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Relevant bibliographies by topics / Life sciences. Influenza Immune response

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Academic literature on the topic 'Life sciences. Influenza Immune response'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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Journal articles on the topic "Life sciences. Influenza Immune response"

1

Miao, Hongyu, Joseph A. Hollenbaugh, Martin S. Zand, et al. "Quantifying the Early Immune Response and Adaptive Immune Response Kinetics in Mice Infected with Influenza A Virus." Journal of Virology 84, no. 13 (2010): 6687–98. http://dx.doi.org/10.1128/jvi.00266-10.

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ABSTRACT Seasonal and pandemic influenza A virus (IAV) continues to be a public health threat. However, we lack a detailed and quantitative understanding of the immune response kinetics to IAV infection and which biological parameters most strongly influence infection outcomes. To address these issues, we use modeling approaches combined with experimental data to quantitatively investigate the innate and adaptive immune responses to primary IAV infection. Mathematical models were developed to describe the dynamic interactions between target (epithelial) cells, influenza virus, cytotoxic T lymp

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Pertmer, Tamera M., Alp E. Oran, Janice M. Moser, Catherine A. Madorin, and Harriet L. Robinson. "DNA Vaccines for Influenza Virus: Differential Effects of Maternal Antibody on Immune Responses to Hemagglutinin and Nucleoprotein." Journal of Virology 74, no. 17 (2000): 7787–93. http://dx.doi.org/10.1128/jvi.74.17.7787-7793.2000.

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ABSTRACT Maternal antibody is the major form of protection from disease in early life when the neonatal immune system is still immature; however, the presence of maternal antibody also interferes with active immunization, placing infants at risk for severe bacterial and viral infection. We tested the ability of intramuscular and gene gun immunization with DNA expressing influenza virus hemagglutinin (HA) and nucleoprotein (NP) to raise protective humoral and cellular responses in the presence or absence of maternal antibody. Neonatal mice born to influenza virus-immune mothers raised full anti

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Fuess, Lauren E., Jorge H. Pinzón C, Ernesto Weil, Robert D. Grinshpon, and Laura D. Mydlarz. "Life or death: disease-tolerant coral species activate autophagy following immune challenge." Proceedings of the Royal Society B: Biological Sciences 284, no. 1856 (2017): 20170771. http://dx.doi.org/10.1098/rspb.2017.0771.

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Global climate change has increased the number and severity of stressors affecting species, yet not all species respond equally to these stressors. Organisms may employ cellular mechanisms such as apoptosis and autophagy in responding to stressful events. These two pathways are often mutually exclusive, dictating whether a cell adapts or dies. In order to examine differences in cellular response to stress, we compared the immune response of four coral species with a range of disease susceptibility. Using RNA-seq and novel pathway analysis, we were able to identify differences in response to im

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Holuka, Cyrielle, Myriam P. Merz, Sara B. Fernandes, et al. "The COVID-19 Pandemic: Does Our Early Life Environment, Life Trajectory and Socioeconomic Status Determine Disease Susceptibility and Severity?" International Journal of Molecular Sciences 21, no. 14 (2020): 5094. http://dx.doi.org/10.3390/ijms21145094.

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A poor socioeconomic environment and social adversity are fundamental determinants of human life span, well-being and health. Previous influenza pandemics showed that socioeconomic factors may determine both disease detection rates and overall outcomes, and preliminary data from the ongoing coronavirus disease (COVID-19) pandemic suggests that this is still true. Over the past years it has become clear that early-life adversity (ELA) plays a critical role biasing the immune system towards a pro-inflammatory and senescent phenotype many years later. Cytotoxic T-lymphocytes (CTL) appear to be pa

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Russell, Ryan F., Jacqueline U. McDonald, Laura Lambert, and John S. Tregoning. "Use of the Microparticle Nanoscale Silicon Dioxide as an Adjuvant To Boost Vaccine Immune Responses against Influenza Virus in Neonatal Mice." Journal of Virology 90, no. 9 (2016): 4735–44. http://dx.doi.org/10.1128/jvi.03159-15.

