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Relevant bibliographies by topics / Ligands

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Academic literature on the topic 'Ligands'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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Journal articles on the topic "Ligands"

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Oszwałdowski, Sławomir, Katarzyna Zawistowska-Gibuła, and Kenneth Roberts. "Characterization of CdSe quantum dots with bidentate ligands by capillary electrophoresis." Open Chemistry 9, no. 4 (2011): 572–84. http://dx.doi.org/10.2478/s11532-011-0037-3.

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AbstractThe CdSe quantum dots (QDs) with bidentate ligands: a-diimine (NN) and dihydrolipoic acid (DHLA) were synthesized and characterized by UV-Vis, particle size and capillary electrophoretic techniques. Two systems were analyzed: CdSe with one ligand (CdSe/ligand) and CdSe with two different ligands (CdSe//ligand1/ligand2), where ligand = α-diimine or DHLA. Hydrodynamic features of functionalized QDs were characterized by zone capillary electrophoretic (CZE), and particle size techniques and these methods were consistent. It was established that CZE, micellar (MEKC) and microemulsion (MEEK

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Bakhtiari, Atefeh, and Javad Safaei-Ghomi. "Effects of Chiral Ligands on the Asymmetric Carbonyl-Ene Reaction." Synlett 30, no. 15 (2019): 1738–64. http://dx.doi.org/10.1055/s-0037-1611875.

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The carbonyl-ene reaction is one of the most well-known reactions for C–C bond formation. Based on frontier molecular orbitals (FMO), carbonyl-ene reactions occur between the highest occupied molecular orbital (HOMO) of the ene compound bearing an active hydrogen atom at the allylic center and the lowest unoccupied molecular orbital (LUMO) of the electron-deficient enophile, which is a carbonyl compound. A high activation barrier enforces the concerted ene reaction rather than a Diels–Alder reaction at high temperature. Employing a catalytic system can eliminate defects in the ene reaction, an

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Murphy, Patrick B., Feng Liu, Stephen C. Cook, et al. "Structural control of Au and Au–Pd nanoparticles by selecting capping ligands with varied electronic and steric effects." Canadian Journal of Chemistry 87, no. 11 (2009): 1641–49. http://dx.doi.org/10.1139/v09-127.

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Weakly interacting ligands including three Gemini surfactants, didodecyldimethylammonium bromide (DDAB), and amines (RNH2, R2NH, and R3N) were used to prepare Au nanoparticles (NPs). Aqueous Au NPs capped with DDAB and Gemini surfactants showed similar sizes (3–4 nm), whereas toluene-based NPs stabilized with DDAB, amines, and their mixtures range from 2.5 to 9.3 nm. Ligand effect on Au–Pd NP structure was also studied with EXAFS. These findings were consistently accounted for by considering the ligand’s electronic/steric effects and mixed ligands coadsorption, and suggest useful ways to contr

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Guseva, Polina B., Alexander R. Badikov, Oleg S. Butorlin, et al. "Complexation of Lanthanides(III) Ions with Terephthalic Acid in Aqueous Solutions by Potentiometric Titration Combined with Photoluminescence Spectroscopy." Chemistry 7, no. 2 (2025): 57. https://doi.org/10.3390/chemistry7020057.

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The complexation behavior of lanthanide(III) ions with terephthalic acid (1,4-benzene-dicarboxylic acid) in 0.01 M KNO3 aqueous solutions was studied across a broad pH range and at two metal-to-ligand ratios using potentiometric titration combined with photoluminescence spectroscopy. Chemometric analysis of titration curves enabled the determination of relative molar fractions, stability constants, and probable stoichiometry of the formed complexes. In solutions with a 1:2 metal-to-ligand ratio, bis-complexes (two terephthalate ligands per lanthanide ion) predominated, while ligand-rich condit

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Finkina, Ekaterina I., Daria N. Melnikova, Ivan V. Bogdanov, et al. "Impact of Different Lipid Ligands on the Stability and IgE-Binding Capacity of the Lentil Allergen Len c 3." Biomolecules 10, no. 12 (2020): 1668. http://dx.doi.org/10.3390/biom10121668.

