Academic literature on the topic 'Liver cells Effect of drugs on'

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Journal articles on the topic "Liver cells Effect of drugs on"

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HATANO, MOTOHISA. "Studies on free liver cells of rats. Effect of various drugs." Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 18, no. 1 (1987): 87–88. http://dx.doi.org/10.3999/jscpt.18.87.

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Rashid, M. S., Faheem Hadi, Zoya Muzaffar, H. M. Asif, Naveed Akhtar, Memoona Zahra, Maqbool, L. Sumreen, T. Shamim, and A. Malik. "Cytotoxic Effect of Kigelia Africana Plant Extracts on Liver Cancer Cells." Pakistan Journal of Medical and Health Sciences 16, no. 10 (October 30, 2022): 68–71. http://dx.doi.org/10.53350/pjmhs22161068.

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Background: Various medicinal plants have much efficacious value as treatment of many fatal conditions including cancer. Kigelia africana has known therapeutic efficacy in different ailments and has been used as traditional medicine since ages. Aim: To evaluate anticancer property of any drug or plant extract including HepG2 cell line. Methodology: Anticancer activity of n-hexane and ethanolic extracts of Kigelia africana was checked. IC50 was evaluated via MTT assay, crystal violet assay was performed to check the viability of cells and trypan blue assay to count dead cells. Furthermore, muse
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Ting, Liu, Liu Juan, and Yang Jian Qiong. "Effective Components of Hepatoprotective Drugs." Applied Mechanics and Materials 633-634 (September 2014): 533–36. http://dx.doi.org/10.4028/www.scientific.net/amm.633-634.533.

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Pathological changes in animal models of autoimmune hepatitis and liver cells were similar to the mechanism of injury and viral hepatitis, the thesis of the active component of several common liver substances studied, wild chrysanthemum extract has anti-bacterial, anti-viral, pharmacological effects such as anti-inflammatory and immune liver and nerve protection, Dicliptera polysaccharide with excellent hepatoprotective activity of the liver that can be used as an adjunct to clinical medicine. Introduction
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Li, Rui, Chengyong Dong, Keqiu Jiang, Rui Sun, Yang Zhou, Zeli Yin, Jiaxin Lv, Junlin Zhang, Qi Wang, and Liming Wang. "Rab27B enhances drug resistance in hepatocellular carcinoma by promoting exosome-mediated drug efflux." Carcinogenesis 41, no. 11 (May 11, 2020): 1583–91. http://dx.doi.org/10.1093/carcin/bgaa029.

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Abstract Liver cancer is a major threat to human life and health, and chemotherapy has been the standard non-surgical treatment for liver cancer. However, the emergence of drug resistance of liver cancer cells has hindered the therapeutic effect of chemical drugs. The discovery of exosomes has provided new insights into the mechanisms underlying tumour cell resistance. In this study, we aimed to determine the proteins associated with drug resistance in tumour cells and to elucidate the underlying mechanisms. We found that Rab27B expression in drug (5-fluorouracil, 5Fu)-resistant Bel7402 (Bel/5
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Renovaldi, Dede, and Abdul Khalik Adam. "Potential of Sweet Basil (Ocimum basilicum) as a Hepatoprotector Agent for Liver Injury Related to Drugs." Muhammadiyah Medical Journal 1, no. 2 (November 16, 2020): 63. http://dx.doi.org/10.24853/mmj.1.2.63-68.

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The use of drugs is one of the most common causes of liver injury, because the liver is the main organ that metabolizes drugs. Little is currently done if there is a liver injury due to the hepatotoxic side effects of a drug. Herbal plants have active natural compounds that have pharmacological effects so they are widely used as alternative treatments. Sweet basil (Ocimum basilicum) is one of the most cultivated plants in Asia. Studies on the use of Ocimum basilicum in medicine have been carried out, one of which is the hepatoprotector effect. Studies indicate that Ocimum basilicum is rich in
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Renovaldi, Dede, and Abdul Khalik Adam. "Potential of Sweet Basil (Ocimum basilicum) as a Hepatoprotector Agent for Liver Injury Related to Drugs." Muhammadiyah Medical Journal 1, no. 2 (November 16, 2020): 21. http://dx.doi.org/10.24853/mmj.1.2.21-26.

