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Dissertations / Theses on the topic 'Leysin'

Author: Grafiati

Published: 27 February 2023

Last updated: 31 July 2025

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1

Chang, Chang Viviana Lyda. "Tumor de células de Leydig en caninos." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2013. https://hdl.handle.net/20.500.12672/14461.

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Publicación a texto completo no autorizada por el autor<br>El documento digital no refiere asesor<br>Pretende brindar información actualizada del Tumor de Células de Leydig así como medidas de tratamiento y pronóstico. Un factor de riesgo para la presentación de neoplasias en este órgano es el criptorquidismo para el caso de Seminoma y Tumor de Células de Sertoli, pero no para el Tumor de Células de Leydig, a excepción del gato y del caballo donde sí parece estar asociado al criptorquidismo. El tumor de células de Leydig es una neoplasia testicular generalmente benigna, cuya causa es desconoc

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2

Lefèvre, Anick. "De la fonction des cellules de Leydig." Lyon 1, 1992. http://www.theses.fr/1992LYO10008.

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Afin d'etudier la fonction des cellules de leydig et sa regulation nous avons construit, par hybridation intraspecifique et intra-tissulaire, une lignee exprimant la steroidogenese dans son entier. Nous avons au prealable mis au point une technique de purification des cellules de leydig etabli des cultures primaires de ces cellules et defini les parametres permettant l'expression de leur fonction in vitro valide un nouveau mode de fusion par champ electrique. La lignee k9 obtenue exprime une steroidogenese complete elle est a ce jour la seule capable de transcrire le gene codant pour le cytoch

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3

Gamboa, Acuña Brenda Adriana, Zambranoa Rayza Guillén, and Mendozaa Grecia Lizzetti. "Tumor de Leydig simulando una neoplasia germinal." Elsevier B.V, 2016. http://hdl.handle.net/10757/614830.

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Main findings A case is presented of a Leydig cell neoplasm in a 25 year-old male patient with no classic risk factors with an atypical outcome. The tumour mass was histologically analysed and was found to have features compatible with a germ cell neoplasm. A right orchiectomy was performed, followed by chemotherapy. After treatment, pulmonary metastasis, lymph nodes, and peri-hepatic hydronephrosis were found. The patient died two months after his last hospital admission. Case hypothesis Leydig cell tumours account for 1% to 3% of all testicular tumours. They occur at any age, especi

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4

Limoges, Mireille. "Apoptosis in primary cultures of rat Leydig cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ36586.pdf.

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5

Renlund, Nina. "Hormonal and paracrine influences on Leydig cell steroidogenesis /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-842-8/.

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6

Kilcoyne, Karen. "Early life programming of adult Leydig cell function." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/9533.

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There is increasing evidence to suggest that fetal events can predetermine reproductive health and general wellbeing in adulthood, a process termed 'fetal programming'. This refers to the association between altered fetal growth/development and health disorders in adulthood e.g. the metabolic syndrome, which is linked to low male testosterone levels. Studies from both Europe and the USA have shown that adult male testosterone levels have been declining, independent of age. As low testosterone levels in aging men are associated with increased morbidity and mortality, this highlights the importa

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7

Martin, Mary Clare Hewlett. "Children and religion in Walthamstow and Leyton, 1740-1870." Thesis, Goldsmiths College (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312087.

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8

Monks, Lara Kay. "The structure/function relationships of the murine Leydig tumour." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300248.

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9

Tsai, Yi-Ting. "Testicular macrophage regulation of Leydig cell development and function." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/25853.

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The unique microenvironment structure of the testis affects the function of Leydig Cells (LCs) both physically and physiologically. The testicular macrophages are located adjacent to the LCs in the interstitial space and the two cell types share a close physiological and functional relationship. Macrophages first appear in the testis in prenatal life, and increase in number during both prenatal and postnatal development when they support the development and function of the testis. The dynamics of macrophage population expansion correlates with generation of the adult Leydig cell population in

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10

Hussein, Mohamed Osman. "Hormonal modulation of Leydig cell membrane luteinizing hormone receptors /." The Ohio State University, 1986. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487267024995937.

