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Journal articles on the topic "LLHT"
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Macias-Escobar, Teodoro, Laura Cruz-Reyes, Bernabé Dorronsoro, Héctor Fraire-Huacuja, Nelson Rangel-Valdez, and Claudia Gómez-Santillán. "APPLICATION OF POPULATION EVOLVABILITY IN A HYPER-HEURISTIC FOR DYNAMIC MULTI-OBJECTIVE OPTIMIZATION." Technological and Economic Development of Economy 25, no. 5 (July 12, 2019): 951–78. http://dx.doi.org/10.3846/tede.2019.10291.
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It is important to know the properties of an optimization problem and the difficulty an algorithm faces to solve it. Population evolvability obtains information related to both elements by analysing the probability of an algorithm to improve current solutions and the degree of those improvements. DPEM_HH is a dynamic multi-objective hyper-heuristic that uses low-level heuristic (LLH) selection methods that apply population evolvability. DPEM_HH uses dynamic multiobjective evolutionary algorithms (DMOEAs) as LLHs to solve dynamic multi-objective optimization problems (DMOPs). Population evolvability is incorporated in DPEM_HH by calculating it on each candidate DMOEA for a set of sampled generations after a change is detected, using those values to select which LLH will be applied. DPEM_HH is tested on multiple DMOPs with dynamic properties that provide several challenges. Experimental results show that DPEM_HH with a greedy LLH selection method that uses average population evolvability values can produce solutions closer to the Pareto optimal front with equal to or better diversity than previously proposed heuristics. This shows the effectiveness and feasibility of the application of population evolvability on hyperheuristics to solve dynamic optimization problems.
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Silva-Souza, Lucas Geazi da, Luana Domingos de Oliveira, Gabriel Pereira Nunes, Laila dos Santos Cividanes, Cristian Michael Dahan, Andressa Kleyslla Guedes Pereira, Dárcio Kitakawa, Viviana Moraes Neder, and Luis Felipe das Chagas e. Silva de Carvalho. "Effectiveness of the low-level laser therapy in the management of bisphosphonate-induced osteonecrosis of the jaws: A case report." Research, Society and Development 10, no. 6 (May 24, 2021): e17510615199. http://dx.doi.org/10.33448/rsd-v10i6.15199.
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The aim of this study was to report a clinical case of osteonecrosis caused by bisphosphonates and its treatment with the aid of laser therapy. Low-level laser therapy (LLLT) is a resource used that is characterized by photobiostimulation and photobiomodulation, promoting analgesia and anti-inflammatory effects and can also be a tool for treating osteonecrosis induced by bisphosphonates (BFs), when associated also to drug therapy. The present case is a 63-year-old patient, leukoderma, with thyroid disorder and osteoporosis, making continuous use of medicaments classified as BF’s. He had a dental fracture and sensitivity to cold and treatment started with prophylaxis. After radiography of the dental elements, restorations were performed and tooth extraction (element 46). In the postoperative period, the patient reports pain and a bone exposure were observed clinically in the region of the extracted area, with osteonecrosis being diagnosed. Drug therapy was promptly applied and the use of LLLT was chosen as an adjunctive and supportive therapy. It is plausible to infer the need for attention to patients undergoing drug treatment with bisphosphonates, fully evaluating the best treatment for the possible occurrence of osteonecrosis in view of LLT as an effective complementary therapeutic approach.
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de Alencar F. Santos, Joelita, Renata Nicolau, Luciana Sant’Anna, Josne Paterno, Priscila Cristovam, Jose Gomes, José Santos, and Emilia Arisawa. "Diabetic Foot Wounds Treated With Human Amniotic Membrane and Low-level Laser Therapy: A Pilot Clinical Study." Wound Management & Prevention 67, no. 8 (August 10, 2021): 16–23. http://dx.doi.org/10.25270/wmp.2021.8.1623.
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BACKGROUND: Low-level laser therapy (LLLT) and human amniotic membrane (HAM) application have been shown to be viable options for use in wound healing. PURPOSE: This study sought to compare LLLT and HAM to a control treatment (hydrogel, saline, and gauze) in persons with diabetes mellitus (DM) and foot ulcers. METHODS: Using a prospective pilot clinical study design, patients receiving care at a health center that specializes in the treatment of diabetic foot wounds between November 2016 and August 2017 were recruited. Eligible patients had to be 30 to 59 years of age; diagnosed with type 2 DM (postprandial capillary glucose levels between 140 and 350 mg/dL); and have uninfected, granulating stage 2 or 3 foot ulcers measuring less than 7 cm by 3 cm. Immunosuppressed and malnourished patients or those with neoplasms or in critical condition were not eligible to participate. Patients received the control treatment (2 mg hydrogel, saline, and gauze), HAM (patches of thawed HAM, applied with overlapping edges), or LLLT (phototherapy session, 2 mg hydrogel, saline, and gauze) for 28 days. Variables, wound area measurements, Pressure Ulcer Scale for Healing (PUSH) scores, and Visual Analog Scale (VAS) scores were used to assess wound improvement progress and pain on days 7, 14, 21, and 28. Descriptive statistics were used to analyze the participant anthropometric and clinical profiles. The Kolmogorov-Smirnov test was used to analyze the sample distribution. The Kruskal-Wallis test with Dunn’s post-test was used to evaluate differences in PUSH and VAS scores and wound size for intergroup analysis, and the Mann-Whitney U test was used for the same outcomes in intragroup analysis. The level of significance was 5% (P < .05). RESULTS: Twenty-seven (27) patients participated (mean age, 51.4 years; mean body mass index, 26.5 kg/m2), with 9 patients in each treatment group. No statistically significant differences were noted in clinical or anthropometric variables among the groups, but mean baseline wound areas were different (2.6 cm² for the control, 1.9 cm² for the LLLT, and 5.5 cm² for the HAM groups). Intragroup comparisons showed a significant reduction in PUSH score in the LLT group between days 0 and 21 (8.2 vs 4.9; P < .01) and days 21 to 28 (4.9 vs 3.2; P < .001). In all treatment groups the percent reduction was significantly different between days 7 and 28. No outcomes were significantly different between groups. CONCLUSION: Diabetic foot ulcer wound area as well as PUSH and VAS scores showed more improvement for patients with DM receiving LLLT or HAM than for the control group, but the differences were not significant. Larger studies are needed to compare these treatment modalities.
