Log in

Relevant bibliographies by topics / Lipid Based Drug Delivery System / Journal articles

To see the other types of publications on this topic, follow the link: Lipid Based Drug Delivery System.

Journal articles on the topic 'Lipid Based Drug Delivery System'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Lipid Based Drug Delivery System.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Jaswinder, Singh *. "LIPID NANOPARTICULATE DRUG DELIVERY SYSTEMS." Journal of Pharma Research 8, no. 8 (2019): 557–63. https://doi.org/10.5281/zenodo.3374087.

Full text

Abstract:

<strong><em>ABSTRACT</em></strong> <strong><em>C</em></strong><em>olloidal particles of size range between 10 and 1000 nm are known as nanoparticles. Over the last few years, lipid based drug delivery systems such as solid lipid nanoparticle (SLN) and nanostructured lipid carrier (NLC) and lipid drug conjugate (LDC) have become the most promising drug delivery systems. Each preparation of the lipid based nanoparticles has advantages and disadvantages with respect to specific characteristics. The SLN is an excellent drug delivery system and has extensive prospects in the pharmaceutical field. N

APA, Harvard, Vancouver, ISO, and other styles

2

Shrestha, Hina, Rajni Bala, and Sandeep Arora. "Lipid-Based Drug Delivery Systems." Journal of Pharmaceutics 2014 (May 19, 2014): 1–10. http://dx.doi.org/10.1155/2014/801820.

Full text

Abstract:

The principle objective of formulation of lipid-based drugs is to enhance their bioavailability. The use of lipids in drug delivery is no more a new trend now but is still the promising concept. Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address challenges like the solubility and bioavailability of poorly water-soluble drugs. Lipid-based formulations can be tailored to meet a wide range of product requirements dictated by disease indication, route of administration, cost consideration, product stability, toxicity, and efficacy. These formulations

APA, Harvard, Vancouver, ISO, and other styles

3

Mounika, Nandru* Madhu Gudipati S.S. Manikiran and Ramarao Nadendla. "LIPID BASED DRUG DELIVERY SYSTEM – A REVIEW." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 03 (2019): 5834–44. https://doi.org/10.5281/zenodo.2598606.

Full text

Abstract:

<em>Lipid-based drug delivery systems (LBDDS) have gained significant attention in recent times, owing to their ability to overcome the challenges limiting the oral delivery of poorly water-soluble drugs. Despite the successful commercialization of several LBDDS products over the years, a large discrepancy exists between the number of poorly water-soluble drugs displaying optimal in-vivo performances and the application of LBDDS to mitigate their various delivery challenges. The formation of drugs carried out with the principle objective of enhancing their bioavailability. Poorly water-soluble

APA, Harvard, Vancouver, ISO, and other styles

4

Jain, Shikha, Vikas Jain, and S. C. Mahajan. "Lipid Based Vesicular Drug Delivery Systems." Advances in Pharmaceutics 2014 (September 2, 2014): 1–12. http://dx.doi.org/10.1155/2014/574673.

Full text

Abstract:

Vesicular drug delivery system can be defined as highly ordered assemblies consisting of one or more concentric bilayers formed as a result of self-assembling of amphiphilic building blocks in presence of water. Vesicular drug delivery systems are particularly important for targeted delivery of drugs because of their ability to localize the activity of drug at the site or organ of action thereby lowering its concentration at the other sites in body. Vesicular drug delivery system sustains drug action at a predetermined rate, relatively constant (zero order kinetics), efficient drug level in th

APA, Harvard, Vancouver, ISO, and other styles

5

Kotta, Sabna, Navneet Sharma, Prateek Raturi, Mohd Aleem, and Rakesh Kumar Sharma. "Exploring Novel Strategies for Lipid-Based Drug Delivery." Journal of Nanotoxicology and Nanomedicine 3, no. 1 (2018): 1–22. http://dx.doi.org/10.4018/jnn.2018010101.

Full text

Abstract:

Currently, the concept of lipid-based drug delivery systems has gained much interest because of their capability to deliver drugs which dissolve sparingly in water or insoluble in nature. Several methods of lipid-based drug delivery exist, and each method has its own advantages as well as limitations. The primary objective of the formulation development is to improve the bioavailability of the drug. The nano-sized lipid-based drug delivery systems have enough potential to do so. This article addresses the various barriers to the transportation of drugs through certain routes and also the commo

APA, Harvard, Vancouver, ISO, and other styles

6

Pranali, Jadhav Pranali Hatwar Gajanan Sanap. "Review On Lipid Based Carrier As A Drug Delivery System." International Journal in Pharmaceutical Sciences 1, no. 12 (2023): 179–91. https://doi.org/10.5281/zenodo.10352354.