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11

Qureshi, Safia Judith. "Regulation of human Leydig cells : comparison with the rat." Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/20130.

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The major aim of this thesis was to study the regulation of testosterone production in the human testis. The technique used to isolate human Leydig cells was improved, so that Leydig cells responsive to hCG were obtained consistenly in large yields. There was marked subject variation in both the basal levels of testosterone produced and in the responsiveness of the cells to hCG. Sertoli cells are believed to modulate Leydig cell function via the action of secreted factors. The nature of these factors is not known, although in the rat GnRH and AVP are potential candidates. Basal testosterone pr

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12

Patel, Saloni Hiten. "Inducible gene targeting in the male : tamoxifen adversely impacts postnatal testicular development and function." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/25870.

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Normal development and function of the male reproductive tract relies on the crucial balance between androgen and estrogen signalling, furthermore estrogens play an important role in the regulation of spermatogenesis and steroidogenesis. Tamoxifen (TAM) inducible Cre-loxP systems are widely used to study testicular function. TAM is a selective estrogen receptor modulator (SERM), thereby exerting anti- and pro-estrogenic effects. Therefore, it was hypothesised that acute (single dose) TAM administration to the postnatal testis has significant long-term effects on testicular development and adul

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13

REMY, DOMINIQUE. "Tumeurs testiculaires a cellules de leydig : a propos de quatre observations et revue de la litterature." Amiens, 1989. http://www.theses.fr/1989AMIEM065.

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14

Doepner, Richard Fritz Georg. "Molekulare Effekte von GABA in adulten - und TM3 Leydig-Zellen." Diss., lmu, 2006. http://nbn-resolving.de/urn:nbn:de:bvb:19-54834.

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15

Supornsilchai, Vichit. "Effects of endocrine disruptors on adrenocortical and leydig cell steroidogenesis /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-276-7/.

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16

RACINE, CHRYSTELE. "La cellule de leydig : cellule cible de l'hormone anti-mullerienne." Paris 7, 1999. http://www.theses.fr/1999PA077210.

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L'hormone anti-mullerienne (amh) est une glycoproteine de 140 kd synthetisee par les cellules de sertoli immatures et par les cellules de la granulosa apres la naissance. Son role principal est de faire regresser les canaux de muller. L'amh s'apparente par son domaine carboxy-terminal a la famille du tgf- (30% d'homologie). Son signal est transmis via un recepteur de type i, inconnu, et un recepteur de type ii, deja clone. Le but de mon travail a ete de caracteriser une nouvelle cible de l'amh, d'utilisation pratique, afin d'identifier le recepteur de type i de l'amh. Nous avons tout d'abord m

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17

Garcia, Patrick Vianna 1978. "Analise histologica e estereologica do epididimo e celulas deLeydig em camundongos submetidos ao criptorquidismo experimental e orquidopexia." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317695.

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Orientadores: Luis Antonio Violin Pereira, Suzana de Fatima Paccola Mesquita<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-06T21:14:15Z (GMT). No. of bitstreams: 1 Garcia_PatrickVianna_M.pdf: 2397318 bytes, checksum: 8b518ea012a3a11e92ce5775536bee0f (MD5) Previous issue date: 2006<br>Resumo: O epidídimo de mamíferos, através da secreção de proteínas andrógeno-dependentes, é responsável pela maturação dos espermatozóides visando o processo de fecundação, alterando-os em características morfológicas e bioquímicas. O

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18

Giner, Xavier. "Caractérisation du promoteur Insl3 de souris dans les cellules de leydig." Thesis, Université Laval, 2009. http://www.theses.ulaval.ca/2009/26557/26557.pdf.

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19

Weißer, Judith. "Steroidogenesis and steroidogenic gene expression in postnatal fetal rat Leydig cells." Doctoral thesis, Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-146856.

