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Journal articles on the topic 'Leucocyte count ratio'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

P. G., Naveen, and K. Veena L. Karanth. "Derived neutrophil by lymphocytes ratio is a misnomer, implication of derived leucocytes ratio in diagnosing gastric cancers." International Surgery Journal 6, no. 1 (2018): 82. http://dx.doi.org/10.18203/2349-2902.isj20185187.

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Background: Gastric malignant neoplasms are well-known common malignant disease seen in routine clinical practice. In India incidence are comparatively low but accounts for significant mortality and morbidity. Gastric malignancy incidence adds significant numbers every year to cancer related deaths worldwide. And prognosis is not satisfactory in spite of medical innovations and technological advancements. Early diagnosis helps for successful surgical removal of gastric cancer and to achieve a curative resections. Present study objectives are to solve the paradox of misnomer derived neutrophil

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2

Sajjad, Zunera, Sunila Tashfeen, Samrah Shahid, et al. "Correlation of Total Leucocyte Count, Neutrophil to Lymphocyte Ratio and Platelet Count with Duration of Hospital Stay in Dengue Fever." Life and Science 6, no. 1 (2025): 06. https://doi.org/10.37185/lns.1.1.466.

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Objective: To assess the correlation of total leucocyte count (TLC), neutrophil to lymphocyte ratio (NLR), and platelet count with the duration of hospital stay in dengue patients.Study Design: A cross-sectional study.Place and Duration of Study: The study was conducted at the Department of Haematology and Dengue Ward, Pak Emirates Military Hospital (PEMH) Rawalpindi, Pakistan from January 2023 to February 2023.Methods: Comprised 136 confirmed dengue-positive patients who were admitted to PEMH with symptoms of fever. All the participants were requested for their informed consent before their e

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Made Wulan Utami Dewi, IB Kade Satyagraha, Ni Nyoman Wahyuni, Tjok Istri Parwati, and Ratna Kartika. "Correlation of Neutrophil-Lymphocyte Ratio with the Evidence of Stroke Haemorrhagic at Tertiary Hospitals." WMJ (Warmadewa Medical Journal) 8, no. 2 (2023): 58–63. http://dx.doi.org/10.22225/wmj.8.2.7988.58-63.

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Stroke is the leading cause of death, disability, and morbidity in the world. Hemorrhagic stroke (HS) prevalence accounts for 10–20% of all strokes, whereas ischemic stroke accounts for 85 percent. Clinical manifestation and numerous biomarkers such as ferritin level, cholesterol level, and lately neutrophil-to-lymphocyte ratio have been suggested as a sign of HS prognosis. It’s also used as a modality for differentiating ischemia from hemorrhagic. The purpose of this study is to assess if there is a link between NLR and HS evidence. A retrospective cross-sectional study was conducted among th

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Ndrepepa, Gjin, Siegmund Braun, Raisuke Iijima, et al. "Total leucocyte count, but not C-reactive protein, predicts 1-year mortality in patients with acute coronary syndromes treated with percutaneous coronary intervention." Clinical Science 116, no. 8 (2009): 651–58. http://dx.doi.org/10.1042/cs20080298.

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Although an association between elevated leucocyte count and mortality in patients with ACS (acute coronary syndromes) has been established, the independence of this association from coronary risk factors and C-reactive protein has been inadequately studied. In the present study, this prospective registry included 4329 patients with ACS treated with PCI (percutaneous coronary intervention): 1059 patients with STEMI [ST-segment elevation MI (myocardial infarction)], 1753 patients with NSTEMI (non-STEMI) and 1517 patients with unstable angina. Blood samples were obtained before angiography for l

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Akshay, Louis Dias, and D. Sumanth. "Usefulness of Various Peripheral Blood Leukocyte Count ratios in Malaria Evaluation." International Journal of Health Sciences and Pharmacy (IJHSP) 1, no. 2 (2017): 52–60. https://doi.org/10.5281/zenodo.1043523.

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Malaria is a major public health problem in India. Changes in blood cell counts are a well-known feature of malaria. Hence an attempt has been made to assess the role of leucocyte ratios in malaria as predictors of malaria infection and its clinical severity. <strong>Methods:</strong> A retrospective observational cohort study was carried out in a tertiary care teaching hospital over a period of 2 months. A total of 171 samples and 48 controls were included in the study. All the absolute and differential white blood cell counts were done. The neutrophil-lymphocyte count ratio (NLCR), monocyte-

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Castillo Martinez, Daniel Benito, Doris Michelle Palacios Rivera, Juan Antonio Clemente Castillo, Karla Itzell Altamirano Moreno, Luis Daniel De los Cobos Duran, and Alejandro Aragón Montes. "Granulocyte to monocyte ratio: leucokinetics in hematic biometry for appendicitis screening." International Journal of Research in Medical Sciences 11, no. 2 (2023): 497–501. http://dx.doi.org/10.18203/2320-6012.ijrms20230159.

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Background: Acute appendicitis diagnosis is still challenging and is established with clinical history, physical exam, laboratory tests, and imaging studies. It´s crucial to analyze the blood biometry with physiopathological asses and not with a statistical approach for establishing diagnostic items. The interaction between neutrophils with monocytes is noticeable in the blood biometry, so its relationship could be explained as directly proportional to the neutrophils count because of cellular recruitment and inversely proportional to the monocyte count because of cellular migration. Methods:

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Tugiyanti, E., Z. Zuprizal, R. Rusman, T. Yuwanta та I. Ismoyowati. "EFFECT OF α-TOCOPHEROL AND ASCORBIC ACIDS ON PERFORMANCE AND BLOOD IMMUNITY PROFILE OF MALE NATIVE MUSCOVY DUCK". Journal of the Indonesian Tropical Animal Agriculture 41, № 3 (2016): 145–52. http://dx.doi.org/10.14710/jitaa.41.3.145-152.

