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1

Johansson, Annie-Maj, and Per-Olof Wickman. "Vad ska elever lära sig angående naturvetenskaplig verksamhet? - En analys av svenska läroplaner för grundskolan under 50 år. "What should students learn about scientific inquiry? A comparative study of 50 years of the Swedish national curricula."." Nordic Studies in Science Education 8, no. 3 (2012): 197–212. http://dx.doi.org/10.5617/nordina.528.

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The purpose of this study is to contribute to an understanding of which changes related to scientific inquiry have been made historically in curriculum documents. A comparative analysis is made of five Swedish national curricula– Lgr 62, Lgr 69, Lgr 80, Lpo 94 and Lgr 11 – during the last 50 years regarding what compulsory school students (school years 1–9) should learn about scientific inquiry. It focuses 1) what students should learn about carrying out scientific inquiries, and 2) what students should learn about the nature of science. All of the curricula examined have aims concerning scien
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Bishop, S. C., J. S. Broadbent, R. M. Kay, I. Rigby, and A. V. Fisher. "The performance of Hereford × Friesian offspring of bulls selected for lean growth rate and lean food conversion efficiency." Animal Science 54, no. 1 (1992): 23–30. http://dx.doi.org/10.1017/s0003356100020523.

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AbstractThe performance of Hereford × Friesian calves sired by Hereford bulls selected for either lean growth rate (LGR) or lean food conversion ratio (LFCR), or by unselected Hereford bulls, was evaluated on 327 calves on three farms over 2 years. Animals started test at 130 days of age on average and remained on test for approximately 300 days, whereupon all animals were slaughtered and carcass dissections were undertaken. Individual food intake was measured on tioo of the farms (189 animals), but only intake per pen of animals was measured on the third farm and individual food intake had to
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Emanuelsson, B. D., W. T. Baisden, N. A. N. Bertler, E. D. Keller, and V. Gkinis. "High-resolution continuous flow analysis setup for water isotopic measurement from ice cores using laser spectroscopy." Atmospheric Measurement Techniques Discussions 7, no. 12 (2014): 12081–124. http://dx.doi.org/10.5194/amtd-7-12081-2014.

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Abstract. Here we present an experimental setup for water stable isotopes (δ18O and δD) continuous flow measurements. It is the first continuous flow laser spectroscopy system that is using Off-Axis Integrated Cavity Output Spectroscopy (OA-ICOS; analyzer manufactured by Los Gatos Research – LGR) in combination with an evaporation unit to continuously analyze sample from an ice core. A Water Vapor Isotopic Standard Source (WVISS) calibration unit, manufactured by LGR, was modified to: (1) increase the temporal resolution by reducing the response time (2) enable measurements on several water st
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Emanuelsson, B. D., W. T. Baisden, N. A. N. Bertler, E. D. Keller, and V. Gkinis. "High-resolution continuous-flow analysis setup for water isotopic measurement from ice cores using laser spectroscopy." Atmospheric Measurement Techniques 8, no. 7 (2015): 2869–83. http://dx.doi.org/10.5194/amt-8-2869-2015.

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Abstract. Here we present an experimental setup for water stable isotope (δ18O and δD) continuous-flow measurements and provide metrics defining the performance of the setup during a major ice core measurement campaign (Roosevelt Island Climate Evolution; RICE). We also use the metrics to compare alternate systems. Our setup is the first continuous-flow laser spectroscopy system that is using off-axis integrated cavity output spectroscopy (OA-ICOS; analyzer manufactured by Los Gatos Research, LGR) in combination with an evaporation unit to continuously analyze water samples from an ice core. A
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Toro, Victor, and Clarissa Aguilar. "LGG-62. SEIZURES IN LOW-GRADE GLIOMAS: CLINICAL AND HISTOPATHOLOGICAL CHARACTERISTICS." Neuro-Oncology 20, suppl_2 (2018): i117—i118. http://dx.doi.org/10.1093/neuonc/noy059.401.

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Nitrini, Ricardo, and A. Spina-França. "Penicilinoterapia intravenosa em altas doses na neurossífilis: estudo de 62 casos II. Avaliação do líqüido cefalorraqueano." Arquivos de Neuro-Psiquiatria 45, no. 3 (1987): 231–41. http://dx.doi.org/10.1590/s0004-282x1987000300003.

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Sessenta e dois casos de neurossífilis sintomática foram tratados com penicilina G, na dose diária de 20 ou 24 milhões de UI. por via intravenosa, durante 15 a 30 dias. O tempo médio de acompanhamento foi de 30 meses. Antes do tratamento, 41 pacientes apresentavam pleocitose ao exame do LCR. Seis meses e doze ou mais meses depois, foi constatada pleocitose em 4 (9,8%) e em 3 pacientes (7,3%), respectivamente. A proteinorraquia e os títulos das reações de Wassermann do soro e do LCR reduziram-se lentamente depois do tratamento. O teor de globulinas gama do LCR e os índices de imunoprodução loca
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7

Saleeva, D. V., and G. D. Zasukhina. "Prospects for using low-dose radiation in the complex therapy for COVID-19." Problems of Virology 66, no. 4 (2021): 252–58. http://dx.doi.org/10.36233/0507-4088-62.

