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Journal articles on the topic 'Lipid metabolism disorders'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Strashok, L. A., O. V. Buznytska, and О. М. Meshkova. "Indicators of lipid metabolism disorders in the blood serum of adolescents with metabolic syndrome." Ukrainian Biochemical Journal 92, no. 6 (2020): 137–42. http://dx.doi.org/10.15407/ubj92.06.137.

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2

Sadykova, D. I., A. V. Susekov, I. V. Leontyeva, et al. "Lipid metabolism disorders and thyrotoxicosis." Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 65, no. 6 (2021): 91–97. http://dx.doi.org/10.21508/1027-4065-2020-65-6-91-97.

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Disorders of lipid metabolism in endocrine diseases are a frequent occurrence in the daily practice of a doctor and usually have secondary nature. In thyrotoxicosis they have normal or decreased level of total cholesterol and low-density lipoproteins. A clinical case of a patient with thyrotoxicosis, hypercholesterolemia and hypertriglyceridemia is presented. The clinical and laboratory results of the study of the child and his parents are presented. DNA testing was conducted to clarify the diagnosis and conduct differential diagnosis of dyslipidemia type. This case shows difficulties in the d

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3

Gieselmann, Volkmar. "Disorders of lysosomal lipid metabolism." Chemistry and Physics of Lipids 154 (August 2008): S18—S19. http://dx.doi.org/10.1016/j.chemphyslip.2008.05.049.

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4

Ferrer, María José, Aimé Florencia Silva, Giselle Adriana Abruzzese, Mariela Edith Velázquez, and Alicia Beatriz Motta. "Lipid Metabolism and Relevant Disorders to Female Reproductive Health." Current Medicinal Chemistry 28, no. 27 (2021): 5625–47. http://dx.doi.org/10.2174/0929867328666210106142912.

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Background: Lipids are essential components of cells that participate in metabolic and endocrine regulation and reproductive functions. The main organs where lipid regulation takes place are the liver and adipose tissue. Besides, when each tissue- specific action cannot be exerted, it could lead to several endocrine-metabolic disorders closely related to PCOS, such as non-alcoholic fatty liver disease (NAFLD) and obesity. Objective: This work aims to discuss the impact of lipid alterations on metabolic and reproductive health. Therefore, this review focus on the importance of carrying out an i

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5

Ma, Menghua, Fangli Gu, Zongcui Yue, et al. "Dendrobium huoshanense Improves Lipid Metabolism Disorder by Restoring Gut Flora and Metabolites in Mice Fed a High-Fat Diet." Journal of Food Biochemistry 2024 (February 5, 2024): 1–16. http://dx.doi.org/10.1155/2024/6245499.

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Lipid metabolism disorders are widely acknowledged as crucial risk factors for a range of metabolic diseases, including hyperlipidemia, obesity, nonalcoholic fatty liver disease, and atherosclerosis. Dysbiosis of the gut microbiota is considered a potential mechanism of action in lipid metabolism disorders. Dendrobium huoshanense C.Z. Tang et S.J. Cheng (DH), an important edible and medicinal Chinese herb, has been shown to regulate the gut flora disorders and improve intestinal health. However, DH inhibits lipid metabolism disorders by regulating the gut flora remains unclear. Therefore, we a

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6

Saito, Takao. "Abnormal Lipid Metabolism and Renal Disorders." Tohoku Journal of Experimental Medicine 181, no. 3 (1997): 321–37. http://dx.doi.org/10.1620/tjem.181.321.

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7

Wanders, R. J. A. "Peroxisomes, lipid metabolism, and peroxisomal disorders." Molecular Genetics and Metabolism 83, no. 1-2 (2004): 16–27. http://dx.doi.org/10.1016/j.ymgme.2004.08.016.

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8

Schuster, Herbert. "Molecular genetics of lipid metabolism disorders." Fresenius' Journal of Analytical Chemistry 343, no. 1 (1992): 36. http://dx.doi.org/10.1007/bf00331976.