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ABSTRACTNeonates are at a high risk of infection, but vaccines are less effective in this age group; tailored adjuvants could potentially improve vaccine efficacy. Increased understanding about danger sensing by the innate immune system has led to the rational design of novel adjuvants. But differences in the neonatal innate immune response, for example, to Toll-like receptor (TLR) agonists, can reduce the efficacy of these adjuvants in early life. We therefore targeted alternative danger-sensing pathways, focusing on a range of compounds described as inflammasome agonists, including nanoscale

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Javanian, Mostafa, Arefeh Babazadeh, Soheil Ebrahimpour, Mehran Shokri, and Masomeh Bayani. "Clinical and laboratory findings of patients with the possible diagnosis of influenza hospitalized in affiliated hospitals of Babol University of Medical Sciences, 2015-2016." Current Issues in Pharmacy and Medical Sciences 31, no. 3 (2018): 113–16. http://dx.doi.org/10.1515/cipms-2018-0022.

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Abstract The clinical and para clinical manifestations of influenza in various patients have range from an autoimmune disease to a life-threatening respiratory infection. In addition, the severity of the disease is influenced by factors such as demographic factors, underlying diseases, and immune response. Therefore, in this study, we evaluated the clinical, laboratory and epidemiological characteristics of patients with this type of influenza in Babol (north of Iran). This study was conducted as a descriptive cross-sectional study from October 2015 to March 2016. Subsequently, in this study,

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Kim, Jong R., Beth C. Holbrook, Sarah L. Hayward, et al. "Inclusion of Flagellin during Vaccination against Influenza Enhances Recall Responses in Nonhuman Primate Neonates." Journal of Virology 89, no. 14 (2015): 7291–303. http://dx.doi.org/10.1128/jvi.00549-15.

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ABSTRACTInfluenza virus can cause life-threatening infections in neonates and young infants. Although vaccination is a major countermeasure against influenza, current vaccines are not approved for use in infants less than 6 months of age, in part due to the weak immune response following vaccination. Thus, there is a strong need to develop new vaccines with improved efficacy for this vulnerable population. To address this issue, we established a neonatal African green monkey (AGM) nonhuman primate model that could be used to identify effective influenza vaccine approaches for use in young infa

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Goodman, Alan G., Hui Zeng, Sean C. Proll, et al. "The Alpha/Beta Interferon Receptor Provides Protection against Influenza Virus Replication but Is Dispensable for Inflammatory Response Signaling." Journal of Virology 84, no. 4 (2009): 2027–37. http://dx.doi.org/10.1128/jvi.01595-09.

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ABSTRACT The innate immune response provides the first line of defense against foreign pathogens by responding to molecules that are a signature of a pathogenic infection. Certain RNA viruses, such as influenza virus, produce double-stranded RNA as an intermediate during the replication life cycle, which activates pathogen recognition receptors capable of inducing interferon production. By engaging interferon receptors, interferon activates the JAK-STAT pathway and results in the positive feedback of interferon production, amplifying the response to viral infection. To examine how deficiencies

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Chérasse, Sarah, and Serge Aron. "Impact of immune activation on stored sperm viability in ant queens." Proceedings of the Royal Society B: Biological Sciences 285, no. 1893 (2018): 20182248. http://dx.doi.org/10.1098/rspb.2018.2248.

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Ant queens mate on a single occasion early in life and store millions of sperm cells in their spermatheca. By carefully using stored sperm to fertilize eggs, they can produce large colonies of thousands of individuals. Queens can live for decades and their lifetime reproductive success is dependent on their ability to keep stored sperm alive. Maintaining high sperm viability requires metabolic energy which could trade-off with other costly processes such as immunity. We tested the impact of immune activation on the survival of stored sperm by prompting Lasius niger ant queens to mount a melani

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Liang, Bin, Lisa Hyland, and Sam Hou. "Nasal-Associated Lymphoid Tissue Is a Site of Long-Term Virus-Specific Antibody Production following Respiratory Virus Infection of Mice." Journal of Virology 75, no. 11 (2001): 5416–20. http://dx.doi.org/10.1128/jvi.75.11.5416-5420.2001.