Full text

Abstract:

Lipid nanocarriers represent an alternative to polymeric nanoparticles, liposomes, and emulsions. Nanostructured Lipid Nanocarriers (NLCs), considered as the second-generation lipid carriers, aim to address the limitations of Solid Lipid Nanoparticles. They are employed across diverse therapeutic approaches and were initially designed for delivering lipophilic drugs, but their effectiveness with hydrophilic drugs is now well-established. The biocompatibility of lipids underpins their emergence as a promising avenue for drug delivery, exhibiting superior traits compared to other lipid formulati

APA, Harvard, Vancouver, ISO, and other styles

7

Meghana, Raykar, and Shinde Ramesh. "SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM: A LIPID BASED DRUG DELIVERY SYSTEM." INTERNATIONAL JOURNAL OF CURRENT RESEARCH AND INNOVATIONS IN PHARMA SCIENCES 1, no. 1 (2022): 16–21. https://doi.org/10.5281/zenodo.8017592.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Chime, Salome A., Paul A. Akpa, and Anthony A. Attama. "The Utility of Lipids as Nanocarriers and Suitable Vehicle in Pharmaceutical Drug Delivery." Current Nanomaterials 4, no. 3 (2019): 160–75. http://dx.doi.org/10.2174/2405461504666191016091827.

Full text

Abstract:

Lipid based excipients have gained popularity recently in the formulation of drugs in order to improve their pharmacokinetic profiles. For drugs belonging to the Biopharmaceutics Classification System (BCS) class II and IV, lipid excipients play vital roles in improving their pharmacokinetics properties. Various nanocarriers viz: Solid lipid nanoparticles, nanostructured lipid carriers, selfnanoemulsifying drug delivery systems (SNEDDS), nanoliposomes and liquid crystal nanoparticles have been employed as delivery systems for such drugs with evident successes. Lipid-based nanotechnology have b

APA, Harvard, Vancouver, ISO, and other styles

9

Nida, Parveen *. "SOLID LIPID NANOPARTICLE: A NOVEL APPROACH IN DRUG DELIVERY SYSTEM." Journal of Pharma Research 8, no. 5 (2019): 341–45. https://doi.org/10.5281/zenodo.3236717.

Full text

Abstract:

<strong><em>ABSTRACT</em></strong> <strong><em>T</em></strong><em>he solid lipid nanoparticles possess a lipid core matrix in a nanometer range, stabilized by a surfactant layer. These are based on biocompatible lipids and provide sustained effect on the formulation either by diffusion or dissolution. SLN have several advantages over other colloidal carriers, such as the possibility of controlling drug release, long term stability, drug targeting, and good drug loading of drugs may it be lipophilic or hydrophilic, free from biotoxicity due to the use of physiological lipids. The use of solid l

APA, Harvard, Vancouver, ISO, and other styles

10

Ankita, S. Dhopate, A. Katekar Vinayak, and T. Hemke Atul. "Exploring lipids: A comprehensive review on their utilization in the formulation of liposomes, phytosomes, and ethosomes for advanced drug delivery systems"." GSC Biological and Pharmaceutical Sciences 28, no. 2 (2024): 099–115. https://doi.org/10.5281/zenodo.14676333.

Full text

Abstract:

This comprehensive review explores the diverse applications of lipids in the formulation of advanced drug delivery systems, specifically focusing on liposomes, phytosomes, and ethosomes. Lipids, crucial components in these formulations, play a pivotal role in enhancing drug solubility, stability, and bioavailability. The review systematically examines the latest advancements in lipid-based delivery systems, shedding light on their unique characteristics and applications. In the realm of liposomes, the study delves into various lipid compositions, highlighting their influence on liposomal struc

APA, Harvard, Vancouver, ISO, and other styles

11

Zarif, Leila, John R. Graybill, David Perlin, and Raphael J. Mannino. "Cochleates: New Lipid-Based Drug Delivery System." Journal of Liposome Research 10, no. 4 (2000): 523–38. http://dx.doi.org/10.3109/08982100009031116.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Mehanna, Mohammed, Adel Motawaa, and Magda Samaha. "Pharmaceutical particulate carriers: Lipid - based carriers." National Journal of Physiology, Pharmacy and Pharmacology 2, no. 1 (2012): 10. https://doi.org/10.5455/njppp.2012.v2.i1.2.

Full text

Abstract:

Drug delivery research areas is continuously broaden and modified as a results of the realization of many factors (such as poor drug solubility and/or absorption, rapid metabolism, high fluctuation in the drug plasma level and variability) which play major role in adversely affecting in vivo results, in conventional drug delivery system. Lipids are one of the basic building blocks of biological membranes. Nanoscale-based delivery strategies are beginning to make a significant impact on global pharmaceutical planning and marketing. Among the approaches for exploiting nanotechnology developments

APA, Harvard, Vancouver, ISO, and other styles

13

Thakare, Priya, Vrushali Mogal, Jaydeep Dusane, and Sanjay Kshirsagar. "A review on self-emulsified drug delivery system." Pharmaceutical and Biological Evaluations 3, no. 2 (2016): 140–53. https://doi.org/10.5281/zenodo.51056.

Full text

Abstract:

Improving oral bioavailability of low poorly water soluble drugs using self-emulsifying drug delivery systems (SEDDS) possess significant potential. Oral bioavailability of hydrophobic drugs can be improved using SEDDS, and appears most promising. Their dispersion in gastro intestinal (GI) fluid after administration forms micro or nano emulsified drug which gets easily absorbed through lymphatic pathways bypassing the hepatic first pass metabolism. Parameters like surfactant concentration, oil to surfactant ratio, polarity of emulsion, droplet size and charge on droplet plays a critical role i

APA, Harvard, Vancouver, ISO, and other styles

14

Patil, Deepak, Seema Pattewar, Sarvesh Palival, Gargi Patil, and Swapnil Sharma. "Nanostructured lipid carriers: A platform to lipophilic drug for oral bioavailability enhancement." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 758–64. http://dx.doi.org/10.22270/jddt.v9i3-s.2750.