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This review presents the literature data of new approaches for the treatment of COVID-19 with low doses of radiation (LDR). In addition, data on the use of LDR for the treatment of various disorders, in particular pneumonia, a number of inflammatory processes of various etiology, as well as Alzheimer’s disease are discussed. The mechanisms of LDR action are briefly described, associated with the activation of the immune system and antiinflammatory response due to the effect on the processes of oxidative stress, which is reflected in an increase in the activity of cytokines (interleukin- (IL-)
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Da Silva, Adriano da, Rafael José Resende, Tamires Cristina Costa, et al. "ANÁLISE DO POTENCIAL BIOCATALÍTICO DE LIPASE DE CANDIDA RUGOSA IMOBILIZADA EM DIFERENTES SUPORTES." Revista Acta Ambiental Catarinense 18, no. 1 (2020): 10–23. http://dx.doi.org/10.24021/raac.v18i1.5505.

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Neste trabalho é avaliado o potencial biocatalítico da lipase de Candida rugosa (LCR) imobilizada em diferentes suportes: carvão ativado, gesso comercial e sílica gel, visando a produção de biodiesel. O método de imobilização por adsorção foi utilizado na imobilização da LCR nos suportes. A eficiência de imobilização expressa em termos da razão entre a atividade do complexo suporte-LCR e atividade da enzima livre, foram estimados, fornecendo eficiência de 89% para o carvão ativado-LCR, 62% para a sílica gel-LCR e 48% para o gesso-LCR. O complexo carvão ativado-LCR forneceu o maior índice de ac
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Spiridon, Andreea Georgiana, Mădălina Viciriuc, Cristina Vasilița, Alexandru Pintilioaie, and Ovidiu Popovici. "Two genera of platygastroids (Hymenoptera: Platygastroidea) new to the Romanian fauna." Travaux du Muséum National d’Histoire Naturelle “Grigore Antipa” 62, no. 2 (2019): 213–20. http://dx.doi.org/10.3897/travaux.62.e38298.

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This study presents the genera Iphitrachelus Haliday, 1836 and Baryconus Förster, 1856 with the species B. graeffei (Kieffer, 1908), I. lar Haliday, 1836 and I. gracilis Masner, 1957 as new records for the Romanian fauna.
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Marques Boni, Adalgisa Cristina, Halana Carolina Maia, and Marina Peccinin Barbosa. "A importância da prontidão para ler e escrever." Revista Contemporânea de Educação 13, no. 28 (2018): 631–47. http://dx.doi.org/10.20500/rce.v13i26.16634.

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Este estudo teve como objetivo descobrir, através da avaliação e da análise das áreas psicomotora, cognitiva e linguística, se as crianças do 1º ano do Ensino Fundamental I (EFI) precisam desenvolver habilidades para aquisição da leitura e da escrita. 62 crianças do 1º ano do EFI da rede pública da cidade de Limeira efetuaram um Protocolo de Avaliação sobre as habilidades psicomotoras/cognitivas e linguísticas. Observou-se que as habilidades estudadas interferiram na qualidade do processo de alfabetização e não diretamente no aprender ou não a ler e escrever. Assim, corrobora-se a importância
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Bruck, L., S. A. Antoniuk, E. Wittig, and A. Accorsi. "Neurocisticercose na infância: I. diagnóstico clinico e laboratorial." Arquivos de Neuro-Psiquiatria 49, no. 1 (1991): 43–46. http://dx.doi.org/10.1590/s0004-282x1991000100006.

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Foram revisados aspectos clínicos e laboratoriais de 34 casos de neurocisticercose na infância (15 meses a 13 anos). Os principais sintomas foram: hipertensão intracraniana, 21 casos (62%); epilepsia, 20 casos (59%); hemiplegia, 4 casos (12%). A tomografia computadorizada de crânio (TAC) (33 pacientes) mostrou cistos em atividade em 26 (79%) e calcificações em 2 (6%). A reação de fixação de complemento ou imunofluorescência para cisticercose foi reagente em 77% no LCR (20/26 pacientes) e 78% no soro (18/23 pacientes). Pleocitose no LCR ocorreu em 57% dos casos (15/26 pacientes) e eosinofilorra
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Montes, Vizmary, Turki Elarjani, Sami Khairy, David Pinilla, Helena Benito, and Estella Llado. "Valuableness of introduction of laryngeal abductor reflex intraoperative neuromonitoring technique in lower brainstem lesion." Surgical Neurology International 11 (December 11, 2020): 425. http://dx.doi.org/10.25259/sni_431_2020.

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Background: Our aim is to evaluate the use of laryngeal adductor reflex (LAR) for posterior fossa and brainstem surgeries in conjunction with current intraoperative neuromonitoring (IONM) techniques. Case Description: The patient is a 62-year-old woman who complained of decreased hearing on her left side, dizziness, and left facial palsy. After proper investigation, she was found to have a left vestibular schwannoma. She was scheduled for the left retrosigmoid approach and electrodes embedded on the surface of the endotracheal tube were inserted to monitor for LAR. Preoperative baseline monito
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Tweedie, Constance, Caroline Romestaing, Yan Burelle, et al. "Lower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 300, no. 3 (2011): R544—R553. http://dx.doi.org/10.1152/ajpregu.00250.2010.

