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Journal articles on the topic 'Lichenoid eruption'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Mohammed, Fayeza, Laura L. Wally, Jeffrey E. Karaban, Vijaya B. Reddy, and Yongsuk Lertratanakul. "Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit." Case Reports in Dermatology 9, no. 3 (2017): 236–42. http://dx.doi.org/10.1159/000484471.

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A lichenoid drug eruption is a rare side effect which can occur following the administration of several different medications. Here we describe a unique case of fenofibrate as the causative agent of a lichenoid drug eruption. This case highlights a rare and clinically significant dermatologic side effect of fenofibrate. In addition, we report a potential familial association which underscores the potential for underlying genetic mechanisms to be contributory to lichenoid drug eruptions. A reminder of the physical characteristics of lichen planus, knowledge of the temporal relation between admi

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2

Kunadia, Anuj, Kenneth Shulman, and Naveed Sami. "Certolizumab-induced lichenoid eruption in a patient with rheumatoid arthritis." BMJ Case Reports 14, no. 12 (2021): e245875. http://dx.doi.org/10.1136/bcr-2021-245875.

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Certolizumab is a monoclonal antibody against tumour necrosis factor-alpha (TNF-α) commonly used in rheumatologic conditions such as rheumatoid arthritis. Skin rashes are an uncommon side effect with few cases of lichenoid drug eruption reported in the literature. We describe a patient with rheumatoid arthritis who presented 6 weeks after initiating certolizumab pegol. Physical examination showed pink-to-violaceous papules on her upper and lower extremities. Biopsy confirmed a lichenoid drug eruption. The medication was discontinued and she was treated with topical steroids and a calcineurin i

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3

Singh, Shivani, Noorin Zaidi, Sumaiya Irfan, and Nirupma Lal. "Lichen scrofulosorum- A rare case report." Indian Journal of Pathology and Oncology 10, no. 3 (2023): 297–99. http://dx.doi.org/10.18231/j.ijpo.2023.065.

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Lichen scrofulosorum, other name “tuberculosis cutis lichenoides” which is present as lichenoid eruption of minute papules, a rare tuberculid commonly seen in children and adolescents with tuberculosis. Mostly positive tuberculin reaction strongly associated with eruption. Diagnosis can be difficult in this type of lesion which is closely resemble to other type of dermatological conditions that are often primarily considered. Here we report a case of lichen scrofulosorum in a twenty year- old female having typical grouped lichenoid papules on the neck, hand and leg associated with itching.

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4

Amine, Ennaciri Mohamed, Basri Ghita, Zemmez Youssef, et al. "Metformin Induced Lichenoïd Drug Eruption." Scholars Journal of Medical Case Reports 12, no. 12 (2024): 2048–51. https://doi.org/10.36347/sjmcr.2024.v12i12.011.

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Cutaneous lichenoid drug eruptions are rare adverse drug reactions reminiscent of lichen planus. The most frequently reported culprit drugs are Checkpoint inhibitors, tyrosine kinase inhibitors and TNF-α inhibitors, but other drugs can also be responsible. This case-report is about a 49-year-old woman with a history of type 2 diabetes. She started taking metformin 160 weeks before the onset of a pruritic lichenoid rash on the trunk and limbs, of which the histopathology was in favor of an adverse cutaneous lichenoid drug eruption caracterized by the presence of eosinophilic polynuclei in the p

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5

T. S., Rajashekar, Shruthi Madhavi G., and Suresh Kumar Kuppuswamy. "Imatinib mesylate induced lichenoid drug eruption masquerading as small plaque parapsoriasis." International Journal of Research in Dermatology 4, no. 2 (2018): 262. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20181832.

