Log in

Relevant bibliographies by topics / Lethal irradiation / Journal articles

To see the other types of publications on this topic, follow the link: Lethal irradiation.

Journal articles on the topic 'Lethal irradiation'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Lethal irradiation.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Huang, Zhentai, Michael Epperly, Simon C. Watkins, Joel S. Greenberger, Valerian E. Kagan, and Hülya Bayır. "Necrostatin-1 rescues mice from lethal irradiation." Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1862, no. 4 (2016): 850–56. http://dx.doi.org/10.1016/j.bbadis.2016.01.014.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Talmadge, JE, H. Tribble, R. Pennington, et al. "Protective, restorative, and therapeutic properties of recombinant colony-stimulating factors." Blood 73, no. 8 (1989): 2093–103. http://dx.doi.org/10.1182/blood.v73.8.2093.2093.

Full text

Abstract:

Abstract Pretreatment of mice with recombinant murine (rM) colony-stimulating factor-granulocyte-macrophage (CSF-gm) or recombinant human (rH) CSF-g provides partial protection from the lethal effects of ionizing radiation or the alkylating agent cyclophosphamide (CTX). In addition, these agents can significantly prolong survival if administered following lethal doses of irradiation or CTX. To induce protective activity, cytokines were injected 20 hours before lethal irradiation or CTX administration. To accelerate recovery from lethal irradiation, the cytokines must be administered shortly fo

APA, Harvard, Vancouver, ISO, and other styles

3

Talmadge, JE, H. Tribble, R. Pennington, et al. "Protective, restorative, and therapeutic properties of recombinant colony-stimulating factors." Blood 73, no. 8 (1989): 2093–103. http://dx.doi.org/10.1182/blood.v73.8.2093.bloodjournal7382093.

Full text

Abstract:

Pretreatment of mice with recombinant murine (rM) colony-stimulating factor-granulocyte-macrophage (CSF-gm) or recombinant human (rH) CSF-g provides partial protection from the lethal effects of ionizing radiation or the alkylating agent cyclophosphamide (CTX). In addition, these agents can significantly prolong survival if administered following lethal doses of irradiation or CTX. To induce protective activity, cytokines were injected 20 hours before lethal irradiation or CTX administration. To accelerate recovery from lethal irradiation, the cytokines must be administered shortly following i

APA, Harvard, Vancouver, ISO, and other styles

4

Chen, Benny J., Divino Deoliveira, and Nelson Chao. "Insulin-Like Growth Factor 1 Protects against Lethal Irradiation." Blood 112, no. 11 (2008): 3488. http://dx.doi.org/10.1182/blood.v112.11.3488.3488.

Full text

Abstract:

Abstract Ionizing irradiation can cause bone marrow failure leading to death. Effective therapeutic agents capable of promoting or accelerating the recovery of the hematopoietic and/or immune compartment following radiation injury are limited. We and others have previously demonstrated that recombinant human growth hormone promotes hematopoietic and immune recovery following stem cell transplantation and irradiation. Published data suggest that growth hormone elicits its pro-hematopoietic effects via action of insulin-like growth factor 1 (IGF1). Since IGF1 has recently been approved by the Fe

APA, Harvard, Vancouver, ISO, and other styles

5

SALIN, C. "Protection of mouse jejunum against lethal irradiation by." Phytomedicine 8, no. 6 (2001): 413–22. http://dx.doi.org/10.1078/s0944-7113(04)70059-8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Tiberghien, P., V. Laithier, M. Mabed, et al. "Interleukin-1 administration before lethal irradiation and allogeneic bone marrow transplantation: early transient increase of peripheral granulocytes and successful engraftment with accelerated leukocyte, erythrocyte, and platelet recovery." Blood 81, no. 7 (1993): 1933–39. http://dx.doi.org/10.1182/blood.v81.7.1933.1933.

Full text

Abstract:

Abstract Administration of interleukin-1 beta (IL-1 beta) before a lethal irradiation with or without allogeneic bone marrow transplantation (BMT) protects greater than 90% of the irradiated mice. To approach the mechanisms responsible for the radioprotective effect of IL-1, we examined the effects of IL-1 pretreatment on engraftment and kinetics of peripheral blood, spleen, and marrow cell reconstitution after irradiation and BMT. Although the BMT was not necessary for the survival of the IL-1-pretreated lethally irradiated mice, allogeneic marrow did engraft in these mice as evaluated in the

APA, Harvard, Vancouver, ISO, and other styles

7

Tiberghien, P., V. Laithier, M. Mabed, et al. "Interleukin-1 administration before lethal irradiation and allogeneic bone marrow transplantation: early transient increase of peripheral granulocytes and successful engraftment with accelerated leukocyte, erythrocyte, and platelet recovery." Blood 81, no. 7 (1993): 1933–39. http://dx.doi.org/10.1182/blood.v81.7.1933.bloodjournal8171933.

