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Journal articles on the topic 'Liver function tests (LTFs)'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Ayesha, Aftab, Fabha Ali Syeda, Saad Bin Najeeb Shah, et al. "Total Laboratory Automation System in Clinical Biochemistry: Efficient Turnaround Time (TAT) with Prompt, Accurate, Quality Assured Reports for Sustainable Patient Care of Accident and Emergency Department-At a Tertiary Care Hospital." Chemistry Research Journal 8, no. 6 (2023): 114–18. https://doi.org/10.5281/zenodo.11391044.

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<strong>Abstract </strong> <strong>Objective:</strong> To compare and assess benefits of Total Laboratory Automation and its impact on Turnaround Time for Accident and Emergency Department requested chemistry and liver function profile tests. <strong>Materials and Methods</strong>: It’s an observational study based on efficiency of Total lab automation with integrated system of Cobas p471, p512, e801, c503 and p501 in clinical chemistry work flow and achievable targeted TAT of AED requested chemistry profile tests viz, urea, creatinine, electrolytes (tagged as Profile UCE), and Liver fun

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2

MATHEWS, JOHN, JAMES D. SLAVIN, and RICHARD P. SPENCER. "Liver Function Tests." Clinical Nuclear Medicine 5, no. 11 (1986): 344–45. http://dx.doi.org/10.1097/00003072-198605000-00013.

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3

Knight, Joseph A. "Liver Function Tests." Journal of Infusion Nursing 28, no. 2 (2005): 108–17. http://dx.doi.org/10.1097/00129804-200503000-00004.

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4

Smellie, WSA. "Liver function tests." British Journal of Hospital Medicine 70, Sup2 (2009): M26—M28. http://dx.doi.org/10.12968/hmed.2009.70.sup2.38988.

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5

Deal, Allison M., Mihir R. Patel, Brian D. Thorp, Trinitia Y. Cannon, Carol G. Shores, and Adam M. Zanation. "Liver Function Tests." Otolaryngology–Head and Neck Surgery 146, no. 1 (2011): 88–91. http://dx.doi.org/10.1177/0194599811425147.

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6

Laker, M. F. "Liver function tests." BMJ 301, no. 6746 (1990): 250–51. http://dx.doi.org/10.1136/bmj.301.6746.250.

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7

Cramb, R., and C. M. Florkowski. "Liver function tests." BMJ 301, no. 6751 (1990): 557. http://dx.doi.org/10.1136/bmj.301.6751.557-a.

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8

Korones, David N., Marilyn R. Brown, and James Palis. "?Liver function tests? are not always tests of liver function." American Journal of Hematology 66, no. 1 (2000): 46–48. http://dx.doi.org/10.1002/1096-8652(200101)66:1<46::aid-ajh1007>3.0.co;2-o.

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9

Kools, Ann M., and Joseph R. Bloomer. "Abnormal liver function tests." Postgraduate Medicine 81, no. 6 (1987): 45–51. http://dx.doi.org/10.1080/00325481.1987.11699812.

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10

Tang, Ceen-Ming. "Abnormal liver function tests." InnovAiT: Education and inspiration for general practice 12, no. 9 (2019): 507–15. http://dx.doi.org/10.1177/1755738019855092.

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Liver disease is a clinical priority area identified by the RCGP, due to increasing levels of morbidity and mortality. Liver disease causes an estimated 8500 premature deaths in the UK annually, predominantly from a rise in non-alcoholic fatty liver disease, alcohol-related liver disease, and viral hepatitis. There has been a corresponding increase in liver function tests (LFTs) ordered from primary care, often as part of medication reviews or monitoring of chronic disease. GPs will therefore encounter an increasing number of abnormal LFTs in patients asymptomatic of liver disease. This articl

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11

Shapiro, Marc J., Bhueol Chandel, and Arthur E. Baue. "52 LIVER FUNCTION TESTS." Shock 3, no. 5 (1995): 16. http://dx.doi.org/10.1097/00024382-199505000-00053.

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12

Smellie, W. Stuart A., and Stephen D. Ryder. "Biochemical “liver function tests”." BMJ 333, no. 7566 (2006): 481–83. http://dx.doi.org/10.1136/bmj.333.7566.481.

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13

Lisi, Donna M. "Comment: Liver Function Tests." DICP 24, no. 7-8 (1990): 787. http://dx.doi.org/10.1177/106002809002400735.

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14

Yap, Clementine YF, and Tar Choon Aw. "Liver Function Tests (LFTs)." Proceedings of Singapore Healthcare 19, no. 1 (2010): 80–82. http://dx.doi.org/10.1177/201010581001900113.

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15

Welsby, Philip D. "Neglected liver function tests." Postgraduate Medical Journal 92, no. 1089 (2016): 421. http://dx.doi.org/10.1136/postgradmedj-2016-134160.

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16

Renner, Eberhard L. "2 Liver function tests." Baillière's Clinical Gastroenterology 9, no. 4 (1995): 661–77. http://dx.doi.org/10.1016/0950-3528(95)90055-1.

