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Dissertations / Theses on the topic 'Left ventricular function'

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1

PATTONERI, PAOLO. "Left ventricular myocardial performance." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2010. http://hdl.handle.net/2108/1163.

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Recentemente Tei e collaboratori, hanno proposto un nuovo indice Doppler-derivato in grado di valutare simultaneamente la funzione sistolica e diastolica. Questo indice di performance cardiaca (MPI), definito come la somma del tempo di contrazione isovolumetrica e tempo di rilasciamento isovolumetrico diviso per il tempo di eiezione ventricolare sinistro, è considerato di facile esecuzione, non dipendente dalla geometria ventricolare, non invasivo, riproducibile e indipendente dalla frequenza cardiaca e dalla pressione arteriosa. L’MPI ha dimostrato di avere un’importante utilità clinica. È i
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2

Maret, Eva. "Noninvasive Evaluation of Myocardial Ischemia and Left Ventricular Function." Doctoral thesis, Linköpings universitet, Klinisk fysiologi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-18315.

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The general aim of this thesis was, following the path of the ischemic cascade, to evaluate the feasibility of some new non-invasive techniques for the detection of myocardial ischemia, the extent of infarcted myocardium, and for the quantification of systolic left ventricular function. Reduced longitudinal myocardial velocity and displacement may be early signs of ischemia. We evaluated the diagnostic sensitivity and specificity of pulsed tissue Doppler for the detection of ischemia and scar during dobutamine stress testing and compared it with myocardial perfusion scintigraphy (SPECT) in pat
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3

Müller-Brunotte, Richard. "Diastolic heart function in hypertension-induced left ventricular hypertrophy /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-898-3/.

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4

Clarkson, Peter Bruce Mark. "Studies of left ventricular diastolic function inhealth and disease." Thesis, University of Dundee, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337397.

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5

Leung, Dominic Y. C. South Western Sydney Clinical School UNSW. "Exercise and left ventricular function in chronic mitral valve insufficiency." Awarded by:University of New South Wales. South Western Sydney Clinical School, 2002. http://handle.unsw.edu.au/1959.4/18808.

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The projects of this thesis examine the complex interaction between isotonic exercise, functional capacity, exercise-induced myocardial ischaemia, severity of regurgitation and left ventricular function in patients with significant chronic mitral regurgitation. The concept of left ventricular contractile reserve, i.e. the ability of the left ventricle to increase its contractility and decrease its end systolic volume with isotonic exercise, is explored. In patients with chronic isolated mitral regurgitation without coronary disease, isotonic exercise was associated with a slight decrease in le
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6

Jacob, Gary. "Quantifying regional left ventricular function using spatio-temporal tracking techniques." Thesis, University of Oxford, 1999. http://ora.ox.ac.uk/objects/uuid:051f5820-e6fb-4757-8669-b464fb050db9.

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Increasingly, diagnosis of cardiac disease, relies on computer processing of images to aid decision making. In this thesis, we use echocardiography, which is the most widely used cardiac imaging modality to study the motion of the left ventricle. Currently, clinical reporting of echocardiography examinations is operator-dependent and largely qualitative. Commercially available software does not track the left ven- tricle. Also, it does not provide quantification of regional function. This thesis establishes a framework for the quantitative regional analysis of left ven- tricular function. The
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7

Hedman, Anders. "Noninvasive evaluation of the effects of coronary artery bypass grafting on myocardial function /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-761-8/.

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8

Carlsson, Camilla. "Development of a thin, soft, single segment conductance catheter for monitoring left ventricular pressure and volume." Licentiate thesis, KTH, Physics, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-1441.

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<p>Knowledge of the leftventricular (LV) pressure-volume relation, along withparameters derived from this relation, have led to newpossibilities for the characterisation of cardiac pumpfunction, in both experimental studies and clinicalsettings.</p><p>The pressure-volume diagram is apowerful tool for visualising LV performance, but in order tobe clinically useful it is necessary to make plots continuouslyand on-line. The conductance catheter technique offers thispossibility. The conductance catheter system has experiencedgrowing interest among cardiologists, physiologists, surgeons,and anaesth
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9

Campbell, Stuart Gaylon. "The role of regulatory light chain phosphorylation in left ventricular function." Diss., [La Jolla] : University of California, San Diego, 2010. http://wwwlib.umi.com/cr/ucsd/fullcit?p3398511.