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Die vorliegende Arbeit untersucht die Steroidogenese und die Expression Leydig-Zellspezifischer Gene in Kulturen postnataler fetaler Leydig-Zellen (PFLC). Die Stimulation von PFLC mit hCG und (Bu)2cAMP bewirkt eine Steigerung der Testosteronproduktion in vitro. Es wurde eine zeitabhängige Abschwächung der Testosteronproduktion durch (Bu)2cAMPstimulierte PFLC beobachtet. Diese war begleitet von einer Akkumulation von Progesteron im Kulturmedium und einer Suppression der Expression von P450c17 auf dem translatorischen Level. Während der Kultivierung verloren PFLC ihre Fähigkeit der Expression Le

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20

Allan, Murray Masson. "Hydrothermal processes in the Mount Leyshon Intrusive Complex, Australia : microanalytical insights." Thesis, University of Leeds, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427766.

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21

Kristina, Pogrmić. "Mehanizmi delovanja atrazina na steroidogenu aktivnost Leydig-ovih ćelija peripubertalnih pacova." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2010. http://dx.doi.org/10.2298/NS20100408POGRMIC.

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Rezultati prikazani u ovom radu opisuju efekte in vivo primene atrazina (2-hloro-4-etilamino-6-izopropilamino-s-triazin) na ex vivo steroidogenezu u Leydig-ovim ćelijamaperipubertalnih pacova (tretiranih sa 50 mg/kg i 200 mg/kg telesne mase od 23. do 50.dana starosti). Dobijeni rezultati jasno ukazuju da 28-dnevna in vivo primena atrazinasnažno inhibira testikularnu steroidogenezu, smanjujući ekspresiju gena za steroidogeneenzime i druge regulatorne proteine uključene u kontrolu testikularne steroidogeneze uLeydig-ovim ćelijama peripubertalnih pacova. Rezultati in vivo primene atrazinapokazuju

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22

Coonce, Mary M. "Consequences of Premature and Persistent Luteinizing Hormone Receptor Activation on Leydig Cell Development." Available to subscribers only, 2009. http://proquest.umi.com/pqdweb?did=1885442061&sid=2&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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23

Bruno, Carlos Eduardo Malavasi. "Desenvolvimento embrionário dos órgãos linfoides do Tubarão-azul, Prionace glauca (Linnaeus, 1758), Elasmobranchii, Carcharhiniformes." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/10/10132/tde-21032017-150059/.

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O tubarão-azul, Prionace glauca (Linnaeus, 1758) é uma espécie cosmopolita, de alto valor comercial, principalmente capturado por embarcações que operam em alto mar e vendido em mercados e feiras-livres. Poucos dados biológicos estão disponíveis sobre esta espécie, principalmente quanto à sua sanidade e, o conhecimento do desenvolvimento de seus órgãos linfoides pode trazer importantes informações neste contexto. Desta forma, o objetivo do trabalho é descrever o desenvolvimento embrionário dos órgãos linfoides em embriões de tubarão-azul: timo, órgão epigonal, baço e órgão de Leydig, quanto à

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24

Colón, Eugenia. "Autocrine and paracrine regulation of Leydig cell survival in the postnatal testis /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-275-0/.

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25

Tremblay, Maxime. "Rôles de KLF6 dans l'expression de INSL3 dans la cellule de LEYDIG." Thesis, Université Laval, 2010. http://www.theses.ulaval.ca/2010/27078/27078.pdf.

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26

Choi, Michael Shui Kuen. "The involvement of calcium and chloride ions in rat Leydig cell steroidgenesis." Thesis, University College London (University of London), 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244247.

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27

Neves, Bruno Vinicius Duarte. "Alterações numéricas e volumétricas das células de Leydig no envelhecimento de ratos." reponame:Repositório Institucional da UFPR, 2017. http://hdl.handle.net/1884/53498.

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Orientador: Prof. Dr. Rogério de Fraga<br>Coorientador: Prof. Dr. Fernando Lorenzini<br>Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências da Saúde, Programa de Pós-Graduação em Clínica Cirúrgica. Defesa: Curitiba, 17/07/2017<br>Referências: p. 47-49<br>Resumo: Introdução: As células de Leydig são responsáveis pela produção de testosterona e sofrem os efeitos deletérios do envelhecimento. Com o avançar da idade, ocorre uma diminuição na esteroidogênese por alterações celulares ainda pouco conhecidas. Objetivos: Analisar os efeitos do envelhecimento nos ratos sobre o vol

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28

de, Albuquerque Couto Janaína. "Avaliação da atividade esteroidogênica testicular de derivados tiazolidinônicos potencialmente hipoglicemiantes." Universidade Federal de Pernambuco, 2011. https://repositorio.ufpe.br/handle/123456789/2206.

