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Journal articles on the topic 'Liver Cancer Diagnosis'

Author: Grafiati

Published: 4 June 2021

Last updated: 30 January 2023

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1

TODA, GOTARO. "Diagnosis and treatment of liver cancer." Nihon Naika Gakkai Zasshi 87, no. 9 (1998): 1848–55. http://dx.doi.org/10.2169/naika.87.1848.

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2

Punin, K. V. "Syphilis and liver cancer." Kazan medical journal 29, no. 1-2 (November 19, 2021): 48–56. http://dx.doi.org/10.17816/kazmj80418.

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The physician-therapist constantly has to meet with two diseases, the clinical picture of which is extremely similar to one another, but the prognosis of which, in most cases, is sharply different, if at the time the diagnosis is made and the appropriate treatment is undertaken. I mean here liver cancer and its tertiary luetic changes. Differential diagnosis of these two diseases is sometimes difficult even for a well-equipped clinical institution, represented by sufficiently large therapeutic forces, especially since it may not be within the power of a young district doctor.

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3

Komemushi, Atsushi, Noboru Tanigawa, Chizu Koreeda, Shuji Kariya, Rie Yagi, Sachi Nakatani, Satoshi Suzuki, et al. "Recent diagnosis and therapy for liver cancer." Journal of Microwave Surgery 29 (2011): 39–43. http://dx.doi.org/10.3380/jmicrowavesurg.29.39.

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4

Hami, H., A. Ayoujil, F. Z. Azzaoui, F. Habib, A. Soulaymani, A. Mokhtari, and A. Quyou. "Liver Cancer in Morocco: Diagnosis and Outcome." International Journal of Epidemiology 44, suppl_1 (September 23, 2015): i251. http://dx.doi.org/10.1093/ije/dyv096.462.

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5

Yoshida, Hideo, Haruhiko Yoshida, Shuichiro Shiina, and Masao Omata. "Early liver cancer: concepts, diagnosis, and management." International Journal of Clinical Oncology 10, no. 6 (December 21, 2005): 384–90. http://dx.doi.org/10.1007/s10147-005-0537-2.

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6

Sakamoto, Minoru. "2. Diagnosis and Surveillance of Liver Cancer." Japanese Journal of Radiological Technology 72, no. 1 (2016): 97–105. http://dx.doi.org/10.6009/jjrt.2016_jsrt_72.1.97.

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7

Hatazawa, Jun. "Diagnosis: Liver metastasis of sigmoid colon cancer." Annals of Nuclear Medicine 15, no. 3 (June 2001): 216. http://dx.doi.org/10.1007/bf02987834.

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8

Sada, Yvonne, Eric David, Hashem El-Serag, Hardeep Singh, and Jessica Davila. "Guideline adherence for diagnosis of liver cancer in veterans." Journal of Clinical Oncology 31, no. 31_suppl (November 1, 2013): 89. http://dx.doi.org/10.1200/jco.2013.31.31_suppl.89.

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89 Background: The incidence of hepatocellular cancer (HCC) is rising. Practice guidelines provide the recommended approach for HCC diagnosis, but adherence to diagnostic guidelines is unknown. Methods: In a national sample of veterans with confirmed HCC, we performed a retrospective chart review of patients with cirrhosis and a new liver mass on imaging between 2005 and 2011. Clinical data was used to assess adherence to American Association for the Study of Liver Diseases guidelines. Patients with inadequate data to assess guideline adherence (missing liver mass size, imaging technique, or d

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9

Liu, Da-Hua, Gui-Min Wen, Chang-Liang Song, Li-Jun Ji, and Pu Xia. "Amino acid profiles in the tissue and serum of patients with liver cancer." Open Medicine 17, no. 1 (January 1, 2022): 1797–802. http://dx.doi.org/10.1515/med-2022-0589.