Full text

Abstract:

Administration of interleukin-1 beta (IL-1 beta) before a lethal irradiation with or without allogeneic bone marrow transplantation (BMT) protects greater than 90% of the irradiated mice. To approach the mechanisms responsible for the radioprotective effect of IL-1, we examined the effects of IL-1 pretreatment on engraftment and kinetics of peripheral blood, spleen, and marrow cell reconstitution after irradiation and BMT. Although the BMT was not necessary for the survival of the IL-1-pretreated lethally irradiated mice, allogeneic marrow did engraft in these mice as evaluated in the spleen a

APA, Harvard, Vancouver, ISO, and other styles

8

Montfort, Megan J., Christopher R. Olivares, Jean M. Mulcahy, and William H. Fleming. "Adult blood vessels restore host hematopoiesis following lethal irradiation." Experimental Hematology 30, no. 8 (2002): 950–56. http://dx.doi.org/10.1016/s0301-472x(02)00813-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Lange, Claudia, Bärbel Brunswig-Spickenheier, Heike Cappallo-Obermann, et al. "Radiation Rescue: Mesenchymal Stromal Cells Protect from Lethal Irradiation." PLoS ONE 6, no. 1 (2011): e14486. http://dx.doi.org/10.1371/journal.pone.0014486.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Goel, H. C., Madhu Bala, J. Prasad, S. Singh, P. K. Agrawala, and R. C. Swahney. "Radioprotection byRhodiola imbricatain Mice Against Whole-Body Lethal Irradiation." Journal of Medicinal Food 9, no. 2 (2006): 154–60. http://dx.doi.org/10.1089/jmf.2006.9.154.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Neta, R., D. Williams, F. Selzer, and J. Abrams. "Inhibition of c-kit ligand/steel factor by antibodies reduces survival of lethally irradiated mice." Blood 81, no. 2 (1993): 324–27. http://dx.doi.org/10.1182/blood.v81.2.324.324.

Full text

Abstract:

Abstract Survival after irradiation with LD100/30 (radiation dose lethal to 100% of mice in 30 days) is based on recovery of impaired hematopoietic function. Our previous studies using antibodies to interleukin-1 receptor (IL–1R), tumor necrosis factor (TNF), and IL–6 demonstrated that endogenous production of these three cytokines is required for untreated mice as well as mice protected with lipopolysaccharide (LPS), IL–1, or TNF to survive lethal irradiation. In this report we show that anti-c-kit ligand/steel factor (SIF) antibody similarly abrogates LPS- and IL-1-induced radioprotection. F

APA, Harvard, Vancouver, ISO, and other styles

12

Neta, R., D. Williams, F. Selzer, and J. Abrams. "Inhibition of c-kit ligand/steel factor by antibodies reduces survival of lethally irradiated mice." Blood 81, no. 2 (1993): 324–27. http://dx.doi.org/10.1182/blood.v81.2.324.bloodjournal812324.

Full text

Abstract:

Survival after irradiation with LD100/30 (radiation dose lethal to 100% of mice in 30 days) is based on recovery of impaired hematopoietic function. Our previous studies using antibodies to interleukin-1 receptor (IL–1R), tumor necrosis factor (TNF), and IL–6 demonstrated that endogenous production of these three cytokines is required for untreated mice as well as mice protected with lipopolysaccharide (LPS), IL–1, or TNF to survive lethal irradiation. In this report we show that anti-c-kit ligand/steel factor (SIF) antibody similarly abrogates LPS- and IL-1-induced radioprotection. Furthermor

APA, Harvard, Vancouver, ISO, and other styles

13

MELO, Alan Lane de, and Munir CHAMONE. "Schistosoma mansoni: inflammatory foci around larvae in the peritoneal cavity of naive mice is radiosensitive." Revista do Instituto de Medicina Tropical de São Paulo 43, no. 2 (2001): 63–65. http://dx.doi.org/10.1590/s0036-46652001000200002.