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Lanferdini, Fábio J., Rodrigo R. Bini, Bruno M. Baroni, Kelli D. Klein, Felipe P. Carpes, and Marco A. Vaz. "Improvement of Performance and Reduction of Fatigue With Low-Level Laser Therapy in Competitive Cyclists." International Journal of Sports Physiology and Performance 13, no. 1 (January 1, 2018): 14–22. http://dx.doi.org/10.1123/ijspp.2016-0187.
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Evidence indicates that low-level laser therapy (LLLT) minimizes fatigue effects on muscle performance. However, the ideal LLLT dosage to improve athletes’performance during sports activities such as cycling is still unclear. Therefore, the goal of this study was to investigate the effects of different LLLT dosages on cyclists’performance in time-to-exhaustion tests. In addition, the effects of LLLT on the frequency content of the EMG signals to assess fatigue mechanisms were examined. Twenty male competitive cyclists participated in a crossover, randomized, double-blind, placebo-controlled trial. They performed an incremental cycling test to exhaustion (on day 1) followed by 4 time-to-exhaustion tests (on days 2–5) at their individual maximal power output. Before each time-to-exhaustion test, different dosages of LLLT (135, 270, and 405 J/thigh, respectively) or placebo were applied at the quadriceps muscle bilaterally. Power output and muscle activation from both lower limbs were recorded throughout the tests. Increased performance in time-to-exhaustion tests was observed with the LLLT-135 J (∼22 s; P < .01), LLLT-270 J (∼13 s; P = .03), and LLLT-405 J (∼13 s; P = .02) compared to placebo (149 ± 23 s). Although LLLT-270 J and LLLT-405 J did not show significant differences in muscle activation compared with placebo, LLLT-135 J led to an increased high-frequency content compared with placebo in both limbs at the end of the exhaustion test (P ≤ .03). In conclusion, LLLT increased time to exhaustion in competitive cyclists, suggesting this intervention as a possible nonpharmacological ergogenic agent in cycling. Among the different dosages, LLLT-135 J seems to promote the best effects.
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Barger, Brenna K., Adam M. Bisges, Derek B. Fox, and Bryan Torres. "Low-Level Laser Therapy for Osteoarthritis Treatment in Dogs at Missouri Veterinary Practice." Journal of the American Animal Hospital Association 56, no. 3 (May 1, 2020): 139–45. http://dx.doi.org/10.5326/jaaha-ms-6851.
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Abstract A qualitative survey was electronically distributed to practicing veterinarians in the state of Missouri to evaluate the frequency of use and economic impact of low-level laser therapy (LLLT) for the treatment of osteoarthritis (OA) in dogs in Missouri. The survey response rate was 10% (89/867). Approximately half (43%) of respondents had LLLT units, of which all used LLLT for OA treatment in dogs. In respondents without LLLT units, 20% referred patients for LLLT OA treatment. Training was most often obtained in-house by a representative of the LLLT unit manufacturer (76%). Treatment dose was largely unknown and chosen by predetermined settings on the LLLT unit (65%). In the majority of patients (84%), no treatment site preparation was performed. An average of four patients with OA were treated per wk with an average cost per treated joint of $28 (range: $15–45). This study provides insight into the current clinical use and estimated annual economic impact ($6.2 million per year) of treating a single OA joint in dogs with LLLT by Missouri veterinarians. The frequency with which LLLT is used in the treatment of OA combined with the variation in training and treatment protocols supports the need for further research regarding the application and efficacy of LLLT in dogs with OA.
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Alam, Mohammad Khursheed. "Laser-Assisted Orthodontic Tooth Movement in Saudi Population: A Prospective Clinical Intervention of Low-Level Laser Therapy in the 1st Week of Pain Perception in Four Treatment Modalities." Pain Research and Management 2019 (October 20, 2019): 1–11. http://dx.doi.org/10.1155/2019/6271835.
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Background. This first-in-human study in Saudi orthodontic patients has evaluated the role of low-level laser therapy (LLLT) in pain perception (PP). The outcome of single application of LLLT with 4 different treatment modalities (TM) on PP are evaluated following orthodontic bracket bonding on maxilla. Materials and Methods. A prospective clinical intervention with implementation of parallel technique in each group, 32 orthodontic patients with ectopic canine requiring fixed orthodontic appliance were enrolled and randomly allocated to the 4 groups: LLLT + self-ligating (SL) bracket, LLLT + conventional (Conv.) bracket, non-LLLT + SL bracket, and non-LLLT + Conv. bracket. Orthodontic bracket bonding from 1st molar to 1st molar and superelastic 0.012 inch NiTi were applied for the maxilla. For each patient, maxillary 1st molar to molar received a single application of LLLT using a 940 nm Ga-Al-As laser device on 5 different points labially/buccally and palatally. Main outcome measure was the degree of PP score during the 1st week of orthodontic tooth movement (OTM) after 4 hours, 24 hours, 3 days, and 7 days of both LLLT and non-LLLT treatment applications. A questionnaire with an 11-point numeric rating scale (NRS) was used for PP. Results. Mean ± SD of PP in the LLLT + SL group was 3.33 ± 1.4, 3.58 ± 1.06, 2.31 ± 0.67, and 1.89 ± 0.54 in 4 hours, 24 hours, 3 days, and 7 days, respectively. Compared to all 4 TM groups, LLLT groups showed better PP. More statistically significant differences were found in LLLT groups. No harms were encountered. Limitations. The intervention provider and the patient were not blinded to the intervention. Conclusion. The LLLT + SL group revealed significantly promising benefits on PP during OTM.
