Journal articles: 'Libidibia'

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Oliveira, Glauber Palma de, Letícia da Silva Soares Gomes, Gisely Naura Venâncio, Emerson Silva Lima, Tatiane Pereira de Souza, Maria Fulgência Costa Lima Bandeira, Carina Toda, and Nikeila Chacon de Oliveira Conde. "Citotoxicidade de uma formulação em orabase de Libidibia Ferrea." Research, Society and Development 10, no. 10 (August 7, 2021): e133101018713. http://dx.doi.org/10.33448/rsd-v10i10.18713.

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A Libidibia Ferrea é uma planta que possui inúmeras propriedades terapêuticas comprovadas para prevenção e tratamento de afecções bucais. Objetivo: Avaliar uma formulação em orabase de Libidibia ferrea quanto a citotoxicidade. Metodologia: O teste de hemólise foi realizado através do método de avaliação qualitativa de hemoglobina livre e o teste de cultura de células de fibroblastos através do método de Alamar Blue. Foram testados o extrato da casca do caule, veículo da formulação, seus adjuvantes e a formulação orabase. Resultados: No teste de hemólise tanto o extrato da casca do caule quanto a formulação e seus componentes não apresentaram hemólise ao avaliar visualmente o sobrenadante de cada poço. No teste de Alamar Blue não apresentou toxicidade em nenhuma das soluções testadas. Conclusão: Baseado nos resultados, o extrato da casca do caule e a formulação em orabase de Libidibia ferrea L. não foram tóxicos quando testados em hemácias e cultura de células de fibroblastos.

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Giménez, Ana M., Graciela Bolzon Muniz Bolzon Muniz, Juana G. Moglia Moglia, and Silvana Nigosky. "Ecoanatomia del ébano sudamericano: “guayacán” (Libidibia paraguariensis, Fabaceae)." Boletín de la Sociedad Argentina de Botánica 52, no. 1 (May 11, 2017): 45–54. http://dx.doi.org/10.31055/1851.2372.v52.n1.16907.

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La madera de Libidibia paraguariensis (D. Parodi) G. P. Lewis “guayacán”, es homóloga a la de Diospyros ebenum J. Koenig “ébano”. Es una madera cuyas características tecnológicas y organolépticas le otorgan extraordinaria calidad y gran potencial futuro. Por este motivo los objetivos del trabajo fueron: (1) profundizar el conocimiento de las cualidades anatómicas del leño y la corteza;(2) analizar la relación albura-duramen y (3) caracterizar los anillos de crecimiento. El estudio se realizó empleando muestras provenientes de Guasayán, Santiago del Estero y Villa Rio Bermejito, Chaco (Argentina). Seis árboles de cada sitio, fueron seleccionados al azar. Se consiguió una rodaja del fuste principal de cada individuo, a una altura de 1,3 m. Se realizó la descripción del leño y de la corteza. El carácter anatómico relevante con alto valor diagnóstico resultó la estratificación completa de los radios. Los anillos son demarcados, con un incremento radial (IR) medio de 3,57 mm, el crecimiento es lento a medio, con albura gruesa. El leño presenta características correspondientes a una especie mesomórfica. La corteza externa con una o dos peridermis acumuladas, presenta dehiscencia en placas delgadas, lo cual resulta un elemento diagnóstico para la determinación a campo.

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Lima, Maria Joanellys dos Santos, Mirella Yasmim Correia da Silva, Karolynne Rodrigues de Melo, Beatriz de França Chagas, Larissa Araújo Rolim, Pedro José Rolim Neto, and Rosali Maria Ferreira da Silva. "CARACTERIZAÇÃO DO EXTRATO SECO DE LIBIDIBIA FERREA PARA TERAPIA ANTIHIPERGLICEMIANTE / CHARACTERIZATION OF THE LIBIDIBIA FERREA DRY EXTRACT FOR ANTIHIPERGLICEMIAN THERAPY." Brazilian Journal of Development 6, no. 12 (2020): 27488–97506. http://dx.doi.org/10.34117/bjdv6n12-297.

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Kobayashi, Yuri Teiichi da Silva, Vívian Tavares de Almeida, Talita Bandeira, Bianca Nascimento de Alcântara, Andressa Santa Brígida da Silva, Wagner Luiz Ramos Barbosa, Paula Barbosa da Silva, Maria Vivina Barros Monteiro, and Milton Begeres de Almeida. "Avaliação fitoquímica e potencial cicatrizante do extrato etanólico dos frutos de Jucá (Libidibia ferrea) em ratos Wistar." Brazilian Journal of Veterinary Research and Animal Science 52, no. 1 (April 13, 2015): 34. http://dx.doi.org/10.11606/issn.1678-4456.v52i1p34-40.

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Libidibia ferrea é uma planta muito utilizada popularmente para fins terapêuticos, inclusive para acelerar processos de cicatrização de feridas cutâneas. O presente trabalho pesquisou a composição química e avaliou o potencial cicatrizante do extrato etanólico dos frutos de L. ferrea (Mart. ex Tul.) em ratos. Foram utilizados 24 ratos Wistar divididos em quatro grupos. De todos os animais, foi retirado um fragmento de pele do dorso e cada grupo recebeu um tratamento diferente: solução de NaCl 0,9%, digliconato de clorexidina 1%, extrato etanólico dos frutos de Libidibia ferrea 12,5% e 50%. O processo de cicatrização foi avaliado macro e microscopicamente. Para a cicatrização de pele em ratos o extrato etanólico dos frutos de L. ferrea a 12,5% é significativamente mais eficiente do que a 50%. Saponinas, ácidos orgânicos, açúcares redutores, fenóis e taninos, sesquiterpenolactonas e outras lactonas, e antraquinonas foram encontrados no extrato.

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Lima, Maria Joanellys dos Santos, Thaís Pachêco Freitas, Rodrigo Silva de Oliveira, Larissa Araújo Rolim, Pedro José Rolim Neto, Maria Bernadete Sousa Maia, and Rosali Maria Ferreira da Silva. "DESENVOLVIMENTO TECNOLÓGICO DE CÁPSULAS À BASE DE LIBIDIBIA FERREA PARA TERAPIA ANTIHIPERGLICEMIANTE / TECHNOLOGICAL DEVELOPMENT OF CAPSULES BASED ON LIBIDIBIA FERREA FOR ANTIHIPERGLICEMIANTE THERAPY." Brazilian Journal of Development 6, no. 12 (2020): 95271–88. http://dx.doi.org/10.34117/bjdv6n12-131.

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Jesus, Janisson Batista de, Robério Anastácio Ferreira, and Dráuzio Correia Gama. "BEHAVIOR OF THE EMERGENCE OF NATIVE FOREST SEEDLINGS FOR THE PURPOSE OF RECOVERY OF THE RIPARIAN FOREST." FLORESTA 49, no. 1 (December 17, 2018): 057. http://dx.doi.org/10.5380/rf.v49i1.56202.

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Understanding the behavior of the emergence of native forest seeds is essential to achieve greater successes in forest recovery. Therefore, this study aimed to evaluate the emergence of native forest species (Cassia grandis L.F., Cecropia pachystachya Trec., Enterolobium contortisiliquum (Vell.) Morong, Guazuma ulmifolia Lam., and Libidibia ferrea var. leiostachya (Benth.) L.P.Queiroz.) in riparian areas of the Piauitinga River, in the municipality of Lagarto (state of Sergipe, Brazil). The experiment was carried out in a randomized block design (DBC) with four blocks in triple scheme (4 x 2 x 6): four forest species emerged (Cassia grandis, Enterolobium contortisiliquum, Guazuma ulmifolia, Libidibia ferrea var. leiostachya), with and without treatment to overcome dormancy, evaluated every fortnight for 90 days (6 periods). It was verified by the statistical analysis that the four species that had emergencies interacted in the two treatments used throughout the six evaluation periods. The species, in both treatments, presented a large number of seeds emerged in the first weeks after sowing, reducing over time. The species studied have a characteristic pattern of emergence over time, considering both seeds with and without treatment to overcome dormancy.

