Relevant bibliographies by topics / Liver marker enzymes

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'Liver marker enzymes'

Author: Grafiati
Published: 3 June 2025
Last updated: 20 July 2025

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Journal articles on the topic "Liver marker enzymes"

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Contreras-Zentella, Martha Lucinda, and Rolando Hernández-Muñoz. "Is Liver Enzyme Release Really Associated with Cell Necrosis Induced by Oxidant Stress?" Oxidative Medicine and Cellular Longevity 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/3529149.

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Hepatic diseases are a major concern worldwide. Increased specific plasma enzyme activities are considered diagnostic features for liver diseases, since enzymes are released into the blood compartment following the deterioration of the organ. Release of liver mitochondrial enzymes is considered strong evidence for hepatic necrosis, which is associated with an increased production of ROS, often leading to greater hepatic lipid peroxidation. Lipotoxic mediators and intracellular signals activated Kupffer cells, which provides evidence strongly suggesting the participation of oxidant stress in ac
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Thirugnanam, Siva Sankari, and Subashini Ragunathan. "Hepatoprotective Potential of Esculetin Loaded Chitosan Nanoparticles (ESC-CNPs) in DMBA- Induced Mammary Carcinogenesis in Sprague-Dawley Rats." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 23 (2024): 133–47. https://doi.org/10.56557/upjoz/2024/v45i234694.

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The hepatoprotective effects of Esculetin Loaded Chitosan Nanoparticles (ESC-CNPs) were assessed in this work using a model of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinogenesis. DMBA (25 mg/rat) was injected subcutaneously once close to the mammary gland in Sprague-Dawley rats to cause mammary tumors. To find the ideal dose, several ESC-CNPs concentrations were taken orally. The evaluation of hepatoprotective effects involved the examination of liver marker enzymes (AST, ALT and ALP), enzymatic antioxidants (SOD, CAT, and GPx), and non-enzymatic antioxidants GSH, lipid perox
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Nasiruddin, Mohammad, Irfan Ahmad Khan, and Sayeedul Hasan Arif. "THERAPEUTIC EFFECT OF NYMPHAEA ALBA LINN. FLOWERS AGAINST ISONIAZID-INDUCED HEPATOTOXICITY: AN EXPERIMENTAL STUDY." Asian Journal of Pharmaceutical and Clinical Research 11, no. 5 (2018): 333. http://dx.doi.org/10.22159/ajpcr.2018.v11i5.22830.

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Objective: This study was designed to evaluate the effect of ethanolic extract of Nymphaea alba (NAEE) Linn. flowers on liver marker enzymes, histology, and antioxidant tests against isoniazid (INH)-induced hepatotoxicity in rats.Methods: Wistar albino rats were treated with INH (50 mg/kg) for 28 days to induce hepatotoxicity. Silymarin (100 mg/kg) and NAEE Linn flowers in 200 mg/kg and 400 mg/kg doses, respectively, were used as standard and test drugs. Liver marker enzymes and histological examination of livers were performed to demonstrate the effect of NAEE against INH-induced hepatotoxici
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Danpure, C. J., P. Purkiss, P. R. Jennings, and R. W. E. Watts. "Mitochondrial damage and the subcellular distribution of 2-oxoglutarate:glyoxylate carboligase in normal human and rat liver and in the liver of a patient with primary hyperoxaluria type I." Clinical Science 70, no. 5 (1986): 417–25. http://dx.doi.org/10.1042/cs0700417.

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1. The subcellular distribution of 2-oxoglutarate:glyoxylate carboligase was investigated in a normal human liver, a liver from a patient with pyridoxine-resistant primary hyperoxaluria type I and rat livers subjected to various degrees and types of trauma. 2. On continuous sucrose gradients most of the carboligase fractionated with a peak equilibrium density of 1.19–1.20 g/cm3 and paralleled the distribution of the major peaks of monoamine oxidase, glutamate dehydrogenase and cytochrome oxidase and can be considered to be mitochondrial. Various proportions of the carboligase and mitochondrial
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Suchy, F. J., S. M. Courchene, and B. L. Blitzer. "Taurocholate transport by basolateral plasma membrane vesicles isolated from developing rat liver." American Journal of Physiology-Gastrointestinal and Liver Physiology 248, no. 6 (1985): G648—G654. http://dx.doi.org/10.1152/ajpgi.1985.248.6.g648.