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Abstract Most patients with liver cancer were found late and lost the chance of surgery. Liquid biopsy can monitor the risk of tumor recurrence and metastasis, quickly evaluate the curative effect of tumor treatment, and is conducive to early screening and auxiliary diagnosis of high-risk groups. Amino acid (AA) profiling has been used to the diagnosis and the prognosis for cancers. However, little was known about the profiles of AA of liver cancer. In this study, we used tRNA in Cancer database to analyze the AA levels in liver cancer tissues. Blood samples of patients with liver cancer were

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Guo, Hongyan, and Qingfeng Liu. "Clinical Value of Growth Differentiation Factor 15 Detection in the Diagnosis of Early Liver Cancer Based on Data Mining." BioMed Research International 2022 (November 17, 2022): 1–11. http://dx.doi.org/10.1155/2022/4448075.

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The incidence of liver cancer is increasing year by year, and how to effectively diagnose early-stage liver cancer and improve the survival rate of liver cancer patients has become one of the current research topics of concern. Aiming at this problem, it is of great significance for the diagnosis of early liver cancer. With the in-depth research on the diagnosis of early-stage liver cancer, the research on growth differentiation factor 15 is gradually carried out, and its performance advantages are of great significance to solve the problem of detection and diagnosis of early-stage liver cance

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11

Tønnesen, Jacob, Jannik Pallisgaard, Peter Vibe Rasmussen, Martin H. Ruwald, Morten Lamberts, Nina Nouhravesh, Jarl Strange, Gunnar Hilmar Gislason, and Morten Lock Hansen. "Risk and timing of venous thromboembolism in patients with gastrointestinal cancer: a nationwide Danish cohort study." BMJ Open 13, no. 1 (January 2023): e062768. http://dx.doi.org/10.1136/bmjopen-2022-062768.

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AimsCancer is a well-known risk factor of venous thromboembolism (VTE). Some cancers are believed to be more thrombogenic. The purpose of this study was to investigate the characteristics of patients with incident gastrointestinal cancers (GI) and their associated 1-year risk and timing of venous thromboembolic events and the 1-year mortality.MethodsThis study was a retrospective cohort study. Through Danish nationwide registries, all patients with first-time GI cancer diagnosis from 2008 to 2018 were identified. Incident VTE events were identified within a 1-year follow-up after GI cancer dia

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12

Li, J. "The Experiences of Early Detection, Early Diagnosis and Early Treatment of Cancer in Rural Areas of China." Journal of Global Oncology 4, Supplement 2 (October 1, 2018): 49s. http://dx.doi.org/10.1200/jgo.18.60300.

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Background: The cancers of the lung, liver, stomach, esophagus, colorectum and nasopharynx account for more than 70% of the causes of cancer death, making them the major cancer burdens in China. The early detection and treatment of cancers including lung, liver, stomach, esophagus, colorectum and nasopharynx was supported by the central government special financial transfer payment in the rural areas in 2006-2017. Aim: To improve the efficiency of early diagnosis and early treatment to reduce cancer mortality and incidence in the population in China. Methods: Cancer screening methods developed

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13

Jun, Kong, Leng Tongmin, Gong Jianping, and Tang Maoming. "Clinical research of primary liver cancer mimicking liver abscess." International Surgery Journal 4, no. 3 (February 25, 2017): 1033. http://dx.doi.org/10.18203/2349-2902.isj20170857.

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Background: Aiming at diagnosing at an early stage, minimizing the misdiagnosis rate and improving the prognosis, the author has investigated the clinical characteristics, diagnosis and treatment of primary liver cancer mimicking liver abscess with a summary and discussion.Methods: All of the 11 cases of primary liver cancer mimicking liver abscess, diagnosed during January 2009 to December 2015, were retrospectively viewed in terms of clinical manifestations, laboratory tests, radiological feature, diagnosis and treatment. And statistic analysis was made in all aspects mentioned above with th

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14

Lleo, Ana, Ynto S. de Boer, Rodrigo Liberal, and Massimo Colombo. "The risk of liver cancer in autoimmune liver diseases." Therapeutic Advances in Medical Oncology 11 (January 2019): 175883591986191. http://dx.doi.org/10.1177/1758835919861914.

