Academic literature on the topic 'Life change events Physiological effect'

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Journal articles on the topic "Life change events Physiological effect"

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Glaeser, Sharon S., Katie L. Edwards, Nadja Wielebnowski, and Janine L. Brown. "Effects of physiological changes and social life events on adrenal glucocorticoid activity in female zoo-housed Asian elephants (Elephas maximus)." PLOS ONE 15, no. 11 (November 6, 2020): e0241910. http://dx.doi.org/10.1371/journal.pone.0241910.

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Ensuring good health and welfare is an increasingly important consideration for conservation of endangered species and includes breeding of individuals managed under human care. Understanding how factors in the captive environment affect individual animal wellbeing can be aided by long-term monitoring of biological functioning. This study involved longitudinal assessments (4 to 28 years) of reproductive and adrenal hormones in zoo-housed female Asian elephants (Elephas maximus) (age range 4 to ~71 years) to elucidate patterns in adrenal glucocorticoid (GC) activity in association with reproduc
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Bernhardt, Joey R., Mary I. O'Connor, Jennifer M. Sunday, and Andrew Gonzalez. "Life in fluctuating environments." Philosophical Transactions of the Royal Society B: Biological Sciences 375, no. 1814 (November 2, 2020): 20190454. http://dx.doi.org/10.1098/rstb.2019.0454.

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Variability in the environment defines the structure and dynamics of all living systems, from organisms to ecosystems. Species have evolved traits and strategies that allow them to detect, exploit and predict the changing environment. These traits allow organisms to maintain steady internal conditions required for physiological functioning through feedback mechanisms that allow internal conditions to remain at or near a set-point despite a fluctuating environment. In addition to feedback, many organisms have evolved feedforward processes, which allow them to adjust in anticipation of an expect
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LESERMAN, J., J. M. PETITTO, H. GU, B. N. GAYNES, J. BARROSO, R. N. GOLDEN, D. O. PERKINS, J. D. FOLDS, and D. L. EVANS. "Progression to AIDS, a clinical AIDS condition and mortality: psychosocial and physiological predictors." Psychological Medicine 32, no. 6 (August 2002): 1059–73. http://dx.doi.org/10.1017/s0033291702005949.

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Background. The primary aim of this study is to examine prospectively the association of stressful life events, social support, depressive symptoms, anger, serum cortisol and lymphocyte subsets with changes in multiple measures of human immunodeficiency virus (HIV) disease progression.Methods. Ninety-six HIV-infected gay men without symptoms or anti-retroviral medication use at baseline were studied every 6 months for up to 9 years. Disease progression was defined in three ways using the Centers for Disease Control (CDC) classifications (e.g. AIDS, clinical AIDS condition and mortality). Cox r
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Meylan, Sandrine, Donald B. Miles, and Jean Clobert. "Hormonally mediated maternal effects, individual strategy and global change." Philosophical Transactions of the Royal Society B: Biological Sciences 367, no. 1596 (June 19, 2012): 1647–64. http://dx.doi.org/10.1098/rstb.2012.0020.

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A challenge to ecologists and evolutionary biologists is predicting organismal responses to the anticipated changes to global ecosystems through climate change. Most evidence suggests that short-term global change may involve increasing occurrences of extreme events, therefore the immediate response of individuals will be determined by physiological capacities and life-history adaptations to cope with extreme environmental conditions. Here, we consider the role of hormones and maternal effects in determining the persistence of species in altered environments. Hormones, specifically steroids, a
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Cohen, Miri, Liora Sklair-Tavron, and Shimon Pollack. "The Association of Forskolin-Stimulated Cyclic AMP Levels in Peripheral Blood Mononuclear Cells of Healthy People with Depressive Mood and Sense of Coherence." Journal of Psychophysiology 18, no. 4 (January 2004): 177–83. http://dx.doi.org/10.1027/0269-8803.18.4.177.

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Abstract: Background: Depressive mood exerts a suppressive effect on immune functions, mediated through neuro-immune processes. Research suggests a protective effect of sense of coherence (SOC) on psychological and physical health in face of stressful life events. Cyclic adenosine monophosphate (cAMP) is a cellular second messenger that is coupled to certain receptors expressed on peripheral blood mononuclear cells (PBMC). By interfering with the neuro-endocrine-immune axis, depressive mood may induce changes in intracellular cAMP levels in PBMC. Aims of study: To examine a possible associatio
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Martinez, J., and S. Merino. "Host-parasite interactions under extreme climatic conditions." Current Zoology 57, no. 3 (June 1, 2011): 390–405. http://dx.doi.org/10.1093/czoolo/57.3.390.

