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Journal articles on the topic 'Liquid biopsy'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Singh, Pratibha, Meenakshi Gothwal, and Garima Yadav. "Liquid Biopsy in Ovarian Cancer." Indian Journal of Obstetrics and Gynecology 6, no. 4 (2018): 427–31. http://dx.doi.org/10.21088/ijog.2321.1636.6418.16.

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2

Jain, Amit Kumar, Guruprasad Bhat, Vineet Govinda Gupta, and Hari Goyal. "Liquid Biopsy." Indian Journal of Medical and Paediatric Oncology 42, no. 01 (2021): 077–79. http://dx.doi.org/10.1055/s-0041-1729434.

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3

Goodwin, Peter M. "Liquid Biopsy." Oncology Times 38, no. 13 (2016): 40. http://dx.doi.org/10.1097/01.cot.0000489521.34002.61.

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4

Siddiqua, Umme Iffat. "Liquid Biopsy." KYAMC Journal 10, no. 1 (2019): 1. http://dx.doi.org/10.3329/kyamcj.v10i1.41473.

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5

Gingras, Isabelle, Roberto Salgado, and Michail Ignatiadis. "Liquid biopsy." Current Opinion in Oncology 27, no. 6 (2015): 560–67. http://dx.doi.org/10.1097/cco.0000000000000223.

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6

Lavine, M. S. "Liquid Biopsy." Science 328, no. 5975 (2010): 141. http://dx.doi.org/10.1126/science.328.5975.141-a.

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7

Hekmat, K., and C. Bruns. "„Liquid biopsy“." Der Chirurg 90, S2 (2019): 120. http://dx.doi.org/10.1007/s00104-019-0845-0.

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8

Hekmat, K., and C. Bruns. "„Liquid biopsy“." Der Chirurg 88, no. 7 (2017): 621. http://dx.doi.org/10.1007/s00104-017-0458-4.

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9

Fulmer, Tim. "Liquid biopsy." Science-Business eXchange 5, no. 26 (2012): 668. http://dx.doi.org/10.1038/scibx.2012.668.

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10

Imyanitov, E. N., E. Sh Kuligina, and G. A. Janus. "LIQUID BIOPSY IN CLINICAL ONCOLOGY." Practical oncology 23, no. 4 (2022): 211–24. http://dx.doi.org/10.31917/2304211.

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Liquid biopsy is the analysis of tumor fragments (entire cells, nucleic acids,proteins) in hysiological and pathological body liquids. This technology has already been included in standard procedures of detecting secondary mutations, which are associate with acquired drug resistance. Liquid biopsy is a promising tool for early cancer detection, evaluation of the success of radical cancer surgery, monitoring of residual tumor disease, assessment of treatment efficacy etc.

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11

Ranuncolo, Stella Maris. "Liquid Biopsy in Liquid Tumors." Journal of Cancer Therapy 08, no. 03 (2017): 302–20. http://dx.doi.org/10.4236/jct.2017.83026.

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R, Dr Kalyani. "Liquid Biopsy : An emerging concept for diagnosis and management of cancer." JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES 09, no. 4 (2019): 91–96. http://dx.doi.org/10.58739/jcbs/v09i4.4.

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Tumour diagnosis is conventionally done by radiological findings and invasive surgical biopsy. Of late non-invasive technique where blood sample, urine and body fluids are used to extract circulating tumour cells (CTC) and genetic material for cancer diagnosis and treatment which is called as “Liquid Biopsy”.1,2 In this technique the liquid sample is used to isolate CTC, circulating tumour DNA (ctDNA), RNA, Exosomes and proteins which are shed by tumour cells into blood circulation, body fluids or urine in most of the cancers depending on the site of the can-cer. This technique enables non-inv

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13

Trombetta, Domenico, Angelo Sparaneo, Federico Pio Fabrizio, and Lucia Anna Muscarella. "Liquid biopsy and NSCLC." Lung Cancer Management 5, no. 2 (2016): 91–104. http://dx.doi.org/10.2217/lmt-2016-0006.

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14

Ronvaux, Lorian, Matteo Riva, An Coosemans, et al. "Liquid Biopsy in Glioblastoma." Cancers 14, no. 14 (2022): 3394. http://dx.doi.org/10.3390/cancers14143394.

