Relevant bibliographies by topics / Lipid backbone

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  2. Dissertations / Theses
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  5. Conference papers

Academic literature on the topic 'Lipid backbone'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Lipid backbone"

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Becker, Kevin W., Felix J. Elling, Marcos Y. Yoshinaga, Andrea Söllinger, Tim Urich, and Kai-Uwe Hinrichs. "Unusual Butane- and Pentanetriol-Based Tetraether Lipids in Methanomassiliicoccus luminyensis, a Representative of the Seventh Order of Methanogens." Applied and Environmental Microbiology 82, no. 15 (2016): 4505–16. http://dx.doi.org/10.1128/aem.00772-16.

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ABSTRACTA new clade of archaea has recently been proposed to constitute the seventh methanogenic order, theMethanomassiliicoccales, which is related to theThermoplasmatalesand the uncultivated archaeal clades deep-sea hydrothermal ventEuryarchaeotagroup 2 and marine group IIEuryarchaeotabut only distantly related to other methanogens. In this study, we investigated the membrane lipid composition ofMethanomassiliicoccus luminyensis, the sole cultured representative of this seventh order. The lipid inventory ofM. luminyensiscomprises a unique assemblage of novel lipids as well as lipids otherwis
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Zhu, Chun, Travis B. Meador, Wolf Dummann, and Kai-Uwe Hinrichs. "Identification of unusual butanetriol dialkyl glycerol tetraether and pentanetriol dialkyl glycerol tetraether lipids in marine sediments." Rapid Communications in Mass Spectrometry 28 (December 27, 2013): 332–38. https://doi.org/10.1002/rcm.6792.

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RATIONALE: Glycerol serves as the principal backbone moiety bound to various acyl/alkyl chains for membrane lipids of <em>Eukarya</em>, <em>Bacteria</em>, and <em>Archaea</em>. In this study, we report a suite of unusual tetraether lipids in which one of the two conventional glycerol backbones is substituted by butanetriol or pentanetriol. METHODS: Identification of these lipids was achieved via diagnostic fragments and their expected acetylation products using liquid chromatography/mass spectrometry (LC/MS), and their diagnostic ether cleavage products using gas chromatography/mass spectromet
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Kooijman, Laurens, Philipp Ansorge, Matthias Schuster, et al. "Backbone and methyl assignment of bacteriorhodopsin incorporated into nanodiscs." Journal of Biomolecular NMR 74, no. 1 (2019): 45–60. http://dx.doi.org/10.1007/s10858-019-00289-7.

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AbstractResonance assignments are challenging for membrane proteins due to the size of the lipid/detergent-protein complex and the presence of line-broadening from conformational exchange. As a consequence, many correlations are missing in the triple-resonance NMR experiments typically used for assignments. Herein, we present an approach in which correlations from these solution-state NMR experiments are supplemented by data from 13C unlabeling, single-amino acid type labeling, 4D NOESY data and proximity of moieties to lipids or water in combination with a structure of the protein. These addi
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Coffinet, Sarah, Travis B. Meador, Lukas Mühlena, et al. "Structural elucidation and environmental distributions of butanetriol and pentanetriol dialkyl glycerol tetraethers (BDGTs and PDGTs)." Biogeosciences 17, no. 2 (2020): 317–30. http://dx.doi.org/10.5194/bg-17-317-2020.

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Abstract. Butanetriol and pentanetriol dialkyl glycerol tetraethers (BDGTs and PDGTs) are membrane lipids, recently discovered in sedimentary environments and in the methanogenic archaeon Methanomassiliicoccus luminyensis. They possess an unusual structure, which challenges fundamental assumptions in lipid biochemistry. Indeed, they bear a butanetriol or a pentanetriol backbone instead of a glycerol at one end of their core structure. In this study, we unambiguously located the additional methyl group of the BDGT compound on the C3 carbon of the lipid backbone via high-field nuclear magnetic r
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van Kranenburg, Richard, Iris I. van Swam, Joey D. Marugg, Michiel Kleerebezem, and Willem M. de Vos. "Exopolysaccharide Biosynthesis in Lactococcus lactis NIZO B40: Functional Analysis of the Glycosyltransferase Genes Involved in Synthesis of the Polysaccharide Backbone." Journal of Bacteriology 181, no. 1 (1999): 338–40. http://dx.doi.org/10.1128/jb.181.1.338-340.1999.

