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1

Yuan, Di, Vangelis Angelakis, Lei Chen, Eleftherios Karipidis, and Erik G. Larsson. "On Optimal Link Activation with Interference Cancelation in Wireless Networking." Linköpings universitet, Kommunikations- och transportsystem, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-81933.

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A fundamental aspect in performance engineering of wireless networks is optimizing the set of links that can be concurrently activated to meet given signal-to-interference-and-noise ratio (SINR) thresholds. The solution of this combinatorial problem is the key element in scheduling and cross-layer resource management. In this paper, we assume multiuser decoding receivers, which can cancel strongly interfering signals. As a result, in contrast to classical spatial reuse, links being close to each other are more likely to be active concurrently. Our focus is to gauge the gain of successive inter
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Cobb, Christina. "A Link Between Gut Microbes & Depression: Microbial Activation of the Human Kynurenine Pathway." Scholarship @ Claremont, 2018. http://scholarship.claremont.edu/cmc_theses/1799.

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Our gut microbiota is involved in human development, nutrition, and the pathogenesis of gut disorders, but has more recently been implicated as a possible mechanism in the pathophysiology of several brain disorders, including disorders of mood and affect, such as depression. Researchers have referred to this dynamic, bidirectional signaling pathway between the gut and the brain as the “gut-brain axis.” However, most research on this axis has been limited to rodent studies, and there has been little insight into the mechanism behind it. I propose that the kynurenine pathway, where tryptophan is
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3

Geng, Qifeng. "Time-efficient Computation with Near-optimal Solutions for Maximum Link Activation in Wireless Communication Systems." Thesis, Linköpings universitet, Kommunikations- och transportsystem, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-74571.

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In a generic wireless network where the activation of a transmission link is subject to its signal-to-noise-and-interference ratio (SINR) constraint, one of the most fundamental and yet challenging problem is to find the maximum number of simultaneous transmissions. In this thesis, we consider and study in detail the problem of maximum link activation in wireless networks based on the SINR model. Integer Linear Programming has been used as the main tool in this thesis for the design of algorithms. Fast algorithms have been proposed for the delivery of near-optimal results time-efficiently. Wit
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Dunn, Timothy Alan. "The link between neuronal activity and activation of the cAMP/PKA cascade in developing retinal ganglion cells." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC IP addresses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p3311360.

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Thesis (Ph. D.)--University of California, San Diego, 2008.<br>Title from first page of PDF file (viewed July 30, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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5

Brandstetter, Carolina [Verfasser]. "NLRP3 inflammasome activation by photooxidative damage provides a novel link between hallmark pathogenic features of age-dependent macular degeneration / Carolina Brandstetter." Bonn : Universitäts- und Landesbibliothek Bonn, 2016. http://d-nb.info/1124540350/34.

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6

Ntinas, Petros. "Function and activation of human adipose tissue : the role of genes in the link between physical activity and brown adipose-like phenotype." Thesis, University of Wolverhampton, 2017. http://hdl.handle.net/2436/620509.

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Background: Excess white adipose tissue (WAT) in humans is considered as a harmful health index. However, increased brown adipose tissue (BAT) and brown-like adipose tissue activity are associated with increased resting energy expenditure (REE) that may help to control body weight. Exercise may enhance browning formation of WAT and reduce WAT that may lead to health improvements. Aims: a) to examine the effects of physical activity on the link between peroxisome proliferator-activated receptor gamma co-activator 1-alpha (PGC-1α) and fibronectin type III domaincontaining protein 5 (FNDC5) genes
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Chung, Charlotte Yuk-Yan. "Tight Junctions - The Link Between HIV-Associated Intestinal Barrier Dysfunction and Loss of Immune Homeostasis." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1417822947.