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Artificial selection in rat has yielded high-capacity runners (HCR) and low-capacity runners (LCR) that differ in intrinsic (untrained) aerobic exercise ability and metabolic disease risk. To gain insight into how oxygen metabolism may have been affected by selection, we compared mitochondrial function, oxidative DNA damage (8-dihydroxy-guanosine; 8dOHG), and antioxidant enzyme activities in soleus muscle (Sol) and gastrocnemius muscle (Gas) of adult and aged LCR vs. HCR rats. In Sol of adult HCR rats, maximal ADP-stimulated respiration was 37% greater, whereas in Gas of adult HCR rats, there
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14

Arini, Nolita Dwi, and Fatmasari Sukesti. "PENGARUH RASIO-RASIO KEUANGAN TERHADAP KINERJA KEUANGAN BANK SYARIAH PERIODE TAHUN 2010-2012 (STUDI KASUS PADA BPRS ARTHA SURYA BAROKAH)." MAKSIMUM 3, no. 1 (2016): 43. http://dx.doi.org/10.26714/mki.3.1.2012.43-62.

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Bank is a financial institution whose main activity is to receive deposits from the public and distribute to third parties to obtain and deliver services in payment traffic. Reality show no economic indicators that can be developed without the help of banking institutions. Therefore, the bank holds a strategic role in the economy. The existence of the banking sector in Indonesia is divided into two types of banks, ie commercial banks and rural banks.The population in this study is the overall financial statement SRB Surya Artha Barokah Semarang. Samples taken in this study is the financial sta
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15

Moore, Douglas F., and Janis I. Curry. "Detection and Identification of Mycobacterium tuberculosis Directly from Sputum Sediments by Ligase Chain Reaction." Journal of Clinical Microbiology 36, no. 4 (1998): 1028–31. http://dx.doi.org/10.1128/jcm.36.4.1028-1031.1998.

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Sputum specimens received for the diagnosis of tuberculosis or other mycobacterial infections were tested by a ligase chain reaction (LCR)-based assay and acid-fast stain and culture techniques. Results from the LCR assay (Abbott LCx Mycobacterium tuberculosis[MTB] Assay) were compared to results from standard culture techniques held for 6 weeks. Four hundred ninety-three specimens from 205 patients suspected of pulmonary tuberculosis were included in the prospective study. Thirty-four (6.9%) of the specimens were culture positive for M. tuberculosis, and 13 (38%) of these were also fluorochro
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16

Kostov, Gancho G., Rossen S, Dimov, and Daniela D. Almeida. "Risk Factors for Anastomotic Leakage after Low Anterior Resection." Folia Medica 62, no. 2 (2020): 290–94. http://dx.doi.org/10.3897/folmed.62.e47727.

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Introduction: Low anterior resection (LAR) is a standard surgical procedure for distal rectal carcinoma that allows creation of a colorectal anastomosis, with anal sphincter preservation and permanent colostomy avoidance. Anastomotic leakage (AL) is a potential complication of LAR present in 3% to 20% of cases leading to a significant increase in postoperative morbidity. AL represents a communication between the intra luminal and extra luminal compartments caused by a violation of the integrity of the intestinal wall. The risk factors of this procedure have been discussed and still remain a co
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Newman, Jamie R., and Mary Anne Cooper. "Lower Gastrointestinal Bleeding and Ischemic Colitis." Canadian Journal of Gastroenterology 16, no. 9 (2002): 597–600. http://dx.doi.org/10.1155/2002/374682.

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OBJECTIVE: To compare the incidence and clinical characteristics of lower gastrointestinal (LGI) bleeding due to ischemic colitis with those with LGI bleeding of other causes.METHODS: A chart review was performed of patients admitted with LGI bleeding to Sunnybrook and Women’s College Health Sciences Centre, Toronto, Ontario, between July 1, 1997 and January 31, 2000.RESULTS: Of 124 patients with LGI bleeding, 24 cases were due to ischemic colitis, 62 to diverticulosis, 11 to inflammatory bowel disease (IBD) and 27 to all other causes (‘others’). The average ages of patients in each group were
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Almaas, Vibeke M., Kristina H. Haugaa, Erik H. Strøm, et al. "Noninvasive assessment of myocardial fibrosis in patients with obstructive hypertrophic cardiomyopathy." Heart 100, no. 8 (2013): 631–38. http://dx.doi.org/10.1136/heartjnl-2013-304923.

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ObjectiveLate gadolinium enhancement cardiac magnetic resonance (LGE-CMR) imaging is the reference standard for non-invasive assessment of fibrosis. In hypertrophic cardiomyopathy (HCM) patients the histological substrate for LGE is still unknown. The aim of this study was to assess the ability of LGE and strain echocardiography to detect type and extent of myocardial fibrosis in obstructive HCM patients undergoing septal myectomy.MethodsThirty-two HCM patients (age 60±10) were included in this cross-sectional study and preoperatively examined by speckle-tracking strain echocardiography and LG
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Catalano, Oronzo, Guido Moro, Alessia Mori, et al. "Cardiac Magnetic Resonance in Stable Coronary Artery Disease: Added Prognostic Value to Conventional Risk Profiling." BioMed Research International 2018 (June 21, 2018): 1–10. http://dx.doi.org/10.1155/2018/2806148.

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Aims. Cardiovascular magnetic resonance (CMR) permits a comprehensive evaluation of stable coronary artery disease (CAD). We sought to assess whether, in a large contemporaneous population receiving optimal medical therapy, CMR independently predicts prognosis beyond conventional cardiovascular risk factors (RF). Methods. We performed a single centre, observational prospective study that enrolled 465 CAD patients (80% males; 63±11 years), optimally treated with ACE-inhibitors/ARB, aspirin, and statins (76-85%). Assessments included conventional evaluation (clinical history, atherosclerosis RF,
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Ungerer, Mark C., Solveig S. Halldorsdottir, Michael D. Purugganan, and Trudy F. C. Mackay. "Genotype-Environment Interactions at Quantitative Trait Loci Affecting Inflorescence Development in Arabidopsis thaliana." Genetics 165, no. 1 (2003): 353–65. http://dx.doi.org/10.1093/genetics/165.1.353.