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Previously, we isolated the lentil allergen Len c 3, belonging to the class of lipid transfer proteins, cross-reacting with the major peach allergen Pru p 3 and binding lipid ligands. In this work, the allergenic capacity of Len c 3 and effects of different lipid ligands on the protein stability and IgE-binding capacity were investigated. Impacts of pH and heat treating on ligand binding with Len c 3 were also studied. It was shown that the recombinant Len c 3 (rLen c 3) IgE-binding capacity is sensitive to heating and simulating of gastroduodenal digestion. While being heated or digested, the

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Moreno, Maria João, Luís M. S. Loura, Jorge Martins, Armindo Salvador, and Adrian Velazquez-Campoy. "Analysis of the Equilibrium Distribution of Ligands in Heterogeneous Media–Approaches and Pitfalls." International Journal of Molecular Sciences 23, no. 17 (2022): 9757. http://dx.doi.org/10.3390/ijms23179757.

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The equilibrium distribution of small molecules (ligands) between binding agents in heterogeneous media is an important property that determines their activity. Heterogeneous systems containing proteins and lipid membranes are particularly relevant due to their prevalence in biological systems, and their importance to ligand distribution, which, in turn, is crucial to ligand’s availability and biological activity. In this work, we review several approaches and formalisms for the analysis of the equilibrium distribution of ligands in the presence of proteins, lipid membranes, or both. Special a

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Mura, Ulrike, Matthias Pfeiffer, Rupert Handgretinger, and Peter J. Lang. "Expression of Activating Natural Killer Cell Receptor Ligands in Childhood Acute Lymphoblastic Leukemia." Blood 108, no. 11 (2006): 4478. http://dx.doi.org/10.1182/blood.v108.11.4478.4478.

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Abstract Activating and inhibitory cell surface receptors regulate natural killer (NK) cell effector functions. The extent of expression of their activating ligands on target cells probably plays a critical role in tumor immune surveillance, but the data of this expression on blasts of leukemia patients are still poor. We examined blasts of children with ALL for the activating human NKG2D ligands MICA, MICB, ULBP1, ULBP2 and ULBP3, and for the ligands of the activating human natural cytotoxic receptors (NCRs) NKp30, NKp44 and NKp46. Using ligand specific mouse monoclonal antibodies and flow cy

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Fan, Qikui, Hao Yang, Juan Ge, et al. "Customizable Ligand Exchange for Tailored Surface Property of Noble Metal Nanocrystals." Research 2020 (January 21, 2020): 1–12. http://dx.doi.org/10.34133/2020/2131806.

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It is highly desirable, while still challenging, to obtain noble metal nanocrystals with custom capping ligands, because their colloidal synthesis relies on specific capping ligands for the shape control while conventional ligand exchange processes suffer from “the strong replaces the weak” limitation, which greatly hinders their applications. Herein, we report a general and effective ligand exchange approach that can replace the native capping ligands of noble metal nanocrystals with virtually any type of ligands, producing flexibly tailored surface properties. The key is to use diethylamine

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Miller, Shannon M., Van Cybulski, Lois Walsh, et al. "Investigation of novel TLR7/8 ligands in combination with TLR4 ligands as adjuvants to drive cell mediated anti-influenza immunity." Journal of Immunology 200, no. 1_Supplement (2018): 125.16. http://dx.doi.org/10.4049/jimmunol.200.supp.125.16.

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Abstract Influenza is a highly communicative viral pathogen that infects 9–35 million individuals and results in 12,000–56,000 deaths in the US annually. For the most commonly used seasonal influenza vaccine, historical efficacy rates range from 10–60% thus improvements to the current vaccine are needed. We identified a novel series of synthetic TLR7/8 ligands that improve influenza vaccine efficacy when used alone or in combination with our synthetic TLR4 ligand. In human PBMCs, TLR7/8 ligands elicited secretion of the inflammatory cytokines TNFα, IL-6, and IL-1β as well as the Th1-polarizing

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Sim, Jaeung, Taemin Kim та Jin Kuk Yang. "Poly[(μ6-benzene-1,3,5-tricarboxylato-κ6O1:O1′:O3:O3′:O5:O5′)tris(N,N-dimethylformamide-κO)tris(μ3-formato-κ3O:O:O′)trizinc(II)]". Acta Crystallographica Section E Structure Reports Online 69, № 11 (2013): m619. http://dx.doi.org/10.1107/s1600536813028687.

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The asymmetric unit of the title compound, [Zn3(HCO2)3(C9H3O6)(C3H7NO)3]n, contains one Zn ion, one formate ligand, oneN,N-dimethylformamide (DMF) ligand and one-third of a benzene-1,3,5-tricarboxylate (btc) ligand situated on a crystallographic 3 axis. Each ZnIIatom is coordinated by one O atom from a DMF ligand, two O atoms from two btc ligands and three O atoms from three formate ligands in a distorted octahedral geometry. The ZnIIatoms are connected by the formate and btc ligands, forming hexanuclear cores, which are linked by btc ligands, constructing a two-dimensional layered network alo

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Dissertations / Theses on the topic "Ligands"

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Stewart, Peter John. "Metal-ligand multiply bonded complexes supported by amidinate ligands." Thesis, University of Nottingham, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243747.

