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Journal articles on the topic 'Liquid handling'

Author: Grafiati
Published: 4 June 2021
Last updated: 8 February 2022

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1

Marx, Vivien. "Pouring over liquid handling." Nature Methods 11, no. 1 (December 30, 2013): 33–38. http://dx.doi.org/10.1038/nmeth.2785.

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2

Berg, Michael, Katrin Undisz, Ralf Thiericke, Peter Zimmermann, Thomas Moore, and Clemens Posten. "Evaluation of Liquid Handling Conditions in Microplates." Journal of Biomolecular Screening 6, no. 1 (February 2001): 47–56. http://dx.doi.org/10.1177/108705710100600107.

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Liquid handling in higher density microplates (e.g., 1536-well microplates) for more efficient drug screening necessitates carefully selected and optimized parameters. The quality of a liquid handling procedure is dependent on the carryover rate of residual liquids during the pipetting process, the mixing behavior in the wells, foam and bubble formation, and evaporation. We compared and optimized these parameters in 96-, 384-, and 1536-well microplates, and herein we critically evaluate the performance of the CyBi™-Well 96/384/1536 automated micropipetting device, which formed the basis of our evaluation studies.
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3

Sihono, Sihono, Kustiariyah Tarman, Hawis Madduppa, and Hedi Indra Januar. "Metabolite Profiles and Antioxidant Activity of Caulerpa racemosa with Different Handlings." Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology 13, no. 3 (December 30, 2018): 93. http://dx.doi.org/10.15578/squalen.v13i3.355.

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Metabolite profiles and antioxidant activity of Caulerpa racemosa extract with different handlings were investigated. Three different handlings during transportation were applied, namely samples chilled with ice, stored in liquid nitrogen and soaked in seawater. The different handling significantly affected the yield of ethanolic crude extracts and inorganic fractions but insignificantly to organic fractions. Different handlings resulted in differences of major fractions of C. racemosa extracts. Major fractions of the sample that was handled with chilling temperature contained low polar fractions (K10, K11, K12, and K13), while seawater handling extract contained very polar (K1, K2 and K3), polar (K6, K7, and K8) and low polar (K13) fractions. The extract of the sample handled in liquid nitrogen contained balanced fractions. Chilling temperature handling produced highest antioxidant activity (IC50 below 2,000 ppm) in ethanolic extract of C. racemosa. Keywords: antioxidant activity, Caulerpa racemosa, ethanolic extract,handlings, IC50
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4

Martin, A. L., and J. Petracca. "Liquid handling in robotic workstations." Nature 343, no. 6256 (January 1990): 391–92. http://dx.doi.org/10.1038/343391a0.

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5

Laube, Wendy M. "Process Security for Liquid Handling." Genetic Engineering & Biotechnology News 31, no. 6 (March 15, 2011): 36–37. http://dx.doi.org/10.1089/gen.31.6.13.

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6

Doyle, Ken. "Labs Embrace Automated Liquid Handling." Genetic Engineering & Biotechnology News 34, no. 12 (June 15, 2014): 12, 14–15. http://dx.doi.org/10.1089/gen.34.12.07.

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7

Bauer, Hermann, Joachim Kinkel, Walter Stark, and Peter Volgnandt. "Automatisierung im Labor: Liquid handling." Nachrichten aus Chemie, Technik und Laboratorium 44, no. 9 (September 1996): M55—M75. http://dx.doi.org/10.1002/nadc.19960440931.

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8

Marx, Vivien. "Erratum: Pouring over liquid handling." Nature Methods 11, no. 3 (February 27, 2014): 349. http://dx.doi.org/10.1038/nmeth0314-349a.

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9

Horton, Brendan. "Making waves with liquid handling." Nature 374, no. 6518 (March 1995): 197–98. http://dx.doi.org/10.1038/374197a0.

