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Journal articles on the topic 'LILR'

Author: Grafiati

Published: 11 September 2021

Last updated: 17 July 2025

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1

Person, Anthony, Wendy Xiong, Christian Erickson, et al. "Angiopoietins and angiopoietin-like proteins bind to LILRA/B receptors and activate innate immune responses in human monocytes (INC1P.405)." Journal of Immunology 194, no. 1_Supplement (2015): 54.26. http://dx.doi.org/10.4049/jimmunol.194.supp.54.26.

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Abstract Angiopoietins and Angiopoietin-like (ANGPTL) proteins are secreted glycoproteins that play multiple roles in angiogenesis, lipid metabolism, hematopoietic stem cell expansion, and inflammation. Unlike Angiopoietins, which are known to signal through the tyrosine kinase Tie1 or Tie2 receptors, ANGPTL proteins have long been considered orphan ligands. Recently, ANGPTL1, 2, 5, and 7 were shown to bind to human leukocyte immunoglobulin like receptor B2 (LILRB2), resulting in enhancement of human haematopoietic stem cell proliferation and expansion. Leukocyte immunoglobulin-like receptors

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2

Pilsbury, Louise E., Rachel L. Allen, and Martin Vordermeier. "Modulation of Toll-Like Receptor Activity by Leukocyte Ig-Like Receptors and Their Effects during Bacterial Infection." Mediators of Inflammation 2010 (2010): 1–9. http://dx.doi.org/10.1155/2010/536478.

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Toll-like receptors (TLRs) are a potent trigger for inflammatory immune responses. Without tight regulation their activation could lead to pathology, so it is imperative to extend our understanding of the regulatory mechanisms that govern TLR expression and function. One family of immunoregulatory proteins which can provide a balancing effect on TLR activity are the Leukocyte Ig-like receptors (LILRs), which act as innate immune receptors for self-proteins. Here we describe the LILR family, their inhibitory effect on TLR activity in cells of the monocytic lineage, their signalling pathway, and

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Wicher, Krzysztof B., Moritz Haneklaus, Martha Lopez-Yrigoyen, et al. "Abstract LB040: MACO-355, a unique pan-LILR monoclonal antibody for cancer therapy, re-programs and stimulates immuno-suppressive macrophages in a novel ligand-binding blocking independent manner." Cancer Research 84, no. 7_Supplement (2024): LB040. http://dx.doi.org/10.1158/1538-7445.am2024-lb040.

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Abstract Macrophages populate most solid tumors in large numbers and limit effective anti-tumoral immune responses. The leukocyte immunoglobulin-like receptors (LILR) such as e.g. LILRB1, LILRB2, and others are expressed on tumor associated macrophages. Despite sharing multiple ligands such as major histocompatibility complex class I G (HLA-G), these receptors regulate different macrophage functions such as phagocytosis or cytokine release. To date, therapeutic approaches to targeting LILRs have concentrated on blocking receptor-ligand interactions to relieve ligand-mediated immune suppression

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4

Deryuginа, A. V., M. N. Ivashchenko, M. N. Talamanova, V. A. Petrov, D. A. Erobkina, and A. A. Kustova. "The influence of low-intensity laser radiation on the blood parameters of cows under technological stress." Вестник российской сельскохозяйственной науки, no. 6 (December 15, 2023): 95–99. http://dx.doi.org/10.31857/2500-2082/2023/6/95-99.

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The study of clinical-hematologic parameters under technological stress at cows and the effect of low-intensity laser radiation (LILR) under technological stress was carried out. The study was carried out on high-yielding Holstein black-breed cows which were modeled technological stress and subsequently exposed to LILR on the withers or ear with exposure time of 5 or 15 depending on the group of animals. LILR with a wavelength of 830 nm was used. The study of hematological parameters of blood under technological stress in animals showed an increase in the number of leukocytes up to 14 days, a

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5

Yamazaki, Rika, Atsushi Furukawa, Kouyuki Hirayasu, et al. "Molecular mechanism of the recognition of bacterially cleaved immunoglobulin by the immune regulatory receptor LILRA2." Journal of Biological Chemistry 295, no. 28 (2020): 9531–41. http://dx.doi.org/10.1074/jbc.ra120.013354.

