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Dissertations / Theses on the topic 'Leprosy'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Dahlberg, Samuel. "Leprosy: life(expectancy)." Thesis, Uppsala universitet, Arkeologi, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-447984.

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Denna kandidatuppsats (C-uppsats) kommer att undersöka sjukdomen lepra utifrån ett socialt perspektiv med syftet att undersöka om livslängden hos infekterade människor (i Europa) påverkades på något sätt utifrån det samtida samhällets regerande normer och perspektiv. Rådande Covid-19 pandemin har omöjliggjort egna osteologiska undersökningar, vilket är varför denna studie kommer grundas i andra arkeologers redan publicerade rapporter. Källmaterial för den sociala biten grundar sig i relevanta textuella skrifter, vilket inkluderar både modernt och historiskt material samt religiösa teman för br

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2

Rezende, Daniela Ventin Prates. "Expression of regulatory t cells in polar leprosy and leprosy reactions." Universidade Federal do CearÃ, 2013. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=10882.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>Leprosy is a chronic infectious disease caused by Mycobacterium leprae and presents a wide range of clinical manifestations, depending on the host immune response. At the tuberculoid pole, patients have an effective Th1 cellular immune response against bacillus, with well-demarcated granulomas, which limits the disease, while the lepromatous pole is characterized by the absence of specific cellular immunity against Mycobacterium leprae, with a Th2 immune response, uncontrolled proliferation of leprosy bacilli and a spread disease.

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3

Jabez, John. "The History of Leprosy." The University of Arizona, 2018. http://hdl.handle.net/10150/626584.

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4

Alter, Andrea. "Genetic susceptibility to leprosy." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=94959.

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Leprosy (Hansen's disease) is a human infectious disease that can be effectively treated with 6-12 month administration of multi-drug therapy. In 2008, approximately 250,000 new cases were reported to the World Health Organization. The etiological agent, Mycobacterium leprae, was identified by G.H.A. Hansen in the nineteenth century. Subsequent to exposure, epidemiological studies maintain the importance of host genetics in leprosy susceptibility. A previous model-free genome-wide linkage scan in multi-case families from Vietnam detected linkage between chromosome region 6p21 (lod = 2.62)

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5

Akeli, Safua. "Leprosy in Samoa 1890 to 1922 : race, colonial politics and disempowerment : a thesis submitted in fulfilment of the requirements for the degree of Master of Arts in History at the University of Canterbury /." Thesis, University of Canterbury. History, 2007. http://hdl.handle.net/10092/999.

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This thesis investigates the colonial organisation of leprosy care in Samoa from 1890 to 1922. It begins with the examination of the nineteenth century “Three Power” governments of Germany, United States of America and Great Britain over Samoa, and moves on to a study of German rule beginning in 1900 and New Zealand administration from 1914. It analyses colonial politics alongside the medical changes and exchanges of ideas about race, health and disease which dominated the direction of leprosy care in Samoa. During these thirty two years of European influence and control over Samoan affairs, t

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6

Win, Le Le. "Changes in self-care behaviour : effect of self-care teaching on prevention of disability in leprosy patients, Myanmar /." [St. Lucia, Qld.], 2005. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe19087.pdf.

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7

Schön, Thomas. "Nitric oxide in tuberculosis and leprosy /." Linköping, 2002. http://www.bibl.liu.se/liupubl/disp/disp2002/med749s.pdf.

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8

Meisner, Sarah. "The genetics of susceptibility to leprosy." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298995.

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9

Bwire, Robert. "Interactions of HIV with leprosy and tuberculosis." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2006. http://dare.uva.nl/document/28528.

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10

McMenamin, Dorothy. "Leprosy and Stigma in the South Pacific: Camaraderie in Isolation." Thesis, University of Canterbury. School of Humanities, 2009. http://hdl.handle.net/10092/2913.