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9

Serbeniuk, Anastasiia. "Research of Lipid Metabolism Disorders in Female Combatants." Family medicine. European practices, no. 3 (October 28, 2022): 12–15. http://dx.doi.org/10.30841/2786-720x.3.2022.273906.

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The objective: to find out the peculiarities of stress-induced changes in lipid metabolism indicators in women who have experienced concussion during combat operations. Study the state and morphostructure of adipose tissue. To analyze the relationship between lipid metabolism disorders and changes in reproductive health of female combatants. Materials and methods. The research was conducted at the Department of Obstetrics, Gynecology and Reproductology of the Ukrainian State Institute of Reproductology of the Shupyk National Healthcare University. 118 women participated in the study. Group I c

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10

Ko, Seong-Hee, and Hyun-Sook Kim. "Menopause-Associated Lipid Metabolic Disorders and Foods Beneficial for Postmenopausal Women." Nutrients 12, no. 1 (2020): 202. http://dx.doi.org/10.3390/nu12010202.

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Menopause is clinically diagnosed as a condition when a woman has not menstruated for one year. During the menopausal transition period, there is an emergence of various lipid metabolic disorders due to hormonal changes, such as decreased levels of estrogens and increased levels of circulating androgens; these may lead to the development of metabolic syndromes including cardiovascular diseases and type 2 diabetes. Dysregulation of lipid metabolism affects the body fat mass, fat-free mass, fatty acid metabolism, and various aspects of energy metabolism, such as basal metabolic ratio, adiposity,

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11

Serbeniuk, Anastasiia. "Research of Lipid Metabolism Disorders in Female Combatants." Family Medicine. European Practices, no. 3 (October 28, 2022): 12–15. https://doi.org/10.30841/2786-720X.3.2022.273906.

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<strong>The objective:</strong> to find out the peculiarities of stress-induced changes in lipid metabolism indicators in women who have experienced concussion during combat operations. Study the state and morphostructure of adipose tissue. To analyze the relationship between lipid metabolism disorders and changes in reproductive health of female combatants. <strong>Materials and methods.</strong> The research was conducted at the Department of Obstetrics, Gynecology and Reproductology of the Ukrainian State Institute of Reproductology of the Shupyk National Healthcare University. 11

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12

Florance, Ida, and Seenivasan Ramasubbu. "Current Understanding on the Role of Lipids in Macrophages and Associated Diseases." International Journal of Molecular Sciences 24, no. 1 (2022): 589. http://dx.doi.org/10.3390/ijms24010589.

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Lipid metabolism is the major intracellular mechanism driving a variety of cellular functions such as energy storage, hormone regulation and cell division. Lipids, being a primary component of the cell membrane, play a pivotal role in the survival of macrophages. Lipids are crucial for a variety of macrophage functions including phagocytosis, energy balance and ageing. However, functions of lipids in macrophages vary based on the site the macrophages are residing at. Lipid-loaded macrophages have recently been emerging as a hallmark for several diseases. This review discusses the significance

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13

Pan, Tonglin, Yuan Shi, Guo Yu, Abdureshid Mamtimin, and Wei Zhu. "Intracranial Aneurysms and Lipid Metabolism Disorders: From Molecular Mechanisms to Clinical Implications." Biomolecules 13, no. 11 (2023): 1652. http://dx.doi.org/10.3390/biom13111652.

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Many vascular diseases are linked to lipid metabolism disorders, which cause lipid accumulation and peroxidation in the vascular wall. These processes lead to degenerative changes in the vessel, such as phenotypic transformation of smooth muscle cells and dysfunction and apoptosis of endothelial cells. In intracranial aneurysms, the coexistence of lipid plaques is often observed, indicating localized lipid metabolism disorders. These disorders may impair the function of the vascular wall or result from it. We summarize the literature on the relationship between lipid metabolism disorders and i

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14

Zorkina, Yana, Valeria Ushakova, Aleksandra Ochneva, et al. "Lipids in Psychiatric Disorders: Functional and Potential Diagnostic Role as Blood Biomarkers." Metabolites 14, no. 2 (2024): 80. http://dx.doi.org/10.3390/metabo14020080.

