Academic literature on the topic 'Leishmaniose – Immunologie'

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Journal articles on the topic "Leishmaniose – Immunologie"

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Toepp, Angela J., and Christine A. Petersen. "The balancing act: Immunology of leishmaniosis." Research in Veterinary Science 130 (June 2020): 19–25. http://dx.doi.org/10.1016/j.rvsc.2020.02.004.

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Davidson, Robert N., and Pamela Konecny. "Immunology and treatment of the leishmaniases." Current Opinion in Infectious Diseases 8, no. 5 (1995): 336–41. http://dx.doi.org/10.1097/00001432-199510000-00004.

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Tabouret, C., A. Monier, O. Souchaud-Debouverie, F. Roy-Peaud, and P. Roblot. "Leishmaniose viscérale associée à un PTI (purpura thrombopénique immunologique) réfractaire." La Revue de Médecine Interne 36 (December 2015): A124—A125. http://dx.doi.org/10.1016/j.revmed.2015.10.062.

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Vida, Blake, Angela Toepp, Robert G. Schaut, et al. "Immunologic progression of canine leishmaniosis following vertical transmission in United States dogs." Veterinary Immunology and Immunopathology 169 (January 2016): 34–38. http://dx.doi.org/10.1016/j.vetimm.2015.11.008.

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Grimaldi, G., and R. B. Tesh. "Leishmaniases of the New World: current concepts and implications for future research." Clinical Microbiology Reviews 6, no. 3 (1993): 230–50. http://dx.doi.org/10.1128/cmr.6.3.230.

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Recent epidemiologic studies indicate that leishmaniasis in the Americas is far more abundant and of greater public health importance than was previously recognized. The disease in the New World is caused by a number of different parasite species that are capable of producing a wide variety of clinical manifestations. The outcome of leishmanial infection in humans is largely dependent on the immune responsiveness of the host and the virulence of the infecting parasite strain. This article reviews current concepts of the clinical forms, immunology, pathology, laboratory diagnosis, and treatment
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Kubar, Joanna, Pierre Marty, Alain Lelièvre, et al. "Visceral leishmaniosis in HIV-positive patients." AIDS 12, no. 16 (1998): 2147–53. http://dx.doi.org/10.1097/00002030-199816000-00009.

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Bogdan, Christian, Norbert Donhauser, Reinhard Döring, Martin Röllinghoff, Andreas Diefenbach, and Michael G. Rittig. "Fibroblasts as Host Cells in Latent Leishmaniosis." Journal of Experimental Medicine 191, no. 12 (2000): 2121–30. http://dx.doi.org/10.1084/jem.191.12.2121.

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Intracellular parasites are known to persist lifelong in mammalian hosts after the clinical cure of the disease, but the mechanisms of persistence are poorly understood. Here, we show by confocal laser microscopy that in the draining lymph nodes of mice that had healed a cutaneous infection with Leishmania major, 40% of the persisting parasites were associated with fibroblasts forming the reticular meshwork of the lymph nodes. In vitro, both promastigotes and amastigotes of L. major infected primary skin or lymph node fibroblasts. Compared with macrophages, cytokine-activated fibroblasts had a
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Cardoso, Luís, Henk Schallig, Maria Flaminia Persichetti, and Maria Grazia Pennisi. "New Epidemiological Aspects of Animal Leishmaniosis in Europe: The Role of Vertebrate Hosts Other Than Dogs." Pathogens 10, no. 3 (2021): 307. http://dx.doi.org/10.3390/pathogens10030307.

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Infection with Leishmania parasites can lead to severe disease in humans and dogs, which act as a reservoir in zoonotic transmission. An increasing number of reports suggest that leishmaniosis is not restricted to dogs, but also affects many other mammalian and avian species. Consequently, this expands the potential reservoir and is of great public and veterinary health concern. The present study reviews, based on a comprehensive search of scientific literature published from 1 January 2001 to 31 December 2020, the currently available information on animal leishmaniosis in vertebrates in Europ
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Cabral, M., J. E. O'Grady, S. Gomes, J. C. Sousa, H. Thompson, and J. Alexander. "The immunology of canine leishmaniosis: strong evidence for a developing disease spectrum from asymptomatic dogs." Veterinary Parasitology 76, no. 3 (1998): 173–80. http://dx.doi.org/10.1016/s0304-4017(97)00208-2.

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PAPADOGIANNAKIS (E. Ι. ΠΑΠΑΔΟΓΙΑΝΝΑΚΗΣ), E. I., A. F. KOUTINAS (Α.Φ. ΚΟΥΤΙΝΑΣ), and C. KOUTINAS (X.Κ. ΚΟΥΤΙΝΑΣ). "Contemporary aspects on the immunopathogenesis of skin lesions in canine leishmaniosis (Leishmania infantum)." Journal of the Hellenic Veterinary Medical Society 52, no. 4 (2018): 249. http://dx.doi.org/10.12681/jhvms.15453.

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Dog's immunologic reaction to Leishmania infantum inoculation may determine not only the diversity of the observed skin lesions but also the susceptibility or resistance of the dog to develop the disease.The expression of costimulatory molecules, such as B7, by infected macrophages along with the action of cytokines IL-12 and IFN-γ, results in Thl CD4+ cell activation and their infiltration of the dermis. The latter, in turn, activate macrophages to kill the parasite. Failure of the infected macrophages to express these molecules, results in dermis infiltration with Th2 CD4+ cells and macropha
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Dissertations / Theses on the topic "Leishmaniose – Immunologie"

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Bosque, Florence. "Résistance et sensibilité à Leishmania panamensis dans une population humaine : est-il possible de définir des paramètres immunologiques prédictifs ?" Paris 12, 1997. http://www.theses.fr/1997PA120050.