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Hepatocellular carcinoma (HCC), the dominant primary malignancy of the liver, has almost invariably a fatal outcome that can be averted only by early diagnosis and treatment. While the close association of HCC with chronic viral hepatitis and alcohol abuse has impacted favourably on screening and treatment of this deadly tumour, at the same time it has long obscured the etiologic role of autoimmune liver diseases. Recently, a systematic analysis of 25 published cohorts disclosed a 3.1 × 1000 patients/year incidence of HCC in autoimmune hepatitis patients that tripled in those with cirrhosis. H

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15

Volk, Michael L., and Jorge A. Marrero. "Early detection of liver cancer: Diagnosis and management." Current Gastroenterology Reports 10, no. 1 (February 2008): 60–66. http://dx.doi.org/10.1007/s11894-008-0010-2.

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16

Zhao, Wenxing. "Early diagnosis and precise treatment of hepatocellular carcinoma." E3S Web of Conferences 271 (2021): 03012. http://dx.doi.org/10.1051/e3sconf/202127103012.

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Liver cancer is called the "king of cancer" because of its extremely high mortality rate and lack of effective treatment methods. Effective early diagnosis of liver cancer and advance discovery period of liver cancer can effectively improve the survival rate and life cycle. Early diagnosis can be done by traditional US, CT, AFP level measurement and other methods, or by biological markers such as GPC-3, micro-RNA, and detection of some specific cell signal factors. Precision treatment is often carried out with a personalized treatment plan for the patient and a targeted therapy at the molecula

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17

Ling, Binbing, Lifeng Chen, Qiang Liu, and Jian Yang. "Gene Expression Correlation for Cancer Diagnosis: A Pilot Study." BioMed Research International 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/253804.

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Poor prognosis for late-stage, high-grade, and recurrent cancers has been motivating cancer researchers to search for more efficient biomarkers to identify the onset of cancer. Recent advances in constructing and dynamically analyzing biomolecular networks for different types of cancer have provided a promising novel strategy to detect tumorigenesis and metastasis. The observation of different biomolecular networks associated with normal and cancerous states led us to hypothesize that correlations for gene expressions could serve as valid indicators of early cancer development. In this pilot s

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18

Egorkina, A. B., Yu A. Stepanova, G. G. Karmazanovsky, D. V. Kalinin, and A. V. Zhao. "Advanced lung cancer in combination with liver echinococcosis." Medical Visualization 25, no. 2 (May 18, 2021): 124–32. http://dx.doi.org/10.24835/1607-0763-941.

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Presented clinical case is a rare case of poorly differentiated squamous cell non-keratinizing cancer of the right lung with ingrowth into the diaphragm and liver, metastatic liver damage in combination with recurrent echinococcosis of the liver. Taking into account the epidemiological history, the surgery, the features of radiation imaging and the results of serology in the preoperative period, the diagnosis of “echinococcosis of the liver with spread to the lungs” was made, which turned out to be incorrect. The diagnosis during the surgical operation was changed, but also turned out to be in

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19

Nan, Yuemin, Xiaoyuan Xu, Yanhang Gao, Rongqi Wang, Wengang Li, Ming Yang, Lingdi Liu, et al. "Consensus on the secondary prevention of primary liver cancer." Hepatology International 15, no. 6 (November 30, 2021): 1289–300. http://dx.doi.org/10.1007/s12072-021-10259-7.

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AbstractTo standardize the effective prevention, surveillance, and diagnosis of primary liver cancer, the Chinese Society of Hepatology, Chinese Medical Association, invited clinical experts and methodologists to develop the Consensus on the Secondary Prevention of Primary Liver Cancer, which was based on the clinical and scientific advances on hepatocellular carcinoma. The purpose is to provide a current basis for the prevention, surveillance, and early diagnosis of primary liver cancer in patients with chronic liver diseases.

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20

Lee, Na-Hyun, So Jung Kim, and Jeongeun Hyun. "MicroRNAs Regulating Hippo-YAP Signaling in Liver Cancer." Biomedicines 9, no. 4 (March 30, 2021): 347. http://dx.doi.org/10.3390/biomedicines9040347.