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Human leukocyte immunoglobulin-like receptors (LILRs) typically regulate immune activation by binding to the human leukocyte antigen class I molecules. LILRA2, a member of the LILR family, was recently reported to bind to other unique ligands, the bacterially degraded Igs (N-truncated Igs), for the activation of immune cells. Therefore, LILRA2 is currently attracting significant attention as a novel innate immune receptor. However, the detailed recognition mechanisms required for this interaction remain unclear. In this study, using several biophysical techniques, we uncovered the molecular me

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Gomes Cardoso Gastaldi, Gabriela, Juliana Paula de Oliveira, Jorge Vicente Lopes da Silva, Rodrigo Alvarenga Rezende, and André Capaldo Amaral. "PHOTOBIOMODULATORY EFFECT OF LOW-INTENSITY LASER RADIATION ON MULTICELLULAR SPHEROIDS." Revista Brasileira Multidisciplinar 24, no. 2 (2021): 156–67. http://dx.doi.org/10.25061/2527-2675/rebram/2021.v24i2.1136.

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Photobiomodulatory effects of low-intensity laser radiation (LILR) in cells cultured in standard, two-dimensional conditions are well established. Conversely, the characteristics of this effect in three-dimensional (3D) cultures, which are currently recommended due to the greater similarity with cellular behavior in vivo, have not yet been widely investigated. The objective of this work was to analyze the biomodulator effect of LILR, on the wavelength (λ) of 685 nm, on the constitution process and on the viability of cells cultured as multicellular spheroid (MSs). For this, agarose molds conta

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Kulikova, Nataliya Gennadievna, Zaur Gidovich Zhilokov, Albina Sergeevna Tkachenko, and Tinatin Chkheidze. "On the use of laser therapy in dentistry." Fizioterapevt (Physiotherapist), no. 01 (January 13, 2022): 33–40. http://dx.doi.org/10.33920/med-14-2202-04.

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The aim of the research: to optimize the prevention of dental complications by using electromagnetic low-intensity laser radiation (LILR) techniques on dental and periodontal tissues. Research methods. In 138 dental patients, a clinical and functional assessment of the dental apparatus was carried out, dental indices were studied, the results of vascular endothelial parameters (VEGF-A, sVEGF-R1, sVEGF-R2) and immune parameters (FNF, TNF, IFN-γ, neutrophils) of blood serum (solid-phase enzyme immunoassay with a standard set), as well as VAS pain syndrome parameters were analyzed before/after la

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8

Bakhritdinova, Fazilat. "Dynamics of cytological parameters of the conjunctiva in the course of a complex treatment of eye burns using a low-intensity laser radiation." Eye 127, no. 2019-3 (2019): 7–11. http://dx.doi.org/10.33791/2222-4408-2019-3-7-11.

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Purpose: A cytological assessment of the effectiveness of eye burns complex treatment using low-intensity infrared laser radiation (LILR) was performed. Material and methods. 42 patients (64 eyes) with eye burns of different etiology and severity were examined. For the patients of the main group (21 patients, 30 eyes) low-intensity infrared laser radiation was added to the traditional treatment methods. Results. Decrease in the number of basophils and the amount of exudation during the inflammatory process indicated the suppression of the initial forms of inflammatory mediators – histamine and

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Heinig, Kristina, Christina A. Hartl, Marisa Stebegg-Wagner, et al. "Abstract 2237: IOMX-0675, a LILRB1/LILRB2 cross-specific antibody that repolarizes the tumor microenvironment to drive potent anti-tumor activity." Cancer Research 85, no. 8_Supplement_1 (2025): 2237. https://doi.org/10.1158/1538-7445.am2025-2237.

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Abstract IOMX-0675 is a monoclonal immunoglobulin G1 (IgG1) antibody targeting LILRB1 (ILT2) and LILRB2 (ILT4), key immunosuppressive receptors of the leukocyte immunoglobulin-like receptor (LILR) family, that play a pivotal role in tumor immune evasion. LILRB1 and LILRB2 recognize both classical and non-classical MHC-I molecules and are highly expressed on tumor-infiltrating myeloid cells, with LILRB1 also found on lymphoid cells. Their frequently observed upregulation in patients non-responsive to T cell checkpoint blockade, implicate a role in driving tumor resistance. Expression profiling

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10

Bhattacharya, A., K. Kizer, R. Suseno, et al. "LILR full gene variation in European and African American cohorts." Human Immunology 85 (September 2024): 110880. http://dx.doi.org/10.1016/j.humimm.2024.110880.