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Venâncio, Gisely Naura, Isis Costa Rodrigues, Tatiane Pereira de Souza, Raquel de Oliveira Marreiro, Maria Fulgência Costa Lima Bandeira, and Nikeila Chacon de Oliveira Conde. "Herbal mouthwash based on Libidibia ferrea: microbiological control, sensory characteristics, sedimentation, pH and density." Revista de Odontologia da UNESP 44, no. 2 (April 2015): 118–24. http://dx.doi.org/10.1590/1807-2577.1064.

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Introduction Phytotherapy is the study of herbal medicines and their applicability to cure diseases in general, being a therapeutic method which can be used for the prevention and treatment of mouth diseases. Among the herbal studied, the Libidibia ferrea, known as jucá or ironwood, is widely used in folk medicine by presenting anti-inflammatory, analgesic, antimicrobial and antipyretic therapeutic properties. Objective To evaluate in vitro pharmacological stability of the Libidibia ferrea extract’s mouthwash (INPA - 228 022). Material and method It was held the mouthwash microbiological control by determining the total number of microorganisms and Salmonella sp, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus; stability characteristics (color, odor, brightness and consistency), sedimentation test (centrifuge), the pH measurement (pH meter) and density evaluation (pycnometer) were analyzed. Result The mouthwash showed to be absent from microorganisms and no changes were observed in the organoleptics and sedimentation characteristics. The average pH values were 6.21, 6.15 and 5.85 at 0, 30 and 60 days, respectively, and 1.029, 1.033 and 1.035 g/ mL density values, respectively, without interfering with the final characteristic of the formulation. Conclusion The mouthwash presented pharmacological stability and quality conditions.

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Grisi, Cristiani Viegas Brandão, Angela Maria Tribuzy de Magalhães Cordeiro, Malanna Kauanne Gomes do Nascimento, Simone Alves Monteiro da Franca, Sulamita Moreira Maia Freire, Carolina Lima Cavalcanti de Albuquerque, Adriano da Silva Marques, and Gilmar Trindade de Araújo. "Potencial antioxidante e estabilidade do bioaditivo de jucá (Libidibia ferrea)." Research, Society and Development 9, no. 7 (June 20, 2020): e945975224. http://dx.doi.org/10.33448/rsd-v9i7.5224.

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O jucá é uma planta comum no nordeste brasileiro, tem sua capacidade antioxidante conhecida e poder terapêutico comprovado. Porém, existem poucas informações sobre sua utilização como bioaditivo antioxidante em óleo de soja. Desta forma, investigou-se a eficácia antioxidante dos extratos aquosos e hidroalcoólicos do jucá, por meio das análises in vitro (teor de compostos fenólicos totais, atividade antioxidante pelos métodos sequestrador de radical livre - DPPH e por redutor de ferro - FRAP), e in vivo (índice de peróxido do óleo de soja aditivado, monitorado por 90 dias). Os extratos hidroalcoólicos do jucá apresentaram maior estabilidade oxidativa que os extratos aquosos. Os extratos hidroalcoólicos do jucá apresentaram elevados teores de compostos fenólicos (166,59 mgEAG/g de fruto e 179,55 mgEAG/g de casca do caule), e elevadas atividades antioxidantes pelos métodos de DPPH e FRAP, ao final dos 90 dias. As investigações in vivo indicaram que a formulação de extrato hidroalcoólico com 0,85% do fruto e 0,85% da casca do caule apresentaram um maior efeito protetor contra o aumento do índice de peróxido no óleo de soja, mostrando que a utilização simultânea dos aditivos apresenta efeito antioxidante sinérgico. Portanto, os extratos hidroalcoólicos de jucá podem ser utilizados como bioaditivo antioxidante em óleo de soja.

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Ferreira, Diego Q., Thamara O. Ferraz, Raquel S. Araújo, Rodrigo Alves Souza Cruz, Caio Pinho Fernandes, Gisele C. Souza, Brenda L. S. Ortiz, et al. "Libidibia ferrea (jucá), a Traditional Anti-Inflammatory: A Study of Acute Toxicity in Adult and Embryos Zebrafish (Danio rerio)." Pharmaceuticals 12, no. 4 (November 30, 2019): 175. http://dx.doi.org/10.3390/ph12040175.

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The plant species Libidibia ferrea (Mart. ex Tul.) LP Queiroz var. ferrea basionym of Caesalpinia ferrea (Mart. ex Tul.) is used in various regions of Brazil in folk medicine in the treatment of several health problems, especially in acute and chronic inflammatory processes. Most of the preparations employed are alcoholic. Therefore, this study aimed to evaluate the acute toxicity of the hydroethanolic extract of fruits of Libidibia ferrea (EHEFLf) in zebrafish, emphasizing the possible changes in the organic-cellular level of the gills, liver, kidneys, and intestine and on embryos. The result obtained by LC-M/MS from EHEFLf indicated a high concentration of possible polyhydroxylated substances. EHEFLf, at a dose of 2 g/kg orally, produced non-significant alterations of the analyzed organs. However, for embryos, the treatment with different concentrations demonstrated heart toxicity that was concentration-dependent. There is no evidence of a correlation of the observed effects with the phytochemical composition, and considering the species of animal used, it can be suggested that the oral use of L. ferrea hydroethanolic extract has an acceptable degree of safety for use as an oral medicinal product. and embryo results have shown significant affinity to the heart; however, it is perceived to be related to the concentrations used.

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Brasileiro de Vasconcelos, Carlos Fernando, Hélida Maria de Lima Maranhão, João Henrique da Costa-Silva, Cristiano Ribeiro de Lima, Jacinto da Costa Silva Neto, Sérgio Faloni de Andrade, Fabiano Ferreira, and Almir Gonçalves Wanderley. "Chronic toxicological study of the stem bark aqueous extract from Libidibia ferrea Mart. ex Tul." Biomedical and Biopharmaceutical Research Journal 17, no. 2 (September 2020): 1–17. http://dx.doi.org/10.19277/bbr.17.2.238.

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Libidibia ferrea Martius Ext Tul. has been used in popular medicine to treat a wide range of diseases such as diabetes, gastric ulcer, and cancer; however, no preclinical safety study of the stem bark aqueous extract has been identified. We studied the chronic toxicity of an aqueous extract of L. ferrea stem bark in mice with oral doses of 300 and 1500 mg/ kg/day for 12 weeks. As indicators of toxicity, body weight, as well as food and water intake, were evaluated. Analysis of biochemical and haematological parameters and histopathologic studies were also conducted. The groups treated with L. ferrea presented significant loss in body weight gain and an irregular pattern of consumption of water and feed. There was also a marked increase in the white blood cell count and an important reduction in the levels of aspartate aminotransferase, amylase, and lactate dehydrogenase. Histopathological analysis revealed the presence of inflammation in the small intestine and kidneys. The data set indicates that repeated administration of the aqueous extract of Libidibia ferrea stem bark is not completely safe in Swiss mice as evidenced by impairment of mice growth, development of nephro-enterotoxicity, which consequently leads to alteration of some biochemical, and hematological parameters.

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Drozino, Ricardo Nascimento, Maria José Pastre Zulin, Lucas Casagrande, and Andréia Vieira Pereira. "Mini revisão: BIOATIVOS DE Libidibia ferrea E SUAS AÇÕES EM ODONTOLOGIA." Arquivos do Museu Dinâmico Interdisciplinar 21, no. 1 (September 12, 2017): 39–47. http://dx.doi.org/10.4025/arqmudi.v21i1.37807.