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Thesis (Ph. D.)--University of California, San Diego, 2010.<br>Title from first page of PDF file (viewed May 5, 2010). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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10

Shahgaldi, Kambiz. "Assessment of Left Ventricular Function and Hemodynamics Using Three-dimensional Echocardiography." Doctoral thesis, KTH, Medicinsk teknik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-12966.

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Left ventricular (LV) volumes and ejection fraction (EF) are important predictors of cardiac morbidity and mortality. LV volumes provide valuable prognostic information which isparticularly useful in the selection of therapy or determination of the optimal time for surgery. Two-dimensional (2D) echocardiography is the most widely used non-invasive method forassessment of cardiac function, 2D echocardiography has however several limitations inmeasuring LV volumes and EF since the formulas for quantifications are based on geometricalassumptions. Three-dimensional (3D) echocardiography has been a
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11

Ericsson, Anders B. "Cardioplegia and cardiac function : evaluated by left ventricular pressure-volume relations /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4138-6/.

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12

Hart, Emma C. J. "The physiological mechanisms underpinning post-exercise reductions in left ventricular function." Thesis, Brunel University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.443319.

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13

Armour, Sylvia. "The Effects of the Transcription Factor SRY1 on Left Ventricular Function." University of Akron / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=akron1208193131.

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14

Cameli, Matteo. "Mechanical and histological disturbances in advanced heart failure and cardiac transplantation." Doctoral thesis, Umeå universitet, Kardiologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-127295.

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The general purpose of this thesis is to establish capability and accuracy of speckle tracking echocardiography (STE) in assessing left atrial (LA), left ventricular (LV) and right ventricular (RV) function and their correlation with myocardial fibrosis, filling pressure and clinical outcomes in advanced heart failure (HF) patients before and after heart transplantation (HT). I demonstrated that HT recipients had impaired LV twist dynamics in the form of reduced rotation twist angle and untwist rate but time to peak twist was not different from the age matched controls and other cardiac surgic
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15

Waldenborg, Micael. "Echocardiographic measurements at Takotsubo cardiomyopathy : transient left ventricular dysfunction." Doctoral thesis, Örebro universitet, Institutionen för hälsovetenskap och medicin, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-35798.

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Takotsubo cardiomyopathy (TTC) is a disease characterized by transient left ventricular (LV) dysfunction and typical wall motion abnormalities in apical parts, without obvious signs of coronary influence. Due to its elusive natural cause and the lack of clarified pathology, further studies are needed. Thirteen patients presented with an episode of TTC, and referred to Örebro University Hospital (USÖ), were prospectively included and investigated by comparisons made at onset (acute phase) against at follow-up three months later (recovery phase). Including echocardiographic measurements, focused
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16

Mendes, Paulo Roberto Araújo 1968. "Função pulmonar e remodelamento ventricular esquerdo em indivíduos hipertensos = Lung function and left ventricular remodeling in hypertensive subjects." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312297.

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Orientador: Wilson Nadruz Júnior<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-25T05:29:30Z (GMT). No. of bitstreams: 1 Mendes_PauloRobertoAraujo_M.pdf: 976609 bytes, checksum: d5b069ade658cb23f9494d04dbbb255d (MD5) Previous issue date: 2014<br>Resumo: Pacientes hipertensos estão predispostos ao remodelamento do ventrículo esquerdo (VE) e frequentemente apresentam queda na função pulmonar quando comparados à população geral. Neste estudo investigamos a associação entre dados espirométricos e ecocardiográfic
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17

Ärnlöv, Johan. "Left Ventricular Function in Elderly Men : Metabolic, Hormonal, Genetic and Prognostic Implications." Doctoral thesis, Uppsala University, Department of Public Health and Caring Sciences, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2937.

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<p>Heart failure and left ventricular dysfunction are major causes of morbidity and mortality. In this thesis, metabolic, hormonal, genetic and prognostic aspects of echocardiographically determined left ventricular function were investigated in a fairly large longitudinal population-based study of men. The participants were examined both at age 50 and 70 years and were followed for mortality using the national cause-of-death registry.</p><p>Several factors associated with the insulin resistance syndrome predicted left ventricular systolic dysfunction independent of myocardial infarction, hype
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18

Neary, Paul. "Studies of sarcoplasmic reticulum function in rabbit and human left ventricular dysfunction." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300737.

