Relevant bibliographies by topics / Lipid Droplet

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Lipid Droplet'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 July 2025

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Journal articles on the topic "Lipid Droplet"

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Jin, Yi, Zhuqing Ren, Yanjie Tan, Pengxiang Zhao, and Jian Wu. "Motility Plays an Important Role in the Lifetime of Mammalian Lipid Droplets." International Journal of Molecular Sciences 22, no. 8 (2021): 3802. http://dx.doi.org/10.3390/ijms22083802.

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The lipid droplet is a kind of organelle that stores neutral lipids in cells. Recent studies have found that in addition to energy storage, lipid droplets also play an important role in biological processes such as resistance to stress, immunity, cell proliferation, apoptosis, and signal transduction. Lipid droplets are formed at the endoplasmic reticulum, and mature lipid droplets participate in various cellular processes. Lipid droplets are decomposed by lipase and lysosomes. In the life of a lipid droplet, the most important thing is to interact with other organelles, including the endoplas
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Adeyo, Oludotun, Patrick J. Horn, SungKyung Lee, et al. "The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets." Journal of Cell Biology 192, no. 6 (2011): 1043–55. http://dx.doi.org/10.1083/jcb.201010111.

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Lipins are phosphatidate phosphatases that generate diacylglycerol (DAG). In this study, we report that yeast lipin, Pah1p, controls the formation of cytosolic lipid droplets. Disruption of PAH1 resulted in a 63% decrease in droplet number, although total neutral lipid levels did not change. This was accompanied by an accumulation of neutral lipids in the endoplasmic reticulum (ER). The droplet biogenesis defect was not a result of alterations in neutral lipid ratios. No droplets were visible in the absence of both PAH1 and steryl acyltransferases when grown in glucose medium, even though the
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Cabodevilla, Ainara G., Ni Son, and Ira J. Goldberg. "Intracellular lipase and regulation of the lipid droplet." Current Opinion in Lipidology 35, no. 2 (2024): 85–92. http://dx.doi.org/10.1097/mol.0000000000000918.

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Purpose of review Lipid droplets are increasingly recognized as distinct intracellular organelles that have functions exclusive to the storage of energetic lipids. Lipid droplets modulate macrophage inflammatory phenotype, control the availability of energy for muscle function, store excess lipid, sequester toxic lipids, modulate mitochondrial activity, and allow transfer of fatty acids between tissues. Recent findings There have been several major advances in our understanding of the formation, dissolution, and function of this organelle during the past two years. These include new informatio
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DiDonato, Deanna, and Dawn L. Brasaemle. "Fixation Methods for the Study of Lipid Droplets by Immunofluorescence Microscopy." Journal of Histochemistry & Cytochemistry 51, no. 6 (2003): 773–80. http://dx.doi.org/10.1177/002215540305100608.

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The study of proteins associated with lipid droplets in adipocytes and many other cells is a rapidly developing area of inquiry. Although lipid droplets are easily visible by light microscopy, few standardized microscopy methods have been developed. Several methods of chemical fixation have recently been used to preserve cell structure before visualization of lipid droplets by light microscopy. We tested the most commonly used methods to compare the effects of the fixatives on cellular lipid content and lipid droplet structure. Cold methanol fixation has traditionally been used before visualiz
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Gaunt, Eleanor R., Qifeng Zhang, Winsome Cheung, Michael J. O. Wakelam, Andrew M. L. Lever, and Ulrich Desselberger. "Lipidome analysis of rotavirus-infected cells confirms the close interaction of lipid droplets with viroplasms." Journal of General Virology 94, no. 7 (2013): 1576–86. http://dx.doi.org/10.1099/vir.0.049635-0.

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Rotaviruses (RVs) cause acute gastroenteritis in infants and young children, and are globally distributed. Within the infected host cell, RVs establish replication complexes in viroplasms (‘viral factories’) to which lipid droplet organelles are recruited. To further understand this recently discovered phenomenon, the lipidomes of RV-infected and uninfected MA104 cells were investigated. Cell lysates were subjected to equilibrium ultracentrifugation through iodixanol gradients. Fourteen different classes of lipids were differentiated by mass spectrometry. The concentrations of virtually all li
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Robenek, Horst, Insa Buers, Mirko J. Robenek, et al. "Topography of Lipid Droplet-Associated Proteins: Insights from Freeze-Fracture Replica Immunogold Labeling." Journal of Lipids 2011 (2011): 1–10. http://dx.doi.org/10.1155/2011/409371.

