Relevant bibliographies by topics / Lithium pharmacodynamics

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters

Academic literature on the topic 'Lithium pharmacodynamics'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Lithium pharmacodynamics"

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Ware, Kenric, Erika Tillery, and Lauren Linder. "General pharmacokinetic/pharmacodynamic concepts of mood stabilizers in the treatment of bipolar disorder." Mental Health Clinician 6, no. 1 (2016): 54–61. http://dx.doi.org/10.9740/mhc.2016.01.054.

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Abstract Introduction Mood stabilizers are the recommended treatment for patients who receive a diagnosis of bipolar disorder. Because of the necessity of mood stabilizer treatment in patients with bipolar disorder and the extent of pharmacokinetic and pharmacodynamic principles involved, the purpose of this review is to summarize the pharmacokinetic principles of lithium in addition to the pharmacodynamics of lithium, carbamazepine, lamotrigine, and valproic acid/valproate. Methods Practice guidelines, review articles, and clinical trials were located using online databases PubMed, CINAHL, ID
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Smith, Donald F. "Lithium Chloride Toxicity and Pharmacodynamics in Inbred Mice." Acta Pharmacologica et Toxicologica 43, no. 1 (2009): 51–54. http://dx.doi.org/10.1111/j.1600-0773.1978.tb02231.x.

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Andy, R. Eugene, Masiak Jolanta, Masiak Marek, and Kapica Jacek. "BRAIN Journal - Isolating the Norepinephrine Pathway Comparing Lithium in Bipolar Patients to SSRIs in Depressive Patients." BRAIN - Broad Research in Artificial Intelligence and Neuroscience 5, no. 1-4 (2014): 5–15. https://doi.org/10.5281/zenodo.1044129.

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ABSTRACT Introduction: The purpose of this investigatory neuroimaging analysis was done to better understand the pharmacodynamics of Lithium by isolating the norepinephrine pathway in the brain. To accomplish this, we compared patients with Bipolar Disorder treated with Lithium to patients diagnosed with Major Depression or Depressive Disorder who are treated with Selective Serotonin Reuptake Inhibitors (SSRIs). Methodology: We used Standardized Low Resolution Brain Electrotomography to calculate the whole brain, voxel-by-voxel, unpaired t-tests Statistical non-Parametric Maps. For our first e
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Kanellis, Vangelis George, and Ramila Varendran. "Accidental chronic lithium toxicity." International Journal of Basic & Clinical Pharmacology 7, no. 12 (2018): 2456. http://dx.doi.org/10.18203/2319-2003.ijbcp20184865.

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Lithium is an effective first-line mood stabiliser for bipolar disorder, treatment-refractory depression and suicide prevention. Studies have demonstrated its ability to produce neuroprotective benefits. Despite this, Lithium can cause neurotoxicity, cardiotoxicity and endocrine derangement resulting in severe (and potentially permanent) side effects. Lithium toxicity can be precipitated by illness, salt restriction diets, dehydration, nephrogenic diabetes insipidus, impaired creatinine clearance, concomitant drugs. This is particularly true in older patients with altered pharmacodynamics and
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Luo, Huilong, Lucie Chevillard, Frank Bellivier, et al. "The role of brain barriers in the neurokinetics and pharmacodynamics of lithium." Pharmacological Research 166 (April 2021): 105480. http://dx.doi.org/10.1016/j.phrs.2021.105480.

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Mosin Kadr, Jyoti Perke. "Effect of Self-instructional Module on Knowledge Regarding Lithium Carbonate Therapy among the Staff Nurses in Selected Psychiatric Institutions of Mumbai City." Innovational Journal of Nursing and Healthcare 09, no. 04 (2023): 68–72. http://dx.doi.org/10.31690/ijnh.2023.v09i04.015.

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Introduction: Mental illness affects one in every eleven individuals in India, or approximately 50 million Indians are afflicted with psychiatric disorders. Approximately one in ten thousand individuals with psychiatric disorders will experience mood disorders at some point in their lives. Arecent NICE guideline from 2014 designates lithium as the initial maintenance treatment for bipolar affective disorder. Materials and Methods: A quasi-experimental, one group pre-test, post-test design has been adopted to assess the effectiveness of selfinstructional module (SIM) on knowledge, among the sta
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Kozlovsky, V. L., and A. S. Zbrodina. "Valproic acid: historical background and prospects for use in urgent psychiatric practice." Medical alphabet, no. 2 (March 28, 2025): 52–55. https://doi.org/10.33667/2078-5631-2025-2-52-55.

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The expansion of indications for the use of valproic acid (VK) has been noted since the end of the 20th century. On the one hand, this is due to the pharmacodynamics of the drug and the favorable profile of its clinical action, and on the other hand, the emergence of modern dosage forms that determine the ease of use. By analogy with carbamazepine, the therapeutic activity of VK began to be studied in mental disorders. Along with the thymostabilizing effect similar to lithium, VK began to be used for the treatment of not only affective fluctuations, but also for the prevention of secondary exa
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Chen, Grace, George G. Nomikos, John Affinito, and Zhen Zhao. "Lack of Effect of Vortioxetine on the Pharmacokinetics and Pharmacodynamics of Ethanol, Diazepam, and Lithium." Clinical Pharmacokinetics 55, no. 9 (2016): 1115–27. http://dx.doi.org/10.1007/s40262-016-0389-0.