Full text

Abstract:

Innate attack to Schistosoma mansoni cercariae was evaluated in irradiated mice. It was observed that 70% of the larvae from mice sacrificed one day after whole body irradiation with 400 or 800 rads were surrounded by cluster reactivities, without difference from controls. Differences were apparent on day 5 after irradiation with sub lethal (400 rads) or lethal doses (800 rads) suggesting that innate defence to infection take at least 5 days to be affected by low dose whole-body radiation.

APA, Harvard, Vancouver, ISO, and other styles

14

Saragih, Siti Hartati Yusida. "EFEK IRADIASI SINAR GAMMA PADA TANAMAN KACANG PENUTUP TANAH (Mucuna bracteata L.)." JURNAL AGROPLASMA 8, no. 1 (2021): 6–10. http://dx.doi.org/10.36987/agroplasma.v8i1.2088.

Full text

Abstract:

Legume cover crop (Mucuna bracteata L.) is a creeper which is currently often used to increase soil fertility in plantation areas. This plant is a leguminous plant that can fix nitrogen nutrients in the soil. One of the M.bracteata plant breeding programs to increase diversity is mutation using gamma ray radiation. The research objective was to determine the level of radiosensitivity of legume cover crop using gamma ray irradiation. The research was conducted at PAIR BATAN using a Gamma Chamber 4000A irradiator and in agricultural experiment, Labuhanbatu University. The plant material used was

APA, Harvard, Vancouver, ISO, and other styles

15

Li, Xiao-Miao, Zhongbo Hu, Marda L. Jorgenson, John R. Wingard, and William B. Slayton. "Bone Marrow Sinusoidal Endothelium Undergoes DNA Damage and Repair Following Lethal Irradiation." Blood 110, no. 11 (2007): 4866. http://dx.doi.org/10.1182/blood.v110.11.4866.4866.

Full text

Abstract:

Abstract In the light of the possibility that adult bone marrow cells possess hemangioblast ability, work from our laboratory demonstrates that the bone marrow sinusoids remain predominantly host-derived following bone marrow transplant when ionizing irradiation is used as the conditioning regimen. To determine the effect of lethal irradiation to the host sinusoidal endothelial cells, we performed four apoptosis related assays and two cell proliferation assays on bone marrow sections at various time points during the first two weeks post-irradiation. We found: Phosphorylated H2AX was present i

APA, Harvard, Vancouver, ISO, and other styles

16

Christensen, J. L., S. Smith, D. Gille, et al. "Ex vivo generated myeloid progenitors protect mice from lethal irradiation." Biology of Blood and Marrow Transplantation 11, no. 2 (2005): 56–57. http://dx.doi.org/10.1016/j.bbmt.2004.12.169.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Dong, Mei-Yan, Te-Wen Chang, and Sherwood L. Gorbach. "Effects of feeding lactobacillus GG on lethal irradiation in mice." Diagnostic Microbiology and Infectious Disease 7, no. 1 (1987): 1–7. http://dx.doi.org/10.1016/0732-8893(87)90063-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Mazinani, Sina Atrin, Nour Noaman, Melissa R. Pergande, Stephanie M. Cologna, Jens Coorssen, and Hongbin Yan. "Exposure to microwave irradiation at constant culture temperature slows the growth ofEscherichia coliDE3 cells, leading to modified proteomic profiles." RSC Advances 9, no. 21 (2019): 11810–17. http://dx.doi.org/10.1039/c9ra00617f.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Boiko, R., D. Bilko, I. Russu, and N. Bilko. "COMPARATIVE MATHEMATICAL ANALYSIS OF COLONY-FORMING ABILITYOF THE BONE MARROW OF MICE LETHALLY AND NON-LETHALLY IRRADIATED WITH EQUAL DOSE RATE INTENSITY." Проблеми радіаційної медицини та радіобіології = Problems of Radiation Medicine and Radiobiology 25 (2020): 300–308. http://dx.doi.org/10.33145/2304-8336-2020-25-300-308.