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Le suivi, depuis plus de quinze ans, d'une population humaine exposee a leishmania (viannia) panamensis, a permis de distinguer des individus resistants et des individus sensibles a cette espece de leishmanie. Il a ete possible de beneficier de la participation d'individus de ces deux groupes pour comparer : (1) la permissivite de leurs phagocytes mononuclees exposes ou non a de l'ifn- exogene, a l'entree de promastigotes ou d'amastigotes et a leur devenir intracellulaire, (2) la production de cytokines activatrices (ifn-, tnf-) ou de-activatrices (il-10) des phagocytes mononuclees, par les le
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BRISSE, PICAN FLORENCE. "Leishmaniose viscerale infantile : aspects immunologiques et therapeutiques ; a propos de six cas." Toulouse 3, 1992. http://www.theses.fr/1992TOU31542.

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Forget, Geneviève. "Étude des mécanismes de régulation négative utilisés par Leishmania pour contrer la réponse immunitaire innée." Thesis, Université Laval, 2004. http://www.theses.ulaval.ca/2004/21419/21419.pdf.

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Leishmania est un parasite intracellulaire reconnu pour sa capacité à inhiber sa cellule hôte, le macrophage, et ainsi favoriser sa survie. Il parvient principalement à altérer des fonctions impliquées dans l’action microbicide du phagocyte (dont le monoxyde d’azote (NO)) ou dans la réponse immunitaire. On a associé ce phénomène à l’altération de plusieurs voies de signalisation de la cellule telles celles dépendantes du Ca2+, de la PKC, de JAK2/STAT1α et de ERK1/2. Il a précédemment été démontré que le parasite pouvait, en outre, induire l’activité des phosphotyrosines phosphatases (PTP) et p
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Olekhnovitch, Romain. "The antimicrobial activity of nitric oxide at the site of Leishmania infection." Sorbonne Paris Cité, 2015. http://www.theses.fr/2015USPCC152.

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La production d'oxyde nitrique (NO) par l'enzyme iNOS (inducible NO synthase) est impliquée dans le contrôle de nombreuses infections causées par des pathogènes intracellulaires. Cependant, la nature des signaux nécessaires à l'induction d'iNOS in vivo et les mécanismes responsables de son activité antimicrobienne restent à définir. En particulier, plusieurs études suggèrent que le NO exerce son activité de manière intrinsèque : l'induction d'iNOS par les cellules infectées leur permettrait donc de contrôler individuellement leur charge microbienne. Alternativement, la capacité du NO à diffuse
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Mille, Mireille. "Application de la methode elisa au suivi sero-immunologique d'une population canine vaccinee contre la leishmaniose." Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20905.

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Mathias, Regiane. ""Imunoglobulina na patogenia da leishmaniose visceral em hamsteres"." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-21082006-111603/.

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A patogênese das lesões teciduais na leishmaniose visceral (LV) foi pesquisada em hamsteres infectados com amastigotas de Leishmania (Leishmania.) chagasi. Foi observada a internalização de IgG de hamsteres com LV por células endoteliais da veia umbilical humana in vitro e no fígado e rim, sob microscopia eletrônica de transmissão aos 30 e 60 dias de infecção. Também foi observado o aumento na permeabilidade vascular aos 60 dias de infecção e a IgG purificada de hamsteres com LV induziu aumento na permeabilidade em hamsteres normais. Os resultados sugerem a internalização de IgG por células en
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Bregano, Livia Castanhas. "Genes da resposta imune inata e adaptativa diferencialmente expressos em cérebros de cães com Leishmaniose Visceral /." Araçatuba, 2018. http://hdl.handle.net/11449/155859.

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Orientador: Gisele Fabrino Machado<br>Banca: Flávia Lombardi Lopes<br>Banca: Valéria Marçal Felix de Lima<br>Banca: Sandra Helena Penha de Oliveira<br>Resumo: A leishmaniose visceral canina (LVC) é uma doença crônica, invariavelmente progressiva, de alta variabilidade clínica, incluindo desordens neurológicas. Para investigar as alterações neurológicas desencadeadas pela LVC, a expressão de genes envolvidos na resposta imune inata e adaptativa em cérebros de cães naturalmente infectados para Leishmania infantum foi realizada. Cães machos/fêmeas, 1 a 5 anos de idade, sem raça definida, com prév
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FERRUA, AGNES. "A propos du diagnostic immunologique de la leishmaniose viscerale : evaluation d'un test elisa pour le titrage des immunoglobulines de type g anti-leishmania." Toulouse 3, 1992. http://www.theses.fr/1992TOU31708.

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Soutter, Francesca. "Canine leishmaniosis : immunogenetics of response to infection and vaccination." Thesis, Royal Veterinary College (University of London), 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.701667.

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Luz, Kleber Giovanni. "Avaliação das alterações imunohistológicas da mucosa do intestino delgado em pacientes portadores da leishmaniose visceral." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/5/5134/tde-09102014-090745/.

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INTRODUÇÃO: A leishmaniose visceral é uma doença que acomete cerca de 500 mil pessoas por ano no mundo e se caracteriza principalmente por um quadro de febre, hepatoesplenomegalia e pancitopenia. Há uma imunossupressão específica frente a Leishmania chagasi. Classicamente esta resposta é modulada pelas células dendríticas, que são as primeiras células que entram em contato com o parasita. Estas células, a partir de vários determinantes, elaboram uma resposta do tipo Th1, com a produção de citocinas capazes de ativar os macrófagos a eliminar o parasita ou uma resposta do tipo Th2, que se caract
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Book chapters on the topic "Leishmaniose – Immunologie"

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Alexander, J., and D. G. Russell. "Parasite Antigens, Their Role in Protection, Diagnosis and Escape: The Leishmaniases." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-662-09197-5_4.

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