Journal articles: 'Lidocaína endovenosa'

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Starobin, Daniel, Gennady Smirnov, Daniel Bendayan, et al. "A eficácia da lidocaína local versus a lidocaína endovenosa na supressão da tosse durante a broncofibroscopia." Revista Portuguesa de Pneumologia 8, no. 5 (2002): 483–84. http://dx.doi.org/10.1016/s0873-2159(15)30782-0.

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González, María Magdalena, and Fernando Altermatt. "Is intravenous lidocaine effective for decreasing pain and speeding up recovery after surgery?" Medwave 17, no. 09 (2017): e7121-e7121. http://dx.doi.org/10.5867/medwave.2017.09.7121.

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Viarengo, Luiz Marcelo Aiello, Guilherme Vieira Meirelles, and João Potério Filho. "Tratamento de varizes com laser endovenoso: estudo prospectivo com seguimento de 39 meses." Jornal Vascular Brasileiro 5, no. 3 (2006): 184–93. http://dx.doi.org/10.1590/s1677-54492006000300006.

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OBJETIVO: Avaliar os resultados da terapêutica endovenosa com laser no tratamento de varizes primárias. PACIENTES E MÉTODO: No período compreendido entre julho de 2001 e setembro de 2004 (39 meses), 253 pacientes (417 membros) foram tratados ambulatorialmente com laser de diodo de 810 e 980-nm, com energia liberada endovenosamente através de fibra óptica introduzida por punção guiada por eco-Doppler. Foi utilizada anestesia por infiltração intumescente perivasal com solução de lidocaína a 0,2% (50-150 ml). A potência e duração do pulso foram determinadas pelo diâmetro da veia. Os controles foram realizados com eco-Doppler aos 7 dias, 1 mês, 3 meses, 6 meses, 1 ano e, a seguir, anualmente, para avaliar a eficácia do tratamento e os efeitos adversos. RESULTADOS: A oclusão primária da veia safena magna foi obtida em 405 dos 417 membros (97,1%) tratados. Houve reintervenção em 12 casos (2,9%), com sucesso. O tempo médio de observação foi de 18 meses, e, nesse período, a taxa de recidiva global de varizes foi de 7,4%, sendo 6,3% (26 membros) veias colaterais tributárias da crossa e 1,2% (cinco membros) com recanalização da safena magna. Todas as recorrências ocorreram entre o terceiro e o 12º mês. Os efeitos indesejáveis mais freqüentes foram: equimoses (60,6%); dor suportável durante o procedimento (16,1%); hematomas (5,5%); flebite em colaterais não-tratadas (3,4%); hiperpigmentação (2,9%); e parestesia transitória (3,4%). Nenhum caso de tromboflebite da safena magna foi observado. Não houve nenhum caso de trombose venosa profunda ou embolia pulmonar. CONCLUSÃO: O tratamento endovenoso de varizes com laser, conforme descrito, foi eficaz para ocluir a safena magna e seus principais ramos, com efeitos adversos autolimitados e com recorrência inferior a 8% no período de seguimento.

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Couceiro, Tania Cursino de Menezes, and Marcelo Moraes Valença. "Lidocaína endovenosa no tratamento da síndrome SUNCT secundária a tumor de hipófise: seguimento de uma paciente por um período de quatro anos. Relato de caso." Revista Dor 14, no. 4 (2013): 320–22. http://dx.doi.org/10.1590/s1806-00132013000400017.

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Vivancos, Gustavo Gameiro, Jyrson Guilherme Klamt, and Luís Vicente Garcia. "Efeito da utilização de 2 mg.kg-1 de lidocaína endovenosa na latência de duas doses diferentes de rocurônio e na resposta hemodinâmica à intubação traqueal." Revista Brasileira de Anestesiologia 61, no. 1 (2011): 6–12. http://dx.doi.org/10.1590/s0034-70942011000100001.

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Mascaro Sánchez, Pedro. "Atención integral postaborto, en el Instituto Especializado Materno Perinatal. 1995 - 2004." Revista Peruana de Ginecología y Obstetricia 53, no. 3 (2015): 187–92. http://dx.doi.org/10.31403/rpgo.v53i1033.