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Lipids are a crucial component of the human brain, serving important structural and functional roles. They are involved in cell function, myelination of neuronal projections, neurotransmission, neural plasticity, energy metabolism, and neuroinflammation. Despite their significance, the role of lipids in the development of mental disorders has not been well understood. This review focused on the potential use of lipids as blood biomarkers for common mental illnesses, such as major depressive disorder, anxiety disorders, bipolar disorder, and schizophrenia. This review also discussed the impact

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Wu, Xunzhi, Zhen Chen, Yue Wu, et al. "Flazin as a Lipid Droplet Regulator against Lipid Disorders." Nutrients 14, no. 7 (2022): 1501. http://dx.doi.org/10.3390/nu14071501.

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Lipid disorders are closely related to numerous metabolic diseases, and lipid droplets (LDs) have been considered as a new target for regulating lipid metabolism. Dietary intervention and nutraceuticals provide safe and long-term beneficial effects for treating metabolic diseases. Flazin is a diet-derived bioactive constituent mainly existing in fermented foods, of which the lipid metabolism improvement function has not been studied. In this study, the effect of flazin on lipid regulation at both cell level and organelle level was investigated. Lipidomic profiling showed that flazin significan

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16

Stroyev, Ye A., E. P. Kasatkina, N. V. Dmitriyeva, and A. Yu Filimonova. "Lipid metabolism and hormonal status in patients with type I diabetes mellitus combined with subclinical hypothyroidism." Problems of Endocrinology 42, no. 4 (1996): 9–11. http://dx.doi.org/10.14341/probl12064.

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Lipid metabolism and thyroid hormonal status were examined in diabetics with type 1 condition, subclinical hypothyroidism, and a combination of both. Lipid spectrum of the blood was assessed: total cholesterol, b-lipoproteins, triglycerides, a-cholesterol, total lipids, atherogenicity index, as well as the pituitary thyrotropic hormone, triiodothyronine, and thyroxin. Hyperlipoproteinemia was detected, which was particularly typical of atherogenic lipids in not only adult patients with type I diabetes, but in children as well, paralleled by an increase of the blood level of the pituitary thyro

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17

Sarıdaş, Furkan, Filiz Mercan Sarıdaş, Canan Ersoy, and Ömer Faruk Turan. "Multiple Sclerosis and Cholesterol Metabolism." Uludağ Üniversitesi Tıp Fakültesi Dergisi 51, no. 1 (2025): 139–44. https://doi.org/10.32708/uutfd.1589812.

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Adult lipid metabolism consists of plasma lipids. Triglycerides are the most important sources of energy reserves, while phospholipids and cholesterol are key components of organelles and cell membranes. Lipids, especially cholesterol, are involved in many cellular functions. Various neurodegenerative cellular processes can develop in metabolism disorders. Neurons have significantly different lipid composition compared to other biological membranes. These differences and the role of these lipids in neuronal pathologies are still poorly understood. Studies on lipid molecules in MS date back fou

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18

Solov’eva, Veronika, Fatima Bichkaeva, Nataliya Solov’eva, and Larisa Udovenkova. "LIPID METABOLISM DISORDERS IN CHRONIC ALCOHOL INTOXICATION." Vestnik of Northern (Arctic) Federal University named after M.V.Lomonosov. Series "Medical and Biological Sciences", no. 4 (November 20, 2016): 67–72. http://dx.doi.org/10.17238/issn2308-3174.2016.4.67.

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19

Natesan, Vijayakumar, and Sung-Jin Kim. "Lipid Metabolism, Disorders and Therapeutic Drugs - Review." Biomolecules & Therapeutics 29, no. 6 (2021): 596–604. http://dx.doi.org/10.4062/biomolther.2021.122.

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20

Sych, Yu P., V. V. Fadeev, G. A. Mel'nichenko, A. L. Syrkin, and A. P. Roitman. "Disorders of lipid metabolism in subclinical hypothyroidism." Problems of Endocrinology 50, no. 3 (2004): 48–52. http://dx.doi.org/10.14341/probl11429.

