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Journal articles on the topic 'Lei n 12.690 de 2012'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

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1

Coelho, Iandra Maria Weirich da Silva. "As competências básicas no processo de ensino e aprendizagem de línguas: um estudo pautado no domínio comunicativo-digital (Basic competences in the teaching-learning process of language: a study based on the communicative-digital domain)." Revista Eletrônica de Educação 14 (May 7, 2020): 2820081. http://dx.doi.org/10.14244/198271992820.

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This paper presents a theoretical investigation with the objective of identifying the basic competences to be acquired and developed in the language teaching-learning process, especially in virtual contexts. The study herein presented, of bibliographic nature, evidences a discussion and reflections on the theme competences and the representativeness of the communicative-digital domain, in the production and sharing of information, in the written and oral modality. The results achieve three basic skills : interacion through Information and Communication Technologies, creation of digital content

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Cruz, Ana Cristina Juvenal da, Tatiane Cosentino Rodrigues, Denise Cruz, and Ivanilda Amado Cardoso. "Desafios curriculares no ensino superior: contribuições do Programa Abdias Nascimento (Curricular challenges in Higher Education: contributions from the Abdias Nascimento Program)." Revista Eletrônica de Educação 13, no. 2 (2019): 473. http://dx.doi.org/10.14244/198271993357.

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This article is dedicated to the development and presentation of the results of the first phase of implementation of the project "Knowledge, research and curricular innovations in teacher training for ethnic-racial diversity in higher education: questioning and contributions of ethnic-racial matrices and (NEAB / UFSCar), Brazil, linked to the Abdias Nascimento Academic Development Program, promoted by the Coordination for the Improvement of Higher Education Personnel (CAPES). The project aims to establish a transnational network of joint research between researchers in partnership with three i

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Malheiros, Ana Paula Dos Santos, Lahis Braga Souza, and Patrícia Peralta. "Tecnologias Digitais nas aulas de Matemática: um olhar para Diretoria de Ensino de São José do Rio Preto – SP (Digital Technologies in Mathematics classes: a look at the Board of Education of São José do Rio Preto – SP)." Revista Eletrônica de Educação 14 (February 1, 2020): 2841040. http://dx.doi.org/10.14244/198271992841.

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This paper presents results of research on the insertion of Digital Technologies in the Mathematics classes in the final years of Elementary School, in the Board of Education of São José do Rio Preto. For this purpose, we initially introduced the Project "Mapping of the use of information technologies in Mathematics classes in the state of São Paulo", to which these researches are linked. Subsequently, we dialogued with part of the pertinent literature about Digital Technologies in Mathematics classes, as well as with the continuing formation of teachers for the use of these technologies. Then

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Зайнулгабидинов, Эрик Ренатович, Юрий Алексеевич Игнатьев та Андрей Михайлович Петров. "ВЛИЯНИЕ ФИТОРЕМЕДИАЦИИ НА ПРОФИЛЬ УГЛЕВОДОРОДОВ НЕФТИ В АЛЛЮВИАЛЬНЫХ ДЕРНОВЫХ ПОЧВАХ". Российский журнал прикладной экологии, № 2 (25 червня 2021): 53–60. http://dx.doi.org/10.24852/2411-7374.2021.2.53.60.

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Фиторекультивация почв, загрязненных нефтью и нефтепродуктами, рассматривается как один из перспективных подходов в биотехнологии. Эффективность этого метода зависит от под- бора культур. Объектом исследования являлась загрязненная нефтью аллювиальная дерновая легкосуглинистая почва. Рассматривались варианты с начальным содержанием нефти 5.4 г/кг, 9.7 г/кг и 21.8 г/кг. В качестве фиторемедиантов использовались однодольные и двудольные растения ‒ пшеница яровая (Triticum vulgare L.) и горох посевной (Pisum sativum L). Газохроматографическим методом изучено изменение углеводородного состава посл

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Silva, Hellen Do Socorro de Araújo, Maura Pereira dos Anjos, Mônica Castagna Molina, and Salomão Antônio Mufarrej Hage. "Formação de professores do campo frente às “novas/velhas” políticas implementadas no Brasil: r-existência em debate (Rural Teacher Forming in face of “New/Old” Policies Implemented in Brazil: R-existence in debate)." Revista Eletrônica de Educação 14 (October 29, 2020): 4562146. http://dx.doi.org/10.14244/198271994562.

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The reflections presented in this article are part of the results produced by the research “Policies, Management and the Right to Higher Education: new modes of Regulation and trends under construction”, linked to the Universitas-Br Network, developed by Thematic Axis 7, whose research focuses on Rural Higher Education. The article provides analysis on teacher forming policies, focusing on the setbacks imposed on such policies, based on the approval of the “new” National Curriculum Guidelines for Initial Teacher Forming for Basic Education and the institution of the Common National Base for Ed

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Pertille, Carla Talita, Charles Costa Coelho, Dionatan Gerber, Álvaro Boson de Castro Faria, and Eleandro José Brun. "Estudo comparativo das diretrizes dos códigos florestais de 1965 e 2012." Extensão Rural 24, no. 2 (2017): 55. http://dx.doi.org/10.5902/2318179624644.

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A legislação ambiental brasileira tem uma base de elaboração com solidez elevada, porém, ainda apresenta limitações, exigindo da sociedade e das instituições, ações que elas, muitas vezes, não são capazes de cumprir. O objetivo do trabalho foi gerar um documento que proporcione um melhor entendimento da legislação ambiental brasileira, especificamente aos Códigos Florestais de 1965 (Lei n° 4.771/65) e 2012 (Lei n° 12.651/12). Diversas alterações foram feitas, principalmente em relação aos regimes de proteção de áreas de preservação permanente (APP) e reserva legal (RL). Dentre elas, o código a

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Baysal-Gurel, F., N. J. Taylor, J. Chatfield, and S. A. Miller. "First Report of Impatiens Downy Mildew Caused by Plasmopara obducens in Ohio." Plant Disease 96, no. 11 (2012): 1699. http://dx.doi.org/10.1094/pdis-06-12-0545-pdn.