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ABSTRACT We used homologous and heterologous expression of the glycosyltransferase genes of the Lactococcus lactis NIZO B40 eps gene cluster to determine the activity and substrate specificities of the encoded enzymes and established the order of assembly of the trisaccharide backbone of the exopolysaccharide repeating unit. EpsD links glucose-1-phosphate from UDP-glucose to a lipid carrier, EpsE and EpsF link glucose from UDP-glucose to lipid-linked glucose, and EpsG links galactose from UDP-galactose to lipid-linked cellobiose. Furthermore, EpsJ appeared to be involved in EPS biosynthesis as
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Choi, Dong Jin, and Zeeshan Ur Rehman. "Interfacial Behaviors of Transmembrane Peptides in Lipid Bilayer Studied by X-Ray and Neutron Reflectivity." Materials Science Forum 977 (February 2020): 184–89. http://dx.doi.org/10.4028/www.scientific.net/msf.977.184.

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Lipids and proteins can influence each other in so many different ways. Lipids may affect the structure of membrane proteins by influencing their backbone conformation, the tilt, rotation angles of their transmembrane (TM) segments, and the orientation of their side chains. The membrane-spanning parts in integral membrane proteins are predominantly hydrophobic, and most often helical. At the lipid-protein interface, the TM part of the protein and the hydrocarbon chains of the lipid molecules have to coexist to maintain the integrity of the membrane. Lipids are important components of lipid mem
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Ngo, An Thien, Pierre Karam, and Gonzalo Cosa. "Conjugated polyelectrolyte–lipid interactions: Opportunities in biosensing." Pure and Applied Chemistry 83, no. 1 (2010): 43–55. http://dx.doi.org/10.1351/pac-con-10-11-02.

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Fluorescent conjugated polyelectrolytes (CPEs) have attracted considerable interest over the past decade as novel materials for developing biosensing schemes and sensing devices for biomolecules. This interest stems from the exquisite polymer sensitivity to the presence of fluorescence quenchers, enabling amplified sensing of molecules of interest. Efficient energy transport along the polymer backbone is critical to their sensing capabilities. Considerable research efforts have thus gone into understanding and controlling energy transport along the polymer backbone. In particular, it has been
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Passos Gibson, Victor, Martin Fauquignon, Emmanuel Ibarboure, Jeanne Leblond Chain, and Jean-François Le Meins. "Switchable Lipid Provides pH-Sensitive Properties to Lipid and Hybrid Polymer/Lipid Membranes." Polymers 12, no. 3 (2020): 637. http://dx.doi.org/10.3390/polym12030637.

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Blending amphiphilic copolymers and lipids constitutes a novel approach to combine the advantages of polymersomes and liposomes into a new single hybrid membrane. Efforts have been made to design stimuli-responsive vesicles, in which the membrane’s dynamic is modulated by specific triggers. In this investigation, we proposed the design of pH-responsive hybrid vesicles formulated with poly(dimethylsiloxane)-block-poly(ethylene oxide) backbone (PDMS36-b-PEO23) and cationic switchable lipid (CSL). The latter undergoes a pH-triggered conformational change and induces membrane destabilization. Usin
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Crittenden, Christopher M., Carmen M. Herrera, Peggy E. Williams, et al. "Mapping phosphate modifications of substituted lipid Aviaa targeted MS3CID/UVPD strategy." Analyst 143, no. 13 (2018): 3091–99. http://dx.doi.org/10.1039/c8an00561c.

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Structural characterization of lipid A remains a challenge with respect to localizing modifications of the phosphate groups found on the reducing and non-reducing ends of the disaccharide backbone of lipid A.
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GUTIÉRREZ-GONZÁLEZ, Luis H., Christian LUDWIG, Carsten HOHOFF, et al. "Solution structure and backbone dynamics of human epidermal-type fatty acid-binding protein (E-FABP)." Biochemical Journal 364, no. 3 (2002): 725–37. http://dx.doi.org/10.1042/bj20020039.

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Human epidermal-type fatty acid-binding protein (E-FABP) belongs to a family of intracellular 14–15kDa lipid-binding proteins, whose functions have been associated with fatty acid signalling, cell growth, regulation and differentiation. As a contribution to understanding the structure—function relationship, we report in the present study features of its solution structure and backbone dynamics determined by NMR spectroscopy. Applying multi-dimensional high-resolution NMR techniques on unlabelled and 15N-enriched recombinant human E-FABP, the 1H and 15N resonance assignments were completed. On
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Dissertations / Theses on the topic "Lipid backbone"

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COGLIATI, CLELIA. "NMR study of chicken Liver Bile Acid Binding Protein: interaction and dynamics." Doctoral thesis, Università degli Studi di Verona, 2010. http://hdl.handle.net/11562/343942.