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Taurocholate transport was characterized in basolateral plasma membrane vesicles prepared from the livers of 14-day-old Sprague-Dawley rats using a self-generating Percoll gradient method. Liver plasma membrane protein yield, intravesicular volume, and enrichments of various marker enzymes were similar to those obtained for vesicles from adult rat liver. The basolateral marker enzyme Na+-K+-ATPase was enriched 26-fold in the suckling rat basolateral membrane fraction while the bile canalicular marker enzymes alkaline phosphatase and Mg2+-ATPase were enriched only 3- and 5-fold, respectively. T
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Vijay, Ganesh, and Modi Poornima. "Acute hepatitis in children: A wide clinical spectrum." GSC Biological and Pharmaceutical Sciences 29, no. 2 (2024): 001–7. https://doi.org/10.5281/zenodo.14738302.

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<strong>Introduction</strong>: Acute hepatitis remains an important health problem in children. viral hepatitis particularly hepatitis A remains the most common cause. Nevertheless, other causes such as non A non B hepatitis and mixed infections like enteric fever are other causes particularly in developing countries like India. The spectrum of acute hepatitis is also varied with many atypical presentations in the form of fever along with icterus as presenting features. Use of lab parameters as prognostic markers for development of acute liver failure (ALF) needs further exploration as it can
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S, Karthikeyan, Sureshkumar P, Dinakaran C, Chezhian A, and P. Soundarapandian. "Impact of Ocean Acidification on Marker Enzymes in Asian Seabass Lates Calcarifer (Bloch)." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 23 (2024): 1–9. https://doi.org/10.56557/upjoz/2024/v45i234681.

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Backgrounds: The influence of ocean acidification (OA) is particularly significant on calcifying organisms in marine environment. A possible explanation for acidification-induced changes in fish behaviour is that acidification interferes with marker enzymes in the liver, muscle and brain. Under a range of severe environmental circumstances, marine organisms can be susceptible to oxidative stress and results in the changes in the biochemical components which can be assessed to know the health status of organisms. Aim of the Works: The aim of this study is to observe the impact of ocean acidific
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Koenig, Sarah, Hendryk Aurich, Christian Schneider, et al. "Zonal expression of hepatocytic marker enzymes during liver repopulation." Histochemistry and Cell Biology 128, no. 2 (2007): 105–14. http://dx.doi.org/10.1007/s00418-007-0301-y.

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Gierow, P., and B. Jergil. "Heterogeneity of smooth endoplasmic reticulum from rat liver studied by two-phase partitioning." Biochemical Journal 262, no. 1 (1989): 55–61. http://dx.doi.org/10.1042/bj2620055.

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Smooth microsomal membranes, prepared from rat liver by sucrose-density-gradient centrifugation, were subfractionated by counter-current distribution in an aqueous two-phase system consisting of poly(ethylene glycol) and Dextran T500. A comparison of the distribution curves of marker enzymes, together with theoretically calculated curves, indicated the presence of at least five membrane subfractions, differing in the ratios of the marker enzymes. Glucose-6-phosphatase and arylesterase distributed in one manner, and NADPH-cytochrome c reductase and NADH-ferricyanide reductase in another. Eviden
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Khither, Hanane, Soraya Madoui, Selma Houchi, and Asma Mosbah. "Hepatocurative potential of Thymoquinone against CCl4-Induced Hepatotoxicity: impact on antioxidant defense systems in rat liver and plasma." Brazilian Journal of Animal and Environmental Research 7, no. 4 (2024): e75872. https://doi.org/10.34188/bjaerv7n4-135.