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Brier, M. E., R. A. Brier, F. C. Luft, and G. R. Aronoff. "Kinetics and pharmacodynamics of atrial natriuretic peptide and lithium clearance in the isolated perfused rat kidney." Journal of Pharmacology and Experimental Therapeutics 243, no. 3 (1987): 868–73. https://doi.org/10.1016/s0022-3565(25)39302-x.

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Abdyrakhmanova, A. K., N. A. Shnayder, N. G. Neznanov, and R. F. Nasyrova. "Pharmacogenetics of quetiapine." Personalized Psychiatry and Neurology 1, no. 1 (2021): 73–83. http://dx.doi.org/10.52667/2712-9179-2021-1-1-73-83.

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(1) Introduction: Quetiapine (QTP) is a dibenzothiazepine derivative, a second generation antipsychotic (AP), which is structurally similar to clozapine. The main indications for use are schizophrenia and depressive disorder. Under manic episodes in bipolar disorder can be used alone or in combination with lithium. The frequency of prescribing QTP is on average 11,987 per 100,000 population, with a positive trend in dynamics: a growth rate of more than 800% within the period 2002 to 2017.(2) Purpose: The review of studies of pharmacogenetic pharmacokinetic and pharmacogenetic pharmacodynamic m
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Dissertations / Theses on the topic "Lithium pharmacodynamics"

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Faure, Jean-Baptiste. "Effets métaboliques et comportementaux à long terme de l'administration précoce de carisbamate dans le modèle d'épilepsie "lithium-pilocarpine" chez le rat." Thesis, Strasbourg, 2014. http://www.theses.fr/2014STRAJ004/document.

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L’épilepsie du lobe temporal (ELT) est une pathologie neurologique sévère dont le fort taux de pharmacorésistance nécessite de nouveaux traitements. Le modèle lithium-pilocarpine modélise les caractéristiques et le développement de l’ELT. L’administration du carisbamate au début de l’épileptogenèse empêche l’apparition de l’ELT dans une sous-population de rats et la remplace par une épilepsie de type absence (ETA). L’évaluation cognitive effectuée durant la phase chronique a permis de distinguer les deux sous-populations : le groupe épilepsie de type absence ne développe pas le déficit cogniti
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Books on the topic "Lithium pharmacodynamics"

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Neil, Johnson F., ed. Lithium and the endocrine system. Karger, 1988.

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Jolly, Elaine, Andrew Fry, and Afzal Chaudhry, eds. Clinical pharmacology and therapeutics. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199230457.003.0005.

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Chapter 5 covers the basic science and clinical topics relating to clinical pharmacology and therapeutics which trainees are required to learn as part of their basic training and demonstrate in the MRCP. It covers pharmacodynamics, pharmacokinetics, drug metabolism and prescribing in special circumstances, drug interactions, adverse drug reactions, drug development, paracetamol poisoning, salicylate poisoning, lithium toxicity, digoxin toxicity, carbon monoxide poisoning, ethylene glycol poisoning, and tricyclic antidepressant poisoning.
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Fabbri, Chiara, and Alessandro Serretti. The treatment of bipolar disorder in the era of personalized medicine: myth or promise? Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0031.

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Bipolar disorder (BD) is a chronic disease associated with high personal and socio-economic burden. Genetics accounts for 20–95% of variability in central nervous system drug disposition and pharmacodynamics, thus genetic markers are considered a promising way to develop tailored treatments and improve the prognosis of the disease. Among mood stabilizers, lithium response was the most investigated phenotype and the most replicated genes are involved in synaptic plasticity (BDNF), serotonergic (SLC6A4) and dopaminergic (DRD1) neurotransmission, and second messenger cascades (GSK3B). Relevant ph
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Book chapters on the topic "Lithium pharmacodynamics"

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Simons, Nicole W., and Alexander W. Charney. "Current Pharmacological Treatments for Bipolar Disorder." In Charney and Nestler's Neurobiology of Mental Illness, 6th ed., edited by Alexander W. Charney. Oxford University PressNew York, 2025. https://doi.org/10.1093/med/9780197640654.003.0025.

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Abstract Pharmacological treatments, with and without psychotherapy, are among the primary treatments of bipolar disorder. Treatments differ for the manic and depressed phases of bipolar disorder, as well as for the acute and maintenance phases. Although lithium has historically been the gold standard for treating bipolar disorder since the mid-1900s, a variety of antipsychotics have been widely prescribed since the turn of the 21st century. The 18 currently U.S. Food and Drug Administration–approved pharmacological treatments of bipolar disorder span three pharmacological classifications: moo
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Post, Robert M. "Lithium and related mood stabilizers." In New Oxford Textbook of Psychiatry. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199696758.003.0154.

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Lithium is the paradigmatic mood stabilizer. It is effective in the acute and prophylactic treatment of both mania and, to a lesser magnitude, depression. These characteristics are generally paralleled by the widely accepted anticonvulsant mood stabilizers valproate, carbamazepine (Table 6.2.4.1), and potentially by the less well studied putative mood stabilizers oxcarbazepine, zonisamide, and the dihydropyridine L-type calcium channel blocker nimodipine. In contrast, lamotrigine has a profile of better antidepressant effects acutely and prophylactically than antimanic effects. Having grouped
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