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10

Dilorenzo, M. "Technological Advancements in Liquid Handling Robotics." Journal of the Association for Laboratory Automation 6, no. 2 (May 1, 2001): 36–40. http://dx.doi.org/10.1016/s1535-5535(04)00123-6.

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11

DiLorenzo, Maria E., Conal F. Timoney, and Robin A. Felder. "Technological Advancements in Liquid Handling Robotics." JALA: Journal of the Association for Laboratory Automation 6, no. 2 (April 2001): 36–40. http://dx.doi.org/10.1016/s1535-5535-04-00123-6.

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12

O'Neill, Michael D. "Increasing Throughput with Automated Liquid Handling." Genetic Engineering & Biotechnology News 32, no. 12 (June 15, 2012): 18–21. http://dx.doi.org/10.1089/gen.32.12.06.

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13

Roberts, Josh P. "Liquid Handling Needs a Helping Hand." Genetic Engineering & Biotechnology News 33, no. 12 (June 15, 2013): 1, 18–19. http://dx.doi.org/10.1089/gen.33.12.08.

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14

Felton, Michael J. "Product Review: Liquid handling: Dispensing reliability." Analytical Chemistry 75, no. 17 (September 2003): 397 A—399 A. http://dx.doi.org/10.1021/ac031388u.

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15

Kong, Fanwei, Liang Yuan, Yuan F. Zheng, and Weidong Chen. "Automatic Liquid Handling for Life Science." Journal of Laboratory Automation 17, no. 3 (February 6, 2012): 169–85. http://dx.doi.org/10.1177/2211068211435302.

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16

Abdelgawad, Mohamed. "Digital Microfluidics: Automating Microscale Liquid Handling." IEEE Nanotechnology Magazine 14, no. 3 (June 2020): 6–23. http://dx.doi.org/10.1109/mnano.2020.2966204.

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17

Heller, Rainer, and Jan Carsten Pieck. "Ultraschallbasiertes Liquid-Handling in der Wirkstoffforschung." BIOspektrum 20, no. 4 (June 2014): 419–20. http://dx.doi.org/10.1007/s12268-014-0459-5.

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18

Shvets, I. V., S. Makarov, C. Franken, A. Shvets, D. Sweeney, and J. Osing. "Spot-on™ Technology for Low Volume Liquid Handling." JALA: Journal of the Association for Laboratory Automation 7, no. 6 (December 2002): 125–29. http://dx.doi.org/10.1016/s1535-5535-04-00233-3.

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The article describes the new proprietary spot-on™ technology developed by Allegro Technologies, Ltd., for nanolitre and microlitre dispensing of liquids for the drug discovery, genomics and proteomics industries. We analyze the requirements of the drug discovery industry for low volume liquid handling technologies and briefly summarize some the more common technologies currently available. A detailed description is provided of the new spot-on™ technology in terms of function and operation as well as the relevant features and potential benefits to using this new method of nanolitre dispensing.
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19

Li, Baichen, Lin Li, Allan Guan, Quan Dong, Kangcheng Ruan, Ronggui Hu, and Zhenyu Li. "A smartphone controlled handheld microfluidic liquid handling system." Lab Chip 14, no. 20 (2014): 4085–92. http://dx.doi.org/10.1039/c4lc00227j.

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20

Fransas, Anne. "UNIQUE LIQUID CARGO HANDLING SIMULATOR IN FINLAND." International Oil Spill Conference Proceedings 2008, no. 1 (May 1, 2008): 177–78. http://dx.doi.org/10.7901/2169-3358-2008-1-177.