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Liver cancer is one of the most common cancers worldwide, and its prevalence and mortality rate are increasing due to the lack of biomarkers and effective treatments. The Hippo signaling pathway has long been known to control liver size, and genetic depletion of Hippo kinases leads to liver cancer in mice through activation of the downstream effectors yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ). Both YAP and TAZ not only reprogram tumor cells but also alter the tumor microenvironment to exert carcinogenic effects. Therefore, understanding the mecha

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21

&NA;. "Liver cancer breakthrough." Nursing 37, no. 8 (August 2007): 30. http://dx.doi.org/10.1097/01.nurse.0000282701.20608.90.

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22

Taddei, Tamar H., Laura Hunnibell, Anne DeLorenzo, Mirta Rosa, Donna Connery, Donna Vogel, Vijay Garla, Caroline Taylor, and Michal G. Rose. "EMR-linked cancer tracker facilitates lung and liver cancer care." Journal of Clinical Oncology 30, no. 34_suppl (December 1, 2012): 77. http://dx.doi.org/10.1200/jco.2012.30.34_suppl.77.

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77 Background: VA Connecticut Healthcare System has developed a web-based, EMR-linked Cancer Care Tracking System (CCTS) to facilitate tracking and follow-up of patients with imaging abnormalities concerning for lung or liver cancer. The tracker was developed to facilitate the efforts of a multidisciplinary team at the center of which is a cancer navigator. Methods: CCTS was first envisioned in 2007 when VACT hired a care navigator and implemented a radiology coding system to identify potential cancers. This created the need for a tool to process abnormal images and track the clinical steps re

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23

Sindhi, Rakesh, Vinayak Rohan, Andrew Bukowinski, Sameh Tadros, Jean de Ville de Goyet, Louis Rapkin, and Sarangarajan Ranganathan. "Liver Transplantation for Pediatric Liver Cancer." Cancers 12, no. 3 (March 19, 2020): 720. http://dx.doi.org/10.3390/cancers12030720.

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Unresectable hepatocellular carcinoma (HCC) was first removed successfully with total hepatectomy and liver transplantation (LT) in a child over five decades ago. Since then, children with unresectable liver cancer have benefitted greatly from LT and a confluence of several equally important endeavors. Regional and trans-continental collaborations have accelerated the development and standardization of chemotherapy regimens, which provide disease control to enable LT, and also serve as a test of unresectability. In the process, tumor histology, imaging protocols, and tumor staging have also ma

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24

Li, Cong, Guangbing Li, Ruoyu Miao, Xin Lu, Shouxian Zhong, Xinting Sang, Yilei Mao, and Haitao Zhao. "Primary liver cancer presenting as pyogenic liver abscess: Characteristics, diagnosis, and management." Journal of Surgical Oncology 105, no. 7 (September 22, 2011): 687–91. http://dx.doi.org/10.1002/jso.22103.

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25

Chartampilas, Evangelos, Vasileios Rafailidis, Vivian Georgopoulou, Georgios Kalarakis, Adam Hatzidakis, and Panos Prassopoulos. "Current Imaging Diagnosis of Hepatocellular Carcinoma." Cancers 14, no. 16 (August 18, 2022): 3997. http://dx.doi.org/10.3390/cancers14163997.

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Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer related death worldwide. Radiology has traditionally played a central role in HCC management, ranging from screening of high-risk patients to non-invasive diagnosis, as well as the evaluation of treatment response and post-treatment follow-up. From liver ultrasonography with or without contrast to dynamic multiple phased CT and dynamic MRI with diffusion protocols, great progress has been achieved in the last decade. Throughout the last few years, pathological, biological, genetic, and immune-chemical analyses have revealed s

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26

Parinyanitikul, Napa, Laddawan Vajragupta, Naruemon Klaikaew, Boonchoo Sirichindakul, and Virote Sriuranpong. "A benign liver tumor mimics hepatic metastasis from colon cancer." Asian Biomedicine 4, no. 3 (June 1, 2010): 463–67. http://dx.doi.org/10.2478/abm-2010-0057.