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Hartl, Christina, Jonas Zantow, Ilona-Petra Maser, et al. "Abstract 1362: IOMX-0675, a LILRB1 and LILRB2 cross-specific antibody, effectively repolarizes immunosuppressive myeloid cells and activates T cells leading to potent tumor cell killing." Cancer Research 84, no. 6_Supplement (2024): 1362. http://dx.doi.org/10.1158/1538-7445.am2024-1362.

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Abstract Recently, myeloid checkpoints in the tumor microenvironment have gained increased attention in the context of tumor immune evasion. LILRB1 (ILT2) and LILRB2 (ILT4) are immunosuppressive receptors of the leukocyte immunoglobulin-like receptor (LILR) family that recognize both classical and non-classical MHC-I molecules (e.g., HLA-G). While tumor-infiltrating myeloid cells express both LILRB1 and LILRB2, lymphoid cells are restricted to LILRB1 expression. LILRB1 and LILRB2 are frequently co-expressed with immune-activating LILR family members LILRA1 and LILRA3 in several tumor indicatio

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Creutzburg, S., L. van de Pasch, S. Stokman, et al. "LILR and LAIR gene capture for long read sequencing-based typing." Human Immunology 85 (September 2024): 110884. http://dx.doi.org/10.1016/j.humimm.2024.110884.

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13

Шабалин, В. В., С. Н. Шатохина, А. А. Кубатиев та В. Н. Шабалин. "Структурный отклик сыворотки крови человека на воздействие электромагнитных излучений низкой интенсивности". ZHurnal «Patologicheskaia fiziologiia i eksperimental`naia terapiia», № 4() (21 листопада 2018): 98–103. http://dx.doi.org/10.25557/0031-2991.2018.04.98-103.

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Цель работы: исследование характера отклика сыворотки крови больных и здоровых людей на внешнее электромагнитное воздействие. Методика. Исследована сыворотка крови 130 пациентов с различными видами патологии и 30 здоровых доноров на внешнее электромагнитное излучение (ЭМИ). Применялось ЭМИ крайне высокой частоты (КВЧ), низкоинтенсивного лазерного излучения (НИЛИ), а также сочетанного применения двух источников ЭМИ (НИЛИ и КВЧ) на сыворотку крови. Оценка эффекта ЭМИ осуществлялась по структурам твёрдой фазы (фациям) сыворотки крови, получаемым методом клиновидной дегидратации. Метод состоял в н

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Hartl, Christina A., Kristina Heinig, Marisa Stebegg-Wagner, et al. "Abstract A095: IOMX-0675, a cross-specific antibody selectively blocking LILRB1 and LILRB2, robustly repolarizes immunosuppressive myeloid cells and stimulates cytotoxic T cells." Cancer Immunology Research 13, no. 2_Supplement (2025): A095. https://doi.org/10.1158/2326-6074.io2025-a095.

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Abstract The role of myeloid checkpoints in enabling tumors to evade immune responses has gained increased attention recently. LILRB1 (ILT2) and LILRB2 (ILT4) are immunosuppressive receptors in the leukocyte immunoglobulin-like receptor (LILR) family that bind classical and non-classical MHC-I molecules, such as HLA-G. Myeloid cells in the tumor microenvironment express both LILRB1 and LILRB2, while lymphoid cells only express LILRB1. High levels of LILRB1 and LILRB2 are often seen in patients who do not respond to T cell checkpoint inhibitors, suggesting these receptors may drive tumor resist

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15

Brown, D., J. Trowsdale, and R. Allen. "The LILR family: modulators of innate and adaptive immune pathways in health and disease." Tissue Antigens 64, no. 3 (2004): 215–25. http://dx.doi.org/10.1111/j.0001-2815.2004.00290.x.

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16

Kurbanova, A. Yu, V. I. Egorov, I. A. Vasilenko, G. A. Golubovskii, and D. V. Kassina. "Integrated approach in conservative treatment of chronic tonsillitis." Russian Otorhinolaryngology 22, no. 6 (2023): 62–72. http://dx.doi.org/10.18692/1810-4800-2023-6-62-72.