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ABSTRACT Most of the hazardous incidents and accidents in liquid terminals occur during the cargo handling operations, i.e. tanker loading and discharging. The main reason of these incidents is lack of cooperation and communication between the terminal and the ship. Kymenlaakson ammattikorkeakoulu, University of Applied Sciences (UAS) and the Kymenlaakso Region in Southeast Finland aim to improve the operational safety in tanker terminals. One example of this is the Liquid Cargo Handling Simulator located in Kotka in the Seafaring and Logistics Department of Kymenlaakso UAS. The simulator unit consists of two parts, the tanker and the terminal simulator, which are integrated together. In case of oil spill accidents it is possible to train oil combating with the help of PISCESII Oil Spill Management Simulator which is also on part of this unit. The simulator enables the practice of the loading and discharging of different types of tankers and railway wagons. The training aims to teach routine practises as well as safety practises in certain risk situations. It includes also the theoretical part and it is directed at all personnel and students of the field who deal with liquid cargoes in ports. The simulator will be used in the basic studies of Kymenlaakson ammattikorkeakoulu UAS, as part of course activities, and in the training of its personnel and interest groups. The production of the Kymenlaakso University of Applied Sciences’ simulator programme is carried out by Transas from St. Petersburg, a world-leading developer and supplier of Information Technology solutions for the maritime industry. Neste Oil, Port of Porvoo, also contributed to the project. The liquid terminal simulator project is financed by European Union, State Provincial Office of Southern Finland, Kymenlaakson ammattikorkeakoulu, Crystal Pool Ltd, Port of H amina Ltd, Vopak Chemicals Logistics Finland Oy, Neste Oil Oy, Kauko-Telko Oy, SGS Inspection Services Oy, and Baltic Tank Oy.
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21

Streat, Michael. "Slurry handling: Design of solid-liquid systems." Powder Technology 73, no. 2 (December 1992): 191. http://dx.doi.org/10.1016/0032-5910(92)80081-7.

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22

Shamlou, P. A. "Slurry Handling: Design of Solid—Liquid Systems." Chemical Engineering Science 48, no. 10 (1993): 1923–24. http://dx.doi.org/10.1016/0009-2509(93)80365-w.

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23

Nasti, Giuseppe, Sara Coppola, Veronica Vespini, Simonetta Grilli, Antonio Vettoliere, Carmine Granata, and Pietro Ferraro. "Pyroelectric Tweezers for Handling Liquid Unit Volumes." Advanced Intelligent Systems 2, no. 10 (July 2020): 2000044. http://dx.doi.org/10.1002/aisy.202000044.

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24

Gaisford, Wendy. "Robotic Liquid Handling and Automation in Epigenetics." Journal of Laboratory Automation 17, no. 5 (October 2012): 327–29. http://dx.doi.org/10.1177/2211068212457160.

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25

TSUCHIYA, Kensuke, Kei NAKATA, Yoichi NAKAMOTO, Takeshi OOI, Sota FUJIOKA, and Masayuki NAKAO. "Micro dispenser for handling picoliter-scale liquid." Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2002.14 (2002): 207–8. http://dx.doi.org/10.1299/jsmebio.2002.14.207.

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26

Neil, W. A. "Slurry handling design of solid-liquid systems." Minerals Engineering 6, no. 1 (January 1993): 108. http://dx.doi.org/10.1016/0892-6875(93)90169-n.

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27

de Cuyper, J. "Slurry handling design of solid-liquid systems." International Journal of Mineral Processing 37, no. 3-4 (March 1993): 299–300. http://dx.doi.org/10.1016/0301-7516(93)90033-7.

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28

Lorenz, Matthias G. O. "Liquid-handling robotic workstations for functional genomics." Journal of the Association for Laboratory Automation 9, no. 4 (August 2004): 262–67. http://dx.doi.org/10.1016/j.jala.2004.03.010.

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29

WENDEL, G. "Liquid Handling With Adaptive Real-Time Validation." Journal of the Association for Laboratory Automation 11, no. 2 (April 2006): 88–91. http://dx.doi.org/10.1016/j.jala.2005.12.001.

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30

Vessey, Andrew, and Gregory Porter. "Optimization of Liquid-Handling Precision with Neptune Software on a Tecan Genesis." JALA: Journal of the Association for Laboratory Automation 7, no. 4 (August 2002): 81–84. http://dx.doi.org/10.1016/s1535-5535-04-00212-6.

