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Relevant bibliographies by topics / Lipospheres

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Academic literature on the topic 'Lipospheres'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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Journal articles on the topic "Lipospheres"

1

Shubhra Rai, Gopal Rai, and Ashish Budhrani. "Development, Optimisation and Evaluation of Ketoprofen Lipospheres." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 1853–63. http://dx.doi.org/10.26452/ijrps.v11ispl4.4389.

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Lipospheres represent a novel type of fat-based encapsulation system produced for the topical drug delivery of bioactive compounds. The goal of this research work was to develop lipospheres, including ketoprofen applied for topical skin drug delivery. Ketoprofen lipospheres were formulated by melt emulsification method using stearic acid and Phospholipon® 90G. The lipospheres were analysed in terms of particle size and morphology, entrapment efficiency, Differential scanning calorimetry, In-vitro drug release, In-vivo (Anti-inflammatory activity). Outcomes of research revealed that particle si

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2

Saini, Sarika, and Aman Mittal. "Formulation and in-vitro evaluation of Glipizide (Anti diabetic drug) Liposphere." Journal of Drug Delivery and Therapeutics 8, no. 6-s (2018): 116–19. http://dx.doi.org/10.22270/jddt.v8i6-s.2096.

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Objective- The aim of the present study was to formulate and in- vitro study of glipizide liposphere by using melt dispersion technique. Methods- Glipizide Liposphere system composed of paraffin wax, Stearic acid as lipid phase and sodium lauryl sulphate as surfactant. Glipizide lipospheres were prepared by using melt dispersion technique. Formulation of Glipizide was evaluated such as organoleptic properties, particle size, drug content, entrapment efficiency in-vitro study and stability of the lipospheres. Result- The formation of glipizide lipospheres by using melt dispersion te

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3

Tanwar, Rajni, Arshdeep Singh Brar, and Puja Gulati. "Norfloxacin-Loaded Lipospheres: A Novel Lipid-Based Approach for Enhanced Solubility, Stability and Bioavailability." Journal of Neonatal Surgery 14, no. 7S (2025): 618–32. https://doi.org/10.52783/jns.v14.2462.

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Norfloxacin, a second-generation fluoroquinolone exhibits potent antibacterial activity but suffers from poor oral bioavailability due to limited solubility, permeability and extensive first-pass metabolism. Liposphere-based drug delivery systems offer a promising approach to overcoming these limitations by encapsulating norfloxacin in lipid matrices enhancing its solubility, stability and controlled release. This review explores the formulation strategies, characterization and evaluation of norfloxacin-loaded lipospheres. Various preparation techniques including solvent evaporation, melt disp

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4

Momoh, MA, FC Kenechukwu, MS Gwarzo, and PF Builders. "Formulation and Evaluation of Ibuprofen Loaded Lipospheres for Effective Oral Drug Delivery." Dhaka University Journal of Pharmaceutical Sciences 14, no. 1 (2015): 17–27. http://dx.doi.org/10.3329/dujps.v14i1.23730.

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Ibuprofen (IBU) is an anti-inflammatory drug characterized by low solubility and bioavailabilty. This study was to develop IBU-liposphere and investigated for in vitro and in vivo performance. IBU free base was incorporated into lipospheres based on micronized beeswax and Phospholipon® 90H in the ratio of (1:3), via hot emulsification. IBU-loaded lipospheres were characterized based on morphology, encapsulation efficiency (EE%), and in vitro drug release. Analgesic, anti-inflammatory activities and the pharmacokinetics were similarly evaluated. Minimum and maximum encapsulation efficiency (EE%

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Kajal, Bilgaiyan* Kaushelendra Mishra Kajal Sharma Parul Mehta. "Development And Characterization Of Liposphere Of Antidiabetic Drug Nateglinide For Enhance Bioavailability." International Journal in Pharmaceutical Sciences 2, no. 7 (2024): 177–86. https://doi.org/10.5281/zenodo.12617074.

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The aim of this study was to develop and characterize lipospheres of the antidiabetic drug. Nateglinide to enhance its bioavailability. Nateglinide, a poorly water-soluble drug, poses challenges in achieving optimal therapeutic effects due to its limited solubility and bioavailability. Lipospheres, lipid-based drug delivery systems, offer a promising approach to overcome these challenges by enhancing drug solubility and bioavailability. In this research, lipospheres of Nateglinide were prepared using a solvent evaporation method with various lipids and surfactants. The formulated lipospheres w

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6

Neeraj, Kumar Rathour* Ajay Singh Saurabh Mishra. "A Review on Orally Administration of Lipospheres for Enhancement of Solubility." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 1634–52. https://doi.org/10.5281/zenodo.15044972.

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Lipospheres are lipid-based drug delivery systems designed to enhance the solubility and bioavailability of poorly water-soluble drugs. These colloidal carriers consist of a solid hydrophobic lipid core stabilized by a phospholipid layer, offering advantages such as high drug entrapment, controlled release, and improved drug stability. Lipospheres are particularly beneficial for the oral administration of Biopharmaceutics Classification System (BCS) Class II drugs, including cyclosporine A, by improving their dissolution rate and gastrointestinal absorption. Various preparation techniques, inc

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7

Zaki, Randa Mohammed, Mohammed F. Aldawsari, Manal A. Alossaimi, et al. "Brain Targeting of Quetiapine Fumarate via Intranasal Delivery of Loaded Lipospheres: Fabrication, In-Vitro Evaluation, Optimization, and In-Vivo Assessment." Pharmaceuticals 15, no. 9 (2022): 1083. http://dx.doi.org/10.3390/ph15091083.