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17

N. Dawood, Muthear, and Nadwa A. J. Mahmood. "Liver function tests in toxoplasmosis." Annals of the College of Medicine, Mosul 38, no. 2 (2012): 68–72. http://dx.doi.org/10.33899/mmed.2012.64600.

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18

Zamor, Philippe J., and Mark W. Russo. "Liver function tests and statins." Current Opinion in Cardiology 26, no. 4 (2011): 338–41. http://dx.doi.org/10.1097/hco.0b013e328347036f.

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19

Ross, Edward A. "ABNORMAL LIVER FUNCTION TESTS: I." Seminars in Dialysis 6, no. 6 (2007): 355–58. http://dx.doi.org/10.1111/j.1525-139x.1993.tb00173.x.

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20

Lim, Victoria S., Michael J. Flanigan, and Linda C. Hochstetler. "ABNORMAL LIVER FUNCTION TESTS: II." Seminars in Dialysis 6, no. 6 (2007): 358–60. http://dx.doi.org/10.1111/j.1525-139x.1993.tb00174.x.

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21

JALAN, R., and P. C. HAYES. "quantitative tests of liver function." Alimentary Pharmacology & Therapeutics 9, no. 3 (2007): 263–70. http://dx.doi.org/10.1111/j.1365-2036.1995.tb00380.x.

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22

Tamburro, Carlo. "Occupational Exposure, Liver Enzymes, and Liver Function Tests." Journal of Occupational & Environmental Medicine 38, no. 4 (1996): 417. http://dx.doi.org/10.1097/00043764-199604000-00022.

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23

Fasoli, Alberto, Edoardo Giannini, Bruno Chiarbonello, et al. "Quantitative liver function tests in chronic liver disease." Digestive and Liver Disease 32 (November 2000): A125. http://dx.doi.org/10.1016/s1590-8658(00)80675-1.

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24

Gopal, Deepak V., and Hugo R. Rosen. "Abnormal findings on liver function tests." Postgraduate Medicine 107, no. 2 (2000): 100–114. http://dx.doi.org/10.3810/pgm.2000.02.869.

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25

V, SowmyaT, and Sowbhagya Lakshmi. "LIVER FUNCTION TESTS PROTOCOL AND SIGNIFICANCE." International Journal of Advanced Research 6, no. 9 (2018): 631–54. http://dx.doi.org/10.21474/ijar01/7720.

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26

Walker, I., L. C. Chappell, and C. Williamson. "Abnormal liver function tests in pregnancy." BMJ 347, oct25 2 (2013): f6055. http://dx.doi.org/10.1136/bmj.f6055.

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27

Tamaskar, Aparna, Sumit Bhargava, Shidhaye R V, and Manorama Singh. "LIVER FUNCTION TESTS AFTER HALOTHANE ANAESTHESIA." Journal of Evolution of Medical and Dental Sciences 3, no. 42 (2014): 10435–42. http://dx.doi.org/10.14260/jemds/2014/3358.

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28

Roderick, P. "Liver function tests: defining what's normal." BMJ 328, no. 7446 (2004): 987. http://dx.doi.org/10.1136/bmj.328.7446.987.

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29

Marwick, Katie F. M., Mark Taylor, and Simon W. Walker. "Antipsychotics and Abnormal Liver Function Tests." Clinical Neuropharmacology 35, no. 5 (2012): 244–53. http://dx.doi.org/10.1097/wnf.0b013e31826818b6.

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30

Pae, Chi-Un. "Antipsychotics and Abnormal Liver Function Tests." Clinical Neuropharmacology 35, no. 6 (2012): 297–98. http://dx.doi.org/10.1097/wnf.0b013e318278feeb.

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31

Ahmed Mudher AL- khaykanee, AG Hamad, and Soura Alaa Hussein. "A review about liver function tests." GSC Biological and Pharmaceutical Sciences 30, no. 1 (2025): 213–17. https://doi.org/10.30574/gscbps.2025.30.1.0023.

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In general, Tests for liver function in the laboratory are those that help diagnose and treat patients with hepatic dysfunction. The liver is responsible for the metabolism of fats., proteins, and carbohydrates. As biochemical markers of liver dysfunction, a few end products of metabolic pathways and enzymes that are extremely sensitive to abnormalities could be employed. Serum bilirubin, Ceruloplasmin, α-fetoprotein, alkaline phosphatase, 5′ nucleotidase, aspartate amino transferase, alanine amino transferase, and gamma glutamyl transferase are a few of the biological. If a patient has one or

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32

Mann, Bruce A. "Predictive Value of Liver Function Tests." Journal of Parenteral and Enteral Nutrition 10, no. 1 (1986): 107–8. http://dx.doi.org/10.1177/014860718601000127.

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33

Devqun, M. S., J. A. Dunbar, J. Hagart, and B. T. Martin. "Alcohol Intake and Liver Function Tests." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 22, no. 1 (1985): 104. http://dx.doi.org/10.1177/000456328502200113.