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8

Roß, Annegret [Verfasser], and Paul [Akademischer Betreuer] Schulze-Lefert. "From perception to execution: Elucidation of signaling components that link initial MTI activation to local and systemic immunity in Arabidopsis / Annegret Roß. Gutachter: Paul Schulze-Lefert." Köln : Universitäts- und Stadtbibliothek Köln, 2012. http://d-nb.info/1046175750/34.

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9

Singatulina, Anastasiya. "The link between PARP1-mediated signaling and RNA-binding protein FUS in response to DNA damage PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLE042.

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La stabilité du génome est contrôlée par une machinerie complexe qui répare les dommages causés à l'ADN, le principal responsable du cancer et des maladies associées au vieillissement. En effet, Les cellules humaines sont exposées à différentes sources de stress oxydatif qui entraînent des dommages de l'ADN, notamment les cassures simple brin et les cassures double brin. Les sources de cassures de l’ADN peuvent être exogènes (lumière ultraviolette, pollution, rayonnements ionisants) ou endogènes (métabolisme cellulaire et inflammation). Après un stress génotoxique, les cellules de mammifères d
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10

Yang, Wenjing. "Maximisation d'influence dans les réseaux sociaux." Electronic Thesis or Diss., Aix-Marseille, 2019. http://theses.univ-amu.fr.lama.univ-amu.fr/191129_YANG_852tol142jmlj781pehwkj336i_TH.pdf.

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Récemment, un grand nombre de sites de réseaux sociaux sont apparus pour relier des personnes et des groupes. Les réseaux sociaux sont des bons outils pour obtenir des informations et communiquer des idées. La propagation de l’influence se produit lorsque les opinions ou les comportements d’un individu changent en conséquence des interactions avec les autres. Le problème de la maximisation de l’influence vise à identifier un sous-ensemble d’adopteurs initiaux dans un réseau social afin de maximiser la propagation de l’influence. Deux modèles progressifs sont principalement utilisés. Le modèle
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Komori, Junji. "Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma." Kyoto University, 2008. http://hdl.handle.net/2433/135857.

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12

Cho, Chin-wen C. "The role of germ-line immunoglobulins in autoimmunity and B cell activation." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/31640.

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The human antibody response to the AD-2S1 epitope of glycoprotein B (gB) of human cytomegalovirus (HCMV) is dominated by a family of closely related somatically mutated antibodies that are all derived from the same V H and V K germline genes. Our laboratory has previously reconstructed the putative germ-line-based ancestor of a somatically hypermutated antibody (8F9) against the AD-2S1 and characterized and compared the binding of the germline- based ancestral immunoglobulin and 8F9 (Igs) to the AD-2SI epitope. IgG1 versions of these antibodies bound to AD-2S1 by ELISA and glycoprotein B (gB)
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Edwards, Heather Gray. "Protection from oxidative stress in the cardiac H9C2-cell line by the transcription factor NRF2." Auburn, Ala., 2007. http://repo.lib.auburn.edu/07M%20Dissertations/GRAY-EDWARDS_HEATHER_53.pdf.

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14

Buffington, Adam G. "Links Between Depressive Symptoms and Reactive and Effortful Temperament Mediated by Behavioral Activation." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1335626338.

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15

Lin, Che-Hung [Verfasser], and Bernd [Akademischer Betreuer] Plietker. "Iron-catalyzed carbon-carbon bond activation / Che-Hung Lin ; Betreuer: Bernd Plietker." Stuttgart : Universitätsbibliothek der Universität Stuttgart, 2018. http://d-nb.info/120618387X/34.

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Chang, Annisa. "Effects of dopamine D¦2 receptor activation on prolactin release in a rat pituitary cell line." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0002/MQ28185.pdf.

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Ciesiolka, Malgorzata. "Studies of tax-mediated activation of BLV expression in silently infected ovine tumor B cell line." Doctoral thesis, Universite Libre de Bruxelles, 1998. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/212024.

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18

Teruya, Hideko. "Deciding to Look: Revisiting the Link between Lexical Activations and Eye Movements in the Visual World Paradigm in Japanese." Thesis, University of Oregon, 2019. http://hdl.handle.net/1794/24212.