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<p class="abstract">Imatinib mesylate (IM) is a tyrosine kinase inhibitor approved for chronic myeloid leukemia, gastrointestinal stromal tumor and few dermatological conditions such as dermatofibrosarcoma protruberans, systemic sclerosis and systemic mastocytosis among other conditions. It is known to cause non lichenoid eruptions commonly and rarely it can cause lichenoid drug eruption. Small plaque parapsoriasis is a monoclonal T cell disorder with clinical similarity to psoriasis characterised by small sized plaques with digitate appearance.We report a case of 75 year old male on IM

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6

Manko, Svitlana, Benoît Côté, and Nathalie Provost. "A case of durvalumab-induced lichenoid eruption evolving to bullous eruption after phototherapy: A case report." SAGE Open Medical Case Reports 9 (January 2021): 2050313X2199327. http://dx.doi.org/10.1177/2050313x21993279.

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Immune checkpoint inhibitor therapy nowadays became a treatment for a wide range of cancers, and may be responsible for various dermatologic adverse effects, including bullous eruptions. In our report, we present a case of late-onset immunotherapy-induced eruption in a 62-year-old woman treated with anti-programmed cell death-L1 agent durvalumab for metastatic squamous cell carcinoma. Diagnosed as lichenoid dermatitis upon initial presentation, this eruption evolved into necrotic bullous dermatitis after several weeks of phototherapy, with histology and direct immunofluorescence study favoring

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7

Adams, Amy E., Arthur M. Bobrove, and Anita C. Gilliam. "Statins and “Chameleon-Like” Cutaneous Eruptions: Simvastatin-Induced Acral Cutaneous Vesiculobullous and Pustular Eruption in a 70-Year-Old Man." Journal of Cutaneous Medicine and Surgery 14, no. 5 (2010): 207–11. http://dx.doi.org/10.2310/7750.2010.09042.

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Background: The statin medications for lowering of blood cholesterol can be associated with cutaneous lichenoid reactions but also a variety of other adverse cutaneous eruptions, including Stevens-Johnson syndrome, toxic epidermolytic necrolysis, porphyria cutanea tarda, linear IgA bullous dermatosis, and reaction patterns (lupus and dermatomyositis-like and pustular). Cutaneous eruptions (“eczema” in the product literature) owing to simvastatin are reported in approximately 1.5% individuals compared with placebo. Objective: To correlate the clinical and microscopic features of an unusual vesi

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8

SHIRAISHI, SATOSHI. "Lichenoid drug eruption." Nishi Nihon Hifuka 48, no. 3 (1986): 443–46. http://dx.doi.org/10.2336/nishinihonhifu.48.443.

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9

SHIMIZU, Chihiro, Hiroyoshi HANAKAWA, and Norio OHTSUKI. "Lichenoid Drug Eruption." Nishi Nihon Hifuka 60, no. 4 (1998): 494–97. http://dx.doi.org/10.2336/nishinihonhifu.60.494.

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10

Büyükgebiz, Benal, Nur Arslan, Yeşim Oztürk, Cüneyt Soyal, and Banu Lebe. "Drug Reaction To Ursodeoxycholic Acid: Lichenoid Drug Eruption In An Infant Using Ursodeoxycholic Acid For Neonatal Hepatitis." Journal of Pediatric Gastroenterology and Nutrition 35, no. 3 (2002): 384–86. http://dx.doi.org/10.1002/j.1536-4801.2002.tb07842.x.

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ABSTRACTLichenoid drug eruptions are skin reactions associated with a number of drugs and chemicals. They are rare in infants. We report here an infant who presented with neonatal hepatitis and who was being treated with ursodeoxycholic acid. The infant developed lichenoid skin eruptions in the third week of the therapy. The lesions have resolved two months after the discontinuation of the drug. To our knowledge, this is the first infant case of lichenoid drug eruption associated with ursodeoxycholic acid.

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11

ATKIN, S. L., T. M. M. MCKENZIE, and C. J. STEVENSON. "Carbamazepine-induced lichenoid eruption." Clinical and Experimental Dermatology 15, no. 5 (1990): 382–83. http://dx.doi.org/10.1111/j.1365-2230.1990.tb02122.x.