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Abstract The effect that climatic changes can exert on parasitic interactions represents a multifactor problem whose results are difficult to predict. The actual impact of changes will depend on their magnitude and the physiological tolerance of affected organisms. When the change is considered extreme (i.e. unusual weather events that are at the extremes of the historical distribution for a given area), the probability of an alteration in an organisms’ homeostasis increases dramatically. However, factors determining the altered dynamics of host-parasite interactions due to an extreme change a
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Uddin, Md Nagim, Tutul Kumar Saha, Myiesha Rayzil Hossain, SM Fakrul Islam, and Zakir Hossain. "Constraints to climate change adaptation and livelihood challenges: perspectives from the Sundarbans fishers' community in Bangladesh." Asian Journal of Medical and Biological Research 8, no. 2 (June 26, 2022): 103–14. http://dx.doi.org/10.3329/ajmbr.v8i2.60083.

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Fishers' are first-line observers of changes in the Sundarbans region and are among the first to be affected by the changes that occurred. In the Sundarbans fishers' communities, transformations of society have always been a part of life. In contrast, environmental changes were always interim and reversible, allowing them to understand and identify with the Sundarbans ecosystems as food and life providers. In this study, fishers' observations on climate change impacts and their livelihoods were compiled and analysed using a structured questionnaire in accordance with the tenets of grounded the
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van Halem, Sjoerd, Eeske van Roekel, Lara Kroencke, Niclas Kuper, and Jaap Denissen. "Moments that Matter? On the Complexity of using Triggers Based on Skin Conductance to Sample Arousing Events within an Experience Sampling Framework." European Journal of Personality 34, no. 5 (September 2020): 794–807. http://dx.doi.org/10.1002/per.2252.

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To sample situations that are psychologically arousing in daily life, we implemented an experience sampling strategy in which 82 Dutch young adults ( Mage = 20.73) were triggered based on random time intervals and based on physiological skin conductance scores across a period of 5 days. When triggered, participants had to fill in short surveys on affect, situational characteristics and event characteristics on their smartphone. We found theoretically expected relationships between the skin conductance signal on the one hand and self–reported arousal and positive energy (e.g. energetic and enth
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Glaeser, Sharon S., Katie L. Edwards, Stephen Paris, Candace Scarlata, Bob Lee, Nadja Wielebnowski, Shawn Finnell, Chaleamchat Somgird, and Janine L. Brown. "Characterization of Longitudinal Testosterone, Cortisol, and Musth in Male Asian Elephants (Elephas maximus), Effects of Aging, and Adrenal Responses to Social Changes and Health Events." Animals 12, no. 10 (May 23, 2022): 1332. http://dx.doi.org/10.3390/ani12101332.

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The conservation of endangered species and sustainability of managed populations requires considerations to ensure the health and welfare of individuals. Male elephants experience a biological phenomenon called “musth”, which is characterized by increased testosterone production, temporal gland secretion and urine dribbling, heightened aggression and sexual behavior, and therefore can pose unique challenges for human safety and animal welfare. This study characterized longitudinal (9 to 22 years) patterns of circulating testosterone and cortisol in relation to musth in four adult Asian elephan
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Gunderson, Alex R., Amélie Fargevieille, and Daniel A. Warner. "Egg incubation temperature does not influence adult heat tolerance in the lizard Anolis sagrei." Biology Letters 16, no. 1 (January 2020): 20190716. http://dx.doi.org/10.1098/rsbl.2019.0716.

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Extreme heat events are becoming more common as a result of anthropogenic global change. Developmental plasticity in physiological thermal limits could help mitigate the consequences of thermal extremes, but data on the effects of early temperature exposure on thermal limits later in life are rare, especially for vertebrate ectotherms. We conducted an experiment that to our knowledge is the first to isolate the effect of egg (i.e. embryonic) thermal conditions on adult heat tolerance in a reptile. Eggs of the lizard Anolis sagrei were incubated under one of three fluctuating thermal regimes th
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Dissertations / Theses on the topic "Life change events Physiological effect"

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Price, Simani Mohapatra. "The effect of rumination on beliefs about adjustment to future negative life events." Thesis, This resource online, 1993. http://scholar.lib.vt.edu/theses/available/etd-08182009-040525/.

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Shiau, Shujen. "The mediating effect of maternal-child coping behaviors on child adaptational outcome : an ecological approach /." Thesis, Connect to this title online; UW restricted, 1989. http://hdl.handle.net/1773/7349.

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Graham, Neil M. H. (Neil Murray Hamilton). "Psychosocial factors in the epidemiology of acute respiratory infection." 1987. http://web4.library.adelaide.edu.au/theses/09MD/09mdg741.pdf.