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All current theories of spoken word recognition (e.g., Allopenna et al., 1998; McClelland & Elman, 1986; Norris, 1994) suggest that any part of a target word triggers activation of candidate words. Visual world paradigm studies have relied on the linking hypothesis that the probability of looking at the referent of a word directly tracks the word’s level of activation (e.g., Allopenna et al., 1998). However, how much information is needed to trigger a saccade to a visual representation of the word’s referent? To address this question, the present study manipulated the number and location of
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19

Rosenbaum, David [Verfasser], and Andreas [Akademischer Betreuer] Fallgatter. "Aberrant brain activation and coupling in Depression – Links between Psychopathology and Neurophysiology / David Rosenbaum ; Betreuer: Andreas Fallgatter." Tübingen : Universitätsbibliothek Tübingen, 2019. http://d-nb.info/1177790637/34.

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Sousa, Daniela Alexandra Costeira de. "Stimulation of a pDC cell line with self-DNA immune complexes." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22095.

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Mestrado em Biomedicina Molecular<br>Plasmacytoid dendritic cells (pDCs) are a subset of Dendritic Cells that when stimulated can produce pro-inflammatory mediators and type I IFNs. These cells play an important role in autoimmune disease such as systemic lupus erythematosus, as they can become activated by immune complexes formed with self-DNA, which trigger a type I IFN response through the TLR-9 signaling pathway. Here, we optimized activation of CAL-1 cells, a human pDC cell line, with immunocomplexes of self-nuclear or mitochondrial DNA with the antimicrobial peptide LL37. It was f
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Pourghahramani, Parviz. "Effects of grinding variables on structural changes and energy conversion during mechanical activation using line profile analysis (LPA) /." Luleå : Luleå tekniska universitet/Chemical Engineering and Geosciences/Mineral Processing, 2006. http://epubl.ltu.se/1402-1757/2006/19/index.html.

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22

Janes, Mandy Elaine. "Mechanisms of adrenocorticotropin-induced activation of erk 1/2 map kinase in the human H295R adrenal cell line." Thesis, Queen Mary, University of London, 2008. http://qmro.qmul.ac.uk/xmlui/handle/123456789/580.

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The role of ACTH in stimulating or inhibiting growth of adrenal cells has been a subject of some controversy. Reports that ACTH may stimulate Erk/MAP kinase in Y1 cells have suggested a role for cAMP in this process. In attempting to extend this work the ACTH responses in the human H295R cell line have been studied. This cell line makes only a very modest cAMP response to ACTH, yet the Erk1/2 response is highly reproducible and immediate, but not prolonged. It is minimally reduced by the protein kinase A inhibitor, H89, but unaffected by PKC and calcium inhibitors. Inhibition of EGF receptor o
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23

Athanassiou-Papaefthymiou, Maria G. "Functional activation of the p53 tumor suppressor in non-tumorigenic variants of the HeLa cervical carcinoma cell line." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/39376.

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24

Lin, Lin [Verfasser], Johannes A. [Akademischer Betreuer] Lercher, and Klaus [Akademischer Betreuer] Köhler. "Activation and Transformation of n-Alkanes and n-Alkene in Zeolites / Lin Lin. Gutachter: Johannes A. Lercher ; Klaus Köhler. Betreuer: Johannes A. Lercher." München : Universitätsbibliothek der TU München, 2012. http://d-nb.info/1031515380/34.

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Lin, Lin [Verfasser], Johannes [Akademischer Betreuer] Lercher, and Klaus [Akademischer Betreuer] Köhler. "Activation and Transformation of n-Alkanes and n-Alkene in Zeolites / Lin Lin. Gutachter: Johannes A. Lercher ; Klaus Köhler. Betreuer: Johannes A. Lercher." München : Universitätsbibliothek der TU München, 2012. http://d-nb.info/1031515380/34.