Full text

Abstract:

Lipid based drug delivery system such as Solid lipid nanoparticle (SLN) and Nanostructured lipid carriers (NLC) are among the most promising drug delivery system used in many industries such as food, pharmaceuticals and cosmetics industries. Over the last few years, new constituents of lipids have developed and investigated for enhancement of bioavailability. The present manuscript is an attempt on solving the concerned uncertainty with efficacious peroral administration of hydrophobic drugs through fabricating new lipid formulations, NLC. NLC, the second-generation lipid carrier is usually co

APA, Harvard, Vancouver, ISO, and other styles

15

Mittal, Ayush Nandkishore, Awate Shyam Suryakant, Sanjay R. Arote, and Varun Satish Pawar. "Nanostructured Lipid Carriers As A Drug Delivery System." Journal of Neonatal Surgery 14, no. 7 (2025): 904–11. https://doi.org/10.63682/jns.v14i7.6456.

Full text

Abstract:

Nanostructured Lipid Carriers (Nlcs) Are Drug Delivery System Comprising A Mixture Of Solid And Liquid Lipids As A Core Matrix. Furthermore, Nlcs Are Second-Generation Lipid Nanoparticles That Have An Unstructured Matrix With High Drug Loading Capacity, Which Are Suitable For Drug Delivery System. Due To These Unique Characteristics, Several Studies Have Investigated Nlcs As Alternate Carriers For The Dermal Delivery Of Pharmaceuticals, Particularly Natural Active Ingredients. Among The Associated Benefits Discovered Include Biocompatible Ingredients, Drug Release Modification, And Adhesion To

APA, Harvard, Vancouver, ISO, and other styles

16

S. Patil, Snehal, Akshay R. Yadav, Rohan R. Vakhariya, Akash Kere, Sadik Sayyad, and Shweta Patil. "“Design, Evaluation and Optimization of Novel Topical Drug Delivery System of Antifungal Agent”." Cuestiones de Fisioterapia 54, no. 3 (2025): 1174–86. https://doi.org/10.48047/abpsd215.

Full text

Abstract:

The core of nanostructured lipid carriers (NLCs), which are colloidal drug delivery systems at the nanoscale, is a lipid mixture made up of both liquid and solid lipids. In contrast to polymeric or metallic nanoparticles, this lipid-based nanosystem is presented as a safe, non-toxic, and biocompatible nano-drug delivery method. Optimizing and characterizing a transdermal drug delivery system loaded with antifungal medications using Nanostructured Lipid Carriers (NLC) is the objective of this work. By extending the drug release via the NLC transdermal gel, this study aims to optimize NLCs and i

APA, Harvard, Vancouver, ISO, and other styles

17

M. Dadure, Kanhaiya, and Animeshchandra G. M. Haldar. "Cryptosomes: A Novel Promising Drug Delivery System." International Journal of Medical & Pharmaceutical Sciences 07, no. 01 (2017): 01–05. http://dx.doi.org/10.31782/ijmps.2017.7101.

Full text

Abstract:

Vesicular drug delivery systems might be a solution to the problem of limited bioavailability and rapid clearance of medications from the body. The four kinds of lipid-based drug delivery techniques include solid-lipid particle system, emulsion-based system, solid lipid tablet, and vesicular system. Cryptosomes are a novel vesicular drug delivery system that may solve some of the shortcomings of classic drug delivery methods, such as high stability, enhanced bioavailability, longer release, and decreased elimination of fast metabolizable drugs, among others. Cryptosome is derived from the Gree

APA, Harvard, Vancouver, ISO, and other styles

18

Rehman, Mubashar, Nayab Tahir, Muhammad Farhan Sohail, et al. "Lipid-Based Nanoformulations for Drug Delivery: An Ongoing Perspective." Pharmaceutics 16, no. 11 (2024): 1376. http://dx.doi.org/10.3390/pharmaceutics16111376.

Full text

Abstract:

Oils and lipids help make water-insoluble drugs soluble by dispersing them in an aqueous medium with the help of a surfactant and enabling their absorption across the gut barrier. The emergence of microemulsions (thermodynamically stable), nanoemulsions (kinetically stable), and self-emulsifying drug delivery systems added unique characteristics that make them suitable for prolonged storage and controlled release. In the 1990s, solid-phase lipids were introduced to reduce drug leakage from nanoparticles and prolong drug release. Manipulating the structure of emulsions and solid lipid nanoparti

APA, Harvard, Vancouver, ISO, and other styles

19

Zhao, Yan-Qi, Li-Jun Li, Er-Fen Zhou, et al. "Lipid-Based Nanocarrier Systems for Drug Delivery: Advances and Applications." Pharmaceutical Fronts 04, no. 02 (2022): e43-e60. http://dx.doi.org/10.1055/s-0042-1751036.

