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Relevant bibliographies by topics / Liposphere

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Academic literature on the topic 'Liposphere'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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Journal articles on the topic "Liposphere"

1

Shubhra Rai, Gopal Rai, and Ashish Budhrani. "Development, Optimisation and Evaluation of Ketoprofen Lipospheres." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 1853–63. http://dx.doi.org/10.26452/ijrps.v11ispl4.4389.

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Lipospheres represent a novel type of fat-based encapsulation system produced for the topical drug delivery of bioactive compounds. The goal of this research work was to develop lipospheres, including ketoprofen applied for topical skin drug delivery. Ketoprofen lipospheres were formulated by melt emulsification method using stearic acid and Phospholipon® 90G. The lipospheres were analysed in terms of particle size and morphology, entrapment efficiency, Differential scanning calorimetry, In-vitro drug release, In-vivo (Anti-inflammatory activity). Outcomes of research revealed that particle si

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2

Zaki, Randa Mohammed, Mohammed F. Aldawsari, Manal A. Alossaimi, et al. "Brain Targeting of Quetiapine Fumarate via Intranasal Delivery of Loaded Lipospheres: Fabrication, In-Vitro Evaluation, Optimization, and In-Vivo Assessment." Pharmaceuticals 15, no. 9 (2022): 1083. http://dx.doi.org/10.3390/ph15091083.

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A liposphere system for intranasal delivery of quetiapine fumarate (QTF) was created to assess the potential for enhanced drug delivery. We investigated the effects of particle size, entrapment effectiveness, poly dispersibility index, and pluronic incorporation percentage on these variables. The optimal formula was examined using a TEM, and investigations into DSC, XRD, and FTIR were made. Optimized liposphere formulation in vitro dissolution investigation with a mean diameter of 294.4 ± 18.2 nm revealed about 80% drug release in 6 h. The intranasal injection of QTF-loaded lipospheres showed

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3

Saini, Sarika, and Aman Mittal. "Formulation and in-vitro evaluation of Glipizide (Anti diabetic drug) Liposphere." Journal of Drug Delivery and Therapeutics 8, no. 6-s (2018): 116–19. http://dx.doi.org/10.22270/jddt.v8i6-s.2096.

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Objective- The aim of the present study was to formulate and in- vitro study of glipizide liposphere by using melt dispersion technique. Methods- Glipizide Liposphere system composed of paraffin wax, Stearic acid as lipid phase and sodium lauryl sulphate as surfactant. Glipizide lipospheres were prepared by using melt dispersion technique. Formulation of Glipizide was evaluated such as organoleptic properties, particle size, drug content, entrapment efficiency in-vitro study and stability of the lipospheres. Result- The formation of glipizide lipospheres by using melt dispersion te

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Tanwar, Rajni, Arshdeep Singh Brar, and Puja Gulati. "Norfloxacin-Loaded Lipospheres: A Novel Lipid-Based Approach for Enhanced Solubility, Stability and Bioavailability." Journal of Neonatal Surgery 14, no. 7S (2025): 618–32. https://doi.org/10.52783/jns.v14.2462.

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Norfloxacin, a second-generation fluoroquinolone exhibits potent antibacterial activity but suffers from poor oral bioavailability due to limited solubility, permeability and extensive first-pass metabolism. Liposphere-based drug delivery systems offer a promising approach to overcoming these limitations by encapsulating norfloxacin in lipid matrices enhancing its solubility, stability and controlled release. This review explores the formulation strategies, characterization and evaluation of norfloxacin-loaded lipospheres. Various preparation techniques including solvent evaporation, melt disp

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Kajal, Bilgaiyan* Kaushelendra Mishra Kajal Sharma Parul Mehta. "Development And Characterization Of Liposphere Of Antidiabetic Drug Nateglinide For Enhance Bioavailability." International Journal in Pharmaceutical Sciences 2, no. 7 (2024): 177–86. https://doi.org/10.5281/zenodo.12617074.