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Graham, Neil M. H. (Neil Murray Hamilton). "Psychosocial factors in the epidemiology of acute respiratory infection." Thesis, 1987. http://hdl.handle.net/2440/38315.

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Matson, Liana M. "Investigating reactivity to incentive downshift as a correlated response to selection for high alcohol preference and a determinant of rash action and alcohol consumption." Thesis, 2014. http://hdl.handle.net/1805/5964.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Losing a job or a significant other are examples of incentive shifts that result in negative emotional reactions. The occurrence of negative life events is associated with increased drinking, and alleviation of negative emotions has been cited as a drinking motive for individuals with problematic drinking patterns (Keyes et al., 2011; Adams et al., 2012). Further, there is evidence that certain genotypes drink alcohol in response to stressful negative life events (Blomeyer et al., 2008; Covault et al., 2007). It is possible that shar
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Friedman, Beverly. "The effect of contextual and historical factors on post-traumatic stress in car-hijacking." Thesis, 2014. http://hdl.handle.net/10210/12075.

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Kotzé, Esté. "Die algemene weerstandsbronne van vroue wie se mans buite-egtelike verhoudings gehad het." Thesis, 2012. http://hdl.handle.net/10210/7429.

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M.A.<br>This study uses the salutogenic model as a departure point to focus on the sense of coherence (SOC) of women who had to overcome a crisis. Stressors come in many forms but this study focuses specifically on the husband's extramarital affair. After (or during) the initial shock the woman has to make a decision regarding her marriage. Women were considered in regard to the decisions they made, namely to stay in the marriage or to leave it. The first hypothesis stated that the SOC of the women who decided to leave the relationship would be higher than that of the other group. The second h
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Books on the topic "Life change events Physiological effect"

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Quand les sombres nuages persistent: Conseils du coeur à ceux qui vivent des moments difficiles et à ceux qui les aiment. Boucherville, Quebec: De Mortagne, 2011.

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Buchwald, Petra, Tobias Ringeisen, and Kathleen A. Moore. Stress and anxiety: Application to education and health. Berlin: Logos Verlag Berlin, 2011.

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Buchwald, Petra, Kathleen A. Moore, and Krzysztof Kaniasty. Stress and anxiety: Application to economic hardship, occupational demands, and developmental challenges. Berlin: Logos, 2012.

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Buchwald, Petra, Kathleen A. Moore, Krzysztof Kaniasty, and Albert Sesé. Stress and anxiety: Applications to health and well-being, work stressors, and assessment. Berlin: Logos Verlag Berlin, 2013.

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Deschênes, Olivier. Extreme weather events, mortality and migration. Cambridge, Mass: National Bureau of Economic Research, 2007.

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The Ripple Effect: Our Harvest. Onjinjinkta Publishing, 1999.

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Eadie, Betty J. The Ripple Effect: Our Harvest. Onjinjinkta Publishing, 1999.

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Grace, Annie. This naked mind: Control alcohol, find freedom, discover happiness & change your life. 2018.

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Davis, Marli. Quit Smoking and Stay Quit: Discover a New Way to Change (New Life Guides, Helping People to Change). MCJ Global Resources, 2003.

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1961-, Buchwald Petra, Ringeisen Tobias, and Eysenck Michael W, eds. Stress and anxiety: Application to life span development and health promotion. Berlin: Logos, 2008.

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Book chapters on the topic "Life change events Physiological effect"

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Dunsmoor, Joseph E., and Marijn C. W. Kroes. "Emotion–Memory Interactions." In Neuroscience of Enduring Change, 132–62. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190881511.003.0006.

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Emotional events are better remembered with more vividness and confidence than everyday occurrences. This prioritization of emotional events in memory can be helpful by ensuring that we remember important information associated with meaningful events. But persistent and intrusive memories of negative experiences presents a burden to daily life, exemplified in anxiety and stress disorders, such as posttraumatic stress disorder. Here, we describe emerging cognitive neuroscience research detailing how emotion shapes learning and memory. This research is framed in a historical context of pioneering studies in laboratory animals on Pavlovian fear conditioning and the role of stress and arousal on memory formation. Translating advances in the neuroscience of learning and memory from rodents to humans has opened the way for several lines of research that may ultimately lead to a better understanding and innovative treatments for mental health disorders. This includes new insights on how memory might be persistently attenuated so as to diminish the psychological and physiological effects of unwanted emotional memories.
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West-Eberhard, Mary Jane. "Heterochrony." In Developmental Plasticity and Evolution. Oxford University Press, 2003. http://dx.doi.org/10.1093/oso/9780195122343.003.0019.