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This study evaluates the oxidative stress markers in a CCl4-induced hepatotoxicity model in rats and explores the hepatoprotective effects of Thymoquinone (TQ). The oxidative stress markers analyzed include Catalase (CAT) and Superoxide Dismutase (SOD) as enzyme markers, and Glutathione (GSH) and Malondialdehyde (MDA) as non-enzyme markers. These markers were assessed in both liver homogenate and plasma levels. CCl4 exposure significantly increased MDA levels, a marker of lipid peroxidation, and decreased GSH, reflecting severe oxidative stress and liver damage. Enzyme activities of CAT and SO
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Dissertations / Theses on the topic "Liver marker enzymes"

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Liu, Wan-tzu, and 劉宛慈. "Metabolite identification of DINP for exposure marker discovery using rat liver metabolizing enzymes and liquid chromatography-mass spectrometry." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/02297215931039280703.

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碩士<br>國立成功大學<br>環境醫學研究所<br>97<br>Di-isononyl phthalates (DINPs), a mixture of widely used plasticizers, contain various isomeric nine-carbon branch chain dialkyl phthalates. The associations between DINPs exposure and antiandrogenic activity, liver, and kidney toxicity in animal experiments were reported. Due to isomeric nature of DINPs, a wide variety of isomeric metabolites is excreted in human urine. So far, few metabolites from DINP isomers are identified for exposure biomonitoring. This study aims to identify DINP metabolites for exposure marker discovery using rat liver metabolizing e
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Li-WenPeng and 彭麗文. "Identification of DiNP metabolites for exposure marker discovery using in vitro metabolism by rat liver enzymes and liquid chromatography-mass spectrometry." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/63037407457311592572.

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Book chapters on the topic "Liver marker enzymes"

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Lachmann, Robin H., and Timothy M. Cox. "Glycogen storage diseases." In Oxford Textbook of Medicine, edited by Timothy M. Cox. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0227.

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Glycogen is a highly branched glucose polymer with a compacted structure found predominantly in liver and muscle. Liver glycogen is important in the maintenance of euglycaemia during fasting; muscle glycogen is an immediate source of glucose for energy production during exercise. Genetic disorders affecting proteins that regulate glycogen metabolism and transport, as well as those which catalyse its biosynthesis and breakdown, cause marked accumulation of glycogen in diverse tissues, and pathological glycogen often has an abnormal macromolecular structure. Depending on the enzyme system involved, diseases of glycogen metabolism principally affect liver and muscle. Clinical features are related to pathological glycogen in tissues and/or failure to release glucose. Glycogen storage is associated with organomegaly and tissue injury. Fasting hypoglycaemia occurs where hepatic breakdown of glycogen is impaired. Glycogen diseases that affect muscle usually present with rhabdomyolysis, exercise intolerance, and muscle pain or weakness. Formerly, diseases of glycogen metabolism were diagnosed by showing excess storage of glycogen in the tissue of interest, accompanied by reduced activity of particular glycogen-metabolizing enzymes. Currently, where available, molecular analysis of genomic DNA is the preferred method for providing a definitive diagnosis. The mainstay of treatment of glycogen diseases affecting the liver is dietary, including pre-emptive management of hypoglycaemia that is readily provoked by fasting. Dietary interventions may also ameliorate some of the glycogen diseases that affect muscle, and weakness and pain after exertion can be improved by graduated exercise programmes in some patients.
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Lee, Christine U., and James F. Glockner. "Case 3.4." In Mayo Clinic Body MRI Case Review, edited by Christine U. Lee and James F. Glockner. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199915705.003.0074.

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32-year-old man with chronic hepatitis C and recent elevation of liver enzyme levels Axial SSFSE (Figure 3.4.1) and fat-suppressed SSFP (Figure 3.4.2) images demonstrate marked diffuse thickening of the gallbladder wall. Hepatitis with marked gallbladder wall thickening Gallbladder wall thickening is associated with a large number of pathologic conditions, including cirrhosis, acute and chronic cholecystitis, ascites, hypoalbuminemia, viral hepatitis, chronic renal failure, and heart failure. The physiologic mechanism responsible for diffuse gallbladder thickening in the presence of systemic or diffuse hepatic disease is uncertain but probably is related to elevated portal venous pressure or decreased intravascular osmotic pressure, or both....
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Van Tong, Hoang, Pham Van Dung, Nguyen Thi Mong Diep, and Nguyen Linh Toan. "Circulating Biomarkers for Early Diagnosis of Hepatocellular Carcinoma." In Hepatocellular Carcinoma - Challenges and Opportunities of a Multidisciplinary Approach [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98483.