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Abstract Background: Liver is the most common distant metastasized organ in advanced colon cancer. Surgical resection of metastatic lesions would offer the best chance of a long-term survival. An accurate diagnosis and evaluation of extent of disease is crucial in the management of liver metastasis. Objective: Report a benign hepatic condition mimicking liver metastasis in a colon cancer patient. Case presentation: A 53-year-old male with an early stage sigmoid colon cancer was treated with sigmoidectomy followed by adjuvant chemotherapy consisting of 5-FU, leucovorin, and oxaliplatin for six

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27

Kong, Yunpeng, Yan Jing, Hongmei Sun, and Shisheng Zhou. "The Diagnostic Value of Contrast-Enhanced Ultrasound and Enhanced CT Combined with Tumor Markers AFP and CA199 in Liver Cancer." Journal of Healthcare Engineering 2022 (February 21, 2022): 1–10. http://dx.doi.org/10.1155/2022/5074571.

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Background. Early screening and diagnosis are of great significance to the treatment and prognosis of patients with liver cancer. This study aims to explore the application value of contrast-enhanced ultrasound and enhanced CT combined with tumor markers alpha-fetoprotein (AFP) and carbohydrate antigen 199 (CA199) in the diagnosis of liver cancer. Methods. Liver cancer group (n = 256), benign disease group (n = 110), and control group (n = 50) participated in this study. The liver cancer and benign disease groups were diagnosed pathologically by contrast-enhanced ultrasound and enhanced CT bef

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Yadav, Sharda, Navid Kashaninejad, and Nam-Trung Nguyen. "RhoA and Rac1 in Liver Cancer Cells: Induction of Overexpression Using Mechanical Stimulation." Micromachines 11, no. 8 (July 28, 2020): 729. http://dx.doi.org/10.3390/mi11080729.

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Liver cancer, especially hepatocellular carcinoma (HCC), is an aggressive disease with an extremely high mortality rate. Unfortunately, no promising markers are currently available for the early diagnosis of this disease. Thus, a reliable biomarker reflecting the early behaviour of the tumour will be valuable for diagnosis and treatment. The Ras homologous (Rho) GTPases, which belong to the small guanosine triphosphate (GTP) binding proteins, have been reported to play an important role in mediating liver cancer based on their important function in cytoskeletal reorganisation. These proteins c

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29

Pan, Xiong-Fei, Meian He, Canqing Yu, Jun Lv, Yu Guo, Zheng Bian, Ling Yang, et al. "Type 2 Diabetes and Risk of Incident Cancer in China: A Prospective Study Among 0.5 Million Chinese Adults." American Journal of Epidemiology 187, no. 7 (January 3, 2018): 1380–91. http://dx.doi.org/10.1093/aje/kwx376.

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Abstract Using data from the China Kadoorie Biobank Study, we conducted a prospective investigation on the association between type 2 diabetes mellitus (T2DM) and cancer risk in Chinese adults. A total of 508,892 participants (mean age = 51.5 (standard deviation, 10.7) years) without prior cancer diagnosis at baseline (2004–2008) were included. We documented 17,463 incident cancer cases during follow-up through December 31, 2013. Participants with T2DM had increased risks of total and certain site-specific cancers; hazard ratios were 1.13 (95% confidence interval (CI): 1.07, 1.19) for total ca

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30

Raptis, Dimitri, and Charles Imber. "Diagnosis and management of primary liver cancer in men." Trends in Urology & Men's Health 13, no. 4 (July 2022): 8–11. http://dx.doi.org/10.1002/tre.865.

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31

Yang, Xien, Quanhong Ou, Weiye Yang, Youming Shi, and Gang Liu. "Diagnosis of liver cancer by FTIR spectra of serum." Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 263 (December 2021): 120181. http://dx.doi.org/10.1016/j.saa.2021.120181.

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32

Wei, Xiao-Cui, Li-Juan Liu, and Fan Zhu. "Exosomes as potential diagnosis and treatment for liver cancer." World Journal of Gastrointestinal Oncology 14, no. 1 (January 15, 2022): 334–47. http://dx.doi.org/10.4251/wjgo.v14.i1.334.

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33

., Vincey Jeba Malar V. "COMPUTER AIDED DIAGNOSIS FOR LIVER CANCER USING STATISTICAL MODEL." International Journal of Research in Engineering and Technology 02, no. 12 (December 25, 2013): 84–89. http://dx.doi.org/10.15623/ijret.2013.0212014.