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Chen, Chia-Hsin, Chau-Zen Wang, Yan-Hsiung Wang, Wei-Ting Liao, Yi-Jen Chen, Chang-Hung Kuo, Hsuan-Fu Kuo, and Chih-Hsing Hung. "Effects of Low-Level Laser Therapy on M1-Related Cytokine Expression in Monocytes via Histone Modification." Mediators of Inflammation 2014 (2014): 1–13. http://dx.doi.org/10.1155/2014/625048.
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Low-level laser therapy (LLLT) has been used in the treatment of radiotherapy-induced oral mucositis and allergic rhinitis. However, the effects of LLLT on human monocyte polarization into M1 macrophages are unknown. To evaluate the effects of LLLT on M1-related cytokine and chemokine production and elucidate the mechanism, the human monocyte cell line THP-1 was treated with different doses of LLLT. The expression of M1-related cytokines and chemokines (CCL2, CXCL10, and TNF-α) was determined by ELISA and real-time PCR. LLLT-associated histone modifications were examined by chromatin immunoprecipitation (ChIP) assays. Mitochondrial involvement in the LLLT-induced M1-related cytokine expression was evaluated by quantitative real-time PCR. Flow cytometry was used to detect the cell surface markers for monocyte polarization. The results showed that LLLT (660 nm) significantly enhanced M1-related cytokine and chemokine expression in mRNA and protein levels. Mitochondrial copy number and mRNA levels of complex I-V protein were increased by LLLT (1 J/cm2). Activation of M1 polarization was concomitant with histone modification at TNF-αgene locus andIP-10gene promoter area. This study indicates that LLLT (660 nm) enhanced M1-related cytokine and chemokine expression via mitochondrial biogenesis and histone modification, which may be a potent immune-enhancing agent for the treatment of allergic diseases.
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Han, Der-Sheng, Cheng-Han Lee, Yih-Dar Shieh, and Chih-Cheng Chen. "Involvement of Substance P in the Analgesic Effect of Low-Level Laser Therapy in a Mouse Model of Chronic Widespread Muscle Pain." Pain Medicine 20, no. 10 (March 25, 2019): 1963–70. http://dx.doi.org/10.1093/pm/pnz056.
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Abstract Background Low-level laser therapy (LLLT) is widely used in pain control in the field of physical medicine and rehabilitation and is effective for fibromyalgia pain. However, its analgesic mechanism remains unknown. A possible mechanism for the effect of LLLT on fibromyalgia pain is via the antinociceptive signaling of substance P in muscle nociceptors, although the neuropeptide has been known as a neurotransmitter to facilitate pain signals in the spinal cord. Objective To establish an animal model of LLLT in chronic muscle pain and to determine the role of substance P in LLLT analgesia. Methods We employed the acid-induced chronic muscle pain model, a fibromyalgia model proposed and developed by Sluka et al., and determined the optimal LLLT dosage. Results LLLT with 685 nm at 8 J/cm2 was effective to reduce mechanical hyperalgesia in the chronic muscle pain model. The analgesic effect was abolished by pretreatment of NK1 receptor antagonist RP-67580. Likewise, LLLT showed no analgesic effect on Tac1-/- mice, in which the gene encoding substance P was deleted. Besides, pretreatment with the TRPV1 receptor antagonist capsazepine, but not the ASIC3 antagonist APETx2, blocked the LLLT analgesic effect. Conclusions LLLT analgesia is mediated by the antinociceptive signaling of intramuscular substance P and is associated with TRPV1 activation in a mouse model of fibromyalgia or chronic muscle pain. The study results could provide new insight regarding the effect of LLLT in other types of chronic pain.
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Choung, Lee, Ham, Lee, Kim, Pang, Jahng, and Lee. "Effectiveness of Low-Level Laser Therapy with a 915 Nm Wavelength Diode Laser on the Healing of Intraoral Mucosal Wound: An Animal Study and a Double-Blind Randomized Clinical Trial." Medicina 55, no. 8 (July 24, 2019): 405. http://dx.doi.org/10.3390/medicina55080405.
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Background and objectives: Diode laser has been the most popular low-level laser therapy (LLLT) technique in dentistry due to its good tissue penetration, lower financial costs, small size for portable application, and convenience to use. A series of recent studies with 940 nm or 980 nm lasers demonstrated that LLLT showed positive effects after third molar extraction or periodontal flap surgery. However, the effects of LLLT on intraoral mucosal wound healing after surgical incision have not yet been determined in human clinical study. Materials and Methods: The present study was performed to determine the efficacy and safety of 915 nm wavelength low-level laser therapy (LLLT) in mucosal wound healing. A total of 108 Sprague–Dawley rats were used. They were divided into three groups: Abrasive wound group, immediate LLLT once group, and daily LLLT group. As a clinical study, a total of 16 patients with split-mouth design subjected to bilateral mandibular third molar extraction were allocated into the LLLT group and placebo group. The process of LLLT was performed on postoperative days 0, 1, and 7, and parameters related to wound healing were analyzed on days 1, 7, and 14. Results: Repeated laser irradiation promoted mucosal wound healing of the rats. In the clinical study, although there were no significant statistical differences between the LLLT and placebo groups in all inflammatory parameters, the early stage mucosal healing tendency of wound dehiscence was higher in the LLLT group than in the placebo group clinically on postoperative day 1. Conclusions: The present results showed that 915 nm LLLT could be applied safely as an auxiliary therapy for mucosal wound healing.