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Hepatocellular carcinoma (HCC) is one of the most common malignant tumors, which is also often fatal. An early and accurate diagnosis is a decisive step towards the survival of the patients. Molecular biology improved significantly the prognosis of liver cancers through learned use of tumor markers like proteantigens, cytokines, enzymes, isoenzymes, circulating RNAs, gene mutations and methylations. Nevertheless, much improvement is still achievable and needed in this area, which is crucial in order to make an early diagnosis and monitor the progression of the disease. We present in this review what we believe to be the most relevant data regarding tissue and serum biomarkers related to HCC.
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Proud, Virginia k., and Miriam D. Rosenthal. "HMG-CoA Lyase Deficiency." In Clinical Studies In Medical Biochemistry. Oxford University PressNew York, NY, 2006. http://dx.doi.org/10.1093/oso/9780195147322.003.0020.

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Abstract D.E.C. was a normal female infant (weight 6 lb 4 oz, length 20 inches) born via spontaneous vaginal delivery to an 18-year-old primigravida (first pregnancy). The pregnancy was unplanned and complicated only by maternal use of antidepressants (Zoloft and Depakote) during the first months of gestation. When D.E.C. was 1 month of age, she appeared to have macrocephaly and mild hypotonia; a cranial sector scan was performed and was normal. She was initially breast-fed but was a poor feeder, had gastroesophageal reflux, and gained weight slowly (Fig. 20-1). She sweated profusely when sleeping, and at 4 months of age had hypotonia and poor head control. She was initially hospitalized at 4 months of age during a family vacation. An initial viral illness with low-grade fever and vomiting led to lethargy within 12 h. When she developed generalized seizures, she was taken to the emergency room and admitted. She experienced respiratory decompensation, was intubated, and required ventilator support for 72 h. Laboratory studies demonstrated marked metabolic acidosis with 1100 mol/L; normal 50–200 mol/L). Her liver enzymes were markedly elevated. Her urine contained a number of organic acids, including 3-hydroxyisovaleric acid, 3-methylglutaconic acid, and 3-hydroxy-3-methylglutaric acid, all by-products of leucine catabolism. Plasma amino acid values also suggested a problem in branched-chain amino acid metabolism. Studies with skin fibroblast cultures confirmed a deficiency of 3-hydroxy-3-methylglutaryl (HMG)-CoA-lyase deficiency with zero enzyme activity.
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Cordes, Eugene H. "The conquest of hepatitis C: telaprevir and beyond." In Hallelujah Moments. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190080457.003.0012.

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Taking one pill a day for 8–12 weeks cures 98%–99% of the cases of chronic hepatitis C infections. This is one of the compelling success stories of biomedical research and drug discovery. The discovery of the hepatitis C virus (HCV) as the infective agent opened the doors to unraveling its life cycle and the identification of multiple molecular targets for drug discovery. One such target is HCV protease, an enzyme, among others, essential for virus replication. Several pharmaceutical companies, including Vertex, launched projects to find inhibitors of this enzyme. The Vertex effort overcame multiple problems and created an inhibitor known as telaprevir and marketed as Incivek. Incivek was a remarkable market entry with sales of a billion dollars in its first year. However, the success story was short-lived as Gilead Sciences came up with remarkable combination drugs for Hepatitis C. including Harvoni. Being first with a much improved product is not a guarantee of long-term success.
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Mohamed Nabil Helaly, Ahmed, and Doaa Ghorab. "Perspective Chapter: Topoisomerase 1 and Colo Rectal Carcinoma." In DNA Replication - Mechanisms, Epigenetics, and Gene Therapy Applications [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108988.