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Single and double flowered impatiens (Impatiens walleriana Hook.f.) plants with symptoms of downy mildew were found in commercial greenhouses in Delaware, Wayne, and Holmes counties, Ohio, in April 2012. Plants were stunted and defoliated. Symptoms on remaining leaves included general chlorosis without discrete spots and downward curling of leaves. A downy white growth was observed on the lower surface of infected leaves. The disease was widespread in affected greenhouses and incidence in cvs. Shimmer Coral, Accent Mix, and Super Elfin was nearly 90%. The downy growth consisted of coenocytic m

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Topuz, Ruhan Deniz, Ozgur Gunduz, Cetin Hakan Karadag, Dikmen Dokmeci, and Ahmet Ulugol. "Endocannabinoid and N-acylethanolamide levels in rat brain and spinal cord following systemic dipyrone and paracetamol administration." Canadian Journal of Physiology and Pharmacology 97, no. 11 (2019): 1035–41. http://dx.doi.org/10.1139/cjpp-2019-0015.

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The cannabinoid system has been suspected to play a role in the mechanisms of action of dipyrone and paracetamol. Our purpose was to measure the local endocannabinoid and N-acylethanolamide levels in the brain and spinal cord of rats following dipyrone and paracetamol administration. Nociception was assessed 1, 5, and 12 h following drug injections in Wistar rats, using tail-flick and hot-plate tests. The antinociceptive effects of dipyrone (150, 300, and 600 mg/kg, i.p.) and paracetamol (30, 100, and 300 mg/kg, i.p.) were observed. After administration of the highest doses of dipyrone and par

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Fryc, Irena, and Przemyslaw Tabaka. "Outdoor Areas Lighting with LEDs – the Competition Between Scotopic Efficacy and Light Pollution." Photonics Letters of Poland 11, no. 3 (2019): 75. http://dx.doi.org/10.4302/plp.v11i3.924.

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In this paper the effect of typical outdoor LED lamps on star visibility index SVI was analyzed. For those lamps the spectral power distribution SPD, the nearest color temperature CCT [K] and efficacy n [lm/W] are provided. For given lamp, the SVI has been defined as ratio of its scotopic flux to scotopic flux created by full moon. The calculations shows that, the use of lamps with low CCT does not significantly affect the of the value SVI. Unfortunately from an economic point of view, those kind of lamps are less attractive in applications because of their low n. Full Text: PDF ReferencesC. R

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Adams, C., K. Strong, X. Zhao, et al. "The spring 2011 final stratospheric warming above Eureka: anomalous dynamics and chemistry." Atmospheric Chemistry and Physics Discussions 12, no. 8 (2012): 20033–72. http://dx.doi.org/10.5194/acpd-12-20033-2012.

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Abstract. In spring 2011, the Arctic polar vortex was stronger than in any other year on record. As the polar vortex started to break up in April, ozone and NO2 columns were measured with UV-visible spectrometers above the Polar Environment Atmospheric Research Laboratory (PEARL) in Eureka, Canada (80.05° N, 86.42° W) using the differential optical absorption spectroscopy (DOAS) technique. These ground-based column measurements were complemented by Ozone Monitoring Instrument (OMI) and Optical Spectrograph and Infra-Red Imager System (OSIRIS) satellite measurements, Global Modeling Initiative

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Andrade, Virginia Corrêa Santos, and Patrícia Francisca de Matos. "A EXPANSÃO CANAVIEIRA E AS ALTERAÇÕES EM ÁREAS DE PRESERVAÇÃO PERMANENTE EM RESERVATÓRIOS ARTIFICIAIS / THE SUGAR CANE CULTIVATION EXPANSION AND CHANGES IN PERMANENT PRESERVATIVE AREAS IN ARTIFICIAL WATER RESERVOIRS." Geo UERJ, no. 33 (December 31, 2018): e34109. http://dx.doi.org/10.12957/geouerj.2018.34109.

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A expansão do cultivo da cana-de-açúcar passou a ser justificada por se tratar de um dos pilares do crescimento econômico brasileiro, todavia, esse crescimento muitas vezes ocorre em detrimento das questões sociais e ambientais. O novo Código Florestal, sancionado pela Lei n° 12.651, em 25 de maio de 2012 reduziu drasticamente a proteção sobre as áreas do entorno dos reservatórios artificiais destinados a geração de energia elétrica com concessão anterior a 2001, passando a abranger somente a cota máxima de operação do reservatório. O objetivo deste trabalho consiste em compreender as alteraçõ

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Shore, Neal D., Luke T. Nordquist, Shilpa Gupta, et al. "Once-nightly (QD) dual CYP17-Lyase (L) inhibitor / androgen receptor (AR) antagonist VT-464 in patients with CRPC." Journal of Clinical Oncology 34, no. 2_suppl (2016): 343. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.343.

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343 Background: VT-464 is an oral, CYP17-L inhibitor and non-clinically an antagonist of the AR and its variants associated with clinical resistance to enzalutamide (ENZ) and abiraterone (AA). The safety, tolerability and initial PD effects (tumor responses, PSA and testosterone (T)-decreases) of QD VT-464 were evaluated in this Phase (Ph) 1/2 study (INO-VT-464-CL-004; NCT02361086). Methods: Chemotherapy-naïve (n = 20) M0 (n = 1) and M1 (n = 19) patients with CRPC prior to (TN, treatment-naïve; n = 9), or after AA (n = 6),ENZ (n = 3) or both (n = 2) were enrolled in sequential dose-cohorts of

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Bernardo, Cristiane Hengler Corrêa, Sergio Silva Braga Júnior, Mauricio Dias Marques, Silvia Cristina Vieira Gomes, and Timóteo Ramos Queiroz. "Percepção dos produtores rurais de Tupã, SP, sobre o processo de comunicação para execução da logística reversa de embalagens de agrotóxicos." Revista Observatório 1, no. 3 (2015): 242. http://dx.doi.org/10.20873/uft.2447-4266.2015v1n3p242.