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The purpose of the research was to assess the effect of α-tocopherol and ascobic acids on the performance and immunity blood profile of male native Muscovy duck. The materials used were 84 male Muscovy ducks at 9 weeks old. The research used completely randomized design with 7 treatments. The treatments were E0C0 : basal diet without α-tocopherol and ascobic acids, E400: basal diet+ α-tocopherol 400IU, E600: basal diet+α-tocopherol 600IU, C400: basal diet+ascorbic acid 400mg/kg, C600: basal diet+ascorbic acid 600mg/kg, E200C200: basal diet+α-tocopherol 200IU+ ascorbic acid 200mg/kg, and E300C3

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Sravani, Ponnada, Sarat Srinivas Kukkala Saraswathi, Balaji Chowdari, and Neeli Divyasree. "Study of Effect of Hematological Parameters in Malaria Infection-Our Experience in a Tertiary Care Centre." International Journal of Pharmaceutical and Clinical Research 16, no. 1 (2024): 776–85. https://doi.org/10.5281/zenodo.11100484.

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<strong>Background:</strong> Malaria is a significant health problem in India, being one of the biggest burdens in terms of morbidity and mortality. The mortality rate is high in severe malaria (10-30%), and hematological changes play a crucial role in morbidity and mortality. Monocytes, neutrophils, and lymphocytes play a vital role in the induction of immune responses to malaria infection and their parameters have been proven as predictors of malaria infection and its clinical severity. <strong>Materials and Methodology:</strong> This study was done for a period of 2 years i.e

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Kurian, Amrita, Poornima H, and Abdul Salam. "Association of Total Leucocyte Count and Neutrophil to Lymphocyte Ratio with Short Term Major Adverse Cardiac Events after Acute ST Elevation Myocardial Infarction in a Tertiary Care Centre in South India." Galore International Journal of Health Sciences and Research 8, no. 2 (2023): 27–34. http://dx.doi.org/10.52403/gijhsr.20230206.

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Ischemic Heart Disease is a global health issue with developing countries bearing the brunt of the burden. The development of adverse cardiac events after an acute coronary event further aggravates the morbidity and mortality. In a developing country like India, employing inexpensive markers such as Total Leucocyte Count (TLC) and Neutrophil to Lymphocyte Ratio (NLR) can greatly aid prognostication in acute myocardial infarction. The study aimed at estimating the association of TLC and NLR with short term Major Adverse Cardiac Events (MACE) after acute STEMI. We also studied the association of

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Sanchez, P. L., J. L. Morinigo, P. Pabon, et al. "Prognostic relations between inflammatory markers and mortality in diabetic patients with non-ST elevation acute coronary syndrome." Heart 90, no. 3 (2004): 264–69. http://dx.doi.org/10.1136/hrt.2002.007443.

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Objective: To determine the differences in the inflammatory status between diabetic and non-diabetic patients and to evaluate the usefulness of C reactive protein, fibrinogen, and leucocyte count as predictors of death in diabetic patients with unstable coronary disease.Design: Nested case-control comparisons of the inflammatory status between diabetic and non-diabetic patients. Prospective cohort analysis of C reactive protein concentration, fibrinogen concentration, and leucocyte count as predictors of cardiovascular death in diabetic patients.Setting: Coronary care unit in Spain.Participant

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Örmen, M., ÖG Doruk, H. Gözgöz, et al. "Leucocyte Volume, Conductivity, and Scatter at Presentation in COVID-19 Patients." Nigerian Journal of Clinical Practice 26, no. 6 (2023): 771–78. http://dx.doi.org/10.4103/njcp.njcp_737_22.

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ABSTRACT Background: In COVID-19 patients, besides changes in leucocyte count, morphological abnormalities of circulating blood cells have been reported. Aim: This study aims to investigate the relationship between the morphological and functional properties of leucocytes and the severity of the disease in COVID-19 patients. Materials and Methods: Blood samples were collected from COVID-19 patients (n = 130) at the time of admission. The patients were stratified according to the comorbidity, age, LDH, lymhocyte count score as mild, moderate, and severe. Complete blood count and the cell popula

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Meirina, Fathia, Bidasari Lubis, Tiangsa Sembiring, Nelly Rosdiana, and Olga Siregar. "Hematological scoring system as an early diagnostic tool for neonatal sepsis." Paediatrica Indonesiana 55, no. 6 (2016): 315. http://dx.doi.org/10.14238/pi55.6.2015.315-21.

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Background Sepsis was the leading cause of death in babies by30%-50% in developing countries. Early diagnosis of neonatalsepsis is still a difficult problem because of clinical features are notspecific. Blood culture is the gold standard, but it takes several daysand is expensive. The hematological scoring system (HSS) consistsof hematologic parameters (leucocyte count, polymorphonuclear(PMN) cells, degenerative changes, and platelet count) for earlydiagnosis of neonatal sepsis.Objective To measure HSS as an early diagnostic tool for neonatalsepsis.Methods A cross sectional study was conducted

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Mateu-de Antonio, Javier, Santiago Grau, Sonia Luque, Mónica Marín-Casino, Inmaculada Albert, and Esther Ribes. "Comparative effects of olive oil-based and soyabean oil-based emulsions on infection rate and leucocyte count in critically ill patients receiving parenteral nutrition." British Journal of Nutrition 99, no. 4 (2007): 846–54. http://dx.doi.org/10.1017/s0007114507837433.