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The use of drugs is one of the most common causes of liver injury, because the liver is the main organ that metabolizes drugs. Little is currently done if there is a liver injury due to the hepatotoxic side effects of a drug. Herbal plants have active natural compounds that have pharmacological effects so they are widely used as alternative treatments. Sweet basil (Ocimum basilicum) is one of the most cultivated plants in Asia. Studies on the use of Ocimum basilicum in medicine have been carried out, one of which is the hepatoprotector effect. Studies indicate that Ocimum basilicum is rich in
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Liao, Wei, Yan Tang, Zhengcui Hu, Chunyan Wang, Yi Chen, Yi Zhang, and Wenhan Fan. "Preparation of Galactosyl Nanoparticles and Their Targeting Efficiency to Hepatocellular Carcinoma." Journal of Nanoscience and Nanotechnology 21, no. 2 (February 1, 2021): 987–94. http://dx.doi.org/10.1166/jnn.2021.18666.

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Liver diseases seriously endanger people’s physical health, especially liver cancer, and its morbidity and mortality have increased year by year. The reason why liver cancer is difficult to cure is that in addition to the low lethality of cancer drugs to cancer cells, another important factor is that the drugs do not have liver targeting, and there is no way to efficiently deliver anti-cancer drugs to the liver lesions. Hepatocytes can specifically recognize galactose, therefore the galactosyl liver-targeted drug carrier can deliver the drug to the liver in a targeted manner, so that the drug
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ÖNAL, Müge Gülcihan. "A New Approach: Treatment with Sodium Vanadate and Cisplatin Combination for Human Hepatocellular Carcinoma." Proceedings 40, no. 1 (December 25, 2019): 14. http://dx.doi.org/10.3390/proceedings2019040014.

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The most common primary liver malignancy is hepatocellular carcinoma. Various chemotherapy drugs are used for treatment. These drugs have high toxicity to liver tissue. More effective, less toxic options should be preferred for treatment. The aim of this study is to investigate the cytotoxic effect of cisplatin and sodium vanadate combination (NaV) in hepatocellular carcinoma. The hepatocellular cancer cell line (HepG2) was used in this study. Increased concentration of cisplatin and a selected concentration of sodium vanadate were treated to HepG2 cells for 24- and 72-hours incubation times.
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Tian, Shiliu, Rui Su, Ke Wu, Xuhan Zhou, Jaydutt V. Vadgama, and Yong Wu. "Diaporine Potentiates the Anticancer Effects of Oxaliplatin and Doxorubicin on Liver Cancer Cells." Journal of Personalized Medicine 12, no. 8 (August 16, 2022): 1318. http://dx.doi.org/10.3390/jpm12081318.

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Recent studies have shown that diaporine, a novel fungal metabolic product, has a strong in vitro and in vivo anticancer effect on human non-small-cell lung and breast cancers. In this study, three human hepatocarcinoma cell lines (HepG2, Hep3B, and Huh7) were used to evaluate the efficacy of diaporine alone and in combination with the standard cytotoxic drugs oxaliplatin and doxorubicin for the treatment of liver cancer. We demonstrated that diaporine, oxaliplatin, and doxorubicin triggered a concentration- and time-dependent decrease in the number of HepG2 cells. Diaporine at a concentration
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Hatta, Fazleen Haslinda Mohd, Ruhil Nadirah Che Omar, Mohd Ikhwan Ismail, Rosmadi Mohd Yusoff, and Mohd Shihabuddin Ahmad Noorden. "Determining the Population Doubling Time of HepG2 and Huh-7 Cells and the Toxic Effect of Dimethyl Sulfoxide (DMSO)." ASM Science Journal 17 (November 7, 2022): 1–5. http://dx.doi.org/10.32802/asmscj.2022.1238.

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Developing cell lines that carry promising qualities closest to human hepatocytes in drug studies is a dream of many research laboratories. About 90% of drugs are metabolised by the liver. Therefore, most drug discovery studies utilise hepatocytes to understand the basic mechanism of the drug’s breakdown. To assure hepatocytes survival, various solvents were tested for their cytotoxicity on the cell line. Since most drugs are weakly soluble in water, they can be dissolved in an aprotic solvent. To obtain accurate results, the requirements of these solvents are biocompatible and non-toxic to th
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Dissertations / Theses on the topic "Liver cells Effect of drugs on"

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Nicholls-Grzemski, Felicity April. "The effect of short-term pretreatment with peroxisome proliferators on the acute toxicity of various toxicants, including paracetamol /." Title page, table of contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phn6158.pdf.

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Weng, Yu-I. "Acute and chronic ethanol effects on liver p42/44 mitogen activated protein kinase." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3036867.