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ABSTRACT Nasal immunoglobulin A provides an initial defense against inhaled respiratory pathogens. However, it is not known whether the nasal-associated lymphoid tissues (NALT) are able to mount an effective long-lasting pathogen-specific immune response, nor is it known whether functional differences exist between the organized NALT (O-NALT) and the diffuse NALT lining the nasal passages (D-NALT). Here we show that although both the O-NALT and the D-NALT are capable of producing virus-specific antibody in response to influenza virus infection, the frequency of specific antibody-forming cells

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Dissertations / Theses on the topic "Life sciences. Influenza Immune response"

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Ritz, Barry W. Gardner Elizabeth M. "Nutritional modulation of the innate immune response to influenza infection /." Philadelphia, Pa. : Drexel University, 2007. http://hdl.handle.net/1860/1787.

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Wu, Cheng Ying. "Characterization of innate immune response to «Nicotiana benthamiana»-derived Influenza H5 virus-like particles." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119400.

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Current influenza vaccine manufacturing processes using chicken-embryonated egg technology is a time-consuming and laborious process, and is currently the major drawback in counteracting pandemic influenza strain. One solution to that problem is the use of plants to generate vaccine antigen. Virus-like particles (VLP), produced from the tobacco plant Nicotiana benthamiana, represent a cost-effective, alternative platform for influenza vaccine production. Previous studies have shown that the immunization with VLP expressing the hemagglutinin (HA) protein from influenza virus H5N1 (H5-VLP) produ

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Maj, El sharif. "Early life stress and its association with epigenetics and immune system response." Thesis, Linköpings universitet, Biologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-138947.

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Stress can induce prolonged deleterious effects on many characteristics in chickens (Gallus gallus). Particular interest has been paid to early life stress. Social isolation as an early life stressor results in increased plasma corticosterone levels. Moreover, it induces behavioural and physiological changes as well as gene expression modifications in the hypothalamus. In the first part of my study, I aim to inquire into social isolation impacts on the short and long-term. Short and long-term effects were assessed by immune system, behaviour and weight. 82 male chickens were assigned to three

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Gailor, Russell. "The Relationship Between the Murine Primary Immune Response to Sheep Red Blood Cells & Heterosis." TopSCHOLAR®, 1989. https://digitalcommons.wku.edu/theses/2373.

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Two inbred strains of mice, BALB/c and C57BL, were crossbred to produce Fl hybrids. This breeding scheme ensured a high degree of genetic heterozygosity as exemplified by the fact that the average weight of the Fl hybrids at 10 weeks of age was 10.1 percent greater that that of their contemporaries in the inbred parental strains. The three lines of mice were then challenged with a 0.5 ml intraperitoneal injection of two-percent sheep red blood cells (SRBC). After a 15-day period the mice were bled and their sera were microtitrated for anti-SRBC agglutinin and the titers statistically analyzed.

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Hunzeker, John T. "Differential effects of stress on the immune response to influenza A/PR8 virus infection in mice." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1080588837.

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Thesis (Ph. D.)--Ohio State University, 2004.<br>Title from first page of PDF file. Document formatted into pages; contains xvi, 231 p.; also includes graphics Includes bibliographical references (p. 211-231). Available online via OhioLINK's ETD Center

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Palmer, Duncan. "Selection along the HIV-1 genome through the CTL mediated immune response." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:1cd57b15-485d-4f5a-8a1c-7702a355c597.

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During human immunodeficiency virus 1 (HIV-1) infection, the viral population is in constant battle with the host immune system. The cytotoxic T-lymphocyte (CTL) response, a branch of the adaptive immune response, is implicated in viral control and can drive viral evolution in the infected host population. Endogenous viral peptides, or ‘epitopes’, are presented to CTLs by human leukocyte antigen (HLA) class I molecules on the surface of infected cells where they may be identified as non-self. Mutations in or proximal to a viral epitope can result in ‘escape’ from CTLs targeting that epitope. T

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Tomkinson, Blake E. "The Cellular Immune Response to Epstein-Barr Virus during Active Infectious Mononucleosis: a Thesis." eScholarship@UMMS, 1988. http://escholarship.umassmed.edu/gsbs_diss/292.