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Abstract Phenotypic plasticity and genotype-environment interactions (GEI) play a prominent role in plant morphological diversity and in the potential functional capacities of plant life-history traits. The genetic basis of plasticity and GEI, however, is poorly understood in most organisms. In this report, inflorescence development patterns in Arabidopsis thaliana were examined under different, ecologically relevant photoperiod environments for two recombinant inbred mapping populations (Ler × Col and Cvi × Ler) using a combination of quantitative genetics and quantitative trait locus (QTL) m
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Starostina, S. V., V. M. Makhov, O. A. Storonova та ін. "Сapabilitу of 24-hour esophageal pH-impedance monitoring in the diagnosis of GERD-associated laryngeal diseases". Meditsinskiy sovet = Medical Council, № 16 (14 листопада 2020): 62–72. http://dx.doi.org/10.21518/2079-701x-2020-16-62-72.

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Extraesophageal manifestations of gastroesophageal reflux disease (GERD), despite the improvement of methods of diagnosis and treatment of patients with this pathology, still remain an urgent problem of medicine and cause increased attention of clinicians and researchers. In some cases, patients with GERD do not present typical complaints of heartburn, regurgitation; the disease may manifest extraesophageal manifestations, such as chronic cough, hoarseness, reflux laryngitis, and others caused by the presence of laryngopharyngeal reflux (LFR) – inflammation of the mucous membrane of the upper
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Hurtado Monroy, Rafael, Pablo Vargas-Viveros, and Carrillo Munoz Silvia. "Imatinib (IMA) Low Dose Reduction Program (LDR) in Chronic Myeloid Leukemia Ph+ (CML Ph+) in a Single Reference Institution in Mexico City. Ongoing Preliminary Results." Blood 134, Supplement_1 (2019): 5921. http://dx.doi.org/10.1182/blood-2019-130873.

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Imatinib (IMA) total stop therapy has interesting worldwide results in selected patients (pts) with CML Ph+ who have achieved 4 to 5 log reduction of BCR/ABL copies, however there is no information of LDR. The observation that IMA intolerance induces a dose reduction in our cases and, the fact that during the follow-up of their RT-PCR for BCR/ABL remains in > 4 log reduction after two years, was the rationale for an open prospective LDR program with the main objective to optimizing CML Ph+ treatment due to economical limitations and drug availability in Mexico. Herein we report our ongoing
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De Gobbi Porto, Fábio Henrique, Lívia Spíndola, Maira Okada De Oliveira, et al. "A score based on screening tests to differentiate mild cognitive impairment from subjective memory complaints." Neurology International 5, no. 3 (2013): 16. http://dx.doi.org/10.4081/ni.2013.e16.

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It is not easy to differentiate patients with mild cognitive impairment (MCI) from subjective memory complainers (SMC). Assessments with screening cognitive tools are essential, particularly in primary care where most patients are seen. The objective of this study was to evaluate the diagnostic accuracy of screening cognitive tests and to propose a score derived from screening tests. Elderly subjects with memory complaints were evaluated using the Mini Mental State Examination (MMSE) and the Brief Cognitive Battery (BCB). We added two delayed recalls in the MMSE (a delayed recall and a late-de
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Al Efraij, Khalid S., Mohammed A. Aljama, and Hagen F. Kennecke. "Effect of dose intensification (DI) of octreotide-LAR (O-LAR) among symptomatic patients with neuroendocrine tumors (NETs)." Journal of Clinical Oncology 32, no. 3_suppl (2014): 299. http://dx.doi.org/10.1200/jco.2014.32.3_suppl.299.

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299 Background: O-LAR 20 to 30 mg IM monthly (qM) is approved for the management of symptomatic NETs. While higher doses are sometimes used for improved symptom control, the benefit of this is not well described. The objectives of the study were to evaluate pre-DI and post-DI symptom, biomarker and tumor size among patients who received O-LAR 40-60 mg qM. Methods: With approval of the BC Cancer Agency research ethics committee the charts of all referred patients with NETs who received O-LAR 40-60 mg qM between 2005 and 2001 were reviewed. Symptom severity was graded on a 4 point scale and any
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Sethukavalan, Perakaa, Patrick Cheung, Gerard Morton, et al. "How does stereotactic body radiotherapy compare to standard external beam radiotherapy or low-dose rate brachytherapy for low-risk prostate cancer?" Journal of Clinical Oncology 31, no. 15_suppl (2013): e16070-e16070. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e16070.

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e16070 Background: Stereotactic body radiotherapy (SBRT) is an emerging radiotherapy technique that appears to be efficacious, well tolerated and convenient. However, outcomes for patients treated with SBRT are unknown compared to more conventional radiation options for patients with prostate cancer. The purpose of this study is to evaluate and compare late toxicities and biochemical disease-free survival (bDFS) of low risk prostate cancer patients treated SBRT (35Gy/5 fractions), standard external beam radiotherapy (STND; median 76Gy/38 fractions) or low-dose brachytherapy (LDR; iodine-125, 1
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Kelle, Sebastian, Kelly Schlendorf, Glenn A. Hirsch, et al. "Gadolinium Enhanced MR Coronary Vessel Wall Imaging at 3.0 Tesla." Cardiology Research and Practice 2010 (2010): 1–9. http://dx.doi.org/10.4061/2010/856418.