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Topoisomerase 1 is the main enzyme playing an important role in relaxing. The supercoiled DNA strands allow the replication fork to transcribe the DNA to RNA and finally control protein production in active and replicating cells. Blocking this essential machinery is a cornerstone mechanism in treating tumors, such as liver, breast, and metastatic colorectal carcinoma. Irinotecan is a topoisomerase inhibitor that blocks the replication ending in DNA break and tumor cell death. This chemotherapy has been successfully used in combination to overcome metastatic colorectal carcinoma. The topoisomerase-1 inhibitor makes a protein DNA complex stuck with the replicating fork creating a single DNA break, unlike topoisomerase-2, which is responsible for double DNA break. This inhibitor is exposed to drug resistance with complex machinery. Drug resistance can occur as a result of altered DNA methylation, changes in topoisomerase expression, histone recombination, or drug export pump. High expression of topoisomerase-1 is a marker of the number of tumors suggesting multiple roles of topoisomerase-1.
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Atkinson, Martin E. "The gastrointestinal system." In Anatomy for Dental Students. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199234462.003.0012.

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The mouth and pharynx are the first parts of the digestive system; they are the principal areas of the gastrointestinal system of interest to dental students and practitioners and are fully described in Chapters 25 and 28. The anatomy of the remainder of the system is described briefly to provide a working knowledge for applications in other aspects of undergraduate dental courses such as nutrition. In essence, the digestive tract is a long convoluted tube illustrated in Figure 6.1. It extends from the mouth, via the pharynx, oesophagus, stomach, small intestine, and large intestine to the anal canal. It is formed along most of its length by longitudinal and circular layers of smooth muscle. It is lined throughout by epithelium which shows marked structural differences from region to region to match different functional requirements of secretion of digestive enzymes, absorption of nutrients, and excretion of waste products. The liver and pancreas are large organs essential to the function of the gastrointestinal system. Food is ingested through the mouth and then prepared for swallowing by being broken up and mixed with saliva by the chewing action of the teeth. Saliva has a major lubricant and minor digestive function. The food is formed into a pellet or bolus and is then swallowed by being moved back by the tongue into the pharynx. Once food is in the pharynx, swallowing becomes a reflex mechanism designed to coordinate contraction of muscles to push the food through the pharynx and oesophagus to the stomach as well as ensuring food and drink do not enter the lower respiratory tract. Swallowing is complex, involving several sets of muscles in the head and neck and is described in more detail in Section 29.1. The passage of food along the remainder of the digestive tract is achieved by regular contractions (peristalsis) of the smooth muscle layers in its walls. The oesophagus is a muscular tube about 25 cm in length. It begins in the neck as a continuation of the pharynx and lies posterior to the trachea as it enters the thorax.
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Gooren, Louis J. G. "Gynaecomastia." In Oxford Textbook of Endocrinology and Diabetes. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.9131.

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Parenchymal and stromal cells with the potential for normal breast development are equally present in prepubertal boys and girls. Men and women do not differ in sensitivity to the hormonal action of sex steroids, and therefore men have the same potential to develop breasts as women. Whether this actually occurs obviously depends on a person’s hormonal milieu. In order to understand the pathophysiology of gynaecomastia it is essential to know that breast tissue is, for its development, under control of both stimulatory hormonal action (oestrogens and progestogens) and inhibitory hormonal action of androgens. Gynaecomastia typically occurs when there is a relative dominance of oestrogenic over androgenic action; many cases of gynaecomastia are not the result of an overproduction of oestrogens per se, but rather due to the failing inhibitory action of androgens (1). In the assessment of gynaecomastia, as much attention must be paid to a potential source of feminizing hormones as to decreased androgen production or interference with the biological action of androgens. Oestrogens stimulate the proliferation and differentiation of parenchymal ductal elements while progesterone supports alveolar development. The biological actions of oestrogens and progesterone do not appear in cases of growth hormone deficiency. Prolactin stimulates the differentiated ducts to produce milk. Testosterone inhibits the growth and differentiation of breast development, probably through an antioestrogenic action (1). Whatever the cause, gynaecomastia shows the same histological developmental pattern. At first, there is florid ductal proliferation, with epithelial hyperplasia and increase in stromal and periductal connective tissue, with increased vascularity and periductal oedema. After approximately one year, there is increased stromal hyalinization, dilation of the ducts, and a marked reduction in epithelial proliferation, a ‘burnt-out’ phase of the condition. The result is inactive fibrotic tissue which no longer responds to endocrine therapy. Gynaecomastia is not an uncommon finding and most cases will not represent a serious medical condition. However, gynaecomastia may signify the presence of a malignancy producing oestrogens, aromatase (the enzyme that converts androgens to oestrogens), or human chorionic gonadotrophin (hCG). Common locations of such tumours are the testis, lungs, liver or the gastrointestinal tract. Consequently, cases of gynaecomastia must be taken seriously and the diagnostic approach must reasonably rule out a malignancy in order to avoid any undue delay in its diagnosis.
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Manzur Sandoval, Daniel, Gustavo Rojas-Velasco, Efren Melano Carranza, et al. "COVID-19 Pathophysiology, Clinical Manifestations, and Drug Treatment." In Moving From COVID-19 Mathematical Models to Vaccine Design: Theory, Practice and Experiences. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815051902122010009.

