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Journal articles on the topic 'Lipoprotein(a)-cholesterol'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Paré, Guillaume, Michael Chong, and Pedrum Mohammadi-Shemirani. "Lipoprotein(a) Cholesterol Masquerading as Low-Density Lipoprotein Cholesterol." Journal of the American College of Cardiology 79, no. 11 (2022): 1047–49. http://dx.doi.org/10.1016/j.jacc.2022.01.014.

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2

Katsiki, Niki, Michal Vrablik, Maciej Banach, and Ioanna Gouni-Berthold. "Inclisiran, Low-Density Lipoprotein Cholesterol and Lipoprotein (a)." Pharmaceuticals 16, no. 4 (2023): 577. http://dx.doi.org/10.3390/ph16040577.

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Dyslipidemia treatment is of major importance in reducing the risk of atherosclerotic cardiovascular disease (ASCVD), which is still the most common cause of death worldwide. During the last decade, a novel lipid-lowering drug category has emerged, i.e., proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. Apart from the two available anti-PCSK9 monoclonal antibodies (alirocumab and evolocumab), other nucleic acid-based therapies that inhibit or “silence” the expression of PCSK9 are being developed. Among them, inclisiran is the first-in-class small interfering RNA (siRNA) against

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3

Bacquer, Dirk De, Delphine De Smedt, Željko Reiner, et al. "Percentage low-density lipoprotein-cholesterol response to a given statin dose is not fixed across the pre-treatment range: Real world evidence from clinical practice: Data from the ESC-EORP EUROASPIRE V Study." European Journal of Preventive Cardiology 27, no. 15 (2019): 1630–36. http://dx.doi.org/10.1177/2047487319874898.

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Aims Recent European guidelines recommend in patients with atherosclerotic cardiovascular disease to achieve a reduction of low-density lipoprotein-cholesterol of at least 50% if the baseline low-density lipoprotein-cholesterol level is between 1.8 and 3.5 mmol/L. Systematic reviews have associated a given statin/dose combination with a fixed percentage low-density lipoprotein-cholesterol response. Algorithms for detecting cases and estimating the prevalence of familial hypercholesterolaemia often rely on such fixed percentage reductions. Methods and results We used data from 915 coronary pati

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Kinpara, Kiyoko, Hiroshi Okada, Akiko Yoneyama, Minoru Okubo, and Toshio Murase. "Lipoprotein(a)-cholesterol: A significant component of serum cholesterol." Clinica Chimica Acta 412, no. 19-20 (2011): 1783–87. http://dx.doi.org/10.1016/j.cca.2011.05.036.

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5

Yeang, Calvin, Ewa Karwatowska-Prokopczuk, Fei Su, et al. "Effect of Pelacarsen on Lipoprotein(a) Cholesterol and Corrected Low-Density Lipoprotein Cholesterol." Journal of the American College of Cardiology 79, no. 11 (2022): 1035–46. http://dx.doi.org/10.1016/j.jacc.2021.12.032.

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6

Vallejo-Vaz, Antonio J., Lawrence A. Leiter, Stefano Del Prato, et al. "Triglyceride concentrations and non-high-density lipoprotein cholesterol goal attainment in the ODYSSEY phase 3 trials with alirocumab." European Journal of Preventive Cardiology 27, no. 15 (2020): 1663–74. http://dx.doi.org/10.1177/2047487320905185.

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Aims Guidelines recommend targeting non-high-density lipoprotein cholesterol to reduce cardiovascular risk. We assessed the impact of baseline triglycerides on non-high-density lipoprotein cholesterol goal attainment in 10 phase 3 trials with alirocumab versus control ( n = 4983). Methods Trials were grouped into four pools based on alirocumab dose (75–150 mg every 2 weeks), control (placebo/ezetimibe) and statin use. Baseline triglyceride quintiles were built within each pool. Non-high-density lipoprotein cholesterol goal attainment (very high risk: <100 mg/dl; moderate/high risk: <130

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7

Ahmed, Munir. "CORONARY HEART DISEASE;." Professional Medical Journal 21, no. 06 (2014): 1171–73. http://dx.doi.org/10.29309/tpmj/2014.21.06.2250.

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Objective: This study was done to find any correlation among total cholesterol, triglycerides, low density lipoprotein cholesterol and high density lipoprotein cholesterol estimated in serum of offsprings of coronary heart disease patients. Study Design: A cross sectional comparative study. Patients and Methods: Two hundred and fifty (250) subjects having parents with coronary heart disease were selected from Punjab Institute of Cardiology Lahore. The serum total cholesterol, triglycerides, low density lipoprotein cholesterol, and high density lipoprotein cholesterol were estimated. Coefficien

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8

Whyte, Martin B. "Is high-density lipoprotein a modifiable treatment target or just a biomarker for cardiovascular disease?" JRSM Cardiovascular Disease 8 (January 2019): 204800401986973. http://dx.doi.org/10.1177/2048004019869736.