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Subclinical hypothyroidism (SG) is a syndrome caused by a persistent borderline decrease in the level of thyroid hormones in the body, in which a normal level of T4 is determined in combination with a moderately elevated level of TSH. SG is the most common thyroid dysfunction.

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21

Cwik, Valerie A. "DISORDERS OF LIPID METABOLISM IN SKELETAL MUSCLE." Neurologic Clinics 18, no. 1 (2000): 167–84. http://dx.doi.org/10.1016/s0733-8619(05)70183-3.

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22

Carroll, James E. "Myopathies Caused by Disorders of Lipid Metabolism." Neurologic Clinics 6, no. 3 (1988): 563–74. http://dx.doi.org/10.1016/s0733-8619(18)30861-2.

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23

Barchiesi, Barbara J., Robert H. Eckel, and Philip P. Ellis. "The cornea and disorders of lipid metabolism." Survey of Ophthalmology 36, no. 1 (1991): 1–22. http://dx.doi.org/10.1016/0039-6257(91)90205-t.

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24

Ezhov, M. V., V. V. Kukharchuk, I. V. Sergienko, et al. "Disorders of lipid metabolism. Clinical Guidelines 2023." Russian Journal of Cardiology 28, no. 5 (2023): 5471. http://dx.doi.org/10.15829/1560-4071-2023-5471.

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The Russian Society of Cardiology (RKO)With the participation of: The National Society for the Study of Atherosclerosis (NOA), the Russian Association of Endocrinologists (RAE), the Russian Society of Cardiosomatic Rehabilitation and Secondary Prevention (RosOKR), the Russian Scientific Medical Society of Therapists (RNMOT), the Eurasian Association of Cardiologists, the Eurasian Association of Therapists (EAT), the Russian Association of Gerontologists and Geriatricians

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25

Pennisi, Elena, Matteo Garibaldi, and Giovanni Antonini. "Lipid Myopathies." Journal of Clinical Medicine 7, no. 12 (2018): 472. http://dx.doi.org/10.3390/jcm7120472.

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Disorders of lipid metabolism affect several tissues, including skeletal and cardiac muscle tissues. Lipid myopathies (LM) are rare multi-systemic diseases, which most often are due to genetic defects. Clinically, LM can have acute or chronic clinical presentation. Disease onset can occur in all ages, from early stages of life to late-adult onset, showing with a wide spectrum of clinical symptoms. Muscular involvement can be fluctuant or stable and can manifest as fatigue, exercise intolerance and muscular weakness. Muscular atrophy is rarely present. Acute muscular exacerbations, resulting in

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26

Nowowiejska, Julia, Anna Baran, and Iwona Flisiak. "Aberrations in Lipid Expression and Metabolism in Psoriasis." International Journal of Molecular Sciences 22, no. 12 (2021): 6561. http://dx.doi.org/10.3390/ijms22126561.

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Psoriasis (PSO) is a common skin disease that affects about 1%–3% of the general population. It is a great medical, social and economic burden since PSO is associated with many comorbidities, of which the most common are cardiometabolic disorders. Psoriatic patients suffer more frequently from obesity, dyslipidemia, atherosclerosis, and nonalcoholic fatty liver disease. Research shows that lipid expression and metabolism disorders are present more often in such patients. This review focuses on a variety of aberrations in lipids in the skin, blood, and adipose tissue in psoriatic patients and t

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27

Bezrodny, Svyatoslav L., Seyfaddin G. Mardanly, Alexander M. Zatevalov, Vladimir V. Pomazanov, and Emil R. Mekhtiyev. "Estimation of the state of the microbiome in the elderly with impairments of carbohydrate and lipid exchange by the method of microbiome-associated exposomics." Microbiology Independent Research Journal 9, no. 1 (2022): 9–17. https://doi.org/10.18527/2500-2236-2022-9-1-9-17.