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Chronic tonsillitis (CT) is one of the most common diseases among the pathologies of the ENT organs; in outpatient practice, its share ranges from 4% to 35%. The palatine tonsils (PT) are participants in cellular and humoral immunity. It is important to develop new therapeutic approaches that most effectively influence the tissue focus of inflammation. The attention of clinicians is drawn to the use of physiotherapeutic methods of treating CT. Data were obtained on the ability of nitric oxide (NO) to penetrate deep into tissue through intact skin and mucous membranes. We hypothesized that incl

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Masuda, Ai, Akira Nakamura, Tsutomu Maeda, Yuzuru Sakamoto, and Toshiyuki Takai. "Cis binding between inhibitory receptors and MHC class I can regulate mast cell activation." Journal of Experimental Medicine 204, no. 4 (2007): 907–20. http://dx.doi.org/10.1084/jem.20060631.

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Allergy is caused by immune effector cells, including mast cells and basophils. Cellular signaling that activates these effector cells is regulated by different inhibitory receptors on their surface. We show that human leukocyte immunoglobulin (Ig)-like receptor (LILR) B2 and its mouse orthologue, paired Ig-like receptor (PIR)–B, constitutively associate to major histocompatibility complex (MHC) class I on the same cell surface (in cis). The IgE-mediated effector responses were augmented in β2-microglobulin (β2m) and PIR-B–deficient mast cells. In addition, the increased cytokine production of

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18

Nimmerjahn, F., and A. Lux. "LILR-B1 blocks activating Fc R signaling to allow antibody dependent enhancement of dengue virus infection." Proceedings of the National Academy of Sciences 111, no. 7 (2014): 2404–5. http://dx.doi.org/10.1073/pnas.1324286111.

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19

López-Álvarez, María R., Des C. Jones, Wei Jiang, James A. Traherne, and John Trowsdale. "Copy number and nucleotide variation of the LILR family of myelomonocytic cell activating and inhibitory receptors." Immunogenetics 66, no. 2 (2013): 73–83. http://dx.doi.org/10.1007/s00251-013-0742-5.

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20

Huang, Jinghe, Patrick S. Burke, Thai Duong Hong Cung, et al. "Leukocyte Immunoglobulin-Like Receptors Maintain Unique Antigen-Presenting Properties of Circulating Myeloid Dendritic Cells in HIV-1-Infected Elite Controllers." Journal of Virology 84, no. 18 (2010): 9463–71. http://dx.doi.org/10.1128/jvi.01009-10.

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ABSTRACT Elite controllers maintain undetectable levels of HIV-1 replication in the absence of antiretroviral therapy, but the correlates of immune protection in this patient population are ill defined. Here, we demonstrate that in comparison to patients with progressive HIV-1 infection or healthy persons not infected with HIV-1, elite controllers have circulating myeloid dendritic cells with significantly increased antigen-presenting properties, while their ability to secrete proinflammatory cytokines is substantially diminished. This unique functional profile is associated with a distinct su

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McIntire, R. H., T. Sifers, J. S. Platt, K. G. Ganacias, D. K. Langat, and J. S. Hunt. "Novel HLA-G-Binding Leukocyte Immunoglobulin-Like Receptor (LILR) Expression Patterns in Human Placentas and Umbilical Cords." Placenta 29, no. 7 (2008): 631–38. http://dx.doi.org/10.1016/j.placenta.2008.04.007.

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SHIROISHI, Mitsunori, Kimiko KUROKI, Daisuke KOHDA, and Katsumi MAENAKA. "Entropically Driven Receptor-Ligand Interaction; Molecular Recognition of Human Inhibitory Receptor Leukocyte Immunoglobulin-Like Receptors (LILRs)." Seibutsu Butsuri 47, no. 2 (2007): 093–99. http://dx.doi.org/10.2142/biophys.47.093.

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Arosa, Fernando A., André J. Esgalhado, Débora Reste-Ferreira, and Elsa M. Cardoso. "Open MHC Class I Conformers: A Look through the Looking Glass." International Journal of Molecular Sciences 22, no. 18 (2021): 9738. http://dx.doi.org/10.3390/ijms22189738.