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COVID-19 is caused by a single-stranded RNA encapsulated betacoronavirus, known as SARS-CoV-2, implicated in the pandemic that started in China in 2019. Viral replication consists of five stages that culminate in the release of the new virion. The exaggerated inflammatory response of COVID-19 is characterized by an elevation of acute phase reactants such as C-reactive protein and ferritin. It is associated with an unfavorable clinical course, intensified&amp;nbsp;by abnormal activation of the protein complex called the inflammasome. When the immune response does not control the virus, lung tissue damage occurs that leads to the massive release of proinflammatory cytokines, producing acute respiratory failure syndrome. Vascular permeability is increased; interaction with coagulation factors develops disseminated intravascular coagulation and multiorgan failure. Up to 33% of cases can be asymptomatic. Clinical manifestations can be mild or severe and involve various organs and systems. Among the most commonly affected are: respiratory, cardiovascular, renal, and hematological and coagulation systems. Among the most representative laboratory data are: elevation of inflammatory markers (CRP, inflammatory cytokines, tumor necrosis factor), high levels of D-Dimer, elevation of troponin I, lymphopenia, thrombocytopenia, alteration of liver enzymes and kidney function. There are risk factors and comorbidities that contribute to the severity of the clinical picture (mainly cardiovascular and metabolic diseases): diabetes mellitus, high blood pressure, obesity, chronic lung diseases, cancer, and chronic kidney failure. There are also other genetic factors associated with the host’s immunopathogenesis and response to SARS COV-2 infection. There are various imaging methods that allow adequate identification and involvement of the pulmonary and cardiovascular systems with great sensitivity and specificity (computed tomography and echocardiography). The pandemic imposed decisions with very little information regarding what may be useful as a therapeutic strategy. This uncertainty applies to the treatment indicated in the prevention phase, as well as to the different stages of severity of the disease. In many cases, treatments were applied without having gone through a trial phase but only with the theoretical support of its probable benefit. However, over time, controlled studies showed that they did not provide any benefit and that they could even have a deleterious effect. Other therapies still in use have shown contradictory results in the different clinical trials where they were tested. Very few therapeutic options have shown undisputable benefit so far. The only ones that can modify the presentation or course of the disease are vaccines, which have also been developed in record time and in controlled trials, and all those that have been approved showed a decrease in the risk of infection and in the risk of presenting a severe manifestation of the disease.&lt;br&gt;
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Conference papers on the topic "Liver marker enzymes"

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Scrobohaci, M. L., L. Drouet, and L. Bertin. "USEFULNESS OF FOLLOW UP OF ANTIGENIC AND FUNCTIONAL LEVELS OF PROTEIN C AND FACTOR VII FOR EARLY DIAGNOSIS OF LIVER TOXICITY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643067.

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Protein C (PC) and Factor VII (F VII) are both vitamino-K dependent factors with similar short half-life. Differential behaviour of both factors in their two expressions was assessed on :- 16 resolutive liver toxicity due to reinforced chemotherapy,- 7 specific liver toxicity of Asparaginase or Bisanthrene- 6 veno-occlusive disease complicating an allogenic bone marrow transplantation- 5 cirrhotic liver insufficiencies- 10 patients submitted to stabilised treatment by oral anticoagulant- 3 families of congenital deficiencies in F VII.In case of congenital deficiency in F VII, both expressions
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Bansal, Rishu, Marika Zhamutashvili, Shweta Tilante, et al. "Diagnostic and Prognostic Analysis of Serological and Bio-chemical Markers in Patients with COVID-19: A Retrospective Study." In Socratic Lectures 8. University of Lubljana Press, 2023. http://dx.doi.org/10.55295/psl.2023.ii2.