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The process of optimizing the precision of robotic liquid-handling instruments can be improved using the Design of Experiments methodology. Design of Experiments (DOE) is “a collection of statistical and mathematical techniques useful for developing, improving, and optimizing processes.” Using DOE one can design and analyze experiments with the goal of optimizing the precision of liquid deliveries. Tecan has developed a software application, “Neptune” to automate this process for the Tecan Genesis series of instruments. This application has been used to perform experiments on the liquid-handling properties of a variety of liquids. As an example of this process, we will examine a set of experiments performed on a 50% concentration of polyethylene glycol 8000. These experiments resulted in an improvement in the pipetting precision from an average CV of 22.2% to an average of 2.9%.
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31

Song, Younghoon, Yunjin Jeong, Taehong Kwon, Daewon Lee, Dong Yoon Oh, Tae-Joon Park, Junhoi Kim, Jiyun Kim, and Sunghoon Kwon. "Liquid-capped encoded microcapsules for multiplex assays." Lab on a Chip 17, no. 3 (2017): 429–37. http://dx.doi.org/10.1039/c6lc01268j.

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Although droplet microfludics is a promising technology for handling a number of liquids of a single type of analyte, it has limitations in handling thousands of different types of analytes for multiplex assay.
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32

Yang, Zhen-Zhou, Xian-Ku Zhang, and Jing-Hua Cao. "Discharging Part of LNG Liquid Cargo Handling Simulator." Research Journal of Applied Sciences, Engineering and Technology 6, no. 21 (November 20, 2013): 3978–85. http://dx.doi.org/10.19026/rjaset.6.3499.

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33

Wilson, Daniel J., and Charles R. Mace. "Reconfigurable Pipet for Customized, Cost-Effective Liquid Handling." Analytical Chemistry 89, no. 17 (August 11, 2017): 8656–61. http://dx.doi.org/10.1021/acs.analchem.7b02556.

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34

Stanchfield, J. "Submicroliter Liquid Handling 384 Wells at a Time." Journal of the Association for Laboratory Automation 4, no. 3 (June 1, 1999): 54–56. http://dx.doi.org/10.1016/s1535-5535(04)80014-5.

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35

Stanchfield, James E. "Submicroliter Liquid Handling 384 Wells at a Time." JALA: Journal of the Association for Laboratory Automation 4, no. 3 (June 1999): 54–56. http://dx.doi.org/10.1016/s1535-5535-04-80014-5.

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36

Schmidtchen, U., Th Gradt, and G. Würsig. "Safe handling of large quantities of liquid hydrogen." Cryogenics 33, no. 8 (August 1993): 813–17. http://dx.doi.org/10.1016/0011-2275(93)90193-r.

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37

He, Nongyue, Ting Liu, and Bin Liu. "Technologies and Applications in Micro-Volume Liquid Handling." Journal of Nanoscience and Nanotechnology 16, no. 1 (January 1, 2016): 58–66. http://dx.doi.org/10.1166/jnn.2016.11681.

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38

Xiao, Andrew S., Eric S. Lightcap, and David C. Bouck. "Acoustic Liquid Handling for Rapid siRNA Transfection Optimization." Journal of Biomolecular Screening 20, no. 8 (April 29, 2015): 957–64. http://dx.doi.org/10.1177/1087057115583808.