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19

Young, Lesley Elissa. "Measurement of left ventricular function in anaesthetised horses using transoesophageal Doppler echocardiography." Thesis, University of Edinburgh, 1996. http://hdl.handle.net/1842/30053.

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Studies were undertaken using transoesophageal Doppler echocardiography to monitor left ventricular systolic function in anaesthetised horses. A 3.5 MHz transoesophageal probe was specifically developed in collaboration with Vingmed Sound for equine use. The indices of systolic function investigated were maximum acceleration of aortic blood flow (dv/dt<SUB>max</SUB>), maximum blood flow velocity, (V<SUB>max</SUB>), cardiac output (CO), left ventricular pre-ejection period (PEP) and left ventricular ejection time (ET). The feasibility of the technique was demonstrated in a group of 8 healthy Th
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20

Bilal, Dejan. "Evaluation of systolic and diastolic left ventricular function during exercise in athletes." Thesis, Malmö universitet, Fakulteten för hälsa och samhälle (HS), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-25669.

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Idrottshjärta är ett kardiovaskulärt tillstånd som uppträder under längre perioder av intensiv träning som orsakar strukturella, funktionella och elektriska förändringar hos hjärtat och är en fysiologisk anpassning som svar på ett ökat hemodynamiskt behov under fysisk ansträngning. De fysiologiska anpassningarna har dock blivit ett diagnostiskt dilemma att urskilja från de patologiska förändringarna såsom hypertrofisk kardiomyopati. Det finns därför ett behov av standardisering av kardiovaskulär screening hos idrottare för att upptäcka underliggande eller dolda kardiomyopatier som kan leda til
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21

Ibrahim, Michael. "Mechanical load regulates transverse-tubule structure and function in left ventricular cardiomyocytes." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/10486.

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Chronic mechanical load variation triggers a wide range of responses in the heart, a part of which includes cellular remodelling. Over the past 15 years, evidence has amassed that a part of this remodelling process involves changes to a sophisticated structure in the cell membrane, called the transverse (t)-tubule system. The t-tubules are a series of regular membrane invaginations, which contain a high density of ion channels responsible for local Ca2+ induced Ca2+ release (CICR). This thesis addresses the question of whether the t-tubule system can be said to be specifically load sensitive,
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22

McCormick, Matthew. "Ventricular function under LVAD support." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:0d49ba30-b508-4c69-9ba6-b398d4338c01.

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This thesis presents a finite element methodology for simulating fluid–solid interactions in the left ventricle (LV) under LVAD support. The developed model was utilised to study the passive and active characteristics of ventricular function in anatomically accurate LV geometries constructed from normal and patient image data. A non–conforming ALE Navier–Stokes/finite–elasticity fluid–solid coupling system formed the core of the numerical scheme, onto which several novel numerical additions were made. These included a fictitious domain (FD) Lagrange multiplier method to capture the interaction
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23

Digenio, Andres G. "Effects of exercise training on left ventricular function and exercise capacity in patients with coronary artery disease and varying degrees of left ventricular dysfunction." Doctoral thesis, University of Cape Town, 1999. http://hdl.handle.net/11427/26919.

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The medical profession has increased its acceptance of the benefits of exercise training for patients with uncomplicated coronary artery disease. Access to more modem technology and better management of this condition has led to an increase in the number of patients surviving acute coronary episodes . Some of these patients may have developed chronic asymptomatic left ventricular dysfunction and/or residual myocardial ischaemia, and could become potential candidates for cardiac rehabilitation if exercise training could induce physiological benefits without further deteriorating their condition
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24

Zhou, Yirong. "Left Ventricular Dynamics and Pulsatile Hemodynamics during Resuscitation of the Fibrillating Heart Using Direct Mechanical Ventricular Actuation." Wright State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=wright1547503362869157.

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25

Tamás, Éva. "Surgical treatment in chronic aortic regurgitation : Timing, results, prognosis and left ventricular function." Doctoral thesis, Linköpings universitet, Thoraxkirurgi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-12284.