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12

PHILLIPS, W. G., S. VAUGHAN-JONES, R. JENKINS, and S. M. BREATHNACH. "Captopril-induced lichenoid eruption." Clinical and Experimental Dermatology 19, no. 4 (1994): 317–20. http://dx.doi.org/10.1111/j.1365-2230.1994.tb01203.x.

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13

Armour, Katherine, and Patricia Lowe. "Complicated lichenoid drug eruption." Australasian Journal of Dermatology 46, no. 1 (2005): 21–24. http://dx.doi.org/10.1111/j.1440-0960.2005.00131.x.

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14

Guijarro, J., R. Botella, J. Bañuls, J. Navas, L. Carnero, and R. Alfonso. "PLASMA CELL LICHENOID ERUPTION." American Journal of Dermatopathology 20, no. 6 (1998): 589. http://dx.doi.org/10.1097/00000372-199812000-00021.

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15

Ivory, Joannie, Matthew Sochat, John Galatowitsch, and Sofia Ghani. "Anastrozole-Associated Lichenoid Eruption." American Journal of Therapeutics 27, no. 6 (2020): e658-e660. http://dx.doi.org/10.1097/mjt.0000000000001029.

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16

Piérard, Eric, Emmanuel Delaporte, René-Marc Flipo, et al. "Tiopronin-induced lichenoid eruption." Journal of the American Academy of Dermatology 31, no. 4 (1994): 665–67. http://dx.doi.org/10.1016/s0190-9622(08)81735-5.

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17

Aouam, Karim, Hichem BelHadj Ali, Amel Chaabane, Montassar Amri, Naceur Boughattas, and Jameleddine Zili. "Hydrochlothiazide-induced lichenoid eruption." World Allergy Organization Journal &NA; (November 2007): S279. http://dx.doi.org/10.1097/01.wox.0000301441.99569.0f.

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18

How, Ooi Jun, Rosediani Muhamad, Rubinderan Muthusamy, Fairuz Abdul Rahman, and Maryam Mohd Zulkifli. "Amlodipine-induced lichenoid drug eruption: A case report." Bangladesh Journal of Medical Science 22, no. 1 (2023): 229–33. http://dx.doi.org/10.3329/bjms.v22i1.61853.

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Lichenoid drug eruption is a rare side effect which may occur following administration of several types of medication. The pathogenesis of lichenoid drug eruption is postulated to be due to persistent activation of CD8 T lymphocytes against epidermal cells. There were only a few cases of Amlodipine-induced lichenoid drug eruption reported in literature. Due to the rare occurrence, this disease might be overlooked and lead to delayed diagnosis and treatment. It is vital for the attending medical practitioner to be able to diagnose this disease as amlodipine was found to be the most utilised med

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19

Smith, Kathleen J., Andrew L. Dutka, and Henry G. Skelton. "Lichenoid/Interface Cutaneous Eruptions to IVIg with the Primary Infusion May Be Related to the Re-Regulation of Anti-Idiotype Network." Journal of Cutaneous Medicine and Surgery 3, no. 2 (1998): 96–101. http://dx.doi.org/10.1177/120347549800300209.

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Background: Intravenous immunoglobulin (IVIg) has been used in recent years to treat an increasing number of autoimmune diseases to decrease cytokine secretion and to neutralize toxins, in addition to the therapy of immunodeficiency disorders. In addition to angioedema-like hypersensitivity eruptions, there have been reports of eczematous, purpuric, petechial/purpuric, and vasculitic reactions to IVIg; however, there has been only one previous report of a case in which the patient developed a lichenoid dermatitis after infusion of IVIg. Observations: We present two patients with chronic inflam

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20

Ambur, Austin, Aashni Bhukhan, Charles Dunn, and Rajiv Nathoo. "Photodistributed Lichenoid Eruption with Alopecia: A Unique Presentation of Graham–Little–Piccardi–Lasseur Syndrome." International Journal of Trichology 15, no. 4 (2023): 154–56. http://dx.doi.org/10.4103/ijt.ijt_47_22.

