Academic literature on the topic 'Lisosan G, bariatric surgery, glucagon-like peptide-1, obesity'

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Journal articles on the topic "Lisosan G, bariatric surgery, glucagon-like peptide-1, obesity"

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Xie, Cong, Weikun Huang, Richard L. Young, et al. "Role of Bile Acids in the Regulation of Food Intake, and Their Dysregulation in Metabolic Disease." Nutrients 13, no. 4 (2021): 1104. http://dx.doi.org/10.3390/nu13041104.

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Bile acids are cholesterol-derived metabolites with a well-established role in the digestion and absorption of dietary fat. More recently, the discovery of bile acids as natural ligands for the nuclear farnesoid X receptor (FXR) and membrane Takeda G-protein-coupled receptor 5 (TGR5), and the recognition of the effects of FXR and TGR5 signaling have led to a paradigm shift in knowledge regarding bile acid physiology and metabolic health. Bile acids are now recognized as signaling molecules that orchestrate blood glucose, lipid and energy metabolism. Changes in FXR and/or TGR5 signaling modulat
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Coleman, Michael F., Elaine M. Glenny, Tori L. McFarlane, et al. "Abstract 2188: Tirzepatide treatment restores antitumor immunity in a model of obesity-driven cancer." Cancer Research 84, no. 6_Supplement (2024): 2188. http://dx.doi.org/10.1158/1538-7445.am2024-2188.

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Abstract Obesity is a widely and increasingly prevalent disease and a risk factor for several cancers. Recent work has shown that weight loss following bariatric surgery is potently protective against obesity-associated cancers. However, little is known about the potential anticancer effects of weight loss achieved through incretin-based therapies. We therefore interrogated the effects of the dual glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide receptor agonist tirzepatide (TZP) on body weight and tumor progression in a mouse model of obesity and transplanted colon can
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Zeng, Yuan, Yifan Wu, Qian Zhang, and Xinhua Xiao. "Crosstalk between glucagon-like peptide 1 and gut microbiota in metabolic diseases." mBio, December 6, 2023. http://dx.doi.org/10.1128/mbio.02032-23.

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ABSTRACT Gut microbiota exert influence on gastrointestinal mucosal permeability, bile acid metabolism, short-chain fatty acid synthesis, dietary fiber fermentation, and farnesoid X receptor/Takeda G protein-coupled receptor 5 (TGR5) signal transduction. The incretin glucagon-like peptide 1 (GLP-1) is mainly produced by L cells in the gut and regulates postprandial blood glucose. Changes in gut microbiota composition and function have been observed in obesity and type 2 diabetes (T2D). Meanwhile, the function and rhythm of GLP-1 have also been affected in subjects with obesity or T2D. Therefor
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Jalleh, Ryan Joseph, Mahesh Michael Umapathysivam, Mark Philip Plummer, Adam Deane, Karen Louise Jones, and Michael Horowitz. "Postprandial plasma GLP-1 levels are elevated in individuals with postprandial hypoglycaemia following Roux-en-Y gastric bypass – a systematic review." Reviews in Endocrine and Metabolic Disorders, July 13, 2023. http://dx.doi.org/10.1007/s11154-023-09823-3.

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AbstractBackground and aims: Bariatric surgery is the most effective treatment in individuals with obesity to achieve remission of type 2 diabetes. Post-bariatric surgery hypoglycaemia occurs frequently, and management remains suboptimal, because of a poor understanding of the underlying pathophysiology. The glucoregulatory hormone responses to nutrients in individuals with and without post-bariatric surgery hypoglycaemia have not been systematically examined. Materials and methods: The study protocol was prospectively registered with PROSPERO. PubMed, EMBASE, Web of Science and the Cochrane d
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Skuratovskaia, Daria, Maria Vulf, Nataliya Chasovskikh, et al. "The Links of Ghrelin to Incretins, Insulin, Glucagon, and Leptin After Bariatric Surgery." Frontiers in Genetics 12 (April 20, 2021). http://dx.doi.org/10.3389/fgene.2021.612501.

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Type 2 diabetes mellitus (T2DM) is one of the most prominent and socially significant problems. The present study aimed to identify the mechanisms of interaction of critical regulators of carbohydrate metabolism using bioinformatics and experimental methods and to assess their influence on the development of T2DM. We conducted an in silico search for the relationship of hormones and adipokines and performed functional annotation of the receptors for ghrelin and incretins. Hormones and adipokines were assessed in the plasma of obese patients with and without T2DM as well as after laparoscopic s
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Finn, Erin, Kelly N. Z. Fuller, Leslie A. Knaub, et al. "OR15-03 Lower Hepatic Mitochondrial Respiration Relates To Dysmetabolism In Adolescents With Severe Obesity." Journal of the Endocrine Society 7, Supplement_1 (2023). http://dx.doi.org/10.1210/jendso/bvad114.1511.

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Abstract Disclosure: E. Finn: None. K.N. Fuller: None. L.A. Knaub: None. Y. Garcia Reyes: None. S.C. Derderian: None. J. Schoen: None. T. Inge: None. J.E. Reusch: Advisory Board Member; Self; Medtronic Diabetes. K. Nadeau: None. M. Cree: None. Introduction: The severity of metabolic disease in youth with obesity is varied and determinants of disease progression are not known. Non-alcoholic fatty liver disease appears to be central to the development of cardiometabolic disease in youth with severe obesity. We tested the hypothesis that hepatic mitochondrial respiratory capacity would correlate
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Volek, Jeff S., Madison L. Kackley, and Alex Buga. "Nutritional Considerations During Major Weight Loss Therapy: Focus on Optimal Protein and a Low-Carbohydrate Dietary Pattern." Current Nutrition Reports, May 30, 2024. http://dx.doi.org/10.1007/s13668-024-00548-6.

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Abstract Purpose of Review Considering the high prevalence of obesity and related metabolic impairments in the population, the unique role nutrition has in weight loss, reversing metabolic disorders, and maintaining health cannot be overstated. Normal weight and well-being are compatible with varying dietary patterns, but for the last half century there has been a strong emphasis on low-fat, low-saturated fat, high-carbohydrate based approaches. Whereas low-fat dietary patterns can be effective for a subset of individuals, we now have a population where the vast majority of adults have excess
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Dissertations / Theses on the topic "Lisosan G, bariatric surgery, glucagon-like peptide-1, obesity"

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Moriconi, Diego. "Efficacy of Lisosan G (fermented wheat) on post-prandial hypoglycemia after bariatric surgery." Doctoral thesis, Università di Siena, 2023. https://hdl.handle.net/11365/1227315.

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Introduction: post-bariatric hypoglycemia (PBH) is considered a chronic complication after bariatric surgery that increase cardiovascular risk. Changes in gut microbiota and a dysregulated inflammatory response to a glucose load seems to be the conditions favoring the development of PBH. Lisosan G (LG) is a fermented powder obtained from whole grains (Triticum aestivum), rich in polyphenols and flavonoids with antioxidant, anti-inflammatory and prebiotic properties. Aims: The aims of the study were 1) to evaluate the effectiveness of using LG added to the diet in reducing PBH event
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