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Il principale obiettivo di questo lavoro di tesi è lo studio del ruolo giocato da un ponte disolfuro sulle proprietà di legame di una proteina citosolica, la Liver Bile Acid Binding Protein (L-BABP), nella quale è naturalmente presente. In particolare si vuole far luce sulle capacità della proteina di legare Acidi Biliari (BA) e sulle sue proprietà funzionali. Gli acidi biliari circolano tra il fegato e l’intestino attraverso un meccanismo definito “circolazione enteroepatica”, il quale è fortemente regolato dagli stessi acidi biliari. Gli acidi biliari sono infatti in grado di influenzare l’e
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Books on the topic "Lipid backbone"

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Reiner, Željko, Olov Wiklund, and John Betteridge. Lipids. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656653.003.0015.

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Dyslipidaemia, particularly elevated low-density lipoprotein (LDL) cholesterol, is one of the most important risk factors for cardiovascular disease (CVD). Low concentrations of high-density lipoprotein (HDL) cholesterol are independently associated with high CVD risk, while moderately elevated triglycerides are considered to be a marker of increased CVD risk. The presence of dyslipidaemias secondary to other conditions must be excluded before beginning treatment. All patients with familial hypercholesterolaemia are at high risk and should be treated by lipid-lowering therapy. Lifestyle change
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Book chapters on the topic "Lipid backbone"

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Cornell, Bruce A., Frances Separovic, and Ross Smith. "Side Chain and Backbone Conformation of Gramicidin a in Lipid Bilayer Membranes." In The Jerusalem Symposia on Quantum Chemistry and Biochemistry. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-3075-9_19.

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Lücke, Christian, David Fushman, Christian Ludwig, James A. Hamilton, James C. Sacchettini, and Heinz Rüterjans. "A comparative study of the backbone dynamics of two closely related lipid binding proteins: Bovine heart fatty acid binding protein and porcine ileal lipid binding protein." In Lipid Binding Proteins within Molecular and Cellular Biochemistry. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4929-1_13.

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Nosheen, Shaista, Tahira Naz, Yusuf Nazir, and Yuanda Song. "Sphingolipid." In Fungal Lipid Biochemistry. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815123012123010011.

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Sphingolipids are a class of lipids containing the backbone of long-chain amino-alcohol bases in their structure, which are synthesized in the endoplasmic reticulum. Modification of this base gives rise to a variety of such lipids ranging from simple to complex sphingolipids that play a significant structural and functional role in membrane biology as well as regulate various cellular processes. Sphingosine, dihydrosphingosine and phytosphingosine are nature's most frequently occurring bases. Ceramides are the simplest sphingolipids after the backbone. These fatty acids are amide-linked deriva
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McDonald, Kallum, Stacy D. Singer, and Guanqun Chen. "Recent Advances in the Biosynthesis and Metabolic Engineering of Storage Lipids and Proteins in Seeds." In Functional Materials from Lipids and Proteins. Royal Society of Chemistry, 2024. http://dx.doi.org/10.1039/9781839167980-00021.

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During plant seed maturation, a key developmental step is the storage of biomolecules that remain within the embryo throughout dormancy and provide the necessary metabolites to support seedling growth. Seed storage lipids and proteins are among the most valuable materials for food, industrial, and other applications. Triacylglycerol (TAG) is the major storage lipid in most terrestrial plants and is an energy-dense molecule. TAGs are composed of one glycerol backbone esterified to three fatty acid (FA) tails and are highly abundant in the seeds of oleaginous plants. Seed storage proteins (SSPs)
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"Acetate–Malonate Pathway: Fatty Acids and Polyketides." In Chemical Diversity of Plant Specialized Metabolites. Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671472-00035.

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The acetate–malonate pathway produces fatty acids and polyketides. Fatty acids, consisting of an aliphatic carbon chain with a carboxylic acid group at one end and a methyl group at the other end, are biosynthesized in the chloroplasts in the green tissues and in the plastids of non-photosynthetic tissues. Biosynthesis of fatty acid starts from acetyl-CoA. Two enzyme systems, namely acetyl-CoA carboxylase and fatty acid synthase are required for fatty acid biosynthesis. Lipoic acid is biosynthesized in mitochondria. Triacylglycerols, waxes, lipid polyesters (cutin, suberin), sphingolipids or o
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Stymne, Sten, and A. Keith stobart. "Triacylglycerol biosynthesis." In Seed Storage Compounds. Oxford University PressOxford, 1990. http://dx.doi.org/10.1093/oso/9780198577683.003.0006.