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OBJETIVOS. Evaluar la experiencia en la aplicación del modelo: manejo ambulatorio y atención integral del aborto. DISEÑO. Estudio clínico retrospectivo. LUGAR. Instituto Especializado Materno Perinatal (IEMP), hospital de enseñanza. PARTICIPANTES. Mujeres con aborto de menos de 12 semanas. INTERVENCIONES. Se analizó los casos de aborto atendidos en la institución, en la década 1995 a 2004. Se comparó los procedimientos efectuados, como legrado uterino instrumental y aspiración manual endouterina (AMEU), así como los diagnósticos que justificaron la intervención quirúrgica. Se evaluó las complicaciones presentadas con AMEU y legrado uterino, la consejería efectuada y los métodos de planificación familiar postaborto, aplicados como parte de la atención integral. PRINCIPALES MEDIDAS DE RESULTADOS. Tipo de atención quirúrgica y complicaciones del aborto, consejería postaborto y costos. RESULTADOS. Entre los años 1995 y 2004, se atendió en el IEMP 58 757 casos de abortos, de los cuales 19 295 (32,8%) fueron resueltos ambulatoriamente (47,3% en el 2004). El método más usado fue la AMEU (92,1%), habiéndose comunicado pocas complicaciones (1,87%), siendo estas por AMEU insuficiente, hematometra, endometritis postaborto y enfermedad inflamatoria pélvica. La analgesia utilizada fue el bloqueo paracervical con lidocaína o petidina endovenosa. Las pacientes permanecieron en emergencia un promedio de 2 a 4 horas, siendo el costo del manejo del aborto ambulatorio ampliamente ventajoso con relación a un aborto con hospitalización. En 81,1% de los casos se hizo consejería y 50,4% salió con un método anticonceptivo. CONCLUSIONES. La clásica atención del aborto con hospitalización en el IEMP ha pasado a ser atención ambulatoria integral en el Servicio de Emergencia. Este modelo, propuesto por el Ministerio de Salud y Pathfinder, para la atención integral postaborto, ha sido validado e institucionalizado por etapas; el proyecto concluyó en el año 2002 y su aplicación es vigente, con amplias ventajas para la paciente y la institución.

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Wright, Thomas F., Giulietta F. Brunetti, and Patrick Kennedy. "Lidocaine safety after saphenous vein tumescent anesthesia." Phlebology: The Journal of Venous Disease 34, no. 10 (2019): 683–89. http://dx.doi.org/10.1177/0268355519836834.

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Objectives For endovenous thermal ablation of the saphenous veins, tumescent lidocaine anesthesia is often used. Unfortunately, information is sparse on the pharmacokinetics of lidocaine absorption and its maximum safe dose. The aim of this study was to evaluate plasma concentration of lidocaine on 12 lead electrocardiograms (ECGs) and symptoms over time after the administration of tumescent lidocaine during endovenous thermal ablation procedures in healthy volunteers. Methods An observational study of symptoms, 12 lead ECGs, and serum lidocaine levels were obtained following the administration of either 15 mg/kg lidocaine or 35 mg/kg lidocaine in the perivenous saphenous space under ultrasound guidance. Blood was drawn at regular intervals in heparinized tubes and spun at 3000 r/min for 10 min. The plasma lidocaine levels were plotted vs. time for statistical comparisons. Results With the 35 mg/kg dose, four of 11 participants developed symptoms of lidocaine toxicity at 40 min, which resolved by 180 min. The 35 mg/kg dose resulted in a mean serum lidocaine peak of 2.55 µg/ml at 60 min. The 15 mg/kg dose did not result in any symptoms of lidocaine toxicity, and it resulted in a serum lidocaine plateau of 0.85 µg/ml at 180 min. No significant changes were seen on the 12-lead ECG after the administration of lidocaine at either dose. Conclusions The 15 mg/kg total lidocaine dose did not cause symptoms and appears to be a safe lidocaine dosage for tumescent anesthesia for saphenous endovenous thermal ablations. The 35 mg/kg lidocaine dose is associated with lidocaine toxicity. More study on the maximal safe dose of lidocaine for endovenous thermal ablations is needed.

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Komarova, L. N. "Experience of using solutions for tumescent anesthesia with endovenous radiofrequency obliteration: a comparative study." Medical Science And Education Of Ural 21, no. 3 (2020): 59–64. http://dx.doi.org/10.36361/1814-8999-2020-21-3-59-64.