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Soyabean oil-based emulsions high in linoleic acid used in parenteral nutrition (PN) could interfere with immune function and may increase the risk of septic complications. Olive oil-based emulsions, high in oleic acid, could have fewer immune effects. We compared the effects of a soyabean oil-based emulsion v. an olive oil-based emulsion on infection rate, appearance of new infection episodes, leucocyte count (peak and evolution), acute-phase proteins, and major health outcomes in intensive care unit (ICU) adult patients receiving PN. The study was designed as an observational, retrospective,

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Gebhard, Catherine, Aurel Toma, Zhao Min, et al. "Preprocedural Leucocyte Count Predicts Risk in Patients with Coronary Chronic Total Occlusion." Thrombosis and Haemostasis 117, no. 11 (2017): 2105–15. http://dx.doi.org/10.1160/th17-06-0381.

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Background As technologies of percutaneous coronary intervention (PCI) for coronary chronic total occlusions (CTO) have improved, great uncertainty exists regarding patient selection and long-term benefit of CTO-PCI. Given that white blood cell (WBC) count has been associated with cardiovascular risk, we hypothesized that the latter might provide incremental prognostic value in patients undergoing CTO-PCI. Methods and Results Our study population consisted of 1,262 consecutive patients (76.3% males, mean age of 67.7 ± 10.3 years) who underwent elective PCI at our centre between January 2002 an

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Hendrianingtyas, Meita, and MI Tjahjati DM. "LEUKOSIT INFEKSI BAKTERI SISTEMIK." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 17, no. 3 (2018): 155. http://dx.doi.org/10.24293/ijcpml.v17i3.1094.

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Patients in intensive care unit (ICU) have a high risk for systemic bacterial infection. Serum procalcitonin (PCT) known as a markerto predict bacterial infection, systemic inflammation responsse (SIRS) or sepsis. Another simple and easy indicator is by using leucocytecount-differential count, absolute neutrophyl count (ANC), and immatur/total (I/T) neutrophyl ratio. The aim of this study was toknow the comparation of the leucocyte count-differential count, ANC, and I/T ratio with procalcitonin serum value in patients suspectto systemic bacterial infection at ICU. A cross sectional study on 20

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Kallur, Jayalaxmi Yadav, Indira Priyadarshini Anubrolu, Shridevi S. H, and Bharath C. "Clinico-haematological profile in COVID-19 patients: an observational study at tertiary care center." Journal of Pathology of Nepal 11, no. 2 (2021): 1806–12. http://dx.doi.org/10.3126/jpn.v11i2.35080.

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Background: It is known as in other viral infections, severe acute respiratory syndrome coronavirus 2 infections, can be associated with haematological changes and often has the potential to optimize the monitoring of the infectious process and their severity. Hence, we took up this study to analyze clinico-haematological profiles in coronavirus disease-2019 patients and to compare haematological changes between mild, moderate, and severe cases. Materials and methods: The study included the patients who were tested positive for coronavirus disease-2019 infection and the patients were classifie

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Soni, Amit, Dharmendra K. Pipal, Anupam Bhargava, et al. "Role of leucocytosis, hyperbilirubineamia, decreased mean platelet volume and increased international normalized ratio in prediction of complicated appendicitis." International Surgery Journal 8, no. 6 (2021): 1804. http://dx.doi.org/10.18203/2349-2902.isj20212275.

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Background: A diagnostic approach for complicated appendicitis is still controversial. We analyzed the preoperative laboratory markers that may predict complicated appendicitis.Methods: To study the role of leukocytosis, hyperbilirubinemia, decreased mean platelet volume (MPV) and increased international normalized ratio (INR) in the prediction of complicated appendicitis. Total 60 patients were enrolled and divided them into 2 groups, un-complicated (AUA) and complicated (ACA) acute appendicitis, each having 30 cases.Results: Total leucocyte count (TLC) >10000 mm³ was found in 70% of AUA c

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Biolo, Gianni, Nicola Fiotti, Franco Cominotto, et al. "Ruling Out Coronavirus Disease 2019 in Patients with Pneumonia: The Role of Blood Cell Count and Lung Ultrasound." Journal of Clinical Medicine 10, no. 16 (2021): 3481. http://dx.doi.org/10.3390/jcm10163481.

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Coronavirus disease 2019 (COVID-19) is characterized by a distinctive blood leucocyte pattern and B-lines on lung ultrasound (LUS) as marker of alveolar-interstitial syndrome. We aimed to evaluate the accuracy of blood leucocyte count alone or in combination with LUS for COVID-19 diagnosis. We retrospectively enrolled consecutive patients diagnosed with community acquired pneumonia (CAP) at hospital admission to derive and validate cutoff values for blood cell count that could be predictive of COVID-19 before confirmation by the nucleic acid amplification test (NAAT). Cutoff values, generated

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Dadzie, Isaac, Elvis Quansah, Mavis Puopelle Dakorah, Victoria Abiade, Ebenezer Takyi-Amuah, and Richmond Adusei. "The Effectiveness of Dipstick for the Detection of Urinary Tract Infection." Canadian Journal of Infectious Diseases and Medical Microbiology 2019 (October 23, 2019): 1–6. http://dx.doi.org/10.1155/2019/8642628.