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Compostos bioativos de plantas são de extrema importância para a produção de novos medicamentos, principalmente quando se trata da medicina complementar. Em tratamentos odontológicos, dores e incômodos são recorrentes, levando o paciente, muitas vezes a interromperem ou pararem o tratamento sem o conhecimento de seu dentista. Dessa forma, bioativos e fitoterápicos, como os de Libidibia ferrea, que apresentam eficiência no tratamento de enfermidades bucais e ação contra microrganismos patógenos, são uma alternativa para tratamentos odontológicos mais eficientes. O extrato de L. ferrea favorece o interesse científico pela indústria odontológica e farmacêutica, por apresentar atividades analgésicas, anti-inflamatórias e de ação anti-bacteriana contra patógenos da cavidade bucal. A ineficiência de alguns compostos sintéticos, o alto custo na produção de alopáticos e o interesse da população por tratamentos menos agressivos favorecem a pesquisa científica nesse ramo. Por hora, mesmo com a comprovação da eficiência e da produção de medicamentos baseada em compostos bioativos de L. ferrea, seu uso é um tanto restrito em odontologia, um desafio a ainda ser explorado pela comunidade científica.

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Ramos, Luan Victor Resque, Anísia Sofia Mota Barros, and Maria Fani Dolabela. "Análise in silico de metabólitos ativos isolados de Libidibia ferrea Martius." Research, Society and Development 9, no. 12 (December 13, 2020): e7991210910. http://dx.doi.org/10.33448/rsd-v9i12.10910.

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O presente trabalho realizou estudos in silico para predição das atividades farmacocinéticas, físico-químicas, toxicológicas e biológicas de metabólitos isolados de Libidibia ferrea Martius, planta utilizada popularmente para o tratamento de inflamações e lesões, como antidiabética, antimicrobiana, antifúngica e antileishmaniose. As comparações foram realizadas através dos programas: chemsketch, mcule property calculator, preadmet, protox e pass online. Os resultados revelaram que apenas as moléculas lupenona e o trans-farnesol apresentaram absorção intestinal acima de 90%. Os metabólitos ácido gálico, catequina, metil-galato, quercetina e trans-farnesol seguem a regra de lipinsk em todos os seus parâmetros pré-condicionados. No que se refere a inibição enzimática, cada uma das moléculas do estudo demonstrou inibição direcionada a pelo menos duas enzimas da CYP. A lupenona foi a única molécula que se apresentou ativa contra o protozoário leishmania, além de ser promissora contra neoplasias e inflamação. A catequina e quercetina demonstraram resultados positivos no que tange a atividade antioxidante, e a maioria das substâncias do estudo em questão apresentaram capacidade de proteção mucomembranosa. Nenhuma substância demonstrou embriotoxicidade ou teratogênese, mas todas as moléculas demonstraram possuir certo nível de toxicidade em outros parâmetros de análise. Em termos farmacocinético, toxicológico e biológico, as moléculas pauferrol A, B e C foram as menos promissoras, enquanto que a lupenona, catequina e quercetina apresentaram os melhores resultados.

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Luna, M. S. M., R. A. de Paula, R. M. P. Brandão Costa, J. V. dos Anjos, M. V. da Silva, and M. T. S. Correia. "Bioprospection of Libidibia ferrea var. ferrea: Phytochemical properties and antibacterial activity." South African Journal of Botany 130 (May 2020): 103–8. http://dx.doi.org/10.1016/j.sajb.2019.12.013.

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Grisi, Cristiani Viegas Brandão, Angela Maria Tribuzy de Magalhães Cordeiro, Andressa Samara de Carvalho Ferreira, Agdylannah Felix Vieira, Ana Paula Trindade Rocha, and Gilmar Trindade de Araújo. "Nutritional, anti-nutritional and technological functionality of flour from Libidibia ferrea." Revista Principia - Divulgação Científica e Tecnológica do IFPB 1, no. 53 (February 3, 2021): 206. http://dx.doi.org/10.18265/1517-0306a2020v1n53p206-217.

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Marreiro, RO, MFCL Bandeira, MC Almeida, CN Coelho, GN Venâncio, and NCO Conde. "Avaliação da citotoxicidade de um enxaguatório bucal contendo extrato de Libidibia férrea." Pesquisa Brasileira em Odontopediatria e Clínica Integrada 14, Supl.3 (2014): 34–42. http://dx.doi.org/10.4034/pboci.2014.14s3.04.

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Leandro, Cícero dos Santos, José Weverton Almeida Bezerra, Maria Daniele Pereira Rodrigues, Ana Karolina Fernandes Silva, Danúbio Lopes da Silva, Marcos Aurelio Figueiredo dos Santos, Karina Vieiralves Linhares, et al. "Phenolic Composition and Allelopathy of Libidibia ferrea Mart. ex Tul. in Weeds." Journal of Agricultural Science 11, no. 2 (January 15, 2019): 109. http://dx.doi.org/10.5539/jas.v11n2p109.

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Considering the need to produce effective bioherbicides to control weeds and thus reduce the contamination of environments through the use of agrochemicals in control of these plants, the scientific community has been studying the allelopathic activity of several species of Caatinga, once studies indicate that some species of this biome presentind to have activity allelopathic about other plants. On this, the present study aimed to evaluate the allelopathic potential and phenolic composition of extracts of Libidibia ferrea Mart. ex Tul. on seed germination and seedling development of Calotropis procera (Aiton) WT Aiton. and Cenchrus echinatus L. For the allelopathy test, leaf, bark and root extracts, both hot (100 °C) and cold (25 °C), were used, followed by a control group (distilled H2O). Phytochemical prospecting was performed by High Performance Liquid Chromatography (HPLC). The results showed that the hot L. ferrea bark extract has allelopathic activity on C. procera and C. echinatus, which was observed in all parameters analyzed. The phytochemical results showed that L. ferrea extracts present several phenolic compounds which are possibly responsible for the results observed against the two weed species studied, with standing out Gallic acid, Catechin, Caffeic acid, Ellagic acid, and Quercetin. It is therefore necessary to isolate these compounds in view of a potential future use for L. ferrea extracts in the production of a bioherbicide.

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Pedrosa, Tatiana do Nascimento, Aline Oliveira Barros, Jéssica Rodrigues Nogueira, Andréa Costa Fruet, Isis Costa Rodrigues, Danielle Queiroz Calcagno, Marilia de Arruda Cardoso Smith, et al. "Anti-wrinkle and anti-whitening effects of jucá (Libidibia ferrea Mart.) extracts." Archives of Dermatological Research 308, no. 9 (September 13, 2016): 643–54. http://dx.doi.org/10.1007/s00403-016-1685-0.

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Venâncio, Gisely Naura, Wanderleia Monteiro de Souza, Fábio Correia Sampaio, Maria Fulgência Costa Lima Bandeira, Marne Carvalho de Vasconcellos, Tatiane Pereira de Souza, Carina Toda, and Nikeila Chacon de Oliveira Conde. "CYTOTOXICITY AND ANTIMICROBIAL ACTIVITY OF MOUTHWASH OBTAINED FROM THE EXTRACT OF LIBIDIBIA FERREA MART / CITOTOXICIDADE E ATIVIDADE ANTIMICROBIANA DE ENXAGUATÓRIO BUCAL OBTIDO DO EXTRATO DE LIBIDIBIA FERREA MART." Brazilian Journal of Development 6, no. 9 (2020): 69828–41. http://dx.doi.org/10.34117/bjdv6n9-433.