Full text

Abstract:

Objective. To perform comparative analysis of the characteristics of population functioning process of mice bone marrow colony-forming units after their prolonged irradiation in lethal and non-lethal doses with equal dose rate intensity with the aid of mathematical model. Materials and methods. Assigned task is solved by means of mathematical model of alterations in the number of bone marrow colony-forming units after continuous irradiation, described in previous works, with the use of experimental results of K. S. Chertkov works (1972, 1973). Mathematical model is developed basing on the hema

APA, Harvard, Vancouver, ISO, and other styles

20

Martinovic, Vesna, Zarko Ivanovic, Mirjana Mihailovic, Svetlana Ivanovic-Matic, Goran Poznanovic, and Melita Vidakovic. "Lymphocytes’ ‘last stand’ on the nuclear matrix after whole body exposure of rats to low-let ionizing radiation." Archives of Biological Sciences 67, no. 1 (2015): 69–81. http://dx.doi.org/10.2298/abs140124002m.

Full text

Abstract:

We examined the functions of the rat lymphocyte nuclear matrix after a single exposure to total body irradiation with doses ranging from sublethal to lethal. Irradiation induced systemic oxidative stress, detected as increased activities of serum SOD and catalase, lymphocyte DNA damage, detected by the Comet assay, and apoptosis. After irradiation with lower doses, the recruitment of DNA repair centers on the matrix was observed by Western analysis as increased levels of matrix-associated PARP-1, p53 and PCNA. Augmented partitioning of the pro-survival transcription factor NF-?B on the matrix

APA, Harvard, Vancouver, ISO, and other styles

21

Cahyo, Fitro Adi, and Diny Dinarti. "Pengaruh Iradiasi Sinar Gamma terhadap Pertumbuhan Protocorm Like Bodies Anggrek Dendrobium lasianthera (JJ. Smith) secara In Vitro." Jurnal Hortikultura Indonesia 6, no. 3 (2015): 177. http://dx.doi.org/10.29244/jhi.6.3.177-186.

Full text

Abstract:

<p>ABSTRACT</p><p><br />The objective of this research was to determine the effects of gamma irradiation on protocorm like bodies (PLBs) Dendrobium lasianthera and Lethal dose (LD) 30 and 50 of gamma irradiation. The irradiation was conducted at the Center of Technology Application of Isotops and Radiation, Nuclear Energy Agency (PATIR-BATAN) and culture at Tissue Culture Laboratory of IPB from February 2014 to July 2014. The treatments were arranged in a completely randomized design (CRD) with a single factor of gamma irradiation doses, include i,g. 0 Gy, 20 Gy, 40 Gy,

APA, Harvard, Vancouver, ISO, and other styles

22

Yang, Xiaodong, Ilango Balakrishnan, Beverly Torok-Storb, and Manoj M. Pillai. "Marrow Stromal Cell Infusion Rescues Hematopoiesis in Lethally Irradiated Mice despite Rapid Clearance after Infusion." Advances in Hematology 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/142530.

Full text

Abstract:

Marrow stromal cells (MSCs, also termed mesenchymal stem cells) have been proposed as a promising cellular therapy for tissue injury including radiation-induced marrow failure, but evidence for a direct effect is lacking. To assess the effects of MSCs on survival after lethal irradiation, we infused syngeneic MSCs (either as immortalized MSCs clones or primary MSCs) intravenously into wild-type C57/Bl6 mice within 24 hours of lethal total body irradiation (TBI). Mice receiving either of the MSC preparations had significantly improved survival when compared to controls. In vivo imaging, immune

APA, Harvard, Vancouver, ISO, and other styles

23

Imai, T., M. Onozawa, T. Takekawa, and T. Shakudo. "Lethal and Sterile Effects of X-ray Irradiation on Cigarette Beetle, Lasiodermaserricorne (F.) (Coleoptera: Anobiidae)." Beiträge zur Tabakforschung International/Contributions to Tobacco Research 22, no. 1 (2006): 1–5. http://dx.doi.org/10.2478/cttr-2013-0815.

Full text

Abstract:

AbstractThe effects of X-ray irradiation on mortality and sterility of the cigarette beetle, Lasiodermaserricorne (F.), were studied at doses ranging from 0.05 to 0.2 kGy. Irradiation above 0.1 kGy prevented eggs and larvae from developing to the adult stage. The irradiated larvae remained at the larval or pupal stages for months without further development and ultimately died of desiccation. Irradiation did not affect the viability of pupae and adults but seriously affected their fertility. Females were completely sterilized above 0.1 kGy, although males retained weakened fertility at all dos

APA, Harvard, Vancouver, ISO, and other styles

24

Kwak, LW, MJ Campbell, AD Zelenetz, and R. Levy. "Combined syngeneic bone marrow transplantation and immunotherapy of a murine B-cell lymphoma: active immunization with tumor-derived idiotypic immunoglobulin." Blood 76, no. 11 (1990): 2411–17. http://dx.doi.org/10.1182/blood.v76.11.2411.2411.