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Background. The balance between the choices of UTI diagnostic tools in most primary care settings has been settled for by the more rapid, less labour-intensive dipstick. This study aimed to evaluate the effectiveness of dipstick for diagnosing UTI. Method. A total of 429 urine samples were collected from patients suspected of UTI; cultured on cysteine-lactose-electrolyte-deficient (CLED) agar, blood agar, and MacConkey agar; and incubated at 37°C overnight. Urine cultures with bacteria count ≥105 cfu/ml were classified as “positive” for UTI. A dipstick was used to screen for the production of

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Iqbal, Mohammad Faruq, Arif Imtiyaz Chowdhury, and Sharkar Rushdi Aziz. "Role of C-reactive Protein, Leucocyte and Neutrophil Count in Diagnosis of Acute Appendicitis." Journal of Armed Forces Medical College, Bangladesh 17, no. 1 (2022): 26–29. http://dx.doi.org/10.3329/jafmc.v17i1.56717.

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Introduction: Acute appendicitis is the most common cause of surgical acute abdomen and appendicectomy is the most commonly done surgery. Accurate preoperative diagnosis can reduce negative appendicectomy rate. Objective: To evaluate the diagnostic accuracy of C-reactive protein (CRP), total leucocyte count (TLC) and neutrophil count in patients operated after clinical diagnosis of acute appendicitis. Materials and Methods: This cross-sectional observational study was conducted among 100 patients at Combined Military Hospital, Dhaka from August 2012 to January 2013. Serum CRP level was measure

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Väisänen, Sari, Rainer Rauramaa, IIkka Penttilä, et al. "Variation in Plasma Fibrinogen over One Year: Relationships with Genetic Polymorphisms and Non-genetic Factors." Thrombosis and Haemostasis 77, no. 05 (1997): 0884–89. http://dx.doi.org/10.1055/s-0038-1656072.

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SummaryWe analyzed plasma fibrinogen level in relation to genetic polymorphisms in the a- and β-fibrinogen gene loci. Furthermore, the association of other CVD risk markers with fibrinogen was studied twice, with a time interval of one year in 50 to 60 year old men (n = 183). DNA polymorphisms were detected by PCR and digestion with TaqI (α-fibrinogen), Hind III and Bcl I (β-fibrinogen) restriction enzymes. The correlation coefficient between fibrinogen measurements was 0.48 (p <0.001). Blood leucocytes and waist-to-hip circumference ratio were the strongest correlates of fibrinogen level i

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Yılmaz, Necat, and Ayşe Binnur Erbağcı. "Evaluation of Erythrocyte G6PD Activity Unit; It is Better Defined as a Function of RBC Count." European Journal of Therapeutics 10, no. 1, 2 (1999): 58–63. http://dx.doi.org/10.58600/eurjther.1999-10-1-2-1520-arch.

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Glucose 6-phosphate dehydrogenase (G6PD) deficiency, one of the most common red celi abnormalities, is characterized by wide clinical, biochemical and molecular heterogeneity. in clinical laboratories erythrocyte ·G6PD activity is defined either as a function of hemoglobin (Hb) concentration or red blood celi (RBC) count and seldom hematocrit (Hct). These parameters are variable tor every individual and misinterpretation of the results cannot be avoided with reference interval establishment studies unless the best approach that define erythrocyte G6PD activity is selected. Hb concentration is

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Ali, Kamran, Khurram Haq Nawaz, Wahaj Ul Hassan, and Raja Muhammad Waqar. "Absolute Lymphocyte Count; the most Sensitive Indicator of the Risk of Progression and Complications in COVID-19." Pakistan Armed Forces Medical Journal 73, no. 4 (2023): 1116–19. http://dx.doi.org/10.51253/pafmj.v73i4.6705.

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Objective: To explore the role of lymphocyte count as a predictor of severity biomarkers in COVID-19 patients. Study Design: Comparative cross-sectional study. Place and Duration of Study: Pak Emirates Military Hospital, Rawalpindi Pakistan, from Sep 2020 to Jan 2021. Methodology: A total of 120 patients were enrolled for this study. We analyzed the blood samples of the affected patient in a certified laboratory. From blood samples, we deduced information related to leucocyte count, neutrophils, lymphocyte (cells×109/L) counts, ferritin (ng/mL), CRP (mg/dL), d-Dimer (mg/mL),

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Malvat, Z., S. A. Lynch, A. Bennison, and M. Jessopp. "Evidence of links between haematological condition and foraging behaviour in northern gannets ( Morus bassanus )." Royal Society Open Science 7, no. 5 (2020): 192164. http://dx.doi.org/10.1098/rsos.192164.

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Haematological analyses can reveal the physiological condition of birds, which are known to efficiently disguise symptoms of stress and disease. However, the interpretation of such analyses requires species-specific baseline data, which are lacking for most free-living seabird species. We provide baseline reference data for several haematological parameters in northern gannets ( Morus bassanus ) and combine this with telemetry and dietary data to understand the links between haematological condition and foraging behaviour. Blood samples were collected from breeding northern gannets in July 201

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Garudadwiputra, Ian A., Lothar M. M. V. Silalahi, and Widya C. Manus. "HEMORRHAGIC STROKE PROFILE ON SALATIGA REGIONAL PUBLIC HOSPITAL PATIENTS." Journal of Widya Medika Junior 4, no. 1 (2022): 21–33. http://dx.doi.org/10.33508/jwmj.v4i1.3584.

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Introduction: There is an increasing number of new hemorrhagic stroke cases from 2017 to 2018 on The Province of Central Java and Salatiga. A study of demographics, laboratory examination, radiology, outcome, risk factor, and clinical presentation on hemorrhagic stroke patients are rarely done at Salatiga Regional Public Hospital. Objectives: This study aims to describe the hemorrhagic stroke profile on Salatiga Regional Public Hospital patients. Materials and Methods: Hemorrhagic stroke inpatient of Salatiga Regional Public Hospital in the period between October 2018 and October 2019 is studi

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Wascher, Claudia A. F., Josef Hemetsberger, Kurt Kotrschal, and Didone Frigerio. "Leucocyte Profiles and Family Size in Fledgling Greylag Geese (Anser Anser)." Avian Biology Research 10, no. 4 (2017): 246–52. http://dx.doi.org/10.3184/175815617x15036738758871.