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Souza, Amanda Luzia Moreira de, Anselmo Junio Pedroso Matos, Wanderleia Monteiro de Souza, Tatiane Pereira de Souza, Gisely Naura Venâncio, Maria Fulgência Costa Lima Bandeira, Carina Toda, Ana Regina Casaroto Moreschi, and Nikeila Chacon de Oliveira Conde. "Antimicrobial activity and quality control of a formulation based on Libidibia ferrea after aging." Research, Society and Development 10, no. 10 (August 16, 2021): e487101018996. http://dx.doi.org/10.33448/rsd-v10i10.18996.

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This study aimed to evaluate in vitro the pharmacological stability of a herbal mouthwash based on Libidibia ferrea extract after aging, establishing its organoleptic and microbiological characteristics. It is a 7.5% hydroalcoholic extract from Libidibia ferrea pods, using the reflux decoction technique, and spray dried. The stability, pH, sedimentation, density, and antimicrobial activity tests of the mouthwash were performed with the solutions stored after 24 months. Contaminant control was carried out by determining the total number of microorganisms and researching Salmonella sp., Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The formulation's antimicrobial activity against microorganisms present in the dental biofilm was analyzed: Streptococcus mutans, Streptococcus salivarius, Lactobacillus casei, and Candida albicans., The data were analyzed using the Tukey test to assess pH and density, and the other results were described using descriptive statistics., The color observed in the organoleptic characters, was “Ceramics”, with a fluid/serous consistency, shiny appearance, and a strong minty, woody odor. In the sedimentation phase, the separation was observed, and the pH and density analyzes showed a mean value of 5.46 and 1.029 g/cm3, respectively. The contaminant assessment test was negative for all microorganisms surveyed, within 24 months. The mouthwash showed bactericidal/fungicidal activity against all the microorganisms tested at all concentrations for S. mutans and C. albicans. At concentrations 0.5 mg/ml for S. salivarius and 0.6 mg/ml for L casei. It was concluded that after 24 months, the formulation of the mouthwash based on L. ferrea, its initial characteristics remained stable except for the homogeneity and pH of the solution.

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Gasson, Peter, Kate Warner, and Gwilym Lewis. "Wood Anatomy of Caesalpinia S.S., Coulteria, Erythrostemon, Guilandina, Libidibia, Mezoneuron, Poincianella, Pomaria and Tara (Leguminosae, Caesalpinioideae, Caesalpinieae)." IAWA Journal 30, no. 3 (2009): 247–76. http://dx.doi.org/10.1163/22941932-90000218.

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Caesalpinia s.l. traditionally comprised c. 140 species in the New and Old World tropics, and contained a maximum of 25 generic synonyms. The genus in its broadest sense has been shown to be polyphyletic in molecular studies, and most species have now been assigned to reinstated segregate genera: Caesalpinia s.s. (c. 25 spp.), Coulteria (10 spp.), Erythrostemon (13 spp.), Guilandina (c. 7 spp.), Libidibia (8 spp.), Mezoneuron (c. 26 spp.), Poincianella (c. 35 spp.), Pomaria (16 spp.) and Tara (3 spp.). About 15 Asian taxa remain unassigned pending more data, especially DNA sequences. In this paper we describe the wood anatomy of these nine segregate genera, outlining the features that consistently help define some of them. We have examined the wood of 27 species representing all the woody segregate genera and found wood descriptions of three more species in the literature. Most species lack well defined growth rings, vessels are solitary and in radial multiples, intervessel pitting is alternate and vestured, fibres are mainly non-septate, axial parenchyma is aliform to confluent and irregularly storied, and the rays are mainly 1–2-seriate, mostly non-storied, and of varying height. Prismatic crystals are in chambered axial parenchyma cells in all except Erythrostemon gilliesii (Hook.) Link, and in ray cells in many species. Libidibia is well defined, with storied axial parenchyma, narrow short storied homocellular rays and lacking crystals in ray cells. Tara is also well defined with non-storied heterocellular rays and some ray cells containing crystals. The other genera are less consistent in wood characters. In Caesalpinia s.s. the rays are not storied, and most species lack crystals in ray cells. Coulteria has some species with storied rays and all have homocellular rays and crystals in ray cells. Poincianella is particularly poorly defined from a wood anatomical point of view, perhaps indicating that it can be further segregated. A few Poincianella species have septate fibres, which are otherwise seen only in Libidibia corymbosa. Mezoneuron has non-storied, heterocellular rays. The two species of Guilandina we examined have wide vessels and heterocellular rays containing crystals. Only two species of Erythrostemon were examined and E. gilliesii was unusual in having ring porous wood and very wide rays (but the sample was cultivated at Kew, and we do not know its porosity in its native range). Caesalpinia decapetala (Roth) Alston (originally described as Reichardia decapetala Roth) and Caesalpinia sappan L. from the Old World have not been reassigned to a segregate genus. Pomaria is mainly herbaceous and we have included some information on it.

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Soares, LuizA L., MagdaR A. Ferreira, MônicaT M. Fernandes, WlianaA V. da Silva, IsabelleC F. Bezerra, TatianeP de Souza, and MariaF Pimentel. "Chromatographic and spectrophotometric analysis of phenolic compounds from fruits of Libidibia ferrea Martius." Pharmacognosy Magazine 12, no. 46 (2016): 285. http://dx.doi.org/10.4103/0973-1296.182165.

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Jozala, Angela F., Julia R. Santos, Gabriela R. Santos, Fabia J. M. Viroel, Thaisa B. Pickler, Carolina Alves Santos, Marcia A. Rebelo, et al. "Libidibia ferrea loaded in bacterial nanocellulose: evaluation of antimicrobial activity and wound care." Brazilian Journal of Development 6, no. 2 (2020): 6212–26. http://dx.doi.org/10.34117/bjdv6n2-066.

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Queiroz, L. P. "New combinations in Libidibia (DC.) Schltdl. and Poincianella Britton & Rose (Leguminosae, Caesalpinioideae)." Neodiversity 5, no. 1 (December 31, 2010): 11–12. http://dx.doi.org/10.13102/neod.51.3.

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Alves, Rafael Mateus, Monalisa Alves Diniz da Silva, Joyce Naiara da Silva, Rosemeire Santos Costa, Bruna Kaline de Lima Santos, and Edjane Da Silva Lima. "Efeito alelopático de Libidibia ferrea Mart. sobre o vigor das sementes de feijão-caupi." Revista Verde de Agroecologia e Desenvolvimento Sustentável 14, no. 3 (November 7, 2019): 476–79. http://dx.doi.org/10.18378/rvads.v14i3.5974.

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O feijão-caupi é uma das principais culturas de importância para a região Nordeste, sendo cultivada em áreas da Caatinga, considerando isso é necessário o estudo da interação entre culturas agrícolas e espécies florestais nesse Bioma. Logo, o presente trabalho teve como objetivo avaliar uma possível influência alelopática de folhas secas em processo de decomposição de Libidibia ferrea Mart. sobre o desenvolvimento de plântulas de feijão-caupi, cv. Canapu. As folhas da espécie florestal foram coletadas no horário da manhã, e secas à 40 ºC, durante 24 horas em estufa, seguidamente foram manualmente fragmentadas e adicionadas em areia formando o substrato, adotou-se as seguinte proporções de folhas secas e areia: 1:0 (controle); 1:1/2; 1:1 e 1:2 (v:v). Os substratos ficaram decompondo por 15; 30; 45 e 60 dias, o tratamento controle sem decomposição, assim subsequentemente realizou-se a semeadura das sementes de feijão-caupi. Foi avaliado a altura de plântula e comprimento da raiz, massa seca da parte aérea, do sistema radicular e total de plântulas normais. Foi utilizado o delineamento inteiramente casualizado em esquema fatorial 4x5 (proporções de areia: folhas secas x períodos de decomposição). O período de 30 dias de decomposição ocasiona uma redução no comprimento da parte aérea, na massa seca da parte aérea, do sistema radicular e total das plântulas, o aumento das proporções de folhas secas de pau ferro afeta a massa seca da parte aérea e total de plântulas. Diante disso, o cultivo de feijão-caupi, cv. Canapu, e pau ferro em um sistema agroflorestal não é viável.