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Lipid droplets are not merely storage depots for superfluous intracellular lipids in times of hyperlipidemic stress, but metabolically active organelles involved in cellular homeostasis. Our concepts on the metabolic functions of lipid droplets have come from studies on lipid droplet-associated proteins. This realization has made the study of proteins, such as PAT family proteins, caveolins, and several others that are targeted to lipid droplets, an intriguing and rapidly developing area of intensive inquiry. Our existing understanding of the structure, protein organization, and biogenesis of
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Yang, Xing, Kylie R. Dunning, Linda L. Y. Wu, et al. "Identification of Perilipin-2 as a lipid droplet protein regulated in oocytes during maturation." Reproduction, Fertility and Development 22, no. 8 (2010): 1262. http://dx.doi.org/10.1071/rd10091.

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Lipid droplet proteins regulate the storage and utilisation of intracellular lipids. Evidence is emerging that oocyte lipid utilisation impacts embryo development, but lipid droplet proteins have not been studied in oocytes. The aim of the present study was to characterise the size and localisation of lipid droplets in mouse oocytes during the periovulatory period and to identify lipid droplet proteins as potential biomarkers of oocyte lipid content. Oocyte lipid droplets, visualised using a novel method of staining cumulus–oocyte complexes (COCs) with BODIPY 493/503, were small and diffuse in
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Liu, Yu, Yitao Xi, Yanyu Lv, et al. "The Plasma Membrane H+ ATPase CsPMA2 Regulates Lipid Droplet Formation, Appressorial Development and Virulence in Colletotrichum siamense." International Journal of Molecular Sciences 24, no. 24 (2023): 17337. http://dx.doi.org/10.3390/ijms242417337.

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Plasma membrane H+-ATPases (PMAs) play an important role in the pathogenicity of pathogenic fungi. Lipid droplets are important storage sites for neutral lipids in fungal conidia and hyphae and can be used by plant pathogenic fungi for infection. However, the relationship between plasma membrane H+-ATPase, lipid droplets and virulence remains unclear. Here, we characterized a plasma membrane H+-ATPase, CsPMA2, that plays a key role in lipid droplet formation, appresorial development and virulence in C. siamense. Deletion of CsPMA2 impaired C. siamense conidial size, conidial germination, appre
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Zhang, Yuchen, Yiqing Chen, Cheng Zhuang, Jingxuan Qi, Robert Chunhua Zhao, and Jiao Wang. "Lipid droplets in the nervous system: involvement in cell metabolic homeostasis." Neural Regeneration Research 20, no. 3 (2024): 740–50. http://dx.doi.org/10.4103/nrr.nrr-d-23-01401.

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Lipid droplets serve as primary storage organelles for neutral lipids in neurons, glial cells, and other cells in the nervous system. Lipid droplet formation begins with the synthesis of neutral lipids in the endoplasmic reticulum. Previously, lipid droplets were recognized for their role in maintaining lipid metabolism and energy homeostasis; however, recent research has shown that lipid droplets are highly adaptive organelles with diverse functions in the nervous system. In addition to their role in regulating cell metabolism, lipid droplets play a protective role in various cellular stress
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Kang, Sun Woo Sophie, Victoria C. Cogger, David G. Le Couteur, and Dong Fu. "Multiple cellular pathways regulate lipid droplet homeostasis for the establishment of polarity in collagen sandwich-cultured hepatocytes." American Journal of Physiology-Cell Physiology 317, no. 5 (2019): C942—C952. http://dx.doi.org/10.1152/ajpcell.00051.2019.

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Hepatocyte polarization is energy dependent. The establishment of polarization in collagen sandwich culture of hepatocytes requires utilization of lipid droplets and mitochondrial β-oxidation to supply ATP. Multiple cellular pathways are involved in lipid droplet homeostasis; however, mechanistic insights of how hepatocytes utilize lipid droplets during polarization remain elusive. The current study investigated the effects of various pathways involved in lipid droplet homeostasis on bioenergetics during hepatocyte polarization. The results showed that hepatocytes were dependent on lipolysis o
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Dissertations / Theses on the topic "Lipid Droplet"

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Deeney, Jude T. "Micro lipid droplet precursors of milk lipid globules." Thesis, Virginia Tech, 1985. http://hdl.handle.net/10919/45673.

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The lipid in milk (milk fat) is found in the form of droplets known as milk lipid globules (MLG). These milk lipid globules are encompassed by a unit membrane known as the milk lipid globule membrane (MLGM) which is derived from the apical plasma membrane of the mammary epithelial cell during secretion. In lactating mammary epithelial cells, immediate precursors of milk lipid globules appear to be cytoplasmic lipid droplets (CLD). These cytoplasmic lipid droplets have diameters >1 μm and are characterized by an electron dense, granular surface coat. A previously unrecognized group of
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Krahmer, Natalie. "Analysis of Lipid Droplet Proteins and their Contribution to Phospholipid Homeostasis during Lipid Droplet Expansion." Diss., lmu, 2011. http://nbn-resolving.de/urn:nbn:de:bvb:19-133305.