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A liposphere system for intranasal delivery of quetiapine fumarate (QTF) was created to assess the potential for enhanced drug delivery. We investigated the effects of particle size, entrapment effectiveness, poly dispersibility index, and pluronic incorporation percentage on these variables. The optimal formula was examined using a TEM, and investigations into DSC, XRD, and FTIR were made. Optimized liposphere formulation in vitro dissolution investigation with a mean diameter of 294.4 ± 18.2 nm revealed about 80% drug release in 6 h. The intranasal injection of QTF-loaded lipospheres showed

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8

Nnamani, Petra Obioma, Edith Obioma Diovu, Ikechukwu Emmanuel Peter, et al. "Anti-Inflammatory and Antinociceptive Activity of Herbal Lipospheres of Pentaclethra macrophylla (Fabaceae) Stem Bark Extract." Processes 11, no. 9 (2023): 2557. http://dx.doi.org/10.3390/pr11092557.

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Purpose: Inflammation of various degrees is common among humans. There are associated side effects with orthodox delivery systems and anti-inflammatory agents; hence, the study investigated the characteristics of herbal lipospheres and the anti-inflammatory potency of the lipospheres formulated from Pentaclethra macrophylla with the view to having a drug with a better delivery system and lesser side effects. Methods: Herbal lipospheres were formulated using solidified reverse micellar solutions (SRMS) of P90H and goat fat and characterized for particle size and morphology, pH time dependent an

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9

Kumar, Anil, Umesh K. Jain, and Ajay Patel. "Formulation Development and Evaluation of Liposphere of Poor Water Soluble Drug for Hyperlipidemia." Journal of Drug Delivery and Therapeutics 11, no. 2 (2021): 23–30. http://dx.doi.org/10.22270/jddt.v11i2.4578.

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Lipospheres offer a new approach to improve an aqueous solubility of BCS class-II drugs. Simvastatin is a third generation fibric acid derivative belonging to this class, employed clinically as a hypolipidemic agent to lessen the risk caused by atherosclerosis. An attempt was made to improve aqueous solubility of Simvastatin by aid of stearic acid and Paraffin oil. The factorial batches of the Simvastatin lipospheres were formulated by melt dispersion technique using 32 factorial design with variables X1- concentration of stearic acid and X2- concentration of paraffin oil and responses Y1 - %

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Elgart, Anna, Irina Cherniakov, Yanir Aldouby, Abraham J. Domb, and Amnon Hoffman. "Lipospheres and pro-nano lipospheres for delivery of poorly water soluble compounds." Chemistry and Physics of Lipids 165, no. 4 (2012): 438–53. http://dx.doi.org/10.1016/j.chemphyslip.2012.01.007.

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Books on the topic "Lipospheres"

1

Claudio, Nastruzzi, ed. Lipospheres in drug targets and delivery: Approaches, methods, and applications. CRC Press, 2005.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. CRC, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2005.

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Nastruzzi, Claudio. Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications. Taylor & Francis Group, 2004.

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Book chapters on the topic "Lipospheres"

1

Vergara-Irigaray, Nuria, Michèle Riesen, Gianluca Piazza, et al. "Lipospheres." In Encyclopedia of Nanotechnology. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-90-481-9751-4_100349.

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"Lipospheres." In Encyclopedia of Nanotechnology. Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-017-9780-1_100475.

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"Lipospheres for Vaccine Delivery." In Lipospheres in Drug Targets and Delivery. CRC Press, 2004. http://dx.doi.org/10.1201/9780203505281-9.

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Mizrahi, Boaz, Abraham Domb, and Aviva Ezra. "Lipospheres for Vaccine Delivery." In Lipospheres in Drug Targets and Delivery. CRC Press, 2004. http://dx.doi.org/10.1201/9780203505281.ch5.

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5

Amselem, Shimon, Carl R. Alving, and Abraham J. Domb. "Lipospheres for Vaccine Delivery." In Microparticulate Systems for the Delivery of Proteins and Vaccines. CRC Press, 2020. http://dx.doi.org/10.1201/9781003067542-5.

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6

"Lipospheres for Controlled Delivery of Substances." In Microencapsulation. CRC Press, 2005. http://dx.doi.org/10.1201/9781420027990-14.

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Domb, Abraham. "Lipospheres for Controlled Delivery of Substances." In Drugs and the Pharmaceutical Sciences. Informa Healthcare, 2005. http://dx.doi.org/10.1201/9781420027990.ch10.

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8

"Production of Lipospheres for Bioactive Compound Delivery." In Lipospheres in Drug Targets and Delivery. CRC Press, 2004. http://dx.doi.org/10.1201/9780203505281-6.

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9

Cortesi, Rita, Claudio Nastruzzi, and Elisabetta Esposito. "Production of Lipospheres for Bioactive Compound Delivery." In Lipospheres in Drug Targets and Delivery. CRC Press, 2004. http://dx.doi.org/10.1201/9780203505281.ch2.

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10

"Solid Lipid Nanoparticles: Interaction with Cells, Cytokine Production, and Enzymatic Degradation." In Lipospheres in Drug Targets and Delivery. CRC Press, 2004. http://dx.doi.org/10.1201/9780203505281-10.

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Conference papers on the topic "Lipospheres"

1

Hettiarachchi, Kanaka, Abraham P. Lee, Steven G. Feingold, Paul S. Sheeran, and Paul A. Dayton. "Ultrasonic analysis of precision-engineered acoustically active lipospheres produced by microfluidic." In 2009 IEEE International Ultrasonics Symposium. IEEE, 2009. http://dx.doi.org/10.1109/ultsym.2009.5441565.

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