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Xiong, Fen, Tian Mao, Hongfei Liao, Xiaoqin Hu, Lei Shang, Li Yu, Nana Lin, et al. "Orthokeratology and Low-Intensity Laser Therapy for Slowing the Progression of Myopia in Children." BioMed Research International 2021 (January 27, 2021): 1–10. http://dx.doi.org/10.1155/2021/8915867.
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Orthokeratology (OK) is widely used to slow the progression of myopia. Low-level laser therapy (LLLT) provides sufficient low energy to change the cellular function. This research is aimed at verifying the hypothesis that LLLT treatment could control myopia progression and comparing the abilities of OK lenses and LLLT to control the refractive error of myopia. Eighty-one children (81 eyes) who wore OK lenses, 74 children (74 eyes) who underwent LLLT treatment, and 74 children (74 eyes) who wore single-vision distance spectacles for 6 months were included. Changes in axial length (AL) were 0.23 ± 0.06 mm for children wearing spectacles, 0.06 ± 0.15 mm for children wearing OK lens, and − 0.06 ± 0.15 mm for children treated with LLLT for 6 months. Changes in subfoveal choroidal thickness (SFChT) observed at the 6-month examination were − 16.84 ± 7.85 μ m , 14.98 ± 22.50 μ m , and 35.30 ± 31.75 μ m for the control group, OK group, and LLLT group, respectively. Increases in AL at 1 month and 6 months were significantly associated with age at LLLT treatment. Changes in AL were significantly correlated with the baseline spherical equivalent refraction (SER) and baseline AL in the OK and LLLT groups. Increases in SFChT at 1 month and 6 months were positively associated with age at enrolment for children wearing OK lens. At 6 months, axial elongation had decelerated in OK lens-wearers and LLLT-treated children. Slightly better myopia control was observed with LLLT treatment than with overnight OK lens-wearing. Evaluations of age, SER, and AL can enhance screening for high-risk myopia, improve the myopia prognosis, and help determine suitable control methods yielding the most benefits.
Dissertations / Theses on the topic "LLHT"
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Fallon, Brendan. "Cobalt-catalyzed bond activation : C-H functionalization, hydrosilylation and coupling reactions." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066411/document.
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Dans cette thèse, nous nous concentrerons principalement sur l’utilisation de complexes basse-valence de cobalt bien définis de la famille des RCo(PMe3)4 pour l’activation de divers types de liaisons (C–H, Si–H, C–X). Notre but était de développer un système compétitif par rapport au système bimétallique de Yoshikai, mais aussi par rapport aux systèmes onéreux à base de rhodium. Nous avons démontré avec succès que les complexes isolés Co(PMe3)4 et HCo(PMe3)4 étaient des catalyseurs efficaces pour l’hydroarylation de différents alcynes et alcènes via une activation de liaisons C–H. De plus, nous avons fait une étude mécanistique en couplant des marquages au deutérium et des études de chimie théorique. Nous avons déterminé que la fonctionnalisation de liaisons C–H se faisait selon un mécanisme concerté appelé ‘’Ligand-to-Ligand Hydrogen Transfer’’ (LLHT). A partir de ces études, nous avons pu aussi développer une hydrosilylation hautement régio- et stéréosélective d’alcynes permettant d’utiliser un grand nombre de silanes différents. Nous avons pu au cours de cette étude isoler un nouveau complexe de cobalt(III) bis-hydrure jouant un rôle important dans le mécanisme. Enfin, nous décrivons aussi que ces mêmes complexes de cobalt RCo(PMe3)4 sont capables de catalyser l’homocouplage de bromure et chlorure de benzyle en présence de dimethylzinc. Une étude mécanistique préliminaire suggère que la réaction procède par deux transferts mono-électroniques et que le diméthylzinc permet de régénérer le catalyseurThis thesis has focused on the use of well-defined low-valent cobalt complexes of the family RCo(PMe3)4 for a variety of bond activation (C–H, Si–H, C–X). We aimed to develop a catalytic system that could compete with the previously reported bimetallic systems of Yoshikai and expensive rhodium catalysis. To this end, we successful demonstrated that Co(PMe3)4 and HCo(PMe3)4 are efficient catalysts for the hydroarylation of a broad variety of alkynes and alkenes. In addition, we carried out extensive mechanistic investigations using deuterium labelling experiments and theoretical studies namely DFT. The main finding of these studies was that the C–H bond activation proceeded via a ligand-to-ligand hydrogen transfer mechanism. Following on from this study we then showed that it was possible to carry out the regio- and stereoselective hydrosilylation of internal alkynes with a broad variety of hydrosilanes. During this study we successfully isolated an interesting cobalt(III) intermediate which we believe plays a crucial role in the reaction mechanism. Finally, we report on the ability of these catalysts to efficiently catalyze the homocoupling of benzyl halides in the presence of dimethylzinc. Initial mechanistic investigations suggest that the reaction takes via two single electron transfers and that dimethylzinc act to regenerate the catalyst
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Wu, Yang. "Accélération de la simulation logique : architecture et algorithmes de LL3T." Phd thesis, Grenoble INPG, 1990. http://tel.archives-ouvertes.fr/tel-00338790.