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Gronert, Álvarez Anna Christina [Verfasser], and Hans-Heinrich [Akademischer Betreuer] Wedemeyer. "Regulatory T cells in liver transplantation : phenotypical characterisation and effects of immunosuppressive drugs / Anna Christina Gronert Álvarez. Klinik für Gastroenterologie, Hepatologie und Endokrinologie der Medizinischen Hochschule Hannover. Betreuer: Hans-Heinrich Wedemeyer." Hannover : Bibliothek der Medizinischen Hochschule Hannover, 2014. http://d-nb.info/1050008200/34.

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Eng, Heather Sui-Fong. "Evaluating the use of cryopreserved hepatocytes for the prediction of in vivo hepatic clearance /." See Full Text at OhioLINK ETD Center (Requires Adobe Acrobat Reader for viewing), 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=toledo1091638312.

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Thesis (M.S.P.)--University of Toledo, 2004.<br>Typescript. "A thesis [submitted] as partial fulfillment of the requirements of the Master of Science degree in Pharmaceutical Sciences." Bibliography: leaves 64-68.
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Silberstein, D. J. "The effect of renal failure on the elimination of drugs by the liver." Thesis, University of Leeds, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379649.

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Ngamratanapaiboon, Surachai. "Metabolomics investigations of the effect of drugs on mammalian cells." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/41178/.

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Cell-based metabolomics using LC-MS systemizes the study of the uniqueness of small-molecule metabolite (metabolomes) profiles in cellular processes. Cell-based metabolomics can potentially be used in many applications for the study of biological perturbation from stimulants in cellular pathways. The advantages of cell-based metabolomics include ease of control and interpretation when compared to the study of human subjects and animal models. Furthermore, this method can decrease some highly challenging problems that occur in genomics, transcriptomics and proteomics. Nowadays, cell culture in
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Abumansour, Hamza M. A. "Quantitative pharmacoproteomics investigation of anti-cancer drugs in mouse : development and optimisation of proteomics workflows for evaluating the effect of anti-cancer drugs on mouse liver." Thesis, University of Bradford, 2016. http://hdl.handle.net/10454/15724.

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Minimizing anti-cancer drug toxicity is a major challenge for the pharmaceutical industry. Toxicity is most frequently due to either the direct interaction of the drug on previously unidentified targets or its conversion to metabolites by drug metabolizing enzymes (e.g. CYP450 enzymes) that cause cellular, tissue or organ damage. Pharmacoproteomics is beginning to take a central role in studying changes in protein expression corresponding to drug administration, the results of which, inform about the mode of action, toxicity, and resistance in pre-clinical and clinical stages of drug developme
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Teng, Shuzhi, and 滕曙智. "Hepatocellular injury induced by endotoxin and galactosamine." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31241037.

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Kassahun, Kelem. "Mechanistic studies of valproic acid hepatotoxicity : identification and characterization of thiol conjugates." Thesis, University of British Columbia, 1991. http://hdl.handle.net/2429/30831.

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The severe hepatotoxicity of the antiepileptic drug valproic acid (VPA) is believed to be mediated through chemically reactive metabolites. The monounsaturated metabolite 4-ene VPA is steatogenic in the rat, and in a similar fashion to the hepatotoxin 4-pentenoic acid, is thought to be oxidized by mitochondria to a highly reactive α,β-unsaturated ketone, 3-keto-4-ene VPA. The tripeptide thiol, glutathione (GSH), is known to react with a variety of electrophilic compounds that have the potential to interact with cellular macromolecules. The identification and structural characterization of GSH
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Jansen, Robert Walter. "Modified human serum albumins as carriers for the specific delivery of antiviral drugs to liver- and blood cells." [S.l. : [Groningen : s.n.] ; University of Groningen] [Host], 2008. http://irs.ub.rug.nl/ppn/.

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Books on the topic "Liver cells Effect of drugs on"

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International Symposium on "Liver Cells and Drugs" (1987 Rennes, France). Liver cells and drugs: Proceedings of the International Symposium on Liver Cells and Drugs, held in Rennes on July 7-10, 1987. Paris: Editions INSERM, 1988.

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International Symposium on Liver Cells and Drugs (1987 Rennes, France). Liver cells and drugs =: Cellules hépatiques et médicaments : proceedings of the International Symposium on "Liver cells and drugs" held in Rennes on July 7-10, 1987. London: Libbey, 1988.