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Studies carried out during the last few decades have consistently shown that cell surface MHC class I (MHC-I) molecules are endowed with functions unrelated with antigen presentation. These include cis–trans-interactions with inhibitory and activating KIR and LILR, and cis-interactions with receptors for hormones, growth factors, cytokines, and neurotransmitters. The mounting body of evidence indicates that these non-immunological MHC-I functions impact clinical and biomedical settings, including autoimmune responses, tumor escape, transplantation, and neuronal development. Notably, most of th

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Nagasaki, M., K. Hirayasu, S. Khor, Y. Kawai, and K. Tokunaga. "JoGo-LILR caller: Unveiling and navigating the diversity of LILRB3-LILRA6 copy number structures with whole-genome sequencing." Human Immunology 85 (September 2024): 111024. http://dx.doi.org/10.1016/j.humimm.2024.111024.

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Young, Neil T., Edward C. P. Waller, Rashmi Patel, Ali Roghanian, Jonathan M. Austyn, and John Trowsdale. "The inhibitory receptor LILRB1 modulates the differentiation and regulatory potential of human dendritic cells." Blood 111, no. 6 (2008): 3090–96. http://dx.doi.org/10.1182/blood-2007-05-089771.

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Abstract Dendritic cells (DCs) link innate and adaptive immunity, initiating and regulating effector cell responses. They ubiquitously express members of the LILR (ILT, LIR, CD85) family of molecules, some of which recognize self-HLA molecules, but little is known of their possible functions in DC biology. We demonstrate that the inhibitory receptor LILRB1 (ILT2, LIR1, CD85j) is selectively up-regulated during DC differentiation from monocyte precursors in culture. Continuous ligation of LILRB1 modulated cellular differentiation, conferred a unique phenotype upon the resultant cells, induced a

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Belaunzaran, Osiris Marroquin, Anahita Rafiei, Anil Kumar, et al. "216 Anti-tumor activity of iosH2 by blocking LILRB2 receptor signalling." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (2020): A235. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0216.

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BackgroundThe human leukocyte immunoglobulin-like receptor family B (LILR B) acts as check point blockade of the innate immune system by inhibiting leukocyte activation through SHP phosphatase recruitment. Some of the physiological ligands include classical HLA class I molecules, including beta-2-microglobulin (B2M) free open conformers (OC). Natural HLA-OC expression is known from autoimmune disease leading to immune activation by pleiotropic effects since they bind to LILRB and KIR family members reducing Treg and MDSC numbers and increased effector T-cell and NK-cell activation, respectivel

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Moodie, S. J., P. J. Norman, A. L. King, et al. "Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters." European Journal of Immunogenetics 29, no. 4 (2002): 287–91. http://dx.doi.org/10.1046/j.1365-2370.2002.00313.x.

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Schwartz, John C., and John A. Hammond. "The unique evolution of the pig LRC, a single KIR but expansion of LILR and a novel Ig receptor family." Immunogenetics 70, no. 10 (2018): 661–69. http://dx.doi.org/10.1007/s00251-018-1067-1.

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Nagasaki, Masao, Kouyuki Hirayasu, Seik-Soon Khor, et al. "JoGo-LILR caller: Unveiling and navigating the complex diversity of LILRB3-LILRA6 copy number haplotype structures with whole-genome sequencing." Human Immunology 86, no. 3 (2025): 111272. https://doi.org/10.1016/j.humimm.2025.111272.

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Ravindranath, Mepur H., Narendranath M. Ravindranath, Carly J. Amato-Menker, Fatiha El Hilali та Edward J. Filippone. "Conformational Alterations of the Cell Surface of Monomeric and Dimeric β2m-Free HLA-I (Proto-HLA) May Enable Novel Immune Functions in Health and Disease". Current Issues in Molecular Biology 46, № 7 (2024): 6961–85. http://dx.doi.org/10.3390/cimb46070416.

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Human leukocyte antigens (HLAs) are polymorphic glycoproteins expressed on the cell surface of nucleated cells and consist of two classes, HLA class I and HLA class II. In contrast, in mice, these molecules, known as H-2, are expressed on both nucleated cells and erythrocytes. HLA-I molecules (Face-1) are heterodimers consisting of a polypeptide heavy chain (HC) and a light chain, B2-microglobulin (B2m). The heterodimers bind to antigenic peptides and present them to the T-cell receptors of CD8+ cytotoxic T lymphocytes. The HCs can also independently emerge on the cell surface as B2m-free HC m

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Su, Chen, Yanping Feng, Hui Zhao, et al. "Abstract 592: Therapeutical antibody against LILRB2 enhances antitumor immunity by reprogramming M2 macrophage." Cancer Research 83, no. 7_Supplement (2023): 592. http://dx.doi.org/10.1158/1538-7445.am2023-592.