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26

Justement, Louis Barth. "Alteration in the expression of cyclic AMP dependent protein kinase isozymes associated with activation of a macrophage cell line /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487263399024575.

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27

Thorén, Katarina H. "Activation Policy in Action : A Street-Level Study of Social Assistance in the Swedish Welfare State." Doctoral thesis, Växjö universitet, Institutionen för vårdvetenskap och socialt arbete, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:vxu:diva-2474.

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Work-related activation policies are currently developing in most western welfare states. Sweden is no exception and activation policies were introduced in the 1990s in many municipal social services organizations in Sweden. The Swedish form of activation policies requires social assistance recipients to participate in mandatory activation program in return for financial support. This dissertation investigates the street-level implementation practices of activation policies within the context of the Swedish welfare state. The purpose of the study is to examine how street-level workers in the m
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Hishita, Terutoshi. "Caspase-3 activation by Iysosomal enzymes in cytochrome c-independent apoptosis in a myelodysplastic syndrome(MDS)-derived cell line P39." Kyoto University, 2001. http://hdl.handle.net/2433/150164.

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Sarrazin, Sébastien. "Fiabilisation et test des processeurs dans un contexte embarqué." Thesis, Paris, ENST, 2015. http://www.theses.fr/2015ENST0015/document.

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La réduction des marges temporelles dans les circuits synchrones est une manière d'améliorer leur performance.En cas de vieillissement, de fluctuations de la tension d'alimentation ou de la température du milieu de mission, des réductions sévères des marges temporelles peuvent néanmoins avoir un impact négatif sur la fiabilité des circuits. La réduction des marges temporelles sans dégradation de la fiabilité peut être réalisée à l'aide des informations d'un contrôle en ligne de ces marges. Cette thèse porte sur l'étude du suivi en ligne des marges temporelles des circuits intégrés synchrones.
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Aguilera, Rojas Matias Ignacio [Verfasser]. "Cellular crosstalk between canine fibroblasts and a mast cell tumour cell line and its significance in fibroblast activation / Matias Ignacio Aguilera Rojas." Berlin : Freie Universität Berlin, 2020. http://d-nb.info/1218530553/34.

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Rodrigues, Neto Jo?o Firmino. "Perfil de mem?ria e ativa??o de linf?citos T na leishmaniose visceral." Universidade Federal do Rio Grande do Norte, 2010. http://repositorio.ufrn.br:8080/jspui/handle/123456789/12574.

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Made available in DSpace on 2014-12-17T14:03:36Z (GMT). No. of bitstreams: 1 JoaoFRN_DISSERT.pdf: 3516278 bytes, checksum: 9fe0338a2547517c2f45d91b7860116c (MD5) Previous issue date: 2010-12-03<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior<br>Visceral leishmaniasis (VL) in Brazil is a disease caused by Leishmania infantum chagasi (L.i.chagasi). The clinical evolution post-infection depends on the vertebrate host immune response, which is genetically mediated. This study aimed to evaluate the immune response of individuals living in endemic area for VL in the state of the Rio
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Hawley, Brett. "The Purification and Identification of Interactors to Elucidate Novel Connections in the HEK 293 Cell Line." Thèse, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/23536.

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The field of proteomics studies the structure and function of proteins in a large scale and high throughput manner. My work in the field of proteomics focuses on identifying interactions between proteins and discovering novel interactions. The identification of these interactions provides new information on metabolic and disease pathways and the working proteome of a cell. Cells are lysed and purified using antibody based affinity purification followed by digestion and identification using an HPLC coupled to a mass spectrometer. In my studies, I looked at the interaction networks of several AD
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Patte-Boucrel, Valérie. "Propriétés physicochimiques de pectines, gélification par réticulation chimique et application à la gélification de milieux de culture." Rouen, 1992. http://www.theses.fr/1992ROUES054.