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Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Despite recent advances in therapy modalities, the overall survival of GBM patients remains poor. GBM diagnosis relies on neuroimaging techniques. However, confirmation via histopathological and molecular analysis is necessary. Given the intrinsic limitations of such techniques, liquid biopsy (mainly via blood samples) emerged as a non-invasive and easy-to-implement alternative that could aid in both the diagnosis and the follow-up of GBM patients. Cancer cells release tumoral content into the bloodstream, such as circul

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15

Banys-Paluchowski, Maggie, Natalia Krawczyk, and Tanja Fehm. "Liquid Biopsy beim Mammakarzinom." Senologie - Zeitschrift für Mammadiagnostik und -therapie 18, no. 04 (2021): 365–76. http://dx.doi.org/10.1055/a-1678-1129.

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ZusammenfassungIn den letzten Jahren gewinnt die Liquid Biopsy, d. h. die blutbasierte Untersuchung von zirkulierenden Tumorzellen (CTCs) und Nukleinsäuren (DNA/RNA) beim Mammakarzinom zunehmend an Relevanz. Zahlreiche Studien haben bereits die hohe prognostische Bedeutung der CTC-Detektion sowohl im frühen als auch metastasierten Stadium gezeigt. Des Weiteren korrelieren die Veränderungen der CTC-Zahlen und der zirkulierenden Tumor-DNA (ctDNA) im Verlauf der Erkrankung mit dem Ansprechen auf die Therapie. Im Fokus der Forschung stehen derzeit die Liquid-Biopsy-basierten Therapieinterventionen

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16

Banys-Paluchowski, Maggie, Natalia Krawczyk, and Tanja Fehm. "Liquid Biopsy beim Mammakarzinom." TumorDiagnostik & Therapie 42, no. 05 (2021): 361–72. http://dx.doi.org/10.1055/a-1467-0165.

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ZusammenfassungIn den letzten Jahren gewinnt die Liquid Biopsy, d. h. die blutbasierte Untersuchung von zirkulierenden Tumorzellen (CTCs) und Nukleinsäuren (DNA/RNA) beim Mammakarzinom zunehmend an Relevanz. Zahlreiche Studien haben bereits die hohe prognostische Bedeutung der CTC-Detektion sowohl im frühen als auch metastasierten Stadium gezeigt. Des Weiteren korrelieren die Veränderungen der CTC-Zahlen und der zirkulierenden Tumor-DNA (ctDNA) im Verlauf der Erkrankung mit dem Ansprechen auf die Therapie. Im Fokus der Forschung stehen derzeit die Liquid-Biopsy-basierten Therapieinterventionen

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17

Rossi, Davide, Valeria Spina, Alessio Bruscaggin, and Gianluca Gaidano. "Liquid biopsy in lymphoma." Haematologica 104, no. 4 (2019): 648–52. http://dx.doi.org/10.3324/haematol.2018.206177.

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18

Poulet, Geoffroy, Joséphine Massias, and Valerie Taly. "Liquid Biopsy: General Concepts." Acta Cytologica 63, no. 6 (2019): 449–55. http://dx.doi.org/10.1159/000499337.

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Liquid biopsy provides the opportunity of detecting, analyzing and monitoring cancer in various body effluents such as blood or urine instead of a fragment of cancer tissue. It is composed of different biological matrices such as circulating tumor cells (CTCs), cell free nucleic acids, exosomes or tumors “educated platelets.” In addition to representing a non- or minimally invasive procedure, it should represent a better view of tumor heterogeneity and allows for real-time monitoring of cancer evolution. Recent technological and molecular advances, greatly facilitated by the use of microfluidi

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19

Rutkowska-Kawalec, Weronika, Karolina Michalczuk, Dariusz Fabian, et al. "Liquid biopsy - a review." Journal of Education, Health and Sport 77 (January 5, 2025): 56584. https://doi.org/10.12775/jehs.2025.77.56584.

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Introduction and objective:Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. Early detection is crucial for better outcomes. Traditional diagnostic methods, such as imaging and biopsies, often fail to detect HCC in early stages. Liquid biopsy, based on circulating free DNA (cfDNA) analysis, offers a promising, non-invasive approach, allowing frequent testing, addressing tumor heterogeneity, and reducing costs. Review methods:This article's databases were accessed through the WHO website, PubMed, and Google Scholar. A brief description of the state of knowled

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20

Fehm, Tanja N., Bianca Behrens, and Natalia Krawczyk. "Liquid Biopsy beim Mammakarzinom." gynäkologie + geburtshilfe 29, no. 6 (2024): 46–53. https://doi.org/10.1007/s15013-024-5946-2.