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Abstract M2 macrophage is critical in maintaining an immune-suppressive microenvironment inside the tumor. Here we developed a LILRB2 antagonist antibody KA-1769 for reprogramming M2 macrophage to M1 phenotype. KA-1769 binds to LILRB2 with higher affinity (KD=0.67nM) than MK-4830 (KD=7.4nM). And it also binds to LILRB1 with weak affinity (KD=41nM) but not to other LILR family members. KA-1769 blocks bindings of HLA-G to both LILRB1 and LILRB2. Macrophage derived from monocyte with M-CSF stimulation polarizes to M1 phenotype in the presence of KA-1769 by increasing expression of CD86, MHCII, an

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Kerkines, Ioannis S. K., та Aristides Mavridis. "Theoretical investigation of theX2Σ+,A2Π, andB2Σ+ states of LiAr and LiKr". Journal of Chemical Physics 116, № 21 (2002): 9305–14. http://dx.doi.org/10.1063/1.1473809.

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Pramanik, Dewi, Nisa Istiqomah, and Liberty Chaidir. "Studi Tingkat Ploidi pada Lili (Lilium sp.) Hasil Kultur Antera Melalui Penghitungan Jumlah Kloroplas dan Kromosom." Jurnal Agro 3, no. 2 (2016): 34–42. http://dx.doi.org/10.15575/864.

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Lili (Lilium sp.) termasuk famili Liliaceae, merupakan tanaman hias yang memiliki nilai ekonomi tinggi karena permintaan konsumen terus meningkat. Permintaan varietas tanaman yang seragam menuntut pengembangan hibrida F1. Perakitan tanaman hibrida dapat dihasilkan melalui pembentukan tanaman haploid. Salah satu metode untuk memproduksi tanaman haploid adalah dengan kultur antera. Pengecekan tanaman hasil kultur antera dapat dilakukan dengan penghitungan jumlah kloroplas dan jumlah kromosom, namun untuk lili hasil belum diperoleh informasi mengenai korelasi antara jumlah kloroplas pada sel penj

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Fibrianty, Eka, and Ridho Kurniati. "Karakterisasi Morfologi dan Hibridisasi Rain Lily (Zephyranthes sp.)." Jurnal Hortikultura Indonesia 13, no. 2 (2022): 81–89. http://dx.doi.org/10.29244/jhi.13.2.81-89.

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Rain lily (Zephyranthes sp) merupakan tanaman hias yang umumnya dibudidayakan sebagai tanaman hias pot dan lanskap. Warna dan bentuk serta ukuran tanaman hias ini masih terbatas. Keragaman genetik dan variasi warna, ukuran dan bentuk tanaman ini dapat ditingkatkan melalui hibridisasi. Penelitian dilakukan di Kebun Percobaan Balai Penelitian Tanaman Hias Cipanas pada bulan April-November 2021. Penelitian ini bertujuan untuk mendapatkan keragaman morfologi dan pembentukan buah Rain lili. Kultivar Rain lili yang digunakan antara lain Zephyranthes rosea, Zephyranthes pulchella, Zephyranthes candid

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Du, Xinyi. "Anxiety, Dilemma and Transcendence - The Case of Lilly's Drawing Process." Communications in Humanities Research 44, no. 1 (2024): 149–55. http://dx.doi.org/10.54254/2753-7064/44/20240083.

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In Virginia Woolf's classic work To the Lighthouse, although Lily is not the main character, the idea of bisexuality embodied in her makes her one of the most important objects in the study of feminist thought. This paper intends to start from the rough painting process of Lily in To the Lighthouse to discover the content of Lily beyond feminist thought. Through the study, it finds that Lili not only symbolizes the beautiful personality of bisexuality, but she is also full of anxiety and dilemmas: the dilemma of the mind when creating, the anxiety about the right of free choice, the anxiety ab

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Du, Xinyi. "Anxiety, Dilemma and Transcendence - The Case of Lilly's Drawing Process." Communications in Humanities Research 36, no. 1 (2024): 158–64. http://dx.doi.org/10.54254/2753-7064/36/20240083.

