Relevant bibliographies by topics / Ligamentum Flavum (LF)

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Academic literature on the topic 'Ligamentum Flavum (LF)'

Author: Grafiati
Published: 5 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "Ligamentum Flavum (LF)"

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Yabe, Yutaka, Keisuke Ishikawa, Daisuke Kurosawa, Eiichi Murakami, and Toshimi Aizawa. "Buckling of the Ligamentum Flavum in Patients with Lumbar Spinal Canal Stenosis." Spine 49, no. 17 (2024): E284—E290. http://dx.doi.org/10.1097/brs.0000000000004941.

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Study Design. Experimental study. Objective. We sought to elucidate the association between ligamentum flavum thickening and tissue buckling, and the clinical and imaging factors related to buckling by comparing the ligamentum flavum thickness on MRI images and within the actual tissue. Summary of Background Data. Ligamentum flavum thickening is a main contributor to lumbar spinal canal stenosis. Buckling of the tissue may contribute to ligamentum flavum thickening along with tissue hypertrophy; however, this association has not been established conclusively. Materials and Methods. Ligamentum
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Pradeep, Kumar, Pathak Alpana, Kumar Srivastava Rupesh, Suman Sanjeev, and S. Prasad V. "Retrospective Comparative Evaluation of Thickness of Ligamentum Flavum in Normal and Stenosis of Lumbar Vertebrae." International Journal of Current Pharmaceutical Review and Research 16, no. 03 (2024): 512–15. https://doi.org/10.5281/zenodo.12792470.

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AbstractBackground: Ligamentum Flavum (LF) wraps around the medial aspect spinal articulation and is composed moreelastic than collagen fibres, hence it's yellow in colour. Its elasticity diminishes with age and there is loss of elasticfibres and a concomitant increase of collagen fibres. The study compared the thickness of the LF betweenindividuals with normal spinal conditions and those with lumbar spinal stenosis (LSS). The goal was to investigatevariations in LF thickness and asymmetry observed in CT images, taking into account the size of the associatedvertebral bodies across different ag
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Suh, Jeong Hun. "The Role of the Ligamentum Flavum Area as a Morphological Parameter of Lumbar Central Spinal Stenosis." Pain Physician 3, no. 20;3 (2017): E419—E424. http://dx.doi.org/10.36076/ppj.2017.e424.

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Background: Hypertrophy of the ligamentum flavum (LF) has been considered as a major cause of lumbar central spinal stenosis (LCSS). Previous studies have found that ligamentum flavum thickness (LFT) is correlated with aging, disc degeneration, and lumbar spinal stenosis. However, hypertrophy is different from thickness. Thus, to evaluate hypertrophy of the whole LF, we devised a new morphological parameter, called the ligamentum flavum area (LFA). Objectives: We hypothesized that the LFA is a key morphologic parameter in the diagnosis of LCSS. Study Design: Retrospective observational study.
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4

Hur, Junseok W., Bum-Joon Kim, Jin-Hyun Park, et al. "The Mechanism of Ligamentum Flavum Hypertrophy." Neurosurgery 77, no. 2 (2015): 274–82. http://dx.doi.org/10.1227/neu.0000000000000755.

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Abstract BACKGROUND: Biochemical alterations associated with mechanical stress have been explored as an initiating step in the pathological progression of ligamentum flavum hypertrophy (LFH); however, this mechanism remains poorly understood. Recently, the inflammation induced after mechanical stress and the subsequent response of ligamentum flavum (LF) cells have been implicated in LFH pathology. OBJECTIVE: To investigate the hypothesis that angiogenesis may be a critical link between hypertrophy and a series of stimulating events, including mechanical stress. METHODS: LF from 20 lumbar spina
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5

Appolonio, Paulo Roberto, Thiago Mattar, Alexandre Barros Costa, Edgar Santiago Valesin Filho, and Luciano Miller Reis Rodrigues. "Thickening of spine ligamentum flavum and facet tropism." Coluna/Columna 13, no. 1 (2014): 39–42. http://dx.doi.org/10.1590/s1808-18512014130100350.

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OBJECTIVE: This study investigated the thickening of the ligamentum flavum (LF) and its correlation with facet tropism and its severity at different levels of the spine. METHOD: This retrospective study was performed with patients with chronic back pain consecutively admitted to a specialized spinal surgery service between January 2012 and January 2013. All patients underwent magnetic resonance imaging (MRI) to measure the thickness of the LF and facet tropism severity (severe, moderate or absent) according to the spine levels (L3 -L4, L4-L5, L5-S1). The association between the thickness of LF
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6

Ito, Kei, Hideki Kise, Satoshi Suzuki, et al. "Potential Involvement of Oxidative Stress in Ligamentum Flavum Hypertrophy." Journal of Clinical Medicine 12, no. 3 (2023): 808. http://dx.doi.org/10.3390/jcm12030808.