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Gene knockdown by small interfering RNA (siRNA) has been used extensively to investigate the function of genes in targeted and genome-wide studies. One of the primary challenges of siRNA studies of any scale is to achieve sufficient gene knockdown to produce the biological changes that lead to measurable phenotypes. Reverse, lipid-based transfection efficiency minimally requires the optimization of the following parameters: cell number, knockdown duration, siRNA oligonucleotide concentration, type/brand of transfection lipid, and transfection lipid concentration. In this study, we describe a methodology to utilize the flexibility and low-volume range of the Echo acoustic liquid handler to rapidly screen a matrix of transfection conditions. The matrix includes six different transfection lipids from three separate vendors across a broad range of concentrations. Our results validate acoustic liquid transfer for the delivery of siRNAs and transfection reagents. Finally, this methodology is applied to rapidly optimize transfection conditions across many tissue culture cell lines derived from various originating tissues.
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39

Rindt, P., T. W. Morgan, M. A. Jaworski, and N. J. Lopes Cardozo. "Power handling limit of liquid lithium divertor targets." Nuclear Fusion 58, no. 10 (July 31, 2018): 104002. http://dx.doi.org/10.1088/1741-4326/aad290.

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40

Lin, Rongsheng, and Mark A. Burns. "Surface-modified polyolefin microfluidic devices for liquid handling." Journal of Micromechanics and Microengineering 15, no. 11 (October 10, 2005): 2156–62. http://dx.doi.org/10.1088/0960-1317/15/11/023.

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41

KURIYAMA, Yoshifumi, and Ken'ichi YANO. "Liquid Handling Control Considering Spilling Avoidance(Mechanical Systems)." Transactions of the Japan Society of Mechanical Engineers Series C 75, no. 754 (2009): 1690–97. http://dx.doi.org/10.1299/kikaic.75.1690.

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42

Hentz, Nathaniel G., and Tanya R. Knaide. "Effect of Liquid-Handling Accuracy on Assay Performance." Journal of Laboratory Automation 19, no. 2 (April 2014): 153–62. http://dx.doi.org/10.1177/2211068213504095.

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43

Olechno, Joe, Clive Green, and Lynn Rasmussen. "Why a Special Issue on Acoustic Liquid Handling?" Journal of Laboratory Automation 21, no. 1 (February 2016): 1–3. http://dx.doi.org/10.1177/2211068215619712.

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44

Waldbaur, Ansgar, Jörg Kittelmann, Carsten P. Radtke, Jürgen Hubbuch, and Bastian E. Rapp. "Microfluidics on liquid handling stations (μF-on-LHS): an industry compatible chip interface between microfluidics and automated liquid handling stations." Lab on a Chip 13, no. 12 (2013): 2337. http://dx.doi.org/10.1039/c3lc00042g.

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45

Hayes, John J. "BASS STRAIT WATER HANDLING DEVELOPMENTS." APPEA Journal 25, no. 1 (1985): 114. http://dx.doi.org/10.1071/aj84009.

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Esso Australia Ltd operates, on behalf of Esso/BHP, a crude oil and natural gas producing and processing facility in the Gippsland Basin, Victoria. Saline formation water produced with the oil is treated and discharged overboard from offshore platforms wherever possible to limit the volume of saline water in the pipeline system and avoid onshore disposal of saline water. Esso has developed oily water treatment and continuous oil-in- water monitoring beyond conventional technology and operates within stringent overboard water discharge regulations. Initial oily water treating installations were Cross Flow Interceptors, a corrugated plate gravity separator. Unsatisfactory performance prompted investigations leading to development of the Dissolved Gas Flotation unit using evolved gas to lift oil droplets to the surface. These units operate successfully offshore today. The most recent developments have been associated with a liquid-liquid hydrocyclone trade named 'Vortoil'. This has been tested offshore with an 'Purometer' continuous oil-in-water monitor. The Vortoil and Purometer have both performed favourably and proven a compact, low cost combination for future water treating installations.
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46

Sato, Hiroki, Sayaka Ban, and Tsuyoshi Hosoya. "Handling specimens in liquid preservative: adding and removing the liquid paraffin overlayer." Mycoscience 52, no. 5 (September 2011): 354–55. http://dx.doi.org/10.1007/s10267-011-0108-5.