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Cette thèse présente la conception d'un accélérateur matériel dédié à la simulation de circuits intégrés. Sur cet accélérateur sont développés un ensemble de logiciels constituant un environnement intégré de simulation. Nous y discutons tout d'abord des concepts de base de la modélisation des circuits intégrés, de la simulation logico-fonctionnelle, de la simulation de pannes, des langages de description du matériel, ainsi que des techniques d'accélération de la simulation de circuits intégrés. Nous présentons ensuite la structure générale de l'accélérateur. Il est basé sur une architecture parallèle : un réseau en anneau sur lequel sont disposées des unités de simulation, où chaque unité de simulation est composée de trois microprocesseurs exécutant trois tâches respectivement. l'ensemble des logiciels implémentés sur cet accélérateur est présenté. Le simulateur réalise ainsi la simulation multi-niveaux (porte logique, fonctionnel et interrupteur) et la simulation de pannes. Des outils de compilation permettent l'utilisation des langages de description du matériel pour modéliser les circuits intégrés de manière structurelle et fonctionnelle. Enfin, différentes stratégies de parallélisation de la simulation ainsi que plusieurs algorithmes de simulation adaptés aux différents niveaux d'abstraction sont étudiés
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Wu, Yang Mazaré Guy Verjus Jean-Pierre Borrione Dominique. "Accélération de la simulation logique architecture et algorithmes de LL3T /." S.l. : Université Grenoble 1, 2008. http://tel.archives-ouvertes.fr/tel-00338790.
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Oliveira, Flávia Amadeu de. "Efeito dos laseres de baixa intensidade na proliferação e diferenciação de osteoblastos humanos." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/25/25149/tde-23042014-100944/.
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Dentre os vários compostos utilizados na pesquisa e na terapia de doenças osteo-degenerativas, a fototerapia com laseres de baixa potência (LLLT) e os diodos emissores de luz (LEDs) vem sendo investigada com o intuito de avaliar seus efeitos no metabolismo ósseo. Estes, que possuem comprimentos de ondas específicos, atuam na biomodulação das células, funcionando como um agente terapêutico, reequilibrando e normalizando a sua atividade. No entanto, pouco se sabe sobre o efeito dos diferentes espectros na proliferação e diferenciação de osteoblastos humanos, bem como seus efeitos no metabolismo celular como a síntese e a ativação de proteínas sinalizadoras envolvidas nesses processos. Diante disso, o objetivo deste trabalho foi avaliar, comparativamente, a influência da fototerapia com LLLT e LED na proliferação e diferenciação de osteoblastos humanos. Além disso, investigamos o envolvimento da ativação da via de sinalização ERK1,2 nestas respostas, utilizando o seu inibidor específico e/ou avaliando a sua ativação durante a proliferação e após fototerapia. Para esse estudo, osteoblastos humanos (HOAL) foram cultivados em meio de cultura DMEM suplementado com 10% de soro fetal bovino (SFB) e incubados em estufa de CO2. As células foram irradiadas pontualmente com os laseres vermelho (660nm), infravermelho (780nm) e LED (637nm), nas doses de 10, 20 e 50 J/cm2 na potência de 40mW, após adesão celular. Após 24, 48, e 72 horas foram realizados os ensaios de redução do MTT (brometo de 3-(4,5-dimetiltiazol-2-yl)-2,5- difeniltetrazólio) e cristal violeta (CV) para avaliar a viabilidade das células e após 72 horas foi realizada a análise da proliferação por citometria de fluxo nos quais os resultados sugerem aumento de células viáveis ou proliferação quando estimuladas pelos diferentes espectros. Após a verificação do efeito positivo dos laseres e LED na viabilidade e/ou proliferação, foi realizada a análise da ativação da proteína intracelular ERK por western blotting usando anticorpo específico após 10 minutos da irradiação pontual. Mostramos que a irradiação das células HOAL com LLLT, na dose de 10 J/cm2, aumentou significativamente a fosforilação da ERK1/2 em relação ao controle. Para os ensaios de diferenciação, as células receberam pontualmente o estimulo a cada 6 dias e após os períodos de 07, 14, 21 e 28 dias foram realizados os ensaios da atividade de fosfatase alcalina (ALP), expressão gênica do colágeno I (COL1A1) e SPARC (osteonectina) por RT-PCR em tempo real e ensaio de mineralização com vermelho de alizarina. De um modo geral, não foram observados diferenças na atividade da ALP entre os grupos tratados em relação ao controle. A expressão gênica do COL1A1 e SPARC foi aumentada, no qual o LED em ambas doses apresentou maior eficácia em aumentar a expressão desses genes. No que se refere à mineralização, foram observadas pequenas diferenças quanto a deposição de cálcio. Dessa forma, a LLLT e LED, nesse regime de aplicação modulou positivamente o metabolismo dos osteoblastos humanos em relação à viabilidade, porém, no processo de mineralização foram observadas poucas diferenças.Among the various compounds used in research and bone degenerative diseases therapy, phototherapy with low level laser (LLLT) and light emitting diodes (LEDs) has been investigated in order to evaluate its effects on bone metabolism. Those, who have specific wavelengths, act in biomodulation cells functioning as a therapeutic agent, rebalancing and normalizing their activity. However, little is known about the effect of the different spectra in the proliferation and differentiation of human osteoblasts and their effects on cellular metabolism as well as the synthesis and activation of signaling proteins involved in these processes. Therefore, the aim of this study was to compare the influence of LLLT and LED phototherapy in the proliferation and differentiation of human osteoblasts. In addition, we investigated the involvement of activation of ERK1,2 signaling pathway these responses using its specific inhibitor and/or evaluating their activation during the proliferation and after phototherapy. For this study, human osteoblasts (HOAL) were cultured in DMEM culture medium supplemented with 10 % fetal bovine serum (FBS) and incubated in CO2 incubator . Cells were irradiated with punctual red lasers (660nm), infrared (780nm) and LED (637nm) at doses of 10, 20 and 50 J/cm2 in power 40mW, after cell adhesion. After 24, 48, and 72 hours, MTT assay (- (4,5- dimethylthiazol-2- yl) -2,5 - diphenyltetrazolium bromide 3 ) and violet crystal (CV) were performed to assess the viability of cells and after 72 hours, was performed of proliferation analysis by flow cytometry. The results suggest an increase in viable and proliferation of cells when stimulated by different spectra. After checking the positive effect of lasers and LED viability and/or proliferation, analysis of ERK activation of intracellular protein by western blotting using a specific antibody was performed 10 minutes after the spot irradiation. We show that irradiation of HOAL cells with LLLT at a dose of 10 J/cm2, significantly increased the phosphorylation of ERK1/2 compared to control. For differentiation assays, cells promptly received stimulation every 6 days and after periods of 07, 14, 21 and 28 days testing the activity of alkaline phosphatase (ALP), gene expression of type I collagen (COL1A1) and SPARC (osteonectin) were performed by Real Time RT-PCR and mineralization experiment with alizarine red. In general, no differences in the activity of ALP between the treated groups compared to the control were observed. The gene expression was increased, and SPARC COL1A1, where in the LED in both doses showed greater effectiveness in increasing the expression of these genes. With respect to mineralization, small differences in the deposition of calcium were observed. Thus, LLLT and LED, this enforcement regime, positively modulated the metabolism of human osteoblasts during the cell viability, but in the process of mineralization few differences were observed.