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Kenʼichi, Kitani, ed. Liver and aging, 1986: Liver and brain : proceedings of the Third Symposium on Liver and Aging--Liver and Brain, held in Tokyo, Japan on August 20-22, 1986. Amsterdam: Elsevier Science Publishers, 1986.

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Neil, Kaplowitz, and DeLeve Laurie D. 1955-, eds. Drug-induced liver disease. New York: Marcel Dekker, 2003.

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International, Symposium on Hepatology and Clinical Pharmacology "Liver and Drugs" (1st 1994 Bratislava Slovakia). Liver and drugs '94: Proceedings of the 1st International Symposium on Hepatology and Clinical Pharmacology "Liver and Drugs", Bratislava, Slovakia, November 24-26, 1994. Bratislava, Slovak Republic: Liver and Drug Foundation, 1995.

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Convegno medico di informazione epatologica (4th 1986 Cormons, Italy). Fegato e farmaci: Atti del IV Convegno annuale di informazione epatologica, Cormons, 28 giugno 1986. [Padova]: Istituto di medicina interna dell'Università di Padova, Cattedra di patologia medica I, 1986.

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D, T͡Syrenzhapova O., Shantanova L. N, and Nikolaev S. M, eds. Optimizat͡sii͡a adaptivnykh prot͡sessov organizma. Moskva: "Nauka", 1990.

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Ballachey, Brenda Elizabeth. Comparison of Cytochrome P450 1A induction in blood and liver cells of sea otters. Anchorage, Alaska: Exxon Valdez Oil Spill Trustee Council, 2003.

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Advances in mitochondrial medicine. Dordrecht: Springer Verlag, 2012.

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W, Wang Kevin K., and Yuen Po-Wai, eds. Calpain: Pharmacology and toxicology of calcium-dependent protease. Philadelphia, PA: Taylor & Francis, 1999.

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Book chapters on the topic "Liver cells Effect of drugs on"

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Van Bezooijen, C. F. A., G. J. M. J. Horbach, and C. F. Hollander. "The Effect of Age on Rat Liver Drug Metabolism." In Drugs and Aging, 45–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70788-9_4.

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Neuman, M., R. Cameron, and N. Shear. "Drug-Induced Apoptosis of Skin Cells and Liver." In Apoptosis and Its Modulation by Drugs, 343–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-57075-9_13.

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Kostner, G. M. "The Interaction of Lp(A) with Liver Cells: Implications for Lipid Lowering Therapy." In Drugs Affecting Lipid Metabolism, 151–59. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1703-6_21.

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Geerts, Albert, Luc Bouwens, Ronald De Zanger, Hans Van Bossuyt, and Eddie Wisse. "The Structure of Different Types of Liver Cells in Relation to Uptake and Exchange Processes." In Targeting of Drugs, 1–14. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5574-8_1.

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Lindner, J., R. Eurich, K. Grasedyck, P. Schmiegelow, and A. Nüssgen. "Age-Dependent Differences of the Therapeutic Effect on Experimental Liver Fibrosis and Cirrhosis (Morphology and Biochemistry)." In Drugs and Aging, 80–103. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70788-9_7.

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Lirussi, F., and L. Okolicsanyi. "The Effect of Drugs on Liver Function and Biliary Secretion." In Biochemical Pharmacology as an Approach to Gastrointestinal Disorders, 239–47. Dordrecht: Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-011-5390-4_19.

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Scherphof, Gerrit L., Toss Daemen, Hans Derksen, George Lázár, Halbe H. Spanjer, and Frits H. Roerdink. "In Vivo Uptake and Processing of Liposomes by Parenchymal and Non-Parenchymal Liver Cells; Application to Immunotherapeutic Treatment of Hepatic Metastases." In Targeting of Drugs, 109–20. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5574-8_10.

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Dini, L. "Clearance of Apoptotic Lymphocytes by Human Kupffer Cells. Phagocytosis of Apoptotic Cells in the Liver: Role of Lectin Receptors and Therapeutic Advantages." In Apoptosis and Its Modulation by Drugs, 319–41. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-57075-9_12.

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Rossaro, L., S. R. Dowd, V. Simplaceanu, R. Naccarato, D. H. Van Thiel, and C. Ho. "Effect of FK 506 and Cyclosporins on Model Membranes Studied by Nuclear Magnetic Resonance Spectroscopy." In Drugs and the Liver: High Risk Patients and Transplantation, 177–84. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1994-8_29.