Full text

Abstract:

Lipid-based nanocarriers have been extensively investigated for drug delivery due to their advantages including biodegradability, biocompatibility, nontoxicity, and nonimmunogenicity. However, the shortcomings of traditional lipid-based nanocarriers such as insufficient targeting, capture by the reticuloendothelial system, and fast elimination limit the efficiency of drug delivery and therapeutic efficacy. Therefore, a series of multifunctional lipid-based nanocarriers have been developed to enhance the accumulation of drugs in the lesion site, aiming for improved diagnosis and treatment of va

APA, Harvard, Vancouver, ISO, and other styles

20

Gorain, Bapi. "Multivesicular Liposome: A Lipid-based Drug Delivery System for Efficient Drug Delivery." Current Pharmaceutical Design 27, no. 43 (2021): 4404–15. http://dx.doi.org/10.2174/18734286mte3cntq0z.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Mani, Sugapradha, and Venkatesan Kotteeswaran. "Advancement of lipid-polymer hybrid nanoparticles in targeted drug delivery in cancer therapy." Research Journal of Biotechnology 18, no. 3 (2023): 116–24. http://dx.doi.org/10.25303/1803rjbt1160124.

Full text

Abstract:

A lipid-polymer hybrid nanoparticle (LPHNP) is a drug delivery vehicle specifically designed for incorporating hydrophobic lipids and hydrophilic polymers into a single system. These hybrid nanoparticles are synthesized from a variety of methods including one-step or a two –step approach based on the desired structure of lipids and polymers construct themselves into an integrated delivery agent through self assembly. This hybrid system offers more advantages than their equivalent individual nanoparticle such as the ability to tune the particle size, loading wide range of drugs into them, exten

APA, Harvard, Vancouver, ISO, and other styles

22

Dewangan, Akash, Lavakesh Kumar Omray, Naveen Gupta, Dharmendra Singh Rajput, and Dusmanta Kumar Pradhan. "Formulation And Evaluation Of Thymoquinone Loaded Nlc By Emulsion Evaporation Method." Journal of Neonatal Surgery 14, no. 9S (2025): 772–80. https://doi.org/10.52783/jns.v14.2794.

Full text

Abstract:

Nanoparticles based controlled drug release can also reduce the side effects of drugs. Benefits of nanoparticle drug delivery systems include minimised irritant reactions and improved penetration within the body due to their small size, allowing for intravenous and other delivery routes. Oral administration is the most convenient route among various routes of drug delivery as it offers high patient compliance. However, the poor aqueous solubility and poor enzymatic/metabolic stability of drugs are major limitations in successful oral drug delivery. There are several approaches to improve probl

APA, Harvard, Vancouver, ISO, and other styles

23

Semalty, Ajay, Mona Semalty, Balwant Singh Rawat, Devendra Singh, and MSM Rawat. "Pharmacosomes: the lipid-based new drug delivery system." Expert Opinion on Drug Delivery 6, no. 6 (2009): 599–612. http://dx.doi.org/10.1517/17425240902967607.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Kallem Sharat Venkat Reddy. "Clinical implications of novel polymer and lipid based drug delivery systems." International Journal of Research in Hospital and Clinical Pharmacy 2, no. 3 (2020): 60–65. http://dx.doi.org/10.33974/ijrhcp.v2i3.232.

Full text

Abstract:

The use of lipids in drug delivery is not a new trend, some of the lipid dosage forms have been in use for a long time such as suppositories, creams, and emulsions. However, there has been much advancement in the designs of lipid carriers over the past decade. In the same way from the past two decades, new approaches in biodegradable and bio-reducible polymers have paved a way for many recent drug delivery systems. Applications of these novel drug delivery formulations have been promising clinically. However, each system has its pros and cons in various factors depending upon their use and int

APA, Harvard, Vancouver, ISO, and other styles

25

Rethi, Lekshmi, Chinmaya Mutalik, Dito Anurogo, et al. "Lipid-Based Nanomaterials for Drug Delivery Systems in Breast Cancer Therapy." Nanomaterials 12, no. 17 (2022): 2948. http://dx.doi.org/10.3390/nano12172948.

Full text

Abstract:

Globally, breast cancer is one of the most prevalent diseases, inducing critical intimidation to human health. Lipid-based nanomaterials have been successfully demonstrated as drug carriers for breast cancer treatment. To date, the development of a better drug delivery system based on lipid nanomaterials is still urgent to make the treatment and diagnosis easily accessible to breast cancer patients. In a drug delivery system, lipid nanomaterials have revealed distinctive features, including high biocompatibility and efficient drug delivery. Specifically, a targeted drug delivery system based o

APA, Harvard, Vancouver, ISO, and other styles

26

Rajput, Amrapali V. Dr. Shaikh Nasheer S.* Anantwal Akshat B. Joshi Maharudra R. Limaye Akhilesh S. "Emulsome: A Revolutionary Advancement in Pharmaceutical Delivery." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 715–25. https://doi.org/10.5281/zenodo.15341507.

Full text

Abstract:

Emulsome are emerging as a promising lipid-based nanocarriers system designed to address the challenges of delivering hydrophobic drugs. By combining the structural advantages of liposomes and emulsions, emulsome feature a solid lipid core enveloped by a phospholipid bilayer. This unique architecture enhances drug solubility, protects bioactive compounds from degradation, and enables controlled and targeted drug release. This review provides a comprehensive analysis of emulsome composition, preparation techniques, and physicochemical properties. It also explores their versatile applications in

APA, Harvard, Vancouver, ISO, and other styles

27

Quach, Hung, Tuong-Vi Le, Thanh-Thuy Nguyen, Phuong Nguyen, Cuu Khoa Nguyen, and Le Hang Dang. "Nano-Lipids Based on Ginger Oil and Lecithin as a Potential Drug Delivery System." Pharmaceutics 14, no. 8 (2022): 1654. http://dx.doi.org/10.3390/pharmaceutics14081654.