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Made available in DSpace on 2014-06-12T15:55:26Z (GMT). No. of bitstreams: 2 arquivo6486_1.pdf: 5259085 bytes, checksum: 0455f27ed957ea8d402554cbef2e71be (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2011<br>Os efeitos do tratamento crônico com tiazolidinonas sobre a esteroidogênese testicular foram avaliados, em virtude dos efeitos relacionados à deficiência androgênica. A fim de contribuir com a concepção de fármacos mais seguros, avaliamos o efeito do tratamento crônico com tiazolidinonas sobre os níveis plasmáticos de testosterona e

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29

OLIVEIRA, Regina Acacia Campos. "Memória em cinética de canais para potáasio ativados por cálcio em células de Leydig." Universidade Federal de Pernambuco, 2003. https://repositorio.ufpe.br/handle/123456789/5009.

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Made available in DSpace on 2014-06-12T17:35:22Z (GMT). No. of bitstreams: 2 arquivo4434_1.pdf: 1195233 bytes, checksum: 867173a6365d8bbee6de86e619be8231 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2003<br>Canais iônicos são proteínas que se encontram nas membranas biológicas. Essas estruturas protéicas podem assumir diferentes estados conformacionais, abertos e fechados, fenômeno este denominado de cinética de canais iônicos. A cinética das transições de um estado para o outro depende da barreira de energia potencial que separa os

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Pinto-Fochi, Maria Etelvina. "Desenvolvimento testicular no gerbilo da Mongolia : diferenciação pos-natal das celulas germinativas e de Leydig." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317891.

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Orientador: Rejane Maira Goes<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-14T18:19:29Z (GMT). No. of bitstreams: 1 Pinto_MariaEtelvina_D.pdf: 7979906 bytes, checksum: 0558bfd8fbc931f0f8dfcc8ad0957763 (MD5) Previous issue date: 2009<br>Resumo: O gerbilo da Mongólia (Meriones unguiculatus) tem sido utilizado de maneira crescente em estudos sobre o sistema genital masculino. Alguns aspectos da espermatogênese e o ciclo do epitélio seminífero dessa espécie são conhecidos, mas investigações sobre o desenvolvimento pós-natal

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31

Murphy, Lyn Irene. "The effects of increased ambient temperature and androgen insensitivity on Leydig cell function." Thesis, Royal Veterinary College (University of London), 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.522696.

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32

Bartlett, Johnathan Mark Seaverns. "Paracrine regulation of the rat testis : studies on seminiferous tubule-Leydig cell communication." Thesis, University of Edinburgh, 1985. http://hdl.handle.net/1842/19174.

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Lima, Thania Rios Rossi. "Células germinativas e células de Leydig em modelo de dano testicular no rato." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/153217.

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Submitted by Thania Rios Rossi Lima null (thania.lima49@gmail.com) on 2018-03-23T01:44:07Z No. of bitstreams: 1 Dissertação Ms. Thania_21.03.2018 - FINAL.pdf: 2338346 bytes, checksum: 1a021d8170dc5458c5963409fd3e1384 (MD5)<br>Approved for entry into archive by Luciana Pizzani null (luciana@btu.unesp.br) on 2018-03-26T16:57:50Z (GMT) No. of bitstreams: 1 lima_trr_me_bot.pdf: 2260557 bytes, checksum: fe4f1058d32d837dd267cda79b2f5f46 (MD5)<br>Made available in DSpace on 2018-03-26T16:57:50Z (GMT). No. of bitstreams: 1 lima_trr_me_bot.pdf: 2260557 bytes, checksum: fe4f1058d32d837dd267cda79b2f5

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Genissel, Christelle. "Regulation de l'expression de l'aromatase dans les cellules de leydig de rat mature." Caen, 2000. http://www.theses.fr/2000CAEN2051.