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Purpose. We evaluated the influence of the time between low-dose gadolinium (Gd) contrast administration and coronary vessel wall enhancement (LGE) detected by 3T magnetic resonance imaging (MRI) in healthy subjects and patients with coronary artery disease (CAD).Materials and Methods.Four healthy subjects (4 men, mean age29 ± 3years and eleven CAD patients (6 women, mean age61±10years) were studied on a commercial 3.0 Tesla (T) whole-body MR imaging system (Achieva 3.0 T; Philips, Best, The Netherlands). T1-weighted inversion-recovery coronary magnetic resonance imaging (MRI) was repeated up
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Mair, Maximilian J., Sahra Pajenda, Aysegül Ilhan-Mutlu, et al. "Soluble PD-L1 is associated with local and systemic inflammation markers in primary and secondary brain tumours." ESMO Open 5, no. 6 (2020): e000863. http://dx.doi.org/10.1136/esmoopen-2020-000863.

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BackgroundImmune-modulatory treatments have so far shown limited clinical activity in primary brain tumours. We aimed to investigate soluble programmed death receptor ligand 1 (sPD-L1) as systemic inflammation parameter in patients with brain tumour.MethodsEDTA plasma was collected from 81 glioma (55 glioblastoma (GBM), 26 lower-grade glioma (LGG)), 17 meningioma and 44 brain metastasis (BM) patients and 24 controls. sPD-L1 concentrations were determined by ELISA. Correlations with the local tumour microenvironment were assessed by immunohistochemical analysis for PD-L1, CD3 and CD8.ResultssPD
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Silva-Vergara, Mario León, Cláudio de Oliveira Vieira, João Henrique Castro, et al. "Achados neurológicos e laboratoriais em população de área endêmica para teníase-cisticercose, Lagamar, MG, Brasil (1992-1993)." Revista do Instituto de Medicina Tropical de São Paulo 36, no. 4 (1994): 335–42. http://dx.doi.org/10.1590/s0036-46651994000400006.

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Realizou-se um inquérito clínico-epidemiológico em área endêmica para teníase-cisticercose. Foram examinados 1080 (32,2%) indivíduos da população total, encontrando-se 198 (18,3%) indivíduos referindo antecedente de teníase, e 103 (9,5%) apresentaram história anterior ou atual de convulsões. Destes últimos, 39 (37,8%) referiram início das crises na vida adulta, e 62 (60%) foram avaliados laboratorialmente. Em 21 (33,8%) casos, o resultado da tomografia mostrou calcificações intracranianas compatíveis com neurocisticercose, em número e localização variáveis, mas sem evidência de atividade da do
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Franchi, Giulia M., Chiara Cappelletti, Valentina V. Villa, Emanuele Bosi, and Marco F. Manzoni. "Role of high dose octreotide LAR for the treatment of GEP-NETs." Clinical Management Issues 3, no. 1 (2009): 7–14. http://dx.doi.org/10.7175/cmi.v3i1.555.

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Neuroendocrine Tumours (NETs) are a heterogeneous group of rare neoplasms that account for 0,5% of all malignancies. The increased incidence observed in the last few decades may be accounted for by increased awareness, improved diagnostic tools and a revision in the definition. The main primary sites are the gastro-entero-pancreatic (GEP) tract (62-67%), and the lung (22-27%). In patients with GEP-NETs, the strongest predictor of 5-years survival is the staging. An adequate clinical management of GEP-NETs should be multidisciplinary and should aim at assuring a good quality of life. Somatostat
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Larsen, Terje H., Marie Stugaard, Svein Rotevatn, Ottar Nygård, and Jan Erik Nordrehaug. "Clinical Significance of Late Enhancement and Regional Wall Remodeling Assessed by ST Magnetic Resonance Imaging." Clinical Medicine Insights: Cardiology 9 (January 2015): CMC.S20291. http://dx.doi.org/10.4137/cmc.s20291.

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Background Clinical follow-up studies comparing left ventricular (LV) function and late gadolinium enhancement (LGE) by high-field 3T cardiac magnetic resonance (CMR) are of general interest due to the increased use of 3T scanners. In this study, the occurrence of LGE and LV regional wall remodeling (RWR) was assessed by 3T CMR in patients undergoing coronary angiography for suspected stable coronary artery disease (CAD). Materials and Methods Analysis of myocardial viability by LGE was performed at the segmental level. LVRWR was identified by a significant reduction (≥50%) of the wall thickne
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Bender, M. A., Davide Bau', Tobias Ragoczy та ін. "Integrating Structural and Functional Studies Leads to a New Model of β-Globin Activation That Suggests Distinct Initiation and Maintenance States". Blood 118, № 21 (2011): 349. http://dx.doi.org/10.1182/blood.v118.21.349.349.

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Abstract Abstract 349 The human and mouse β-globin loci share a conserved structure in which the locus control region (LCR) and genes are flanked by three CTCF bound DNaseI hypersensitive sites (HSs); 3‘HS1 downstream, and 5‘HS5 and human and mouse orthologues HS-111 or HS-62 upstream. In mice HS-62 and 3‘HS1 delineate a DNase sensitive domain. During erythroid differentiation, high-level expression of the β-globin locus is associated with LCR-dependent re-localization of the locus from the nuclear periphery to the nucleoplasm, where it associates with foci of serine-phosphorylated PolII deeme
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Scott, Aba Anoa, Joel Yarney, Verna Vanderpuye, et al. "Outcomes of patients with cervical cancer treated with low- or high-dose rate brachytherapy after concurrent chemoradiation." International Journal of Gynecologic Cancer 31, no. 5 (2021): 670–78. http://dx.doi.org/10.1136/ijgc-2020-002120.