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Graham–Little–Piccardi–Lasseur syndrome (GLPLS) is characterized by diffuse alopecia and a lichenoid follicular eruption affecting the scalp, eyebrows, and intertriginous regions. It is considered a variant of lichen planopilaris. The condition often begins as hyperkeratotic papules on the trunk and extremities followed by the development of alopecia. Several subtypes of lichen planus have been associated with a photodistriubuted eruption including lichenoid drug reactions, actinic lichen planus, and lichen planus pigmentosus; however, there are no reported cases associated with GLPLS. We here

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21

Fouzia, Hali, Abbour Anass, Marnissi Farida, Razzouki Ibtissam, and Chiheb Soumiya. "COVID-19 Vaccine-Induced Lichenoid Drug Eruption." International Journal of Medical Science and Clinical Research Studies 05, no. 02 (2025): 272–74. https://doi.org/10.5281/zenodo.14843991.

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The global rollout of COVID-19 vaccines has been a significant step in controlling the SARS-CoV-2 pandemic. While the vaccines have proven to be generally safe, adverse reactions, including both local and systemic effects, have been observed. Cutaneous manifestations, though rare, have been reported in some instances.  We report the case of a 67-year-old male who developed pruritic erythematous-to-violaceous papules and plaques three days after receiving the second dose of a COVID-19 vaccine. The lesions were found on the right inner thigh, forearms, trunk, and neck. Histopathological exa

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22

Sharma, Prafulla Kumar, Ram Krishna Gautam, Meenakshi Bhardwaj, and Hemant Kumar Kar. "Isonicotinic Acid Hydrazide Induced Anagen Effluvium and Associated Lichenoid Eruption." Journal of Dermatology 28, no. 12 (2001): 737–41. http://dx.doi.org/10.1111/j.1346-8138.2001.tb00069.x.

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AbstractA 32 year‐old woman developed generalised lichenoid eruptions on her body followed by diffuse loss of scalp hair of the anagen effluvium type. She was receiving several anti‐tubercular drugs, including rifampicin, isonicotinic acid hydrazide (INH), pyrazinamide, and ethambutol, for abdominal tuberculosis. INH, which is a leading cause of drug eruptions in the above group of drugs was withdrawn. However, the other antitubercular drugs were continued along with 40 mg of prednisolone in a single daily morning dose. The latter was discontinued slowly over a period of 10 weeks. There was co

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23

Esfahani, Khashayar, Meagan-Helen Henderson Berg, Hanieh Zargham, et al. "Narrowband ultraviolet B therapy for refractory immune-related lichenoid dermatitis on PD-1 therapy: a case report." Journal for ImmunoTherapy of Cancer 9, no. 3 (2021): e001831. http://dx.doi.org/10.1136/jitc-2020-001831.

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Treatment with programmed cell death 1 inhibitors is associated with a wide range of cutaneous immune-related adverse events, with lichenoid eruptions representing one of the major cutaneous toxicities. We describe the case of an 81-year-old man with metastatic melanoma treated with pembrolizumab who subsequently developed a delayed-onset generalized lichenoid dermatitis. After failing multiple lines of systemic immunosuppression, narrowband ultraviolet B (NBUVB) phototherapy three times per week for 17 sessions resulted in a significant clinical response in his cutaneous eruption and was well

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24

Gupta, Mrinal, Heena Gupta, and Anish Gupta. "Tenofovir induced lichenoid drug eruption." Avicenna Journal of Medicine 5, no. 3 (2015): 95. http://dx.doi.org/10.4103/2231-0770.160250.

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25

Prabhash, K., and DC Doval. "Lichenoid eruption due to imatinib." Indian Journal of Dermatology, Venereology and Leprology 71, no. 4 (2005): 287. http://dx.doi.org/10.4103/0378-6323.16627.