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We performed the biochemical analysis and studied the chemical composition of blood samples in 163 people 45-90 years old with type 2 diabetes mellitus and dyslipidemia. We examined the concentrations of the following compounds in the blood samples: fatty acids, aldehydes, styrenes of microbial origin, as well as the levels of glucose, triglycerides, cholesterol, and lipids of low and high density. The chemical composition of blood was determined by gas chromatography-mass spectrometry. The concentrations of fatty acids, aldehydes (including octadecenaldehyde (18a)), and styrene

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28

Sergienko, I. V., and M. V. Ezhov. "Review and analysis of 2023 Clinical Guidelines for Lipid Metabolism Disorders." Russian Journal of Cardiology 28, no. 4S (2023): 5688. http://dx.doi.org/10.15829/1560-4071-2023-5688.

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The novelty of the 2023 National Guidelines for Lipid Metabolism Disorders is presented regarding the categorization of cardiovascular risk, target and optimal levels of blood lipids, diagnosis and therapeutic approaches to the treatment of dyslipidemia.

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29

Goldberg, Ronald B. "Lipid Disorders in Diabetes." Endocrinologist 7, no. 6 (1997): 436–42. http://dx.doi.org/10.1097/00019616-199707060-00005.

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30

Jiang, Jin, Huange Zhang, Muhammad Hussain, et al. "Novel Approaches in Glucose and Lipid Metabolism Disorder Therapy: Targeting the Gut Microbiota–Bile Acid Axis." Biology 14, no. 7 (2025): 802. https://doi.org/10.3390/biology14070802.

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Metabolic dysregulation involving glucose and lipids is closely associated with chronic diseases such as type 2 diabetes mellitus. Emerging evidence highlights the regulatory role of bile acid (BA)–gut microbiota interactions in these metabolic disorders. The gut microbiota orchestrates the biotransformation of primary BAs into bioactive secondary BAs, which function as endocrine signaling molecules by activating the nuclear farnesoid X receptor (FXR) and G protein-coupled membrane receptor (TGR5), forming a communication network essential for metabolic homeostasis. BAs also reciprocally modul

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31

You, Huimin, Xiaoyi Deng, Yan Bai, et al. "The Ameliorative Effect of COST on Diet-Induced Lipid Metabolism Disorders by Regulating Intestinal Microbiota." Marine Drugs 20, no. 7 (2022): 444. http://dx.doi.org/10.3390/md20070444.

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(1) Background: Chitosan oligosaccharides, with an average molecular weight ≤ 1000 Da (COST), is a natural marine product that has the potential to improve intestinal microflora and resist lipid metabolism disorders. (2) Methods: First, by establishing a mice model of lipid metabolism disorder induced by a high fat and high sugar diet, it is proven that COST can reduce lipid metabolism disorder, which may play a role in regulating intestinal microorganisms. Then, the key role of COST in the treatment of intestinal microorganisms is further confirmed through the method of COST-treated feces and

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32

Baba, Mirela, Mihaela Maris, Daniela Jianu, Constantin Tudor Luca, Dana Stoian, and Ioana Mozos. "The Impact of the Blood Lipids Levels on Arterial Stiffness." Journal of Cardiovascular Development and Disease 10, no. 3 (2023): 127. http://dx.doi.org/10.3390/jcdd10030127.

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Arterial stiffness is a recognized predictor of cardiovascular morbidity and death. It is an early indicator of arteriosclerosis and is influenced by numerous risk factors and biological processes. The lipid metabolism is crucial and standard blood lipids, non-conventional lipid markers and lipid ratios are associated with arterial stiffness. The objective of this review was to determine which lipid metabolism marker has a greater correlation with vascular aging and arterial stiffness. Triglycerides (TG) are the standard blood lipids that have the strongest associations with arterial stiffness

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33

Lukasiewicz, Martyna, Agata Zwara, Jacek Kowalski, Adriana Mika, and Andrzej Hellmann. "The Role of Lipid Metabolism Disorders in the Development of Thyroid Cancer." International Journal of Molecular Sciences 25, no. 13 (2024): 7129. http://dx.doi.org/10.3390/ijms25137129.