Full text

Abstract:

Abstract Recurrence of the underlying malignancy remains a major cause of treatment failure after autologous bone marrow transplantation (BMT) for patients with lymphoma. In this regard, we have developed an immunotherapeutic approach designed to induce resistance against residual tumor cells persisting after BMT. Previous studies in the model system of 38C13, a lethal B-cell lymphoma of C3H origin, have shown that active immunization with purified tumor-derived surface immunoglobulin (Id), as a tumor-associated antigen, produces resistance to tumor growth. Id immunization of lethally irradiat

APA, Harvard, Vancouver, ISO, and other styles

25

Kwak, LW, MJ Campbell, AD Zelenetz, and R. Levy. "Combined syngeneic bone marrow transplantation and immunotherapy of a murine B-cell lymphoma: active immunization with tumor-derived idiotypic immunoglobulin." Blood 76, no. 11 (1990): 2411–17. http://dx.doi.org/10.1182/blood.v76.11.2411.bloodjournal76112411.

Full text

Abstract:

Recurrence of the underlying malignancy remains a major cause of treatment failure after autologous bone marrow transplantation (BMT) for patients with lymphoma. In this regard, we have developed an immunotherapeutic approach designed to induce resistance against residual tumor cells persisting after BMT. Previous studies in the model system of 38C13, a lethal B-cell lymphoma of C3H origin, have shown that active immunization with purified tumor-derived surface immunoglobulin (Id), as a tumor-associated antigen, produces resistance to tumor growth. Id immunization of lethally irradiated mice a

APA, Harvard, Vancouver, ISO, and other styles

26

Traver, David, Alissa Winzeler, Howard M. Stern, et al. "Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation." Blood 104, no. 5 (2004): 1298–305. http://dx.doi.org/10.1182/blood-2004-01-0100.

Full text

Abstract:

Abstract The study of hematopoiesis has been greatly facilitated by transplantation of blood cell populations into recipient animals. Efficient engraftment of donor cells generally requires ablation of the host hematopoietic system. The zebrafish has recently emerged as a developmental and genetic system to study hematopoiesis. To enable the study of hematopoietic stem cell (HSC) biology, immune cell function, and leukemogenesis in zebrafish, we have developed hematopoietic cell transplantation (HCT) into adult recipient animals conditioned by γ irradiation. Dose-response experiments showed th

APA, Harvard, Vancouver, ISO, and other styles

27

Vijay Mala (Grover) Nair, Vijay Mala (Grover) Nair, Akhila M. Akhila M, Ganesh Sanjeev, Prashantha Naik, and Vikram S. Vikram S. "Electron Beam Irradiation – a Potential Inducer of Sperm Abnormalities in Swiss Albino Mouse, Mus Musculus Exposed to Median Lethal Dose." Indian Journal of Applied Research 3, no. 7 (2011): 637–39. http://dx.doi.org/10.15373/2249555x/july2013/201.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Walter, M., K. S. H. Boyd-Wilson, J. H. Perry, and R. A. Hill. "Botrytis tolerance to 6phenylalphapyrone and massoialactone." New Zealand Plant Protection 53 (August 1, 2000): 375–81. http://dx.doi.org/10.30843/nzpp.2000.53.3612.

Full text

Abstract:

The potential for Botrytis populations exposed to UV radiation to develop tolerance to the Trichoderma metabolite 6pentylalphapyrone (6PAP) and the 6PAP analog massoialactone was determined using 14 different Botrytis isolates There was significant isolate variation in germination of Botrytis conidia after UV exposure Plating conidia onto sublethal doses of 6PAP yielded no 6PAP tolerant mutants After UV irradiation two Botrytis mutants grew on normally lethal doses of 6 PAP while 59 mutants grew on normally lethal doses of massoialactone 6PAP mutants were cross resistant to normally lethal dos