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ObjectiveThe majority of patients with cervical cancer in Ghana present with locally advanced disease. In October 2014, high-dose rate (HDR) brachytherapy was introduced at the National Center for Radiotherapy, Accra after years of using low-dose rate (LDR) brachytherapy. The aim of this study was to compare the treatment outcomes of patients treated with LDR versus HDR brachytherapy.MethodsPatients with cervical cancer treated from January 2008 to December 2017 were reviewed. Those with stage IB–IIIB who received chemoradiation plus brachytherapy were included in the study. Post-operative pat
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Weber, Jill M., Max Feldman, Larry Kvols, and Jonathan R. Strosberg. "Above-label doses of octreotide-LAR in patients with metastatic small-intestinal carcinoid tumors." Journal of Clinical Oncology 30, no. 15_suppl (2012): e14579-e14579. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e14579.

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e14579 Background: Octreotide LAR is indicated for treatment of the malignant carcinoid syndrome, and has been studied at doses of 10-30mg intramuscularly every 4 weeks. It has also been proven to delay time to progression of metastatic midgut carcinoid tumors at a dose of 30mg every 4 weeks. In clinical practice, higher doses are often prescribed for patients who experience refractory carcinoid syndrome (flushing and/or diarrhea) or tumor growth while on the maximal labeled dose. We performed a retrospective, longitudinal review of octreotide LAR administration at a tertiary institution to de
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Stephenson, Erin J., Nigel K. Stepto, Lauren G. Koch, Steven L. Britton, and John A. Hawley. "Divergent skeletal muscle respiratory capacities in rats artificially selected for high and low running ability: a role for Nor1?" Journal of Applied Physiology 113, no. 9 (2012): 1403–12. http://dx.doi.org/10.1152/japplphysiol.00788.2012.

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Inactivity-related diseases are becoming a huge burden on Western society. While there is a major environmental contribution to metabolic health, the intrinsic properties that predispose or protect against particular health traits are harder to define. We used rat models of inborn high running capacity (HCR) and low running capacity (LCR) to determine inherent differences in mitochondrial volume and function, hypothesizing that HCR rats would have greater skeletal muscle respiratory capacity due to an increase in mitochondrial number. Additionally, we sought to determine if there was a link be
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35

Lim, Yiting, Mohammad Hedayati, Akil Merchant, Yonggang Zhang, Theodore DeWeese, and William Matsui. "Improved Survival and Recovery of Hematopoiesis Following Lethal Radiation by Chloroquine-Mediated Activation of ATM." Blood 116, no. 21 (2010): 2228. http://dx.doi.org/10.1182/blood.v116.21.2228.2228.

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Abstract Abstract 2228 Irreversible bone marrow damage and impaired blood formation is the primary cause of death following exposure to high doses of radiation. Moreover, the rate at which radiation is delivered may have a profound impact on cytotoxicity; prolonged exposure at a low dose-rate (LDR; 9.4 cGy/hr) has been found to induce greater cell death than the same total dose given at a high dose-rate (HDR; 4500 cGy/hr). Few non-toxic agents are presently available that can offer substantial protection against radiation induced bone marrow failure and death, especially during LDR exposure. W
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Shetty, Vanaja P., Anju V. Wakade, Sunil D. Ghate, and Vivek V. Pai. "Clinical, bacteriological and histopathological study of 62 referral relapse cases between Jan 2004 and Dec 2009 at the Foundation for Medical Research, Mumbai." Leprosy Review 82, no. 3 (2011): 235–43. http://dx.doi.org/10.47276/lr.82.3.235.

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37

Barak, Y., Y. Baruch, and S. Tadger. "Symptomatic Remission Amongst Elderly Schizophrenia Patients Treated with Long-acting Risperidone." European Psychiatry 24, S1 (2009): 1. http://dx.doi.org/10.1016/s0924-9338(09)71235-0.

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Background:In elderly schizophrenia patients remission is difficult to determine due to long disease duration, exposure to differing treatments, long-standing side-effects, non-adherence, cognitive decline and physical co-morbidity.Methods:Retrospective chart review of elderly (60+ years) schizophrenia patients admitted to a university affiliated tertiary psychiatric center. Patients were experiencing an exacerbation at admission. Remission criteria were as defined by the APA's “Remission in Schizophrenia Working Group”. Clinical status and improvement were quantified using the Clinical Global
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Ruchlemer, Rosa, Deborah Elstein, Eti Broide, Constantine Reinus, Hannah Maayaan, and Ari Zimran. "Gaucher Disease and LGL Proliferations: Provocative Commonality?" Blood 118, no. 21 (2011): 1100. http://dx.doi.org/10.1182/blood.v118.21.1100.1100.

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Abstract Abstract 1100 Large granular lymphocytes(LGL)which may be of T or NK phenotype, normally account for 10–15% of peripheral blood(PB)lymphocytes. T-LGL leukemia is a clonal expansion of antigen-primed competent cytotoxic-T-lymphocytes(CTL)which is unique in that these cells retain many phenotypic and functional properties of normal cytotoxic effector T cells. Sphingolipid-mediated signaling has been shown to have a role in long-term survival of CTLs. The diagnosis of T-LGL leukemia requires proof of clonality, yet clonal T-LGL proliferations may occur in normal individuals with autoimmu
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Ardicli, Sena, Hale Samli, Buse Vatansever, Bahadir Soyudal, Deniz Dincel, and Faruk Balci. "Comprehensive assessment of candidate genes associated with fattening performance in Holstein–Friesian bulls." Archives Animal Breeding 62, no. 1 (2019): 9–32. http://dx.doi.org/10.5194/aab-62-9-2019.

