40 years, as many as 24 patients (42.1%) with unilateral lateral ptosis as many as 50 patients (87.7%) with the more frequent comparison was the left eye in 29 patients (58%). Acquired ptosis was the most common cause in this study in as many as 46 patients (80.7%), and the most common mechanism of acquired ptosis was neurogenic (33.3%). The majority of patients had no previous surgical history of 41 patients (71.9%), moderate levator function of as many as 42 (73.7%), and frontal suspension surgery technique with synthetic materials as many as 17 (34%) patients. the mean FPV was 5.08±2.627 with a median of 5.00 (0-11), FPH 25.94±1.726 with a median of 26.00 (20-29), MRD 0.246±1.78 with a median of 0.00 (-4 -5), MLD 4.789±2.801 with a median of 5.00 (-4-11) and LA 7.16±4.083 with a median of 7.00 (0-14). Ptosis patients had negative lid lag in 47 patients (82.5%) and positive bell's phenomenon in 49 patients (86%). The postoperative condition of ptosis patients was satisfactory where there was no recurrence and reoperation of ptosis, postoperative complications as many as 1 (1.8%) patients experienced overcorrection, 6 (10.5%) patients experienced lagophthalmos, and 2 (3.5%) patients had an outcome. asymmetric.
 Conclusion: Clinical characteristics of ptosis patients can determine the diagnosis and treatment that will be given to the patient.
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Scarone, Pietro, Delphine Leclerq, Françoise Héran, and Gilles Robert. "Long-term results with exophthalmos in a surgical series of 30 sphenoorbital meningiomas." Journal of Neurosurgery 111, no. 5 (2009): 1069–77. http://dx.doi.org/10.3171/2009.1.jns081263.
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Object The authors analyzed the long-term results and radiological aspects of sphenoorbital meningioma (with emphasis on exophthalmos) in a series of 30 patients who underwent resection. Methods Data obtained in all 30 patients who underwent surgery for typical sphenoorbital meningioma at the authors' institution between June 1994 and September 2005 were analyzed retrospectively. The exophthalmos index (EI) was measured on preoperative MR images and/or CT scans and compared between the early and last follow-up examinations. All patients were women 35–74 years of age (median 51 years). Exophthalmos was the presenting symptom in 28 patients (93%), and was observed on preoperative MR images in all patients. The median duration of symptoms before surgery was 10 months (2–120 months). Results Total resection (Simpson Grade I) was not achieved in these patients because of the impossibility of resecting the dura mater in the superior orbital fissure without causing significant complications. Subtotal resection (Simpson Grade II) was obtained in 90% of patients, and in 3 patients (10%) a portion of the tumor was deliberately left in place because of extensive macroscopic infiltration of the cavernous sinus and/or extraocular muscles (Simpson Grade III). No patient died. Radiological evaluation at a median follow-up of 61 months (range 17–136 months) showed no contrast enhancement in 14 patients (47%), residual contrast enhancement without evolution in 13 (43%), and recurrence (new contrast enhancement) in 3 (10%). The EI was improved at the first radiological follow-up (median 12 months) in 27 patients (90%), and at the last radiological follow-up (median 61 months) in 28 patients (93%). In the interval between the first and final imaging follow-up, the EI improved in only 8 patients (20%), worsened in 15 patients (50%), and showed no variation in 7 patients (30%). Conclusions Sphenoorbital meningiomas are insidious tumors with slow progression. Even when exophthalmos is not clinically evident, it is always present on preoperative MR imaging. Total resection is not possible due to superior orbital fissure invasion, but subtotal resection (Simpson Grade II) can assure long-term stability due to the nonevolutive nature of most residual tumors. Exophthalmos improves at early radiological follow-up, but may worsen again as time passes.
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Karaketir, Sıdıka, Demet Şencan, Serdar Çolakoğlu, and Deniz Şenol. "Analysis of anthropometric measurements taken from the periocular region in healthy young individuals with different somatotypes." Indian Journal of Ophthalmology 72, no. 10 (2024): 1458–65. http://dx.doi.org/10.4103/ijo.ijo_2836_23.
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Purpose: Anthropometric parameters related with the periocular region (PR) have gained great importance with the optical technology used in the treatment of eye defects. They have also become important parameters that determine the limits of treatment in aesthetic surgery procedures in PR and the treatment of orbital diseases. The aim of this study was to examine the relationship of PR measurements with somatotype. Methods: Somatotypes were determined by using the Heath-Carter method. Ten indirect anthropometric measurements, namely nasal root (mf-mf), outer chantal distance (ex-ex), inner chantal distance (en-en), interpupillary distance (p-p), right and left palpebral fissure width (ex-en), palpebral fissure height (ps-pi), and orbital height (os-oi), were taken from PR with Image J program. Kruskal-Wallis H test was used to compare data with each other. Post-hoc Mann-Whitney U test was used to find out which group caused statistically significant differences according to the results of the Kruskal-Wallis H test. Results: A statistically significant difference was found between some indirect anthropometric measurements taken from PR and somatotypes (P < 0,05). This difference was found to result from central group somatotype, in which no somatotype component has different effects from another one, for both genders. In almost all of the indirect anthropometric measurements, it was found that balanced ectomorph somatotypes reached the highest median values, while central group somatotypes had the lowest median values. Conclusion: As a result of this study, somatotype affects the appearance of PR. It will be possible to obtain more accurate and reliable results in aesthetic surgery interventions and identification studies. Our study is the first and a pioneer in its field in the literature. It will inspire and guide future researchers, surgeons, anthropologists, and forensic doctors who will work in this field.