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21

Wu, Lingling, Yidi Wang, Lin Zhu, et al. "Aptamer-Based Liquid Biopsy." ACS Applied Bio Materials 3, no. 5 (2020): 2743–64. http://dx.doi.org/10.1021/acsabm.9b01194.

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22

Wakelee, H. "PC 03.03 Liquid Biopsy." Journal of Thoracic Oncology 12, no. 11 (2017): S1666—S1667. http://dx.doi.org/10.1016/j.jtho.2017.09.197.

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23

Salinas-Sánchez, A. S., C. Martínez-Sanchís, J. M. Giménez-Bachs, and D. C. García-Olmo. "Liquid biopsy in cancer." Actas Urológicas Españolas (English Edition) 40, no. 1 (2016): 1–2. http://dx.doi.org/10.1016/j.acuroe.2015.11.001.

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24

Stone, Louise. "Biomarkers from liquid biopsy." Nature Reviews Urology 13, no. 8 (2016): 434. http://dx.doi.org/10.1038/nrurol.2016.133.

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25

Behrend, Christian. "Liquid Biopsy beim Kolonkarzinom." Im Focus Onkologie 21, no. 3 (2018): 15–16. http://dx.doi.org/10.1007/s15015-018-3816-2.

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26

red. "Therapiekontrolle durch Liquid Biopsy." Info Onkologie 19, no. 8 (2016): 37. http://dx.doi.org/10.1007/s15004-016-5528-0.

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27

Reimers, Natalie, Claudia Hille, and Klaus Pantel. "Aktuelles zur Liquid Biopsy." InFo Onkologie 21, S1 (2018): 24–29. http://dx.doi.org/10.1007/s15004-018-6134-0.

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28

Harbour, J. William. "Liquid Biopsy in Retinoblastoma." JAMA Ophthalmology 135, no. 11 (2017): 1231. http://dx.doi.org/10.1001/jamaophthalmol.2017.4094.

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29

Voelker, Rebecca. "Liquid Biopsy Receives Approval." JAMA 316, no. 3 (2016): 260. http://dx.doi.org/10.1001/jama.2016.8833.

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30

Eibl, Robert H., and Markus Schneemann. "Liquid biopsy and glioblastoma." Exploration of Targeted Anti-tumor Therapy 4, no. 1 (2023): 28–41. http://dx.doi.org/10.37349/etat.2023.00121.

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Glioblastoma is the most common and malignant primary brain tumor. Despite a century of research efforts, the survival of patients has not significantly improved. Currently, diagnosis is based on neuroimaging techniques followed by histopathological and molecular analysis of resected or biopsied tissue. A recent paradigm shift in diagnostics ranks the molecular analysis of tissue samples as the new gold standard over classical histopathology, thus correlating better with the biological behavior of glioblastoma and clinical prediction, especially when a tumor lacks the typical hallmarks for gli

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31

Aziz, Zainab, Sophie Wagner, Alice Agyekum, et al. "Cost-Effectiveness of Liquid Biopsy for Colorectal Cancer Screening in Patients Who Are Unscreened." JAMA Network Open 6, no. 11 (2023): e2343392. http://dx.doi.org/10.1001/jamanetworkopen.2023.43392.

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ImportanceDespite recommendations for universal screening, adherence to colorectal cancer screening in the US is approximately 60%. Liquid biopsy tests are in development for cancer early detection, but it is unclear whether they are cost-effective for colorectal cancer screening.ObjectiveTo estimate the cost-effectiveness of liquid biopsy for colorectal cancer screening in the US.Design, Setting, and ParticipantsIn this economic evaluation, a Markov model was developed to compare no screening and 5 colorectal cancer screening strategies: colonoscopy, liquid biopsy, liquid biopsy following non

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32

Liu, Yaoping, and Wei Wang. "Multi-Modal Microfluidics (M3) for Sample Preparation of Liquid Biopsy: Bridging the Gap between Proof-of-Concept Demonstrations and Practical Applications." Micromachines 13, no. 2 (2022): 209. http://dx.doi.org/10.3390/mi13020209.