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Thyroid cancer (TC) is a neoplasm with an increasing incidence worldwide. Its etiology is complex and based on a multi-layered interplay of factors. Among these, disorders of lipid metabolism have emerged as an important area of investigation. Cancer cells are metabolically reprogrammed to promote their rapid growth, proliferation, and survival. This reprogramming is associated with significant changes at the level of lipids, mainly fatty acids (FA), as they play a critical role in maintaining cell structure, facilitating signaling pathways, and providing energy. These lipid-related changes he

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34

Ge, Xiaodong, Chang'e Wang, Huiling Chen, et al. "Luteolin cooperated with metformin hydrochloride alleviates lipid metabolism disorders and optimizes intestinal flora compositions of high-fat diet mice." Food & Function 11, no. 11 (2020): 10033–46. http://dx.doi.org/10.1039/d0fo01840f.

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35

Singh, Rajat, and Ana Maria Cuervo. "Lipophagy: Connecting Autophagy and Lipid Metabolism." International Journal of Cell Biology 2012 (2012): 1–12. http://dx.doi.org/10.1155/2012/282041.

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Lipid droplets (LDs), initially considered “inert” lipid deposits, have gained during the last decade the classification of cytosolic organelles due to their defined composition and the multiplicity of specific cellular functions in which they are involved. The classification of LD as organelles brings along the need for their regulated turnover and recent findings support the direct contribution of autophagy to this turnover through a process now described as lipophagy. This paper focuses on the characteristics of this new type of selective autophagy and the cellular consequences of the mobil

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36

Birner, Charlotte, Patricia Mester, Gerhard Liebisch, et al. "Lipid Metabolism Disorders as Diagnostic Biosignatures in Sepsis." Infectious Disease Reports 16, no. 5 (2024): 806–19. http://dx.doi.org/10.3390/idr16050062.

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Critical illness causes disturbances in lipid metabolism. Here, we investigated the levels of apolipoprotein A-IV (apoA-IV), a regulator of triglyceride and cholesterol metabolism, in human sepsis. ApoA-IV (analyzed in 156 patients with systemic inflammatory response syndrome (SIRS)/sepsis) and cholesteryl ester (CE) (analyzed in 121 of these patients) were lower in patients compared to 43 healthy controls. In contrast, triglyceride (TG) levels were elevated in patients. ApoA-IV levels in plasma of the patients did not correlate with these lipids. Patients with SIRS, sepsis or septic shock had

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37

He, Xin, Xinyu Gao, and Weidong Xie. "Research Progress in Skin Aging, Metabolism, and Related Products." International Journal of Molecular Sciences 24, no. 21 (2023): 15930. http://dx.doi.org/10.3390/ijms242115930.

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In recent years, skin aging has received increasing attention. Many factors affect skin aging, and research has shown that metabolism plays a vital role in skin aging, but there needs to be a more systematic review. This article reviews the interaction between skin metabolism and aging from the perspectives of glucose, protein, and lipid metabolism and explores relevant strategies for skin metabolism regulation. We found that skin aging affects the metabolism of three major substances, which are glucose, protein, and lipids, and the metabolism of the three major substances in the skin also aff

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38

Meng, Jin, Qiulan Lv, Aihua Sui, et al. "Hyperuricemia induces lipid disturbances by upregulating the CXCL-13 pathway." American Journal of Physiology-Gastrointestinal and Liver Physiology 322, no. 2 (2022): G256—G267. http://dx.doi.org/10.1152/ajpgi.00285.2021.

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The underlying molecular mechanism of hyperuricemia-induced lipid metabolism disorders is still unclear. The study aimed to investigate the mechanism of lipid disturbance in hyperuricemia mice model. To our knowledge, we proposed for the first time that CXCL-13 may be a key regulator of hyperuricemia and lipid metabolism disorders. These results may provide new insights for the clinical treatment of hyperuricemia.

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Ouyang, Shuhui, Zhongcheng Mo, Sha Sun, Kai Yin, and Yuncheng Lv. "Emerging role of Insig-1 in lipid metabolism and lipid disorders." Clinica Chimica Acta 508 (September 2020): 206–12. http://dx.doi.org/10.1016/j.cca.2020.05.042.