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Abstract Plant triacylglycerols, commonly known as vegetable oils and fats, have many applications in the food and chemical industry and are a most important commodity in world trade. In the triacylglycerol molecule, one fatty acid residue is esterified to each of the three hydroxy groups of the glycerol backbone. The quality of the oil, and hence its end use, is determined by the fatty acid composition and, to some extent, the positional acyl distribution. All commercial annual oil crops have seed oils largely composed of the five major fatty acids, palmitic (16:0), stearic (18:0), oleic (18:
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Scarlata, Suzanne F. "The Effects of Increased Viscosity on the Function of Integral Membrane Proteins." In High Pressure Effects in Molecular Biophysics and Enzymology. Oxford University Press, 1996. http://dx.doi.org/10.1093/oso/9780195097221.003.0024.

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For many years the idea that the activity of integral membrane proteins is regulated by the fluidity of the lipid matrix was popular and appeared to be quite rational. However, as information about the effect of viscosity on the function of different membrane proteins became available, the correlation between the two became increasingly unclear. The purpose of this article is to readdress this issue in light of our recent pressure and temperature studies. This chapter is divided into seven parts: (1) the effect of viscosity on enzyme activity; (2) the effect of viscosity on the local motions o
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Griffiths, H. R., and J. Lunec. "Investigating the effects of oxygen free radicals on carbohydrates in biological systems." In Free Radicals. Oxford University PressOxford, 1996. http://dx.doi.org/10.1093/oso/9780199635603.003.0013.

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Abstract Carbohydrates are a large family of related molecules defined as polyhydroxy aldehydes or ketones, and their derivatives. They perform a diverse range of biological functions, both in their own right, in the derivation of energy for cellular maintenance and survival, or as conjugates to larger macromolecules such as proteins or lipids. In addition, the 5-C sugar deoxyribose is an integral component of the DNA backbone and its oxygenated form is critical to the integrity of RNA.
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Conference papers on the topic "Lipid backbone"

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Gutiérrez-González, Luis H. "Backbone Dynamics Of Intracellular Lipid Binding Proteins." In MATERIALS SCIENCE AND APPLIED PHYSICS: 2nd Mexican Meeting on Mathematical and Experimental Physics. AIP, 2005. http://dx.doi.org/10.1063/1.1928162.

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Wu, Haizhou, Bita Forghani, Ingrid Undeland, and Mehdi Abdollahi. "Lipid oxidation in sorted herring (Clupea harengus) filleting co-products and its relationship to composition." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/uelt7673.

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In industrial fish filleting, around 30–70 % of the total weight of the fish end up as side streams (often called by- or co-products), such as the head, backbone, caudal fin, skin, and intestines. Currently, these fractions are dedicated to low value uses as fodder meals or mink feed, even if they contain significant amounts of protein, long chain (LC) n-3 polyunsaturated fatty acids (PUFA), and other nutrients such as vitamins and minerals. However, most fish processors mix their side streams, not least when it comes to small pelagic species like herring. This practice limits use of the side
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Ullah, Aman, Huiqi Wang, and Rehan Pradhan. "Lipid Derived Block Copolymers as Amphiphilic Nanocarriers for Targeted Delivery." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/bfgi9101.

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Amphiphilic thermoresponsive block copolymers and ABA type PEG-Lipid conjugated macromolecules have been synthesized using microwave-assisted reversible addition-fragmentation chain transfer (RAFT) polymerization and the copper-catalyzed azide-alkyne cycloaddition, commonly termed “click chemistry”, respectively. Characterization of the block copolymers and conjugates has been carried out with the help of 1H-NMR, FTIR and GPC. These copolymers and conjugates were evaluated for the encapsulation and release of drugs. Carbamazepine, an anticonvulsant drug with poor water solubility was selected
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Wu, Haizhou, Mehdi Abdollahi, and Ingrid Undeland. "Lipid Oxidation in Innovative Protein Enriched Products from Cod- salmon and Herring Backbones During Ice and Frozen Storage." In Virtual 2021 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2021. http://dx.doi.org/10.21748/am21.337.

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