Full text

Abstract:

Lipid nanoparticles based on lecithin are an interesting part of drug delivery systems. However, the stability of lecithin nano-lipids is problematic due to the degradation of lecithin, causing a decrease in pH. In this study, the modification of the conventional nano-lipid-based soybean lecithin was demonstrated. Ginger-oil-derived Zingiber officinale was used along with lecithin, cholesterol and span 80 to fabricate nano-lipids (GL nano-lipids) using a thin-film method. TEM and a confocal microscope were used to elucidate GL nano-lipids’ liposome-like morphology. The average size of the resu

APA, Harvard, Vancouver, ISO, and other styles

28

Abhishek Yadav, Mohd Amaan, Adarsh Dubey, and Dheeraj Kushwaha. "Pharmacosomes: In Targeted Drug Delivery System." Asian Journal of Pharmaceutical Research and Development 12, no. 5 (2024): 41–45. http://dx.doi.org/10.22270/ajprd.v12i5.1476.

Full text

Abstract:

Pharmacosomes are a cutting-edge method of medication delivery based on a lipid transport system. A novel approach to drug delivery called "drug targeting" seeks to deliver the medication to the intended site of action or absorption while preventing any other non-target site from being exposed to it. Drug targeting is a practical delivery method that allows medicinal agents to be delivered to a particular location without endangering other organs. Pharmacosomes are colloidal drug dispersions that are hexagonally assembled into micelles, vesicles, or nanometric- size micelles that are covalentl

APA, Harvard, Vancouver, ISO, and other styles

29

U., Aiswarya M., Keerthana Raju, Revathy B. Menon, Lakshmi V. S., and Sreeja C. Nair. "CRYPTOSOMES: A REVOLUTIONARY BREAKTHROUGH IN NOVEL DRUG DELIVERY." International Journal of Applied Pharmaceutics 11, no. 1 (2019): 7. http://dx.doi.org/10.22159/ijap.2019v11i1.29077.

Full text

Abstract:

The vesicular drug delivery systems are promising approaches to overthrown the problems of drugs having lesser bioavailability and rapid elimination from the body. The four type of lipid based drug delivery systems are: solid-lipid particulate system, emulsion based system, solid lipid tablet and vesicular system. Cryptosomes, a novel emerging vesicular drug delivery system which can overcome the disadvantages associated with conventional drug delivery systems like high stability, increased bioavailability, sustained release, decreased elimination of rapidly metabolizable drugs etc. The word C

APA, Harvard, Vancouver, ISO, and other styles

30

Berillo, Dmitriy, Adilkhan Yeskendir, Zharylkasyn Zharkinbekov, Kamila Raziyeva, and Arman Saparov. "Peptide-Based Drug Delivery Systems." Medicina 57, no. 11 (2021): 1209. http://dx.doi.org/10.3390/medicina57111209.

Full text

Abstract:

Peptide-based drug delivery systems have many advantages when compared to synthetic systems in that they have better biocompatibility, biochemical and biophysical properties, lack of toxicity, controlled molecular weight via solid phase synthesis and purification. Lysosomes, solid lipid nanoparticles, dendrimers, polymeric micelles can be applied by intravenous administration, however they are of artificial nature and thus may induce side effects and possess lack of ability to penetrate the blood-brain barrier. An analysis of nontoxic drug delivery systems and an establishment of prospective t

APA, Harvard, Vancouver, ISO, and other styles

31

Efendy Goon, Danial, Siti Hamimah Sheikh Abdul Kadir, Normala Ab Latip, Sharaniza Ab. Rahim, and Musalmah Mazlan. "Palm Oil in Lipid-Based Formulations and Drug Delivery Systems." Biomolecules 9, no. 2 (2019): 64. http://dx.doi.org/10.3390/biom9020064.

Full text

Abstract:

Palm oil is natural oil packed with important compounds and fatty acids ready to be exploited in lipid-based formulations and drug delivery. Palm oil and palm kernel oil contain long-chain and medium-chain triglycerides, respectively, including phytonutrients such as tocotrienol, tocopherol and carotenes. The exploitation of these compounds in a lipid-based formulation would be able to address hydrophobicity, lipophilicity, poor bioavailability and low water-solubility of many current drugs. The utilisation of palm oil as part of the drug delivery system seemed to improve the bioavailability a

APA, Harvard, Vancouver, ISO, and other styles

32

Matei, Andreea-Mariana, Constantin Caruntu, Mircea Tampa, et al. "Applications of Nanosized-Lipid-Based Drug Delivery Systems in Wound Care." Applied Sciences 11, no. 11 (2021): 4915. http://dx.doi.org/10.3390/app11114915.

