Academic literature on the topic 'Linearity and Precision'

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Journal articles on the topic "Linearity and Precision"

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Kroll, M. H., and K. Emancipator. "A theoretical evaluation of linearity." Clinical Chemistry 39, no. 3 (1993): 405–13. http://dx.doi.org/10.1093/clinchem/39.3.405.

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Abstract The measure of linearity is an important part of the evaluation of a method. According to the NCCLS guidelines (Document EP6-P), results of a linearity experiment are fit to a straight line and judged linear either by visual evaluation, which is subjective, or by the lack-of-fit test. This approach depends on the precision of the method, is not necessarily conclusive, and fails to be quantitative. We define linearity as a measure of how well a first-order (linear) polynomial fits the data compared with a higher-order (nonlinear) polynomial. The major property of a linear polynomial is
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Tartari, Gabriele A., Aldo Marchetto, and Rosario Mosello. "Precision and linearity of inorganic analyses by ion chromatography." Journal of Chromatography A 706, no. 1-2 (1995): 21–29. http://dx.doi.org/10.1016/0021-9673(94)01222-z.

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Zwinkels, Joanne C., and D. S. Gignac. "Automated high precision variable aperture for spectrophotometer linearity testing." Applied Optics 30, no. 13 (1991): 1678. http://dx.doi.org/10.1364/ao.30.001678.

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Desh, Raj Singh, K. Jain Sachin, and Vengurlekar Sudha. "Validation of spectrometric method for the determination of assay of terbinafine hydrochloride drug substance." Chemistry Research Journal 9, no. 2 (2024): 77–88. https://doi.org/10.5281/zenodo.11281809.

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<strong>Abstract </strong> The proposed RP- HPLC method has the advantages of sensitivity, simplicity, precision, accuracy and convenience for the separation and quantization of terbinafine hydrochloride in tablet dosage form. The method was carried out using Zodiac C18 column (100 X 4.6 mm, 5&mu;) with mobile phase comprised of methanol: acetonitrilein the ratio of 60:40 (v/v/v). The flow rate was set at 1.5ml/min and effluent was detected at 220nm. Under these conditions the retention time of terbinafine hydrochloride was found to be 3.57minute. The method was validated for specificity, accu
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Ranjith, Kumar, Kumar Ramaiah Siva, and Rao Madhusudhan. "Development of HPLC method for estimation of Ambrisentan from Immediate release tablets." American Journal of PharmTech Research 12, no. 3 (2022): 169–78. https://doi.org/10.5281/zenodo.6984393.

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ABSTRACT The aim of the present work was to develop and validate a simple and efficient method for the analysis of Ambrisentan in pharmaceutical dosage forms by reverse phase high pressure liquid chromatography. A stainless steel column 150 mm long, 4.6 mm internal diameter filled with octasilyl silica chemically bonded with silica gel particles of 5 mm diameter was used for elution. The retention time of Ambrisentan was 4.451 min. The method showed a good linearity in the concentration range of 12.5-250 &micro;g/mL with a correlation coefficient of 1.000. The validation characteristics includ
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Prathap, VR, Kumar Ramaiah Siva, and Madhusudhan Rao Y. "Development of A New RP-HPLC Method For Estimation of Aprepitant From Solid Dosage Form." American Journal Of Pharmacy And Health Research 10, no. 10 (2022): 20–32. https://doi.org/10.5281/zenodo.7270307.

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ABSTRACT The aim of the present work was to develop and validate a simple and efficient method for the analysis of Aprepitant in pharmaceutical dosage forms by reverse phase high-pressure liquid chromatography. A stainless steel column 75 mm long, 4.6 mm internal diameter filled with octasilyl silica chemically bonded with synthetic hybrid silica gel particles of 3.5 mm diameter was used for elution. The retention time of Aprepitant was 4.05 min. The method showed a good linearity in the concentration range of 0.02478 &ndash; 0.07434 mg/mL with a correlation coefficient of 0.9999. The validati
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MAHESHWARI, SUDHANSHU. "CURRENT CONTROLLED PRECISION RECTIFIER CIRCUITS." Journal of Circuits, Systems and Computers 16, no. 01 (2007): 129–38. http://dx.doi.org/10.1142/s0218126607003496.