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The incidence of varicose disease of the lower extremities throughout the world remains at a fairly high level. Given its socio-economic significance, low-impact surgical treatment methods continue to improve, as well as methods of anesthesia for them. In most cases, the mixtures used for infiltration anesthesia during endovenous surgery include lidocaine and adrenaline. The active substance of adrenaline, epinephrine hydrochloride, has a direct stimulating effect on α- and β-adrenergic receptors, and can cause serious disturbances in the cardiovascular system. It is not recommended for patients with CVD and endocrine system pathologies. Aim. minimize pain when performing tumescent anesthesia during endovenous radiofrequency obliteration of veins. Material and Methods. A comparative study was performed in which 192 patients with clinical forms of chronic C2-C6 venous disease took part. All patients using the envelope method were divided into three groups: patients of the first group (I) planned to perform RFO and miniphlebectomy using Klein mixture for tumescent anesthesia, the pH of which was 6.6, lidocaine concentration 0.04%. Patients of the second group (II) planned anesthesia using a solution, the pH of which was 7.3, the concentration of lidocaine was 0.02%. In patients of the third group (III), a solution with a pH of 7.4 was used, the concentration of lidocaine was 0.08%. The level of pain during the administration of the anesthetic was evaluated using two scales – the verbal descriptive scale of pain assessment (VASOB) and the visual analogue scale (VAS). Results. Patient groups were comparable in age, sex, clinical form of the disease. When assessing pain on a verbal descriptive scale, 50% of patients (27) in group II noted a complete absence of pain during tumescent anesthesia, in group III – 54.5% (48). Very severe pain (8 points) was noted by 4 patients from Group I, who were anesthetized by administering a Klein mixture, which constituted 8%; unbearable pain (10 points) also noted two patients from this group (4%). According to YOUR, the average pain in the first group was 3.02 ± 1.07, in the second – 1.13 ± 0.23, in the third – 0.93 ± 0.27 (p = 0.05). Pronounced pain (more than 5 cm according to YOUR) was noted only in the first group in 12 patients (24%). Conclusion. None of the test solutions completely removed pain during tumescent paravasal anesthesia. But the use of a solution with a pH of 7.3-7.4 is less painful when administered and significantly reduces pain during tumescent anesthesia, which was used in patients of groups II and III.

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Hudson, Arlene J., David R. Whittaker, Dale F. Szpisjak, Mark J. Lenart, and Mercedes M. Bailey. "Tumescent technique without epinephrine for endovenous laser therapy and serum lidocaine concentration." Journal of Vascular Surgery: Venous and Lymphatic Disorders 3, no. 1 (2015): 48–53. http://dx.doi.org/10.1016/j.jvsv.2014.07.006.

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Wallace, Tom, Clement Leung, Sandip Nandhra, Nehemiah Samuel, Daniel Carradice, and Ian Chetter. "Defining the optimum tumescent anaesthesia solution in endovenous laser ablation." Phlebology: The Journal of Venous Disease 32, no. 5 (2016): 322–33. http://dx.doi.org/10.1177/0268355516653905.

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Objectives To produce a tumescent anaesthesia solution with physiological pH for endovenous thermal ablation and evaluate its influence on peri- and postoperative pain, clinical and quality of life outcomes, and technical success. Methods Tumescent anaesthetic solution (0.1% lidocaine with 1:2,000,000 epinephrine) was titrated to physiological pH by buffering with 2 ml incremental aliquots of 8.4% sodium bicarbonate. Patients undergoing great saphenous vein endovenous laser ablation and ambulatory phlebectomy were studied before and after introduction of buffered tumescent anaesthetic. Primary outcome was perioperative pain measured on a 10 cm visual analogue scale. Secondary outcomes were daily pain scores during the first postoperative week, complications, time to return to normal activity, patient satisfaction, generic and disease-specific quality of life, and technical success. Patients were assessed at baseline, and at 1, 6 and 12 weeks following the procedure. Results A physiological pH was achieved with the addition of 10 ml of 8.4% sodium bicarbonate to 1 l of standard tumescent anaesthetic solution. Sixty-two patients undergoing great saphenous vein endovenous laser ablation with phlebectomy were recruited before and after the introduction of buffered tumescent anaesthetic solution. Baseline and operative characteristics were well matched. The buffered solution was associated with significantly lower (median (interquartile range)) periprocedural pain scores (1 (0.25–2.25) versus 4 (3–6), p < 0.001) and postoperative pain score at the end of the treatment day (1.8 (0.3–2.8) versus 3.0 (1.2–5.2), p = 0.033). There were no significant differences in postoperative pain scores between the groups at any other time. There were no significant differences in other clinical outcomes between the groups. Both groups demonstrated significant improvements in generic and disease-specific quality of life, with no intergroup differences. Both groups demonstrated 100% ultrasonographic technical success at all time points. Conclusions Buffering of tumescent anaesthetic solution during endovenous thermal ablation is a simple, safe, inexpensive and effective means of reducing perioperative and early postoperative pain.