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Epidemiological data strongly support the inverse association between high-density lipoprotein cholesterol concentration and cardiovascular risk. Over the last three decades, pharmaceutical strategies have been partially successful in raising high-density lipoprotein cholesterol concentration, but clinical outcomes have been disappointing. A recent therapeutic class is the cholesteryl ester transfer protein inhibitor. These drugs can increase circulating high-density lipoprotein cholesterol levels by inhibiting the exchange of cholesteryl ester from high-density lipoprotein for triacylglycerol

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Chen, Ouxiang, Qian Sun, Wenjie Liu, Ming Hong, and Sixuan Qian. "A Combination of Enteral Nutritional Support and Induction Therapy Elevates Blood Lipids, Improves Nutritional Status, and Increases Longer Overall Survival in Acute Myeloid Leukemia." Current Topics in Nutraceutical Research 22, no. 1 (2023): 74–84. http://dx.doi.org/10.37290/ctnr2641-452x.22:74-84.

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This study aimed to explore the changes in blood lipids and nutritional indexes in acute myeloid leukemia patients before and after enteral nutritional support combined with induction therapy and assess the influences of blood lipids on prognosis. The clinical data from 210 patients with initial treatment results were retrospectively analyzed. Total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol are lower in acute myeloid leukemia patients compared to normal controls, while triglyceride levels are higher. Total cholesterol and low-density lipoprotein

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10

Tambalis, Konstantinos, Demosthenes B. Panagiotakos, Stavros A. Kavouras, and Labros S. Sidossis. "Responses of Blood Lipids to Aerobic, Resistance, and Combined Aerobic with Resistance Exercise Training: A Systematic Review of Current Evidence." Angiology 60, no. 5 (2008): 614–32. http://dx.doi.org/10.1177/0003319708324927.

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This review considers the effectiveness of aerobic exercise training with different intensities (moderate and high) as well as the type of exercise (aerobic, resistance, and combined aerobic with resistance) in altering the blood lipids. We reviewed various trials via a systematic search of PubMed, published reviews, and references from original articles. We selected studies that involved aerobic and/or resistance and/or combined exercise training in healthy adults over a limit of 12 weeks and had examined the response of training to one or more of the following: triglycerides, total cholester

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11

Tesloianu, Nicolae Dan, Vlad Ghizdovat, Maricel Agop, Cristina Rusu, and Anca Cardoneanu. "On the Chameleonic Behaviour of Cholesterol through a Fractal/Multifractal Model." Computational and Mathematical Methods in Medicine 2020 (January 6, 2020): 1–11. http://dx.doi.org/10.1155/2020/6217691.

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An increasing number of studies are beginning to show that both low-density lipoprotein and high-density lipoprotein cholesterol can constitute risk factors for myocardial infarction. Such a behaviour has been called by experts in the field the “chameleonic effect” of cholesterol. In the present paper, a fractal/multifractal model for low-density lipoprotein and high-density lipoprotein cholesterol dynamics is proposed. In such a context, a fractal/multifractal tunneling effect for systems with spontaneous symmetry breaking is analyzed so that if the spontaneous symmetry breaking is assimilate

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12

Kurtul, Naciye, Sadrettin Pençe, Hasan Koçoğlu, Hülya Aksoy, and Yavuz Çapan. "Serum Lipid and Lipoproteins in Gallstone Patients." Acta Medica (Hradec Kralove, Czech Republic) 45, no. 2 (2002): 79–81. http://dx.doi.org/10.14712/18059694.2019.58.

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Serum lipid and lipoprotein concentrations were determined in a group of thirty two gallstone patients and compared to the values obtained in thirty two healthy control subjects. The serum levels of high density lipoprotein cholesterol and lipoprotein(a) in gallstone patients were found to be lower than that of the control group. Total cholesterol, triglyceride, low density lipoprotein cholesterol, apoprotein-A and apoprotein-B concentrations were observed to be higher in gallstone patients than the controls. The differences in triglyceride and low density lipoprotein cholesterol concentration

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13

Kim, Yong-Giun, Young-Rak Cho, Gyung-Min Park, et al. "High-density lipoprotein cholesterol and the risk of obstructive coronary artery disease beyond low-density lipoprotein cholesterol in non-diabetic individuals." European Journal of Preventive Cardiology 27, no. 7 (2019): 706–14. http://dx.doi.org/10.1177/2047487319844364.

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Aims The relationship between high-density lipoprotein cholesterol and the severity of coronary artery disease beyond low-density lipoprotein cholesterol, the primary target of cholesterol-lowering therapy, remains uncertain. We evaluated the association between high-density lipoprotein cholesterol and obstructive coronary artery disease using parameters of any obstructive plaque, obstructive plaque in the left main coronary artery or proximal left anterior descending artery, and obstructive plaque in multi-vessels, according to low-density lipoprotein cholesterol levels. Methods and results W

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14

Dieplinger, Hans. "Lipoprotein(a), the really bad cholesterol." Biochemical Society Transactions 27, no. 3 (1999): A91. http://dx.doi.org/10.1042/bst027a091c.