Full text

Abstract:

Impaired wound healing is an encumbering public health issue that increases the demand for developing new therapies in order to minimize health costs and enhance treatment efficacy. Available conventional therapies are still unable to maximize their potential in penetrating the skin at the target site and accelerating the healing process. Nanotechnology exhibits an excellent opportunity to enrich currently available medical treatments, enhance standard care and manage wounds. It is a promising approach, able to address issues such as the permeability and bioavailability of drugs with reduced s

APA, Harvard, Vancouver, ISO, and other styles

33

Limongi, Tania, Francesca Susa, Monica Marini, et al. "Lipid-Based Nanovesicular Drug Delivery Systems." Nanomaterials 11, no. 12 (2021): 3391. http://dx.doi.org/10.3390/nano11123391.

Full text

Abstract:

In designing a new drug, considering the preferred route of administration, various requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a valuable drug profile as well as well-tolerated. Over the past 20 years, nanotechnologies have provided alternative and complementary solutions to those of an exclusively pharmaceutical chemical nature since scientists and clinicians invested in the optimization of materials and methods capable of regulating effective drug delivery at the nanometer scale. Among the many drug delivery carriers, lipid nano vesicular ones s

APA, Harvard, Vancouver, ISO, and other styles

34

Mohammad, Shoaib Shaikh Hamid, R. Hatwar Pooja, L. Bakal Ravindrakumar, and B. Kohale Nitin. "A comprehensive review on Liposomes: As a novel drug delivery system." GSC Biological and Pharmaceutical Sciences 27, no. 1 (2024): 199–210. https://doi.org/10.5281/zenodo.11974168.

Full text

Abstract:

Liposomes, as versatile lipid-based nanoparticles, have emerged as promising drug delivery systems in recent years. This comprehensive review aims to provide an in-depth analysis of the advancements, challenges, and potential applications of liposomes in drug delivery. The review covers various aspects of liposome-based drug delivery, including their structure, formulation methods, advantages, limitations, and recent breakthroughs in the field. Furthermore, we discuss the diverse range of drugs and therapeutic agents that can be encapsulated within liposomes, as well as their clinical applicat

APA, Harvard, Vancouver, ISO, and other styles

35

Agosti, Edoardo, Marco Zeppieri, Sara Antonietti, et al. "Navigating the Nose-to-Brain Route: A Systematic Review on Lipid-Based Nanocarriers for Central Nervous System Disorders." Pharmaceutics 16, no. 3 (2024): 329. http://dx.doi.org/10.3390/pharmaceutics16030329.

Full text

Abstract:

Background: The blood–brain barrier (BBB) regulates brain substance entry, posing challenges for treating brain diseases. Traditional methods face limitations, leading to the exploration of non-invasive intranasal drug delivery. This approach exploits the direct nose-to-brain connection, overcoming BBB restrictions. Intranasal delivery enhances drug bioavailability, reduces dosage, and minimizes systemic side effects. Notably, lipid nanoparticles, such as solid lipid nanoparticles and nanostructured lipid carriers, offer advantages like improved stability and controlled release. Their nanoscal

APA, Harvard, Vancouver, ISO, and other styles

36

Abhay, S. Jejurkar* Angad B. Newre Akash B. Ravate Abhishek S. Wakle Dr. Rajendra M. Kawade. "Niosomes: Pharmaceutical Novel Drug Delivery System." International Journal in Pharmaceutical Sciences 1, no. 11 (2023): 18–24. https://doi.org/10.5281/zenodo.10060583.

Full text

Abstract:

Niosome is an innovative drug delivery system designed to address the challenges associated with conventional drug administration methods. This system employs advanced nanotechnology to encapsulate pharmaceutical compounds within lipid-based nanovesicles, known as niosomes. Niosomes offer several advantages, including enhanced drug stability, controlled release, and improved bioavailability. This technology holds great promise for improving the efficacy and safety of various drugs, leading to better patient outcomes. This abstract provides a glimpse into the potential of neosomes as a groundbr

APA, Harvard, Vancouver, ISO, and other styles

37

Kumar Sahoo, Prabhat, Neha S.L, and Arzoo Pannu. "An Overview of Second Generation Nanoparticles− Nanostructure Lipid Carrier Drug Delivery System." International Journal of Pharmaceutical Sciences and Nanotechnology 13, no. 6 (2020): 5181–89. http://dx.doi.org/10.37285/ijpsn.2020.13.6.2.

Full text

Abstract:

Lipids are used as vehicles for the preparation of various formulations prescribed for administrations, including emulsions, ointments, suspension, tablets, and suppositories. The first parental nano-emulsion was discovered from the 1950s when it was added to the intravenous administration of lipid and lipid-soluble substances. Lipid-based drug delivery systems are important nowadays. Solid nanoparticles (SLN) and Nanostructured lipid carriers (NLC) are very proficient due to the ease of production process, scale-up capability, bio-compatibility, the biodegradability of formulation components

APA, Harvard, Vancouver, ISO, and other styles

38

Elavarasi E, Vanitha Sri T, Harinisri S, Farhatyassir M, Kavinragul A, and Srinivasan R. "Biodegradable Nanomaterials in Drug Delivery Systems." Journal of Pharma Insights and Research 3, no. 2 (2025): 073–81. https://doi.org/10.69613/0x0swg65.