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26

MIYACHI, Motoko, Ritsuko KUNITAKE, Nobuo HIROTA, Shinichi IMAFUKU, and Juichiro NAKAYAMA. "Cycloserine-induced Lichenoid Drug Eruption." Nishi Nihon Hifuka 73, no. 1 (2011): 44–48. http://dx.doi.org/10.2336/nishinihonhifu.73.44.

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27

Shim, J. H., T. Y. Kim, H. O. Kim, and C. W. Kim. "Cycloserine-lnduced Lichenoid Drug Eruption." Dermatology 191, no. 2 (1995): 142–44. http://dx.doi.org/10.1159/000246533.

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28

ROGER, D., F. ROLLE, F. LABROUSSE, A. BROSSET, and J. M. BONNETBLANC. "Simvastatin-induced lichenoid drug eruption." Clinical and Experimental Dermatology 19, no. 1 (1994): 88–89. http://dx.doi.org/10.1111/j.1365-2230.1994.tb01128.x.

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29

Zheng, Yue, Jie Zhang, Haiyan Chen, Wei Lai, and Howard I. Maibach. "Terbinafine-induced lichenoid drug eruption." Cutaneous and Ocular Toxicology 36, no. 1 (2016): 101–3. http://dx.doi.org/10.3109/15569527.2016.1160101.

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30

Powell, Mindy L., Alison Ehrlich, and Donald V. Belsito. "Lichenoid drug eruption to salsalate." Journal of the American Academy of Dermatology 45, no. 4 (2001): 616–19. http://dx.doi.org/10.1067/mjd.2001.114593.

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31

Kawabe, Yoko, Nobuyuki Mizuno, Kunihiko Yoshikawa, and Yoshifuji Matsumoto. "Lichenoid Eruption due to Mercaptopropionylglycine." Journal of Dermatology 15, no. 5 (1988): 434–39. http://dx.doi.org/10.1111/j.1346-8138.1988.tb04082.x.

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32

Sergeant, A., G. Milne, and F. Shaffrali. "Lichenoid eruption associated with orlistat." British Journal of Dermatology 154, no. 5 (2006): 1020–21. http://dx.doi.org/10.1111/j.1365-2133.2006.07220.x.

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33

El Habr, Constantin, Zarouwi Meguerian, and Rita Sammour. "Adalimumab - Induced Lichenoid Drug Eruption." Lebanese Medical Journal 62, no. 4 (2014): 238–40. http://dx.doi.org/10.12816/0008295.

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34

O'Brien, Timothy J., Ian G. Lyall, and Suzanne S. Reid. "LICHENOID ERUPTION INDUCED BY SOTALOL." Australasian Journal of Dermatology 35, no. 2 (1994): 93–94. http://dx.doi.org/10.1111/j.1440-0960.1994.tb00907.x.

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35

Pua, Vernon SC, Richard A. Scolyer, and Ross StC Barnetson. "Pravastatin-induced lichenoid drug eruption." Australasian Journal of Dermatology 47, no. 1 (2006): 57–59. http://dx.doi.org/10.1111/j.1440-0960.2006.00225.x.

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36

Koh, M. J. A., P. P. Seah, Y. K. Tay, and K. Mancer. "Lichenoid drug eruption to terazosin." British Journal of Dermatology 158, no. 2 (2007): 426–27. http://dx.doi.org/10.1111/j.1365-2133.2007.08331.x.

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37

Grossman, Marc E., Kelly Warren, Attila Mady, and Karin H. Satra. "Lichenoid eruption associated with ethambutol." Journal of the American Academy of Dermatology 33, no. 4 (1995): 675–76. http://dx.doi.org/10.1016/0190-9622(95)91307-6.

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38

Lim, Davin, and James Muir. "Lichenoid eruption to STI 571." American Journal of Hematology 70, no. 2 (2002): 179. http://dx.doi.org/10.1002/ajh.10105.

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39

Sapadin, Yonatan K., Elazar Mermelstein, Robert G. Phelps, Christopher F. Basler, JoAnn M. Tufariello, and Mark G. Lebwohl. "COVID-19 Vaccine-Induced Lichenoid Eruptions—Clinical and Histopathologic Spectrum in a Case Series of Fifteen Patients with Review of the Literature." Vaccines 11, no. 2 (2023): 438. http://dx.doi.org/10.3390/vaccines11020438.