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15

Chen, Chieh. "A Narrative Review of Atherosclerosis Dyslipidemia." Archives of Clinical and Experimental Pathology 2, no. 1 (2023): 01–03. https://doi.org/10.31579/2834-8508/008.

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Most screening tests for the elevation of plasma lipids include total cholesterol, low- density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C), and triglyceride levels. It is generally accepted that elevations in levels of total cholesterol and LDL cholesterol, and a reduction in the level of HDL cholesterol place patients at a higher risk of initial and subsequent cardiac events.

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16

Goumas, Georgios S. "Is There Evidence-based Hypolipidemic Treatment with Clinical Benefit beyond Statins?" Angiology 60, no. 1 (2008): 93–98. http://dx.doi.org/10.1177/0003319708326452.

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Aggressive therapy with statins to lower the low density lipoprotein cholesterol decreases cardiovascular events. Nevertheless, administration of the highest approved statin dose only offers limited additional benefit at the expense of an increased incidence of side effects. Therefore, novel compounds that further reduce the low-density lipoprotein cholesterol and at the same time have beneficial effects on other lipid parameters when added to statin therapy are under investigation. Nicotinic acid lowers the levels of the low-density lipoprotein cholesterol and triglycerides while raising the

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17

Riaz, Haris, Safi U. Khan, Hammad Rahman, et al. "Effects of high-density lipoprotein targeting treatments on cardiovascular outcomes: A systematic review and meta-analysis." European Journal of Preventive Cardiology 26, no. 5 (2018): 533–43. http://dx.doi.org/10.1177/2047487318816495.

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Background The effects of increasing high-density lipoprotein cholesterol on cardiovascular outcomes remain uncertain. Design We conducted a meta-analysis to investigate the effects of high-density lipoprotein cholesterol modifiers (niacin, fibrates and cholesteryl ester transfer protein inhibitors) on cardiovascular outcomes. Methods Thirty-one randomized controlled trials (154,601 patients) with a follow-up of 6 months or more and a sample size of 100 or more patients were selected using MEDLINE, EMBASE and CENTRAL database (inception January 2018). Results High-density lipoprotein cholester

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18

Puja, Biswas, Md Yunus Fakir, Hossan Tareq, and Ahmed Sohel. "Detection of lipoprotein(a)- cholesterol expression in Bangladeshi adults with dyslipidemia." International Journal of Public Health Science (IJPHS) 8, no. 3 (2019): 287~293. https://doi.org/10.11591/ijphs.v8i3.20060.

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Lipoprotein(a)-cholesterol (Lp(a)-C), a low-density lipoprotein (LDL)-like particle is considered as a risk factor for cardiovascular diseases (CVDs). We aimed to investigate the association of Lp(a)-C expression with dyslipidemia among the Bangladeshi population and assess the relationship with cardiovascular risks. In this cross-sectional comparative study, a total of 180 urban males and females between ages 19-65 years were included who were enrolled in a hospital setting of Bangladesh. Participants were selected based on their total cholesterol (TC) level≥200 mg/dl, high density lipopro

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Hirowatari, Yuji, Daisuke Manita, Keiko Kamachi, and Akira Tanaka. "Effect of dietary modification by calorie restriction on cholesterol levels in lipoprotein(a) and other lipoprotein classes." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 54, no. 5 (2016): 567–76. http://dx.doi.org/10.1177/0004563216672247.

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Background Dietary habits are associated with obesity which is a risk factor for coronary heart disease. The objective is to estimate the change of lipoprotein(a) and other lipoprotein classes by calorie restriction with obesity index and Framingham risk score. Methods Sixty females (56 ± 9 years) were recruited. Their caloric intakes were reduced during the six-month period, and the calorie from fat was not more than 30%. Lipoprotein profiles were estimated at baseline and after the six-month period of calorie restriction. Cholesterol levels in six lipoprotein classes (HDL, LDL, IDL, VLDL, ch

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20

Chabanets, E. A., A. Kh Kade, A. I. Trofimenko, G. G. Kim, and V. A. Krutova. "Antiatherogenic Potential of Transcranial Electrical Stimulation in a High-Fructose/High-Fat Diet: Experimental Randomized Trial." Kuban Scientific Medical Bulletin 30, no. 3 (2023): 65–75. http://dx.doi.org/10.25207/1608-6228-2023-30-3-65-75.