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Heterochrony is evolutionary change in the timing of expression of a phenotype trait, that transfers expression of the trait from one life stage or behavioral or physiological phase to another—”the shifting of characters from one part of an ontogeny to another” (Valentine, 1977b, p. 260) or simply “the displacement of characters in time” (Gould, 1977, p. 225). A clear fossil example occurs in monograptids, where there is a temporal shift in the onset of a modified morphology, a life-history modification that is recorded in the structure of the body (figure 13.1). Heterochrony can occur at any level of organization, including the molecular level, where evolutionary changes in the timing of gene expression have been demonstrated, for example, in echinoids and a fibronectin gene of amphibians (Collazo, 1994). Some recent authors (e.g., McKinney and McNamara, 1991; Reilly et al., 1997) define heterochrony as any change in the timing of regulatory events. Most novel traits qualify as heterochrony by this regulatory-timing definition, since virtually all evolutionary change involves change in the timing of developmental events. This regulatorytiming definition of heterochrony leads to a classification of evolutionary change termed panheterochrony by McKinney and McNamara (1991)—a classification of evolutionary transitions that lumps all evolutionary change under the heading of heterochrony. “Because all developmental events occur along a time line, any significant change is likely to result in a heterochrony at some level” (Raff, 1992, p. 211). As expressed by Barbara McClintock in a staff meeting at Cold Spring Harbor Laboratories, “If I could control the time of gene action, I could cause a fertilized snail egg to develop into an elephant. Their biochemistries are not all that different; it's simply a matter of timing”. I will adhere to a classification that divides the effects of regulatory change into their different kinds of effects on phenotypes, in keeping with the general emphasis on phenotypes in this book.
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Tatar, Marc. "Senescence." In Evolutionary Ecology. Oxford University Press, 2001. http://dx.doi.org/10.1093/oso/9780195131543.003.0015.

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At all taxonomic levels, there exists tremendous variation in life expectancy. A field mouse Peromyscus may live 1.2 years, while the African elephant may persist for 60 years, and even a mousesized bat such as Corynorhinus rafinesquei lives a healthy 20 years (Promislow 1991). Part of this variance is caused by differences in ecological risks, rodents being perhaps the most susceptible to predation, and to vagaries of climate and resources. Another portion is caused by differences in senescence, the intrinsic degeneration of function that produces progressive decrement in age-specific survival and fecundity. Senescence occurs in natural populations, where it affects life expectancy and reproduction as can be seen, for instance, from the progressive change in age-specific mortality and maternity of lion and baboon in East Africa. The occurrence of senescence and of the widespread variation in longevity presents a paradox: How does the age-dependent deterioration of fitness components evolve under natural selection? The conceptual and empirical resolutions to this problem will be explored in this chapter. We shall see that the force of natural selection does not weigh equally on all ages and that there is therefore an increased chance for genes with late-age-deleterious effects to be expressed. Life histories are expected to be optimized to regulate intrinsic deterioration, and in this way, longevity evolves despite the maladaptive nature of senescence. From this framework, we will then consider how the model is tested, both through studies of laboratory evolution and of natural variation, and through the physiological and molecular dissection of constraints underlying trade-offs between reproduction and longevity. As humans are well aware from personal experience, performance and physical condition progressively deteriorate with adult age. And in us, as well as in many other species, mortality rates progressively increase with cohort age. Medawar (1955), followed by Williams (1957), stated the underlying assumption connecting these events: Senescent decline in function causes a progressive increase in mortality rate. Although mortality may increase episodically across some age classes, such as with increases in reproductive effort, we assume that the continuous increase of mortality across the range of adult ages represents our best estimate of senescence.
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de Berker, David. "Hair and nail disorders." In Oxford Textbook of Medicine, edited by Roderick J. Hay, 5724–31. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0562.

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Nails grow continuously throughout life, except after exceptional physiological or traumatic events when they are shed. All other less disruptive influences result in changes in the colour, thickness, texture, and growth of nails, and may also affect the periungual tissues. The most common local diseases affecting the nail are psoriasis, fungal nail infections, periungual eczema, and viral warts. Trauma is a common cause of changes in toenails. Disease can affect hair growth by direct action on the follicle or by indirect effects sustained through generalized physiological disturbance. Clinicians might be asked to assess specific diseases of the scalp with implications for hair growth, or specifically to address pathological patterns of hair growth where there may be underlying systemic disease. Common diseases of the scalp include psoriasis, eczema, fungal infection, alopecia areata, and the scarring alopecias.
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Shafer, Krystle, and Marie R. Baldisseri. "Neurocritical Care in Pregnancy." In Neurocritical Care, edited by Samuel A. Tisherman and Sara Hefton, 247–55. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199375349.003.0023.