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Mamede, Rui Celso Martins, and Helder Raful. "Comparação da anestesia geral e bloqueio do plexo cervical superficial em tireoidectomias parciais." Revista Brasileira de Otorrinolaringologia 74, no. 1 (2008): 99–105. http://dx.doi.org/10.1590/s0034-72992008000100016.

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Tireoidectomia sob efeito de bloqueio do plexo cervical superficial (BPCS) tem sofrido resistência. OBJETIVO: Comparar variáveis cirúrgicas e anestésicas, custos do tratamento e grau de satisfação de pacientes submetidos à hemitireoidectomia sob efeito de anestesia geral e BPCS. CASUÍSTICA E MÉTODOS: Foram 21 pacientes submetidos à anestesia geral (AG) e outro tanto ao BPCS. Após sedação, no grupo com BPCS, usou-se marcaína com vasoconstritor, e quando necessário, lidocaína a 2% com vasoconstritor. Sedação intra-operatória com diazepam endovenoso e metoprolol para controle da PA e FC eram administradas quando necessário. Usou-se anestesia geral (AG) segundo padronização do serviço. RESULTADOS: Foram significantes (p<0,05, teste t de Student) para o tempo de cirurgia (ag111,4:bpcs125,5 min), tempo de anestesia (ag154,1:bpcs488,6 min), tempo de permanência na sala cirúrgica (ag15:bpcs1 min), custos do tratamento (ag203,2:bpcs87,4 R$), presença de bradicardia (ag0:bpcs23,8%) e lesão laringotraqueal (ag51:bpcs0%). Como resultados não significativos tiveram: tempo de internação (ag17,3:bpcs15,1 hora); volume de sangramento (ag41,9:bpcs47,6 gr), tamanho da peça operatória (ag52,1:bpcs93,69 cm3) e grau de satisfação dos pacientes (ag3,8:bpcs3,9). CONCLUSÃO: Embora com incidência maior de bradicardia (23,8%), o bloqueio permitiu ressecar tumorações de até 348 cm3 com menor custo e sem apresentar lesões laringotraqueais, presentes em 51% dos pacientes submetidos à AG.

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Pavlović, Miloš D. "Regarding “Tumescent technique without epinephrine for endovenous laser therapy and serum lidocaine concentration”." Journal of Vascular Surgery: Venous and Lymphatic Disorders 3, no. 3 (2015): 345. http://dx.doi.org/10.1016/j.jvsv.2015.03.006.

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Ortiz, Michele Purper, Maria Celoni de Mello Godoy, Rochelle Silveira Schlosser, et al. "Effect of endovenous lidocaine on analgesia and serum cytokines: double-blinded and randomized trial." Journal of Clinical Anesthesia 35 (December 2016): 70–77. http://dx.doi.org/10.1016/j.jclinane.2016.07.021.

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Pannier, F., E. Rabe, J. Rits, A. Kadiss, and U. Maurins. "Endovenous laser ablation of great saphenous veins using a 1470 nm diode laser and the radial fibre – follow-up after six months." Phlebology: The Journal of Venous Disease 26, no. 1 (2010): 35–39. http://dx.doi.org/10.1258/phleb.2010.009096.