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Disponível em: O artigo objetivou identificar a percepção de produtores rurais de Tupã/SP sobre a legislação que implantou e regulamenta a logística reversa de embalagens de agrotóxicos, bem como as informações que têm sobre sua obrigação. Buscou-se trazer elementos contidos na legislação e considerações de diversos autores, por meio de pesquisa bibliográfica, assim como foi aplicado um formulário com 19 questões, sobre o comportamento de 20 produtores rurais frente às informações relativas à devolução das embalagens vazias de agrotóxicos. As discussões revelam que cerca de 60% dos respondente

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LIMA, FABRÍCIO WANTOIL, CLAÚDIA PIMENTA LEAL, DIÓRGENES DE CASTRO FERREIRA RODRIGUES, and MATHEUS FELIPE DE OLIVEIRA ROSA. "A RESERVA LEGAL SOB A ÓTICA DO NOVO CÓDIGO FLORESTAL BRASILEIRO." Raízes no Direito 7, no. 1 (2018): 15–33. http://dx.doi.org/10.29287/2318-2288.2018v7i1.p15-33.

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Esta pesquisa tem como objetivo primordial a análise da nova legislação de cunho ambiental, Lei n. 12.651/12, mais especificamente o instituto da Reserva Legal, embasada pela doutrina e em congruência com o dispositivo legal. A presente pesquisa busca expor, de maneira clara, os aspectos pertinentes que norteiam e justificam o citado instituto por meio de uma vasta análise apoiada em revisão bibliográfica e no direito comparado. Visa-se esclarecer a importância da reserva legal para contribuir com a preservação do meio ambiente, além de demonstrar as falhas no dispositivo legal que causam cert

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Mello, Celso Antônio Bandeira de. "PARECER. IMPROBIDADE ADMINISTRATIVA. PROIBIÇÃO DE CONTRATAR COM O PODER PÚBLICO. TERMO INICIAL." Revista de Direito Administrativo e Infraestrutura - RDAI 4, no. 12 (2020): 307–11. http://dx.doi.org/10.48143/rdai/12.cabm.

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Quesito:1 Pena restritiva de direito concernente à proibição de contratar com o Poder Público ou receber benefícios ou incentivos fiscais ou creditícios, direta ou indiretamente, ainda que por intermédio de pessoa jurídica da qual seja sócio majoritário, pelo prazo de cinco anos, aplicada com fundamento na Lei Federal 8.492/92 (Lei de Improbidade Administrativa), tem como termo inicial para sua eficácia o trânsito em julgado da respectiva decisão judicial? A Consulente é empresa com notória e reconhecida expertise na prestação de serviços especializados de metodologias educacionais e cap

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Hapidin, Winda Gunarti, Yuli Pujianti, and Erie Siti Syarah. "STEAM to R-SLAMET Modification: An Integrative Thematic Play Based Learning with R-SLAMETS Content in Early Child-hood Education." JPUD - Jurnal Pendidikan Usia Dini 14, no. 2 (2020): 262–74. http://dx.doi.org/10.21009/jpud.142.05.

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STEAM-based learning is a global issue in early-childhood education practice. STEAM content becomes an integrative thematic approach as the main pillar of learning in kindergarten. This study aims to develop a conceptual and practical approach in the implementation of children's education by applying a modification from STEAM Learning to R-SLAMET. The research used a qualitative case study method with data collection through focus group discussions (FGD), involving early-childhood educator's research participants (n = 35), interviews, observation, document analysis such as videos, photos and p

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Silva, João Nunes da, Ronan Almeida Sousa, and Marlene Alves Borges. "Violência doméstica: análise e correlações do perfil educacional de autores e vítimas na cidade de arraias nos anos de 2012 a 2014." Revista Observatório 1, no. 3 (2015): 294. http://dx.doi.org/10.20873/uft.2447-4266.2015v1n3p294.

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Este estudo teórico/prático versa sobre a violência doméstica, problema de âmbito mundial. No Brasil conforme muitas pesquisas, tal violência tem inúmeras motivações, sobretudo cultural. A cidade de Arraias-TO não é exceção, sendo este tipo de violência fato recorrente naqueles lares, cidade objeto do estudo. Buscou-se evidenciar de forma sintética a problemática em nível mundial, nacional e por fim, em uma esfera mais detalhada, nos lares arraianos. O objetivo deste estudo foi compreender a violência doméstica a partir da aplicação e efetividade da Lei Maria da Penha correlacionando os fatos

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Mauro, Michael, Jerald Radich, Jorge E. Cortes, et al. "Single-Arm, Open-Label, Multicenter Study Of Deep Molecular Response (MR4.5) With Nilotinib In Adult Patients (pts) With Newly Diagnosed Philadelphia Chromosome–Positive Chronic Myeloid Leukemia In Chronic Phase (CML-CP): ENESTnext Study Update." Blood 122, no. 21 (2013): 4015. http://dx.doi.org/10.1182/blood.v122.21.4015.4015.