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Abstract. The objective of this study was to determine the association of single nucleotide polymorphisms (SNPs) in selected candidate genes with fattening performance traits in a commercial cattle herd. Fifteen SNPs in 12 candidate genes (LEP, FABP4, DGAT1, TG, IGF1, IGF1R, MYF5, LGB, CAPN1, CAST, GHR, and OLR1) were evaluated in 296 purebred Holstein–Friesian bulls using PCR-RFLP (polymerase chain reaction – restriction fragment length polymorphism). Associations between each segregating SNP and genetic merit for fattening performance were quantified using linear mixed models. Traits include
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Da Silva, Maria Carla, Eliane Correa Miotto, Mara Cristina Souza De Lucia, and Paulo Henrique Pires De Aguiar. "Investigação neuropsicológica pré-operatória em pacientes com glioma de baixo grau." JBNC - JORNAL BRASILEIRO DE NEUROCIRURGIA 18, no. 3 (2018): 35–39. http://dx.doi.org/10.22290/jbnc.v18i3.635.

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Objetivo: Os gliomas de baixo grau (LGG) são tumores decrescimento lento e com um comportamento clínico heterogêneo,onde muitos pacientes não apresentam sintomas neurológicosou cognitivos observáveis, entretanto, quando taispacientes são submetidos a tratamento químioterápico ouradioterápico, observam-se em alguns casos alterações cognitivasmuitas vezes não associadas apenas com o tratamentorecebido. Nestes casos há a possibilidade de tais pacientes jáapresentarem previamente ao tratamento alterações cognitivassutis identificadas apenas através de exame neuropsicológico.O objetivo deste estudo
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Mulyanto, Agus, Yeni Agus Nurhuda, and Imam Khoirurosid. "Sistem Kendali Lampu Rumah Menggunakan Smartphone Android." Jurnal Teknoinfo 11, no. 2 (2017): 48. http://dx.doi.org/10.33365/jti.v11i2.28.

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Pemanfaatan energi listrik dewasa ini kurang efektif khususnya dalam hal penerangan penggunaan lampu di dalam ruangan, dimana sering kali dijumpai keadaan energi listrik yang dipakai untuk menerangi ruangan terbuang secara percuma karena kelalaian pemakai yang lupa untuk memadamkan kembali lampu ruangan apabila sudah tidak diperlukan lagi. Maka pada penelitian ini di buat sebuah prototype Sistem Kendali Lampu Ruangan yang dapat dikendalikan melalui Smartphone Android dengan menggunakan media komunikasi Bluetooth HC-05, dan mikrokontroler Arduino Uno R3 serta sensor LDR. Tujuan penelelitian ini
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Gang, Liu, Zeng Mu, Ma Zenglin, et al. "Cardiac Magnetic Resonance Quantitative Tissue Markers in the Clinical Application Value for the Diagnosis of Acute Myocarditis." Journal of Medical Imaging and Health Informatics 8, no. 9 (2018): 1751–56. http://dx.doi.org/10.1166/jmihi.2018.2523.

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Objectives: To determine the value of cardiac magnetic resonance (CMR) quantitative tissue markers in the diagnosis of acute myocarditis, compared with the traditional Lake-Louise criteria (LLC). Methods: Totally 35 cases of patients diagnosed as acute myocarditis in Beijing Anzhen Hospital and 35 healthy volunteers were enrolled in our study, from May 2014 to August 2016. CMR protocol included quantitative assessment of T1 relaxation times using modified Look-Locker inversion recovery (MOLLI), extracellular volume fraction (ECV), T2 relaxation times. Established Lake-Louise criteria (LLC) con
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Kacena, Katherine A., Sean B. Quinn, M. René Howell, Guillermo E. Madico, Thomas C. Quinn, and Charlotte A. Gaydos. "Pooling Urine Samples for Ligase Chain Reaction Screening for Genital Chlamydia trachomatis Infection in Asymptomatic Women." Journal of Clinical Microbiology 36, no. 2 (1998): 481–85. http://dx.doi.org/10.1128/jcm.36.2.481-485.1998.

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The accuracy of pooling urine samples for the detection of genitalChlamydia trachomatis infection by ligase chain reaction (LCR) was examined. A model was also developed to determine the number of samples to be pooled for optimal cost savings at various population prevalences. Estimated costs included technician time, laboratory consumables, and assay costs of testing pooled samples and retesting individual specimens from presumptive positive pools. Estimation of population prevalence based on the pooled LCR results was also applied. After individual urine specimens were processed, 568 specime
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Zellars, R. C., S. G. Hilsenbeck, G. M. Clark, et al. "Prognostic Value of p53 for Local Failure in Mastectomy-Treated Breast Cancer Patients." Journal of Clinical Oncology 18, no. 9 (2000): 1906–13. http://dx.doi.org/10.1200/jco.2000.18.9.1906.