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Chronic aortic regurgitation (AR) of varying degree affects 13% of men and 8.5% of women. In persons with severe AR, the expected length of life and its quality are influenced. Some individuals remain asymptomatic for a long period, due to effective compensatory mechanisms, but dysfunction of the left ventricle (LV) usually begins before symptoms appear and can be irreversible by then. This thesis addresses questions of LV function and optimal time for operation of patients suffering from chronic AR. Moreover, detailed echocardiographic studies of the anatomy of the normal aortic valve have be
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26

Fonseca, Carissa Grace. "Assessment of left ventricular diastolic function with three dimensional cardiac magnetic resonance imaging." Thesis, University of Auckland, 2004. http://hdl.handle.net/2292/5715.

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Measurement of diastolic left ventricular (LV) function is vitally important in the assessment of cardiac disease. However, only limited information on tissue function can be obtained with current clinical techniques. This Thesis developed and investigated novel parameters of both global and regional myocardial function, using cardiac magnetic resonance imaging (MRI) with three-dimensional tissue tagging. Multidirectional peak myocardial shortening strains and strain rates, as well as the peak systolic displacement and velocity of the mitral valve annulus plane (MVP), were considered as parame
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27

Marsch, Stephan Christoph Ulrich. "Effects and interactions of anaesthesia and myocardiac ischaemia on left ventricular diastolic function." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259937.

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28

Jugdutt, Bodh I. "Modification of left ventricular geometry and function during healing after acute myocardial infarction." Thesis, University of Glasgow, 2006. http://theses.gla.ac.uk/8341/.

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Increased left ventricular (LV) size and deformation of LV geometry are associated with LV dysfunction. Regional shape distortion (RSD), detected on two-dimensional echocardiography (2D-Echo) after acute myocardial infarction (MI), is associated with poor outcome. Two hypotheses were tested: i) early RSD of the asynergic infarct zone after MI is followed by progressive global LV dilatation, remodelling towards a spheroidal shape, and more LV dysfunction; and ii) the progressive remodelling of LV geometry spans the phases of early infarction and healing and may be modified by early and prolonge
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29

Moore, Alan D. "Reproducibility and sensitivity of Doppler echocardiographic indices of left ventricular function during exercise." Diss., Virginia Polytechnic Institute and State University, 1987. http://hdl.handle.net/10919/53648.

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The two most common methods used for the assessment of left ventricular function (LVF) are two-dimensional echocardiography and nuclear ventriculography. Recent technological advances have led to the development of an inexpensive, noninvasive alternative: the stand-alone continuous wave Doppler echocardiograph. The purposes cf this study were twofold: 1) to examine the repeatability of three Doppler measured indices of LVF during repeated exercise trials, and 2) to determine if induced changes in myocardial contractility would be reflected by changes in the Doppler indices. The Doppler indices
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Koh, Carline, and 許上冕. "Effects of right ventricular pacing and its interruption on left ventricular torsional mechanics and diastolic function in congenitalheart block." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45167199.

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31

Boët, Angèle. "Fonction ventriculaire gauche et pathologies du cœur droit : Intérêt de la cardiométrie électrique." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS301.

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La surcharge ventriculaire droite (VD), volumétrique ou barométrique, est devenue depuis quelques années un problème de santé publique chez les patients atteints de cardiopathie congénitale.Grâce aux progrès de la prise en charge de ces patients, cette population est grandissante avec des complications spécifiques. La défaillance ventriculaire gauche (VG) est une des complications les plus graves des pathologies de surcharge du VD.L’objectif de ce travail est de déterminer s’il existe des signes d’atteinte précoce du VG chez ces patients grâce à l’étude de 2 modèles chirurgicaux de surcharge d
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Fragata, Claudia da Silva. "Função atrial na miocardiopatia chagásica crônica." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-20052013-113004/.

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INTRODUÇÃO: A doença de Chagas tem patogênese não totalmente conhecida. Ao contrário das funções sistólica e diastólica do ventrículo esquerdo, a função do átrio esquerdo carece de informações. OBJETIVOS: Em portadores de doença de Chagas, com ou sem alterações eletrocardiográficas, com ou sem disfunção sistólica de ventrículo esquerdo, verificar se há diferença nos parâmetros de função atrial esquerda e se há correlação entre dados de função de átrio esquerdo e parâmetros ecodopplercardiográficos de função ventricular sistólica e diastólica de ventrículo esquerdo MÉTODOS: 85 indivíduos: 10 co
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33

Spotswood, Timothy C. "Echocardiographic changes of left ventricular size and function in a canine normovolaemic anaemia model." Diss., University of Pretoria, 2006. http://hdl.handle.net/2263/23732.