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Liang, Yaxu, Jun Qi, Dongming Yu, et al. "Ferulic Acid Alleviates Lipid and Bile Acid Metabolism Disorders by Targeting FASN and CYP7A1 in Iron Overload-Treated Mice." Antioxidants 13, no. 11 (2024): 1277. http://dx.doi.org/10.3390/antiox13111277.

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Iron overload is a common complication in various chronic liver diseases, including non-alcoholic fatty liver disease (NAFLD). Lipid and bile acid metabolism disorders are regarded as crucial hallmarks of NAFLD. However, effects of iron accumulation on lipid and bile acid metabolism are not well understood. Ferulic acid (FA) can chelate iron and regulate lipid and bile acid metabolism, but its potential to alleviate lipid and bile acid metabolism disorders caused by iron overload remains unclear. Here, in vitro experiments, iron overload induced oxidative stress, apoptosis, genomic instability

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41

Vlad, Mihaela, Daniela Amzar, Diana Bănică, et al. "Glucose and Lipid Abnormalities in Newly Diagnosed Acromegalic Patients." Romanian Journal of Diabetes Nutrition and Metabolic Diseases 22, no. 1 (2015): 47–51. http://dx.doi.org/10.1515/rjdnmd-2015-0006.

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AbstractBackground and Aims. Acromegaly is frequently associated with abnormalities of glucose and lipid metabolism. The aim of our study was to analyze the prevalence of glucose and lipid metabolism abnormalities in newly diagnosed acromegaly patients. Material and Methods. This retrospective study included 14 patients (F/M=10/4), mean age 49.5 ± 10.6 years, registered with acromegaly between January and December 2013. In all the cases the values of blood glucose (fasting and during the oral glucose tolerance test), total cholesterol and triglycerides were analyzed. The glucose disorders were

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42

Cao, Shixi, Mengqi Liu, Yao Han, et al. "Effects of Saponins on Lipid Metabolism: The Gut–Liver Axis Plays a Key Role." Nutrients 16, no. 10 (2024): 1514. http://dx.doi.org/10.3390/nu16101514.

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Unhealthy lifestyles (high-fat diet, smoking, alcohol consumption, too little exercise, etc.) in the current society are prone to cause lipid metabolism disorders affecting the health of the organism and inducing the occurrence of diseases. Saponins, as biologically active substances present in plants, have lipid-lowering, inflammation-reducing, and anti-atherosclerotic effects. Saponins are thought to be involved in the regulation of lipid metabolism in the body; it suppresses the appetite and, thus, reduces energy intake by modulating pro-opiomelanocortin/Cocaine amphetamine regulated transc

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Sabirova, Riksi Abdukadirovna, and Djakhangir Xusanovich Tursunov. "INFLUENCE OF ECDISTEN ON LIPID METABOLISM IN EXPERIMENTAL ALLOXAN DIABETES." Modern Scientific Research International Scientific Journal 1, no. 5 (2023): 28–36. https://doi.org/10.5281/zenodo.8322042.

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44

Zeng, Weibiao, Wen Zheng, Sheng Hu, et al. "Application of Lipidomics for Assessing Tissue Lipid Profiles of Patients With Squamous Cell Carcinoma." Technology in Cancer Research & Treatment 20 (January 2021): 153303382110499. http://dx.doi.org/10.1177/15330338211049903.

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Background: Lipid metabolism disorders play a key role in the pathogenesis of squamous cell carcinoma (SqCC). Herein we used lipidomics to study the tissue lipid profiles of 40 patients with SqCC. Methods: Lipidomics, based on ultrahigh-performance liquid chromatography-Q Exactive hybrid quadrupole-orbitrap high-resolution accurate mass spectrometry, was applied to identify altered lipid metabolites between tumor and adjacent noninvolved tissues (ANIT), and partial least squares-discriminant analysis model facilitated the identification of differentially abundant lipids. The area under the rec

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Chen, Lichun, Songwen Xue, Binhao Dai, and Huimin Zhao. "Effects of Coix Seed Oil on High Fat Diet-Induced Obesity and Dyslipidemia." Foods 11, no. 20 (2022): 3267. http://dx.doi.org/10.3390/foods11203267.

