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Relevant bibliographies by topics / Lipid signal

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Dissertations / Theses

Academic literature on the topic 'Lipid signal'

Author: Grafiati

Published: 7 July 2024

Last updated: 7 July 2024

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Dissertations / Theses on the topic "Lipid signal"

1

Frangioudakis, Georgia St Vincent's Clinical School UNSW. "Insulin signal transduction in vivo in states of lipid-induced insulin resistance." Awarded by:University of New South Wales. St Vincent's Clinical School, 2004. http://handle.unsw.edu.au/1959.4/27419.

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Insulin resistance is the major metabolic defect in obesity and Type 2 diabetes. Increased lipid accumulation is strongly associated with insulin resistance. A significant component of insulin resistance is thought to be a reduced ability of insulin to activate the cascade of phosphorylation events that lead to the metabolic effects of this hormone. The broad aims of this thesis were to examine the effect of high-fat diets containing different fat subtypes on in vivo insulin signalling, under conditions normally used to detect whole body insulin resistance, and to compare the effects of acute

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2

Pott, Markus Philipp. "Organic hydroperoxide-induced lipid peroxidation (LPO) and signal transduction pathways in human keratinocytes." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=96545293X.

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3

FEZZA, FILOMENA. "Regulation of endocannabinoid system by lipid rafts along the neuroimmune axis." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2006. http://hdl.handle.net/2108/202611.

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L’anandamide (arachidonoiletanolammide, AEA), insieme con l’altro endocannabinoide 2arachidonoilglicerolo (2-AG), lega ed attiva i due recettori accoppiati a proteine G inibitorie, (GPCR), chiamati recettori dei cannabinoidi di tipo-1 (CB1R) e di tipo-2 (CB2R). I CB1R sono localizzati principalmente nel sistema nervoso centrale, ma sono anche espressi in tessuti periferici come le cellule immunitarie. Mentre i CB2R sono maggiormente espressi a livello periferico, ma sono anche presenti nel cervello. Quindi l’attivazione dei recettori CB1 o CB2 da parte dell’AEA e del 2-AG ha molti effetti sia

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4

Sampey, Brante P. "Studies of the adduction of hepatocellular proteins by 4-HNE in animals [sic] models of alcoholic liver disease : systematic analysis of hepatocellular Erk 1/2 modulation and dysregulation of the Erk-Elk-AP1 signal transduction pathway /." Connect to full text via ProQuest. IP filtered, 2005.

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Thesis (Ph.D. in Toxicology) -- University of Colorado, 2005.<br>Typescript. Includes bibliographical references (leaves 141-156). Free to UCDHSC affiliates. Online version available via ProQuest Digital Dissertations;

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5

Metcalfe, Maureen Grage. "Two-dimensional crystallization of archaeal signal peptide peptidases for structural studies by electron crystrallography." Thesis, Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/53984.

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The membrane proteins signal peptide peptidase, signal peptide peptidase like and presenilin are intramembrane aspartyl proteases located in the endoplasmic reticulum, plasma membrane and organelle. These membrane proteins are able to catalyze a hydrolytic reaction in a hydrophobic space. The downstream consequences of these reactions impact a variety of cellular functions such as cytokine production, inflammatory responses, embryogenesis, and immune system regulation. Additionally, the aspartyl proteases such as signal peptide peptidase and presenilin, a part of the γ-secretase complex, hydro

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6

Lautscham, Lena Astrid [Verfasser], and Ben [Akademischer Betreuer] Fabry. "Cell migration and mechanosensitive signal transduction on 2-dimensional biomembrane-mimicking lipid bilayer stacks and in confined 3-dimensional microstructures / Lena Astrid Lautscham. Gutachter: Ben Fabry." Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 2015. http://d-nb.info/1076166105/34.

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7

Casiraghi, Marina. "Functional modulation of a G protein-coupled receptor conformational landscape in a lipid bilayer." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCC138/document.

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Les récepteurs couplés aux protéines G (GPCRs en anglais) représentent la famille de récepteurs intégrales de membrane plus vaste dans la majorité des cellules eucaryotes. Ils jouent un rôle clé dans la transduction de signal, ainsi que la compréhension de leur mécanisme de signalisation représente une des questions principales dans la biologie d'aujourd'hui. Dans la caractérisation du paysage énergétique de ces récepteurs à l'échelle atomique, les structures cristallographiques publiées pendant la décennie dernière par cristallographie aux rayons X représentent la percée scientifique majeure

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8

Panakova, Daniela. "Lipoprotein particles associate with lipid-linked proteins and are required for long-range Wingless and Hedgehog signaling." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2005. http://nbn-resolving.de/urn:nbn:de:swb:14-1122025765300-27455.

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Morphogens of the Wnt and Hedgehog families are secreted signaling molecules that coordinate growth and patterning of many different tissues. Both, Wingless and Hedgehog spread across long distances in developing wing of Drosophila melanogaster. However, both proteins are covalently modified with lipid moieties. The mechanisms that allow long-range movement of such hydrophobic molecules are unclear. Like Wingles and Hedgehog, glycosylphosphatidylinositol (gpi)-linked proteins also transfer between cells with their lipid anchor intact. It has been speculated that gpi-linked proteins and lipid-l

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9

Poidevin, Mickaël. "La synthèse d'acides gras dans des cellules spécialisées agit à distance sur le processus d'activation des ovocytes chez la drosophile." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASL016.

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Une étude statistique de l'organisation mondiale de la santé a révélé qu'un adulte sur six est concerné par des problèmes d'infertilité. Ce sujet majeur de nos sociétés est complexe, multifactoriel avec une évolution à l'échelle mondiale qui est difficile à évaluer. Il est donc essentiel de mener davantage de recherche pour mieux comprendre l'évolution de l'infertilité, mais aussi les mécanismes cellulaires et moléculaires conduisant à une bonne fertilité.Fortuitement, un crible génétique des enzymes responsables de la synthèse des acides gras dans des cellules spécialisées de la drosophile a

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10

Waterstradt, Katja. "Der Einfluss des Cholesterolgehaltes der Diskmembranen des Stäbchenaußensegmentes auf die ersten Schritte der visuellen Signaltransduktion." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2009. http://dx.doi.org/10.18452/15949.

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Das Außensegment der Stäbchenzelle ist aus einem Stapel von flachen Membransäckchen, den Diskmembranen, aufgebaut. Entlang dessen existiert ein Cholesterolgradient mit 24 mol% Cholesterol in den basalen Diskmembranen und 5 mol% in den apikalen. Das Außensegment enthält alle Proteine der Signaltransduktion. Der Photorezeptor Rhodopsin ist als integrales Membranprotein in die Diskmembran eingebettet. Das G-Protein Transducin und das Effektorprotein, die Phosphodiesterase (PDE), sind periphere Proteine mit Lipidankern und somit reversibel mit der Membranoberfläche assoziiert. Um den Einfluss de

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