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Abstract Background Pivotal treatment-free remission (TFR) trials require prolonged deep molecular response (MR), often MR4.5, for study entry (Mahon et al. 2010), which has led to increasing focus on MR4.5 as a treatment goal for pts with CML-CP. New tyrosine kinase inhibitors (TKIs), such as nilotinib, more potently inhibit BCR-ABL and elicit significantly deeper and faster MRs than imatinib (Larson et al. 2012), requiring more sensitive techniques to monitor residual disease. In ENESTnext (registered as NCT01227577), MR was evaluated using standard reverse transcriptase quantitative polymer

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Lee, Sanghoon, Changhong Yin, Janet Ayello, Erin Morris, Carmella van de Ven, and Mitchell S. Cairo. "Downregulation of DLEU1 Significantly Shortened Survival in a Rituximab-Treated DLEU1 Knockout Human Burkitt Lymphoma (BL) Xenograft NSG Mouse Model: DLEU1 May Act As a Tumor Suppressor Gene in Pediatric BL." Blood 126, no. 23 (2015): 3656. http://dx.doi.org/10.1182/blood.v126.23.3656.3656.

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Abstract BACKGROUND: Burkitt lymphoma (BL) is the most common histological subtype of non-Hodgkin lymphoma (NHL) in children and adolescents (Cairo et al., Blood, 2007; Miles/Cairo, BJH, 2012). We have previously identified secondary chromosomal aberrations in 70% of pediatric BL patients (PBL) with a C-MYC gene rearrangement (Poirel/Cairo et al., Leukemia, 2009). Specifically, we identified significantly inferior event free survival (EFS) and overall survival in children and adolescents with a specific loss of the 13q14.3 locus (Poirel/Cairo et al., Leukemia, 2009; Nelson/Cairo/Sanger et al.,

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Farmer, Kristine, Jeff Allen, Malak Khader, Tara Zimmerman, and Peter Johnstone. "Paralegal Students’ and Paralegal Instructors’ Perceptions of Synchronous and Asynchronous Online Paralegal Course Effectiveness: A Comparative Study." International Journal for Educational and Vocational Studies 3, no. 1 (2021): 1. http://dx.doi.org/10.29103/ijevs.v3i1.3550.

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To improve online learning pedagogy within the field of paralegal education, this study investigated how paralegal students and paralegal instructors perceived the effectiveness of synchronous and asynchronous online paralegal courses. This study intended to inform paralegal instructors and course developers how to better design, deliver, and evaluate effective online course instruction in the field of paralegal studies.Survey results were analyzed using independent samples t-test and correlational analysis, and indicated that overall, paralegal students and paralegal instructors positively pe

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Romanus, Dorothy, Mehul Jhaveri, Richard Labotka, Henry Henk, and Brian Seal. "Treatment Patterns and Outcomes Among Patients Who Initiate Therapy for Relapsed/Refractory Multiple Myeloma (RRMM) in Routine Care." Blood 126, no. 23 (2015): 4515. http://dx.doi.org/10.1182/blood.v126.23.4515.4515.

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Abstract Background Multiple myeloma (MM) is the second most common hematologic cancer in adults. Novel agents, including thalidomide, bortezomib, and lenalidomide, have led to improved overall survival (OS) in MM, but the disease remains generally incurable with the majority of patients inevitably relapsing after front-line therapy (FLT). In a multi-center observational analysis of 383 MM patients (treated between 2007 and 2010), median progression-free survival (PFS) and OS from treatment after first relapse were 13 and 35 mos (Durie ASCO 2012; abs 8095). According to NCCN guidelines, retrea

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Kenter, Gemma, Stefano Greggi, Ignace Vergote, et al. "Results from neoadjuvant chemotherapy followed by surgery compared to chemoradiation for stage Ib2-IIb cervical cancer, EORTC 55994." Journal of Clinical Oncology 37, no. 15_suppl (2019): 5503. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.5503.

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5503 Background: Conflicting evidence on the value of neoadjuvant chemotherapy followed by surgery compared to concomitant chemoradiation in Stage IB2-IIB cervical carcinoma led to this multinational multicenter trial. As the trial is approaching completion of its follow-up, preliminary results are presented. Methods: Between May 2002 and June 2014 a total of 620 patients with FIGO stage Ib2-IIb were randomized between neoadjuvant chemotherapy followed by surgery (NACTS, arm 1, N=311) with standard concomitant chemoradiotherapy (CCRT, arm 2, N=309) . In arm 1, radical hysterectomy was required

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Robergs, R. A., O. Appenzeller, C. Qualls, et al. "Increased endothelin and creatine kinase after electrical stimulation of paraplegic muscle." Journal of Applied Physiology 75, no. 6 (1993): 2400–2405. http://dx.doi.org/10.1152/jappl.1993.75.6.2400.

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The purpose of this study was to assess changes in creatine kinase (CK) and endothelin (ET) in individuals with spinal cord injury (SCI) after computerized functional electrical stimulation leg ergometry (CFES LE). Eight subjects (7 male and 1 female) with complete spinal cord lesions (C7 to L1) completed zero-loaded CFES LE tests at baseline, after 3, 6, and 12 wk of CFES LE training (30 min, 3 times/wk), and also after detraining (DT) (n = 5). Venous blood samples were drawn 24, 48, and 72 h after CFES LE for measurement of ET and CK. The CK response was largest (peak CK) 72 h after baseline

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Zueva, Elena V., Sergey L. Belopukhov, and Ravil F. Baybekov. "Investigation of the quality of seeds of Anethum graveolens varieties Gribovsky and Lesnogorodsky by method of thermal analysis." Butlerov Communications 64, no. 12 (2020): 45–51. http://dx.doi.org/10.37952/roi-jbc-01/20-64-12-45.