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Ansari, Nariman, Stefanie Hardung, Katharina Hötte, Stefanie Rakel, Patrick Antonietti, Donat Kögel, Ernst H. K. Stelzer, and Francesco Pampaloni. "Quantifying the Autophagy-Triggering Effects of Drugs in Cell Spheroids with Live Fluorescence Microscopy." In Methods in Molecular Biology, 19–29. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0856-1_3.

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Conference papers on the topic "Liver cells Effect of drugs on"

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Ma, Liang, Jeremy Barker, Changchun Zhou, Biaoyang Lin, and Wei Li. "A Perfused Two-Chamber System for Anticancer Drug Screening." In ASME 2010 International Manufacturing Science and Engineering Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/msec2010-34326.

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A cell culture microfluidic device has been developed to test the cytotoxicity of anticancer drugs while reproducing multi-organ interactions in vitro. Cells were cultured in separate chambers representing the liver and tumor. The two chambers were connected through a channel to mimick the blood flow. Glioblastoma (GBM) cancer cells (M059K) and hepatoma cells (HepG2) were cultured in the tumor and the liver chambers, respectively. The cytotoxic effect of cancer treatment drug Temolozomide (TMZ) was tested using this two chamber system. The experimental results showed that with the liver cells,
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Tourlomousis, Filippos, and Robert C. Chang. "Computational Modeling of 3D Printed Tissue-on-a-Chip Microfluidic Devices as Drug Screening Platforms." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-38454.

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Physiological tissue-on-a-chip technology is enabled by adapting microfluidics to create micro scale drug screening platforms that replicate the complex drug transport and reaction processes in the human liver. The ability to incorporate three-dimensional (3d) tissue models using layered fabrication approaches into devices that can be perfused with drugs offer an optimal analog of the in vivo scenario. The dynamic nature of such in vitro metabolism models demands reliable numerical tools to determine the optimum tissue fabrication process, flow, material, and geometric parameters for the most
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Tourlomousis, Filippos, and Robert C. Chang. "2D and 3D Multiscale Computational Modeling of Dynamic Microorgan Devices as Drug Screening Platforms." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-52734.

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The ability to incorporate three-dimensional (3D) hepatocyte-laden hydrogel constructs using layered fabrication approaches into devices that can be perfused with drugs enables the creation of dynamic microorgan devices (DMDs) that offer an optimal analog of the in vivo liver metabolism scenario. The dynamic nature of such in vitro metabolism models demands reliable numerical tools to determine the optimum process, material, and geometric parameters for the most effective metabolic conversion of the perfused drug into the liver microenvironment. However, there is a current lack of literature t
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Lin, Mei, Ziyu Wang, and Dongsheng Zhang. "Cytotoxic Effect of As2S3 Nanoparticles on Liver Cancer Cells." In 2006 1st IEEE International Conference on Nano/Micro Engineered and Molecular Systems. IEEE, 2006. http://dx.doi.org/10.1109/nems.2006.334566.

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Помыткина, Татьяна Евгеньевна, Анастасия Андреевна Холзенева, and Екатерина Владимировна Копытова. "TREATMENT OF LIVER CIRRHOSIS IN OUTPATIENT CONDITIONS." In Psychology, Sports science and Medicine (Психология. Спорт. Здравоохранение): сборник статей международной научной конференции (Санкт-Петербург, Октябрь 2022). Crossref, 2022. http://dx.doi.org/10.37539/221030.2022.81.26.005.

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В статье исследуется применение максимальных доз препаратов, после отсутствия эффекта от минимальных и средних дозировок лекарственных препаратов у пациента с идиопатическим циррозом печени. The article examines the use of maximum doses of drugs, after the absence of the effect of minimum and average dosages of drugs in a patient with idiopathic cirrhosis of the liver.
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Tryndyak, Volodymyr, Iryna Kindrat, Brigit McDannell, Frederick A. Beland, and Igor P. Pogribny. "Abstract 5887: A microRNA signature panel predicts differential sensitivity of liver cancer cells to chemotherapeutic drugs." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-5887.

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Alexopoulos, L. G., I. N. Melas, A. D. Chairakaki, J. Saez-Rodriguez, and A. Mitsos. "Construction of signaling pathways and identification of drug effects on the liver cancer cell HepG2." In 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2010). IEEE, 2010. http://dx.doi.org/10.1109/iembs.2010.5626246.