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Maaß, Christian. "Exploring Metal-Ligand Interactions of Pyrrole Based Pincer Ligands." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://hdl.handle.net/11858/00-1735-0000-0022-5E31-1.

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Baylies, Christian John. "Synthesis of multidentate pyridyl-thiazole ligands and ligand recognition studies." Thesis, University of Huddersfield, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399824.

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Yamamoto, Izumi. "Structure-function studies of GABA-C receptor ligands." Thesis, The University of Sydney, 2012. https://hdl.handle.net/2123/28927.

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Throughout the central nervous system (CNS), the Cys-loop superfamily of ligand-gated ion channels {LGICs), including nicotinic acetylcholine, serotonin type-3A, strychnine-sensitive glycine and y-aminobutyric acid A/C receptors, play important roles in synaptic transmission by converting chemical signals into electric signals. Designing potent and subtype-selective ligands with therapeutic value requires knowledge about how ligands interact with their binding sites. y-Aminobutyric acid (GABA) is the predominant inhibitory neurotransmitter in the mammalian CNS and its binding modes at GABA r

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Badarau, Eduard Guillaumet Gérald Fînaru Adriana. "Conception, synthèse et évaluation biologique de nouvelles classes de ligands sérotoninergiques 5-HT7." S. l. : S. l. : Orléans ; Université de Bacau, 2009. http://intranet.univ-orleans.fr/bibliotheques/theses/eduard.badarau_1653.pdf.

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Thèse de doctorat : Chimie et physicochimie des composés d'intérêt biologique : Orléans : 2009. Thèse de doctorat : Chimie et physicochimie des composés d'intérêt biologique : Université de Bacau : 2009.<br>Titre provenant de l'écran-titre.

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Duraj-Thatte, Anna. "Fluorescent GFP chromophores as potential ligands for various nuclear receptors." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/44764.

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Nuclear receptors are ligand activated transcription factors, where upon binding with small molecule ligands, these proteins are involved in the regulation of gene expression. To date there are approximately 48 human nuclear receptors known, involved in multiple biological and cellular processes, ranging from differentiation to maintenance of homeostasis. Due to their critical role in transcriptional regulation, these receptors are implicated in several diseases. Currently, 13% of prescribed drugs in the market are NR ligands for diseases such as cancer, diabetes and osteoporosis. In addition

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Kandala, Srikanth. "Diphosphine Ligand Substitution in H4Ru4(CO)12: X-ray Diffraction Structures and Reactivity Studies of the Diphosphine Substituted Cluster Products." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5410/.

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The tetraruthenium cluster H4Ru4(CO)12 has been studied for its reactivity with the unsaturated diphosphine ligands (Z)-Ph2PCH=CHPPh2, 4,5-bis (diphenylphosphino)-4-cyclopenten-1,3-dione, bis(diphenyphosphino)benzene and 1,8- bis(diphenyl phosphino)naphthalene under thermal, near-UV photolysis, and Me3NO-assisted activation. All three cluster activation methods promote loss of CO and furnish the anticipated substitution products that possess a chelating diphosphine ligand. Clusters 1, 2, 3 and 4 have been characterized in solution by IR and NMR spectroscopies, and these data are discussed with

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Malgas, Rehana. "The application of novel multinuclear catalysts derived from dendrimeric ligands in the polymerization and oligomerization of unsaturated hydrocarbons." Thesis, University of the Western Cape, 2007. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_7858_1183727432.

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<p>G1 and G2 dendrimeric salicylaldimine ligands containing both substituted and unsubstituted aryl rings were synthesized via a Schiff base condensation of the appropriate salicylaldehyde and the peripheral amino groups of the corresponding G1 and G2 polypropyleneimine dendrimers. The new ligands were characterized using FTIR, 1H NMR and 13C NMR spectroscopy, elemental analysis and ESI mass spectrometry. The dendrimeric ligands were converted to multinuclear nickel complexes by reaction with nickelacetate. The metal complexes were characterized by FTIR spectroscopy, elemental analysis and ESI

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Lewis, William. "Chiral Heterocyclic Ligands." Thesis, University of Canterbury. Chemistry, 2007. http://hdl.handle.net/10092/1383.