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The paper presents data on the study of the chemical composition of dill (Anethum graveolens L) using foliar treatment of vegetative plants with the growth-regulating agent Nicosulfuron [2-(4,6-dimethoxypyrimidin-2-ylcarbomoyl-sulfamoyl) -N,N-dimethylnicotinamide]. Field experiments were carried out at the agrobiological station of the Humanitarian and Technological University of the city of Orekhovo-Zuevo, Moscow Region in 2016-2018. The soil of the experimental plots is sod-podzolic medium loamy. Plants were treated with a solution of Nicosulfuron with a concentration of 0.1 g/l according to

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Pond, Dimity, Karen Mate, Nigel Stocks, et al. "Effectiveness of a peer-mediated educational intervention in improving general practitioner diagnostic assessment and management of dementia: a cluster randomised controlled trial." BMJ Open 8, no. 8 (2018): e021125. http://dx.doi.org/10.1136/bmjopen-2017-021125.

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ObjectiveTest effectiveness of an educational intervention for general practitioners (GPs) on quality of life and depression outcomes for patients.DesignDouble-blind, cluster randomised controlled trial.SettingGeneral practices in Australia between 2007 and 2010.ParticipantsGeneral practices were randomly allocated to the waitlist (n=37) or intervention (n=66) group, in a ratio of 1:2. A total of 2030 (1478 intervention; 552 waitlist) community-dwelling participants aged 75 years or older were recruited via 168 GPs (113 intervention; 55 waitlist).InterventionsA practice-based academic detailin

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Slejko, Julia F., Dorothy Romanus, Daisuke Goto, et al. "Patterns and Determinants of Cancer-Directed Drug Therapy in Medicare Beneficiaries with Multiple Myeloma." Blood 128, no. 22 (2016): 5926. http://dx.doi.org/10.1182/blood.v128.22.5926.5926.

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Abstract Introduction: The introduction of novel therapies for multiple myeloma (MM) such as immunomodulatory drugs and proteasome inhibitors has led to considerable improvements in clinical outcomes, but the disease remains incurable. Both conventional and to a lesser extent novel therapies come with toxicity and treatment decisions need to be individualized based on factors such as age and comorbidities. Little is known about the frequency of drug therapy use in MM in real-world clinical practice. Objective: This study aimed to assess the prevalence of, and determinants associated with cance

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Adams, C., K. Strong, X. Zhao, et al. "The spring 2011 final stratospheric warming above Eureka: anomalous dynamics and chemistry." Atmospheric Chemistry and Physics 13, no. 2 (2013): 611–24. http://dx.doi.org/10.5194/acp-13-611-2013.

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Abstract. In spring 2011, the Arctic polar vortex was stronger than in any other year on record. As the polar vortex started to break up in April, ozone and NO2 columns were measured with UV-visible spectrometers above the Polar Environment Atmospheric Research Laboratory (PEARL) in Eureka, Canada (80.05° N, 86.42° W) using the differential optical absorption spectroscopy (DOAS) technique. These ground-based column measurements were complemented by Ozone Monitoring Instrument (OMI) and Optical Spectrograph and Infra-Red Imager System (OSIRIS) satellite measurements, Global Modeling Initiative

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Журавльова, Олена, Лариса Засєкіна та Олександр Журавльов. "Академічна прокрастинація в іноземних студентів бакалаврату в умовах лінгвокультурної інтеграції". East European Journal of Psycholinguistics 6, № 1 (2019): 82–93. http://dx.doi.org/10.29038/eejpl.2019.6.1.zhu.

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У статті обґрунтовано актуальність вивчення чинників акультурації та мовної адаптації у контексті дослідження специфіки прояву прокрастинації іноземними студентами. Висвітлено особливості операціоналізації вказаних понять у сучасній науковій літературі. Вибірку дослідження склали іноземні студенти (n=41), які навчаються за освітнім рівнем «бакалавр» у двох вищих навчальних закладах України. Результати кореляційного аналізу свідчать про позитивний взаємозв’язок прокрастинації із загальним рівнем прояву стресу акультурації (r = 0.43, p<0,01), а також такими його аспектами як акультураційний с

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Stauder, S., and P. M. Peloso. "POS1125 DUAL ENERGY CT HAS PROGNOSTIC VALUE IN GOUT BEYOND STANDARD CLINICAL MEASURES: A BEST EVIDENCE SYNTHESIS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 841.2–842. http://dx.doi.org/10.1136/annrheumdis-2021-eular.872.

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Background:Dual Energy CT Scan (DECT) can detect monosodium urate crystal deposits in multiple tissues. EULAR gout guidelines (Richette, 2020) recognized the value of DECT in making a clinical diagnosis when joint aspiration is difficult. DECT shows crystal deposits in almost 50% of gout patients without tophi (Dalbeth, 2017). Tophi are known to predict all-cause and cardiovascular mortality (Vincent 2017, Perez-Ruiz 2013) and it is plausible that DECT could as well. A prognostic measure should be reliable and valid. DECT validity would be evident for death, disability and distress.Objectives:

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Perea, Nayane Moreno, and Géssica Priscila Ramos. "Construção do direito da criança pequena à educação no Brasil: história a partir do estado (Construction of the little child's right to education in Brazil: history from the state)." Revista Eletrônica de Educação 14 (May 11, 2020): 3443082. http://dx.doi.org/10.14244/198271993443.

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This article discusses the ways of building the right to education of young child in Brazil, with reference to the State 's participation in this process. Based on a bibliographical analysis, it verified the predominance of three central periods in this history, being: that of an absent State, which bequeathed the child's education to family, private, community, religious and charitable initiatives; the one of a conservative State, that acted in the area notably from normative actions and of inspection of private institutions, for tutelage and control of the childhood, under a care bias, hygie

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Mattos, Ubirajara Aluizio de Oliveira, Paula Raquel Dos Santos, and Dulciléia De Souza Rocha. "SERVIÇO DE ATENÇÃO À SAÚDE E SEGURANÇA DO CATADOR DE MATERIAIS RECICLÁVEIS EM COOPERATIVAS." Revista Internacional de Ciências 11, no. 1 (2021): 78–96. http://dx.doi.org/10.12957/ric.2021.51532.