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In Virginia Woolf's classic work To the Lighthouse, although Lily is not the main character, the idea of bisexuality embodied in her makes her one of the most important objects in the study of feminist thought. This paper intends to start from the rough painting process of Lily in To the Lighthouse to discover the content of Lily beyond feminist thought. Through the study, it finds that Lili not only symbolizes the beautiful personality of bisexuality, but she is also full of anxiety and dilemmas: the dilemma of the mind when creating, the anxiety about the right of free choice, the anxiety ab

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Antipkin, I. I., E. V. Ryazantsev, V. E. Ryazantsev, and A. M. Khoshnaw. "INFLUENCE OF LASER TREATMENT ON INDICATORS OF FREE-RADICAL OXIDATION AND ANTIOXIDANT PROTECTION IN SECONDARY PYELONEPHRITIS." Aspirantskiy Vestnik Povolzhiya 19, no. 1-2 (2019): 149–56. http://dx.doi.org/10.17816/2072-2354.2019.19.1.149-156.

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Relevance. Optimization of the conservative tactics of acute inflammation of the kidney in nephrolithiasis makes it advisable to use non-traditional methods of detoxification low-intensity laser radiation (LILR) in particular. Aim. To evaluate the effectiveness of laser therapy (LT) in the complex correction of acute secondary pyelonephritis (ASP) in patients with single kidney stones according to the basic adaptation criteria of oxidative-antioxidant clinical medicine КЛИНИЧЕСКАЯ МЕДИЦИНА homeostasis of the organism. Materials and methods. Indices of endogenous intoxication (EI), characterizi

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Peng, YuFeng, Annum Munir, and Meijuan Zhang. "Abstract A045: PSB120, a LILRB2 specific antibody enhances sensitivity to Gemcitabine through an HLA-G independent mechanism." Cancer Immunology Research 12, no. 10_Supplement (2024): A045. http://dx.doi.org/10.1158/2326-6074.tumimm24-a045.

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Abstract The suppressive micro-environment within tumors is partly caused by infiltrating macrophages. Expression of HLA-G on tumor cells and its receptor LILRB2 on tumor macrophages are associated with poor prognosis in cancer patients. Anti LILRB2 antibodies have been developed to block HLA-G and LILRB2 interaction and to promote M1 macrophage differentiation. Whether anti LILRB2 antibody can exert its effect through an HLA-G independent mechanism has not been investigated. Here, we describe PSB120, a fully humanized anti LILRB2 antibody with high affinity to LILRB2 without cross-reactivity

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Nina Meliana and Siti Jaenah. "Penerapan Metode ABC Dalam Sistem Informasi Manajemen Persediaan Pada Toko Lily Jaya." Jurnal Ilmiah Betrik 13, no. 2 (2022): 180–90. http://dx.doi.org/10.36050/betrik.v13i2.512.

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Pengelolaan persediaan barang di Toko Lily Jaya saat ini hanya mencatat persediaan barang masuk dan barang keluar, belum dapat memberikan informasi barang yang paling banyak dibutuhkan dan yang tidak banyak dibutuhkan, berapa banyak permintaan dari setiap pengguna dan siapa saja pengguna yang paling banyak melakukan permintaan barang di Toko Lily Jaya. Permasalahan tersebut disebabkan belum diterapkannya metode dalam pengendalian barang. Tujuan penelitian ini memberikan solusi melalui pengkajian beberapa teori dan observasi di lapangan dalam rangka perancangan sistem informasi manajemen persed

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Frantz, Simon. "Liar liar." Nature Reviews Molecular Cell Biology 3, no. 2 (2002): 3–4. http://dx.doi.org/10.1038/nrm725.

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Carson, Thomas. "Liar Liar." International Journal of Applied Philosophy 22, no. 2 (2008): 189–210. http://dx.doi.org/10.5840/ijap200822215.

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Wilson, Rick K., and Jane Sell. "“Liar, Liar... ”." Journal of Conflict Resolution 41, no. 5 (1997): 695–717. http://dx.doi.org/10.1177/0022002797041005005.

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Robson, David. "Liar liar." New Scientist 266, no. 3542 (2025): 43. https://doi.org/10.1016/s0262-4079(25)00755-9.

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Budiarto, Kurniawan, Indijarto Budi Raharjo, Hanudin Hanudin, and Wakiah Nuryani. "Konservasi in vitro dua aksesi lili mealui modifikasi media kultur." Jurnal Agro 7, no. 1 (2020): 1–13. http://dx.doi.org/10.15575/4179.