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34

Yamagishi, S., and M. Ohta. "Diagnosis of anaplastic pancreatic cancer with multiple liver metastases." Postgraduate Medical Journal 74, no. 873 (July 1, 1998): 447. http://dx.doi.org/10.1136/pgmj.74.873.447.

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35

Keegan-Rogers, Valerie, and George Y. Wu. "Immunotargeting in the diagnosis and treatment of liver cancer." Hepatology 9, no. 4 (April 1989): 646–48. http://dx.doi.org/10.1002/hep.1840090421.

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36

Messaoudi, Rim, Faouzi Jaziri, Achraf Mtibaa, Manuel Grand-Brochier, Hawa Mohamed Ali, Ali Amouri, Hela Fourati, Pascal Chabrot, Faiez Gargouri, and Antoine Vacavant. "Ontology-Based Approach for Liver Cancer Diagnosis and Treatment." Journal of Digital Imaging 32, no. 1 (July 31, 2018): 116–30. http://dx.doi.org/10.1007/s10278-018-0115-6.

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37

Fu, Jing, and Hongyang Wang. "Precision diagnosis and treatment of liver cancer in China." Cancer Letters 412 (January 2018): 283–88. http://dx.doi.org/10.1016/j.canlet.2017.10.008.

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38

Fang, Jiwei, and Jianfeng Li. "Research on Classification of Primary Liver Cancer Syndrome Based on Data Mining Technology." Journal of Healthcare Engineering 2022 (January 7, 2022): 1–14. http://dx.doi.org/10.1155/2022/2629509.

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This study is based on the analysis of the status quo of the research on liver cancer syndromes, starting with the clinical objective and true four-diagnosis information of TCM inpatients with primary liver cancer, using computer data mining technology to analyze and summarize the syndrome rules from the bottom to the top. Let the data itself show the essence of liver cancer syndrome. First, with the help of hierarchical cluster analysis, we can understand the general characteristics through the rough preliminary classification of the four-diagnosis information of liver cancer patients. Then,

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39

Zheng, Jianxing, Dongyang Wu, Libing Wang, Fengzhi Qu, Daming Cheng, and Xiaogang Liu. "mir-182-5p Regulates Cell Growth of Liver Cancer via Targeting RCAN1." Gastroenterology Research and Practice 2021 (April 17, 2021): 1–13. http://dx.doi.org/10.1155/2021/6691305.

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Regulator of calcineurin 1 (RCAN1) is an endogenous protein that is involved in the regulation of the occurrence and progression of a variety of cancers, but currently, people know little about its potential mechanism. This study investigated the function and mechanism of RCAN1 and miR-182-5p in liver cancer cells. In this study, reliable data demonstrated that RCAN1 suppressed cell proliferation, migration, invasion, and cell cycle progression of liver cancer. Additionally, the expression of RCAN1 was noted to be regulated by its upstream regulator miR-182-5p, and miR-182-5p was prominently h

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Baj, Jacek, Łukasz Bryliński, Filip Woliński, Michał Granat, Katarzyna Kostelecka, Piotr Duda, Jolanta Flieger, et al. "Biomarkers and Genetic Markers of Hepatocellular Carcinoma and Cholangiocarcinoma—What Do We Already Know." Cancers 14, no. 6 (March 15, 2022): 1493. http://dx.doi.org/10.3390/cancers14061493.

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Hepatocellular carcinoma (HCC) is the most common primary liver cancer with an increasing worldwide mortality rate. Cholangiocarcinoma (CCA) is the second most common primary liver cancer. In both types of cancers, early detection is very important. Biomarkers are a relevant part of diagnosis, enabling non-invasive detection and control of cancer recurrence, as well as in the application of screening tests in high-risk groups. Furthermore, some of these biomarkers are useful in controlling therapy and treatment selection. Detection of some markers presents higher sensitivity and specificity in

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Adamson, E., N. Yussf, and E. Schreiber. "Using Liver Cancer Prevention Messages to Scale up the Diagnosis and Treatment of People Living With Hepatitis B." Journal of Global Oncology 4, Supplement 2 (October 1, 2018): 132s. http://dx.doi.org/10.1200/jgo.18.32800.