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This thesis describes the preparation and characterisation of a number of homochiral coordination and metallosupramolecular assemblies. These species were formed from the reaction of chiral pyridine and quinoline containing ligands and metal ions. The combination of traditional coordination chemistry and supramolecular interactions led to a range of polymeric and network structures being formed. The ligands used in this thesis can be divided into two broad categories: alkaloids and ligands derived from them, and amino acid-based ligands. In the first category three new ligands were synthesi

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Seymour, L. C. "Chiral organometallic ligands." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279979.

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Books on the topic "Ligands"

1

S, Braterman Paul, ed. Reactions of coordinated ligands. Plenum Press, 1986.

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Cancro, Michael P., ed. BLyS Ligands and Receptors. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60327-013-7.

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Braterman, Paul S., ed. Reactions of Coordinated Ligands. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-0755-6.

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Braterman, Paul S., ed. Reactions of Coordinated Ligands. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1785-2.

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1941-, Navratil James D., and Walton Harold F. 1912-, eds. Ligand exchange chromatography. CRC Press, 1988.

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Zhou, Qi-Lin. Privileged chiral ligands and catalysts. Wiley-VCH, 2011.

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Zhou, Qi-Lin, ed. Privileged Chiral Ligands and Catalysts. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527635207.

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Ahmed, Rafi, and Tasuku Honjo, eds. Negative Co-Receptors and Ligands. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-19545-7.

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Rammensee, Hans-Georg, Jutta Bachmann, and Stefan Stevanović. MHC Ligands and Peptide Motifs. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-662-22162-4.

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Berend, Olivier, Wijngaarden I. van, and Soudijn W, eds. Serotonin receptors and their ligands. Elsevier, 1997.

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Book chapters on the topic "Ligands"

1

Fischer, Gabriele, Annemarie Unger, W. Wolfgang Fleischhacker, et al. "Ligands." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_1182.

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Cremer, Julian, Tuan Le, Djork-Arné Clevert, and Kristof T. Schütt. "Latent-Conditioned Equivariant Diffusion for Structure-Based De Novo Ligand Generation." In Lecture Notes in Computer Science. Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-72381-0_4.

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AbstractWe propose PoLiGenX for de novo ligand design using latent-conditioned, target-aware equivariant diffusion. Our model leverages the conditioning of the generation process on reference molecules within a protein pocket to produce shape-similar de novo ligands that can be used for target-aware hit expansion and hit optimization. The results of our study showcase the efficacy of PoLiGenX in ligand design. Docking scores indicate that the generated ligands exhibit superior binding affinity compared to the reference molecule while preserving the shape. At the same time, our model maintains

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Lefort, Laurent, and Johannes G. de Vries. "Phosphoramidite Ligands." In Phosphorus(III) Ligands in Homogeneous Catalysis: Design and Synthesis. John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781118299715.ch4.

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Müller, Christian. "Phosphinine Ligands." In Phosphorus(III) Ligands in Homogeneous Catalysis: Design and Synthesis. John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781118299715.ch8.

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Schirripa, Marta, Heinz-Josef Lenz, and Stefan J. Scherer. "VEGF Ligands." In Cancer Therapeutic Targets. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4419-0717-2_17.

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Kawaguchi, Shinichi. "Monoatomic Ligands." In Inorganic Chemistry Concepts. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-50148-7_2.

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Kawaguchi, Shinichi. "Diatomic Ligands." In Inorganic Chemistry Concepts. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-50148-7_3.

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Kawaguchi, Shinichi. "Triatomic Ligands." In Inorganic Chemistry Concepts. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-50148-7_4.

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Bausch, Cory C., and Andreas Pfaltz. "PHOX Ligands." In Privileged Chiral Ligands and Catalysts. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527635207.ch6.

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Pellissier, Hélène. "TADDOLate Ligands." In Privileged Chiral Ligands and Catalysts. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527635207.ch9.

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Conference papers on the topic "Ligands"

1

Puchta, Ralph, and Dušan Ćoćić. "IRM@Be2+ – quantum chemistry between Bavaria and Šumadija." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.053p.