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Guerra, Andreza Conceição Véras de Aguiar, Luiz Alberto Lira Soares, Magda Rhayanny Assunção Ferreira, Aurigena Antunes de Araújo, Hugo Alexandre de Oliveira Rocha, Juliana Silva de Medeiros, Rômulo dos Santos Cavalcante, and Raimundo Fernandes de Araújo Júnior. "Libidibia ferrea presents antiproliferative, apoptotic and antioxidant effects in a colorectal cancer cell line." Biomedicine & Pharmacotherapy 92 (August 2017): 696–706. http://dx.doi.org/10.1016/j.biopha.2017.05.123.

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Longui, Eduardo Luiz, Juliana Aparecida Moureira, Daniel Romeu Lombardi, Francides Gomes da Silva Júnior, and Edenise Segala Alves. "Potential use of Libidibia ferrea and Poincianella pluviosa woods for bows of string instruments." European Journal of Wood and Wood Products 76, no. 1 (April 21, 2017): 357–68. http://dx.doi.org/10.1007/s00107-017-1187-6.

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da Silva Maia-Neto, Luiz, Ademir Amaral, Luciano Rodolfo Ferreira de Lucena, Simey de Souza Leão Pereira Magnata, Edvane Borges da Silva, André Maciel Netto, Antônio Fernando Morais de Oliveira, and Ivone Antônia de Souza. "Gamma irradiation for enhancing active chemical compounds in leaf extracts of Libidibia ferrea (Leguminosae)." Applied Radiation and Isotopes 166 (December 2020): 109306. http://dx.doi.org/10.1016/j.apradiso.2020.109306.

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Marreiro, Raquel de Oliveira, Wanderleia Monteiro de Souza, Tatiana Nayara Libório Kimura, Tatiane Pereira de Souza, Maria Fulgência Costa Lima Bandeira, Carina Toda, Gisely Naura Venâncio, and Nikeila Chacon de Oliveira Conde. "Avaliação da biocompatibilidade do enxaguatório de Libidibia ferrea em mucosa bucal de ratos - estudo piloto / Evaluation of the biocompatibility of the Libidibia ferrea mouthwash in the oral mucosa of rats – a pilot study." Brazilian Journal of Development 7, no. 6 (June 19, 2021): 60912–27. http://dx.doi.org/10.34117/bjdv7n6-457.

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Carvalho, Sara Monaliza Costa, Salvador Barros Torres, Clarisse Pereira Benedito, Narjara Walessa Nogueira, Antonia Adailha Torres Souza, and Maria Lilia de Souza Neta. "Viability of Libidibia ferrea (Mart. ex Tul.) L.P. Queiroz var. ferrea) seeds by tetrazolium test." Journal of Seed Science 39, no. 1 (March 2017): 7–12. http://dx.doi.org/10.1590/2317-1545v39n1163784.

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Abstract: Rapid tests have been essential to evaluate the physiological potential of seeds and the tetrazolium test is one of those which have been used by seed companies. The objective of the study was to establish the procedure for the tetrazolium test in Libidibia ferrea (Mart. Ex Tul.) L.P. Queiroz var. ferrea seeds. For this, three tetrazolium solution concentrations (0.05, 0.075 and 0.1%) and three staining periods (1, 3 and 6 hours) at temperatures of 35 to 40 °C were tested. The seeds were also evaluated by the germination test, whose result was compared with viability by the tetrazolium test. The experimental design was completely randomized in a factorial design 3 x 3 + 1 (three concentrations x three periods + a control = germination test) for each temperature. Viable seeds in the tetrazolium test were compared by Tukey’s test (p ≤ 0.05), while the comparison between the viable seeds with germination test was carried out by Dunnett’s test (p ≤ 0.05). It is recommended that the tetrazolium test for L. ferrea is carried out at a concentration of 0.05% for three-hour staining under 35 °C or 40 °C.

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COMANDOLLI-WYREPKOWSKI, Claudia Dantas, Bruno Bezerra JENSEN, Iryna GRAFOVA, Pierre Alexandre dos SANTOS, Angela Maria Comapa BARROS, Fabiane Veloso SOARES, José Fernando Marques BARCELLOS, Aline Fagundes da SILVA, Andriy GRAFOV, and Antonia Maria Ramos FRANCO. "Antileishmanial activity of extracts from Libidibia ferrea: development of in vitro and in vivo tests." Acta Amazonica 47, no. 4 (December 2017): 331–40. http://dx.doi.org/10.1590/1809-4392201700871.

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ABSTRACT Treatment of cutaneous leishmaniasis (CL) is difficult due to the scarce number of drugs able to eliminate completely the intracellular form of the parasite. In the present study, the aim was to evaluate: i) phytochemical properties of extracts from Libidibia ferrea; ii) antileishmanial activity of extracts from L. ferrea against promastigotes and amastigotes of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) guyanensis; iii) the effects of topical treatment using hydrogel containing active extract of L. ferrea on golden hamsters infected with L. (L.) amazonensis. Extracts from leaves, branches and fruits of L. ferrea were obtained with hexane and methanol and were tested by in vitro assays in promastigotes and murine macrophages J774 experimentally infected with amastigotes of Leishmania. Groups of hamsters with CL received topical treatment with a formulation of extract (10%) hydrogels, 50 mg.day-1 for 40 days. In vitro activity of FrMeOH (methanolic extract from fruits without seeds) resulted in significant reduction of viable promastigotes of L. (L.) amazonensis (IC50 of 15.4 µg.mL-1) and demonstrated inhibition potential of amastigote forms of L. (L.) amazonensis and L. (V.) guyanensis and low cytotoxicity in macrophages. The overall data of topical treatment with extract hydrogels (GelFrMeOH) showed that lesion sizes were significantly reduced (42.78%), with low parasite burden by RT-qPCR and culture analysis by microscopy examination, and with histopathological findings such as lower inflammatory cell infiltration 40 days after treatment. Chemical analysis demonstrated FrMeOH contains high levels of phenolic compounds. The results indicate a possible alternative therapy for CL using phytotherapics.

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Lopes, Rosineide S., Luciana G. Oliveira, Antonio F. Costa, Maria T. S. Correia, Elza A. Luna-Alves Lima, and Vera L. M. Lima. "Efficacy of Libidibia ferrea var. ferrea and Agave sisalana Extracts against Dactylopius opuntiae (Hemiptera: Coccoidea)." Journal of Agricultural Science 10, no. 4 (March 5, 2018): 255. http://dx.doi.org/10.5539/jas.v10n4p255.

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The carmine cochineal (Dactylopius opuntiae) is an insect-plague of Opuntia ficus-indica palm crops, causing losses in the production of the vegetable used as forage for the Brazilian semiarid animals. The objective of this work was to analyze the efficacy of plant extracts, insecticides and their combination in the control of D. opuntiae. Leaf and pod extracts of Libidibia ferrea var. ferrea, Agave sisalana leaf at concentrations 10, 25, 50, 100 and 200 mg/mL, and insecticides (chlorpyrifos, acetamiprid, thiamethoxam and lamba-cyhalothrin) at concentrations minimum, median and maximum; were applied on cladodes infested by D. opuntiae. After 10 days of treatment, the percentages of mortality and LC50 (concentration to kill 50% of cochineal) were obtained on the stages of nymphs II and adult females. The association between the LC50 of the plant extracts with the insecticides on the cochineal it was tested. The results showed that L. ferrea extracts were more effective against cochineal, causing the 81% of nymphal II mortality (LC50: 20 to 160 mg/mL) and 97% of adult females (LC50: 43 to 50 mg/mL), whereas the extracts of A. sisalana only controlled adult females, causing the mortality from 51 to 97% (LC50: 17 to 46 mg/mL). The insecticide chlorpyrifos was the most efficient on nymphs and adult females cochineal (LC50: 0,084 mL/L). The combination of this insecticide with the extracts promoted a percentage of mortality above 90%. The extracts presented insecticidal potential on D. opuntiae and can be tested isolated or in combination with insecticides in control of cochineal.