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A novel full-wave precision rectifier employing a single current controlled conveyor (CCCII) with three outputs, two complementary MOS transistors, and a resistor is proposed. The circuit enjoys high input impedance, current controlled output, good zero-crossing performance, and linearity. Another current controlled precision rectifier with no external resistor is also derived from the proposed circuit. RSPICE simulations using real device parameters are included to verify the proposed circuits.
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Ieggli, Carine Viana Silva, Simone Gonçalves Cardoso, and Luziane Potrich Belle. "Validation of UV Spectrophotometric and Nonaqueous Titration Methods for the Determination of Carvedilol in Pharmaceutical Formulations." Journal of AOAC INTERNATIONAL 88, no. 5 (2005): 1299–303. http://dx.doi.org/10.1093/jaoac/88.5.1299.

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Abstract Ultraviolet (UV) spectrophotometric and nonaqueous volumetric methods are described for the determination of carvedilol in pharmaceutical formulations. Linearity, precision, and accuracy were evaluated according to the validation guidelines of the International Conference on Harmonizationand the United States Pharmacopeia for both methods. The UV spectrophotometric procedure was performed in ethanol at 244 nm. Good linearity was obtained between 2 and 7 μg/mL with a correlation coefficient of 0.9999. The intra- and interday precision values were &amp;lt;2% for all samples analyzed. Th
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Yu, A. Long, and Jin Qiao Dai. "A Method to Compensate Thermocouple Sensor Non-Linearity Based on Lagurre Orthogonal Polynomial Basis Functions Neural Network." Advanced Materials Research 834-836 (October 2013): 896–99. http://dx.doi.org/10.4028/www.scientific.net/amr.834-836.896.

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This paper presents a new method to compensate thermocouple sensor non-linearity based on laguerre orthogonal polynomial basis functions neural network. The mathematical model is established based on laguerre artificial neural network for non-linearity compensation. The principle and training algorithms of laguerre orthogonal polynomial basis functions neural network are introduced. The results show that non-linearity compensation method has the advantages of high precision, good real time and strong robustness, etc. The maximum non-linearity error is 0.17%.
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Rama, Annamalai, Induja Govindan, Srinivas Hebbar, Abhishek Chaturvedi, Usha Rani, and Anup Naha. "Advancing posaconazole quantification analysis with a new reverse-phase HPLC method in its bulk and marketed dosage form." F1000Research 12 (June 27, 2023): 468. http://dx.doi.org/10.12688/f1000research.132841.2.

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Introduction: Posaconazole is a widely used antifungal drug, and its accurate quantification is essential for quality control and assessment of its pharmaceutical products. This study aimed to develop and validate a reverse-phase high-performance liquid chromatography (HPLC) analytical method for quantifying Posaconazole in bulk and dosage form. Methods: The HPLC method was developed and validated based on International Conference on Harmonisation (ICH) guidelines. The developed method was then applied to quantify Posaconazole in a marketed tablet formulation. The method's specificity, lineari
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Dissertations / Theses on the topic "Linearity and Precision"

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Pipes, Latisha C. "Detection of Illicit Drug Use in Blood: A Validation Study of Solid Phase Extraction Coupled with Liquid Chromatography and Tandem Mass Spectrometry." Bowling Green State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1587613608312474.

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Cardoso, Adilson Silva. "Design and characterization of BiCMOS mixed-signal circuits and devices for extreme environment applications." Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/53099.

