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Journal articles on the topic 'Lipid-core polymeric nanoparticles'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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1

ZHANG, LI, and LIANGFANG ZHANG. "LIPID–POLYMER HYBRID NANOPARTICLES: SYNTHESIS, CHARACTERIZATION AND APPLICATIONS." Nano LIFE 01, no. 01n02 (2010): 163–73. http://dx.doi.org/10.1142/s179398441000016x.

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Nanotechnology has been extensively explored in the past decade to develop a myriad of functional nanostructures to facilitate the delivery of therapeutic and imaging agents for various medical applications. Liposomes and polymeric nanoparticles represent two primary delivery vehicles that are currently under investigation. While many advantages of these two particle platforms have been disclosed, some intrinsic limitations remain to limit their applications at certain extent. Recently, a new type of nanoparticle platform, named lipid–polymer hybrid nanoparticle, has been developed that combin
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2

Islam, Mohammad Ariful, Emma K. G. Reesor, Yingjie Xu, Harshal R. Zope, Bruce R. Zetter, and Jinjun Shi. "Biomaterials for mRNA delivery." Biomaterials Science 3, no. 12 (2015): 1519–33. http://dx.doi.org/10.1039/c5bm00198f.

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Schematic representation of various biomaterial-based systems for mRNA delivery: (a) protamine–mRNA complex; (b) lipid nanoparticle; (c) lipid nanoparticle with inorganic compounds (e.g.apatite); (d) cationic polymeric nanoparticle; (e) lipid–polymer hybrid nanoparticles including (i) mRNA–polymer complex core surrounded by a lipid shell and (ii) polymer core surrounded by a lipid shell with mRNA absorbed onto the surface; and (f) gold nanoparticle.
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3

Yu, Deng-Guang, Kenneth White, Nicholas Chatterton, Ying Li, Lingling Li, and Xia Wang. "Structural lipid nanoparticles self-assembled from electrospun core–shell polymeric nanocomposites." RSC Advances 5, no. 13 (2015): 9462–66. http://dx.doi.org/10.1039/c4ra14001j.

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4

Patel, Ravi R., Gayasuddin Khan, Sundeep Chaurasia, Nagendra Kumar, and Brahmeshwar Mishra. "Rationally developed core–shell polymeric-lipid hybrid nanoparticles as a delivery vehicle for cromolyn sodium: implications of lipid envelop on in vitro and in vivo behaviour of nanoparticles upon oral administration." RSC Advances 5, no. 93 (2015): 76491–506. http://dx.doi.org/10.1039/c5ra12732g.

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In the present study, cromolyn sodium, a highly water soluble molecule was encapsulated into rationally designed, core–shell polymeric-lipid hybrid nanoparticles for enhancing its oral bioavailability, by improving its intestinal permeability.
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5

Raman, Subashini, Syed Mahmood, and Azizur Rahman. "A Review on Lipid- Polymer Hybrid Nanoparticles and Preparation with Recent Update." Materials Science Forum 981 (March 2020): 322–27. http://dx.doi.org/10.4028/www.scientific.net/msf.981.322.

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Ongoing progression in nanotechnology has demonstrated that nanoparticles have indicated promising potential as in delivering the drug. The acceptance of nanoparticles and their applications also reported in clinical advancement to upgrade and improve the pharmacokinetic and pharmacodynamics properties of therapeutic compounds. In this review, we talk about the next-generation core-shell nanostructures like lipid-polymer hybrid nanoparticles (LHNPs) and their application and formulation aspects. Conceptually, derived from both polymeric nanoparticles and liposome, which gave them a name of hyb
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6

Bou, Sophie, Xinyue Wang, Nicolas Anton, Redouane Bouchaala, Andrey S. Klymchenko, and Mayeul Collot. "Lipid-core/polymer-shell hybrid nanoparticles: synthesis and characterization by fluorescence labeling and electrophoresis." Soft Matter 16, no. 17 (2020): 4173–81. http://dx.doi.org/10.1039/d0sm00077a.

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New hybrid nanoparticles have been obtained by simple nanoprecipitation using fluorescent labeling of both the oily core (BODIPY) and the polymeric shell (rhodamine) thus allowing the use of electrophoresis to assess their formation and stability.
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7

Sun, Jiashu, Lu Zhang, Jiuling Wang, et al. "Tunable Rigidity of (Polymeric Core)-(Lipid Shell) Nanoparticles for Regulated Cellular Uptake." Advanced Materials 27, no. 8 (2014): 1402–7. http://dx.doi.org/10.1002/adma.201404788.

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8

Sivadasan, Durgaramani, Muhammad Hadi Sultan, Osama Madkhali, Yosif Almoshari, and Neelaveni Thangavel. "Polymeric Lipid Hybrid Nanoparticles (PLNs) as Emerging Drug Delivery Platform—A Comprehensive Review of Their Properties, Preparation Methods, and Therapeutic Applications." Pharmaceutics 13, no. 8 (2021): 1291. http://dx.doi.org/10.3390/pharmaceutics13081291.