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Background. Transcranial electrical stimulation is a promising method for correction of malnutrition-induced hyperlipidemia, in the absence of indications for drug hypolipidemic therapy in young and middle-aged patients with low and moderate cardiovascular risk. Objectives — to study the effect of transcranial electrical stimulation on lipid metabolism in a high-fructose/high-fat (HFHF) diet in rats.Methods. An experimental randomized trial was performed to study the effect of transcranial electrical stimulation on lipid metabolism in a high-calorie diet enriched with fructose and saturated an

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21

Yadav, Tapeshwar, M. Vijaya Bhaskar, Jayendra Bajracharya, S. S. B. Sharma, Nikky Maharjan, and Sushma Bhadeshwar. "Study of Glycated Haemoglobin and Lipid Profile in Type-2 Diabetes Mellitus." Nepal Journal of Health Sciences 2, no. 1 (2022): 17–21. http://dx.doi.org/10.3126/njhs.v2i1.47157.

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Introduction: Diabetes Mellitus is characterized by chronic hyperglycemia with disturbances of carbohydrate, fat, and protein metabolism resulting from defects in insulin secretion, insulin action, or both. Objective: To compare the biochemical parameters which included glycated hemoglobin, serum total cholesterol, triglyceride, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol of people with diabetes mellitus and matched nondiabetic controls. Methods: The cross-sectional hospital-based study was conducted among 60 diabetics and 30 nondiabetic patients. Fasting bloo

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22

Thapa, Saroj, Nirish Vaidya, Rachana Pandey, and Jyoti Shrestha Takanche. "Association of Non High Density Lipoprotein-Cholesterol and HbA1c in Type 2 Diabetes Mellitus." Journal of Nobel Medical College 12, no. 2 (2023): 30–35. http://dx.doi.org/10.3126/jonmc.v12i2.61111.

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Background: Dyslipidemia is a common issue among diabetic patients and is associated with an increased risk of cardiovascular disease. Non-High Density Lipoprotein-cholesterol has emerged as a valuable marker for assessing combined cardiovascular risk in diabetes. Measures to improve the Non-High Density Lipoprotein-cholesterol within optimal level might improve the glycemic status and decrease the cardiovascular risk. This study aims to examine the relationship between Non-High Density Lipoprotein-cholesterol and glycated hemoglobin levels in type 2 diabetic patients. Materials and Meth

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23

Muhtaseb, Najah Al, Abdul Razak Al Yousuf, and J. S. Bajaj. "Apolipoprotein A-I, A-II, B, C-II, and C-III in Children with Insulin-dependent Diabetes Mellitus." Pediatrics 89, no. 5 (1992): 936–41. http://dx.doi.org/10.1542/peds.89.5.936.

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This study was conducted to determine whether changes in the levels of plasma apolipoproteins (apo) A-I, A-II, B, C-II, and C-III, along with cholesterol and triglycerides, could provide additional information on these parameters in relation to the control of glycemia. Plasma and lipoprotein lipids and apolipoprotein levels were measured in 123 insulin-dependent diabetic childern (4- to 12-years-old), classified into good, fair, and poor diabetic control based on HbAlc and fructosamine levels, and in 62 comparable healthy controls. Total cholesterol, very low density lipoprotein cholesterol, a

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Poletto, Leonor, Stella Pezzotto, and Julio Morini. "Blood lipid associations in 18 year-old men." Revista de Saúde Pública 26, no. 5 (1992): 316–20. http://dx.doi.org/10.1590/s0034-89101992000500003.

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The association of cigarette smoking, physical activity at work, and social class with total cholesterol and with high and low density lipoprotein cholesterol were examined in a random sample of 238 males, of 18 years of age, of Rosario, Argerntina. The mean (mg/dl) total serum cholesterol of the whole sample was 174.7, the high density lipoprotein cholesterol 52.8, and the low density lipoprotein cholesterol 121.5. Black tobacco consumers, evenly distributed by social class, had higher levels of total and low density lipoprotein cholesterol. Total cholesterol was higher in the high social cla

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Sugiuchi, H., Y. Uji, H. Okabe, et al. "Direct measurement of high-density lipoprotein cholesterol in serum with polyethylene glycol-modified enzymes and sulfated alpha-cyclodextrin." Clinical Chemistry 41, no. 5 (1995): 717–23. http://dx.doi.org/10.1093/clinchem/41.5.717.

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Abstract We have developed an automated method for measuring high-density lipoprotein (HDL)-cholesterol in serum without prior separation, using polyethylene glycol (PEG)-modified enzymes and sulfated alpha-cyclodextrin. When cholesterol esterase and cholesterol oxidase enzymes were modified with PEG, they showed selective catalytic activities towards lipoprotein fractions, with the reactivity increasing in the order: low-density lipoprotein &lt; very-low-density lipoprotein approximately chylomicron &lt; HDL. In the presence of magnesium ions, alpha-cyclodextrin sulfate reduced the re

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Hopkins, K. D., E. D. Lehmann, R. G. Gosling, J. R. Parker, and P. H. Sönksen. "Biochemical Correlates of Aortic Distensibility in vivo in Normal Subjects." Clinical Science 84, no. 6 (1993): 593–97. http://dx.doi.org/10.1042/cs0840593.