APA, Harvard, Vancouver, ISO, and other styles

29

Hashimoto, Atsushi, Jun Sawai, Hideo Igarashi, and Masaru Shimizu. "Irradiation power effect on ir pasteurization below lethal temperature of bacteria." JOURNAL OF CHEMICAL ENGINEERING OF JAPAN 26, no. 3 (1993): 331–33. http://dx.doi.org/10.1252/jcej.26.331.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Zhao, Siming, Chengguang Qiu, Shanbai Xiong, and Xuexun Cheng. "A thermal lethal model of rice weevils subjected to microwave irradiation." Journal of Stored Products Research 43, no. 4 (2007): 430–34. http://dx.doi.org/10.1016/j.jspr.2006.12.005.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Sugimoto, Kenkichi, Yasuhiro Adachi, Keiko Moriyama, et al. "Induction of the Expression of SCF in Mouse by Lethal Irradiation." Growth Factors 19, no. 4 (2001): 219–31. http://dx.doi.org/10.3109/08977190109001088.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

George, K. C., S. A. Hebbar, S. P. Kale, and P. C. Kesavan. "Caffeine protects mice against whole-body lethal dose of gamma-irradiation." Journal of Radiological Protection 19, no. 2 (1999): 171–76. http://dx.doi.org/10.1088/0952-4746/19/2/306.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Huang, Eng-Yen, Chen-Tzu Peng, and Chung-Chih Wang. "Effects of radiation response modifiers given after lethal whole-abdominal irradiation." International Journal of Radiation Biology 94, no. 3 (2018): 289–94. http://dx.doi.org/10.1080/09553002.2018.1431698.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

McDunn, Jonathan E., Jared T. Muenzer, Benjamin Dunne, et al. "An anti-apoptotic peptide improves survival in lethal total body irradiation." Biochemical and Biophysical Research Communications 382, no. 4 (2009): 657–62. http://dx.doi.org/10.1016/j.bbrc.2009.03.080.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Patterson, Andrea M., Pratibha Singh, Hongge Li, et al. "Prostaglandin E2 Promotes Early Bone Marrow Reconstitution for Survival after Lethal Irradiation." Blood 128, no. 22 (2016): 1481. http://dx.doi.org/10.1182/blood.v128.22.1481.1481.

Full text

Abstract:

Abstract Introduction: High dose total body irradiation (TBI) causes severe damage to the hematopoietic system, resulting in ablation of both red and white blood cells and a high probability of infection, hemorrhage, and death. This is known as the hematopoietic syndrome of the acute radiation syndrome (HS-ARS). TBI is used therapeutically, and incidental exposure through nuclear accidents or radical terrorism is a current threat for which preparation is critical. Safe, effective, and pragmatic agents against HS-ARS are needed. We have identified prostaglandin E2 (PGE2) as a promising medical

APA, Harvard, Vancouver, ISO, and other styles

36

Waddick, KG, CW Song, L. Souza, and FM Uckun. "Comparative analysis of the in vivo radioprotective effects of recombinant granulocyte colony-stimulating factor (G-CSF), recombinant granulocyte-macrophage CSF, and their combination." Blood 77, no. 11 (1991): 2364–71. http://dx.doi.org/10.1182/blood.v77.11.2364.2364.

Full text

Abstract:

Abstract The purpose of the present study was to evaluate and compare the in vivo radioprotective effects of pre-total body irradiation (TBI) conditioning with recombinant granulocyte colony-stimulating factor (rG- CSF) and recombinant granulocyte-macrophage CSF (rGM-CSF) in a large series of lethally and supralethally irradiated mice. Also analyzed were the radioprotective effects of simultaneous as well as sequential combinations of rG-CSF and rGM-CSF. Our findings in 1,180 mice provide direct evidence that in vivo administration of rG-CSF or rGM-CSF before TBI protects a significant fractio

APA, Harvard, Vancouver, ISO, and other styles

37

Waddick, KG, CW Song, L. Souza, and FM Uckun. "Comparative analysis of the in vivo radioprotective effects of recombinant granulocyte colony-stimulating factor (G-CSF), recombinant granulocyte-macrophage CSF, and their combination." Blood 77, no. 11 (1991): 2364–71. http://dx.doi.org/10.1182/blood.v77.11.2364.bloodjournal77112364.