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Le cytochrome p450 aromatase est l'enzyme responsable de la conversion irreversible des androgenes en estrogenes ; sa presence dans les cellules testiculaires des mammiferes est bien etablie. L'etude de differents modulateurs (androgenes, gonadotrophines et certains facteurs paracrines) sur l'activite aromatase testiculaire a suscite de nombreux travaux. Cependant, la regulation de l'expression du gene de l'aromatase, en particulier dans les cellules de leydig n'a pas ete rapportee. En utilisant une technique de rt-pcr quantitative competitive, nous avons mesure apres 24 heures de culture les

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35

Li, Lei. "The regulation of stanniocalcin-1 gene expression in rat sertoli and leydig cells." HKBU Institutional Repository, 2006. http://repository.hkbu.edu.hk/etd_ra/784.

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36

Goncalves, Renata. "Interactions entre la signalisation estrogénique et la vitamine D dans les cellules testiculaires." Thesis, Normandie, 2018. http://www.theses.fr/2018NORMC411/document.

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La 1α,25(OH)2 vitamine D3 (1,25-D3) est synthétisée à partir du cholestérol par l'exposition solaire de la peau. Les effets de cette hormone sont médiées par le récepteur de la vitamine D (VDR) dans le noyau et à la membrane plasmique, et avec le récepteur PDIA3 ils médient des effets génomiques et non-génomique. La vitamine D joue un rôle important dans la reproduction, puisque la réduction de la fertilité a été observée chez les rats déficients en vitamine D. L'estradiol (E2) est synthétisé à partir de la testostérone par l'enzyme aromatase (CYP19). L’E2 a des effets génomiques et non génomi

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Wang, Xiaofei. "The binding property and function of melatonin receptor in peripheral tissues-chick embryonic vessels and young rat leydig cells." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23426172.

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Tyre, Madeline. "Répression de l'expression du gène Insl3 par les estrogènes dans les cellules de Leydig." Thesis, Université Laval, 2013. http://www.theses.ulaval.ca/2013/29813/29813.pdf.

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L’hormone peptidique Insulin-like 3 (INSL3) est produite par les cellules de Leydig du testicule. Elle est essentielle à la première phase de la descente testiculaire lors du développement fœtal. Les divers modèles animaux invalidés en Insl3 présentent une descente testiculaire incomplète chez les mâles, la cryptorchidie. Il s’agit du trouble développemental le plus courant chez les garçons nouveau nés des pays industrialisés et son incidence s’est accrue au cours des dernières décennies. Plusieurs études animales indiquent que les estrogènes répriment l’expression d’Insl3. La répression de l

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39

Martin, Luc. "Implication du récepteur nucléaire NUR77 dans la stéroïdogenèse au niveau des cellules de Leydig." Thesis, Université Laval, 2008. http://www.theses.ulaval.ca/2008/25873/25873.pdf.

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40

Edwards, Gillian. "Some studies of Leydig cell cytotoxicity ethane-1,2-dimethane sulphonate in the male rat." Thesis, University of Manchester, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328323.

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Kukucka, Mark A. "Mechanisms by which hypoxia augments Leydig cell viability and differentiated cell function in vitro." Diss., Virginia Tech, 1993. http://hdl.handle.net/10919/38407.

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The 1980's heralded the discovery and identification of extra-pituitary sources of the neurohypophysial hormone oxytocin in non-neural tissues of several animal species. The presence, location and biosynthesis of significant amounts of oxytocin in the ovarian corpus luteum was followed by the immunocytochemical demonstration of an oxytocin-like peptide in the testicular interstitial cells. Leydig cells, which comprise up to 80% of the testicular intertubular cell population, are known to synthesize testosterone in situ. Indirect evidence indicated that an oxytocin-like peptide was also present

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42

ISHAQ, Muhammad. "Expression of GnRH receptor during functional maturation of pituitary gonadotropes and testicular Leydig cells." Paris 11, 2010. http://www.theses.fr/2010PA11T078.