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Background and context: Chronic hepatitis B (CHB) is a major public health issue in Australia, affecting an estimated 238,000 people. If not appropriately managed, chronic hepatitis B infection can cause cirrhosis and liver cancer. Liver cancer has the fastest increasing incidence rate of all cancers in Australia, and its survival is among the lowest. To reduce the burden of liver cancer, more people with CHB need to be diagnosed and treated. The majority of people living in Australia with CHB (61%) were born overseas, and research indicates people have low levels of understanding about hepati

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42

Wang, Xiaoping, and Qiaoxia Wang. "Alpha-Fetoprotein and Hepatocellular Carcinoma Immunity." Canadian Journal of Gastroenterology and Hepatology 2018 (2018): 1–8. http://dx.doi.org/10.1155/2018/9049252.

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Hepatocarcinoma is one of the most prevalent gastroenterological cancers in the world with less effective therapy. As an oncofetal antigen and diagnostic marker for liver cancer, alpha-fetoprotein (AFP) possesses a variety of biological functions. Except for its diagnosis in liver cancer, AFP has become a target for liver cancer immunotherapy. Although the immunogenicity of AFP is weak and it could induce the immune escapes through inhibiting the function of dendritic cells, natural killer cells, and T lymphocytes, AFP has attracted more attention in liver cancer immunotherapy. By in vitro mod

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43

Kumar, Sachin, Faizana Fayaz, Faheem Hyder Pottoo, Sakshi Bajaj, Satish Manchanda, and Himangini Bansal. "Nanophytomedicine Based Novel Therapeutic Strategies in Liver Cancer." Current Topics in Medicinal Chemistry 20, no. 22 (October 8, 2020): 1999–2024. http://dx.doi.org/10.2174/1568026619666191114113048.

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Liver cancer is the fifth (6.3% of all cancers i.e., 548,000 cases/year) and ninth (2.8% of all cancers i.e., 244,000 cases/year) most prevalent cancer worldwide in men and women, respectively. Although multiple choices of therapies are offered for Hepatocellular Carcinoma (HCC) like liver resection or transplant, radiofrequency ablation, transarterial chemoembolization, radioembolization, and systemic targeted agent, by the time of diagnosis, most of the cases of HCC are in an advanced stage, which renders therapies like liver transplant or resection and local ablation impractical; and target

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Hao, Xiaoke, Huiyan Luo, Michal Krawczyk, Wei Wei, Wenqiu Wang, Juan Wang, Ken Flagg, et al. "DNA methylation markers for diagnosis and prognosis of common cancers." Proceedings of the National Academy of Sciences 114, no. 28 (June 26, 2017): 7414–19. http://dx.doi.org/10.1073/pnas.1703577114.

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The ability to identify a specific cancer using minimally invasive biopsy holds great promise for improving the diagnosis, treatment selection, and prediction of prognosis in cancer. Using whole-genome methylation data from The Cancer Genome Atlas (TCGA) and machine learning methods, we evaluated the utility of DNA methylation for differentiating tumor tissue and normal tissue for four common cancers (breast, colon, liver, and lung). We identified cancer markers in a training cohort of 1,619 tumor samples and 173 matched adjacent normal tissue samples. We replicated our findings in a separate

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Akuta, Norio, Yusuke Kawamura, Fumitaka Suzuki, Mariko Kobayashi, Yasuji Arase, Satoshi Saitoh, Nozomu Muraishi, et al. "Serum TERT C228T is an important predictor of non-viral liver cancer with fatty liver disease." Hepatology International 16, no. 2 (March 20, 2022): 412–22. http://dx.doi.org/10.1007/s12072-022-10313-y.