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In precocial species, large brood sizes are usually considered as beneficial and individuals in larger broods grow faster and are more dominant compared to individuals in small broods. However, little is known whether family size also beneficially affects the offspring's physiology. In the present study, we investigated whether leucocyte profiles in fledgling Greylag Geese ( Anser anser) are affected by (1) family size, (2) individual characteristics, i.e. age, body condition or sex, or (3) characteristics of the parents, i.e. previous reproductive success. From spring 2013 to autumn 2015, we

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Arıcıgil, Mitat, Mehmet Akif Dündar, Abitter Yücel, Hamdi Arbağ, and Suhayb Kuria Aziz. "Can Platelet and Leukocyte Indicators Give Us an Idea about Distant Metastasis in Nasopharyngeal Cancer?" Prague Medical Report 118, no. 1 (2017): 49–59. http://dx.doi.org/10.14712/23362936.2017.5.

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This study aimes to evaluate platelet and leucocyte indicators, such as the mean platelet volume, platelet distribution width, plateletcrit, white blood cell count, neutrophil to lymphocyte ratio in nasopharyngeal cancer patients and also to evaluate the relationship between these indicators and nasopharyngeal cancer with distant metastasis. The medical records of 118 patients diagnosed with nasopharyngeal cancer in our hospital between January 2006 and August 2015 were reviewed. The nasopharyngeal cancer group was further sub grouped according to the presence or absence of distant metastasis

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Katuwal, Binit, and Sushil Kumar Shilpakar. "The prognostic value of neutrophil-lymphocyte ratio in acute pancreatitis." Journal of Society of Surgeons of Nepal 18, no. 3 (2016): 27. http://dx.doi.org/10.3126/jssn.v18i3.15290.

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Introduction and objective: Acute Pancreatitis (AP) is one of the leading causes of morbidity and mortality worldwide. In approximately a third of the patient with acute pancreatitis, severe pancreatitis may develop, producing progressive organ dysfunction caused by a systemic inflammatory response syndrome (SIRS). This study aimed to determine the correlation between Neutrophil Lymphocyte Ratio (NLR) and the severity of AP.Materials and Methods: All patients admitted in the Surgical Ward of Tribhuvan University Teaching Hospital with the diagnosis of AP were studied prospectively over a perio

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Punatar, Sachin, Lingaraj Nayak, Avinash Bonda, et al. "Ratio of total leukocyte count to C-reactive protein: does it help to differentiate infectious fever from engraftment fever in patients undergoing autologous hematopoietic stem cell transplant?" Cellular Therapy and Transplantation 9, no. 2 (2020): 40–46. http://dx.doi.org/10.18620/ctt-1866-8836-2020-9-2-40-46.

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Engraftment fever (EF) is a common complication of autologous HSCT (AHSCT). It is difficult to discern it from infectious fever (IF). We studied the significance of total blood leucocyte count (TLC) to C-reactive protein (CRP) ratio in differentiating EF from IF. 109 consecutive AHSCT patients were retrospectively analysed between March 2011 and August 2013. Breakthrough fever (BF) was defined as new-onset fever preceded by an afebrile period of at least 48 hours. The BF episodes were classified as IF or EF. Infectious fever was diagnosed in case of blood culture positivity, radiological signs

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Pociute, Aiste, Muhammed Fazil Kottilingal Farook, Algirdas Dagys, Rimantas Kevalas, Goda Laucaityte, and Lina Jankauskaite. "Platelet-Derived Biomarkers: Potential Role in Early Pediatric Serious Bacterial Infection and Sepsis Diagnostics." Journal of Clinical Medicine 11, no. 21 (2022): 6475. http://dx.doi.org/10.3390/jcm11216475.

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Fever is the most common complaint of children who are attending a pediatric emergency department (PED). Most of the fever cases are of viral origin; however, the most common markers, such as leucocyte, neutrophil count, or C-reactive protein, are not sensitive or specific enough to distinguish the etiology of fever, especially if children present at the early phase of infection. Currently, platelets have been attributed a role as important sentinels in viral and bacterial infection pathogenesis. Thus, our aim was to analyze different platelet indices, such as PNLR (platelet-to-neutrophil/lymp

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Zhang, Wen, Chuanwei Li, Yu Xu, et al. "Hyperglycemia and Correlated High Levels of Inflammation Have a Positive Relationship with the Severity of Coronavirus Disease 2019." Mediators of Inflammation 2021 (March 18, 2021): 1–9. http://dx.doi.org/10.1155/2021/8812304.

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Objective. Coronavirus disease 2019 (COVID-19) is a considerable global public health threat. This study sought to investigate whether blood glucose (BG) levels or comorbid diabetes are associated with inflammatory status and disease severity in patients with COVID-19. Methods. In this retrospective cohort study, the clinical and biochemical characteristics of COVID-19 patients with or without diabetes were compared. The relationship among severity of COVID-19, inflammatory status, and diabetes or hyperglycemia was analyzed. The severity of COVID-19 in all patients was determined according to

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Naseer, Nauman, Taimur Khalil Sheikh, Sughra Zulfiqar, Huma Bashir, Sadaf Haroon, and Junaid Jahangir. "Neutrophil Lymphocyte Ratio as Screening Tool for Neonatal Sepsis in Developing Countries." Pakistan Armed Forces Medical Journal 73, no. 2 (2023): 583–86. http://dx.doi.org/10.51253/pafmj.v73i2.8450.

