Academic literature on the topic 'Leukocyte Immunoglobulin-Like Receptor B1'

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Journal articles on the topic "Leukocyte Immunoglobulin-Like Receptor B1"

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Chan, K. R., E. Z. Ong, H. C. Tan, et al. "Leukocyte immunoglobulin-like receptor B1 is critical for antibody-dependent dengue." Proceedings of the National Academy of Sciences 111, no. 7 (2014): 2722–27. http://dx.doi.org/10.1073/pnas.1317454111.

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Lebedin, Mikhail, and Kathrin de la Rosa. "Diversification of Antibodies: From V(D)J Recombination to Somatic Exon Shuffling." Annual Review of Cell and Developmental Biology 40, no. 1 (2024): 265–81. http://dx.doi.org/10.1146/annurev-cellbio-112122-030835.

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Antibodies that gain specificity by a large insert encoding for an extra domain were described for the first time in 2016. In malaria-exposed individuals, an exon deriving from the leukocyte-associated immunoglobulin-like 1 (LAIR1) gene integrated via a copy-and-paste insertion into the immunoglobulin heavy chain encoding region. A few years later, a second example was identified, namely a dual exon integration from the leukocyte immunoglobulin-like receptor B1 (LILRB1) gene that is located in close proximity to LAIR1. A dedicated high-throughput characterization of chimeric immunoglobulin hea
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Rafiei, Anahita, Marco Gualandi, Chia-Lung Yang, et al. "IOS-1002, a Stabilized HLA-B57 Open Format, Exerts Potent Anti-Tumor Activity." Cancers 16, no. 16 (2024): 2902. http://dx.doi.org/10.3390/cancers16162902.

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HLA-B27 and HLA-B57 are associated with autoimmunity and long-term viral control and protection against HIV and HCV infection; however, their role in cancer immunity remains unknown. HLA class I molecules interact with innate checkpoint receptors of the LILRA, LILRB and KIR families present in diverse sets of immune cells. Here, we demonstrate that an open format (peptide free conformation) and expression- and stability-optimized HLA-B57-B2m-IgG4_Fc fusion protein (IOS-1002) binds to human leukocyte immunoglobulin-like receptor B1 and B2 (LILRB1 and LILRB2) and to killer immunoglobulin-like re
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Huang, Luofei, Han Li, and Quanzhi Lin. "Identification of key genes and diagnostic biomarkers for peripheral atherosclerosis: A multi-omics approach." Medicine 104, no. 21 (2025): e42437. https://doi.org/10.1097/md.0000000000042437.

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Peripheral atherosclerosis (PAS), characterized by lipid plaque accumulation in arterial walls, significantly increases cardiovascular risk. This study aimed to identify molecular biomarkers and elucidate underlying mechanisms of PAS progression. We analyzed 2 gene expression omnibus datasets (GSE28829, GSE100927) to identify differentially expressed genes (P < .05, |log2FC| ≥ 0.585). Functional enrichment (Gene Ontology/Kyoto Encyclopedia of Genes and Genomes) and Mendelian randomization analyses were performed using genome-wide association study and expression quantitative trait loci data
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Cadena-Mota, Sandra, Adriana Monsiváis-Urenda, Mariana Salgado-Bustamante, et al. "Effect of cytomegalovirus infection and leukocyte immunoglobulin like receptor B1 polymorphisms on receptor expression in peripheral blood mononuclear cells." Microbiology and Immunology 62, no. 12 (2018): 755–62. http://dx.doi.org/10.1111/1348-0421.12661.

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Truong, Anh Duc, Yeojin Hong, Janggeun Lee, et al. "Chicken novel leukocyte immunoglobulin-like receptor subfamilies B1 and B3 are transcriptional regulators of major histocompatibility complex class I genes and signaling pathways." Asian-Australasian Journal of Animal Sciences 32, no. 5 (2019): 614–28. http://dx.doi.org/10.5713/ajas.18.0561.

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Kuroki, Kimiko, Sayoko Kobayashi, Mitsunori Shiroishi, et al. "Detection of weak ligand interactions of leukocyte Ig-like receptor B1 by fluorescence correlation spectroscopy." Journal of Immunological Methods 320, no. 1-2 (2007): 172–76. http://dx.doi.org/10.1016/j.jim.2006.11.009.

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Shiroishi, Mitsunori, Kimiko Kuroki, Kouhei Tsumoto, et al. "Entropically Driven MHC Class I Recognition by Human Inhibitory Receptor Leukocyte Ig-like Receptor B1 (LILRB1/ILT2/CD85j)." Journal of Molecular Biology 355, no. 2 (2006): 237–48. http://dx.doi.org/10.1016/j.jmb.2005.10.057.