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The oral histories utilized by this research reveal the experiences of those who suffered leprosy in five South Pacific nations, Fiji, New Caledonia, Samoa, Tonga and Vanuatu. This thesis explores how leprosy and its stigma impacted on the lives of these people, some of whom suffered decades of isolation at various leprosaria including the case of one New Caledonian resident for nearly seventy years. The testimonies of their experiences of diagnosis, removal into isolation, medical treatment and eventual discharge back to their homes implicitly contain descriptions of attitudes of stigma in th

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11

Bergman, Love, and Asabea Britton. "Nurse's experiences of leprosy related stigma in Ghana." Thesis, Ersta Sköndal högskola, Institutionen för vårdvetenskap, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:esh:diva-3941.

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Background: Leprosy has long been associated with stigma and the disease causes a lot of suffering to those affected, not only physically but also emotionally and psychologically due to the effects of stigma. Aim: To describe the nurse’s experiences of leprosy related stigma in the Central Region of Ghana. Methods: A qualitative interview study with semi-structured interviews. Seven individual interviews were conducted four with nurses working at a hospital, specializing in leprosy care, at in the Central Region of Ghana. The data was analyzed using a content analysis based on Graneheim and Lu

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12

Kirkaldy, Alice Amanda. "The role of chemokines in leprosy skin lesions." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268729.

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13

Besra, Gurdyal Singh. "Studies on the lipids of the leprosy bacillus." Thesis, University of Newcastle Upon Tyne, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303125.

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14

Pearson, M. A. "Leprosy in West Nepal : Social and spatial perspectives." Thesis, University of Liverpool, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.378448.

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15

Smith, W. C. S. "Evaluation of a leprosy control programme in India." Thesis, University of Aberdeen, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.372441.

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16

Nakachi, Shogo Wichai Supanaranond. "Outcome of treatment in leprosy reactions /cShogo Nakachi." Abstract, 2006. http://mulinet3.li.mahidol.ac.th/thesis/2549/cd388/4838789.pdf.

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Thematic Paper (M.C.T.M. (Clinical Tropical Medicine))--Mahidol University, 2006.<br>LICL has E-Thesis 0012 ; please contact computer services. LIRV has E-Thesis 0012 ; please contact circulation services.

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17

Bouka, Aimée-Angélique. "Functional studies of PARK2/PACRG leprosy susceptibility factor." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119759.

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Leprosy is a chronic human infectious disease that is caused by Mycobacterium leprae, a slow growing intracellular parasite mostly of macrophages and Schwann cells. In 2010, there were an estimated 228,474 new cases worldwide. Research conducted for decades has strongly suggested that genetic factors participate in host susceptibility to leprosy. Employing a positional cloning approach, the Schurr group had identified genetic variants in the shared PARK2/PACRG promoter region as major leprosy susceptibility factors. Specifically, it was possible to identify two PARK2 promoter allelic combinati

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18

Vadher, Atul. "Patient treatment compliance in leprosy : a social psychological perspective." Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303622.

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19

Gollnick, Emily. "Leprosy in the Dakhleh Oasis (Egypt) During Roman Rule." Honors in the Major Thesis, University of Central Florida, 2004. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/430.

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This item is only available in print in the UCF Libraries. If this is your Honors Thesis, you can help us make it available online for use by researchers around the world by following the instructions on the distribution consent form at http://library.ucf<br>Bachelors<br>Arts and Sciences<br>Anthropology

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20

Bührer-Sékula, Samira. "A simple dipstick assay for leprosy development, evaluation and application /." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2000. http://dare.uva.nl/document/55198.

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21

Moet, Fake Johannes. "Contacts of leprosy patients: occurance and prevention of the disease." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2007. http://hdl.handle.net/1765/10513.

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22

Mira, Marcelo Távora. "A study of host genetic risk factors for leprosy susceptibility /." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84296.