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Lima e Souza, Larissa Alves de, Keily da Silva Melo, Letícia da Silva Soares Gomes, Tatiane Pereira de Souza, Maria Fulgência Costa Lima Bandeira, Carina Toda, and Nikeila Chacon de Oliveira Conde. "Controle de qualidade de uma formulação de enxaguatório bucal à base de Libidibia Ferrea L." Brazilian Journal of Development 6, no. 7 (2020): 47236–46. http://dx.doi.org/10.34117/bjdv6n7-383.

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MELO, LUCIANA ALEIXO DOS SANTOS DE, MARIA FULGêNCIA COSTA LIMA BANDEIRA, LILIANE LISBOA DA COSTA SANTOS, ANA PAULA NEGREIROS NUNES ALVES, ANTôNIO ERNANDO CARLOS FERREIRA JUNIOR, CARINA TODA, and NIKEILA CHACON OLIVEIRA CONDE. "CICATRICIAL EFFECT OF LIBIDIBIA FERREA ORABASE OINTMENT ON ULCERS IN THE ORAL CAVITY OF RATS." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 130, no. 3 (September 2020): e281-e282. http://dx.doi.org/10.1016/j.oooo.2020.04.778.

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Morais, Elís Regina Costa de Morais, Henrique Campos Nogueira, Samantha Joyce Bezerra Faustino, and Hiara Ruth Silva Câmara Gaudêncio. "Avaliação de substrato de macrófita aquática para o crescimento de mudas de Jucá (Libidibia ferrea)." Research, Society and Development 9, no. 8 (July 9, 2020): e399985869. http://dx.doi.org/10.33448/rsd-v9i8.5869.

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Sabe-se que a ação humana, nas últimas décadas, vem causando sérias consequências ao meio ambiente, possivelmente porque o sistema econômico vigente demanda uma produção em larga escala e, consequentemente, um maior uso dos recursos naturais. Nesse contexto, este estudo objetivou avaliar o crescimento inicial de Jucá (Libidibia ferrea) em função do composto orgânico de macrófita aquática (E. crassipes). Os tratamentos foram distribuídos em blocos casualizados com três repetições, sendo as unidades experimentais constituídas por vasos com 2 dm3 de solo e as diferentes combinações do composto orgânico e solo, foram compostos os seguintes tratamentos: T1 = solo; T2 = 95% de solo + 5% do composto; T3 = 90% de solo + 10% do composto; T4 = 80% de solo + 20% do composto e T5 = 70% de solo + 30% do composto. Dez dias após a emergência das plantas, foi realizado o transplantio, e durante o período de 60 dias foram realizadas seis leituras de altura de planta e diâmetro de caule para avaliação do crescimento, sendo a primeira dez dias após o transplantio e as seguintes, também, em intervalo de dez. A TCA e TCR, tanto para altura de planta como para diâmetro do caule foram semelhantes em todos os tratamentos, ressaltando que para T4 e T5 observou-se maiores alturas e em T3 a TCR do diâmetro apresentou crescimento mais uniforme.

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Santos, Emanuela Lima dos, Brena Coutinho Muniz, Beathriz Godoy Vilela Barbosa, Marcia Maria Camargo Morais, Francineyde Alves da Silva, and Fábio Sérgio Barbosa da Silva. "Is AMF inoculation an alternative to maximize the in vitro antibacterial activity of Libidibia ferrea extracts?" Research, Society and Development 10, no. 1 (January 4, 2021): e10010111435. http://dx.doi.org/10.33448/rsd-v10i1.11435.

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Arbuscular mycorrhizal fungi (AMF) are known to provide plant species with several benefits, such as an increased production of bioactive compounds. However, it is yet to be defined whether extracts of mycorrhizal plants are more efficient in vitro antibacterial actions when compared to non-mycorrhizal plants. We tested the hypothesis of whether or not, methanolic extracts of Libidibia ferrea fruits, from plants established in the field and inoculated with AMF, have higher antibacterial action when inoculated with Acaulospora longula, Claroideoglomus etunicatum or Gigaspora albida. In addition, native L. ferrea fruits collected from the Caatinga area were also tested. The extracts of L. ferrea fruits inoculated with A. longula had higher in vitro antibacterial action in relation to the extracts of fruits from non-inoculated plants (p <0.05) thus characterizing the first record of different antibacterial actions of plant extracts due to inoculation with AMF. The extracts of L. ferrea fruits inoculated with A. longula were more efficient in inhibiting growth of Gram-negative bacteria. The zone diameters of inhibition ranged from 2.48 % to 7.56 % larger than the zones of the non-inoculated L. ferrea fruit extracts. The inoculation of L. ferrea with AMF may represent an alternative way of producing fruits with different antibacterial activity.

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dos Santos, Emanuela L., Wliana A. V. da Silva, Magda R. A. Ferreira, Luiz Alberto Soares, Everardo V. de Sá Barretto Sampaio, Francineyde A. da Silva, and Fábio S. B. da Silva. "Acaulospora longula Increases the Content of Phenolic Compounds and Antioxidant Activity in Fruits of Libidibia ferrea." Open Microbiology Journal 14, no. 1 (June 29, 2020): 132–39. http://dx.doi.org/10.2174/1874285802014010132.

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Background: Several countries have made an association that how conventional and traditional medicines support the rational use of medicinal plants in different treatments. Brazil has stimulated the cultivation of and the development of the studies of Libidibia ferrea, a plant with medicinal properties, which are provided by the presence of bioactive compounds in its several parts, such as fruits. The synthesis of these biomolecules may increase with Arbuscular Mycorrhizal Fungi (AMF) inoculation. However, there have been no previous reports about the optimization in the production of biomolecules in the fruits of mycorrhizal L. ferrea. Objective: The aim of this study was to define the potential advantages of inoculation with AMF by increasing the production of biomolecules and antioxidant activity in fruits of mycorrhizal L. ferrea. Methods: The phytochemical and mycorrhizal analyses occurred after 32 months of transplanting to the field and the plants were inoculated or not with Acaulospora longula, Claroideoglomus etunicatum and Gigaspora albida and then by transplanting the seedlings to the field. Results: Compared to those from the control treatment, the concentration of phenols and tannins in the fruits of L. ferrea inoculated with A. longula increased 26.4% and 39.8% (p <0.05), respectively. The fruits also had higher antioxidant activity. In contrast, the concentration of phosphorus in the fruits of L. ferrea inoculated with A. longula and C. etunicatum was not incresead. Because the concentration of phosphorus in fruits was verified in this study. Conclusion: Mycorrhization increased the concentration of biocompounds and antioxidant activity in the fruits of L. ferrea, which is of great interest to the herbal medicine industry.

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Dias, A. M. A., A. Rey-Rico, R. A. Oliveira, S. Marceneiro, C. Alvarez-Lorenzo, A. Concheiro, R. N. C. Júnior, M. E. M. Braga, and H. C. de Sousa. "Wound dressings loaded with an anti-inflammatory jucá (Libidibia ferrea) extract using supercritical carbon dioxide technology." Journal of Supercritical Fluids 74 (February 2013): 34–45. http://dx.doi.org/10.1016/j.supflu.2012.12.007.