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Ce travail est une contribution à l'étude de macromolécules pectiques. Il comprend trois parties: 1) Etude physico-chimique des interactions des ions sodium et calcium avec deux classes de pectines de lin. On montre que le pKa et les coefficients d'activités sont interprétables par le modèle de condensation dont on propose une extension théorique au cas des mélanges de polyélectrolytes; 2) Nous décrivons une nouvelle méthode de gélification des pectines par pontage chimique grâce à un carbodiimide hydrosoluble. L'influence des réactifs sur les caractéristiques des gels est étudiée; 3) Dans la
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34

Mozaffari-Jovin, Sina [Verfasser], Reinhard [Akademischer Betreuer] Lührmann, Reinhard [Akademischer Betreuer] Jahn, and Ralf [Akademischer Betreuer] Ficner. "Mechanism of regulation of spliceosome activation by Brr2 and Prp8 and links to retinal disease / Sina Mozaffari-Jovin. Gutachter: Reinhard Jahn ; Ralf Ficner. Betreuer: Reinhard Lührmann." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://d-nb.info/1044870877/34.

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Heim, Whitefield Karen Elizabeth. "Mechanism of RRR-[alpha]-tocopheryl succinate activation of latent TGF-[beta] and induction of cell growth inhibition in the human breast cancer cell line MDA-MB-435 /." Digital version accessible at:, 1999. http://wwwlib.umi.com/cr/utexas/main.

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Watanabe, Kenichiro. "Prevention of etoposide-induced apoptosis by Proteasome inhibitors in a human leukemic cell line but not in fresh acute leukemia blasts : A differential role of NF-κB activation". Kyoto University, 2000. http://hdl.handle.net/2433/151424.

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Lepers, Capucine. "Pollution atmosphérique de proximité et toxicité respiratoire : recherche in vitro des mécanismes d'action toxique induits par des aérosols atmosphériques particulaires (PM₂.₅) industriels, urbains et ruraux." Thesis, Littoral, 2013. http://www.theses.fr/2013DUNK0352/document.

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Les particules fines (PM₂.₅) présentes dans l'air extérieur peuvent être inhalées puis retenues au niveau pulmonaire, conduisant à l'apparition ou à l'aggravation de différentes pathologies cardio-respiratoires. La composition complexe des PM₂.₅ rend d'autant plus difficile l'étude de leurs mécanismes d'action. Cette thèse s'inscrit donc dans une démarche d'identification des processus impliqués dans un éventuel potentiel cancérigène des PM₂.₅, en lien avec leur composition chimique. Nous avons étudié la toxicité de six échantillons de PM₂.₅, collectés sous influence industrielle, urbaine ou r
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Logan, Marisa Kay. "Activation of signal transduction pathways by monocyte chemotactic proteins-1, -2, -3 and -4 in the THP-1 monocytic cell line : regulation of CCR2 signalling cascades by phosphatidylinositol-3-kinases." Thesis, University of Bath, 2002. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760816.

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39

Vondruš, Jiří. "Návrh a konstrukce modelu automatické galvanizační linky." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2008. http://www.nusl.cz/ntk/nusl-217635.

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This thesis deals with the design of automated system of electroplating. The first part is centered on designing the technological process for this electroplating and the setout of operating vats. It also deals with the project of mechanical construction, electrical system, with the computing procedure and the optimum choice of gear for galvanic line model. The work includes the design of a DC motor controller, the computing procedure and the construction of heating element for vats heater simulation. The last part of this thesis offers an insight to the control system and the assembled progra
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40

Borgie, Mireille. "Étude des particules fines et ultrafines en suspension dans l'air au Liban : caractérisation physicochimique et évaluation des effets toxicologiques sur des cellules pulmonaires humaines BEAS-2B." Thesis, Littoral, 2014. http://www.theses.fr/2014DUNK0366/document.