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Leprosy, a chronic infectious disease caused by Mycobacterium leprae, is the leading cause of non-traumatic neuropathies in the world. Although a genetic component for leprosy susceptibility has been demonstrated by several studies, the exact nature and extent of this component is still unknown. Here, we applied linkage and association analysis in a combined candidate region and genome-wide approach to further investigate the nature of host genetic factors controlling leprosy susceptibility. First, we used 20 Vietnamese multiplex leprosy families to perform linkage analysis on selected

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23

Walker, Stephen L. "The measurement, treatment and immunopathology of leprosy type 1 reactions." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.536876.

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24

Clouatre, Elsa. "«In-vitro» functional studies of the «LTA+80A» leprosy risk factor." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=66819.

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Introduction Leprosy is a disease caused by Mycobacterium leprae that affects an estimated 300,000 new cases each year. The LTA+80 A promoter allele, a strong leprosy risk factor (Alcais et al. 2007), has been shown to facilitate binding of the ABF1 transcriptional repressor in human B-cells (Knight et al. 2004). Direct studies on the impact of LTA+80 genotypes on LTA expression levels following exposure of human cells to M. leprae are missing. Results Comparative analysis of LTA expression in M. leprae stimulated and un-stimulated human blood samples revealed that LTA expres

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25

Jones, Janet. "Issues in leprosy and social isolation : a case study from Nepal." Thesis, University of Derby, 2006. http://hdl.handle.net/10545/297119.

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26

Brahmbhatt, Shweta. "Development of synthetic peptide reagents as a diagnostic tool for leprosy." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251991.

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27

Rafi, Abdolnasser. "Molecular and immunological studies on #fully treated' long term leprosy patients." Thesis, University College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283434.

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28

Roy, Suchismita. "The association between HLA-DR antigens, TNF alpha polymorphisms and leprosy." Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361692.

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29

Obregón, Torres Diana. "Struggling against leprosy: physicians, medicine, and society in Colombia, 1880-1940." Diss., Virginia Tech, 1996. http://hdl.handle.net/10919/39087.

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30

Haroun, Omer Mohammed Osman Hamid. "Neuropathic pain in leprosy : deep profiling and stratification of patient groups." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2015. http://researchonline.lshtm.ac.uk/2030956/.

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Leprosy is a chronic granulomatous infectious disease, affecting the skin and nerves. Neuropathic pain (NP), which is defined as pain caused by a lesion or disease of the somatosensory nervous system, is now being recognized as an important complication of leprosy. It occurs in 10-20% of patients as a result of persisting nerve damage. Patient with NP is associated with significant suffering, morbidity and limitation of quality of life. Thus, the accurate identification of NP in patients with pain is required. The clinical aspects of NP in leprosy patients in India were investigated using high

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31

McKnight, C. Jason. "Clinical testing and prognostic markers for the development of leprosy neuropathy." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.536801.

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32

Messali, Jean-Pierre. "La "lèpre" dans les écrits bibliques et rabbiniques : aspects historiques, textuels et rituels." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCA037/document.

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Pendant plus de deux mille ans, les historiens ont colporté une légende : les Juifs ont été expulsés d'Egypte car ils étaient porteurs de la lèpre. L'étude de la maladie de Hansen (nom actuel de la lèpre) et les différentes recherches, historiques (sur les textes des historiens de l'Antiquité) et archéologiques permettent de contester certains écrits et de prouver que cette légende, qui s'est perpétuée jusqu'au milieu du XXème siècle, était fausse.Cependant, la Bible hébraïque consacre deux chapitres du Lévitique à une affection qui peut toucher les hommes, les vêtements et les maisons, et le

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33

Perez, Manuel Hernandez. "IS1110 : a highly mobile insertion sequence from Mycobacterium avium." Thesis, University of Surrey, 1995. http://epubs.surrey.ac.uk/842785/.