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Danial, John Shokri Hanna. "Imaging lipid phase separation on droplet interface bilayers." Thesis, University of Oxford, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.711943.

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Du, Xiaoli [Verfasser]. "Characterization of Lipid Droplets and Functional Analysis of Lipid Droplet-Associated Proteins in Dictyostelium discoideum / Xiaoli Du." Kassel : Universitätsbibliothek Kassel, 2013. http://d-nb.info/1038246776/34.

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Grachan, Jeremy J. "Characterization of Hypoxia-Inducible Lipid Droplet Associated Protein (HILPDA) Dependent Lipid Droplet Abundance in Pancreatic Cancer Tumors Cells." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1586437335477715.

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Krahmer, Natalie [Verfasser], and Stefan [Akademischer Betreuer] Jentsch. "Analysis of Lipid Droplet Proteins and their Contribution to Phospholipid Homeostasis during Lipid Droplet Expansion / Natalie Krahmer. Betreuer: Stefan Jentsch." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2011. http://d-nb.info/1015170366/34.

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Danial, John Shokri Hanna. "Imaging lipid phase separation in droplet interface bilayers." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:34bb015f-2bc1-43bb-bc29-850e0b55edac.

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The spatiotemporal organization of membrane proteins is implicated in cellular trafficking, signalling and reception. It was proposed that biological membranes partition into lipid rafts that can promote and control the organization of membrane proteins to localize the mentioned processes. Lipid rafts are thought to be transient (microseconds) and small (nanometers), rendering their detection a challenging task. To circumvent this problem, multi-component artificial membrane systems are deployed to study the segregation of lipids at longer time and length scales. In this thesis, multi-componen
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McClinchie, Elizabeth A. "Homologs of Mammalian Lysosomal Lipase in Arabidopsis and Their Roles in Lipid Droplet Dynamics." Thesis, University of North Texas, 2017. https://digital.library.unt.edu/ark:/67531/metadc1062826/.

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Lipid droplets (LDs) are organelles with many functions in cells and numerous protein interactors facilitate their biogenesis, maintenance, and turnover. The mammalian lipase responsible for LD turnover during lipophagy, LipA, has two candidate homologs in Arabidopsis: MPL1 and LIP1. One or both of these plant homologs may function in a similar manner to mammalian LipA, providing an LD breakdown pathway. To test this hypothesis, wild type (WT) Arabidopsis plants, MPL1 over-expressing (OE) mutants, and T-DNA insertion mutants of MPL1 (mpl1) and LIP1 (lip1) were examined for LD phenotypes in no
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Beller, Mathias. "Identification and characterization of Drosophila lipid droplet-associated proteins." [S.l. : s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=974177822.

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Nicolaou, Giovanna. "Mechanisms of bacteria-mediated lipid droplet formation in macrophages." Thesis, University of Leicester, 2013. http://hdl.handle.net/2381/28530.

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Atherosclerosis is a chronic inflammatory disease of the arteries that represents the root cause of the majority of heart attacks and strokes. The accumulation of lipid droplets (LDs) in macrophages and their subsequent transformation into foam cells is one of the key steps in the development of atherosclerotic lesions. It has been traditionally thought that this process is largely dependent on the accumulation of oxidised low-density lipoprotein (OxLDL) via uptake by macrophage scavenger receptors. However, as DNA signatures from a wide array of bacterial species have been identified in human
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Books on the topic "Lipid Droplet"

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Garcia, Enrique Jose. ER stress and lipid droplet-dependent proteostasis in response to lipid stress in yeast and a novel congenital muscular dystrophy. [publisher not identified], 2019.

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D'Ambrosio, Diana N. Physiology and Pathophysiology of Retinoid and Lipid Storage in Mouse Hepatic Stellate Cell Lipid Droplets. [publisher not identified], 2011.

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Catalá, Angel. Lipid Droplets. Nova Science Publishers, Incorporated, 2019.

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Lipid Droplets. Elsevier, 2013. http://dx.doi.org/10.1016/c2012-0-03381-9.

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Li, Peng, and H. Robert Yang. Lipid Droplets. Elsevier Science & Technology Books, 2013.

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Li, Peng, and H. Robert Yang. Lipid Droplets: Methods in Cell Biology. Elsevier Science & Technology Books, 2013.