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Passos, Manuela Ribeiro, Rafael Silva Almeida, Brenda Oliveira Lima, Jeisa Zielle de Souza Rodrigues, Nayara Silva de Macêdo Neres, Louise Soares Pita, Patrick D'Orleans Farias Marinho, et al. "Anticariogenic activities of Libidibia ferrea, gallic acid and ethyl gallate against Streptococcus mutans in biofilm model." Journal of Ethnopharmacology 274 (June 2021): 114059. http://dx.doi.org/10.1016/j.jep.2021.114059.

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Magda Rhayanny, Assuncao Ferreira, and Alberto Lira Soares Luiz. "Libidibia ferrea (Mart. ex Tul.) L. P. Queiroz: A review of the biological activities and phytochemical composition." Journal of Medicinal Plants Research 9, no. 5 (February 3, 2015): 140–50. http://dx.doi.org/10.5897/jmpr2014.5706.

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Lopes, Rosineide S., Mônica Cristina B. Martins, Luciana G. de Oliveira, Antonio F. da Costa, Venézio F. dos Santos, Maria Tereza S. Correia, Nicácio H. da Silva, Auristela C. de Albuquerque, Elza Áurea Luna-Alves Lima, and Vera Lúcia M. Lima. "Termiticidal Activity of Libidibia ferrea var. ferrea and of the Association With Isaria spp. Against Nasutitermes corniger." Journal of Agricultural Science 12, no. 1 (December 15, 2019): 159. http://dx.doi.org/10.5539/jas.v12n1p159.

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Nasutitermes corniger (Motschulsky) is an urban termite pest that is controlled by chemical applications. We investigated the effect of the association of Isaria farinosa (Holm: Fries) Fries, I. fumosorosea (Wize) Brown & Smith, and I. javanica (Frieder & Bally) Samson & Hywell-Jones with the extracts of Libidibia ferrea var. ferrea (Mart. Ex Tul.) L. P. Queiroz in the control of N. corniger. The following experiments were performed: the toxicity of aqueous and methanolic extracts on the biological aspects of fungi, action of extracts on workers and soldiers, and fungus-extract combination on workers of termite. The aqueous extracts of the leaves and pods of L. ferrea var. ferrrea were more efficient than the methanol extracts, demonstrating termiticide activity at 10, 25, 50, 100, and 200 mg mL-1, with 100% worker mortality after the third and fourth days and 100% soldier mortality by the third through sixth day. Lethal concentrations (LC50) varied from 0.624 to 0.710 mg mL-1 for workers and from 0.146 to 1.410 mg mL-1 for soldiers. The extracts were compatible with the fungal strains at the lowest concentrations. Associations of the extracts with I. farinosa ESALQ1355 demonstrated efficient control of termite workers. The results demonstrate that L. ferrea var. ferrrea extracts, either alone or in association with I. farinosa ESALQ1355, functioned in the in vitro control of N. corniger, representing a viable alternative to be further tested in controlling those termites in urban areas.

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Prazeres, Lady D. K. T., Ticiana P. Aragão, Samara A. Brito, Cynthia L. F. Almeida, Amanda D. Silva, Mirella M. F. de Paula, Juliane S. Farias, et al. "Antioxidant and Antiulcerogenic Activity of the Dry Extract of Pods of Libidibia ferrea Mart. ex Tul. (Fabaceae)." Oxidative Medicine and Cellular Longevity 2019 (November 20, 2019): 1–23. http://dx.doi.org/10.1155/2019/1983137.

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Ethnomedicinal studies in the Amazon community and in the Northeast region of Brazil highlight the use of Libidibia ferrea fruits for the treatment of gastric problems. However, there are no data in the literature of this pharmacological activity. Thus, the aim of this paper is to provide a scientific basis for the use of the dry extract of L. ferrea pods (DELfp) for the treatment of peptic ulcers. Phytochemical characterization was performed by HPLC/MS. In vitro antioxidant activity was assessed using DPPH, ABTS, phosphomolybdenum, and superoxide radical scavenging activity. The gastroprotective activity, the ability to stimulate mucus production, the antisecretory activity, and the influence of -SH and NO compounds on the antiulcerogenic activity of DELfp were evaluated. The healing activity was determined by the acetic acid-induced chronic ulcer model. Anti-Helicobacter pylori activity was investigated. HPLC/MS results identified the presence of phenolic compounds, gallic acid and ellagic acid, in DELfp. The extract showed antioxidant activity in vitro. In ulcers induced by absolute ethanol and acidified ethanol, the ED50 values of DELfp were 113 and 185.7 mg/kg, respectively. DELfp (100, 200, and 400 mg/kg) inhibited indomethacin-induced lesions by 66.7, 69.6, and 65.8%, respectively. DELfp (200 mg/kg) reduced gastric secretion and H+ concentration in the gastric contents and showed to be independent of nitric oxide (NO) and dependent on sulfhydryl (-SH) compounds in the protection of the gastric mucosa. In the chronic ulcer model, DELfp reduced the area of the gastric lesion. DELfp also showed anti-H. pylori activity. In conclusion, DELfp showed antioxidant, gastroprotective, healing, and antiulcerogenic activities. The mechanism of these actions seems to be mediated by different pathways and involves the reduction of gastric secretion and H+ concentration, dependence on sulfhydryl compounds, and anti-H. pylori activity. All these actions support the medicinal use of this species in the management of peptic ulcers.

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Nascimento da Silva, LC, J. Robson Neves Cavalcanti Filho, C. Macedo Bezerra Filho, T. Fonseca da Silva, M. Vanusa da Silva, MT dos Santos Correia, and A. Løbner-Olesen. "New insights into anti-S. aureus action of Buchenavia tetraphylla and Libidibia ferrea: inhibition of DNA replication." Planta Medica 81, S 01 (December 14, 2016): S1—S381. http://dx.doi.org/10.1055/s-0036-1596611.

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Ferreira, Magda Rhayanny Assunção, Rolf Daniels, and Luiz Alberto Lira Soares. "Development and evaluation of Classical and Pickering emulsions containing crude or fractionated extracts of Libidibia ferrea pods." Drug Development and Industrial Pharmacy 46, no. 7 (June 26, 2020): 1185–98. http://dx.doi.org/10.1080/03639045.2020.1782422.

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Borges, Laís Angélica, Luiz Gustavo Rodrigues Souza, Marcelo Guerra, Isabel Cristina Machado, Gwilym P. Lewis, and Ariadna Valentina Lopes. "Reproductive isolation between diploid and tetraploid cytotypes of Libidibia ferrea (= Caesalpinia ferrea) (Leguminosae): ecological and taxonomic implications." Plant Systematics and Evolution 298, no. 7 (May 5, 2012): 1371–81. http://dx.doi.org/10.1007/s00606-012-0643-3.

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Lima, Maria Joanellys dos Santos, Karolynne Rodrigues De Melo, Victor de Albuquerque Wanderley Sales, Myla Lôbo De Souza, Emerson de Oliveira Silva, Wyndly Daniel Cardoso Gaião, Pedro José Rolim Neto, Maria Bernadete Sousa Maia, Ivone Antônia De Souza, and Rosali Maria Ferreira Da Silva. "Libidibia ferrea extract as a promising antidiabetic agent: characterization, pre-clinical analysis and development of pharmaceutical dosage forms / Extrato de Libidibia ferrea como um promissor agente antidiabético: caracterização, análise pré-clínica e desenvolvimento de formas de dosagem farmacêutica." Brazilian Journal of Development 7, no. 4 (April 30, 2021): 43644–66. http://dx.doi.org/10.34117/bjdv7n4-699.

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Figueiredo, Talita Nunes de Castro, Jorge Luís Sousa Ferreira, Francine Neves Calil, Jácomo Divino Borges, and Carlos De Melo E Silva Neto. "Vascular epiphytes in urban trees in Goiânia city, Brazilian Cerrado." Revista Ecologia e Nutrição Florestal - ENFLO 9 (May 24, 2021): e02. http://dx.doi.org/10.5902/2316980x64867.