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The aim of this study was to develop and characterize lipospheres of the antidiabetic drug. Nateglinide to enhance its bioavailability. Nateglinide, a poorly water-soluble drug, poses challenges in achieving optimal therapeutic effects due to its limited solubility and bioavailability. Lipospheres, lipid-based drug delivery systems, offer a promising approach to overcome these challenges by enhancing drug solubility and bioavailability. In this research, lipospheres of Nateglinide were prepared using a solvent evaporation method with various lipids and surfactants. The formulated lipospheres w

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6

Momoh, MA, FC Kenechukwu, MS Gwarzo, and PF Builders. "Formulation and Evaluation of Ibuprofen Loaded Lipospheres for Effective Oral Drug Delivery." Dhaka University Journal of Pharmaceutical Sciences 14, no. 1 (2015): 17–27. http://dx.doi.org/10.3329/dujps.v14i1.23730.

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Ibuprofen (IBU) is an anti-inflammatory drug characterized by low solubility and bioavailabilty. This study was to develop IBU-liposphere and investigated for in vitro and in vivo performance. IBU free base was incorporated into lipospheres based on micronized beeswax and Phospholipon® 90H in the ratio of (1:3), via hot emulsification. IBU-loaded lipospheres were characterized based on morphology, encapsulation efficiency (EE%), and in vitro drug release. Analgesic, anti-inflammatory activities and the pharmacokinetics were similarly evaluated. Minimum and maximum encapsulation efficiency (EE%

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7

Ramesh Ahirwar, Ashish Chaurasia, Pooja Adhikari, and Muskan Kankane. "Formulation and In vitro characterization of the sustained release liposphere containing flavonoid Naringin." World Journal of Biology Pharmacy and Health Sciences 15, no. 3 (2023): 166–77. http://dx.doi.org/10.30574/wjbphs.2023.15.3.0396.

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The purpose of the study was to formulate sustained release liposphere of naringin. The aim was to increase the solubility and improve the loading of drug as well as drug rlease. The liposphere was formulated using melt dispersion method and then sonicated to achieve the desired size. The formulated liposphere were then evaluated for drug loading, entrapment of drug, solubility and In vitro drug release studies. The highest percentages of drug loading and drug entrapment are seen observed to be 16.233±0.208% and 97.395±0.189%. The manufactured liposphere of naringin showed sustained release to

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Ramesh, Ahirwar, Chaurasia Ashish, Adhikari Pooja, and Kankane Muskan. "Formulation and In vitro characterization of the sustained release liposphere containing flavonoid Naringin." World Journal of Biology Pharmacy and Health Sciences 15, no. 3 (2023): 166–77. https://doi.org/10.5281/zenodo.10714457.

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The purpose of the study was to formulate sustained release liposphere of naringin. The aim was to increase the solubility and improve the loading of drug as well as drug rlease. The liposphere was formulated using melt dispersion method and then sonicated to achieve the desired size. The formulated liposphere were then evaluated for drug loading, entrapment of drug, solubility and <em>In vitro</em> drug release studies. The highest percentages of drug loading and drug entrapment are seen observed to be 16.233±0.208% and 97.395±0.189%. The manufactured liposphere of naringin

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9

Neeraj, Kumar Rathour* Ajay Singh Saurabh Mishra. "A Review on Orally Administration of Lipospheres for Enhancement of Solubility." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 1634–52. https://doi.org/10.5281/zenodo.15044972.

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Lipospheres are lipid-based drug delivery systems designed to enhance the solubility and bioavailability of poorly water-soluble drugs. These colloidal carriers consist of a solid hydrophobic lipid core stabilized by a phospholipid layer, offering advantages such as high drug entrapment, controlled release, and improved drug stability. Lipospheres are particularly beneficial for the oral administration of Biopharmaceutics Classification System (BCS) Class II drugs, including cyclosporine A, by improving their dissolution rate and gastrointestinal absorption. Various preparation techniques, inc

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Avramoff, Avi, Wahid Khan, Aviva Ezra, Anna Elgart, Amnon Hoffman, and Abraham J. Domb. "Cyclosporin pro-dispersion liposphere formulation." Journal of Controlled Release 160, no. 2 (2012): 401–6. http://dx.doi.org/10.1016/j.jconrel.2011.12.016.