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Abstract Background Molecular therapies and precision medicine are expected to be developed for liver cancer based on the diagnosis of DNA somatic alterations. However, it remains unclear whether TERT promoter mutation (TERT C228T) in serum cfDNA is useful for the diagnosis of liver cancer with non-viral fatty liver disease (FLD). Methods This retrospective cohort study examined 258 Japanese patients who had a confirmed diagnosis of primary liver cancer. We investigated the factors associated with TERT C228T and abnormal levels of liver cancer-specific tumor markers (AFP and PIVKAII) in serum

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Zhao, Yuanyu, Ting Chen, Hui Wang, Qiang Xue, Wenyuan Guo, Guoshan Ding, Junfeng Dong, and Junsong Ji. "Influence of Three-Dimensional Visual Reconstruction Technology Combined with Virtual Surgical Planning of CTA Images on Precise Resection of Liver Cancer in Hepatobiliary Surgery." Computational and Mathematical Methods in Medicine 2022 (July 7, 2022): 1–9. http://dx.doi.org/10.1155/2022/4376654.

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Hepatobiliary malignancies, such as hepatocellular carcinoma (HCC) and biliary tract cancers, namely, gallbladder carcinoma and cholangiocarcinoma, are linked to a high rate of morbidity and mortality, depending on the phase of the disease. The intricate hepatobiliary anatomy and the need for accurate peroperative management, especially in patients with advanced liver disease, make these tumors difficult to treat. Surgical resection is a notable therapy for hepatobiliary cancers. Unnecessary or excessive liver excision influences patient rehabilitation, normal liver function, and postoperative

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PELLEGRINO, ANN. "Looking at liver cancer." Nursing 36, no. 10 (October 2006): 52–55. http://dx.doi.org/10.1097/00152193-200610000-00039.

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Nuray Sever, Özlem, Gökmen Aktaş, Başar Aksoy, and Mustafa Yıldırım. "CLINICAL FACTORS PREDICTING RESPONSE TO REGORAFENIB IN METASTATIC COLORECTAL CANCER." Euroasia Journal of Mathematics, Engineering, Natural & Medical Sciences 9, no. 20 (March 25, 2022): 23–27. http://dx.doi.org/10.38065/euroasiaorg.924.

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Colorectal cancer (CRC) is a common disease with high mortality. Regorafenib (Stivarga ®) is an oral small molecule, multiple kinase inhibitor approved worldwide for use in metastatic colorectal cancer. In our study, clinical factors predicting response to regorafenib were investigated. Patients who applied to Gaziantep Medical Park Hospital and Sanko University Medical Faculty Hospital Medical Oncology outpatient clinic between 2010-2021 with the diagnosis of mCRC and using regorafenib were included in the study. Electronic medical records of the patients were reviewed retrospectively. Statis

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Qiu, Wu, Feng Xiao, Xin Yang, Mao Lin Ye, Yu Chi Ming, and Ming Yue Ding. "Application of Fuzzy Enhancement in the Diagnosis of Liver Cancer from Ultrasound Images." Applied Mechanics and Materials 195-196 (August 2012): 493–97. http://dx.doi.org/10.4028/www.scientific.net/amm.195-196.493.

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Fuzzy enhancement is applied in computer aided diagnosis of liver cancer from B mode ultrasound images as a pre-processing procedure in this paper. It was evaluated with three classifiers including K means, back propagation neural network and support vector machine using 25 features from single gray-level statistic, gray-level co-occurrence matrix (GLCM), and gray-level run-length matrix (GLRLM). The results show that the fuzzy enhancement algorithm can improve classification accuracy of normal liver, liver cancer and Hemangioma from B mode ultrasound images for three classifiers. It is proved

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Zhou, Jian, Huichuan Sun, Zheng Wang, Wenming Cong, Jianhua Wang, Mengsu Zeng, Weiping Zhou, et al. "Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma (2019 Edition)." Liver Cancer 9, no. 6 (2020): 682–720. http://dx.doi.org/10.1159/000509424.

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<b><i>Background:</i></b> Primary liver cancer, around 90% are hepatocellular carcinoma in China, is the fourth most common malignancy and the second leading cause of tumor-related death, thereby posing a significant threat to the life and health of the Chinese people. <b><i>Summary:</i></b> Since the publication of <i>Guidelines for Diagnosis and Treatment of Primary Liver Cancer (2017 Edition)</i> in 2018, additional high-quality evidence has emerged with relevance to the diagnosis, staging, and treatment of liver cancer in and outs

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