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The Coronavirus Disease 2019 (COVID-19) pandemic caused by the Severe Acute Respira-tory Syndrome Coronavirus 2 (SARS-CoV-2) became a challenge globally by affecting mil-lions of people worldwide. Lung injury is the main outcome of COVID-19 infection; how-ever, damage can occur in other organs including the liver. Currently, limited data is available that link underlying liver injury with the severe SARS-CoV-2 infection. This study aimed to investigate the changes in levels of liver enzymes in COVID-19 patients. We con-ducted a retrospective analysis of the medical reports of 90 admitted patie
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"Hepatoprotective Effect of Typhonium flagelliforme against Thioacetamide Induced Liver Cirrhosis in Rats." In 4th International Conference on Biological & Health Sciences (CIC-BIOHS’2022). Cihan University, 2022. http://dx.doi.org/10.24086/biohs2022/paper.643.

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Typhonium flagelliforme (T. flagelliforme) was utilized in outdated medication for handling numerous syndromes. This study aimed to investigate hepatoprotection effects of T. flagelliforme against thioacetamide (TAA) hepatotoxicity in rodents.Thirty rodents arbitrarily separated five clusters. Collection 1 was intraperitoneally injected distilled water thrice /week and fed (p.o) daily with 10% Tween 20 to eight weeks. Collection 2-5 i.p. injected with 200 mg/kg TAA three times thrice per week for 8 weeks and fed 10% Tween 20, 50 mg/kg silymarin, 250 and 500 mg/kg of T. flagelliforme extract da
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Aurousseau, M. H., V. Eclache, and J. Amiral. "CLINICAL RELEVANCE OF D.DIMER AND COAGULATION INHIBITORS IN LIVER CIRRHOSIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643140.

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D.Dimer was measured by a latex agglutination assay and an enzyme immunoassay (E.I.A.) in 25 patients suffering from liver cirrhosis. High levels of D.Dimer (&gt; 500 ng/ml) were found in 13/25 patients’ plasma, by the latex test as well as EIA. Fibrinogen Degradation Products (FDP), measured by the Merskey method, were present in 7/25 samples, whereas soluble fibrin monomer complexes were only detected in 2/25 patients. In both cases, D.Dimer was elevated and FDP were in the normal range. Only one patient developped a Disseminated Intravascular Coagulation (DIC). None of the others had any th
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Husein Ali AL-SAFAR, Ali, and Mohammed Hussein HINDI. "STUDY THE BIOCHEMICAL AND HISTOPATHOLOGICAL CHANGES INDUCE BY CHRONIC METHIMAZOLE EXPOSURE AND PROTECTIVE ROLE OF ARTEMESIA IN FEMALE RATS." In VII. INTERNATIONAL SCIENTIFIC CONGRESSOF PURE,APPLIEDANDTECHNOLOGICAL SCIENCES. Rimar Academy, 2023. http://dx.doi.org/10.47832/minarcongress7-27.

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Sixty white female rats were divided evenly into four target groups to study the effects of methimazole (ME) on biochemical and histological alterations in the rats. The first group received 0.04 mg/kg B.W. of actual (ME) orally every day for 90 days. Also, (ME) with Artemisia(Ar) (2nd) team used to be handled as in first team and at the identical time administered orally for 10% of Artemisia for 90 days. Third (3rd) group was once administrated by way of solely (Art) in the 2nd group. Whereas, fourth set group was once attended and drenched (0.25ml) as manage control. Results examination publ
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Abdulilah ABDULMAWJOOD, Sana, Eman Salem MAHMOUD, and Mohammed I. MAJEED. "INFLAMMATORY MARKERS AND SOME BIOCHEMICAL PARAMETERS IN FEMALE RATS TREATED WITH QUERCETIN." In VI.International Scientific Congress of Pure,Applied and Technological Sciences. Rimar Academy, 2022. http://dx.doi.org/10.47832/minarcongress6-29.