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State-of-the-art SiGe BiCMOS technologies leverage the maturity of deep-submicron silicon CMOS processing with bandgap-engineered SiGe HBTs in a single platform that is suitable for a wide variety of high performance and highly-integrated applications (e.g., system-on-chip (SOC), system-in-package (SiP)). Due to their bandgap-engineered base, SiGe HBTs are also naturally suited for cryogenic electronics and have the potential to replace the costly de facto technologies of choice (e.g., Gallium-Arsenide (GaAs) and Indium-Phosphide (InP)) in many cryogenic applications such as radio astronomy. T
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Dogantimur, Erkan, and Daniel Johnsson. "Analysis of Accuracy for Engine and Gearbox Sensors." Thesis, Uppsala universitet, Institutionen för teknikvetenskaper, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-388346.

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This thesis provides a standardized method to measure accuracy for engine and gearbox sensors. Accuracy is defined by ISO 5725, which states that trueness and precision need to be known to provide a metric for accuracy. However, obtaining and processing the data required for this is not straight forward. In this thesis, a method is presented that consists of two main parts: data acquisition and data analysis. The data acquisition part shows how to connect all of the equipment used and how to sample and store all the raw data from the sensors. The data analysis part shows how to process that ra
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Orsine, Eliane Maria de Almeida. "Determinação espectrofotométrica do cloridrato de ranitidina em medicamentos." Universidade de São Paulo, 1992. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-13102014-155903/.

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O cloridrato de ranitidina, um antagonista dos receptores H2 da histamina, foi determinado em comprimidos e injetáveis por espectrofotometria no ultravioleta, a 313nm, e por espectrofotometria no visível, a 615nm, utilizando o cloridrato da hidrazona da 3-metil-2-benzotiazolinona (MBTH) a 0,35% em HCl 0,M e cloreto férrico a 0,40% em HCl 0,1M, como reagentes de cor. Na espectrofotometria no ultravioleta a lei de Beer foi obedecida no intervalo de concentração de 5,0 a 18,0 &#181;g/mL. Quatro amostras comerciais foram analisadas. Os coeficientes de variação foram 0,36% e 0,71% para comprimidos,
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Chao, Yi-Hsiang, and 趙奕翔. "Linearity Parameter Estimation for A Precision Positioning Table." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/95243715680747462736.

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碩士<br>國立勤益技術學院<br>機械工程系<br>94<br>A precision positioning table is an electromechanical device、which combines the microcomputer、automatic control、and power machine. The table generally has the nonlinear properties、such as backlash、hysteresis、friction、and deformation due to heat effect、etc. It is important to consider those effects to a precision device. The purpose of this thesis is to measure the backlash by comparing the difference between the position command and the actual displacement. I also proposed a least square algorithm to estimate the parameters of the table. After that the differen
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Blackston, Matthew Allen. "PRECISION MEASUREMENTS OF DEUTERON PHOTODISINTEGRATION USING LINEARLY POLARIZED PHOTONS OF 14 AND 16 MEV." Diss., 2007. http://hdl.handle.net/10161/375.

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A precision measurement of the d(gamma ,n)p reaction was performed at the High Intensity gamma-ray Source (HIGS), which is located at the Duke Free Electron Laser Laboratory on the campus of Duke University. The gamma-ray beams were nearly 100% linearly polarized, allowing the angular distributions of both the analyzing power and unpolarized cross section to be measured at 14 and 16 MeV. The photons were incident on a heavy water target and the neutrons from the photodisintegration reaction were detected using the Blowfish detector array, which consists of 88 liquid scintillator detectors wi
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Book chapters on the topic "Linearity and Precision"

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Hou, Wenmei, and Günter Wilkening. "Investigation and Compensation of the Non-linearity of Heterodyne Interferometers." In Progress in Precision Engineering. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-84494-2_1.

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Lefaucheux, Engel, Joël Ouaknine, David Purser, and Mohammadamin Sharifi. "Model Checking Linear Dynamical Systems under Floating-point Rounding." In Tools and Algorithms for the Construction and Analysis of Systems. Springer Nature Switzerland, 2023. http://dx.doi.org/10.1007/978-3-031-30823-9_3.