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Ryan, D., S. Kossover, S. Mitchell, C. Frantz, L. Hennessy, and H. Cohen. "Subpopulations of common acute lymphoblastic leukemia antigen-positive lymphoid cells in normal bone marrow identified by hematopoietic differentiation antigens." Blood 68, no. 2 (1986): 417–25. http://dx.doi.org/10.1182/blood.v68.2.417.417.

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Abstract Bone marrow samples from normal adults and children with nonhematologic malignancies not involving the marrow, acute lymphoblastic leukemia (ALL) in continued remission, and immune cytopenias were studied by two- color immunofluorescence (IF) and flow cytometry to characterize common acute lymphoblastic leukemia antigen (CALLA)-positive marrow lymphoid cells. Marrow was separated by Ficoll/Hypaque centrifugation followed by passage over a monoclonal antibody affinity column to remove myeloid cells prior to IF staining. A higher proportion of CALLA-positive cells was found in the pedia
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Ryan, D., S. Kossover, S. Mitchell, C. Frantz, L. Hennessy, and H. Cohen. "Subpopulations of common acute lymphoblastic leukemia antigen-positive lymphoid cells in normal bone marrow identified by hematopoietic differentiation antigens." Blood 68, no. 2 (1986): 417–25. http://dx.doi.org/10.1182/blood.v68.2.417.bloodjournal682417.

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Bone marrow samples from normal adults and children with nonhematologic malignancies not involving the marrow, acute lymphoblastic leukemia (ALL) in continued remission, and immune cytopenias were studied by two- color immunofluorescence (IF) and flow cytometry to characterize common acute lymphoblastic leukemia antigen (CALLA)-positive marrow lymphoid cells. Marrow was separated by Ficoll/Hypaque centrifugation followed by passage over a monoclonal antibody affinity column to remove myeloid cells prior to IF staining. A higher proportion of CALLA-positive cells was found in the pediatric marr
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Dissertations / Theses on the topic "Leukocyte Immunoglobulin-Like Receptor B1"

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Kalogeropoulos, Michail. "Novel mechanisms of dendritic cell regulation by leukocyte immunoglobulin-like receptor B1." Thesis, University of Aberdeen, 2014. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=210082.

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Dendritic cells play an essential role in activating immune responses upon recognition of pathogens. This results in maturation and migration to the lymph nodes, where T cells are stimulated by upregulated antigen presentation, co-stimulation and cytokine secretion. DCs are also considered important in inhibiting inappropriate immune responses against self-peptides which could lead to the development of autoimmunity. This has been attributed to DCs that demonstrate inhibited co-stimulation and cytokine secretion. It has been previously shown that the continuous ligation of an immunomodulatory
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Dumont, Clément. "Importance des lymphocytes T effecteurs exprimant ILT2 dans les cancers urologiques traités par immunothérapie." Electronic Thesis or Diss., Université Paris Cité, 2024. http://www.theses.fr/2024UNIP5267.

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L'immunothérapie par inhibiteurs des points de contrôle immunitaires (ICI) fonctionne à travers l'expansion de lymphocytes T CD8+ effecteurs antitumoraux à partir de précurseurs "exhausted" exprimant le récepteur inhibiteur PD-1. Elle est désormais incontournable dans le traitement des carcinomes rénaux à cellules claires (CRcc) et urothéliaux (CU). Nous avons préalablement démontré que le microenvironnement tumoral du CRcc chez l'homme comprend une populations de lymphocytes T CD8+ effecteurs exprimant le récepteur inhibiteur ILT2 (LILRB1) mais pas PD-1, hautement cytotoxiques mais pouvant êt
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Ichise, Hiroshi. "NK cell alloreactivity against KIR-ligand-mismatched HLA-haploidentical tissue derived from HLA haplotype-homozygous iPSCs." Kyoto University, 2017. http://hdl.handle.net/2433/228232.

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Silva, Pamela Portela da. "Análise de polimorfismos dos genes KIR e HLA classe I em pacientes com câncer colorretal." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2016. http://hdl.handle.net/10183/148088.

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O câncer colorretal (CCR) pode ocorrer em qualquer parte do cólon ou do reto e representa o terceiro câncer mais comum no mundo em ambos os sexos. As células Natural Killer (NK) fazem parte do sistema imune inato reconhecendo moléculas de HLA de classe I em células alvo, através de seus receptores de membrana killer cell immunoglobulin-like receptors (KIR). O objetivo deste estudo foi avaliar a associação entre os genes KIR e os ligantes HLA em pacientes com câncer colorretal e controles saudáveis. Examinamos o polimorfismo de 16 genes KIR e seus ligantes HLA em 154 pacientes caucasóides com C
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Silva, Pamela Portela da. "Estudo de polimorfismos dos genes KIR e HLA em pacientes com câncer de próstata." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2011. http://hdl.handle.net/10183/35890.