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1. Non-invasive aortic compliance measurements have been used previously to assess the distensibility of the aorta in several pathological conditions associated with increased cardiovascular risk. In adult patients with familial hypercholesterolaemia and those with growth hormone deficiency, aortic compliance has been found to correlate inversely with plasma cholesterol levels and age. We set out to establish if a relationship existed between the biophysical measurement of aortic compliance and biochemical variables in normal healthy adult subjects. 2. Blood pressure-corrected aortic distensib

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Gambi, F., D. De Berardis, D. Campanella, et al. "A Retrospective Evaluation of the Inflammatory Marker C-Reactive Protein (CRP), Cholesterol and High-Density Lipoproteins in Patients with Major Depression: Preliminary Findings." European Journal of Inflammation 3, no. 3 (2005): 127–34. http://dx.doi.org/10.1177/1721727x0500300304.

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The aim of this study was to retrospectively evaluate the role of C-reactive protein, total cholesterol and high-density lipoprotein cholesterol in patients suffering from Major Depression (MD). Data of C-reactive protein, total cholesterol (TC) and high-density lipoprotein cholesterol of 37 adult outpatients (17 men, 20 women) with a DSM-IV diagnosis of MD were analyzed. Depression was measured with the 17-item Hamilton Depression Rating Scale (HAM-D) and with the Beck Depression Inventory (BDI). Suicide risk was evaluated with the Scale of Suicide Ideation (SSI). Patients with a lifetime his

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Renee Ruhaak, L., Arnoud van der Laarse, and Christa M. Cobbaert. "Apolipoprotein profiling as a personalized approach to the diagnosis and treatment of dyslipidaemia." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 56, no. 3 (2019): 338–56. http://dx.doi.org/10.1177/0004563219827620.

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An elevated low-density lipoprotein cholesterol concentration is a classical risk factor for cardiovascular disease. This has led to pharmacotherapy in patients with atherosclerotic heart disease or high heart disease risk with statins to reduce serum low-density lipoprotein cholesterol. Even in patients in whom the target levels of low-density lipoprotein cholesterol are reached, there remains a significant residual cardiovascular risk; this is due, in part, to a focus on low-density lipoprotein cholesterol alone and neglect of other important aspects of lipoprotein metabolism. A more refined

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Dawadi, Bishwa Raj, and Khilasa Pokharel. "Dyslipidemia among Pilots visiting a Tertiary Care Centre: A Descriptive Cross-sectional Study." Journal of Nepal Medical Association 61, no. 257 (2023): 47–49. http://dx.doi.org/10.31729/jnma.7968.

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Introduction: Dyslipidemia is the imbalance of various lipids in our body like cholesterol, low-density lipoprotein cholesterol, triglycerides, and high-density lipoprotein. It has been established as a major factor associated with cardiovascular disease. The aim of our study was to find out the prevalence of dyslipidemia among pilots visiting a tertiary care centre. Methods: This descriptive cross-sectional study was conducted in the family medicine department of Grande International Hospital, Dhapasi, Kathmandu from 1 May 2022 to 30 July 2022 (Reference number: 08/2022). Seventy pilots

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Kolovou, Genovefa, Olga Diakoumakou, Vana Kolovou, et al. "Microsomal triglyceride transfer protein inhibitor (lomitapide) efficacy in the treatment of patients with homozygous familial hypercholesterolaemia." European Journal of Preventive Cardiology 27, no. 2 (2019): 157–65. http://dx.doi.org/10.1177/2047487319870007.

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Aims The aim of this study was to evaluate the effect of microsomal triglyceride transfer protein inhibitor (lomitapide) in patients with homozygous familial hypercholesterolaemia. Methods and results In 12 homozygous familial hypercholesterolaemia patients treated with lipid-lowering drugs ± biweekly lipoprotein apheresis sessions (nine patients), daily lomitapide was added. The lipid profile (total cholesterol, low-density lipoprotein cholesterol, triglycerides, high-density lipoprotein cholesterol) before and after lomitapide treatment was evaluated. The follow-up period with lomitapide tre

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Okada, S., Y. Miyai, K. Ichiki, et al. "Clinofibrate Therapy Raises High-Density Lipoprotein Levels and Lowers Atherogenic Index in Diabetes Mellitus Patients." Journal of International Medical Research 17, no. 6 (1989): 521–25. http://dx.doi.org/10.1177/030006058901700604.