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AbstractWe consider linear dynamical systems under floating-point rounding. In these systems, a matrix is repeatedly applied to a vector, but the numbers are rounded into floating-point representation after each step (i.e., stored as a fixed-precision mantissa and an exponent). The approach more faithfully models realistic implementations of linear loops, compared to the exact arbitrary-precision setting often employed in the study of linear dynamical systems.Our results are twofold: We show that for non-negative matrices there is a special structure to the sequence of vectors generated by the
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Ghosh, Pradip K. "Ion Traps In Atomic Physics." In Ion Traps. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780198539957.003.0006.

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Abstract In this chapter we present applications of ion traps to: (i) determination of the g-value of an electron from electron spin resonance experiments on a single electron, (ii) observation of quantum jumps in a single trapped ion, (iii) an experimental test of the quantum Zeno effect, (iv) a precision test of the linearity of quantum mechanics, (v) a range of studies on one-component microplasmas, (vi) optical spectroscopy of molecular ions, (vii) precision mass measurement of stable isotopes, (viii) precision mass measurement of radioactive isotopes, (ix) trapping and precision mass meas
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Kalyani, Potu, Buchi N. Nalluri, M. Chinna Eswaraiahc, and Tata Prasanna Kumarib. "Development of RP-HPLC-PDA Method Validation for the Simultaneous Estimation of Zidovudine, Lamivudine, and Nevirapine in Bulk and Dosage Forms and in Dissolution Samples." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00316.

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The purpose of this research is to design a rapid, efficient, and cost-effective RP-HPLC-PDA for the simultaneous determination of Nevirapine (NVP), Lamivudine (LMV), and Zidovudine (ZDV) in bulk, dosage forms, and dissolving samples. The maintained chromatographic conditions were an Inertsil ODS3 column (150×4.6mm,5µm) with 15mM Ammonium acetate: Methanol (55:45 v/v) as a mobile phase, injected in isocratic mode at flow-rate 1mL/min, eluents were measured at 270nm. LMV, ZDV, and NVP were eluted at 2.24, 3.88, and 8.15 minutes, respectively, under these LC conditions. At concentrations ranging
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He, Xiaoling, Yan Ma, Jiali Lu, Mei Long, Xing Deng, and Nian Zhang. "Determination of Five Isothiazolinone Preservatives in Liquid Detergents by High Performance Liquid Chromatography." In Advances in Transdisciplinary Engineering. IOS Press, 2022. http://dx.doi.org/10.3233/atde220364.

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In this study, an associate analytical approach supported by high performance liquid chromatography (HPLC) was developed to analyze five isothiazolinones in liquid detergents in the meanwhile. The isothiazolinones were extracted from liquid detergents by ultrasound with methanol as the extraction solvent and analyzed by HPLC. The gradient elution procedure uses acetonitrile-water as the mobile phase. The isothiazolinones were effectively separated by Agilent ZORBAX SB-C18 column (4.6 mm × 250 mm, 5 µm), and detected by diode array detector. The maximum absorption detection wavelengths of MIT,
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Rosales, Cristian, and Johnbrynner García. "A Novel Method for Titanium Dioxide Quantification in Cosmetic Products via Borate Fusion by Flame Atomic Absorption Spectroscopy." In Cosmetic Products and Industry - New Advances and Applications [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.110899.

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A new method for extraction of titanium dioxide (TiO2) from cosmetic matrices using borate salts for its quantification by flame atomic absorption spectroscopy (FAAS) was developed and validated. Following International Commission for Harmonization (ICH) and the United States Pharmacopeial Convention (USP) guidelines, the parameters of the method considered in this study were specificity, linearity, sensitivity, precision, and accuracy. In addition, critical factors of the method were assessed using a Youden–Steiner model. The method was able to differentiate the titanium signal from matrix an
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Godela, Ramreddy, Yagnambhatla Rajendra, Kranthi Kumar Pola, Dr Beda Durgaprasad, and Rani Dumpala. "IMPLEMENTATION OF GREEN SOLVENT SYSTEM FOR THE ANALYSIS OF ADAPALENE IN BULK AND TOPICAL GEL FORMULATION BY RP-HPLC." In Futuristic Trends in Pharmacy & Nursing Volume 2 Book 25. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2023. http://dx.doi.org/10.58532/v2bs25p2ch3.