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As relações de trabalho nas organizações autogestionárias, regulamentadas pela Lei Federal n° 12.690 de 19 de julho de 2012, são diferentes das organizações regidas pela Consolidação das Leis do Trabalho e pelo Regime Jurídico Único. As organizações autogestionárias necessitam de um serviço de saúde e segurança do trabalhador adaptado às suas características, capacidades e limitações. O artigo tem como objetivo propor um modelo de serviço de atenção à saúde e segurança do trabalhador, voltado para cooperativas de catadores de materiais recicláveis. Baseado em um perfil socioeconômico de catado

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Gapanovich, Mikhail V., Natalia A. Tikhonina, Tatiana S. Kokovina, et al. "Influence of Bath Temperature on Structural, Optical and Electrical Properties of Cadmium Sulfi de Thin Films Prepared by Chemical Bath Deposition." Kondensirovannye sredy i mezhfaznye granitsy = Condensed Matter and Interphases 21, no. 4 (2019): 490–97. http://dx.doi.org/10.17308/kcmf.2019.21/2360.

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Abstract. The effect of bath temperature (60-90 °C) on structural, optical and electrical propertiesof CdS thin films deposited by chemical bath deposition (CBD) at a constant precursorconcentration and deposition time was studied. From the XRD analysis, it was found that thestructure of CdS thin fi lms varied with temperature. At lower temperature hexagonal structurewas dominated while at high temperature, the cubic structure was prominent. The band gap ofthe as-prepared CdS thin fi lms was calculated from the UV-Vis spectroscopic data, and it wasfound to be decreased with the increase of tem

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Guerra, Lenin Cavalcanti Brito, Rita Maria Correia Ferraz, and Jássio Pereira Medeiros. "Evasão na educação superior de um instituto federal do nordeste brasileiro (Evasion in higher education of a federal institute of the brazilian northeast)." Revista Eletrônica de Educação 13, no. 2 (2019): 533. http://dx.doi.org/10.14244/198271992529.

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In Federal Institutes (Brazil), the annual evasion vary from 24% to 26%, which may reach, after three years, more than 70% of its entrants. This reality has been detected in the Technology in Public Management Degree Course offered by a Federal Institute of Education, Science and Technology in the Brazilian northeast, where, in some classes, evasion rates has reached up to 77%. Despite this scenario, the accumulated systematized knowledge about the evasion in Brazil is still scarce, especially how it affects Technology Degree Courses. As a means of contributing to this kind of research, this w

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Bastos, Stephanie Freires, and Mario Lopes Amorim. "A QUALIFICAÇÃO PROFISSIONAL COMO POSSIBILIDADE DE RESSOCIALIZAÇÃO DOS JOVENS EM CUMPRIMENTO DE MEDIDAS SOCIOEDUCATIVAS." Revista Labor 2, no. 18 (2018): 6. http://dx.doi.org/10.29148/labor.v2i18.33500.

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Este artigo tem por objetivo contribuir para a discussão de medidas político-pedagógicas direcionadas a jovens considerados infratores, as quais têm por finalidade assegurar ao jovem o direito à inserção no mundo do trabalho por meio da educação voltada à profissionalização qualificada. Para reforçar as diretrizes do ECA, bem como ampliar a aplicabilidade das medidas socioeducativas para jovens infratores, foi sancionada a Lei n° 12.594, de 12 de janeiro de 2012, que institui o SINASE, criado com a finalidade de regulamentar a execução de medidas pedagógicas destinadas a adolescentes praticant

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Nakaseko, Chiaki, Naoto Takahashi, Kaichi Nishiwaki, Hitoshi Ogasawara, and Hisashi Wakita. "Switching to Nilotinib Are Associated with Deeper Molecular Responses in Chronic Myeloid Leukemia with Persistent Residual Disease on Long-Term Imatinib Therapy: STAT1 Trial in Japan." Blood 126, no. 23 (2015): 4032. http://dx.doi.org/10.1182/blood.v126.23.4032.4032.

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Abstract Introduction: Nilotinib is a second-generation TKI that exhibits significant efficacy as first- or second-line treatment in patients with CML. Superior rates of deeper molecular responses were achieved with nilotinib vs. imatinib in patients newly diagnosed with CML in chronic phase in the ENESTnd trial. In addition, the 24-month analysis of the ENESTcmr study demonstrated that switching to nilotinib after a minimum of 2 years on imatinib led to increased rates of MR4.5 by 24-month vs. remaining on imatinib (42.9% on nilotinib vs. 20.8% on imatinib). Although our CMR study revealed th

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Mraz, Marek, Karla Malinova, Sarka Pavlova, et al. "Detail Characterization of 22q11 Deletion and Mir-650 Role in CLL Patients." Blood 114, no. 22 (2009): 1231. http://dx.doi.org/10.1182/blood.v114.22.1231.1231.

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Abstract Abstract 1231 Poster Board I-253 Background Chromosomal abnormalities are present in the majority of CLL cases (&gt;80%) and recently, a novel deletion of 22q11 was described in CLL patients. This locus encodes lambda immunoglobulin light chain (IgL) subgenes and several protein-coding genes, which distinguishes IgL from kappa Ig or heavy Ig locus. Gunn et al. (2008) previously characterized the minimally deleted region of 22q11 in CLL as 0,34Mb (containing PRAME, ZNF280A, ZNF280B, GGTLC2) and described the PRAME as a candidate gene with prognostic impact in CLL. Interestingly, th

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Karnowski, Karol Marian, Ewa Mączyńska, Maciej Nowakowski, Bartłomiej Kałużny, Ireneusz Grulkowski, and Maciej Wojtkowski. "Impact of diurnal IOP variations on the dynamic corneal hysteresis measured with air-puff swept-source OCT." Photonics Letters of Poland 10, no. 3 (2018): 64. http://dx.doi.org/10.4302/plp.v10i3.848.