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A new mobile insertion sequence designated IS1110 was detected in the strain LR541 of Mycobacterium avium due to an observed increase of the size of the plasmid pLR20. Genomic libraries of M. avium containing the original plasmid pLR20 and the modified plasmid pLR20' were constructed using the phage gammagt10 as the vector. In order to characterize the insertion sequence as well as the region of inserted DNA, the sequence of the relevant clones was determined. IS1110 is a 1457 bp element lacking terminal inverted repeats and it is related to other insertion sequences such as IS900 (M.paratuber

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34

Weir, Rosemary Edith. "Field studies of the human cell-mediated immune response to mycobacterium leprae using a whole blood assay." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264192.

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35

Adeleye, Tolulope Abiodun. "A molecular analysis of the immunological response to mycobacterial antigens." Thesis, University College London (University of London), 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304066.

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36

Heijnders, Maria Louisa. "Understanding adherence in leprosy : experiencing and making sense of leprosy and its treatment in its social context : a qualitative study conducted in the eastern Terai region of Nepal." Thesis, London South Bank University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618671.

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37

Nuorala, Emilia. "Molecular palaeopathology : ancient DNA analyses of the bacterial diseases tuberculosis and leprosy /." Stockholm : Archaeological Research Laboratory [Arkeologiska forskningslaboratoriet], Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-231.

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38

Jamieson, S. E. "The genetics of susceptibility to tuberculosis and leprosy in a Brazilian population." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.605053.

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The region of conserved synteny on mouse chromosome 11/human 17q11.2-q22 has been identified as carrying susceptibility genes for intramacrophage pathogens. This region contains numerous candidate genes including, <i>NOS2A</i> encoding inducible nitric oxide synthase, the β-chemokine gene cluster (including <i>CLL2/MCP-1, CCL3/MIP-1</i><i>α, CCL4/MIP-1</i><i>β, CCL5/RANTES), CCR7</i> encoding the receptor for <i>CCL19/CCL21</i>, and genes for signal transducers and activators of transcription <i>STAT3</i> and <i>STAT5A/5B</i>. To determine the role of this region in susceptibility to mycobacte

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39

Brightmer, Mary Irene. "The spatial pattern of leprosy in the Cross River region of Nigeria." Thesis, University of Liverpool, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358948.

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40

Andersson, Anna Kristina. "The effect of prednisolone on cytokine expression in leprosy type 1 reactions." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424513.

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41

Brooks, Lucy Anna. "An investigation into the molecular genetics of cell wall biosynthesis in Mycobacterium leprae." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362368.

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42

Mahmud, Roziahanim. "The chemical and biochemical basis of dapsone toxicity." Thesis, University of Liverpool, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307617.

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43

Ferreira, Emerson Ramalho. "A revacinaÃÃo com a bcg modula a produÃÃo de citocinas frente a antÃgenos do Mycobacterium leprae, em contatos menores de 15 anos de pacientes com hansenÃase." Universidade Federal do CearÃ, 2010. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7317.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>Estudos em diferentes populaÃÃes tÃm mostrado que a vacinaÃÃo com a BCG concede proteÃÃo parcial contra a hansenÃase. Entretanto, a necessidade da revacinaÃÃo e seu impacto na resposta imune contra antÃgenos do Mycobacterium leprae Ã pouco compreendida, principalmente nas crianÃas que sÃo contatos destes pacientes com hansenÃase, e constituem uma populaÃÃo de risco para o adoecimento. Neste estudo, investigamos o papel da revacinaÃÃo com a BCG na modulaÃÃo da resposta imune em contatos menores de quinze anos de pacientes com hansen

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44

Carloni, Maria Emília Oliveira Gomes. "Aspectos sociodemográficos e epidemiológicos dos casos de hanseníase em uma área endêmica : conhecimentos e experiências de cirurgiões-dentistas /." Araçatuba, 2015. http://hdl.handle.net/11449/134290.