Full text

Abstract:

The purpose of the present study was to evaluate and compare the in vivo radioprotective effects of pre-total body irradiation (TBI) conditioning with recombinant granulocyte colony-stimulating factor (rG- CSF) and recombinant granulocyte-macrophage CSF (rGM-CSF) in a large series of lethally and supralethally irradiated mice. Also analyzed were the radioprotective effects of simultaneous as well as sequential combinations of rG-CSF and rGM-CSF. Our findings in 1,180 mice provide direct evidence that in vivo administration of rG-CSF or rGM-CSF before TBI protects a significant fraction of mice

APA, Harvard, Vancouver, ISO, and other styles

38

Zhang, Benyue, Damilola Oyewole-Said, Jun Zou, Ifor R. Willliams, and Andrew T. Gewirtz. "TLR5 signaling in murine bone marrow induces hematopoietic progenitor cell proliferation and aids survival from radiation." Blood Advances 1, no. 21 (2017): 1796–806. http://dx.doi.org/10.1182/bloodadvances.2017006981.

Full text

Abstract:

Key Points Flagellin activates TLR5 signaling in mouse bone marrow and induces hematopoietic progenitor cell proliferation. Flagellin-induced MPP3 cells aid the survival of mice exposed to lethal irradiation.

APA, Harvard, Vancouver, ISO, and other styles

39

Monikasari, Intan Novela Setya, Syaiful Anwar, and Budi Adi Kristanto. "KERAGAMAN M1 TANAMAN HIAS BUNGA MATAHARI (Helianthus annuus L.) AKIBAT IRADIASI SINAR GAMMA." Journal of Agro Complex 2, no. 1 (2018): 1. http://dx.doi.org/10.14710/joac.2.1.1-11.

Full text

Abstract:

ABSTRACT The purpose of the research was to obtain the morphological variability of M1 sunflower ornamental plant and information of lethal doses (LD50) effect of mutation by gamma ray irradiation. The research was arranged in monofactor experimental with Completely Randomized Design (RAL) with 5 treatments and 5 replication, each replication consisted of 5 sunflower seeds was irradiated by gamma ray of 0, 5, 25, 45, and 65 Gy. The data observed were analyzed by anova and followed with BNT of 5% level. Parameters observed included germination, plant height, stem diameter, tube flower diameter,

APA, Harvard, Vancouver, ISO, and other styles

40

Blazar, BR, PA Taylor, A. Panoskaltsis-Mortari, TA Barrett, JA Bluestone, and DA Vallera. "Lethal murine graft-versus-host disease induced by donor gamma/delta expressing T cells with specificity for host nonclassical major histocompatibility complex class Ib antigens." Blood 87, no. 2 (1996): 827–37. http://dx.doi.org/10.1182/blood.v87.2.827.bloodjournal872827.

Full text

Abstract:

Although T-cell receptor (TCR) alpha/beta expressing cells have a well- known role in graft-versus-host disease (GVHD) generation, the role of TCR gamma/delta expressing cells in this process has remained unclear. To elucidate the potential function of TCR gamma/delta cells in GVHD, we have used transgenic (Tg) H-2d mice (termed G8) that express gamma/delta heterodimers on a high proportion of peripheral T cells. In vitro, G8 Tg gamma/delta T cells proliferate to and kill C57BL/6 (B6) (H-2b) which express gene products (T10b and T22b) from the nonclassical major histocompatibility complex (MHC

APA, Harvard, Vancouver, ISO, and other styles

41

Howell, Roger W., S. Murty Goddu, Anupam Bishayee, and Dandamudi V. Rao. "Radioprotection against Lethal Damage Caused by Chronic Irradiation with Radionuclides In Vitro." Radiation Research 150, no. 4 (1998): 391. http://dx.doi.org/10.2307/3579657.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Thompson, J. S., R. Asmis, Y. Chu, J. Glass, B. Nelson, and S. A. Brown. "Amifostine prior to lethal irradiation prevents allogeneic bone marrow engraftment in mice." Bone Marrow Transplantation 41, no. 11 (2008): 927–34. http://dx.doi.org/10.1038/sj.bmt.1705995.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Geyeregger, R., C. Freimüller, J. Stemberger, G. Fischer, V. Witt, and G. Fritsch. "Human AdV-specific T cells: persisting in vitro functionality despite lethal irradiation." Bone Marrow Transplantation 49, no. 7 (2014): 934–41. http://dx.doi.org/10.1038/bmt.2014.86.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Denkins, Y. M., and M. L. Kripke. "EFFECT OF UV IRRADIATION ON LETHAL INFECTION OF MICE WITH Candida albicans." Photochemistry and Photobiology 57, no. 2 (1993): 266–71. http://dx.doi.org/10.1111/j.1751-1097.1993.tb02285.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Labarère, Jacques, and Gérard Barroso. "Lethal and mutation frequency responses of Spiroplasma citri cells to UV irradiation." Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 210, no. 1 (1989): 135–41. http://dx.doi.org/10.1016/0027-5107(89)90052-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Araujo, Paula Z., Oscar J. Oppezzo, Jorge A. Ibáñez, Miguel Blesa, and Ramón A. Pizarro. "Factors Capable of Modifying the Response of Pseudomonas aeruginosa to the Inactivation Induced by Heterogeneous Photocatalysis." International Journal of Chemical Reactor Engineering 11, no. 2 (2013): 773–79. http://dx.doi.org/10.1515/ijcre-2012-0037.