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The deformation amplitudes measured with air-puff OCT are sensitive to both (intraocular pressure) IOP and biomechanical properties of the cornea. Analysis of the amplitudes of corneal deformation is challenging due to interrelation of IOP and corneal biomechanics. In this study, we used natural diurnal IOP fluctuations to investigate corneal deformations in a number of subjects whose eyes were measured multiple times during a day. The results of analysis, based on corneal hysteresis, revealed a corneal hysteresis parameter, which remains constant during a day for each individual eye. We hypot

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Auerbach, Martin S., Edward M. Wolin, Val Nassiri, Per Broberg, and Ghassan El-Haddad. "Safety of 177Lu-DOTATATE in patients with advanced neuroendocrine tumors: Data from a U.S. expanded access program." Journal of Clinical Oncology 38, no. 15_suppl (2020): 4604. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.4604.

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4604 Background: The NETTER-1 clinical trial showed that peptide receptor radionuclide therapy (PRRT) with 177Lu-DOTATATE increased progression-free survival in patients with somatostatin-receptor-positive advanced midgut neuroendocrine tumors (NETs) compared with high-dose octreotide long-acting repeatable, and was associated with few serious adverse events (AEs). To assess the safety profile of 177Lu-DOTATATE in a real-world population, we analyzed safety data from a US expanded access program (NCT02705313). Methods: Patients had inoperable, histologically proven, somatostatin-receptor-posit

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Choy, E., V. Bykerk, Y. Lee, et al. "SAT0102 NONINFLAMMATORY PAIN IS A FREQUENT PHENOMENON IN RHEUMATOID ARTHRITIS AND RESPONDS WELL TO TREATMENT WITH SARILUMAB." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 984.1–985. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2015.

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Background:Inflammation is clearly a key driver of pain in rheumatoid arthritis (RA). However, in some patients the level of pain exceeds what would be expected based on the amount of synovitis observed, which may indicate the presence of noninflammatory pain (NIP). Interleukin-6 (IL-6) has been shown in animal models to increase sensitization to pain and may play a role in NIP.Objectives:To assess the effect of sarilumab, a human IL-6 receptor inhibitor approved for the treatment of adults with moderate to severely active RA, on NIP and disease activity, stratified by baseline (BL) NIP status

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Leong, Tze Shin, Sen Mui Tan, Lee Ping Chew, et al. "Treatment Outcome and a Practical 10-Point Prognostic Index in Adult Patients with Non-M3 Acute Myeloid Leukemia: A Retrospective, Multicenter Study in Malaysia." Blood 134, Supplement_1 (2019): 2606. http://dx.doi.org/10.1182/blood-2019-126656.

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Background: Literature on Acute Myeloid Leukemia (AML) survival and prognostic factors were often derived from strict trial studies from developed country. A simple yet practical prognosis index has not been developed and tested in resource limited setting such as Malaysia. We described the treatment outcome and designed a 10 point prognostic index to predict survival of adult AML (non-M3) in real clinical practice in Malaysia. Methods: Data were retrospectively collected and analyzed from all adults with AML diagnosed and treated from 2007 to 2017 in three main hematology centers in Malaysia,

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Quiroga, Josué, Omar Flor, Santiago Solórzano, and José Calahorrano. "Design of a Videolaryngoscope with sensor and pressure alert." Athenea 2, no. 3 (2021): 21–27. http://dx.doi.org/10.47460/athenea.v2i3.13.

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This work presents the design and construction of a laryngoscope model with camera vision that has a vibrating device to alert the medical specialist when the force exerted causes possible damage to the patient's airway during the intubation process. Design and fabrication considerations are described using Cast Material Position (FFD). The design is validated with the use of a high-fidelity simulator, the performance is compared with commercial models and the criteria of specialists are taken into account to improve all the necessary aspects. The model presented a great functional advantage,

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Maharti, Hastin Melur, and Winarini Wilman Mansoer. "HUBUNGAN ANTARA KEPUASAN PERNIKAHAN, KOMITMEN BERAGAMA, DAN KOMITMEN PERNIKAHAN DI INDONESIA." JKKP (Jurnal Kesejahteraan Keluarga dan Pendidikan) 5, no. 1 (2018): 70–81. http://dx.doi.org/10.21009/jkkp.051.07.

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This research is aimed to discover the interrelation between marital satisfaction, religiouscommitment and marital commitment globally and based on its types, personal, moral, andstructural. The sampling of the research is 315 persons, with age 20 until 58 years old. The resultof the research shows there is a significant correlation between marital satisfaction and maritalcommitment, religious commitment and marital commitment, marital satisfaction together withreligious commitment and marital commitment. It is also discovers that marital commitmentinfluences personal commitment and moral comm

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Nascimento, Christian Lindberg L. do. "A pedagogia histórico-crítica como abordagem metodológica para o ensino da filosofia." Trilhas Filosóficas 12, no. 1 (2019): 181–201. http://dx.doi.org/10.25244/tf.v12i1.31.

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Resumo: Os estudos historiográficos e filosóficos desenvolvidos por Dermeval Saviani têm apontado para a aplicação do materialismo-histórico-dialético ao debate educativo nacional. Neste sentido, a formação humana emerge como tema central das investigações educacionais, na qual se busca a superação da relação exploratória entre o Capital e o trabalho, marcada pela alienação e opressão do homem pelo homem. Como defende Saviani, "superar a alienação para alcançar-se o pleno desenvolvimento da individualidade livre e universal: essa é a perspectiva da sociedade comunista em Marx." (SAVIANI, 2015a

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Santos, Pedro Henrique Araújo dos, and Juliana Kelly Dantas da Silva. "A importância da rede de juventudes do Seridó na participação social dos jovens no município de Caicó-RN." Trilhas Filosóficas 10, no. 1 (2018): 131–60. http://dx.doi.org/10.25244/tf.v10i1.3066.