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Pregnancy results in physiologic changes that bring added stress to the body. Changes in cardiovascular hemodynamics, respiratory physiology, coagulation profile, hormonal concentrations, and endothelial function can result in the perfect storm for cerebrovascular dysfunction. Cerebrovascular disorders of pregnancy can be grossly simplified to disorders that arise from thrombosis, hemorrhage, and/or hypertension. Care of these patients become more complex when considering the effects of therapy on the fetus. The age of the fetus comes into play as well as pharmacologic agents that cross the placenta and may potentially harm the fetus. Ultimately, the priority for the clinician is to provide life-saving care to the patient even if it is at the expense of the fetus. In rare cases where despite best medical management practices the patient develops brain death or is vegetative, the decision to continue life support to allow further development of the fetus becomes an ethically complex situation.
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Kukulska-Hulme, Agnes. "Language Change." In Language and Communication. Oxford University Press, 1999. http://dx.doi.org/10.1093/oso/9780195108385.003.0009.

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• Are computer applications changing our language? • Why do some people reject technology? • Are adults willing to change their language? • Do other cultures want to borrow English computing terms? • Is our knowledge of word meanings out of date? . . . In this chapter on language change, we address these questions first by examining the reasons for change and looking at the various types of change that can occur. We then focus on developments in the language of adults (life-long language learning) and on how language is organized in the minds of speakers. We consider people’s expectations with regard to meanings as well as the process of acquiring new words and meanings. The final part of the chapter deals with the issue of borrowing words from other languages. No one really knows why languages change over time, though a number of possible explanations have been put forward concerning specific instances of change. Historical events can sometimes provide explanations, when new contact or loss of contact between groups of people is eventually reflected in the word stock or sounds of a language. It is interesting to speculate whether electronic contact (e.g., through the Internet) might have the same degree of power to change languages over time. Certainly, in that environment, as in the “real world,” social forces can be observed: Borrowing words from another language and integrating them into one’s own can be part of a process of wanting to imitate another culture—especially one that is seen to be more fashionable or more technologically advanced. If new objects, ideas, and processes have to be named, new words will appear; similarly, old ones will fall out of use. Technological advancements contribute to these needs. They also create new human communication environments, which require new forms of text or speech, which in turn have an effect on the language to be used.
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Bonura, Sandra E. "Introduction." In Light in the Queen's Garden. University of Hawai'i Press, 2017. http://dx.doi.org/10.21313/hawaii/9780824866440.003.0001.

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Great historical events often accompany great forces of nature: a hurricane, a tsunami, an avalanche. Traced back to their origins, such natural cataclysms start as a gentle breeze, a single drop of rain, a small pebble falling. They appear harmless, but trigger life-changing events. Similarly, a swath of Hawaiian history can be traced directly to an unassuming woman from Ohio who set into motion a series of events that would ultimately effect social change for Hawaiian women....
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Fink MD, Max. "What Is Electroconvulsive Therapy?" In Electroconvulsive Therapy. Oxford University Press, 2010. http://dx.doi.org/10.1093/oso/9780195365740.003.0005.

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Electroconvulsive therapy (ECT) is an effective medical treatment for severe and persistent psychiatric disorders. It relieves de pressed mood and thoughts of suicide, as well as mania, acute psychosis, delirium, and stupor. It is usually applied when medications have given limited relief or their side effects are intolerable. Electroconvulsive therapy is similar to a surgical treatment. It requires the specialized skills of a psychiatrist, an anesthesiologist, and nurses. The patient receives a short-acting anesthetic. While the patient is asleep, the physician, following a prescribed procedure, induces an epileptic seizure in the brain. By making sure that the patient’s lungs are filled with oxygen, the physician precludes the gasping and difficult breathing that accompany a spontaneous epileptic fit. By relaxing the patient’s muscles with chemicals and by inserting a mouth guard (not unlike those used in sports), the physician prevents the tongue biting, fractures, and injuries that occasionally occur in epilepsy. The patient is asleep, and so experiences neither the painful effects of the stimulus nor the discomforts of the seizure. The physiological functions of the body, such as breathing, heart rate, blood pressure, blood oxygen concentration, and degree of motor relaxation, are monitored, and anything out of the ordinary is immediately treated. Electroconvulsive therapy relieves symptoms more quickly than do psychotropic drugs. A common course of ECT consists of two or three treatments a week for two to seven weeks. To sustain the recovery, weekly or biweekly continuation treatments, either ECT or medications, are often administered for four to six months. If the illness recurs, ECT is prescribed for longer periods. The duration and course of ECT are similar to those of the psychotropic medicines frequently used for the same conditions. Electroconvulsive therapy has been used safely to treat emotional disorders in patients of all ages, from children to the elderly, in people with debilitating physical illnesses, and in pregnant women. Emotional disorders may be of short or long duration; they may be manifest as a single episode or as a recurring event. Electroconvulsive treatment is an option when the emotional disorder is acute in onset; when changes in mood, thought, and motor activities are pronounced; when the cause is believed to be biochemical or physiological; when the condition is so severe that it interferes with the patient’s daily life; or when other treatments have failed.
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Merhan, Oguz. "Biochemistry and Antioxidant Effects of Melatonin." In Melatonin - Recent Updates [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.106260.