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Objective: to recognize an alternate method for screening neonatal sepsis in patients while considering the sensitivity and accuracy of the diagnosis. Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital, Rawalpindi Pakistan, from Jun to Dec 2021. Methodology: Patients admitted to the Neonatal Intensive Care Unit of the Combined Military Hospital were included in the study. Demographic data, including age, weight, gender, and gestational age, were recorded. In addition, a statistical comparison of total leucocyte count, absolute neutrop

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Sarenac Vulovic, Tatjana, Katarina Cupic, Nenad Petrovic, et al. "Routine Blood Examination Predicts the Course of Disease in Patients with Pseudoexfoliation." Medicina 61, no. 4 (2025): 652. https://doi.org/10.3390/medicina61040652.

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Background and Objectives: Is it possible to predict the course of disease in patients with pseudoexfoliation based on blood examination? Materials and Methods: This retrospective study included 800 patients recruited for cataract surgery in the Clinic of Ophthalmology, University Clinical Centre Kragujevac, Serbia. The patients were divided into four groups: pseudoexfoliation syndrome early stage group (n = 200 patients), pseudoexfoliation syndrome late stage group (n = 200 patients), pseudoexfoliation glaucoma group (n = 200 patients) and the control group (n = 200 patients). During the preo

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Shukla, Gagandeep, Prachi Goyal, and Sunil Arya. "Diagnostic Accuracy of Haematological Scoring System in Paired cord Blood and Peripheral Venous Blood for early Detection of Neonatal Sepsis – A Prospective Analytical Study." Journal of Nepal Paediatric Society 43, no. 1 (2023): 15–21. http://dx.doi.org/10.60086/jnps483.

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Introduction: Sepsis is one of the major causes of neonatal morbidity and mortality. Early recognition and diagnosis of early onset neonatal sepsis (EONS) is difficult. Hence, there is a need for early predictive screening method for EONS, for which Haematological Scoring System (HSS) is used. It comprises of total leucocyte count, immature / total neutrophil ratio, total PMN count, immature PMN count, degenerative changes in PMN and platelet count. Methods: 100 inborn neonates with two or more risk factors for EONS, chosen by sequential sampling method were included in this prospective

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Kassim, N. A., E. L. T. Chung, M. M. Alghirani, et al. "Effects of <i>Brachiaria decumbens</i> leaf meal supplementation on the health, blood biomarkers, and relative telomere length of broiler chickens raised in tropical environments." South African Journal of Animal Science 53, no. 5 (2024): 667–77. http://dx.doi.org/10.4314/sajas.v53i5.06.

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The main goal of this investigation was to determine the effects of Brachiaria decumbens leaf meal on the health performance, blood biomarkers, and relative telomere length of broiler chickens raised in tropical conditions. A total of 300, day-old, male, Ross 308 broilers were divided into six groups and given various feeding regimens based on a completely randomized design model. T1 commercial feed was devoid of antibiotics (negative control) whereas T2 commercial feed was supplemented with 100 mg/kg oxytetracycline (positive control). Commercial diets supplemented with 25, 50, 75, and 100 mg

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Lynch, Susan, David Stirling, and Christopher A. Ludlam. "Microparticles (platelet, Endothelial, and Leucocyte) Are Elevated in Patients with Myeloproliferative Disorders." Blood 110, no. 11 (2007): 1552. http://dx.doi.org/10.1182/blood.v110.11.1552.1552.

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Abstract Patients with myeloproliferative disorders (MPD) have an excess of thrombotic complications which is not fully corrected by normalisation of their elevated haematocrit or thrombocytosis. The mechanisms responsible for this are not completely understood but platelets, leucocytes and endothelial cells have all been implicated. Plasma microparticles are observed to be elevated in other diseases associated with thrombotic complications. We measured platelet (PMP), endothelial (EMP), red cell (RMP) and leucocyte (LMP) microparticles in patients with MPD compared to healthy controls. Microp

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Bhuiyan, Mohammad Monzurul Alam, Md Saiful Islam, Sheuli Ferdousi, et al. "Assesment of Coronary Artery Disease by The Detection of Inflammatory Marker Like Erythrocyte Sedimentation Rate, Neutrophil Lymphocyte Ratio and Leucocyte Count." University Heart Journal 10, no. 2 (2015): 55–59. http://dx.doi.org/10.3329/uhj.v10i2.26121.

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Background: The inflammatory marker like erythrocyte sedimentation rate (ESR), neutrophil lymphocyte ratio (NLR), total leucocyte count can be a useful tool to detect and measure the early detection of coronary artery disease (CAD). Objective: To assess the ESR, NLR and total leucocyte count as a useful inflammatory marker for detection of coronary artery disease (CAD). Methods: This case control study was conducted in the Department of Clinical pathology in collaboration with Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka from March 2014 to Febru

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Husnain Ali, Ejaz Hussain, Imran Mahmood Khan, Iqtada Haider Shirazi, Muhammad Imran, and Bilal Ahmad. "Diagnostic Value of Immature-to-Total Neutrophil Ratio in Neonatal Sepsis." Journal of Islamabad Medical & Dental College 8, no. 4 (2019): 166–70. http://dx.doi.org/10.35787/jimdc.v8i4.475.