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Resumo: Nos dias atuais, percebemos que muitas são as dificuldades para a organização da juventude e a participação política nos espaços de poder e decisão existentes na sociedade. Em muitos dos espaços políticos os jovens não se sentem representados, nem tem oportunidades de defender seus interesses. Nesse contexto, percebe-se a ausência de formação política e oportunidades de participação do jovem na sociedade. Nessa perspectiva, esta pesquisa está pautada no levantamento de elementos da participação social, cultura política dos jovens e da trajetória de organização da Rede de Juventudes do

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Patel, Manish R., Guillermo Garcia-Manero, Ronald Paquette, et al. "Phase 1 Dose Escalation and Expansion Study to Determine Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the BET Inhibitor FT-1101 As a Single Agent in Patients with Relapsed or Refractory Hematologic Malignancies." Blood 134, Supplement_1 (2019): 3907. http://dx.doi.org/10.1182/blood-2019-124741.

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Background: BET inhibitors have demonstrated therapeutic potential in hematologic malignancies; however low therapeutic margins have limited clinical development. FT-1101 (also known as CC-95775) is a BET bromodomain inhibitor of all 4 BET family members BRD4, BRD2, BRD3, and BRDT (Kd ≤20 nM) and shows additional activity towards several non-BET bromodomain proteins (including CECR2 and BRD9). In vitro, FT-1101 displayed potent anti-proliferative activity across a broad panel of human leukemia cell lines. In xenograft and syngeneic models, FT-1101 achieved superior tumor growth inhibition (inc

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Leão, Andreza Marques de Castro, Rita De Kássia Cândido Carneiro, and Ana Maura Martins Castelli Bulzoni. "As necessidades formativas do professor iniciante: os desafios da diversidade na escola (The formative needs of the beginning teacher: the challenges of diversity at school)." Revista Eletrônica de Educação 14 (October 9, 2020): 4217123. http://dx.doi.org/10.14244/198271994217.

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e4217123This article aims to discuss the issue of diversity present in school institutions and the need for work aimed at valuing the masses excluded by society, emphasizing the question of the rights of black people and women. Based on the need for work to overcome racism and sexism, we highlight the relevance of continuing training for beginning teachers, as they leave the universities and face the reality of schools, experiencing the “shock of the real”. Our proposal is for teachers to be prepared for a more inclusive performance, developing a critical and accurate look at the role they pla

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Gomes, Marineide De Oliveira, and Daniel Arias Vazquez. "Projeto acadêmico e gestão democrática no ensino superior público: o caso da UNIFESP- campus Guarulhos (Academic Project and democratic management in public higher education: the case of UNIFESP – Guarulhos campus)." Revista Eletrônica de Educação 14 (May 14, 2020): 3347086. http://dx.doi.org/10.14244/198271993347.

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This work presents an experience report about the academic management (2013-2017) in the Human Sciences´campus of the Federal University of São Paulo (Unifesp), based in Guarulhos/SP, Brazil. We highlight three important aspects involved in the consolidation process of the campus and which we seek to problematize in the text: i) a perspective of democratic management, the incentive to the ecology of knowledge and the expansion of the social appropriation of the campus in its territory; ii) the limits and possibilities of collective production Political Pedagogical Project of the campus, with t

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Silva, Fátima Maria Rodrigues Chagas da, and Laélia Portela Moreira. "Professores iniciantes em escolas de periferia: desafios da “sobrevivência” na sala de aula (Beginning teachers in periphery schools: challenges of “survival” in the classroom)." Revista Eletrônica de Educação 14 (October 9, 2020): 4183122. http://dx.doi.org/10.14244/198271994183.

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e4183122The beginning of the teaching practice is a phase of utmost importance for the constitution of the teacher's identity and it generally presents itself as being full of challenges. This article presents the results of a research that analyzed the main difficulties of the initial years of teaching, from the point of view of novice teachers teaching for the Municipality of Duque de Caxias (Brazil), complemented with testimonies of the pedagogical team. Concepts such as "Reality Shock" and "Professional Development" gave theoretical support to the research. The methodology included analysi

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Pratz, Keith W., Courtney D. DiNardo, Martha L. Arellano, et al. "Outcomes after Stem Cell Transplant in Older Patients with Acute Myeloid Leukemia Treated with Venetoclax-Based Therapies." Blood 134, Supplement_1 (2019): 264. http://dx.doi.org/10.1182/blood-2019-127251.

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BACKGROUND: Allogenic hematopoietic stem cell transplant (SCT) is a potentially curative option for patients with acute myeloid leukemia (AML). However, patients who are older, are ineligible for intensive chemotherapy due to significant comorbidities, or have biologically aggressive and refractory disease are not often considered as viable SCT candidates. Venetoclax, a highly selective, potent BCL-2 inhibitor that induces apoptosis in AML cells, has resulted in high rates of durable remission when combined with hypomethylating agents (HMAs) or low dose cytarabine (LDAC), in older patients tra

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Brennand, Edna Gusmão de Góes, and Alexsander De Carvalho Silva. "A universidade e a produção do conhecimento sobre violações aos direitos humanos (University and the knowledge production about human rights violations)." Revista Eletrônica de Educação 14 (October 29, 2020): 4488149. http://dx.doi.org/10.14244/198271994488.

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e4488149This paper discusses the role of the Universities in defense of life, democracy and rule of the law, and science as a generator of spaces of resistance in day-to-day and as powerful tool for unmasking of authoritarianism. In this context, it presents the results of the research on the role of perpetrators of human rights violations during Brazilian military dictatorship. The investigation was carried out at the Federal University of Paraíba, by the Interdisciplinary Network for the Study of Violence–RIEV, with the participation of the University of València, in Spain. For this study, 3

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