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Melatonin (N-acetyl-5-methoxy-tryptamine) is a hormone taking place in many biological and physiological processes, such as reproduction, sleep, antioxidant effect, and circadian rhythm (biological clock), and is a multifunctional indolamine compound synthesized mainly from the metabolism of tryptophan via serotonin in the pineal gland. Melatonin, which is a hormone synthesized from the essential amino acid tryptophan, is substantially secreted from the pineal gland between the cerebral hemispheres found in the mammalian brain. In addition to this, it is also produced in the cells and tissues, such as the gastrointestinal system, gall, epithelial hair follicles, skin, retina, spleen, testis, salivary glands, bone marrow, leukocytes, placenta, and thrombocytes. It plays a role in many physiological events, such as synchronizing circadian rhythms, reproduction, fattening, molting, hibernation, and change of pigment granules, preserving the integrity of the gastrointestinal system with an anti-ulcerative effect in tissues and organs from which it is produced. Melatonin is also a powerful antioxidant and anti-apoptotic agent that prevents oxidative and nitrosative damage to all macromolecules due to its ability to form in metabolic activities, directly excrete toxic oxygen derivatives, and reduce the formation of reactive oxygen and nitrogen species. In this book chapter, we will explain the structure, synthesis, metabolism, and antioxidant effects of the melatonin hormone.
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Fernandes, Melissa, Vera Bernardino, Anna Taulaigo, Jorge Fernandes, Ana Lladó, and Fátima Serrano. "Systemic Lupus Erythematosus Pregnancy." In Lupus - Need to Know. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99008.

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Systemic Lupus Erythematosus (SLE) is an autoimmune disease of unknown etiology that often affects women during childbearing age. Pregnant women with SLE are considered high-risk patients, with pregnancy outcomes being complicated by high maternal and fetal mortality and morbidity. Obstetric morbidity includes preterm birth, fetal growth restriction (FGR), and neonatal lupus syndromes. Active SLE during conception is a strong predictor of adverse pregnancy outcomes and exacerbations of disease can occur more frequently during gestation. Therefore, management of maternal SLE should include preventive strategies to minimize disease activity and to reduce adverse pregnancy outcomes. Patients with active disease at time of conception have increased risk of flares, like lupus nephritis, imposing a careful differential diagnosis of pre-eclampsia, keeping in mind that physiological changes of pregnancy may mimic a lupus flare. Major complications arise when anti-phospholipid antibodies are present, like recurrent pregnancy loss, stillbirth, FGR, and thrombosis in the mother. A multidisciplinary approach is hence crucial and should be initiated to all women with SLE at childbearing age with an adequate preconception counseling with assessment of risk factors for adverse maternal and fetal outcomes with a tight pregnancy monitoring plan. Although treatment choices are limited during pregnancy, prophylactic anti-aggregation and anticoagulation agents have proven beneficial in reducing thrombotic events and pre-eclampsia related morbidity. Pharmacological therapy should be tailored, allowing better outcomes for both the mother and the baby. Immunosuppressive and immunomodulators, must be effective in controlling disease activity and safe during pregnancy. Hydroxychloroquine is the main therapy for SLE due to its anti-inflammatory and immunomodulatory effects recommended before and during pregnancy and other immunosuppressive drugs (e.g. azathioprine and calcineurin inhibitors) are used to control disease activity in order to improve obstetrical outcomes. Managing a maternal SLE is a challenging task, but an early approach with multidisciplinary team with close monitoring is essential and can improve maternal and fetal outcomes.
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Conference papers on the topic "Life change events Physiological effect"

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You, Jun, Clare E. Yellowley, Henry J. Donahue, and Christopher R. Jacobs. "Physiological Levels of Substrate Deformation Are Less Stimulatory to Bone Cells Compared to Fluid Flow." In ASME 1999 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/imece1999-0427.