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43

Afane, Mustapha. "Influence eventuelle des macrophages sur le fonctionnement des cellules de leydig chez le rat." Clermont-Ferrand 2, 1987. http://www.theses.fr/1987CLF2S888.

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Etude du fonctionnement de la cellule de leydig sous l'influence des macrophages peritoneaux ou testiculaires sur la steroidogenese leydigienne. Caracterisation des macrophages du tissu interstitiel testiculaire de rats

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Martin, Luc J. "Implication du récepteur nucléaire NUR77 dans la stéroïdogenèse au niveau des cellules de Leydig." Doctoral thesis, Université Laval, 2008. http://hdl.handle.net/20.500.11794/20397.

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L'enzynle HSD3B2 humaine et la protéine STAR de souris encodées par les gènes HSD3B2 et Star, respectivement, sont retrouvées principalement au niveau des gonades et surrénales. L'importance de STAR comme transporteur du cholestérol et de HSD3B2 comme enzyme de la stéroïdogenèse est lnise en évidence par des mutations de ces gènes causant une hyperplasie congénitale des surrénales, un pseudohermaphrodisme mâle et une insuffisance des surrénales. Un rôle pour la famille de récepteurs nucléaires orphelins NUR 77 dans la stéroïdogenèse a été considéré. En effet, NUR77 est présent dans les gonades

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Pearce, Keenau Mark. "The effect of cissampelos capensis extract on prostate cancer, sertoli and leydig cell function." University of the Western Cape, 2014. http://hdl.handle.net/11394/4307.

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Magister Scientiae (Medical Bioscience) - MSc(MBS)<br>This study investigated the effect of the C. capensis extract (0.001, 0.01, 0.1, 1, 10, 100 1000 μg/ml) on LNCaP prostate cancer, TM3 Leydig and TM4 Sertoli cells for 24 and 96 hours. The following parameters were investigated: morphology, cell viability (XTT), testosterone modulation, DNA fragmentation (TUNEL), lactate dehydrogenase activity (LDH), testosterone production, anti-cancer drug combination. In a separate set of experiments, parameters affecting the initiation, progression and metastasis of cancer were investigated. These includ

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Kukucka, Mark Anthony. "Mechanisms by which hypoxia augments Leydig cell viability and differentiated cell function in vitro /." This resource online, 1993. http://scholar.lib.vt.edu/theses/available/etd-06062008-170416/.

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Afane, Mustapha. "Influence éventuelle des macrophages sur le fonctionnement des cellules de Leydig chez le rat." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376021244.

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Semler-Collery, Ronald. "Ganglioneurome contenant des cellules de Leydig sécrétant de la testostérone : à propos d'un cas." Montpellier 1, 1991. http://www.theses.fr/1991MON11067.

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Khatun, Mst Muslima. "Identification of gonial stem cells and Leydig cells in transgenic medaka (Oryzias latipes) reporter strains." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-118691.

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The mechanism to maintain stem cell properties and to exit into differentiation pathways is a pivotal question in stem cell research. Spermatogonia are the adult stem cells of the male germ line, which are used in biomedical research as a source of undifferentiated cells. The communication between germ line stem cells and specialized somatic cells (Sertoli cells and Leydig cells) plays important roles in stem cell maintenance, germ cell proliferation, and differentiation. With regard to the biology of stem cells and spermatogenesis, the medaka (Oryzias latipes) is used as a teleost model organ

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Webber, Tarryn Jean. "The effect of rooibos and green tea flavnoids on the physiology of TM3 Leydig cells." University of the Western Cape, 2018. http://hdl.handle.net/11394/6333.

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Magister Scientiae - MSc (Medical BioSciences)<br>Camellia sinensis (C.sinesis) and Aspalathus linearis (A.linearis) are popular beverages consumed in many countries. Consumption of these plants may protect against cardiovascular disease, neurodegenerative disease, various cancers and osteoporosis. Previous in vivo studies demonstrated the beneficial effect of C.sinesis and A.linearis on various sperm parameters. However, in vitro studies demonstrated that these plants may possess anti-androgenic properties that finally result in a reduction of testosterone production in TM3 Leydig cells. C.si

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