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The objective of this study was to evaluate the presence of epiphyte species in trees that compose the urban trees of four avenues of Goiânia city – state of Goiás. All individuals from the avenue median and sidewalks were quantified, all epiphyte host individuals were inventoried and the epiphytes found were evaluated qualitatively and quantitatively. The species Ficus rubiginosa was present in 68.63% of the cases, followed by Ficus luschnathiana (15.69%), Ficus insipida (5.88%) and Ficus guaranitica (5.88%). A total of 84.62% of the hosts are Poincianella pluviosa, 51.92% are individuals of height between 14 and 16 meters and 35.29% have a diameter between 46.00 and 61.99 cm. The hemiepiphytes occurred on Libidibia ferrea, Ceiba speciosa, Albizia lebbeck and Pachira aquatica. The occurrence of hemiepiphytes prevailed on trunk bifurcations (44.23%), branch bifurcation (19.23%), branch hollows (17.31%) and on branches and roots (3.85%). About 15.65% of each adult arboreal in Goiânia city is inferred to hold at least one epiphyte.

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Matos, Antônio César Batista, Glauciana da Mata Ataíde, and Eduardo Euclydes de Lima e. Borges. "Physiological, physical, and morpho-anatomical changes in Libidibia ferrea ((Mart. ex Tul.) L.P. Queiroz) seeds after overcoming dormancy." Journal of Seed Science 37, no. 1 (March 10, 2015): 26–32. http://dx.doi.org/10.1590/2317-1545v37n1140433.

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Seed dormancy is a phenomenon that affects the distribution of plant species in time. However, it may slow germination and consequently hinder seedling production in nurseries. Many seeds of forest species of the Fabaceae family, such as Libidibia ferrea (Brazilian ironwood), have physical dormancy caused by impermeability of the seed coat to water. Therefore, the aim of this study was to evaluate the physiological, physical, and morpho-anatomical characteristics of L. ferrea seeds before and after application of different treatments for overcoming dormancy. We evaluated the imbibition curves, germination percentage, germination speed index (GSI), the force required to puncture the micropylar region, and morpho-anatomical changes through images obtained from a scanning electron microscope (SEM) before and after application of treatments for overcoming dormancy. L. ferrea seeds immersed in sulfuric acid show a triphasic pattern of imbibition. The required force to puncture the micropylar region of L. ferrea seeds is less for both the treatment with boiling water and for treatments with sulfuric acid. In addition, the required force to puncture the micropylar region decreases during imbibition of the seeds after application of sulfuric acid. The time of application of sulfuric acid influences the thickness of the material removed from the macrosclereid layer of the seed coat.

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Falcão, Tamires Rocha, Aurigena Antunes de Araújo, Luiz Alberto Lira Soares, Iuri Brilhante de Farias, Wliana Alves Viturino da Silva, Magda Rhayanny Assunção Ferreira, Raimundo Fernandes de Araújo Jr, Juliana Silva de Medeiros, Maria Luiza Diniz de Sousa Lopes, and Gerlane Coelho Bernardo Guerra. "Libidibia ferreaFruit Crude Extract and Fractions Show Anti-Inflammatory, Antioxidant, and Antinociceptive EffectIn Vivoand Increase Cell ViabilityIn Vitro." Evidence-Based Complementary and Alternative Medicine 2019 (February 21, 2019): 1–14. http://dx.doi.org/10.1155/2019/6064805.

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Background.Libidibia ferrea(L. ferrea)is found throughout the northeastern region of Brazil, where it has been used in folk medicine with beneficial effects on many inflammatory disorders.Purpose. This study investigated the phytochemical composition of the crude extract and fractions ofL. ferreafruit and evaluated its anti-inflammatory and antinociceptive activitiesin vivoand effect on cell viabilityin vitro.Methods. Characterization of polyphenols present in crude extract (CE), hydroalcoholic fractions of 20-80% ethanol (CE20, CE40, CE60, and CE80), aqueous fraction (AqF), and ethyl acetate (EAF) fractions ofL. ferreafruit was performed by chromatographic analysis.Anti-inflammatory activity was evaluated by using a carrageenan-induced peritonitis model submitted to a leukocyte migration assay and myeloperoxidase activity (MPO) analysis. Total glutathione and malondialdehyde (MDA) levels were assessed to evaluate the oxidative stress level. Antinociceptive activity was evaluated by acetic acid-induced abdominal writhing and hot plate test.In vitrocell viability was determined by using MTT assay in a mouse embryonic fibroblast cell line (3T3 cells).Results. Chromatography revealed the presence of ellagic acid content in EAF (3.06), CE (2.96), and CE40 (2.89). Gallic acid was found in EAF (12.03), CE 20 (4.43), and CE (3.99).L. ferreacrude extract and all fractions significantly reduced leukocyte migration and MPO activity (p<0.001).L. ferreaantioxidant effect was observed through high levels of total glutathione and reduction of MDA levels (p<0.001). Acetic acid-induced nociception was significantly inhibited after administration ofL. ferreacrude extract and all fractions (p<0.001). Crude extract and all fractions significantly increased the viability of the 3T3 cell line (p<0.05).Conclusions. The appropriate extraction procedure preserves the chemical components ofL. ferreafruit, such as gallic acid and ellargic acid. Crude extract and fractions ofL. ferreafruit exhibited anti-inflammatory, antioxidant, antinociceptive activitiesin vivoand enhanced cell viabilityin vitro.

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Almeida, Ediglécia Pereira, Antonio Lucineudo de Oliveira Freire, Ivonete Alves Bakke, Cheila Deisy Ferreira, George Martins França, and Antonio Wesly Batista. "Effects of potassium in Myracrodruon urundeuva, Libidibia ferrea and Mimosa tenuiflora seedlings under a short-term water déficit." Research, Society and Development 9, no. 5 (March 29, 2020): e97953269. http://dx.doi.org/10.33448/rsd-v9i5.3269.

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This study aimed to evaluate the effects of potassium fertilization on Myracrodruon urundeuva, Libidibia ferrea and Mimosa tenuiflora seedlings submitted to a short period of water deficit. Three doses of K (0, 150 and 300 mg dm-3 KCl) and three water regimes (without water deficit, moderate water deficit and severe water deficit) were evaluated. The plants were kept in black plastic bags containing soil from the Caatinga and, 30 days after the beginning of the water regimes, the relative water content (RWC), transpiration (E), stomatal conductance (gs) and photosynthesis (A) were evaluated. High moisture content in the soil was unfavorable to plants, promoting reduction in RWC and gas exchange. The water deficit increase E, gs and A, but the intensity of these responses was variable between species. The water deficit favored L. ferrea, with elevated RWC and reduced alterations in gas exchange, demonstrating its greater tolerance in relation to the others species evaluated, however it was the species most benefited by K. The supply of 300 mg dm-3 of KCl positively influenced the water status and gas exchange of the studied species with an increase in the water deficit. We suggest the development of research subjecting the plants to a longer period of time, in order to establish a better relationship between potassium and the increased tolerance of these plants to water deficit.

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Pickler, Thaisa B., Karina P. Lopes, Stefani A. Magalhães, Clarissa M. A. Krueger, Milene M. Martins, Valdir Cechinel Filho, Angela F. Jozala, Denise Grotto, and Marli Gerenutti. "Effect of Libidibia ferrea bark and seed in maternal reproductive and biochemical outcomes and fetal anomaly in rats." Birth Defects Research 111, no. 13 (May 21, 2019): 863–71. http://dx.doi.org/10.1002/bdr2.1520.

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Journal articles on the topic 'Libidibia'

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