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Background Endovenous laser ablation (EVLA) is an efficient method to treat insufficient great saphenous veins (GSV) with high occlusion rates.1–5 Most studies used 810, 940 or 980 nm diode lasers and a bare fibre.1,2,6 Moderate postoperative pain and bruising are frequent findings.2,6 Laser systems with higher wavelengths like 1470 nm with a higher absorption in water show less pain and bruising after the procedure.7–9 A newly-developed fibre (radial fibre, Biolitec) emits the laser energy radially around the tip directly into the venous wall contrary to the bare fibre.9 The aim of this study was to demonstrate the outcome and side-effects after EVLA of GSV with a 1470 nm diode laser (Ceralas E, Biolitec) by using the radial fibre. Methods Non-randomized, prospective study including 50 unselected limbs of 50 patients with a duplex sonographically verified incompetent GSV. EVLA was performed with a 1470 nm diode laser (Ceralas E, Biolitec) and a radial fibre. In the same session all insufficient tributaries were treated by phlebectomy. Tumescent local anaesthesia with 0.05% lidocaine was applied perivenously. Laser treatment was carried out in a continuous mode with a power of 15 W. Compression stockings (30 mmHg) were applied for one month. Postinterventional checkups took place one, 10, 30 days and six months after the procedure. Results Three patients were lost to follow-up. The average linear endovenous energy density (LEED) was 90.8 J/cm vein (SD 35.3). At the six month follow-up all treated veins remained occluded and no new reflux in the treated segments occurred. No recurrent varicose veins had occurred so far. No severe complications such as deep venous thrombosis could be detected. In four patients at 30 days and three patients at six months local paresthesia occurred in the region of EVLA. Forty-four percent of patients did not have any pain after the treatment and 50% did not take any analgesic tablets at any time after the procedure. Postoperative ecchymoses in the track of the treated GSV was rare. In 80% of the limbs, no ecchymoses was observed after the treatment. Conclusion EVLA of GSV with a radially emitting laser fibre by using a 1470 nm diode laser is a safe and efficient treatment option.

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Rangel, Felipe Porto, Claudia Marquez Simões, and José Otávio Costa Auler Junior. "Anestesia no paciente oncológico." Revista de Medicina 99, no. 1 (2020): 40–45. http://dx.doi.org/10.11606/issn.1679-9836.v99i1p40-45.

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Introdução: A anestesia no paciente oncológico representa um desafio sob vários aspectos: pacientes complexos, com diversas comorbidades e, muitas vezes, submetidos a tratamentos adjuvantes. O tratamento cirúrgico é o tratamento de primeira linha em grande parte dos casos oncológicos e a anestesia é uma etapa essencial para viabilizar este tratamento. O uso de diferentes agentes e técnicas anestésicas hoje é visto como um dos potenciais fatores que podem vir a influenciar o desfecho oncológico. Revisamos alguns dos novos conceitos que têm surgido na literatura, referentes aos cuidados anestésicos perioperatórios e a evolução desta população. Métodos: Estudo bibliográfico narrativo e exploratório. Realizada pesquisa nos bancos de dados Medline e SciELO, utilizando os termos (((anesthesia) OR (anaesthesia)) AND (cancer)) até novembro de 2019 e 44 estudos foram utilizados. Resultados: Os estudos discutem o papel específico de diversos agentes anestésicos, principalmente agentes hipnóticos endovenosos, inalatórios e opioides, além de abordarem as possíveis diferenças entre as técnicas anestésicas. Além dos agentes anestésicos propriamente ditos, o papel de outros agentes frequentemente utilizados no período perioperatório foram incluídos. Conclusões: Técnicas de anestesia regional ainda necessitam ser mais estudadas, mas podem trazer benefícios para esta população auxiliando no controle álgico perioperatório, reduzindo o consumo de opioides e a inflamação desencadeada pela resposta ao estresse. Ainda não há evidências suficientes para modificação dos agentes e técnicas utilizadas na anestesia, mas existem alguns potenciais benefícios sinalizados para o uso de anestesia venosa, técnicas de analgesia multimodal poupadora de opioides e, até mesmo, o uso de certos agentes como a lidocaína e o propofol. Poucas evidências clínicas respaldam o uso de anestesia totalmente livre de opioides com o objetivo de reduzir a recorrência tumoral e otimizar o desfecho do paciente oncológico, mas o assunto está sendo amplamente pesquisado e brevemente haverá mais novidades e evidências que poderão redirecionar a conduta anestésica perioperatória.