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O câncer de próstata é o segundo câncer mais comum entre homens, uma vez que tanto a incidência como a mortalidade aumentam exponencialmente após a idade de 50 anos. As células Natural Killer (NK) fazem parte do sistema imune inato e reconhecem moléculas de HLA de classe I na célula alvo, através de seus receptores de membrana, chamados killer immunoglobulin-like-receptors (KIR). O objetivo desse estudo foi avaliar a associação entre os genes KIR e HLA em pacientes com câncer de próstata e grupo controle. Genotipamos 200 pacientes com diagnóstico de câncer de próstata e 185 pacientes saudáveis
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Jobim, Maria Regina Sampaio Leite. "Estudo do polimorfismo dos genes KIR e HLA em pacientes com câncer de mama e grupo controle." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2014. http://hdl.handle.net/10183/97026.

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O presente estudo tem como objetivo investigar a frequência dos diversos polimorfismos dos genes KIR (Killer Immunoglobulin-like Receptors) e HLA C1 e C2 em um grupo de pacientes com câncer de mama e comparar com um grupo controle de indivíduos sadios. As células natural killer (NK) são linfócitos que diferem das células T e B e que fazem parte da imunidade natural, reconhecendo as moléculas HLA (Antígenos Leucocitários Humano) de classe I em células infectadas por vírus ou em células tumorais, através de seus receptores de membrana. Os principais receptores das células NK são conhecidos como
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Book chapters on the topic "Leukocyte Immunoglobulin-Like Receptor B1"

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Hirayasu, Kouyuki, and Hisashi Arase. "Leukocyte Immunoglobulin-Like Receptor (LILR)." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_101689.

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Hirayasu, Kouyuki, and Hisashi Arase. "Leukocyte Immunoglobulin-Like Receptor (LILR)." In Encyclopedia of Signaling Molecules. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_101689-1.

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Wende, Hagen, Andreas Ziegler, and Armin Volz. "Genomic organization of the ILT11 gene, a novel member of the Leukocyte Receptor Cluster (LRC)." In Activating and Inhibitory Immunoglobulin-like Receptors. Springer Japan, 2001. http://dx.doi.org/10.1007/978-4-431-53940-7_3.

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"Leukocyte Immunoglobulin Like Receptor B1 (LILRB1)." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_102052.

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"Leukocyte Immunoglobulin Like Receptor B2 (LILRB2)." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_102053.

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"Leukocyte Immunoglobulin Like Receptor B3 (LILRB3)." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_102054.

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"Leukocyte Immunoglobulin Like Receptor B4 (LILRB4)." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_102055.

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"Leukocyte Immunoglobulin Like Receptor B5 (LILRB5)." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_102056.

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Conference papers on the topic "Leukocyte Immunoglobulin-Like Receptor B1"

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Mitsune, A., M. Yamada, N. Fujino, et al. "Upregulation of Leukocyte Immunoglobulin-Like Receptor B4 on Interstitial Macrophages in COPD." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4042.

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Guo, Jianping, Yuxuan Wang, and Yundi Tang. "238 Leukocyte immunoglobulin-like receptor A3 (LILRA3) promotes lupus-like disease in a murine lupus model." In 13th International Congress on Systemic Lupus Erythematosus (LUPUS 2019), San Francisco, California, USA, April 5–8, 2019, Abstract Presentations. Lupus Foundation of America, 2019. http://dx.doi.org/10.1136/lupus-2019-lsm.238.

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Tang, Yundi, Chen Chen, and Jianping Guo. "LP-093 Role of leukocyte immunoglobulin-like receptor a3 (LILRA3) in the pathogenesis of lupus-like disease." In The 15th International Congress on Systemic Lupus Erythematosus and The 43rd KCR Annual Scientific Meeting & 17th International Symposium (LUPUS & KCR 2023). Lupus Foundation of America, 2023. http://dx.doi.org/10.1136/lupus-2023-kcr.197.

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Sen, Shiraj, Andrae L. Vandross, David Sommerhalder, et al. "1464 Phase 1 results of OR502, an antibody against leukocyte immunoglobulin-like receptor B2 (LILRB2), in patients with advanced cancers." In SITC 39th Annual Meeting (SITC 2024) Late Breaking Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/jitc-2024-sitc2024.1464.

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Zhang, W., Z. Sun, N. Kimura, W. Wang, C. Wei, and M. Kraft. "The Genetic Polymorphisms in Leukocyte Immunoglobulin-like Receptor B3 (LILRB3) Gene Are Associated With the Respiratory Diseases in the Population With African American Ancestry." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a3020.

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Sen, Shiraj, Andrae L. Vandross, David Sommerhalder, et al. "680 Adaptive design elements in a Ph 1–2 study of OR502, a novel antibody against leukocyte immunoglobulin-like receptor B2 (LILRB2), in response to evolving Ph 1 data and changing regulatory environment." In SITC 39th Annual Meeting (SITC 2024) Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/jitc-2024-sitc2024.0680.

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