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Dietary intervention is becoming more popular as a way to improve lipid metabolism and reduce the prevalence of diet-related chronic disorders. We evaluated the effects of several dietary oils on body weight, fat mass, liver weight, and tumor necrosis factor in obese mice given a high-fat diet (HFD) to discover if coix seed oil (CSO) had an anti-obesity impact. As compared to other dietary fats, CSO treatment considerably lowered body weight and liver index, successfully sup-pressed total cholesterol and triglyceride content, and raised liver lipid deposition and lipid metabolism problem induc

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Zhu, Zhu, Bingxuan Hua, Zhanxian Shang, et al. "Altered Clock and Lipid Metabolism-Related Genes in Atherosclerotic Mice Kept with Abnormal Lighting Condition." BioMed Research International 2016 (2016): 1–14. http://dx.doi.org/10.1155/2016/5438589.

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Background. The risk of atherosclerosis is elevated in abnormal lipid metabolism and circadian rhythm disorder. We investigated whether abnormal lighting condition would have influenced the circadian expression of clock genes and clock-controlled lipid metabolism-related genes in ApoE-KO mice.Methods. A mouse model of atherosclerosis with circadian clock genes expression disorder was established using ApoE-KO mice (ApoE-KO LD/DL mice) by altering exposure to light. C57 BL/6J mice (C57 mice) and ApoE-KO mice (ApoE-KO mice) exposed to normal day and night and normal diet served as control mice.

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Spasić, Igor, Milan Ubavić, Zorica Šumarac, Maša Todorović, and Biljana Vučković. "Influence of lipid metabolism disorders on venous thrombosis risk." Journal of Medical Biochemistry 40, no. 3 (2021): 245–51. http://dx.doi.org/10.5937/jomb0-27106.

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Background: To investigate the influence of lipid metabolism disorders on the risk of deep vein thrombosis. Methods: A total of 200 subjects participated in the study, 100 of whom experienced DVT with or without PTE, and 100 healthy subjects representing the control group. We classified patients and controls in terms of serum concentrations of chylomicrons, LDL, IDL, VLDL, and HDL particles, as those with or without hyperlipoproteinemia and in terms of serum Lp (a) lipoprotein levels, as those with hyperLp (a) lipoproteinemia (serum Lp (a) values > 0.3 g/L) and those without hyperLp (a) lip

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Baryshnikova, N. V., V. M. L’Nyavina, Yu P. Uspenskiy, A. N. Suvorov, and E. I. Ermolenko. "Lipid metabolism correction with statins and probiotics." Experimental and Clinical Gastroenterology, no. 9 (March 6, 2025): 161–74. https://doi.org/10.31146/1682-8658-ecg-229-9-161-174.

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The gut microbiota can be regarded as a novel “metabolic organ,” involved in the regulation of metabolism. In the case of gut dysbiosis, changes in the concentration of certain bacterial metabolites can act as triggers for the development of metabolic and lipid metabolism disorders. For instance, lower levels of bacteria that produce short-chain fatty acids (SCFA), disorders of enterohepatic circulation of bile acids, elevated levels of trimethylamine (TMA)-producing gut bacteria play an important role in dyslipidemia. Undoubtedly, there are interactions between statin use and changes in the g

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van Heyningen, Charles. "Lipid metabolism: reviews of HDL and cholesterol efflux, ethanol and hepatic lipid metabolism and lipid disorders during childhood." Current Opinion in Lipidology 20, no. 1 (2009): 77–78. http://dx.doi.org/10.1097/mol.0b013e328321e5a5.

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&NA;. "Niacin ER combinations effective in lipid metabolism disorders." Inpharma Weekly &NA;, no. 1614 (2007): 2. http://dx.doi.org/10.2165/00128413-200716140-00001.

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