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Epstein-Barr virus (EBV) induced infectious mononucleosis (IM) is characterized by the activation and expansion of T lymphocytes and the induction of cytotoxic responses able to mediate the lysis of EBV-uninfected, allogeneic MHC mismatched and EBV-infected autologous target cells. Freshly isolated peripheral blood mononuclear cells (PBMC) were used to examine the nature of these cellular immune responses. Activated lymphocytes, as identified by HLA-DR expression, associated with EBV induced IM were shown to be a heterogeneous population containing significantly elevated cytotoxic/suppress

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Boyle, Christine Margaret. "DNA Immunization: Basic Mechanisms of the DNA-Raised Antibody Response Using an Influenza Hemagglutinin-Expressing Plasmid: A Dissertation." eScholarship@UMMS, 2000. https://escholarship.umassmed.edu/gsbs_diss/151.

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In DNA immunization a plasmid expressing an antigen of interest is inoculated into an animal and antigen-specific humoral and cellular immune responses are raised. In this dissertation we sought to further our understanding of antibody responses raised following DNA inoculation. Specifically, we examined the role of lymphoid tissue in the initiation and maintenance of the long-term antibody response, the role of CD4+ and CD8+ T cells in the DNA-raised antibody response, the longevity of functional antigen expression, and the nature of the antigen presenting cell. In all of these studies mice w

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Boyle, Christine Margaret. "DNA Immunization: Basic Mechanisms of the DNA-Raised Antibody Response Using an Influenza Hemagglutinin-Expressing Plasmid: A Dissertation." eScholarship@UMMS, 2003. http://escholarship.umassmed.edu/gsbs_diss/151.

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In DNA immunization a plasmid expressing an antigen of interest is inoculated into an animal and antigen-specific humoral and cellular immune responses are raised. In this dissertation we sought to further our understanding of antibody responses raised following DNA inoculation. Specifically, we examined the role of lymphoid tissue in the initiation and maintenance of the long-term antibody response, the role of CD4+ and CD8+ T cells in the DNA-raised antibody response, the longevity of functional antigen expression, and the nature of the antigen presenting cell. In all of these studies mice w

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Acquah, Phyllis V. "Inhibition of Margination and Diapedesis of Neutrophils by Protein Synthesis Blockade." VCU Scholars Compass, 2006. http://scholarscompass.vcu.edu/etd/1439.

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Acute Respiratory Distress Syndrome (ARDS), an age-old clinical problem facing the Emergency Department and Intensive Care Units of all health systems, is a common debilitating lung condition consequent upon severe systemic inflammation. Although several studies have gone into understanding the epidemiology and pathogenesis of the disease thus making way for new advances in treatment strategies, there seems to be no known study tailored to its prevention. Neutrophil extravasation within the tissues during inflammation is the hallmark of this syndrome. Our study sought to block excessive neutro

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Books on the topic "Life sciences. Influenza Immune response"

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M, Locksley Richard, and Robertson Miranda, eds. Immunity: The immune response in infectious and inflammatory disease. New Science Press in association with Oxford University Press, 2007.

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DeFranco, Anthony, Richard Locksley, and Miranda Robertson. Immunity: The Immune Response to Infectious and Inflammatory Disease (Primers in Biology). Oxford University Press, USA, 2007.

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R, Bock Gregory, Goode Jamie, and Novartis Foundation, eds. Generation and effector functions of regulatory lymphocytes. John Wiley, 2003.

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Foundation, Novartis. Generation and Effector Functions of Regulatory Lymphocytes (Novartis Foundation Symposia). Wiley, 2003.

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Jankovic, Branislav D., and Nicola Fabris. Ontogenetic and Phylogenetic Mechanisms of Neuroimmunomodulation: From Molecular Biology to Psychosocial Sciences (Annals of the New York Academy of Sciences). New York Academy of Sciences, 1992.