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Bukina, O. V., and A. A. Sinitsin. "Anesthesia in outpatient phlebology practice." Ambulatory surgery: hospital-replacing technologies, no. 1-2 (June 20, 2018): 52–56. http://dx.doi.org/10.21518/1995-14772018-1-2-52-56.

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Tumescent and/or conductive anaesthesia is the most frequently performed procedure to anesthetize the thermal types of surgical interventions, mini-phlebectomy and stripping of subcutaneous veins in outpatient settings. These interventions have become a common outpatient procedure almost everywhere, which made the issue of local anaesthesia more sensitive over the past 5 years in Russia. The aim is to compare the efficacy, safety and comfort when injecting various anaesthetic solutions to relieve pain during endovenous laser obliteration/radio frequency catheter ablation, stripping of the subcutaneous veins and mini-phlebectomy. Searching method. We searched for original articles in PubMed, in the archives of «Phlebology» and «Angiology and Vascular Surgery» journals issued for the period between 2001 and November 2018 and the search for official instructions in the state register of medicinal products. Selection criteria. We included all comparative studies: randomized and non-randomized, in which pain was assessed both during injection of a tumescent solution before EVLO and/or mini-phlebectomy and during surgery, as well as systematic reviews and monographs. Data analysis. In total, we identified 9 studies: 7 randomized and 2 non-randomized, one systematic review and two monographs. The advantage of a buffered solution over unbuffered one in terms of reducing pain during injection is revealed in three randomized, one simple comparative study and on the basis of systematic review data. A great efficacy of combining tumescent anaesthesia with a femoral nerve blockade, which was equivalent to spinal anaesthesia, was found in 4 randomized trials, two of which were double-blind, and one non-randomized. In addition, a smaller degree of motor block was reported after blocking the femoral nerve in comparison with spinal anaesthesia. In one randomized trial in which pain was assessed using cold and warm solutions, no significant differences in pain were observed either during or after surgery. In order to prepare a tumescent solution, lidocaine, prilocaine and mepivacaine were used at concentrations ranging from 0.028% to 0.2%; the advantages of higher concentrations over the lower ones have not been revealed. No adverse reactions and complications of anaesthesia have been reported in the studies, except for one where methaemoglobinemia of mild degree was detected in a small number of patients when using 0.2% prilocaine. The conclusion. Local anaesthesia, namely, conductive and tumescent anaesthesia, is an effective and safe anaesthesia method in outpatient surgery. Even very low concentrations of anaesthetic solutions are effective for tumescent anaesthesia. The use of buffered solutions increases significantly patient comfort during the injection. The combination of tumescent anaesthesia and femoral nerve block increases the effectiveness of anaesthesia. The femoral nerve block has significant advantages in comparison with spinal anaesthesia in terms of safety.

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Guillén Ramírez, Nayely Teresa, Miguel Jimenez Olvera, Marcos Antonio Morales Aguila, et al. "Dexmedetomidina versus lidocaína endovenosa en el tratamiento del dolor irruptivo y la funcionalidad en pacientes con canal lumbar estrecho." Revista de la Sociedad Española del Dolor, 2018. http://dx.doi.org/10.20986/resed.2018.3656/2018.

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Pelegrine, Ana Carolina Martins, Laura de Oliveira Nascimento, and Viviane Lucia Beraldo de Araújo. "Nanostructured lipid carriers with ultra purified lipids for sustained release of intravenous lidocaine." Revista dos Trabalhos de Iniciação Científica da UNICAMP, no. 26 (December 4, 2018). http://dx.doi.org/10.20396/revpibic262018110.

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Lidocaine (LDC) is a local anesthetic that can be used for post-surgical or cancer related pain, via intravenous infusion or bolus. An alternative to maintain drug plasma levels are the sustained release carriers, whereas nanostructured lipid carriers (NLCs) stand out; they have biocompatibility, low toxicity, reproducibility and high efficiency in the transport of hydrophobic drugs.This work aims to study the solubility parameter of the LDC pre formulation in several ultra-purified lipids, compatible with the endovenous route, and to formulate NLCs based on these lipids for LDC encapsulation.

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Journal articles on the topic 'Lidocaína endovenosa'

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