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The objective of this study was to non-invasively document the changes in echocardiographic variables of left ventricular size and function during acute normovolaemic anaemia. This model was developed as a pilot study with the purpose of providing baseline information to investigate the pathophysiology, and more specifically the effect on the heart, of canine babesiosis-induced anaemia. The study group comprised of 11 mature healthy Beagle dogs that weighed between 9 and 15 kg. Severe normovolaemic anaemia was induced over a 3-4 day period by serial bleeding while maintaining normovolaemia by
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34

Meyers, Brett Albert. "Feasibility of Echocardiographic Particle Image Velocimetry for evaluation of cardiac left ventricular filling function." Thesis, Virginia Tech, 2014. http://hdl.handle.net/10919/78159.

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Heart disease is one of the primary causes of morbidity and mortality for the adult population over the age of 65. Furthermore, ailments such as hypertension can affect as many as 50% of the adult population over the age of 45. If left untreated, these ailments eventually precipitate the onset of diastolic dysfunction and heart failure. Diastolic dysfunction is the alteration or impairment of performance in either the left or right ventricle of the heart. Although there has been a marked increase in study of this disease, there is still an apparent difficulty to diagnose patients. Flow visuali
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Ippisch, Holly M. "Associations Between Overweight and Left Ventricular Structure and Function in Overweight Children and Adolescents." University of Cincinnati / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1163795487.

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36

George, Robert Sobhi Bouchra. "The effects of left ventricular assist devices on myocardial function and cardiac nervous system." Thesis, Imperial College London, 2010. http://hdl.handle.net/10044/1/6419.

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Myocardial recovery in patients with non-ischaemic end-stage dilated cardiomyopathy can occur following left ventricular assist device (LVAD) and drug combination therapy. The effects of LVAD and drug combination therapy on the cardiac nervous system have not been adequately studied. It is well recognised that contractile reserve is decreased in heart failure patients who have an increased level of circulating norepinephrine secondary to failure of the myocardial norepinephrine transporter system. The aims of this study are to examine prospectively the outcome of using continuous-flow Heart Ma
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Eriksson, Jonatan. "Quantification of 4D Left Ventricular Blood Flow in Health and Disease." Doctoral thesis, Linköpings universitet, Avdelningen för kardiovaskulär medicin, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-98786.

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The main function of the heart is to pump blood throughout the cardiovascular system by generating pressure differences created through volume changes. Although the main purpose of the heart and vessels is to lead the flowing blood throughout the body, clinical assessments of cardiac function are usually based on morphology, approximating the flow features by viewing the motion of the myocardium and vessels. Measurement of three-directional, three-dimensional and time-resolved velocity (4D Flow) data is feasible using magnetic resonance (MR). The focus of this thesis is the development and app
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Balmain, Sean. "Studies of vascular function in patients with heart failure and either preserved or reduced left ventricular systolic function." Thesis, University of Glasgow, 2008. http://theses.gla.ac.uk/282/.

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Up to 50% of patients with the clinical syndrome of heart failure have preserved left ventricular systolic function (HF-PSF). Invasive studies utilising cardiac catheterisation have demonstrated that patients with HF-PSF have abnormalities of left ventricular (LV) relaxation and filling, or LV diastolic dysfunction. As a result, it has been proposed that LV diastolic dysfunction is the primary pathophysiological process in HF-PSF. However, population-based studies have shown that there is poor correlation between the presence of LV diastolic dysfunction and the presence of heart failure. This
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Nishijima, Yoshinori. "Effects of single-site and multi-site ventricular pacing on left and right ventricular mechanics and synchrony is there an optimal pacing sequence? /." Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1126717344.

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40

A'roch, Roman. "Left ventricular function's relation to load, experimental studies in a porcine model." Doctoral thesis, Umeå universitet, Anestesiologi och intensivvård, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-43605.

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Background: Loading conditions are recognized to influence ventricular function according to the Starling relationship for length/stretch and force.  Many modern echocardiographic parameters which have been announced as describing ventricular function and contractile status, may be confounded by uncontrolled and unmeasured load.  These studies aimed to measure the relation between four differ­ent types of assessments of ventricular dysfunction and degrees of load.  Study examined the ‘myo­cardial performance index’ (MPI).  Study II examined long axis segmental mechanical dyssynchrony.  Study I
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MacDonald, Kristin Ann. "Effect of ramipril on left ventricular mass, diastolic function, and neurohormones in feline hypertrophic cardiomyopathy /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2005. http://uclibs.org/PID/11984.