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Oxidative stress (OS) results in many disorders, of which degenerative musculoskeletal conditions are no exception. However, the interaction between OS and ligamentum flavum (LF) hypertrophy in lumbar spinal canal stenosis is not clearly understood. The first research question was whether OS was involved in LF hypertrophy, and the second was whether the antioxidant N-acetylcysteine (NAC) was effective on LF hypertrophy. In total, 47 LF samples were collected from patients with lumbar spinal disorders. The cross-sectional area of LF was measured on axial magnetic resonance imaging. Immunohistoc
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7

Li, Shen MD Jing Niu MD Yaozong Di MD and Jike Lu* MD PhD. "Thoracic Spinal Stenosis from Calcified Ligamentum Flavum Co-Existing with L5-S1 Foraminal Stenosis - A Case Report and Literature Review." Mega Journal of Case Reports 8, no. 3 (2025): 2001–10. https://doi.org/10.5281/zenodo.15017060.

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<strong>Abstract</strong> Calcification of the ligamentum flavum (LF) is a rare cause of spinal stenosis. The process can occur at any level in the spine, often presents with local pain or radicular symptoms, and is a distinct process from ossification of the spinal ligaments in pathogenesis and treatment approach. Few case reports have described multiple level involvements in the thoracic spine that results in sensorimotor deficits and myelopathy. We reported a 50-year-old male who presented with progressive sensorimotor deficits from T10 distally that resulted in complete sensory deficits an
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8

KC, Sudeep, Abhushan Siddhi Tuladhar, Riwaz Acharya, and Subodh Shrestha. "Evaluation of the Thickness of Ligamentum Flavum at the Level of Lumbosacral Spine (L4-L5, L5-S1) and its Relationship with Degenerative Disc Changes in Patients Undergoing MRI of Lumbosacral Spine." Nepalese Journal of Radiology 14, no. 1 (2024): 22–28. http://dx.doi.org/10.3126/njr.v14i1.64626.

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Introduction: Low back pain (LBP) is a very common cause of disability in working-age adults; with degenerative changes being the predominant cause apart from anatomical factors. Degenerative changes in the lumbar spine are associated with the alteration of the thickness of the Ligamentum Flavum (LF), which predisposes to clinical symptoms. Methods: This was a prospective study conducted among ninety symptomatic (LBP) patients who underwent magnetic resonance imaging (MRI) and the images were evaluated to measure the thickness of the LF and evaluate the degree of disc degeneration by the Pfirr
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9

Chelladurai, Amarnath, Suhasini Balasubramaniam, Sarenya Preyah Anbazhagan, Sathyan Gnanasihamani, and Sukumar Ramaswami. "Dorsal Spinal Ligamentum Flavum Thickening: A Magnetic Resonance Imaging Study." Asian Spine Journal 12, no. 1 (2018): 47–51. http://dx.doi.org/10.4184/asj.2018.12.1.47.

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&lt;sec&gt;&lt;title&gt;Study Design&lt;/title&gt;&lt;p&gt;A retrospective radiological study of the ligamentum flavum (LF).&lt;/p&gt;&lt;/sec&gt;&lt;sec&gt;&lt;title&gt;Purpose&lt;/title&gt;&lt;p&gt;We determined the relationship of dorsal spinal LF thickening with age and sex using magnetic resonance imaging (MRI). We also determined whether LF thickening has a predominant tendency to occur at a specific dorsal level and on a specific side.&lt;/p&gt;&lt;/sec&gt;&lt;sec&gt;&lt;title&gt;Overview of Literature&lt;/title&gt;&lt;p&gt;Many researchers have studied LF thickness at dorsal levels in
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10

Zhou, Tangjun, Lin Du, Chen Chen, et al. "Lysophosphatidic Acid Induces Ligamentum Flavum Hypertrophy Through the LPAR1/Akt Pathway." Cellular Physiology and Biochemistry 45, no. 4 (2018): 1472–86. http://dx.doi.org/10.1159/000487574.

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Background/Aims: Hypertrophic ligamentum flavum (LF) is a major cause of lumbar spinal stenosis. Our previous work showed that high levels of lysophosphatidic acid (LPA) expression are positively correlated with LF hypertrophy. This study aimed to further unveil how LPA regulates LF hypertrophy Methods: We studied LPAR1 expression in human LF cells using PCR and western blotting. Cell viability cell cycle, apoptosis rate and molecular mechanisms were assayed in LPAR1 knockdown or overexpression LF cells. LF hypertrophy and the molecular mechanism was confirmed in human samples and in in vivo s
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Conference papers on the topic "Ligamentum Flavum (LF)"

1

Vaughan, Neil, and Venketesh N. Dubey. "Interpreting Ultrasound Images for Accurate Epidural Needle Insertion." In 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3494.

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This work presents development and testing of image processing algorithms for the automatic detection of landmarks within ultrasound images. The aim was to automate ultrasound analysis, for use during the process of epidural needle insertion. For epidural insertion, ultrasound is increasingly used to guide the needle into the epidural space. Ultrasound can improve the safety of epidural and was recommended by the 2008 NICE guidelines (National Institute for Health and Care Excellence). Without using ultrasound, there is no way for the anaesthetist to observe the location of the needle within t
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