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Background: Neonatal sepsis is the third most common reason of neonatal mortality in Pakistan. Blood culture, the gold standard test for diagnosis of neonatal sepsis, is time consuming. Therefore, rapid diagnostic tests with good specificity and sensitivity is needed for accurate and early diagnosis of this condition. The objective of this study was to determine the diagnostic value of abnormal (≥ 0.2) immature-to-total-neutrophil ratio in neonatal sepsis.Material and Methods: This cross-sectional study was carried out on 288 neonates, aged 0-28 days, admitted with suspected sepsis. Detailed h

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Gamal, Yasser, Sarah O. M. Abd ElRaouf, Sherif A. A. Mohamed, and Azza A. Eltayeb. "The hematological parameters in children with scorpion sting." Journal of Current Medical Research and Practice 8, no. 4 (2023): 182–87. http://dx.doi.org/10.4103/jcmrp.jcmrp_55_23.

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Background Scorpion stings are common emergency events in Upper Egypt, with significant morbidity and mortality. We aimed to investigate the hematological parameter and their relation to the severity of envenomation in children presenting with scorpion stings. Methods The current study is an observational hospital-based case-control study that was carried out at the Emergency and Intensive Care Units, from January 2022 to December 2022. The hematological parameters were compared between these cases and those of controls. Results The study included 42 cases and 42 controls. The studied cases an

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Ravi, Kanth Mamidipalli, Thirupathi Rao J., Srinivas B., and Kusuma Gullipalli. "A Study on Clinical, Ultrasound and Laboratory Profile of Dengue Infection in Adults." International Journal of Current Pharmaceutical Review and Research 15, no. 06 (2023): 328–36. https://doi.org/10.5281/zenodo.12591064.

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AbstractIntroduction: Dengue is one of the most rapidly spreading vector-borne viral diseases worldwide and its incidence in India is also on the rise due to increasing urbanization. It hasvariable clinical presentation and can affect all age groups. The disease has a spectrum ofdengue fever, dengue hemorrhagic fever and dengue shock syndrome. The laboratory valuesto be looked for include hematological and serological tests. Aim of the study: To determinethe clinical, ultrasound and laboratory findings in adult patients with dengue infection.Materials and Methods: This was a Retrospective, hos

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Iwuji, C. C., I. Reeves, K. Nambiar, and D. Richardson. "Diagnostic utility of urethral smears in predicting urethral chlamydia in HIV-infected men." International Journal of STD & AIDS 19, no. 11 (2008): 741–43. http://dx.doi.org/10.1258/ijsa.2008.008118.

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We collected data from 218 HIV-infected men to assess the usefulness of the urethral smear and symptoms in predicting Chlamydia trachomatis infection. Prevalence of urethral chlamydia was 9%. A polymorphonuclear leucocyte (PMNL) count ≥5 was 73% sensitive and 71% specific for C. trachomatis infection. Adjusted odds ratio for risk of chlamydial infection was significant for urethral irritation (7.48; 1.54–36.4), a PMNL count of 20 or more (9.83; 2.52–8.4) and a PMNL count of 5–19 (4.10; 1.34–12.5). We had to perform 50 urethral smears in HIV-positive men without symptoms to treat one case of C.

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Adah, Deborah Arimie, Adakole Sylvanus Adah, Charlse Obiora Nwonuma, Boluwaji Olaosebikan, and Taiwo Oyekunle. "Ameliorative effects of ascorbic acid on hematological and water quality parameters following a 100 km transportation of adult Clarias gariepinus." Media Kedokteran Hewan 34, no. 1 (2023): 13–26. http://dx.doi.org/10.20473/mkh.v34i1.2023.13-26.

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Experiments were performed to determine the effects of ascorbic acid on haematological and water quality parameters of Clarias gariepinus subjected to road transportation. A total of 40 apparently healthy adult Clarias gariepinus of an average weight of 450.46 ± 23.06 g and an average length of 38. 23 ± 4.46 cm were used for the experiment and were divided into two groups. Group I (AAF) was administered ascorbic acid daily for one month and on the day of transportation while group II (NAF) was not administered. After transportation of the erythrocyte counts, packed cell volume was significantl

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Adhikari, Bindu, Punam Paudyal, Paricha Upadhyaya, Jyoti Agrawal, and Basudha Khanal. "Use of hematological parameters as an early screening tool for neonatal sepsis." Journal of Pathology of Nepal 11, no. 2 (2021): 1848–53. http://dx.doi.org/10.3126/jpn.v11i2.33781.

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Background: Neonatal sepsis continues to be a major public health problem in developing countries. Due to the nonspecific clinical manifestations of neonatal sepsis, the longer turnaround time for culture reports, an early diagnostic tool is essential for the initiation of appropriate and timely treatment. Materials and Methods: This is a cross-sectional study of 470 clinically suspected cases of neonatal sepsis admitted in the pediatrics department of B.P. Koirala Institute of Health Sciences, Dharan, Nepal. Following hematological parameters: abnormal total leucocyte count, abnormal total po

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Sinduja, Suresh Kumar, and Rajesh Kanna Nandagopal Radha. "Analysing the association of Helicobacter pylori induced gastritis with neutrophil-lymphocyte ratio (NLR) and volume, conductance, scatter characteristics of LH780 Coulter." International Journal of Experimental Research and Review 30 (April 30, 2023): 46–56. http://dx.doi.org/10.52756/ijerr.2023.v30.005.

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Helicobacter (H.) pylori is a bacterium that infects the stomach leading to chronic gastritis. In cases of extreme infection, it can lead to condition of painful sores called peptic ulcers. To determine the association of H. pylori infection in gastric mucosa with blood parameters like Neutrophil-Lymphocyte ratio (NLR) and volume, conductance and scatter (VCS) characteristics were studied using LH780 Coulter haemogram. Blood samples of 100 normal subjects and 100-gastritis cases were collected for testing complete blood count. Biopsies of the gastric tract were also conducted for the 100 gastr

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Nugroho, Irfan Dzakir, Dwi Hidayah, and Harsono Salimo. "Comparison Neutrophil to Lymphocyte Count Ratio with C-Reactive Protein as a Predictor for Neonatal Sepsis." Indonesian Journal of Medicine 6, no. 2 (2021): 135–44. https://doi.org/10.26911/theijmed.v6i2.384.