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Polymeric lipid hybrid nanoparticles (PLNs) are core–shell nanoparticles made up of a polymeric kernel and lipid/lipid–PEG shells that have the physical stability and biocompatibility of both polymeric nanoparticles and liposomes. PLNs have emerged as a highly potent and promising nanocarrier for a variety of biomedical uses, including drug delivery and biomedical imaging, owing to recent developments in nanomedicine. In contrast with other forms of drug delivery systems, PLNs have been regarded as seamless and stable because they are simple to prepare and exhibit excellent stability. Natural,
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9

ZHENG, MINGBIN, PING GONG, DONGXUE JIA, CUIFANG ZHENG, YIFAN MA, and LINTAO CAI. "PLGA–LECITHIN–PEG CORE-SHELL NANOPARTICLES FOR CANCER TARGETED THERAPY." Nano LIFE 02, no. 01 (2012): 1250002. http://dx.doi.org/10.1142/s1793984411000359.

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We reported the development of multifunctional poly (lactic-co-glycolic acid) (PLGA)-lecithin-polyethylene glycol (PEG) core-shell nanoparticles (NPs) that combined the beneficial properties of liposome and polymeric NPs for chemotherapeutics delivery. The particle size, surface charge and surface functional groups were easily tunable in highly reproducible manner by various formulation parameters such as lipid/polymer, 1, 2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE)-PEG- COOH /lecithin, DSPE-PEG- COOH /DSPE-PEG- NH2 mass ratio and modification of terminal groups of DSPE-PEG. We encaps
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10

You, Jian, Jun Zhao, Xiaoxia Wen, et al. "Chemoradiation therapy using cyclopamine-loaded liquid–lipid nanoparticles and lutetium-177-labeled core-crosslinked polymeric micelles." Journal of Controlled Release 202 (March 2015): 40–48. http://dx.doi.org/10.1016/j.jconrel.2015.01.031.

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11

Bochicchio, Sabrina, Annalisa Dalmoro, Paolo Bertoncin, Gaetano Lamberti, Rouslan I. Moustafine, and Anna Angela Barba. "Design and production of hybrid nanoparticles with polymeric-lipid shell–core structures: conventional and next-generation approaches." RSC Advances 8, no. 60 (2018): 34614–24. http://dx.doi.org/10.1039/c8ra07069e.

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12

Lei, Yao, Furong Zhao, Junjun Shao, et al. "Application of built-in adjuvants for epitope-based vaccines." PeerJ 6 (January 14, 2019): e6185. http://dx.doi.org/10.7717/peerj.6185.

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Several studies have shown that epitope vaccines exhibit substantial advantages over conventional vaccines. However, epitope vaccines are associated with limited immunity, which can be overcome by conjugating antigenic epitopes with built-in adjuvants (e.g., some carrier proteins or new biomaterials) with special properties, including immunologic specificity, good biosecurity and biocompatibility, and the ability to vastly improve the immune response of epitope vaccines. When designing epitope vaccines, the following types of built-in adjuvants are typically considered: (1) pattern recognition
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13

Rana, Sarvjeet S., Shailendra Bhatt, Manish Kumar, et al. "Design and Optimization of Itraconazole Loaded SLN for Intranasal Administration Using Central Composite Design." Nanoscience & Nanotechnology-Asia 10, no. 6 (2020): 884–91. http://dx.doi.org/10.2174/2210681209666191111113112.

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Introduction: Solid Lipid nanoparticles (SLN) are comprising of a solid lipid core with a mean diameter between 50 and 1000 nm. SLN is an advanced carrier system to traditional colloidal carriers such as emulsion, liposomes, and polymeric microparticles. Objective: The objective of this study was to formulate SLN of Itraconazole (ITZ) for intranasal administration. Methods: ITZ-loaded SLN were prepared by high pressure homogenization technique using the Central Composite Design (CCD). The concentration of surfactant (X1) and drug to lipid ratio (X2) was considered as independent variables, whe
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14

Oh, Keun Sang, Sung Kyun Han, Hyun Suk Lee, et al. "Core/Shell Nanoparticles with Lecithin Lipid Cores for Protein Delivery." Biomacromolecules 7, no. 8 (2006): 2362–67. http://dx.doi.org/10.1021/bm060362k.

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15

Oh, Keun Sang, Kyung Eun Lee, Sung Sik Han, Sun Hang Cho, Dongmin Kim, and Soon Hong Yuk. "Formation of Core/Shell Nanoparticles with a Lipid Core and Their Application as a Drug Delivery System." Biomacromolecules 6, no. 2 (2005): 1062–67. http://dx.doi.org/10.1021/bm049234r.

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16

Deshpande, Pallav Kaushik, and Ragini Gothalwal. "FORMULATION AND EVALUATION OF NANOPARTICLES WITH NEURO PROTECTIVE CHEMICALS OF NATURAL AND SYNTHETIC ORIGIN." PARIPEX INDIAN JOURNAL OF RESEARCH, July 15, 2021, 11–14. http://dx.doi.org/10.36106/paripex/4207479.