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Tamiya, Nobuyo, Shigekuni Hosogi, Takashi Nakahari, Yoshinori Marunaka, and Koichi Takayama. "The effect of anticancer drugs on mucociliary clearance of bronchial ciliary cells in mice." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa4261.

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Hansen, J. B., J. O. Olsen, L. Wilagård, and B. Østerud. "THE EFFECT OF COD LIVER OIL INTAKE ON THE STIMULATION OF BLOOD CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643406.

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In an in vitro model, stimulation of blood cells with a low concentration of lipopolysaccharides (LPS) revealed differences between women and men that possibly could be an explanation to why young women have less coronary heart disease than men (see abstract Hansen et al. “A model to--”).This model was also used to study the effect of intake of cod liver oil (CLO). 40 students (20 men and 20 women) were tested followed by an intake of 25 ml CLO daily for 2 months by 20 of the students.Heparinized blood samples were incubated with 2 ng LPS/ ml for 2 hours followed by isolation of plasma for thr
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Valle, Blanca L., Theresa D'Souza, Kevin G. Becker, William H. Wood, Robert P. Wersto, and Patrice J. Morin. "Abstract C96: The effect of non‐steroidal anti‐inflammatory drugs (NSAIDs) in ovarian cancer cells." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Nov 15-19, 2009; Boston, MA. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/1535-7163.targ-09-c96.

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Reports on the topic "Liver cells Effect of drugs on"

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He, zhe, liwei Xing, ming He, yuhuan Sun, jinlong Xu, and rong Zhao. Effect of Acupuncture on Mammary Gland Hyperplasia (MGH): a Bayesian network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2022. http://dx.doi.org/10.37766/inplasy2022.9.0058.

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Review question / Objective: This review aims at conducting a network meta-analysis to assess the potential therapeutic effectiveness and safety of acupuncture therapy for the treatment of MGH. Condition being studied: MGH is a benign breast disease caused by excessive growth of mammary duct epithelial cells and interstitial fibers. Its prevalence rate among women of childbearing age is about 13.5-42%, accounting for 99.3% of the total number of patients with breast related diseases, and its possibility of developing breast cancer can reach 5-10%. Breast hyperplasia can cause clinical symptoms
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Elmann, Anat, Orly Lazarov, Joel Kashman, and Rivka Ofir. therapeutic potential of a desert plant and its active compounds for Alzheimer's Disease. United States Department of Agriculture, March 2015. http://dx.doi.org/10.32747/2015.7597913.bard.

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We chose to focus our investigations on the effect of the active forms, TTF and AcA, rather than the whole (crude) extract. 1. To establish cultivation program designed to develop lead cultivar/s (which will be selected from the different Af accessions) with the highest yield of the active compounds TTF and/or achillolide A (AcA). These cultivar/s will be the source for the purification of large amounts of the active compounds when needed in the future for functional foods/drug development. This task was completed. 2. To determine the effect of the Af extract, TTF and AcA on neuronal vulnerabi
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Funkenstein, Bruria, and Cunming Duan. GH-IGF Axis in Sparus aurata: Possible Applications to Genetic Selection. United States Department of Agriculture, November 2000. http://dx.doi.org/10.32747/2000.7580665.bard.

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Many factors affect growth rate in fish: environmental, nutritional, genetics and endogenous (physiological) factors. Endogenous control of growth is very complex and many hormone systems are involved. Nevertheless, it is well accepted that growth hormone (GH) plays a major role in stimulating somatic growth. Although it is now clear that most, if not all, components of the GH-IGF axis exist in fish, we are still far from understanding how fish grow. In our project we used as the experimental system a marine fish, the gilthead sea bream (Sparus aurata), which inhabits lagoons along the Mediter
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Hajarizadeh, Behzad, Jennifer MacLachlan, Benjamin Cowie, and Gregory J. Dore. Population-level interventions to improve the health outcomes of people living with hepatitis B: an Evidence Check brokered by the Sax Institute for the NSW Ministry of Health, 2022. The Sax Institute, August 2022. http://dx.doi.org/10.57022/pxwj3682.

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Background An estimated 292 million people are living with chronic hepatitis B virus (HBV) infection globally, including 223,000 people in Australia. HBV diagnosis and linkage of people living with HBV to clinical care is suboptimal in Australia, with 27% of people living with HBV undiagnosed and 77% not receiving regular HBV clinical care. This systematic review aimed to characterize population-level interventions implemented to enhance all components of HBV care cascade and analyse the effectiveness of interventions. Review questions Question 1: What population-level interventions, programs
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