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Orientador: Ronald Jefferson Martins<br>Coorientadora: Suzely Adas Saliba Moimaz<br>Banca: Tânia Adas Saliba Rovida<br>Banca: Roosevelt da Silva Bastos<br>Resumo: A hanseníase é uma doença infecciosa crônica causada pelo Mycobacterium leprae, que acomete preferencialmente pele e nervos periféricos, com um grande potencial para desenvolver incapacidades físicas. A redução da transmissibilidade e do número de doentes com lesões incapacitantes depende do incremento do diagnóstico precoce da doença. Os objetivos do presente trabalho foram conhecer as principais características epidemiológicas de i

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45

Caulfield, Tanya. ""It is like you have leprosy" : representations of single women in Delhi, India /." [St. Lucia, Qld.], 2005. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe19329.pdf.

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46

Marlowe, Sharon Nalini Singh. "Azathioprine and cyclosporin A as second line treatments for severe leprosy type reactions." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424945.

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47

Black, G. F. "An immunogenetic study of susceptibility to leprosy and tuberculosis in a Brazilian population." Thesis, University of Cambridge, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596677.

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Human 5q23-32 contains a cluster of genes (IL3/4/5/9) for interleukins commonly associated with disease exacerbatory T helper 2 immune responses in mycobacterial infections. Human 17q11.2-q12 contains the gene (NOS2A) encoding macrophage-expressed inducible nitric oxide synthase (iNOS), which generates toxic nitric oxide for antimicrobial activity, and an array of genes (SCYA1/2/5) encoding small inducible chemokines which act as monocyte chemoattractants and are involved in inflammatory responses. To study the role of these two regions in human disease susceptibility, DNA from a series of 40

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48

Fuller, Gary Stephen. "The Virgin's Kiss: Gender, Leprosy, and Romance in the Life of St. Frideswide." BYU ScholarsArchive, 2012. https://scholarsarchive.byu.edu/etd/3234.

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The longer thirteenth-century Middle English verse life of Saint Frideswide found in the collection of saints' lives known as the South English Legendary (SEL) narrates an event unique to medieval hagiography. In the poem, a leper asks the virgin saint to kiss him with her "sweet mouth," which she does in spite of her feelings of considerable shame, and the leper is healed. The erotic nature of the leper's request, Frideswide's reluctance to grant it, and her shame throughout the incident represent a significant departure from the twelfth-century Latin texts on which the SEL version of the sai

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49

Papadopoulou, S., and Jo Buckberry. "The relationship between Vitamin D deficiency and leprosy in two English medieval populations." University of Sheffield, 2019. http://hdl.handle.net/10454/17508.

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Yes<br>In palaeopathology, a well-established approach to malnutrition and ill-health is the study of metabolic conditions. Leprosy is a mycobacterial disease that is manifested on the bones, and is commonly studied in archaeological contexts. Vitamin D is essential for maintaining a normal immune system, and thus a metabolic insufficiency could have a major effect in the resistance of an individual to invading pathogens. It has been indicated by clinical studies that there is an increase in the risk of contracting tuberculosis for individuals with Vitamin D deficiency, and like TB, lepr

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50

CARVALHO, Rosely de Brito Pereira. "Aspectos Psicossociais de pacientes portadores de reações hansênicas no Município de Buriticupu, Estado do Maranhão." Universidade Federal do Maranhão, 2014. https://tedebc.ufma.br/jspui/handle/tede/tede/1976.

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Submitted by Daniella Santos (daniella.santos@ufma.br) on 2017-10-31T12:55:33Z No. of bitstreams: 1 RoselyCarvalho.pdf: 412156 bytes, checksum: ab3deaf24c1695dc2de6c64feecb3f66 (MD5)<br>Made available in DSpace on 2017-10-31T12:55:33Z (GMT). No. of bitstreams: 1 RoselyCarvalho.pdf: 412156 bytes, checksum: ab3deaf24c1695dc2de6c64feecb3f66 (MD5) Previous issue date: 2014-08-22<br>This paper studied the psychosocial effects in patients who developed leprosy reaction in Buriticupu’s municipality, State of Maranhão, seeking to ascertain how these aspects affect social interrelationships, the

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