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The objective of this study was to determine whether quercetin, a polyphenol, could protect rats from nitrite's harmful effects. Methodologies: During the course of this investigation, twenty-one albino female rats have been used. The animals were placed in one of the three groups, which each had a total of seven rats. The groups were selected at random. Group, I received water throughout the duration of the experiment and was regarded as the healthy control group. The animals in Group II were given a solution containing 50 milligrams of sodium nitrite per kilogram of body weight via a gavage
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M. Obaid, Reem. "Estimation of Some Physiological Biomarkers Associated with Kidney Failure and Liver Damage in COVID Patients." In XII. International Scientific Congress of Pure, Applied and Technological Sciences. Rimar Academy, 2024. https://doi.org/10.47832/minarcongress12-12.

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A coronavirus referred to by the term SARS-CoV-2 caused the most recent contagion, which was dubbed COVID-19. It has been demonstrated that the Covid-19 viral illness affects a number of systems and organs, including the kidneys and liver. Fever, cough, and dyspnea are the most typical signs of SARS-CoV-2 infection. Methodology look into anomalies in the liver functional testing the serum values of Liver Function Test (LFT) which includes alanine transaminase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) in COVID-19 individuals as well as the usefulness of two markers
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Suzuki, Koji, Yoshihiro Deyashiki, Junji Nishioka, Kazunori Toma, and Shuji Yamamoto. "THE INHIBITOR OF ACTIVATED PROTEIN C: STRUCTURE AND FUNCTION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642963.

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In the final step of protein C pathway, activated protein C (APC) is neutralized with a plasma inhibitor, termed protein C inhibitor (PCI). PCI was first described by Marlar and Griffin (1980) and then isolated from human plasma as a homogeneous form and characterized by the authors (1983). PCI is a single chain glycoprotein with M 57,000 and a plasma concentration of 5 ug/ml. Analysis of a cDNA nucleotide sequence has clarified that a precursor of human PCI consists of a mature protein of 387 amino acid residues (M 43,759) and a signal peptide of 19 amino acid residues. Only one cysteine resi
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Delić-Vujanović, Biljana, Marinković Došenović, Slaviša Đokić, Radojica Đoković, Miloš Petrović, and Mira Majkić. "Variability of laboratory parameters of the metabolic profile in ketosis in cows: Is only comparison with reference values sufficient." In Zbornik radova 26. medunarodni kongres Mediteranske federacije za zdravlje i produkciju preživara - FeMeSPRum. Poljoprivredni fakultet Novi Sad, 2024. http://dx.doi.org/10.5937/femesprumns24009d.

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Ketosis is a significant metabolic disorder in cows that occurs as a result of a negative energy balance, when the concentration of ketone bodies in the blood, milk and urine increases. Cow ketosis is a metabolic disease characterized by a disturbance in carbohydrate and fat metabolism with increased production of ketone bodies in the body. Basic metabolic adaptations in cows in ketosis are: increased concentration of BHB, increased concentration of NEFA, lower concentration of glucose, increased value of liver enzymes and bilirubin, disorder of macro and micro elements, increased values of in
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Reports on the topic "Liver marker enzymes"

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Kanner, Joseph, Dennis Miller, Ido Bartov, John Kinsella, and Stella Harel. The Effect of Dietary Iron Level on Lipid Peroxidation of Muscle Food. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604282.bard.

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Biological oxidations are almost exclusively metal ion-promoted reactions and in ths respect iron, being the most abundant, is the commonly involved. The effect of dietary iron levels on pork, turkey and chick muscle lipid peroxidation and various other related compounds were evaluated. Crossbred feeder pigs were fed to market weight on corn-soy rations containing either 62, 131 or 209 ppm iron. After slaughter, the muscles were dissected, cooked and stored at 4°C. Heavily fortifying swine rations with iron (&gt;200 ppm) increase nn-heme iron (NHI), thiobarbituric acid reactive substances (TBA
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