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Quantum chemical (density functional theory) mechanistic investigations on ligand exchange reactions at a tetrahedrally-coordinated dicationic Beryllium center offer a harmless and alternative way to learn about the traversed reaction pathways compared to experimental studies. Calculations for solvent exchange at [Be(H2O)4]2+, [Be(NH3)]2+, and [Be(HCN)4]2+ showed interchange (I) type mechanisms. To learn about the potential influences of spectator ligands we calculated the water exchange at [Be(L)(H2O)3]n+ (L: neutral ligands, mono-anionic ligands or cationic ligands) and got again consequentl

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Al-Matarneh, Maria-Cristina, Sergiu Sova, Alina Florica Nicolescu, and Ramona Danac. "Synthesis of new zinc and copper complexes derived from bistriazolic ligands." In Conferința științifică națională cu participare internațională "Integrare prin cercetare și inovare", dedicată Zilei Internaționale a Științei pentru Pace și Dezvoltare. Moldova State University, 2025. https://doi.org/10.59295/spd2024n.70.

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The objective of the study consisted in the synthesis of ligands containing a biphenyl nucleus grafted with various 1,2,3-triazole units, as well as their coordination polymers. Thus, the synthesis and characterization of new ligands based on 1,1"-(3,3"-dimethoxy-[1,1"-biphenyl]-4,4"-dil)-bis(4-butyl-1H -1,2,3-triazole) (L1) and 1,1"-(3,3"-dimethoxy-[1,1"-biphenyl]-4,4"-dil)-bis(4-phenyl-1H -1,2,3-triazole) (L2), as well as their coordination polymers with Cu(II) and Zn(II). Also, an unexpected coordination polymer with Cu(I) was obtained in the case of ligand L2, starting from Cu(II). The lig

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Dzichenka, Yaraslau, Michail Shapira, Sergei Usanov, et al. "NOVEL LIGANDS OF HUMAN CYP7 ENZYMES – POSSIBLE MODULATORS OF CHOLESTEROL BLOOD LEVEL: COMPUTER SIMULATION STUDIES." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.435d.

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Our in vitro studies showed that a couple of perspective steroidal derivatives showed previously biomedical potential via enzyme inhibition, receptor binding or antiproliferative effect against the cancer cells of reproductive tissues are able to bind to human CYP7 enzymes – key enzymes taking part in hydroxylation of cholesterol, 25-, 27-hydroxycholesterol and a number of steroidal hormones. In silico screening of binding affinity of the modified steroids toward CYP7 enzymes showed that interaction energy for the new ligands is comparable with consequent values, calculated for the ‘essential’

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Murade, Chandrashekhar U., and George T. Shubeita. "Detecting DNA-Ligand Electrostatic Interactions With a FRET-Based Probe." In 3D Image Acquisition and Display: Technology, Perception and Applications. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/3d.2022.jw5d.5.

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DNA-ligand interactions are dominated by electrostatics as DNA is a highly charged molecule at physiological conditions. Here, we present a FRET-based sensor which can optically report on these interactions between DNA and charged ligands.

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Gao, Yandong, Dana Brantley-Sieders, Devi Majumdar, Jin Chen, Donna Webb, and Deyu Li. "A Simple Approach to Probe the Extracellular Signaling Pathways Using Ligand Traps." In ASME 2012 Third International Conference on Micro/Nanoscale Heat and Mass Transfer. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/mnhmt2012-75106.

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Cells communicate with one another through a huge variety of extracellular soluble signaling molecules. A common method in biology to investigate the signaling pathways is to inactivate the gene coding the interested ligand or receptor from cells using modern DNA technology, known as gene knockout. Even though very effective, however, gene knockout is a time-consuming and cost-prohibitive process and requires huge amount of efforts to conduct. Here we present a simple method to probe the extracellular signaling pathways through engineering a semi-permeable barrier between two cell populations.

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Slater, John H., Jordan S. Miller, Shann S. Yu, and Jennifer L. West. "Multifaceted Nano- and Micropatterned Surfaces for Cell Adhesion Manipulation." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13177.

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Surfaces displaying nano- and micropatterned cell adhesive ligands have led to numerous discoveries in cell biology. Soft lithography techniques such as microcontact printing are well suited for creating surfaces displaying micropatterns of one ligand type in a single arrangement but are difficult to implement for the creation of multifaceted surfaces that present multiple ligand types with each ligand confined to their own pattern. To better understand the influence of extracellular matrix (ECM) composition on adhesion site formation and gross cell behavior (motility, proliferation, different

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Chesla, Scott E., Bryan T. Marshall, and Cheng Zhu. "Measuring the Probability of Receptor Extraction From the Cell Membrane." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-0262.