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Mussttaf, Ruwaidah Abdulameer. "Laser light interaction and their influence on DNA and cell under in vitro conditions." Thesis, University of Plymouth, 2018. http://hdl.handle.net/10026.1/11888.
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Laser photobiomodulation (PBM) or low-level laser therapy (LLLT) is a form of phototherapy recognized worldwide for its expansive use in medicine. PBM/LLLT has the ability to enhance enzymatic activity and mitochondrial transmembrane potential that increase the availability of energy and the signal transduction, which promotes cell proliferation. This study primarily investigates the appropriateness of a range of treatment parameters, including light wavelength, irradiance (doses) and exposure time of PBM/LLLT in proliferation of cultured human monocytic leukaemia cell line THP-1(Tamm-Horsfall Protein 1), as well as DNA under in vitro conditions. A secondary objective was to exploit the beneficial effect of PBM/LLLT to reduce the harmful impacts caused by exposure to ultraviolet (UV) radiation. Cells were irradiated with near infrared (NIR) diode laser at 850 nm with doses ranging from 0 – 26.8 J/cm2. After irradiation, cells were incubated for 12 hr and 24 hr to allow time for proliferation. Comet assay was conducted to evaluate genotoxicity of the irradiated cells. Trypan blue exclusion test and MTT assay (3-4-5-dimethy-2.5 thiazol-2.5 diphenyl tetrazolium bromide) were used to estimate cytotoxicity, Exposure to NIR diode laser revealed the beneficial effect of PBM/LLLT at low doses (< 5 J/cm2), which increased the viability and proliferation of THP-1 cells, which conformed by increasing ATP synthesis and the activity of mitochondria. Comet assay showed no significant difference between irradiated and non-irradiated cells at low doses and showed no DNA damage. The photobiomodulation effect of low doses, in particular 0.6 J/cm2 and 1.2 J/cm2, managed to reduce the damage to THP-1 cells after exposure to UV radiation by decreasing cell apoptosis, accelerate DNA damage repair and increase cell survival. While, the exposure for high doses (> 5 J/cm2), showed different results involved decrease in the number of THP-1 cells and viability, in addition to a considerable increase in DNA damage, which emphasised by decrease in the level of ATP synthesis and reducing the mitochondrial activity. These findings demonstrated the photobiomodulation effect of NIR diode laser through modulating various pathways such as ATP synthesis and mitochondrial activity in monocyte cells and DNA.
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Campagnaro, Milene Borges. "Efeitos embriot?xicos e teratog?nicos da LLLT : estudo em zebrafish." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2016. http://tede2.pucrs.br/tede2/handle/tede/6798.
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The low-level laser therapy (LLLT) has been widely used in Dentistry, considering its local and systemic effects as well as its therapeutic and biomodulatory action on the tissues. Therefore, the aim of this study was to evaluate the embryotoxicity, teratogenesis and systemic alteration caused by LLLT, using a diode laser (GaAlAs) with infrared (?830nm, 90mW, CW) and red (?685nm, 30mW, CW) wavelengths, in the initial development of the Zebrafish embryos. For this, 1560 embryos, monitored from fecundation to 5 dpf, were used and the eclosion, embryotoxicity, and survival rates, were measured. The analysis of the heartbeat, exploratory and aversive behavior, calcein and alcian blue techniques were realized only in the end of the experiment, with 5 dpf. The animals were divided in three groups. One control group (Ctrl) with 140 animals without LLLT, and two experimental groups, with 710 animals each, irradiated with infrared laser (IR) or red laser (R). The experimental groups were subdivided in five subgroups according to the energy densities of energy received (0.5J, 1.0J, 2.0J, 4.0J, 8.0J) with 142 animals in each subgroups. The LLLT was performed in the first, second and fifth dpf, according to the stipulated parameters. The results obtained in the present study showed that in groups with LLLT, there was a delay in the eclosion, a higher mortality rate and the presence of teratogenic Changes in the animals, as well as behavioral alterations, when compared to control group. The heartbeat was higher in both IR and R groups, when compared to the control group, with the IR group sowing the highest values. The cartilage and bone formation didn?t show any visually alterations, keeping the normality standards.