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Book chapters on the topic "Lipid Droplet"

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Dugail, Isabelle, and Soizic Le Lay. "Adipocyte Lipid Droplet Physiology." In Physiology and Physiopathology of Adipose Tissue. Springer Paris, 2012. http://dx.doi.org/10.1007/978-2-8178-0343-2_9.

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Imai, Yumi, Michelle B. Trevino, and Rexford S. Ahima. "Lipid Droplet Proteins and Hepatic Lipid Metabolism." In Hepatic De Novo Lipogenesis and Regulation of Metabolism. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-25065-6_8.

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Ohsaki, Yuki, Kamil Sołtysik, and Toyoshi Fujimoto. "The Lipid Droplet and the Endoplasmic Reticulum." In Advances in Experimental Medicine and Biology. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-4567-7_8.

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Booth, Michael J., Vanessa Restrepo Schild, Florence G. Downs, and Hagan Bayley. "Droplet Networks, from Lipid Bilayers to Synthetic Tissues." In Encyclopedia of Biophysics. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-642-35943-9_567-1.

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Olofsson, Sven-Olof, Pontus Boström, Jens Lagerstedt, et al. "The Lipid Droplet: a Dynamic Organelle, not only Involved in the Storage and Turnover of Lipids." In Cellular Lipid Metabolism. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-00300-4_1.

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Yu, Liqing, Yi Li, Alison Grisé, and Huan Wang. "CGI-58: Versatile Regulator of Intracellular Lipid Droplet Homeostasis." In Advances in Experimental Medicine and Biology. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-6082-8_13.

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Wolinski, Heimo, and Sepp D. Kohlwein. "Microscopic Analysis of Lipid Droplet Metabolism and Dynamics in Yeast." In Membrane Trafficking. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-261-8_11.

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Frohnmayer, Johannes P., Marian Weiss, Lucia T. Benk, et al. "Droplet-stabilized giant lipid vesicles as compartments for synthetic biology." In The Giant Vesicle Book. CRC Press, 2019. http://dx.doi.org/10.1201/9781315152516-30.

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Costa, Marlene, Sonia Losada-Barreiro, Carlos Bravo-Díaz, and Fátima Paiva-Martins. "Effects of Emulsion Droplet Size on the Distribution and Efficiency of Antioxidants." In Lipid Oxidation in Food and Biological Systems. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-87222-9_10.

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Bersuker, Kirill, and James A. Olzmann. "Identification of Lipid Droplet Proteomes by Proximity Labeling Proteomics Using APEX2." In Methods in Molecular Biology. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9537-0_5.

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Conference papers on the topic "Lipid Droplet"

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Zhang, Hao, and Zachary J. Smith. "Rapid intracellular detection and analysis of lipid droplets' morpho-chemical composition by phase-guided Raman sampling." In Optics in Health Care and Biomedical Optics XIV, edited by Qingming Luo, Xingde Li, Ying Gu, and Dan Zhu. SPIE, 2024. http://dx.doi.org/10.1117/12.3034573.

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Tonooka, T., and S. Takeuchi. "Lipid bilayer on a droplet: Formation of lipid bilayers on a droplet array." In 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2012. http://dx.doi.org/10.1109/memsys.2012.6170251.

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Venkatesan, Guru, and Andy Sarles. "Understanding Micro-Droplet Interface Bilayers for Developing Bioinspired Sensors." In ASME 2013 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/smasis2013-3134.

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Droplet-based biomolecular arrays form the basis for a new class of bioinspired material system, whereby decreasing the sizes of the droplets and increasing the number of droplets can lead to higher functional density for the array. In this paper, we report on a non-microfluidic approach to form and connect nanoliter-to-femtoliter, lipid-coated aqueous droplets in oil to form micro-droplet interface bilayers (μDIBs). Two different modes of operation are reported for dispensing a wide range of droplet sizes (2–200μm radius). Due to the high surface-area-to-volume ratios of microdroplets at thes
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Nguyen, Mary-Anne, and Stephen A. Sarles. "Microfluidic Generation, Encapsulation and Characterization of Asymmetric Droplet Interface Bilayers." In ASME 2016 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/smasis2016-9034.

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Our research focuses on creating smart materials that utilize synthetic cell membranes assembled at liquid interfaces for autonomic sensing, actuation, and energy conversion. Unlike single membrane assemblies, systems featuring many membranes have the potential to offer multi-functionality, greater transduction sensitivity, and even emergent behaviors in response to environmental stimuli, similar to living tissue, which utilizes networks of highly packed cells to accomplish tasks. Here, we present for the first time a novel microfluidic platform capable of generating a stream of alternating dr
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Makhoul-Mansour, Michelle, Elio J. Challita, and Eric C. Freeman. "Chain Failure Events in Microfluidic Membrane Networks." In ASME 2016 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/smasis2016-9143.