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Most of the active phytoconstituents under development are poorly water soluble or have poor bioavailability . Nanotechnology is an approach to overcome the challenges of conventional drug delivery systems and limitations of phytochemicals. Solid Lipid nanoparticles show interesting features concerning therapeutic purposes. The main advantage is that they are prepared with physiologically well-tolerated lipids.Solid Lipid Nanoparticles (SLNs) as novel lipid based nanocarriers with size range between 10 to 1000nm. SLNs were introduced to overcome problems of polymeric nanoparticles.In present r
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17

Esim, Ozge, and Canan Hascicek. "Lipid-Coated Nanosized Drug Delivery Systems For An Effective Cancer Therapy." Current Drug Delivery 17 (May 12, 2020). http://dx.doi.org/10.2174/1567201817666200512104441.

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: Currently, despite many active compounds have been introduced to the treatment, cancer remains one of the most vital causes of mortality and reduced quality of life. Conventional cancer treatments may have undesirable consequences due to the continuously differentiating, dynamic and heterogeneous nature of cancer. Recent advances in the field of cancer treatment have promoted the development of several novel nanoformulations. Among them, the lipid coated nanosized drug delivery systems have gained an increasing attention by the researchers in this field owing to the attractive properties suc
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18

Asuman Bozkır, Burcu Devrim. "Preparation and Characterization of Protein-loaded Lipid-polymer Hybrid Nanoparticles with Polycaprolactone as Polymeric Core Material." Journal of Biomolecular Research & Therapeutics 03, no. 03 (2014). http://dx.doi.org/10.4172/2167-7956.1000115.

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19

Araya-Sibaja, Andrea Mariela, Krissia Wilhelm, Gustavo Adolfo González-Aguilar, et al. "Curcumin loaded and co-loaded nanosystems: A review from a biological activity enhancement perspective." Pharmaceutical Nanotechnology 08 (December 28, 2020). http://dx.doi.org/10.2174/2211738508666201228150659.

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Background: Curcumin is a natural phenolic compound exhibiting multiple bioactivities that have been evaluated in vitro, in vivo as well as through clinical studies in humans. Some of them include antimicrobial, antioxidant, anti-inflammatory and central nervous system protective effects. Further, curcumin is considered a Generally Recognized as Safe substance because of its low toxicity. However, its molecular structure is susceptible to changes in pH, oxidation, photodegradation, low aqueous solubility and biotransformation compromising its bioavailability, drawbacks that have been successfu
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20

van der Weide, Hessel, Unai Cossío, Raquel Gracia, et al. "Therapeutic Efficacy of Novel Antimicrobial Peptide AA139-Nanomedicines in a Multidrug-Resistant Klebsiella pneumoniae Pneumonia-Septicemia Model in Rats." Antimicrobial Agents and Chemotherapy 64, no. 9 (2020). http://dx.doi.org/10.1128/aac.00517-20.

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ABSTRACT Antimicrobial peptides (AMPs) have seen limited clinical use as antimicrobial agents, largely due to issues relating to toxicity, short biological half-life, and lack of efficacy against Gram-negative bacteria. However, the development of novel AMP-nanomedicines, i.e., AMPs entrapped in nanoparticles, has the potential to ameliorate these clinical problems. The authors investigated two novel nanomedicines based on AA139, an AMP currently in development for the treatment of multidrug-resistant Gram-negative infections. AA139 was entrapped in polymeric nanoparticles (PNPs) or lipid-core
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21

Ghaghelestani, Tahereh Najafi, Nafiseh Farhadian, and Nafiseh Binesh. "Preparation a core‐shell lipid/polymer nanoparticle containing Isotretinoin drug with pH sensitive property: A response surface methodology study." Journal of Applied Polymer Science, March 22, 2021, 50734. http://dx.doi.org/10.1002/app.50734.

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22

Demchuk, M. B., N. P. Darzuli, T. A. Hroshovyi та S. V. Demchuk. "СУЧАСНИЙ СТАН СТВОРЕННЯ, ВИРОБНИЦТВА ТА ДОСЛІДЖЕННЯ ТАБЛЕТОВАНИХ ЛІКАРСЬКИХ ПРЕПАРАТІВ Повідомлення 20. Характеристика процесу створення та дослідження гастроретентивних систем доставки лікарських речовин." Фармацевтичний часопис, № 4 (19 січня 2016). http://dx.doi.org/10.11603/2312-0967.2015.4.5563.

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<p align="center"><strong>MODERN STATE OF CREATION, PRODUCTION AND RESEARCH OF DRUGS</strong></p><p align="center"><strong>M.</strong><strong>B. </strong><strong>Demchuk, </strong><strong>N.</strong><strong>P. </strong><strong>Darzuli, </strong><strong>T.</strong><strong>A. </strong><strong>Hroshovyi, S.V. Demchuk<sup>1</sup></strong></p><p align="center">TernopilStateMedicalUniversityby I.Ya. Horbachevsky</p><p align="center
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