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The effects of clinofibrate on serum lipoprotein concentrations, lecithin cholesterol acyl transferase activity and atherogenic index were studied in 10 diabetes mellitus patients. The patients comprised five with well-controlled non-insulin-dependent diabetes, and five with poorly controlled insulin-dependent diabetes; six non-insulin-dependent diabetics acted as placebo controls. No adverse side-effects were reported and there were no significant changes in total cholesterol, triglyceride or high-density lipoprotein 3-cholesterol concentrations following 600 mg/kg clinofibrate treatment for

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Filippova, A. Yu, M. Löhr, and V. V. Kryvoshei. "Blood lipid spectrum and elastic properties of arteries in patients with chronic pancreatitis in combination with arterial hypertension." Medicni perspektivi 27, no. 1 (2022): 42–49. http://dx.doi.org/10.26641/2307-0404.2022.1.254320.

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110 patients aged 45-65 years with chronic pancreatitis were examined. The first group consisted of patients with a combined course of chronic pancreatitis with arterial hypertension; the second group - patients with chronic pancreatitis without concomitant hypertension. All patients were examined for total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and very low-density lipoprotein cholesterol. Arterial stiffness was determined by the pulse wave velocity. It was found that patients of the 1st group had significantly higher levels of t

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Filippova, A.Yu., M. Löhr, and V.V. Kryvoshei. "Blood lipid spectrum and elastic properties of arteries in patients with chronic pancreatitis in combination with arterial hypertension." Medicni perspektivi 27, no. 1 (2022): 42–49. https://doi.org/10.26641/2307-0404.2022.1.254320.

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110 patients aged 45-65 years with chronic pancreatitis were examined. The first group consisted of patients with a combined course of chronic pancreatitis with arterial hypertension; the second group - patients with chronic pancreatitis without concomitant hypertension. All patients were examined for total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and very low-density lipoprotein cholesterol. Arterial stiffness was determined by the pulse wave velocity. It was found that patients of the 1st group had significantly higher levels of t

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Craig, Wendy Y., Glenn E. Palomaki, A. Myron Johnson, and James E. Haddow. "Cigarette Smoking-Associated Changes in Blood Lipid and Lipoprotein Levels in the 8-to 19-Year-Old Age Group: A Meta-Analysis." Pediatrics 85, no. 2 (1990): 155–58. http://dx.doi.org/10.1542/peds.85.2.155.

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In this meta-analysis it was demonstrated that, when compared with nonsmokers of similar age, smokers in the 8- to 19-year-old age group have significantly higher serum levels of triglyceride (+11.8%), very-low-density lipoprotein (VLDL)-cholesterol (+12.4%) and low-density lipoprotein (LDL)-cholesterol (+4.1%) and significantly lower serum levels of high-density lipoprotein (HDL)-cholesterol (-8.5%) and total cholesterol (-3.7%). All of these smoking-associated changes are in the same direction as those found in adults, with the exception of total cholesterol levels, which are significantly i

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Nauck, M., K. Winkler, W. März, and H. Wieland. "Quantitative determination of high-, low-, and very-low-density lipoproteins and lipoprotein(a) by agarose gel electrophoresis and enzymatic cholesterol staining." Clinical Chemistry 41, no. 12 (1995): 1761–67. http://dx.doi.org/10.1093/clinchem/41.12.1761.

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Abstract Quantification of lipoprotein cholesterol was performed by enzymatic staining of cholesterol in a new agarose gel electrophoresis method that allows the separation of LDL, VLDL, HDL, and lipoprotein(a) [Lp(a)]. Lp(a) shows an electrophoretic mobility clearly distinct from VLDL and HDL. The total CVs of lipoprotein cholesterol varied between 2.7% and 3.9% for LDL, 7.8% and 23.2% for VLDL, 5.2% and 9.5% for HDL, and 6.8% and 16.4% for Lp(a). Comparison of LDL-, VLDL-, and HDL-cholesterol concentrations with the results of a combined ultracentrifugation and precipitation technique gave c

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Oriakhi, Kelly, and Patrick Uadia. "Hypolipidemic Activity of Tetracarpidium conophorum (African walnut) Seed Oil and Its Mechanism of Action." Planta Medica International Open 07, no. 04 (2020): e170-e178. http://dx.doi.org/10.1055/a-1323-0786.

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AbstractThe present study was designed to evaluate the hypolipidemic activity of Tetracarpidium conophorum oil and its mechanism(s) of action. The oil was extracted using the Soxhlet method and subjected to column chromatography/spectroscopic techniques. GC-MS analysis was performed on the oil to identify 15 constituents with 9,12,15-octadecatrienoic acid (ω-3 fatty acid or α-linolenic acid) (68%) showing the highest proportion. Isolation and purification of the oil gave three compounds, namely, β-sitosterol, stigmasterol, and stearic acid (octadecanoic acid). Thirty-five rats were used and di

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Sucato, Vincenzo, Luca Di Fazio, Cristina Madaudo, et al. "Role of Lipoprotein Ratios and Remnant Cholesterol in Patients with Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA)." Journal of Cardiovascular Development and Disease 11, no. 5 (2024): 146. http://dx.doi.org/10.3390/jcdd11050146.