Book chapters on the topic "Left median fissure"
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Yang, Liu, Zedong Du, Zhiren Feng, and Bo Jin. "Spatial Characteristics of Basic Storage Media of Reservoir-Induced Earthquakes in the Lower Reaches of Jinsha River—A Case Study in Baitan-Zhilixincun." In Lecture Notes in Civil Engineering. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-7251-3_4.
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AbstractReservoir-induced earthquakes have the characteristics of shallow focal depth, small magnitude, high frequency and density in the Baitan-Zhilixincun section of the lower reaches of the Jinsha River. The rock mass of the shallow strata is mostly carbonate rock, which is widely distributed. The shallow metamorphic rocks are mainly distributed at the depth of 10 km. In the concentrated area of reservoir-induced earthquakes, the number of secondary faults is relatively large, and they are mainly reverse faults. The stress and strain patterns of the shallow cracks are mainly unloading cracks in the rock mass on the left and right banks of the Baitan-Jiaopingdu section. The main storage characteristics of groundwater are bedrock fissure water and karst fissure water. The rapid impoundment of the reservoir makes the bedrock fissure.
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Walker, Christopher M. "Upper and Middle Lobe Atelectasis." In Chest Imaging. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780199858064.003.0017.
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Upper and middle lobe atelectasis discusses the radiographic and computed tomography (CT) manifestations of upper and middle lobe atelectasis. The most common radiographic signs of right upper lobe atelectasis include upward and medial displacement of the minor fissure, superior displacement of adjacent structures such as the hilum and main bronchus, and ipsilateral shift of the mediastinal structures. The S sign of Golden results from a centrally obstructing lung cancer as the cause of the atelectasis and manifests as a reverse S configuration of the minor fissure outlined by atelectatic lung and central mass. Left upper lobe atelectasis manifests with a veil-like opacity on frontal radiography with leftward shift of upper mediastinal structures such as the trachea and upward shift of the left main bronchus and left hemidiaphragm. The Luftsichel sign or air crescent sign may be seen and represents the hyperexpanded superior segment of the left lower lobe outlining the transverse aortic arch. Lobar atelectasis in the inpatient setting is most commonly secondary to an obstructing mucus plug. Lobar atelectasis in the outpatient setting is often a heralding sign of a centrally obstructing lung cancer and should be further evaluated with contrast-enhanced CT and/or bronchoscopy.
Conference papers on the topic "Left median fissure"
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Melhado, Eliana Meire, Letícia Buzzo do Amaral, Leonardo Estrela Thomé, et al. "Neurocriptococcosis in an immunocompetent patient: a case report." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.377.
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Introduction: Cryptococcosis is an infection acquired through the lungs, the form of central nervous system involvement is neurocriptococcosis. The diagnosis is the investigation of yeasts in the cerebrospinal fluid using china ink. Treatment is amphotericin B and fluconazole. The aim is to report a case of neurocriptococcosis in an immunocompetent patient. This is a descriptive study, through the analysis of the medical record. Case report: Female, 23 years old, healthy, with severe headache for 15 days, with progressive worsening, neurological examination without changes, performed skull computed tomography (CT) scan, no changes, cerebrospinal fluid (CSF) examination showed nucleated cells 204, presence of yeast, Venereal Disease Research Laboratory (VDRL): non-reactive and culture of Cryptococcus gattii, positive China ink. Magnetic resonance imaging of the brain showed hypersignal on T2/FLAIR (T2-weighted-Fluid-Attenuated Inversion Recovery) affecting cortical sulci, encephalic fissures, cerebellar foliae and pial surface of the brainstem and diffuse leptomeningeal impregnation, volumetric reduction of the supratentorial ventricular system, suggestive of cerebrospinal fluid hypotension, findings of leptomeningitis, related to cryptococcosis. Treatment with amphotericin B and fluconazole was initiated. Patient with onset of focal neurological deficits, amaurosis and dysarthria. She presented with refractory headache, requiring serial liquoric punctures for relief of intracranial hypertension. She evolved with instability and underwent a right ventriculoperitoneal shunt. Postoperatively, he presented left hemiparesis. Skull CT showed hematoma and emphysema of adjacent extracranial soft tissues; right frontoparietal brain lesion and edema of adjacent parenchyma. She evolved with clinical instability and died after 61 days of hospitalization. Conclusion: A pattern of CSF hypotension was shown due to compression of the frontal horns of the lateral ventricles by the granulomas. There was a need for ventriculoperitoneal shunt, but patient had fatal complications.