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Background: Accurate early detection of bacteriemia plays an important role in the treatment and prognosis of infected neonates, but is constrained by the limitations of specific sepsis markers for detecting bacteriemia. NLCR or neutrophil to lymphocyte count ratio in adult population shows a more sensitive parameter in predicting infection and has the advantage of being economical and widely available. The role of NLCR in the neonatal population has not been widely studied. The purpose of this study was to analyze NLCR versus CRP as a predictor of neonatal sepsis.Subjects and Method: This s

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Nugroho, Irfan Dzakir, Dwi Hidayah, and Harsono Salimo. "Comparison Neutrophil to Lymphocyte Count Ratio with C-Reactive Protein as a Predictor for Neonatal Sepsis." Indonesian Journal of Medicine 6, no. 2 (2021): 135–44. https://doi.org/10.26911/theijmed.2021.6.2.384.

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Background: Accurate early detection of bacteriemia plays an important role in the treatment and prognosis of infected neonates, but is constrained by the limitations of specific sepsis markers for detecting bacteriemia. NLCR or neutrophil to lymphocyte count ratio in adult population shows a more sensitive parameter in predicting infection and has the advantage of being economical and widely available. The role of NLCR in the neonatal population has not been widely studied. The purpose of this study was to analyze NLCR versus CRP as a predictor of neonatal sepsis.Subjects and Method: This s

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Saharay, M., D. A. Shields, J. B. Porter, J. H. Scurr, and P. D. Coleridge Smith. "Leucocyte Activity in Volunteers in Response to Experimental Venous Hypertension." Phlebology: The Journal of Venous Disease 12, no. 4 (1997): 122–26. http://dx.doi.org/10.1177/026835559701200402.

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Objective: To investigate leucocyte activation in normal volunteers subjected to short-term venous hypertension by measuring the cell surface expression of the integrin CD11b and the selectin CD62L on neutrophils and monocytes before and after short-term venous hypertension. Plasma levels of L-selectin, which is shed by leucocytes upon activation, were also measured. Design: Prospective study, measuring white cell count, neutrophil and monocyte surface CD11b and L-selectin expression in whole blood using a fluorescent-labelled monoclonal antibody in a flow cytometer, and plasma L-selectin by a

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Wurth, Rachel, Megan Rescigno, Chelsi Flippo, Constantine A. Stratakis, and Christina Tatsi. "Inflammatory biomarkers in the evaluation of pediatric endogenous Cushing syndrome." European Journal of Endocrinology 186, no. 4 (2022): 503–10. http://dx.doi.org/10.1530/eje-21-1199.

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Objective Inflammatory biomarkers, such as absolute neutrophil and lymphocyte counts, neutrophil-to-lymphocyte ratio (NLR), platelet (PLT)-to-lymphocyte ratio (PLR) and monocyte-to-lymphocyte ratio (MLR), are associated with the progression and development of several disorders. Although patients with Cushing syndrome (CS) have immunosuppression with altered leucocyte counts, the profile of the inflammatory biomarkers in these patients has not been extensively studied. Design We compared a panel of inflammatory biomarkers in patients with active endogenous CS (n of complete blood count (CBC) re

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Yanchev, Ivan, Nikola Metodiev, Penka Moneva, and Maya Ignatova. "Seasonal changes of some biochemical indicators in four sheep herds from Bulgarian Dairy Synthetic Population." Bulgarian Journal of Animal Husbandry 62, no. 1 (2025): 27–37. https://doi.org/10.61308/dcyh5841.

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The purpose of the present study was to evaluate seasonal differences in the values of some enzymes and metabolites - ALT, AST, ALP, serum iron, glucose, as well as WBC count and N/L ratio in four herds of sheep from the Bulgarian Dairy Synthetic Population (BDSP), raised at different altitudes. The research was conducted in sheep farms of the Sofia region - Ravnishte (391 m a.s.l.), IAS - Kostinbrod (548 m a.s.l.), Mirkovo (715 m a.s.l.) and Bosnek (940 m a.s.l.). Blood samples were taken from selected 24 animals from each sheep herd. Analysis of biochemical parameters was performed in extrac

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Singgih, Venny, Ketut Suryana, Ida Ayu Jasminarti Dwi Kusumawardani, Ni Wayan Candrawati, I. Gede Ketut Sajinadiyasa, and Ida Bagus Ngurah Rai. "Role of pleural fluid interleukin-6, neutrophil-lymphocyte ratio, and monocyte-lymphocyte ratio in distinguishing tuberculous and malignant pleural effusions." International Journal of Advances in Medicine 8, no. 4 (2021): 492. http://dx.doi.org/10.18203/2349-3933.ijam20211046.

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Background: Pleural effusion is caused by various disease, including tuberculosis infection and malignancy. To determine the etiology, immunologic parameters are needed to distinguish tuberculous and malignant pleural effusions, including pleural fluid interleukin-6 (IL-6), neutrophil-lymphocyte ratio (NLR), and monocyte-lymphocyte ratio (MLR).Methods: This was a cross-sectional study, conducted at Sanglah General Hospital in Denpasar from March 2020 to September 2020. Pleural fluid IL-6 and leucocyte differential count were measured from subjects with tuberculous and malignant pleural effusio

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