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42

Jashari, Haki. "The effect of pressure afterload due to aortic coarctation on left ventricular function in children." Doctoral thesis, Umeå universitet, Medicin, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-128126.

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Background: Coarctation of the aorta (CoA) is a congenital heart disease which represents a narrowing of the proximal descending aorta, hence increasing pressure afterload to the left ventricle (LV). Conventional treatment of native CoA is surgical repair, however potential recurrence or other related complications e.g. aortic rupture, heart failure and cerebrovascular events are common. Thus, lifelong follow-up of these patients is required. Echocardiography is the most patient’s friendly method to evaluate CoA and in particular its effect on LV function. Moreover, the novel speckle tracking
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Хірний, Дмитро Валерійович, Дмитрий Валерьевич Хирный, and Dmytro Valeriiovych Khirnyi. "Associations between human aldosterone synthase (CYP11B2) gene polymorphisms and left ventricular size, mass, and function." Thesis, Sumy State University, 2017. http://essuir.sumdu.edu.ua/handle/123456789/65603.

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Aldosterone has direct and indirect effects on the heart, and genetic variations in aldosterone synthesis could therefore influence the cardiac structure and function. Such variations might be associated with polymorphisms in the gene encoding aldosterone synthase (CYP11B2), the enzyme catalyzing the last steps of aldosterone biosynthesis.
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Hassan, Muhammad Yusuf. "Left ventricular function after ultra-distance triathlon : response is dependent on the cardiac loading conditions." Master's thesis, University of Cape Town, 2003. http://hdl.handle.net/11427/25803.

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The purpose of this thesis is to establish if there is any evidence to support the hypothesis that altered ventricular loading conditions after the cessation of exercise may cause "cardiac fatigue". The studies that have shown post-exercise "cardiac fatigue" have not controlled for either preload or afterload or both, before and after exercise. These studies may rather have identified the effects of alterations in peripheral vascular function on left ventricular function after prolonged exercise. The research study in this thesis is to evaluate if the loading conditions of the heart affect the
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Christopher, Bridgette A. "The Influence of Myofilament Protein Modification and Myocardial Insulin Resistance on Pathologic Left Ventricular Function." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1296007529.

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46

Dodd-o, Jeffrey M. (Jeffrey Michael). "The effects of coronary α₁-adrenergic stimulation on coronary blood flow and left ventricular function". Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc332773/.

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This study examines the α-adrenergic constrictor tone varies with intensity of exercise, the effects of coronary α1-adrenergic blockade on left ventricular contractile function and regional myocardial perfusion, and compares the effects of increasing coronary blood flow by removing α1-constrictor tone.
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47

Ohno, Nobuhisa. "Transplantation of cryopreserved muscle cells in dilated cardiomyopathy : Effects on left ventricular geometry and function." Kyoto University, 2004. http://hdl.handle.net/2433/147551.

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48

Gu, Haotian. "Left ventricular systolic function and myocardial wall stress in conditions predisposing to diastolic heart failure." Thesis, King's College London (University of London), 2017. https://kclpure.kcl.ac.uk/portal/en/theses/left-ventricular-systolic-function-and-myocardial-wall-stress-in-conditions-predisposing-to-diastolic-heart-failure(5ec32252-3057-4b7e-a345-00e669eab69d).html.

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Myocardial wall stress (MWS) is a crucial factor linked to myocardial hypertrophy, which can lead to heart failure, particularly heart failure with preserved ejection fraction (HFpEF). Shortening-deactivation of cardiac myocytes could provide a mechanism linking systolic to diastolic dysfunction whereby an impairment of early systolic ejection leads to sustained myocardial contraction, preserving overall ejection fraction at the expense of diastolic dysfunction. We formulated a novel index of first phase ejection fraction (EF1), the fraction of left ventricular volume ejected from the start of
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49

Hedberg, Pär. "Left ventricular systolic dysfunction in 75-year-old men and women : a community-based study of prevalence, screening and mitral annulus motion for diagnosis and prognostics /." Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5793.

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50

Fukuoka, Masahira. "Chordal "translocation" for functional mitral regurgitation with severe valve tenting : an effort to preserve left ventricular structure and function." Kyoto University, 2008. http://hdl.handle.net/2433/135784.

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