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A simple and rapid stabilityindicating, RP-HPLC method was ascertained to determine adapalene in bulk and gel formulation. Separation was achieved on enable C18 column (150 x 4.6mm; 5μm) under the isocratic mode of elution by using mobile system mixture of green solvents tetrahydrofuran and methanol (30:70 V/V). The flow rate was maintained at 1.0 ml/min with runtime 10min. UV detection was done at 360 nm. The method was found to be linear for series concentration ranges from 20-100µg/ml. The limit of detection and quantification were found to be 3.27and 0.025µg/ml. Results of precision and ac
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Gopal, N. Madana, L. Siva Sanker Reddy, and R. Nageswara Rao. "METHOD DEVELOPMENT AND VALIDATION OF CILNIDIPINE IN TABLET DOSAGE FORM BY USING ULTRA VIOLET SPECTROPHOTOMETRY." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 11. Iterative International Publisher, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bgpn11p2ch5.

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A simple, quick, and accurate UV Spectroscopic method was developed to quantify celecoxib in API and tablet formulations. Celecoxib was used to treat rheumatoid arthritis and osteoarthritis. The proposed procedure was developed using acetonitrile and distilled water as the solvents in a 50:50 volume-to-volume ratio, and it was optimized using a Shimadzu UV-1800 ENG240V at a maximum wavelength of 240 nm with an absorbance of 0.558. The sensitivity, robustness, accuracy, and precision of the improved technique Degradation studies were also conducted and determined to be within the constraints. T
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Şenel, Selvi. "Change of Good." In Advances in Media, Entertainment, and the Arts. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-4778-6.ch003.

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In the postmodern era, concepts, notions, even ideologies that used to be concrete lost their precision. On the contrary to the clear point of view of modernism with linearity, postmodernism is circular and holistic. Thus, concepts like good and evil must not be seen as a total contrast. With the holistic approach of postmodernism, there can be evil in good and good in evil. In the popular fantasy texts that have been made especially in the last decade, this change easily can be seen in the characters. In this part, change of the good and the evil concepts in the fantasy genre will be examined
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Kasangaki, Wilberforce. "Method Validation and Verification." In Analytical Methods for Drug Development. THINKPLUS PHARMA PUBLICATIONS, 2025. https://doi.org/10.69613/28x3yy16.

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Method validation establishes analytical procedure reliability through systematic performance evaluation. ICH Q2(R1) guidelines provide validation frameworks adaptable across development phases from early research through commercialization. Risk-based approaches align validation effort with method purpose and product criticality. Validation parameters include specificity testing against potential interferents, linearity across concentration ranges, accuracy through recovery studies, precision at repeatability and intermediate levels, detection and quantitation limit determination, and robustne
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Conference papers on the topic "Linearity and Precision"

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Janásek, Vojtěch, Nikolai Beev, Boštjan Voljč, and Rado Lapuh. "Quadrature Bridge for Capacitor Non-linearity Measurement." In 2024 Conference on Precision Electromagnetic Measurements (CPEM). IEEE, 2024. http://dx.doi.org/10.1109/cpem61406.2024.10646122.

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Thomas, Jeremy N., Nathan E. Flowers-Jacobs, Anna E. Fox, Alain Rüfenacht, and Paul D. Dresselhaus. "Measuring VHF Detector Linearity using a Quantum-Based Source." In 2024 Conference on Precision Electromagnetic Measurements (CPEM). IEEE, 2024. http://dx.doi.org/10.1109/cpem61406.2024.10646166.