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Background: Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a clinical situation characterized by evidence of acute myocardial infarction (AMI)—according to the Fourth Universal Definition of Myocardial Infarction—with normal or near-normal coronary arteries on angiographic study (stenosis < 50%). This condition is extremely variable in etiology, pathogenic mechanisms, clinical manifestations, prognosis and consequently therapeutic approach. Objective: The objective of the study was the evaluation of remnant cholesterol (RC), monocyte/high-density lipoprotein choles

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Marian, Andriana, and Iurie Dondiuc. "Lipid profile and pregnancy associated pathologies." Akademos, no. 2(69) (October 2023): 81–86. http://dx.doi.org/10.52673/18570461.23.2-69.09.

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Throughout pregnancy, maternal lipid metabolism changes substantially, all of which can be seen by analysing the lipid profile. Determination of serum total cholesterol, triglyceride, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol levels may have a predictive role in the subsequent development of pregnancyspecific pathologies such as preeclampsia, intrahepatic cholestasis of pregnancy and gestational diabetes. Also, disorders present in the lipid profile may influence the weight of the newborn at birth. Early dyslipidaemia during pregnancy, manifested by elevated

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Sloop, Gregory D., and David W. Garber. "The Effects of Low-Density Lipoprotein and High-Density Lipoprotein on Blood Viscosity Correlate with their Association with Risk of Atherosclerosis in Humans." Clinical Science 92, no. 5 (1997): 473–79. http://dx.doi.org/10.1042/cs0920473.

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1. Increased blood or plasma viscosity has been observed in almost all conditions associated with accelerated atherosclerosis. Cognizant of the enlarging body of evidence implicating increased viscosity in atherogenesis, we hypothesize that the effects of low-density lipoprotein and high-density lipoprotein on blood viscosity correlate with their association with risk of atherosclerosis. 2. Blood viscometry was performed on samples from 28 healthy, non-fasting adult volunteers using a capillary viscometer. Data were correlated with haematocrit, fibrinogen, serum viscosity, total cholesterol, h

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Herdt, Thomas H., and Jennifer C. Smith. "Blood-Lipid and Lactation-Stage Factors Affecting Serum Vitamin E Concentrations and Vitamin E Cholesterol Ratios in Dairy Cattle." Journal of Veterinary Diagnostic Investigation 8, no. 2 (1996): 228–32. http://dx.doi.org/10.1177/104063879600800213.

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The distribution of cholesterol and vitamin E among the various lipoprotein density fractions in bovine blood was measured. The percentage of total plasma vitamin E and cholesterol in the various lipoprotein fractions was very-low-density lipoprotein, 2% and 2%, respectively; low-density lipoprotein, 17% and 22%, respectively; and high-density lipoprotein, 77% and 72%, respectively. Only 3% of plasma vitamin E was not associated with the lipoproteins. Vitamin E cholesterol ratios were not significantly different among lipoprotein fractions ( P = 0.3). These results indicate that vitamin E and

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Tulla, Samatha, and Syeda Ayesha Siddiqua. "Study of lipids and lipoprotein levels in uncomplicated diabetes mellitus patients attending Shadan hospital." International Journal of Research in Medical Sciences 9, no. 11 (2021): 3370. http://dx.doi.org/10.18203/2320-6012.ijrms20214419.

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Background: Lipid and lipoprotein levels are interrelated with diabetes mellitus. Abnormalities in the levels of total cholesterol (TC) or triglycerides (TAG) or low-density lipoprotein (LDL) cholesterol or very-low-density lipoprotein (VLDL) cholesterol or high-density lipoprotein (HDL) cholesterol or lipoprotein (a) [Lp (a)] is traditionally named as dyslipidemia. Diabetes mellitus has been known to be associated with lipid disorders and cardiovascular diseases. In patients with diabetes mellitus, dyslipidemia occurs earlier in life, leading to increased morbidity and mortality rates. The st

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Friedlander, Y., J. D. Kark, and Y. Stein. "Variability of plasma lipids and lipoproteins: the Jerusalem Lipid Research Clinic Study." Clinical Chemistry 31, no. 7 (1985): 1121–26. http://dx.doi.org/10.1093/clinchem/31.7.1121.

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Abstract We examined the variability of lipid and lipoprotein concentrations in plasma from a population sample from the Jerusalem Lipid Research Clinic study. Coefficients of variation of about 8% for plasma cholesterol, 11% to 15% for low- and high-density-lipoprotein cholesterol, and about 30% for triglyceride were reported, both for 17-year-olds and adults examined twice, with a median period of two months between measurements. Stability was similar in a subsample of adults who had an additional measurement a median of 28 months later. Within-assay analytical variation (CV) was 1.9-2.0% fo

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Massé, Jacques. "Effect of interleukin-3 on lipoprotein(a) and lipoprotein cholesterol levels." American Journal of Cardiology 76, no. 10 (1995): 747. http://dx.doi.org/10.1016/s0002-9149(99)80219-7.