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Les principaux objectifs de cette étude, une des premières menée au Liban, étaient d’acquérir une meilleure connaissance des caractéristiques physico-chimiques des particules atmosphériques fines (PF ou PM₂.₅₋₀.₃) et ultrafines (PUF ou PM₀.₃), et d’évaluer in vitro, leur potentiel toxique sur des cellules épithéliales bronchiques humaines (BEAS-2B). L’échantillonnage de PF et de PUF a été mené au Liban à la fois sur un site urbain (Sin El-Fil, du 18 mai au 2 sept. 2011) et un site rural (Beije, du 5 sept. au 28 oct. 2011). Les PF et les PUF ont fait l’objet d’une caractérisation physico-chimiq
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Praz, Françoise. "Effets de l'activation du systeme du complement sur differentes populations lymphocytaires." Paris 6, 1987. http://www.theses.fr/1987PA066589.

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Grimsley, Philip George Medical Sciences Faculty of Medicine UNSW. "Receptor mediated catabolism of plasminogen activators." Awarded By:University of New South Wales. Medical Sciences, 2009. http://handle.unsw.edu.au/1959.4/44489.

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Humans have two plasminogen activators (PAs), tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA), which generate plasmin to breakdown fibrin and other barriers to cell migration. Both PAs are used as pharmaceuticals but their efficacies are limited by their rapid clearance from the circulation, predominantly by parenchymal cells of the liver. At the commencement of the work presented here, the hepatic receptors responsible for mediating the catabolism of the PAs were little understood. tPA degradation by hepatic cell lines was known to depend on the forma
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CHOKRI, MOHAMED. "Controle de l'activation du macrophage murin in-vitro et in-vivo : effet antitumoral et action de differents immunostimulants." Université Louis Pasteur (Strasbourg) (1971-2008), 1989. http://www.theses.fr/1989STR13061.

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Mise au point d'une methode pour la proliferation de macrophages murins residents en presence de cellules nourricieres. Etablissement et caracterisation de differentes lignees cellulaires de macrophages. Utilisation de ces macrophages actives pour une immunotherapie de tumeurs solides chez la souris, comparaison avec des immunomodulateurs comme les interferons et le facteur de necrose tumorale
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Virion, Zoé. "Interaction de Neisseria meningitidis avec les cellules endothéliales humaines : rôle des glycosylations des récepteurs cellulaires eucaryotes Receptor recognition by meningococcal type IV pili relies on a specific triantennary N-­glycan Sialic acid‐mediated allosteric activation of β2-­adrenoceptors An ADAM-­10 dependent EPCR shedding links meningococcal interaction with endothelial cells to purpura fulminans". Thesis, Sorbonne Paris Cité, 2018. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=2296&f=12491.

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Neisseria meningitidis est une bactérie commensale du rhinopharynx portée de façon asymptomatique par 10 à 35% de la population. Pour une raison encore inconnue à ce jour, cette bactérie est capable de traverser la barrière épithéliale et ainsi proliférer dans la circulation sanguine de l’hôte, où elle est capable d’adhérer aux cellules endothéliales grâce aux pili de type IV. Sur ces cellules, le méningocoque interagit spécifiquement avec le récepteur d’adhésion CD147 et le récepteur β2-adrénergique qui active la signalisation sous la colonie bactérienne adhérente, favorisant l’ancrage de cel
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Han, Kilsoo. "Professionalitetens gränser : Socialsekreterares erfarenheter av unga vuxna klienter med komplexa behov inom socialtjänst–ekonomiskt bistånd." Thesis, Uppsala universitet, Centrum för socialt arbete - CESAR, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-422371.

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This study explores the experiences of the Swedish front-line social workers (socialsekreterare) in the municipal income support unit, Young Adults, monthly assessing the income support applications as well as daily processing the activation programs for young adult clients with mental ill-health combined with social-medicinal vulnerabilities, also referred to as young adults with complex needs. Furthermore, this study aims to illuminate the ever changing conditions of the Swedish welfare state and its underlying driving forces through the lens of the social workers. 9 Semi-structured distance
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46

Roda, Noguera Oriol. "Caracterització dels receptors de l'activador tissular del plasminogen (tPA) en càncer de pàncrees." Doctoral thesis, Universitat Pompeu Fabra, 2006. http://hdl.handle.net/10803/7100.