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Liquid biopsy, the technique used to shed light on diseases via liquid samples, has displayed various advantages, including minimal invasiveness, low risk, and ease of multiple sampling for dynamic monitoring, and has drawn extensive attention from multidisciplinary fields in the past decade. With the rapid development of microfluidics, it has been possible to manipulate targets of interest including cells, microorganisms, and exosomes at a single number level, which dramatically promotes the characterization and analysis of disease-related markers, and thus improves the capability of liquid b

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33

Saini, Aman, Yash Pershad, Hassan Albadawi, et al. "Liquid Biopsy in Gastrointestinal Cancers." Diagnostics 8, no. 4 (2018): 75. http://dx.doi.org/10.3390/diagnostics8040075.

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Liquid biopsy is the sampling of any biological fluid in an effort to enrich and analyze a tumor’s genetic material. Peripheral blood remains the most studied liquid biopsy material, with circulating tumor cells (CTC’s) and circulating tumor DNA (ctDNA) allowing the examination and longitudinal monitoring of a tumors genetic landscape. With applications in cancer screening, prognostic stratification, therapy selection and disease surveillance, liquid biopsy represents an exciting new paradigm in the field of cancer diagnostics and offers a less invasive and more comprehensive alternative to co

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34

Ho, Ho-Yin, Kei-See (Kasey) Chung, Chau-Ming Kan, and Sze-Chuen (Cesar) Wong. "Liquid Biopsy in the Clinical Management of Cancers." International Journal of Molecular Sciences 25, no. 16 (2024): 8594. http://dx.doi.org/10.3390/ijms25168594.

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Liquid biopsy, a noninvasive diagnosis that examines circulating tumor components in body fluids, is increasingly used in cancer management. An overview of relevant literature emphasizes the current state of liquid biopsy applications in cancer care. Biomarkers in liquid biopsy, particularly circulating tumor DNA (ctDNA), circulating tumor RNAs (ctRNA), circulating tumor cells (CTCs), extracellular vesicles (EVs), and other components, offer promising opportunities for early cancer diagnosis, treatment selection, monitoring, and disease assessment. The implementation of liquid biopsy in precis

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35

Ilié, Marius, and Paul Hofman. "Pros: Can tissue biopsy be replaced by liquid biopsy?" Translational Lung Cancer Research 5, no. 4 (2016): 420–23. http://dx.doi.org/10.21037/tlcr.2016.08.06.

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36

Corcoran, Ryan B. "Liquid biopsy versus tumor biopsy for clinical-trial recruitment." Nature Medicine 26, no. 12 (2020): 1815–16. http://dx.doi.org/10.1038/s41591-020-01169-6.

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37

Tan, Wan Ying, Snigdha Nagabhyrava, Olivia Ang-Olson, et al. "Translation of Epigenetics in Cell-Free DNA Liquid Biopsy Technology and Precision Oncology." Current Issues in Molecular Biology 46, no. 7 (2024): 6533–65. http://dx.doi.org/10.3390/cimb46070390.

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Technological advancements in cell-free DNA (cfDNA) liquid biopsy have triggered exponential growth in numerous clinical applications. While cfDNA-based liquid biopsy has made significant strides in personalizing cancer treatment, the exploration and translation of epigenetics in liquid biopsy to clinical practice is still nascent. This comprehensive review seeks to provide a broad yet in-depth narrative of the present status of epigenetics in cfDNA liquid biopsy and its associated challenges. It highlights the potential of epigenetics in cfDNA liquid biopsy technologies with the hopes of enha

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38

Cheung, Alvin Ho-Kwan, Chit Chow, and Ka-Fai To. "Latest development of liquid biopsy." Journal of Thoracic Disease 10, S14 (2018): S1645—S1651. http://dx.doi.org/10.21037/jtd.2018.04.68.

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39

Stickeler, Elmar. "Urindiagnostik – die neue Liquid Biopsy." Der Gynäkologe 54, no. 3 (2021): 175–80. http://dx.doi.org/10.1007/s00129-021-04749-w.

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40

Zmarzły, Nikola, Ewelina Hermyt, Andrzej Witek, Joanna Gola, and Urszula Mazurek. "Liquid biopsy in endometrial cancer." Current Gynecologic Oncology 17, no. 1 (2019): 27–42. http://dx.doi.org/10.15557/cgo.2019.0004.