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Abstract Recently, there has been an increasing interest in measuring the interaction forces between cell adhesion receptors and their ligands [1–3]. These molecules are either anchored on the membrane of a cell or coated on the surface of a substratum. The two surfaces are joined together as a result of the formation of non-covalent bonds between the receptors and ligands. The forces are measured when the two surfaces are separated. In a theoretical paper published nineteen years ago, George Bell estimated the force required to break a receptor-ligand bond and that required to uproot the rece

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Christensen, Ulla. "Kinetics of piasminogen-activation. Effects of ligands binding to the AH-site of plasminogen." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644420.

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Detailed kinetic studies of the urokinase catalysed conversion of Lys-77- and Val-440-plasminogens in the presence and absence of ligands binding to the AH-site of the plasminogens shows that the effects of such ligand-binding correspond with a model of the activation reaction in which the effective Km and kc decreases, but kc/Km increases when the ligands bind. Apparently plasminogen with a free AH-site is a less specific substrate for urokinase, than is plasminogen with an AH-site-bound ligand.The AH-site is a weak lysine binding site of plasminogen located in the mini plasminogen part (Val-

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Timkin, Pavel, E. Timofeev, A. Chupalov, and Evgeniy Borodin. "ANALYSIS AND SELECTION OF LIGANDS FOR TRPM8 USING HARD DOCKING AND MACHINE LEARNING." In XIV International Scientific Conference "System Analysis in Medicine". Far Eastern Scientific Center of Physiology and Pathology of Respiration, 2020. http://dx.doi.org/10.12737/conferencearticle_5fe01d9b233509.17835494.

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In this work, using the in-silico experiment modeling method, the receptor and its ligands were docked in order to obtain the data necessary to study the possibility of using machine learning and hard intermolecular docking methods to predict potential ligands for various receptors. The protein TRPM8 was chosen, which is a member of the TRP superfamily of proteins and its classic agonist menthol as a ligand. It is known that menthol is able to bind to tyrosine 745 of the B chain. To carry out all the manipulations, we used the Autodock software and a special set of graphic tools designed to wo

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Alper, Joshua, Aaron Schmidt, and Kimberly Hamad-Schifferli. "Thermal Transport From Gold Nanorod to Solvent, an Investigation of Ligand Effects by Ultrafast Laser Spectroscopy." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-67266.

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To facilitate analysis of nanoscale heat transfer in nanoparticle systems the thermal properties of ligand layers must be understood. To this end, we use an optical pump-probe technique to study the thermal transport across ligands on gold nanorods and into the solvent. We find that varying properties of the ligand can have large impacts on the thermal decay of a nanorod after exposure to a laser pulse. By raising the concentration of free CTAB from 1 mM and 10 mM in solutions, the CTAB layer’s effective thermal interface conductance increases three fold. The transition occurs near the CTAB cr

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Reports on the topic "Ligands"

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Potts, K. Macrocyclic ligands for uranium complexation. Office of Scientific and Technical Information (OSTI), 1990. http://dx.doi.org/10.2172/7201376.

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Muenchausen, Ross. MACROCYCLIC LIGANDS AND THEIR COMPLEXES. Office of Scientific and Technical Information (OSTI), 2020. http://dx.doi.org/10.2172/1893650.

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Walensky, Justin. Exploring Covalency in the Actinides Using Soft Donor-Based Ligands and Metal-Ligand Multiple Bonding. Office of Scientific and Technical Information (OSTI), 2021. http://dx.doi.org/10.2172/1782213.

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Goodrich, Jennifer S. EGFR Activation by Spatially Restricted Ligands. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada426969.

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Kung, H. F. Receptor Specific Ligands for Spect Imaging. Office of Scientific and Technical Information (OSTI), 2003. http://dx.doi.org/10.2172/836898.

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Sachs, Frederick. Ligands for Stretch Activated Ion Channels. Defense Technical Information Center, 1996. http://dx.doi.org/10.21236/ada315807.

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Mukherjee, Sayan, Noor U. Din Reshi, and Jitendra K. Bera. Asking Ligands to Lend a Hand. The Israel Chemical Society, 2023. http://dx.doi.org/10.51167/acm00039.

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Lehnert, B., and D. Allen. Targeted in vitro evolution of protein ligands. Office of Scientific and Technical Information (OSTI), 2000. http://dx.doi.org/10.2172/767437.

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Cutler, A. R. Selective transformation of carbonyl ligands to organic molecules. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/5021885.

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Paine, Robert T. Preorganized and Immobilized Ligands for Metal Ion Separations. Office of Scientific and Technical Information (OSTI), 2015. http://dx.doi.org/10.2172/1236699.

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