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El càncer de pàncrees és altament agressiu i representa la cinquena causa de mort al mon occidental. Anteriorment, en el nostre laboratori, vam identificar que el receptor tissular del plasminogen (tPA) hi està sobre-expressat i juga un paper important el la progressió tumoral. En la present tesi hem profunditzat en l'estudi del mecanisme molecular de tPA i seus receptors en aquest càncer. <br/>En primer lloc hem caracteritzat en detall la interacció de tPA amb Annexina A2 (principal receptor de tPA en endoteli i altament expressada en pàncrees) demostrant que les dades publicades sobre la seq
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Badour, Karen Elizabeth. "The Wiskott-Aldrich syndrome protein : forging a link between actin polymerization and T cell activation." 2005. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=232849&T=F.

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48

"Pattern recognition receptors and cytokine-mediated activation of human basophils: a novel link between innate immunity and allergic inflammation." 2013. http://library.cuhk.edu.hk/record=b5549787.

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過敏性疾病(如過敏性哮喘和過敏性皮炎)發病率在香港及世界均呈上升趨勢。過敏性哮喘是一種慢性反復發作的炎症疾病,而過敏性皮炎是一種慢性皮膚炎症。呼吸道細菌及金黃色葡萄球菌可分別加重過敏性哮喘病人氣道炎症及過敏性皮炎患者的炎症反應。人體對細菌的先天免疫反應主要通過模式識別受體(PRR)介導。NOD樣受體(NLR)和Toll樣受體(TLR)是兩種重要的PRR。 NLR 家族成員NOD2幾乎識別所有細菌中結構保守的胞壁醯二肽(MDP)。而LTR2識別範圍廣泛的病原相關分子模式,如革蘭氏陽性菌中的肽聚糖(PGN)和脂磷壁酸(LTA),以及人工合成的脂蛋白Pam3CSK4。<br>本研究包括:NOD2配體MDP,哮喘相關的腫瘤壞死因子家族成員LIGHT對共培養的人嗜鹼性粒細胞和人支氣管上皮細胞的活化作用;熱滅活的金黃色葡萄球菌(HKSA),MDP,TLR2配體PGN,LTA,以及Pam3CSK4對共培養的人嗜鹼性粒細胞和人皮膚成纖維細胞的活化作用;在體內NLR配體對卵清蛋白(OVA)致敏的哮喘小鼠的作用。<br>研究發現,在共培養體系中,MDP能顯著增強嗜鹼性粒細胞與支氣管上皮細胞表面粘附因子(細胞間粘附因子ICAM-1 及血管細胞粘附因子VCAM-1)的表達。同時,MDP能顯著促進共培養體系中炎症相關細胞因子IL-6,趨化因子CXCL8及抗菌肽β-防禦素2的釋放。在MDP刺激下,支氣管上皮細
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Lee, Kyeong-Hee [Verfasser]. "Cofilin : a novel link between T-cell activation and the rearrangement of the actin cytoskeleton / vorgelegt von Kyeong-Hee Lee." 2002. http://d-nb.info/968346197/34.

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Robertson, Natalie. "A cross-sectional cohort study of core stability muscle activation and endurance in elite male athletes and its link with mechanical lower back pain." Thesis, 2005. http://hdl.handle.net/10321/328.

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Thesis(M.Tech.: Chiropractic)- Dept. of Chiropractic, Durban Institute of Technology, 2005 xi, 62 leaves<br>To compare the relative activation and endurance of core stability muscles in 2 different populations i.e. elite athletes and non-athletes, and establish whether these findings correspond to episodes of mechanical lower back pain.
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