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Tindall, Alyssa M., Penny M. Kris-Etherton, and Kristina S. Petersen. "Replacing Saturated Fats with Unsaturated Fats from Walnuts or Vegetable Oils Lowers Atherogenic Lipoprotein Classes Without Increasing Lipoprotein(a)." Journal of Nutrition 150, no. 4 (2020): 818–25. http://dx.doi.org/10.1093/jn/nxz313.

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ABSTRACT Background Walnuts have established lipid-/lipoprotein-lowering properties; however, their effect on lipoprotein subclasses has not been investigated. Furthermore, the mechanisms by which walnuts improve lipid/lipoprotein concentrations are incompletely understood. Objectives We aimed to examine, as exploratory outcomes of this trial, the effect of replacing SFAs with unsaturated fats from walnuts or vegetable oils on lipoprotein subclasses, cholesterol efflux, and proprotein convertase subtilisin/kexin type 9 (PCSK9). Methods A randomized, crossover, controlled-feeding study was cond

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Kolovou, Genovefa D. "Editorial: Lipoprotein (a), More than Just Cholesterol?" Current Medicinal Chemistry 24, no. 10 (2017): 952–56. http://dx.doi.org/10.2174/092986732410170526175719.

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Ghilain, J.-M., A. Parfonry, V. Kozyreff, and F. R. Heller. "LIPOPROTEIN(a), CHOLESTEROL, AND CORONARY HEART DISEASES." Lancet 332, no. 8617 (1988): 963. http://dx.doi.org/10.1016/s0140-6736(88)92630-x.

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Yeang, Calvin, Peter Willeit, and Sotirios Tsimikas. "The interconnection between lipoprotein(a), lipoprotein(a) cholesterol and true LDL-cholesterol in the diagnosis of familial hypercholesterolemia." Current Opinion in Lipidology 31, no. 6 (2020): 305–12. http://dx.doi.org/10.1097/mol.0000000000000713.

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Parhofer, Klaus G., P. Hugh R. Barrett, and Peter Schwandt. "Atorvastatin Improves Postprandial Lipoprotein Metabolism in Normolipidemic Subjects1." Journal of Clinical Endocrinology & Metabolism 85, no. 11 (2000): 4224–30. http://dx.doi.org/10.1210/jcem.85.11.6978.

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Atorvastatin is a potent HMG-CoA reductase inhibitor that decreases low-density lipoprotein (LDL) cholesterol and fasting triglyceride concentrations. Because of the positive association between elevated postprandial lipoproteins and atherosclerosis, we investigated the effect of atorvastatin on postprandial lipoprotein metabolism. The effect of 4 weeks of atorvastatin therapy (10 mg/day) was evaluated in 10 normolipidemic men (30 ± 2 yr; body mass index, 22 ± 3 kg/m2; cholesterol, 4.84 ± 0.54 mmol/L; triglyceride, 1.47 ± 0.50 mmol/L; high-density lipoprotein cholesterol, 1.17 ± 0.18 mmol/L; L

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Bahls, Martin, Matthias W. Lorenz, Marcus Dörr, et al. "Progression of conventional cardiovascular risk factors and vascular disease risk in individuals: insights from the PROG-IMT consortium." European Journal of Preventive Cardiology 27, no. 3 (2019): 234–43. http://dx.doi.org/10.1177/2047487319877078.

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Aims Averaged measurements, but not the progression based on multiple assessments of carotid intima-media thickness, (cIMT) are predictive of cardiovascular disease (CVD) events in individuals. Whether this is true for conventional risk factors is unclear. Methods and results An individual participant meta-analysis was used to associate the annualised progression of systolic blood pressure, total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol with future cardiovascular disease risk in 13 prospective cohort studies of the PROG-IMT collaboration ( n = 3

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Dakheel Hussein Hadree. "Protective role of Pomegranate (punica granatam L.) juice in inhibition liver toxicity induced by amikacin in white Newzealad Rabbits." Tikrit Journal of Pure Science 20, no. 2 (2023): 78–83. http://dx.doi.org/10.25130/tjps.v20i2.1163.

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In present study, aminoglycosides as amikacin, was proved to induce alterations in the liver of experimental animals. The aim present study is to investigate the effect of amikacin on rabbit liver which is commonly used in infections resistant to other antibiotics and study treated and protective effect of Pomegranate juice(Punica granatum L.), which antibiotic inhibit & decrease liver toxic formed by amikacin in males and females white rabbits by measuring some of the criteria for biochemical variations, such as, blood serum cholesterol (Ch), triglyceride concentration (TG), blood serum h

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