A laserterapia de baixa intensidade (LLLT/Low-Level Laser Therapy) tem sido amplamente utilizada na Odontologia, tendo em vista seus efeitos locais e sist?micos, terap?uticos e biomodulat?rios sobre os tecidos. Assim, o objetivo deste estudo foi avaliar a embriotoxicidade, a teratog?nese e as altera??es sist?micas provocadas pela LLLT, utilizando um laser de diodo (GaAlAs) infravermelho (?830nm, 90mW, CW) e vermelho (?685nm, 30mW, CW), sobre o desenvolvimento inicial de embri?es de Zebrafish. Para isso, foram utilizados 1560 embri?es, acompanhados desde a fecunda??o at? o 5dpf. Foram realizadas ao longo dos cinco dias de acompanhamento, a avalia??o das taxas de eclos?o, embriotoxicidade e sobreviv?ncia. As an?lises como batimento card?aco, comportamento explorat?rio, comportamento aversivo, t?cnica da calce?na e t?cnica do alcian blue foram realizadas somente no final do experimento, no 5dpf. Os animais foram divididos em tr?s grupos. Um grupo com 140 animais e sem aplica??o de laser serviu como controle (Ctrl) e dois grupos experimentais, foram irradiados com laser Infra-vermelho (IR) ou com laser Vermelho(R), ambos com 710 animais. Os grupos IR e R foram subdivididos em cinco subgrupos conforme as densidades de energia recebidas: 0.5J, 1.0J, 2.0J, 4.0J, 8.0J, com142 animais em cada subgrupo. Foram realizadas tr?s sess?es de laserterapia, no 1?, 3? e 5?dpf, de acordo com os par?metros de cada dose utilizada. Os resultados obtidos na presente pesquisa demonstram que nos grupos em que o laser foi aplicado, houve um retardo na eclos?o, uma maior mortalidade e presen?a de altera??es teratog?nicas dos animais, bem como altera??es comportamentais, quando comparados com o grupo controle. Os valores para os batimentos card?acos foram maiores para os grupos R e IR, quando comparados com o grupo controle, sendo que o grupo IR apresentou os maiores valores. A forma??o cartilaginosa e ?ssea n?o apresentou altera??es qualitativas visualmente percept?veis, se mantendo no padr?o de normalidade.
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Molinari, Petr. "Návrh systému horizontálního pohonu unašeče skladovacího systému LLH." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2015. http://www.nusl.cz/ntk/nusl-232029.
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The aim of this diploma thesis is system design of the horizontal drive carrier storage system LLH. In the first part describes the problems of storage of bars, complemented by an overview of commercially used vertical storage systems. Next part is devoted to build computational algorithm for t he design of the carrier drive system. With this algorithm, the device is designed in the final part.
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Torri, Simone. "Influência da LLLT (GaAlAs) com diferentes energias na Movimentação ortodôntica em ratos." Pontifícia Universidade Católica do Rio Grande do Sul, 2013. http://hdl.handle.net/10923/5510.
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Previous issue date: 2013Introduction: Prolonged treatment times are one of the greatest challenges of orthodontic practice. Research has shown that laser therapy can be used as an adjunct to orthodontic movement, with effects on bone repair and analgesia. This study sought to assess the influence of low-level laser therapy (LLLT), using different energy settings, on orthodontic tooth movement in rats. Methods: Twenty-five male Wistar rats were randomly allocated across four different energy setting groups and one control group. A 10-g load was applied to the left maxillary first molar. During orthodontic movement, 830-nm laser radiation was administered to three spots at different energy settings depending on group allocation (12J, 15J, 18J, or 21J per site). Orthodontic movement was measured throughout the experiment and calcein dye was injected into the specimens for measurement of the area of neoformed bone. Results: There were no significant quantitative differences in orthodontic movement between the control and LLLT groups (P<0. 01). On histological examination, LLLT groups 12J, 15J, and 18J exhibited a significant increase in area of neoformed bone (P<0. 05).Conclusions: At the energy settings and protocols used in this study, LLLT does not appear to influence the rate of orthodontic movement, although different energy settings encourage bone neoformation.
Introdução: Um dos grandes desafios da ortodontia nos dias atuais é a diminuição do tempo de tratamento. Estudos tem demonstrado que o laser pode ser um auxiliar na movimentação ortodôntica, influenciando na reparação óssea e na analgesia. O objetivo desse trabalho foi analisar a influência da Low-Level Laser Therapy (LLLT) com diferentes energias na quantidade da movimentação ortodôntica em ratos.Métodos: Vinte e cinco ratos machos Wistar foram divididos aleatoriamente em cinco grupos de acordo com a energia de laser aplicada. Uma força de 10 gramas foi aplicada ao primeiro molar superior esquerdo. Nele foi aplicado laser, 830nm, com diferentes energias durante a movimentação ortodôntica (12J, 15J, 18J, 21J por ponto) em 3 pontos. A quantidade de movimentação dentária foi mensurada durante o experimento e calceína foi injetada nas amostras para marcar e possibilitar a mensuração da área do osso neoformado. Resultados: Com relação à quantidade de movimentação, não houve diferença estatisticamente significante entre o grupo controle e os grupos LLLT (P<0,01). Histologicamente, houve aumento significativo da área de osso neoformado nos grupos LLLT com energias de 12, 15 e 18J (P<0,05).Conclusões: Esses achados sugerem que a LLLT nas energias e protocolos aplicados nesse estudo não interferem na quantidade da movimentação dentária ortodôntica, apesar de estimular a neoformação óssea com a aplicação de determinadas energias.
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Mayer, Luciano. "Análise do efeito sistêmico da LLLT em região perimplantar : estudo em coelhos." Pontifícia Universidade Católica do Rio Grande do Sul, 2013. http://hdl.handle.net/10923/1079.