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Books on the topic "Liposphere"

1

Claudio, Nastruzzi, ed. Lipospheres in drug targets and delivery: Approaches, methods, and applications. CRC Press, 2005.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. CRC, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2005.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Book chapters on the topic "Liposphere"

1

Vergara-Irigaray, Nuria, Michèle Riesen, Gianluca Piazza, et al. "Lipospheres." In Encyclopedia of Nanotechnology. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-90-481-9751-4_100349.

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2

Lanjhiyana, S. K., Gopal Bihari, Sanmati Kumar Jain, Sweety Lanjhiyana, and Sakshi Gupta. "AN OVERVIEW ON NOVEL LIPOSPHERE DRUG DELIVERY SYSTEM: CURRENT SCENARIO." In Futuristic Trends in Chemical Material Sciences & Nano Technology Volume 3 Book 12. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3becs12p2ch13.

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Topical delivery offers a non-invasive and simple alternative to the traditional delivery method for both systemic and topical drug administration. The biggest obstacle to successfully delivering medication molecules to the deeper layers of skin for systemic absorption is the skin's significant imperviousness. Numerous approaches have been explored to enhance the efficacy of drug delivery across the epidermal barrier. Lipid-based colloidal carriers have garnered significant attention due to their ability to interact with the skin's lipid-rich composition, facilitating transdermal drug administ

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Lanjhiyana, S. K., Gopal Bihari, Sanmati Kumar Jain, Sweety Lanjhiyana, and Sakshi Gupta. "POLYMERIC LIPOSPHERE DRUG DELIVERY SYSTEM: REVIEW ON PREPARATION METHODS AND DISEASE MANAGEMENT." In Futuristic Trends in Chemical Material Sciences & Nano Technology Volume 3 Book 12. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3becs12p2ch9.

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The biggest and most accessible organ of the body is the skin. Topical medication delivery has become more and more popular among people as the prevalence of dermatological problems, desire for drug targeting, and patient compliance have all grown. The stratum corneum, the top layer of the epidermis, blocks the penetration of most pharmaceuticals, making drug administration over the skin a difficulty for researchers. To administer the medications topically, a variety of techniques have been utilised, including the use of chemical permeation enhancers and physical techniques including sonophore

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4

"Lipospheres." In Encyclopedia of Nanotechnology. Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-017-9780-1_100475.

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5

"Lipospheres for Vaccine Delivery." In Lipospheres in Drug Targets and Delivery. CRC Press, 2004. http://dx.doi.org/10.1201/9780203505281-9.

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Mizrahi, Boaz, Abraham Domb, and Aviva Ezra. "Lipospheres for Vaccine Delivery." In Lipospheres in Drug Targets and Delivery. CRC Press, 2004. http://dx.doi.org/10.1201/9780203505281.ch5.

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7

Amselem, Shimon, Carl R. Alving, and Abraham J. Domb. "Lipospheres for Vaccine Delivery." In Microparticulate Systems for the Delivery of Proteins and Vaccines. CRC Press, 2020. http://dx.doi.org/10.1201/9781003067542-5.

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8

"Lipospheres for Controlled Delivery of Substances." In Microencapsulation. CRC Press, 2005. http://dx.doi.org/10.1201/9781420027990-14.

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9

Domb, Abraham. "Lipospheres for Controlled Delivery of Substances." In Drugs and the Pharmaceutical Sciences. Informa Healthcare, 2005. http://dx.doi.org/10.1201/9781420027990.ch10.

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10

"Production of Lipospheres for Bioactive Compound Delivery." In Lipospheres in Drug Targets and Delivery. CRC Press, 2004. http://dx.doi.org/10.1201/9780203505281-6.

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Conference papers on the topic "Liposphere"

1

Hettiarachchi, Kanaka, Abraham P. Lee, Steven G. Feingold, Paul S. Sheeran, and Paul A. Dayton. "Ultrasonic analysis of precision-engineered acoustically active lipospheres produced by microfluidic." In 2009 IEEE International Ultrasonics Symposium. IEEE, 2009. http://dx.doi.org/10.1109/ultsym.2009.5441565.

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