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Abstract It is believed that bone cells can sense mechanical loading and alter bone external shape and internal structure to efficiently support the load bearing demands placed upon it. However, the mechanism by which bone cells sense and respond to their mechanical environment is still poorly understood. In particular, the load-induced signals to which bone cells respond, e.g. fluid flow, substrate deformation, electrokinetic effects etc., are unclear. Furthermore, there are few studies focused on the effects of physiological strain (strain &amp;lt; 0.5%, Burr, 1996; Owan, 1997) on bone cells
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Uitterhoeve, Wendie, and Melcher Zeilstra. "Differences in Workload of Both Skippers and Pilots Due to Changes in Environmental Bank Lights." In Applied Human Factors and Ergonomics Conference. AHFE International, 2022. http://dx.doi.org/10.54941/ahfe100725.

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In the case a sea harbour is located in an inland area, seagoing vessels have to sail a part of their journey in inland waterways. On these approach channels the inland water regulation prescribes specific bridge equipment. Inland vessels fulfil this regulation, the seagoing vessels not, but get dispensation with a pilot on board. The question arises how differences in working strategy (resulting from different ship characteristics and equipment) express in differences in workload. The effect of changes in environmental bank lights (puddle lights) on both inland skippers and pilots is studied
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Chiu, Wei-Che, Yared Alemu, Bryan Lynch, Shmuel Einav, Marvin Slepian, and Danny Bluestein. "Comparative Studies of Axial Ventricular Assist Devices (VAD) and the Effect of Outflow Cannulation." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14102.

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Congestive heart failure has reached epidemic proportions in the United States with more than 5.7 million patients suffering from it annually ( 1). Due to the limited availability of donor hearts, patients in their late stage heart failure who may require cardiac transplantation are dying while waiting for a matched heart. Mechanical circulatory support devices (MCS), such as ventricular assist devices (VAD), are utilized as a bridge to transplantation, and recently as destination therapy for extending the life of these patients. Continuous-flow VAD offer a surgical advantage over older genera
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Camilleri, Lawrence, Arthur Watson, Yan Liu, and Mohammed El-Gindy. "Keep Your ESPs Running: Case Studies Exhibiting a Holistic Methodology for Run-Life Improvement." In SPE Gulf Coast Section Electric Submersible Pumps Symposium. SPE, 2021. http://dx.doi.org/10.2118/204483-ms.

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Abstract Build a more robust ESP or reduce the stress it endures? Run-life improvement requires finding the right balance to suit the local well conditions and economics. Utilizing key case studies, the paper examines how operational stress caused by low flow rates can be avoided with the correct utilization of instrumentation, surveillance, and automation thereby providing practical solutions for extending the run life of already installed ESPs. The method starts with an extensive review of ESP failure mechanisms and their causes, supported by case studies and pictures illustrating the sympto
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GOLYASH, Iryna. "THE WAR AND HAPPINESS: SOCIO-ECONOMIC ASPECTS." In Proceedings of The Third International Scientific Conference “Happiness and Contemporary Society”. SPOLOM, 2022. http://dx.doi.org/10.31108/7.2022.15.

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Ukraine has felt the impact of strong force, which has affected the level of happiness in the country. The circumstances were military actions which was provoked by the aggression of the Russian Federation. A whole generation of people knew about the war only from historical sources and had no previous experience of survival. During the war, basic physiological needs became a priority for the civilian population of Ukraine: security, water, food, heat, sleep, medicine. All other needs of a higher order have ceased, or become to be inconsiderable. The war did not make people happy, but it chang
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Prasad, P. Anil, and Naveen Kumar M. "Management of Lifelong Learning: from Individuals to Learning Organizations and Societies." In Tenth Pan-Commonwealth Forum on Open Learning. Commonwealth of Learning, 2022. http://dx.doi.org/10.56059/pcf10.1990.

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Learning is the core competency required by the human beings, all living things, and even half-organisms like viruses, to survive in this world. Learning continues throughout one's life. When learning stops, it is almost the end of life. This fact remains explicit for anyone who observes life closely. Review of literature on progresses, innovations and overall successes of individuals, societies and organizations reveals that such achievements are greatly facilitated by the effective and efficient management of the lifelong learning process. Management of lifelong learning involves facilitatio
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Chacon, Joel Ramon, and Peter Dabrowski. "Production Technology Workbench: Developing and Scaling a Corporate Digital Product Using Agile Methods." In Abu Dhabi International Petroleum Exhibition & Conference. SPE, 2021. http://dx.doi.org/10.2118/207922-ms.