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47

Haberkorn, Michael, Johannes Frank, Michael Harasek, Johan Nilsson, Thomas Laurell, and Bernhard Lendl. "Flow-through Picoliter Dispenser: A New Approach for Solvent Elimination in FT-IR Spectroscopy." Applied Spectroscopy 56, no. 7 (July 2002): 902–8. http://dx.doi.org/10.1366/000370202760171581.

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A new interface for FT-IR analysis of liquid samples on the basis of solvent elimination is presented. The approach is based on a piezoactuated flow-through microdispenser, a device built of two microstructured silicon wafers designed for micro-liquid handling. It could be verified during preliminary studies using a sequential injection (SI) system for automated liquid handling that the flow-through microdispenser as a possible interface for flow system–FT-IR analysis has the capability of meeting the demands of hyphenated miniaturized liquid handling systems (e.g., μ-HPLC, microhigh performance liquid chromatography), as it successfully provides highly stable, reliable and reproducible operating conditions for liquid handling in the picoliter range. Moreover, an increase in sensitivity for FT-IR measurements could be achieved, lowering the mass detection limit of sugars (such as the investigated sucrose) to 53 picograms. As is demonstrated on the example of an HPLC separation of a mixture of glucose and fructose, interfacing LC systems to FT-IR using a piezoactuated flow-through microdispenser is a feasible and promising approach.
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48

Grant, Richard John, Karen Roberts, Carly Pointon, Clare Hodgson, Lynsey Womersley, Darren Craig Jones, and Eric Tang. "Achieving Accurate Compound Concentration in Cell-Based Screening: Validation of Acoustic Droplet Ejection Technology." Journal of Biomolecular Screening 14, no. 5 (June 2009): 452–59. http://dx.doi.org/10.1177/1087057109336588.

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Compound handling is a fundamental and critical step in compound screening throughout the drug discovery process. Although most compound-handling processes within compound management facilities use 100% DMSO solvent, conventional methods of manual or robotic liquid-handling systems in screening workflows often perform dilutions in aqueous solutions to maintain solvent tolerance of the biological assay. However, the use of aqueous media in these applications can lead to suboptimal data quality due to compound carryover or precipitation during the dilution steps. In cell-based assays, this effect is worsened by the unpredictable physical characteristics of compounds and the low DMSO tolerance within the assay. In some cases, the conventional approaches using manual or automated liquid handling resulted in variable IC50 dose responses. This study examines the cause of this variability and evaluates the accuracy of screening data in these case studies. A number of liquid-handling options have been explored to address the issues and establish a generic compound-handling workflow to support cell-based screening across our screening functions. The authors discuss the validation of the Labcyte Echo reformatter as an effective noncontact solution for generic compound-handling applications against diverse compound classes using triple-quad liquid chromatography/mass spectrometry. The successful validation and implementation challenges of this technology for direct dosing onto cells in cell-based screening is discussed. ( Journal of Biomolecular Screening 2009:452-459)
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49

Koshimizu, Shigeomi. "Application of Liquid Bridging Force in Manipulation and Assembly of Microparts." International Journal of Automation Technology 3, no. 3 (May 5, 2009): 308–12. http://dx.doi.org/10.20965/ijat.2009.p0308.

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Development of methods for handling such microparts will increasingly be needed. Microparts are commonly handled by gripping, using tweezers for example. However, this method poses difficulties in quick release, due to static electricity. Here we propose a new handling method based on liquid bridging force. The pick & place method and the assembly method using liquid bridging force for microparts are shown in this paper. Measurement results of liquid bridging force are also described. Effects of parameters such as liquid type, picking up speed and curvature of microparts were investigated.
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50

Nguyen, Nam-Trung, Majid Hejazian, Chin Ooi, and Navid Kashaninejad. "Recent Advances and Future Perspectives on Microfluidic Liquid Handling." Micromachines 8, no. 6 (June 12, 2017): 186. http://dx.doi.org/10.3390/mi8060186.

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