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Fabris, N., B. D. Jankovic, and N. H. Spector. Ontogenetic and Phylogenetic Mechanisms of Neuroimmunomodulation: From Molecular Biology to Psychosocial Sciences (Annals of New York Academy of Sciences) Volume 650. New York Academy of Sciences, 1992.

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N, Fabris, ed. Ontogenetic and phylogenetic mechanisms of neuroimmunomodulation: From molecular biology to psychosocial sciences. New York Academy of Sciences, 1992.

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Jeanette, Thorbecke G., and Tsiagbe Vincent Kwaku, eds. The biology of germinal centers in lymphoid tissue. Springer, 1998.

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Thorbecke, G. Jeanette, and V. K. Tsaigbe. The Biology of Germinal Centers in Lymphoid Tissue: Biotechnology Intelligence Unit (Ecological Studies / Analysis and Synthesis,). Springer-Verlag Telos, 1998.

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Janeway, Charles A. Jr, Jules A. Hoffmann, and Shunji Natori. Phylogenetic Perspectives in Immunity: The Insect Host Defense (Molecular Biology Intelligence Unit). R. G. Landes, 1994.

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Book chapters on the topic "Life sciences. Influenza Immune response"

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Marion, James. "Immunology and the Immune Response." In Molecular Life Sciences. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4614-1531-2_648.

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Marion, James. "Immunology and the Immune Response." In Molecular Life Sciences. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-6436-5_648-1.

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Robert, J. "Humoral Immune Response of Amphibians." In Reference Module in Life Sciences. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809633-8.12185-5.

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Yáñez, Alberto, Celia Murciano, M. Luisa Gil, and Daniel Gozalbo. "Immune Response to Candida albicans Infection." In Reference Module in Life Sciences. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-809633-8.12075-8.

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V. Yemelyanov, Vladislav, Roman K. Puzanskiy, Mikhail S. Burlakovskiy, Lyudmila A. Lutova, and Maria F. Shishova. "Metabolic Profiling of Transgenic Tobacco Plants Synthesizing Bovine Interferon-Gamma." In Metabolomics - Methodology and Applications in Medical Sciences and Life Sciences. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96862.

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Interferon-gamma belongs to a large family of cytokines – multifunctional secreted proteins involved in animal non-specific immune response. Previously inbred lines of Nicotiana tabacum L. plants harboring a heterologous gene of bovine interferon-gamma Bt-sIFNG under the control of a constitutive 35S CaMV promoter have been created by Agrobacterium-mediated genetic transformation. The antiviral and immunomodulatory activities of plant-produced interferon-gamma in bovine cell culture and laboratory animals (mice) were observed. A state-of-the-art GS-MS technique has been used to identify the possible effect of the transformation on the plant’s metabolome. Total profiles included 350 metabolites from leaves, among which 150 substances were identified up to their class and 80 up to the exact metabolite. Metabolite profiling revealed that plants able to synthesize interferon-gamma are characterized by a higher level of amino acids and other substances involved in nitrogen metabolism. In transgenic plants intensification of the secondary metabolism was also detected. Some alterations were distinguished in plant metabolome depending on cultivation conditions.

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"Infection and immunity." In Oxford Handbook of Medical Sciences, edited by Robert Wilkins, Ian Megson, and David Meredith. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198789895.003.0012.

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‘Infection and immunity’ considers the response of the body to pathogens, such as bacteria, viruses, prions, fungi, and parasites, which are discussed in terms of their nature, life cycle, and modes of infection. The role of the immune system in defence against infection is discussed, including innate and adaptive (acquired) immunity, antigens, the major histocompatibility complex, and the different cell types involved (antigen-presenting cells, T-cells, and B-cells). The mechanisms and cellular basis of inflammation are considered, as are post-infection repair mechanisms, and pathologies of the immune system such as hypersensitivity, autoimmunity and transplantations, and immunodeficiency (both primary and secondary to other diseases).

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