Full text

Abstract:

Abstract The heterogeneous photocatalysis (HP) procedure has been demonstrated to be an interesting method for disinfecting water. It is effective for inactivating Pseudomonas aeruginosa, but its effectiveness may be reduced due to the action of several factors which are able to affect bacterial radio-sensitivity. The results reported here show the influence of nutritional stress and pre-exposure to sub-lethal UVA doses on the efficiency of the inactivation of P. aeruginosa by HP. Both previous exposures to low UVA fluencies and nutrient deprivation induce bacterial resistance to this process,

APA, Harvard, Vancouver, ISO, and other styles

47

Babb, Rachelle, Austen Chen, Timothy R. Hirst та ін. "Intranasal vaccination with γ-irradiated Streptococcus pneumoniae whole-cell vaccine provides serotype-independent protection mediated by B-cells and innate IL-17 responses". Clinical Science 130, № 9 (2016): 697–710. http://dx.doi.org/10.1042/cs20150699.

Full text

Abstract:

We have generated a killed Streptococcus pneumoniae whole bacterial cell vaccine, by exposing the bacteria to γ-irradiation. The non-adjuvanted γ-irradiated pneumococcal vaccine provides protection against lethal infection by S. pneumoniae strains of different capsular serotypes.

APA, Harvard, Vancouver, ISO, and other styles

48

Kuna, Pavel, Milan Dostál, Otakar Neruda, et al. "Radioprotective Effects of Amifostine (WR-2721) or Cystamine on Radiation Damage and Its Repair in Rats Whole Body Exposed to Fission Neutrons." Acta Medica (Hradec Kralove, Czech Republic) 47, no. 1 (2004): 19–23. http://dx.doi.org/10.14712/18059694.2018.60.

Full text

Abstract:

Sulphur containing radioprotective drugs amifostine (gammaphos, WR-2721) or cystamine (disulfide of meracaptoethylamine) of Czechoslovak production were examined in whole body fission neutrons irradiated rats in the thermal column of reactor VVR-S. Using the split-dose technic the first sublethal neutron dose in the range 1–2 Gy was followed by second lethal exposures in the two time intervals (3 or 6 days) using whole body fission neutrons irradiations (3 days interval) or whole body γ-irradiations (6 days interval) for LD50/30 evaluation within next 30 days survival observation. In other exp

APA, Harvard, Vancouver, ISO, and other styles

49

Yamaguchi, Masaru, Tokuhisa Hirouchi, Mitsuru Chiba, et al. "Thrombopoietin-Mimetic Romiplostim Confers the Complete Survival Rate to Mice Exposed to Lethal Ionizing Radiation." Blood 126, no. 23 (2015): 2390. http://dx.doi.org/10.1182/blood.v126.23.2390.2390.

Full text

Abstract:

Abstract Radiation-related casualties following exposure to a lethal dose of ionizing radiation show severe acute radiation syndromes (ARS) involving bone marrow death and gastrointestinal death. ARS cause decreases in red blood cell count, white blood cell count, platelet count and gastrointestinal dysfunction, finally leading to death caused by systemic bleeding. Therefore, reconstitution and restoration of hematopoiesis is a top priority. Although bone marrow transplantation (BMT) is also available for recovery from radiation-induced bone marrow damage, BMT for victims in radiation accident

APA, Harvard, Vancouver, ISO, and other styles

50

HIXON, J. "Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut." Biology of Blood and Marrow Transplantation 8, no. 6 (2002): 316–25. http://dx.doi.org/10.1016/s1083-8791(02)50029-x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!