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Lichen planus is a distinctive mucocutaneous disease with well-established clinical and histopathologic criteria. Lichenoid eruptions closely resemble lichen planus and may sometimes be indistinguishable from it. Systemic agents previously associated have included medications, viral infections and vaccines. Sporadic case reports of lichen planus and lichenoid reactions associated with COVID-19 vaccines have recently emerged. Herein, we review the world literature (31 patients) and expand it with a case series of 15 patients who presented with vaccine-induced lichenoid eruption (V-ILE). The spe

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40

Alkhuzaim, OsamahM. "Lichenoid drug eruption induced by chlordiazepoxide." Journal of Dermatology and Dermatologic Surgery 26, no. 3 (2022): 29. http://dx.doi.org/10.4103/jdds.jdds_35_20.

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41

Molina-López, Irene, Ana-Candida Villanueva, Verónica Parra-Blanco, Ricardo Suárez-Fernández, and Minia Campos-Domínguez. "DeRmpath & Clinic: Linear lichenoid eruption." European Journal of Dermatology 26, no. 3 (2016): 327–28. http://dx.doi.org/10.1684/ejd.2016.2814.

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42

Sharma, Geeta, Kajal Aggarwal, and Jasleen Kaur Sandhu. "Lichenoid pseudovesicular papular eruption on nose." Cosmoderma 2 (September 30, 2022): 88. http://dx.doi.org/10.25259/csdm_83_2022.

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43

C LARK and D OUGLAS. "Lichenoid drug eruption induced by spironolactone." Clinical and Experimental Dermatology 23, no. 1 (1998): 43–44. http://dx.doi.org/10.1046/j.1365-2230.1998.00281.x.

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44

Akin Belli, Asli, Gonen Mengi, Yelda Dere, and Gursoy Dogan. "Lichenoid drug eruption induced by colchicine." Dermatologic Therapy 29, no. 1 (2015): 7–9. http://dx.doi.org/10.1111/dth.12301.

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45

Cruz, Maria João, Ana Filipa Duarte, Teresa Baudrier, Ana Paula Cunha, Filomena Barreto, and Filomena Azevedo. "Lichenoid drug eruption induced by misoprostol." Contact Dermatitis 61, no. 4 (2009): 240–42. http://dx.doi.org/10.1111/j.1600-0536.2009.01616.x.

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46

Ladhari, C., N. Fathallah, S. Mokni, B. Sriha, and C. Ben Salem. "Lichenoid drug eruption associated with rifampicin." La Presse Médicale 47, no. 3 (2018): 281–82. http://dx.doi.org/10.1016/j.lpm.2018.01.007.

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47

Kanwar, A. J., S. Dhar, and S. Ghosh. "Photosensitive Lichenoid Eruption due to Enalapril." Dermatology 187, no. 1 (1993): 80. http://dx.doi.org/10.1159/000247209.

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48

Fernández-Torres, R., M. Almagro, J. del Pozo, et al. "Lichenoid Drug Eruption Induced by Olanzapine." Actas Dermo-Sifiliográficas (English Edition) 99, no. 3 (2008): 221–24. http://dx.doi.org/10.1016/s1578-2190(08)70236-1.

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49

Matsuzaki, Yasushi, Tadashi Yoshida, and Hajime Takikawa. "Does ursodeoxycholic acid cause lichenoid eruption?" Gastroenterology 122, no. 5 (2002): 1547. http://dx.doi.org/10.1016/s0016-5085(02)80269-4.

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50

Walker, Greg, Natalie Lane, and Palak Parekh. "Photosensitive lichenoid drug eruption to capecitabine." Journal of the American Academy of Dermatology 71, no. 2 (2014): e52-e53. http://dx.doi.org/10.1016/j.jaad.2014.01.884.

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