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41

AKIN KABALAK, Pinar, and Ulku YILMAZ. "Liquid Biopsy in Lung Cancer." Güncel Göğüs Hastalıkları Serisi 6, no. 3 (2020): 18–22. http://dx.doi.org/10.5152/gghs.2018.036.

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42

Eibl, Robert H., and Markus Schneemann. "Liquid biopsy for monitoring medulloblastoma." Extracellular Vesicles and Circulating Nucleic Acids 3, no. 3 (2022): 263–74. http://dx.doi.org/10.20517/evcna.2022.36.

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Despite recent progress in molecular diagnostics defining four distinct medulloblastoma groups, the clinical management of these malignant childhood tumors of the cerebellum remains challenging. After surgical removal of the tumor, both cytotoxic chemotherapy and irradiation can offer additional curative benefits, but they also include a significant risk of long-term damage. Early molecular profiling aims to predict the outcome of such aggressive therapies. This prevents unnecessary damage to patients who may not need it and helps to identify those patients with remaining tumor cells who may b

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43

Sahoo, TapanKumar. "Liquid biopsy in oncology practice." Oncology Journal of India 2, no. 3 (2018): 45. http://dx.doi.org/10.4103/oji.oji_32_18.

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44

Ranade, A. A., A. Bhatt, Darshana Patil, et al. "Liquid biopsy in periampullary carcinoma." International Journal of Molecular and Immuno Oncology 1, no. 1 (2016): 45. http://dx.doi.org/10.18203/issn.2456-3994.intjmolimmunooncol20164388.

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<p style="margin: 0in 0in 8pt 0.25in; text-align: justify;">Periampullary cancers are rare tumors arising within 2 cm of the major papilla of the duodenum. In this case report, we describe the use of liquid biopsy to analyze cell-free tumor DNA and exosomal microRNA to guide treatment selection in a patient with periampullary adenocarcinoma. To our knowledge, this is the first time such case report has been described in the literature.</p>

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45

Pankaj, Sangeeta. "Liquid biopsy in ovarian carcinoma." Journal of Indira Gandhi Institute Of Medical Sciences 7, no. 2 (2021): 79. http://dx.doi.org/10.4103/jigims.jigims_47_21.

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46

Mahdi, Ahmed. "LIQUID BIOPSY- A NEW PROSPECT." Iraqi Journal of Medical Sciences 16, no. 4 (2018): 353–56. http://dx.doi.org/10.22578/ijms.16.4.1.

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Tissue biopsy has been the mainstay in tumor diagnosis for centuries. But due to its invasiveness and the heterogeneity of tumors there was a need for an alternative or adjuvant techniques to diagnose and assess tumors. Liquid biopsy is emerging as a new technique that will open the way for the diagnosis, tumor characterization, assess disease prognosis and individualize treatment options in cancer patients. Keywords:Biopsy, CTC, ctDNA Citation: Mahdi AK. Liquid biopsy - A new prospect. Iraqi JMS. 2018; 16(4): 353-356. doi: 10.22578/IJMS.16.4.1

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47

Ueda, Koji. "Cancer liquid biopsy using exosomes." Electrophoresis Letters 61, no. 2 (2017): 65–68. http://dx.doi.org/10.2198/electroph.61.65.

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48

Lousada-Fernandez, Fatima, Oscar Rapado-Gonzalez, Jose-Luis Lopez-Cedrun, Rafael Lopez-Lopez, Laura Muinelo-Romay, and Maria Suarez-Cunqueiro. "Liquid Biopsy in Oral Cancer." International Journal of Molecular Sciences 19, no. 6 (2018): 1704. http://dx.doi.org/10.3390/ijms19061704.

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49

Santise, G., D. Maselli, C. Mignogna, et al. "RF41 LIQUID BIOPSY FORCARDIAC TUMORS." Journal of Cardiovascular Medicine 19 (November 2018): e77. http://dx.doi.org/10.2459/01.jcm.0000550086.27815.c2.

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50

Lissa, Delphine, and Ana I. Robles. "Methylation analyses in liquid biopsy." Translational Lung Cancer Research 5, no. 5 (2016): 492–504. http://dx.doi.org/10.21037/tlcr.2016.10.03.

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