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34

David, Anna L., Manisha Kotecha, and Joanna C. Girling. "Factors influencing postnatal liver function tests." BJOG: An International Journal of Obstetrics and Gynaecology 107, no. 11 (2000): 1421–26. http://dx.doi.org/10.1111/j.1471-0528.2000.tb11659.x.

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35

Antoljak, N., E. Topic, M. Duvnjak, M. Kastelan, I. Zuntar, and N. Virkic. "Immunologic function tests and liver cirrhosis." Gastroenterology 114 (April 1998): A1205. http://dx.doi.org/10.1016/s0016-5085(98)84888-9.

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36

Moseley, Richard H. "EVALUATION OF ABNORMAL LIVER FUNCTION TESTS." Medical Clinics of North America 80, no. 5 (1996): 887–906. http://dx.doi.org/10.1016/s0025-7125(05)70472-7.

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37

Strasser, Mathew, and Dushyant Singh. "Interpretation of Abnormal Liver Function Tests." Hospital Medicine Clinics 3, no. 1 (2014): e139-e148. http://dx.doi.org/10.1016/j.ehmc.2013.10.003.

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38

Davis, Michael. "DRUGS AND ABNORMAL ???LIVER FUNCTION TESTS???" Adverse Drug Reaction Bulletin 139, no. 1 (1989): 520–23. http://dx.doi.org/10.1097/00012995-198912000-00001.

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39

Roderick, Paul. "Liver function tests: defining what's normal." BMJ 328, no. 7446 (2004): 987.1. http://dx.doi.org/10.1136/bmj.38055.451968.55.

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40

Limdi, J. K. "Evaluation of abnormal liver function tests." Postgraduate Medical Journal 79, no. 932 (2003): 307–12. http://dx.doi.org/10.1136/pmj.79.932.307.

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41

Agrawal, Swastik, Radha K. Dhiman, and Jimmy K. Limdi. "Evaluation of abnormal liver function tests." Postgraduate Medical Journal 92, no. 1086 (2016): 223–34. http://dx.doi.org/10.1136/postgradmedj-2015-133715.

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42

Brown, Robert S. "Thrombocytopenia With Abnormal Liver Function Tests." Clinical Gastroenterology and Hepatology 8, no. 11 (2010): 920–23. http://dx.doi.org/10.1016/j.cgh.2010.05.023.

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43

Sham, Ronald L. "Liver function tests: ?Pugilistic pseudo-relapse?" American Journal of Hematology 68, no. 2 (2001): 135–36. http://dx.doi.org/10.1002/ajh.1168.

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44

Vagvala, Saivenkat H., and Stacy D. O'Connor. "Imaging of abnormal liver function tests." Clinical Liver Disease 11, no. 5 (2018): 128–34. http://dx.doi.org/10.1002/cld.704.

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45

Thapa, B. R., and Anuj Walia. "Liver function tests and their interpretation." Indian Journal of Pediatrics 74, no. 7 (2007): 663–71. http://dx.doi.org/10.1007/s12098-007-0118-7.

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46

Parsons, Graham. "Understanding liver function tests: part 2." Prescriber 34, no. 8-9 (2023): 19–22. http://dx.doi.org/10.1002/psb.2086.

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Liver function tests (LFTs) are useful blood tests to help identify liver disease, but their interpretation can be challenging. Part 2 in this two‐part series on understanding LFTs focuses on a case study of drug‐induced liver injury (DILI) to illustrate how to respond to abnormal LFT results.

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47

Parsons, Graham. "Understanding liver function tests: part 1." Prescriber 34, no. 7 (2023): 19–23. http://dx.doi.org/10.1002/psb.2079.

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48

Cai, Qingxian, Deliang Huang, Hong Yu, et al. "COVID-19: Abnormal liver function tests." Journal of Hepatology 73, no. 3 (2020): 566–74. http://dx.doi.org/10.1016/j.jhep.2020.04.006.

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49

Ahmed, Zohair, Umair Ahmed, Saqib Walayat, et al. "Liver function tests in identifying patients with liver disease." Clinical and Experimental Gastroenterology Volume 11 (August 2018): 301–7. http://dx.doi.org/10.2147/ceg.s160537.

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50

Patel, Bhavin, and Naresh Trivedi. "Alteration of liver function tests in various liver diseases." National Journal of Physiology, Pharmacy and Pharmacology 14, no. 1 (2024): 1. http://dx.doi.org/10.5455/njppp.2023.13.12559202321122023.

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Background: The burden of liver diseases in India has witnessed a significant rise, spurred by factors such as viral hepatitis, alcoholic liver disease, non-alcoholic fatty liver disease, and a spectrum of metabolic and genetic disorders. Liver function tests (LFTs) serve as invaluable tools in the hands of clinicians, offering insights into the dynamic interplay between hepatic health and various disease processes. This study aims to provide a detailed exploration of the alterations in LFTs associated with various liver diseases prevalent in India. Aim and Objectives: (i) To Identify the vari

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