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PURPOSE: The loss of p53 function is a recognized adverse prognostic factor in invasive breast cancer. Several studies have shown a relationship between the nuclear accumulation of p53 protein (a surrogate marker of p53 inactivation) and poor disease-free and overall survival. In general, however, these studies did not report the prognostic value of p53 for local failure, which we have therefore assessed retrospectively here. MATERIALS AND METHODS: Accumulation of p53 protein was evaluated by immunohistochemistry in 1,530 mastectomy-treated breast cancer patients (259 radiation therapy [RT]– a
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45

Dinter, Martin T. "Sententiae na épica latina." Letras Clássicas, no. 14 (December 19, 2010): 51. http://dx.doi.org/10.11606/issn.2358-3150.v0i14p51-62.

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Este artigo examina as <em>sententiae</em>, um expediente retórico bastante negligenciado da épica latina, em Virgílio e Lucano. Enquanto as sententiae de Virgílio são frequentemente citadas por autores posteriores, Lucano, em particular, ficou famoso na Antiguidade por suas <em>sententiae</em> altamente retóricas (<em>Inst. Or.</em> 10.1.90). Lucano concentra seus esforços no nível sintático a fim de criar frases únicas e memoráveis, as quais asseguram o <em>Nachleben</em> de seu épico – haja vista que são extraíveis de seus contextos originais
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46

Herwinanto, Erfan. "PERBANDINGAN KINERJA BANK SWASTA DI INDONESIA BERDASARKAN PEMENUHAN MODAL MINIMUM." Jurnal Riset Akuntansi dan Keuangan 11, no. 2 (2015): 129. http://dx.doi.org/10.21460/jrak.2015.112.13.

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This study aims at revealing the bank capital influence its operational activities. This study employssecondary datum which is obtained from bank indonesia. From the existing data banks, 171 financialstatement of banks are used for sample from 2005 to 2007, which breakdown in 2005 consist 62, 2006consist 56, 2007 consist 53 financial statement. In order to measure banks activities, CAMELScomponent is conducted in accordance with bank indonesia regulations. Based on the analysis at allbanks on 2005-2007, it revals that KPPM component, capital component, NIM component, betweenbank and its capita
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47

Hata, Jessica, Mustafa Barbour, and Michael Angelo Huang. "LGG-02. PEDIATRIC LOW-GRADE GLIOMA RISK STRATIFICATION IN THE MOLECULAR ERA." Neuro-Oncology 23, Supplement_1 (2021): i31. http://dx.doi.org/10.1093/neuonc/noab090.126.

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Abstract Background Pediatric low-grade gliomas (LGG), in particular those not amenable to surgical resection, are a therapeutic challenge owing to their heterogeneity in clinical behavior. Identification of the RAS/MAPK pathway as a universal feature of these tumors has led to an improved understanding and the development of targeted therapeutics. We examined the impact of known biological and novel molecular risk factors on patient outcomes at our institution. Methods We retrospectively reviewed risk factors and clinical outcomes in 38 LGG cases diagnosed by histopathology at Norton Children
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Widhalm, Georg, Jonathan Olson, Jonathan Weller, et al. "The value of visible 5-ALA fluorescence and quantitative protoporphyrin IX analysis for improved surgery of suspected low-grade gliomas." Journal of Neurosurgery 133, no. 1 (2020): 79–88. http://dx.doi.org/10.3171/2019.1.jns182614.

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OBJECTIVEIn patients with suspected diffusely infiltrating low-grade gliomas (LGG), the prognosis is dependent especially on extent of resection and precision of tissue sampling. Unfortunately, visible 5-aminolevulinic acid (5-ALA) fluorescence is usually only present in high-grade gliomas (HGGs), and most LGGs cannot be visualized. Recently, spectroscopic probes were introduced allowing in vivo quantitative analysis of intratumoral 5-ALA–induced protoporphyrin IX (PpIX) accumulation. The aim of this study was to intraoperatively investigate the value of visible 5-ALA fluorescence and quantita
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XU, XIANGMIN, A. B. BONDS, and VIVIEN A. CASAGRANDE. "Modeling receptive-field structure of koniocellular, magnocellular, and parvocellular LGN cells in the owl monkey (Aotus trivigatus)." Visual Neuroscience 19, no. 6 (2002): 703–11. http://dx.doi.org/10.1017/s0952523802196027.

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Most cells in the retina and lateral geniculate nucleus (LGN) of primates have a concentric center/surround receptive-field organization. Details of the relationship between center and surround often can be used to predict how cells respond to visual stimuli. Models of the receptive-field organization and center/surround relationships also are useful when comparing cell classes. In the present study, we used the difference-of-Gaussians (DOG) model to quantitatively examine and compare the receptive-field center/surround organization of koniocellular (K), magnocellular (M), and parvocellular (P
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Diaz, M., J. Jo, and D. Schiff. "P14.23 Risk of venous thromboembolism (VTE) in grade II-IV gliomas as a function of molecular subtype." Neuro-Oncology 21, Supplement_3 (2019): iii71—iii72. http://dx.doi.org/10.1093/neuonc/noz126.258.

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Abstract BACKGROUND VTE affects up to 30% of patients with glioblastoma (GBM, WHO grade IV), but little is known about its incidence in lower-grade gliomas (LGG, WHO grade II-III). It has been suggested that isocitrate dehydrogenase (IDH) mutation status dramatically decreases the incidence of VTE in glioma patients, through a combination of F3 promoter hypermethylation leading to lower expression of the procoagulant protein tissue factor, and an increased production of D-2-hydroxyglutarate, which has anticoagulant properties (Unruh et al, 2016). Our objective was to determine the incidence of
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