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Mejia, Jesus Medina, Alain Rüfenacht, Raegan Johnson-Wilke, et al. "Digitizer Linearity Measurement with a Josephson Arbitrary Waveform Synthesizer." In 2024 Conference on Precision Electromagnetic Measurements (CPEM). IEEE, 2024. http://dx.doi.org/10.1109/cpem61406.2024.10646120.

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Zhukova, Lena, Roger Artigas, and Guillem Carles. "Computational correction of scanner non-linearity in 3D microscopy." In Imaging Systems and Applications. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/isa.2024.if1d.2.

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Optical profilometers use axial scanning to measure object heights, and non-linear movement of the scanner yields measurement errors. We show a computational method to correct for non-linearity errors, thereby increasing measurement precision without added components.
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Pan, Yang, Ji Geng, Liren Zhou, Lei Lai, Yucheng Zhu, and Haiming Shao. "Research on the Linearity Test for the AC High Voltage Divider up to 1000 kV using a Stray Capacitance Divider." In 2024 Conference on Precision Electromagnetic Measurements (CPEM). IEEE, 2024. http://dx.doi.org/10.1109/cpem61406.2024.10646043.

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Bruce, Nicholas, and Thushara Kanchana Gunaratne. "Evaluating Low-Precision Floating-Point Formats for Next-Generation Radio Telescope Correlators and Beamformers: A Quantitative Analysis of Linearity and Dynamic Range." In Radio Frequency Interference Conference. Sissa Medialab, 2025. https://doi.org/10.22323/1.471.0024.

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Minowa, Isao, and Hiroyuki Tominaga. "Resistor's Linearity Testing." In 2004 Conference on Precision Electromagnetic Measurements. IEEE, 2004. http://dx.doi.org/10.1109/cpem.2004.305612.

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Kawakami, T., A. Widarta, and K. Komiyama. "A Consideration of Linearity in Heterodyne Detection." In 2004 Conference on Precision electromagnetic Digest. IEEE, 2004. http://dx.doi.org/10.1109/cpem.2004.305430.

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Carter, Nathan. "Achieving higher linearity in precision standard products." In 2017 IEEE Custom Integrated Circuits Conference (CICC). IEEE, 2017. http://dx.doi.org/10.1109/cicc.2017.7993715.

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Cassiago, Cristina, Roberto Cerri, Giuseppe Paglia, and Andrea Sosso. "Application of DMM Linearity to dc Volt Traceability." In 2004 Conference on Precision Electromagnetic Measurements. IEEE, 2004. http://dx.doi.org/10.1109/cpem.2004.305518.

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Reports on the topic "Linearity and Precision"

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Chutimaworapan, Suchada, Chaiyo Chaichantippayuth, and Areerat Laopaksa. Formulation of pharmaceutical products of Garcinia mangostana Linn. extracts. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.32.

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Part I: The purpose of the investigation was to develop the extraction process that was simple, practical and giving high yield. The maceration of dried powder of Garcinia mangostana fruit husk with ethyl acetate gave yellow crystalline powder of mangostin. The yield was calculated as 7.47%. The identification of the Garcinia mangostanahusk extract was carried out by thin-layer chromatography (TLC) and differential scanning calorimetry. The TLC of mangostin was done by using the alumina sheet and ethyl acetate: hexane (3:1) as mobile phase. The Rf value as compared with standard mangostin was
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Boisclair, Yves R., Alan W. Bell, and Avi Shamay. Regulation and Action of Leptin in Pregnant and Lactating Dairy Cows. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7586465.bard.

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The original project had four specific objectives: (1) To complete the development of a radioimmunoassay for bovine leptin; (2) To characterize the leptin system in lactating dairy cows during the transition from pregnancy to lactation; (3) To identify endocrine factors regulating the production of leptin by bovine adipose tissue; (4) To study the actions of leptin on bovine adipose and mammary tissues in vitro. However, BARD funded only the development of the bovine leptin RIA (Objective 1) for a single year. This report describes our work in completing this objective. Leptin, a protein hormo
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