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Multiple lipid encased water droplets may be linked together in oil to form large networks of droplet interface bilayers thus creating a new class of stimuli-responsive materials for applications in sensing, actuation, drug delivery, and tissue engineering. While single droplet interface bilayers have been extensively studied, comparatively little is known about their interaction in large networks. One particular problem of interest is understanding the impact of the coalescence of two neighboring droplets on the overall structural integrity of the network. Here, we propose a computational mod
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Tsuji, Yutaro, Ryuji Kawano, Toshihisa Osaki, et al. "Solution exchange of droplet contacting lipid bilayer system." In 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2012. http://dx.doi.org/10.1109/memsys.2012.6170327.

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Edgerton, Alex, Joseph Najem, and Donald Leo. "A Hydrogel-Based Droplet Interface Lipid Bilayer Network." In ASME 2014 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/smasis2014-7580.

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In this work, we present a process for the fabrication of meso-scale hydrogel-based lipid bilayer arrays. The hydrogels support lipid monolayers at an oil-water interface, and when brought together, form stable bilayers. The substrates are formed using 3D printed molds and include built-in, customizable circuits patterned with silver paint. The system can be adapted to varying network sizes and circuit designs, and new arrays are fabricated quickly and inexpensively using common laboratory techniques. An enclosed 3×3 array with 3 mm spacing between neighboring hydrogels and electrodes to indiv
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Sarles, Stephen A., and Donald J. Leo. "Durable Biomolecular Assemblies for Protein-Powered Device Concepts." In ASME 2009 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. ASMEDC, 2009. http://dx.doi.org/10.1115/smasis2009-1346.

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Physically encapsulated droplet-interface bilayers are formed by confining aqueous droplets surrounded by lipid mono-layers in connected compartments within a solid substrate. The droplets reside within each compartment and are positioned on fixed electrodes built into the solid substrate. Full encapsulation of the network is achieved with a solid cap that inserts into the substrate to form a closed volume. Encapsulated networks provide increased portability over unencapsulated networks by limiting droplet movement and by integrating the electrodes into the supporting fixture. The formation of
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Tamaddoni, Nima, and Stephen A. Sarles. "Mechanotransduction of Multi-Hair Droplet Arrays." In ASME 2014 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/smasis2014-7551.

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Early embodiments of droplet interface bilayer (DIB)-based hair cell sensors demonstrated the capability of sensing discrete and continuous perturbations, including single flicks and constant airflow, respectively, of a hair structure that is held in close proximity to a single lipid membrane. In those studies, the use of a single bilayer formed between a pair of droplets provided the necessary environment for studying the physical mechanism of mechanotransduction of a membrane-based sensor as well as the sensitivity and directionality of the assembly. More recently, we showed that additional
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Nguyen, Mary-Anne, and Stephen A. Sarles. "Micro-Encapsulation and Tuning of Biomolecular Unit Cell Networks." In ASME 2014 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/smasis2014-7583.

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The goal of our research is to fabricate an autonomic material system that provides compartmentalization and multi-bilayer networks for enabling collective biomolecular functionality, as is found in living cells and tissues. The material system is based on biomolecular unit cells, which consist of synthetic lipid bilayers formed at the interfaces of lipid-coated aqueous droplets submerged in oil and contained in a solid material. This paper focuses on microfluidic encapsulation of unit cells within a solid material and tuning the amount of contact between droplets, two approaches aimed at incr
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Reports on the topic "Lipid Droplet"

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Grumet, R., J. Burger, Y. Tadmor, et al. Cucumis fruit surface biology: Genetic analysis of fruit exocarp features in melon (C. melo) and cucumber (C. sativus). United States-Israel Binational Agricultural Research and Development Fund, 2020. http://dx.doi.org/10.32747/2020.8134155.bard.

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The fruit surface (exocarp) is a unique tissue with multiple roles influencing fruit growth and development, disease susceptibility, crop yield, post-harvest treatments, shipping and storage quality, and food safety. Furthermore, highly visible exocarp traits are the consumer's first exposure to the fruit, serving to identify fruit type, variety, attractiveness, and market value. Cucurbit fruit, including the closely related Cucumis species, melon (C. melo) and cucumber (C. sativus), exhibit tremendous diversity for fruit surface properties that are not present in model species. In this projec
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