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Objectives/Scope The production technology working environment of an oil brownfield is usually an inconsistent collection of tools and spreadsheets. In this paper, we will explore Wintershall Dea's digitalisation journey from a patchwork of tools and spreadsheets to a unified corporate Production Technology Workbench (PTW) solution starting from the replacement of an existing and ageing tool on an asset on the Norwegian continental shelf and ending by incorporating the requirements of other assets from Wintershall Dea's diverse and geographically dispersed portfolio. Methods, Procedures, Proce
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Reports on the topic "Life change events Physiological effect"

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Delwiche, Michael, Boaz Zion, Robert BonDurant, Judith Rishpon, Ephraim Maltz, and Miriam Rosenberg. Biosensors for On-Line Measurement of Reproductive Hormones and Milk Proteins to Improve Dairy Herd Management. United States Department of Agriculture, February 2001. http://dx.doi.org/10.32747/2001.7573998.bard.

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The original objectives of this research project were to: (1) develop immunoassays, photometric sensors, and electrochemical sensors for real-time measurement of progesterone and estradiol in milk, (2) develop biosensors for measurement of caseins in milk, and (3) integrate and adapt these sensor technologies to create an automated electronic sensing system for operation in dairy parlors during milking. The overall direction of research was not changed, although the work was expanded to include other milk components such as urea and lactose. A second generation biosensor for on-line measuremen
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Yahav, Shlomo, John Brake, and Noam Meiri. Development of Strategic Pre-Natal Cycling Thermal Treatments to Improve Livability and Productivity of Heavy Broilers. United States Department of Agriculture, December 2013. http://dx.doi.org/10.32747/2013.7593395.bard.

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The necessity to improve broiler thermotolerance and live performance led to the following hypothesis: Appropriate comprehensive incubation treatments that include significant temperature management changes will promote angiogenesis and will improve acquisition of thermotolerance and carcass quality of heavy broilers through epigenetic adaptation. It was based on the following questions: 1. Can TM during embryogenesis of broilers induce a longer-lasting thermoregulatory memory (up to marketing age of 10 wk) that will improve acquisition of thermotolerance as well as increased breast meat yield
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Hochman, Ayala, Thomas Nash III, and Pamela Padgett. Physiological and Biochemical Characterization of the Effects of Oxidant Air Pollutants, Ozone and Gas-phase Nitric Acid, on Plants and Lichens for their Use as Early Warning Biomonitors of these Air Pollutants. United States Department of Agriculture, January 2011. http://dx.doi.org/10.32747/2011.7697115.bard.

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Introduction. Ozone and related oxidants are regarded as the most important phytotoxic air pollutant in many parts of the western world. A previously unrecognized component of smog, nitric acid, may have even greater deleterious effects on plants either by itself or by augmenting ozone injury. The effects of ozone on plants are well characterized with respect to structural and physiological changes, but very little is known about the biochemical changes in plants and lichens exposed to ozone and/or HNO3. Objectives.To compare and contrast the responses of crop plants and lichens to dry deposit
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Meiri, Noam, Michael D. Denbow, and Cynthia J. Denbow. Epigenetic Adaptation: The Regulatory Mechanisms of Hypothalamic Plasticity that Determine Stress-Response Set Point. United States Department of Agriculture, November 2013. http://dx.doi.org/10.32747/2013.7593396.bard.

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Our hypothesis was that postnatal stress exposure or sensory input alters brain activity, which induces acetylation and/or methylation on lysine residues of histone 3 and alters methylation levels in the promoter regions of stress-related genes, ultimately resulting in long-lasting changes in the stress-response set point. Therefore, the objectives of the proposal were: 1. To identify the levels of total histone 3 acetylation and different levels of methylation on lysine 9 and/or 14 during both heat and feed stress and challenge. 2. To evaluate the methylation and acetylation levels of histone
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Meidan, Rina, and Joy Pate. Roles of Endothelin 1 and Tumor Necrosis Factor-A in Determining Responsiveness of the Bovine Corpus Luteum to Prostaglandin F2a. United States Department of Agriculture, January 2004. http://dx.doi.org/10.32747/2004.7695854.bard.

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The corpus luteum (CL) is a transient endocrine gland that has a vital role in the regulation of the estrous cycle, fertility and the maintenance of pregnancy. In the absence of appropriate support, such as occurs during maternal recognition of pregnancy, the CL will regress. Prostaglandin F2a (PGF) was first suggested as the physiological luteolysin in ruminants several decades ago. Yet, the cellular mechanisms by which PGF causes luteal regression remain poorly defined. In recent years it became evident that the process of luteal regression requires a close cooperation between steroidogenic,
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