Full text

Abstract:

Biodegradable nanoparticles have revolutionized drug delivery by enhancing therapeutic efficacy while minimizing environmental impact. These nanocarriers, composed of biocompatible polymers, lipids, proteins, and inorganic materials, enable targeted drug delivery and controlled release kinetics, reducing dosing frequency and improving patient compliance. Their natural degradation into non-toxic byproducts addresses long-term toxicity concerns and offers an environmentally conscious alternative to conventional delivery systems. Polymeric nanoparticles, particularly those based on chitosan, poly

APA, Harvard, Vancouver, ISO, and other styles

39

Limaye, Akhilesh Dr. Shaikh Nasheer* Humnabade Shital Anantwal Akshat Babhulkar Akshay Joshi Maharudra Rajput Amrapali. "Comprehensive Review on Nanostructured Lipid Carriers." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3423–31. https://doi.org/10.5281/zenodo.15474137.

Full text

Abstract:

Nanostructured lipid carriers (NLCs) represent a novel nanoparticulate drug delivery system composed of solid lipids, liquid lipids, emulsifying agents, and an aqueous phase. In recent years, NLCs have garnered considerable scientific and clinical interest due to their superior drug delivery capabilities, offering notable advantages over conventional dosage forms. Nanostructured lipid carriers (NLCs) are second generation lipid-based nanocarriers formulated using biocompatible solid lipids, liquid lipids, surfactants, and co-surfactants. These systems are capable of encapsulating a wide range

APA, Harvard, Vancouver, ISO, and other styles

40

Santhosh, Kumar C.* Ganesh N. S. J. Adlin Jino Nesalin Vineeth Chandy. "Emulsomes: An Advancing Nanotechnology for Targeted Drug Delivery Systems and Therapeutics." International Journal of Pharmaceutical Sciences 3, no. 2 (2025): 1357–68. https://doi.org/10.5281/zenodo.14881136.

Full text

Abstract:

Lipid-based drug delivery systems have been widely employed over the past few decades for efficient drug delivery. These systems offer several benefits, including protection of drugs from the biological environment, thereby improving their therapeutic efficacy. Various types of lipid-based drug delivery systems have been developed, such as solid lipid nanoparticles, liposomes, emulsions, emulsomes, pharmacosomes, lipospheres, Nano emulsions, niosomes, and transferosomes. Among these, emulsomes have garnered significant attention due to their unique properties, which overcome many limitations a

APA, Harvard, Vancouver, ISO, and other styles

41

NARENDER, BOGGULA, BAKSHI VASUDHA, and PEDDAPALLI HIMABINDU. "An overview of lipid based vesicular systems: stability and regulatory considerations." GSC Biological and Pharmaceutical Sciences 21, no. 3 (2022): 053–61. https://doi.org/10.5281/zenodo.7653074.

Full text

Abstract:

Lipid based drug delivery systems are used to encapsulate the active substance within or interior space of the lipid bilayer. The lipid-based drug products are designed to improve the stability in-vivo and pharmacokinetics behavior of active substances. However, understanding of the factors that affect the stability is critical for rationale development of lipid based drug delivery systems with desired pharmacokinetics and bio-distribution. Lyophilization is one primary approach to improve the stability of lipid based systems. The article presents an overview of the characteristics of the lipi

APA, Harvard, Vancouver, ISO, and other styles

42

Bindhani, Sabitri, S. Mohapatra, and R. K. Kar. "Self Emulsifying Drug Delivery System: A Recent Approach." Asian Journal of Chemistry 31, no. 4 (2019): 751–59. http://dx.doi.org/10.14233/ajchem.2019.21569.

Full text

Abstract:

In recent years, nearly 40 % newer drugs compounds are hydrophobic in nature, which is a major challenge now-a-days for oral drug delivering due to low aqueous solubility. Lipid based drug delivery system is one of the favourable approach for poorly soluble compounds which can improve the drug absorption and oral bioavailability. Due to ion-pairing with appropriate surfactant and co-surfactant the macromolecular drug molecular oil droplet being found in the gut flow oral absorption which sufficiently stable towards lipase. Due to the formation of emulsified drug in micron level, it can efficie

APA, Harvard, Vancouver, ISO, and other styles

43

GR1, Godge. "An Overview of Nanocochleates for Improving Oral Absorption Using a Phospolipid-Based Drug Delivery System." Bioequivalence & Bioavailability International Journal 8, no. 2 (2024): 1–11. http://dx.doi.org/10.23880/beba-16000236.

Full text

Abstract:

A novel approach to oral and systemic drug delivery is nanaocochleate. It is a brand-new lipid-based system that offers a distinct technological platform appropriate for the systemic and oral delivery of numerous compounds with significant biologically therapeutic properties, such as medications, genes, and vaccine antigens. The technology of nanocochleate formulation is especially useful for hydrophobic macromolecules and small molecules with low oral bioavailability, as well as those that are negatively or positively charged. Research on the proof-of-principle of cochleate-mediated oral deli

APA, Harvard, Vancouver, ISO, and other styles

44

Dhamore, Harshada Gorakh, Assist Prof Kalpana S. Kale, and Dr Megha Salve. "Liposomal Drug Delivery System." International Journal of Pharmaceutical Research and Applications 09, no. 06 (2024): 502–9. https://doi.org/10.35629/4494-0906502509.