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Konservasi in vitro merupakan salah satu alternatif penyimpanan materi genetik dalam kondisi aseptik. Metode ini dapat mengurangi resiko kepunahan materi genetik akibat kondisi lingkungan yang ekstrem dan kerumitan pengelolaan pada skala in vivo terutama untuk tanaman yang berasal dari subtropis, seperti lili. Metode penghambatan pertumbuhan dan ketahanan plantlet selama perlakuan konservasi merupakan faktor penting untuk kelangsungan hidup materi genetik yang disimpan. Penelitian bertujuan untuk mengevaluasi media konservasi melalui modifikasi kandungan nutrien dan konsentrasi sukrosa untuk k

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Costa, Maria Jose, Ryan Stafford, Zhiqiang Ku, et al. "686 Preclinical characterization of a novel therapeutic antibody targeting LILRB2." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (2020): A725. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0686.

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BackgroundMyeloid-derived suppressor cells and tumor-associated macrophages inhibit anti-cancer immune responses systemically and in the tumor microenvironment, respectively, thereby limiting the efficacy of immune checkpoint blockers.1–5 However, the plasticity of myeloid cells may enable therapeutic intervention. The inhibitory receptor LILRB2/ILT4, which is expressed primarily in myeloid cells (monocytes, macrophages, dendritic cells and neutrophils), has emerged as a key immune checkpoint mediating the tolerogenic activity of myeloid cells associated with cancer.6–8 LILRB2/ILT4 has several

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Azinović, D., S. Milosević, G. Pichler, M. C. van Hemert, and R. Düren. "LiAr, LiKr and LiXe excimers: Photochemical formation of the $\mathsf3^{2}\Sigma^{+} $ - $\mathsf1^{2}\Sigma ^{+}$ bands." European Physical Journal D - Atomic, Molecular and Optical Physics 6, no. 3 (1999): 333–41. http://dx.doi.org/10.1007/s100530050317.

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Davis, Carol V. "Carnation, Lily, Lily, Rose." Prairie Schooner 81, no. 2 (2007): 115. http://dx.doi.org/10.1353/psg.2007.0121.

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Quinn, Elizabeth. "Child behaviour LIAR LIAR." Early Years Educator 1, no. 1 (1999): 53–54. http://dx.doi.org/10.12968/eyed.1999.1.1.15831.

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Sun, Ao, Enlin Zheng, Huili Cao, et al. "Abstract 6384: ATG-034, an LILRB4 antagonist antibody, reinvigorates dendritic cells and prevents tumor progression." Cancer Research 83, no. 7_Supplement (2023): 6384. http://dx.doi.org/10.1158/1538-7445.am2023-6384.

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Abstract Background: Dendritic cells (DCs) are vital for initiating antigen-specific T cell-dependent antitumor immune responses. However, emerging evidence reveals that local DCs within the tumor microenvironment (TME) are tolerized to facilitate immune evasion. Reprogramming of DCs is recognized as a promising strategy for tumor immunotherapy. Leukocyte immunoglobulin-like receptor B4 (LILRB4) is an inhibitory receptor belonging to the LILR family which is mainly expressed on normal myeloid cells and myeloid-derived malignant cells. It is upregulated on tolerogenic DCs (tolDCs), which exhibi

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Goncharova, I. A., A. A. Zarubin, N. P. Babushkina, I. A. Koroleva, and M. S. Nazarenko. "Changes in DNA methylation profile in liver tissue during progression of HCV-induced fibrosis to hepatocellular carcinoma." Vavilov Journal of Genetics and Breeding 27, no. 1 (2023): 72–82. http://dx.doi.org/10.18699/vjgb-23-10.

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In this study we compared methylation levels of 27,578 CpG sites between paired samples of the tumor and surrounding liver tissues with various degrees of damage (fibrosis, cirrhosis) in HCV-induced hepatocellular carcinoma (HCC) patients, as well as between tumor and normal tissue in non-viral HCC patients, using GSE73003 and GSE37988 data from GEODataSets (https://www.ncbi.nlm.nih.gov/). A significantly lower number of differentially methylated sites (DMS) were found between HCC of non-viral etiology and normal liver tissue, as well as between HCC and fibrosis (32 and 40), than between HCC a

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