Full text

Abstract:

Liposomes have been considered promising and versatile drug vesicles. Compared with traditional drug delivery systems, liposomes exhibit better properties, including site-targeting, sustained or controlled release, protection of drugs from degradation and clearance, superior therapeutic effects, and lower toxic side effects. Given these merits, several liposomal drug products have been successfully approved and used in clinics over the last couple of decades. In this review, the liposomal drug products approved by the U.S. Food and Drug Administration (FDA) and European Medicines. Agency (EMA)

APA, Harvard, Vancouver, ISO, and other styles

45

Keerthi, R.*1 Preetha S. Panicker2 Farsana.P. P.3 Nasrin Nasir4. "Cubosome As Novel Drug Delivery System." International Journal in Pharmaceutical Sciences 2, no. 7 (2024): 1053–58. https://doi.org/10.5281/zenodo.12739661.

Full text

Abstract:

Cubosomes, a unique class of lipid-based vesicles, have emerged as promising candidates for drug delivery applications. Similar to liposomes, cubosomes self-assemble from amphiphilic lipids in the presence of stabilizers. Since their discovery, researchers have shown significant interest in their potential to transport therapeutic agents. Cubosomes offer versatility in terms of administration routes, including oral, ocular, transdermal, and even chemotherapy. Their well-defined cubic structure provides several advantages for drug nano formulations, particularly in cancer treatment. The most co

APA, Harvard, Vancouver, ISO, and other styles

46

OM UDAY CHIDDARWAR, KASHISH DINESH JESWANI, DEEPAK S. MOHALE, and A. V. CHANDEWAR. "Nanoparticle-based drug delivery systems: An efficient system for the treatment of chronic diseases." World Journal of Biology Pharmacy and Health Sciences 20, no. 3 (2024): 358–74. https://doi.org/10.30574/wjbphs.2024.20.3.1038.

Full text

Abstract:

Nanoparticle-based drug delivery systems form an integral component in modern medicine since they respond to major problems undermining traditional pharmacotherapeutic techniques, such as poor bioavailability, toxicity, and poor targeting of the desired drug location. This review also looks into the different types of nanoparticles: liposomes, polymeric nanoparticles, dendrimers and solid lipid nanoparticles, and how they work such as: targeting, drug delivery, release of drug, and tissue penetration. Some of the FDA-approved drugs that incorporated nanotechnology are Doxil; Abraxane; Onivyde;

APA, Harvard, Vancouver, ISO, and other styles

47

Nguyen, Thi-Thao-Linh, and Han-Joo Maeng. "Pharmacokinetics and Pharmacodynamics of Intranasal Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Nose-to-Brain Delivery." Pharmaceutics 14, no. 3 (2022): 572. http://dx.doi.org/10.3390/pharmaceutics14030572.

Full text

Abstract:

Nose-to-brain drug delivery has been of great interest for the treatment of many central nervous system (CNS) diseases and psychiatric disorders over past decades. Several nasally administered formulations have been developed to circumvent the blood-brain barrier and directly deliver drugs to the CNS through the olfactory and trigeminal pathways. However, the nasal mucosa’s drug absorption is insufficient and the volume of the nasal cavity is small, which, in combination, make nose-to-brain drug delivery challenging. These problems could be minimized using formulations based on solid lipid nan

APA, Harvard, Vancouver, ISO, and other styles

48

YILMAZ USTA, Duygu, and Zeynep Şafak TEKSİN. "Lipid Based Delivery Systems-I: Overview of Self-Emulsifying Drug Delivery System Formulations: Traditional Review." Journal of Literature Pharmacy Sciences 13, no. 3 (2024): 165–76. http://dx.doi.org/10.5336/pharmsci.2024-104970.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Qamar, Zufika, Farheen Fatima Qizilbash, Mohammad Kashif Iqubal, et al. "Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective." Recent Patents on Drug Delivery & Formulation 13, no. 4 (2020): 246–54. http://dx.doi.org/10.2174/1872211314666191224115211.

Full text

Abstract:

The structure of the eye is very complex in nature which makes it a challenging task for pharmaceutical researchers to deliver the drug at the desired sites via different routes of administration. The development of the nano-based system helped in delivering the drug in the desired concentration. Improvement in penetration property, bioavailability, and residence time has all been achieved by encapsulating drugs into liposomes, dendrimers, solid lipid nanoparticle, nanostructured lipid carrier, nanoemulsion, and nanosuspension. This review puts emphasis on the need for nanomedicine for ocular

APA, Harvard, Vancouver, ISO, and other styles

50

Gugleva, Viliana, and Velichka Andonova. "Drug delivery to the brain – lipid nanoparticles-based approach." Pharmacia 70, no. (1) (2023): 113–20. https://doi.org/10.3897/pharmacia.70.e98838.

Full text

Abstract:

The complex structure of the human brain defines it as one of the most inaccessible organs in terms of drug delivery. The blood-brain barrier (BBB) represents a microvascular network involved in transporting substances between the blood and the central nervous system (CNS) – enabling the entry of nutrients and simultaneously restricting the influx of pathogens and toxins. However, its role as a protective shield for CNS also restricts drug access to the brain. Since many drugs cannot cross the BBB due to unsuitable physicochemical characteristics (i.e., high molecular weight, aqueous solubilit

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!