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Este estudo é parte de um projeto que teve por objetivo avaliar o efeito da terapia com laser de baixa intensidade pós-implante dentário osseointegrável no funcionamento da glândula tireoide e, consequentemente, na regulação do cálcio, através da mensuração dos níveis hormonais de Triiodotironina (T3), Tiroxina (T4) e dos níveis de Cálcio e Albumina no soro sanguíneo de coelhos. Foi avaliado o efeito de 3 doses terapêuticas distintas de LLLT utilizadas para aceleração do processo de osseointegração de implantes dentários. Para tanto, foram utilizados 40 coelhos da ordem Lagomorpha, raça Nova Zelândia, machos, pesando entre 3 e 4 kg, clinicamente sadios, distribuídos aleatoriamente em cinco grupos, com oito animais cada, sendo dois grupos designados como controle: o grupo controle CI (animais não irradiados e não operados) e o grupo controle CII (animais não irradiados); e três grupos designados como experimentais: EI, EII e EIII – animais irradiados com três doses distintas de laser – grupo experimental EI (dose total - 70J/cm²), grupo experimental EII (dose total - 35J/cm²) e grupo experimental EIII (dose total - 140J/cm²). Para padronizar os experimentos, todos os animais dos grupos CII, EI, EII e EIII foram submetidos ao procedimento cirúrgico de exodontia do incisivo inferior esquerdo e colocação imediata de um implante osseointegrável com superfície nanotexturizada (Nanotite® - Biomet 3iTM) no respectivo alvéolo, criando uma condição clínica inicial de igualdade entre os quatro grupos operados. Os animais do grupo controle CI participaram da mesma rotina dos demais; no entanto, não foram submetidos a nenhum dos procedimentos clínicos/cirúrgicos, servindo como controle absoluto nos testes imunológicos para contagem de T3, T4, Cálcio e Albumina. Os animais dos grupos experimentais foram irradiados com o laser de diodo infravermelho com meio ativo GaAlAs (Arseneto de Gálio e Alumínio), com comprimento de onda de 830nm, de forma pontual, com potência de 50mW, no modo de emissão contínua, a cada 48 horas, num total de sete sessões de aplicação, durante o período de 13 dias. O protocolo de irradiação foi iniciado imediatamente após o procedimento cirúrgico. As coletas de sangue para dosagens laboratoriais de T3, T4, Cálcio e Albumina foram realizadas por meio de punção venosa da veia jugular nos cinco grupos em quatro momentos distintos: 72 horas antes do procedimento cirúrgico, imediatamente após a primeira aplicação de laser, 72 horas após a primeira aplicação de laser e 72 horas após a última aplicação de laser. Os resultados obtidos demonstraram diferenças estatisticamente significativas para os valores de T3 e Cálcio entre os grupos estudados e para os valores de T3, T4, Cálcio e Albumina nos diferentes tempos de coleta ao longo do experimento. Conclui-se que a LLLT, no protocolo de irradiação utilizado neste estudo, apesar de ter alterado significativamente os níveis hormonais de T3 e T4 e os níveis de Cálcio e Albumina circulantes no soro de coelhos, não comprometeu definitivamente o funcionamento da glândula tireoide dos mesmos, pois na etapa final do controle hormonal percebe-se o restabelecimento da função glandular.
This study is part of a larger project that sought to assess the effect of lowlevel laser therapy (LLLT) after placement of an osseointegrated dental implant on thyroid gland function – and, consequently, calcium regulation – and its potential interference with the osseointegration process. Toward this end, circulating serum levels of triiodothyronine (T3), thyroxine (T4), calcium, and albumin were measured in rabbits. The effects of three therapeutic doses of LLLT, used to accelerate the dental implant osseointegration process, were assessed. Forty healthy male New Zealand rabbits (order Lagomorpha), weight 3–4 kg, were allocated randomly across five groups of eight each: two control groups, CI (no LLLT, no surgery) and CII (no LLLT), and three experimental groups, EI, EII, EIII, exposed to three different doses of laser radiation (EI, total dose 70 J/cm²; EII, total dose 35 J/cm²; and EIII, total dose 140 J/cm²). For standardization purposes, all animals in groups CII, EI, EII, and EIII underwent surgical extraction of the mandibular left incisor and immediate placement of a nanoparticle-coated osseointegrated implant (NanoTite® – Biomet 3iTM) into the prepared socket, creating a condition of equality between groups at baseline. Animals in group CI were exposed to the same handling conditions, but did not undergo any clinical or surgical procedures, thus serving as an absolute control for T3, T4, calcium, and albumin measurements. Animals in the experimental groups received spot irradiation with a GaAlAs (gallium aluminium arsenide) infrared diode laser, wavelength 830 nm, power 50 mW, in continuous emission mode, over two points, every 48 hours over 13 days, for a total of seven sessions; the irradiation protocol was started immediately after the surgical procedure. Blood was collected for measurement of T3, T4, calcium, and albumin levels, by puncture of the external jugular vein, at four points in time: 72 hours before surgery, immediately after the first LLLT session, 72 hours after the first LLLT session and 72 hours after the last LLLT session. The results showed significant differences in T3 and calcium levels between study groups, as well as significant within-group differences in T3, T4, calcium, and albumin levels over time. We conclude that, despite a significant effect on circulating serum levels of T3, T4, calcium and albumin, the LLLT protocol used in this study did not lead to impairment of thyroid function in a rabbit model, because in the final stage of the hormonal control it is noticed the reestablishment of glandular function.
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Andreasson, Emma, and Sanna Lindgren. "Fysioterapeuters subjektiva upplevelse och erfarenhet av LLLT som behandlingsmetod vid muskelskada : En tvärsnittsstudie." Thesis, Luleå tekniska universitet, Institutionen för hälsa, lärande och teknik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-84935.
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Introduktion: Det Muskuloskeletala systemet består av skelettmuskulatur, nervsystem och skelett. Systemet bidrar till att kroppen kan röra sig. Muskelskador kan uppkomma genom direktvåld mot muskeln eller kraftig uttöjning och skadan bidrar till smärta och svullnad. Vanliga behandlingsmetoder på muskelskada är NSAID och andra fysioterapeutiska interventioner. Low- level laser therapy (LLLT) har senaste tiden fått ökad acceptans och blivit mer intressant. LLLT används med varierad dosering för att stimulera cellfunktion, minska smärta och påskynda läkningsprocessen. Tidigare studier visar varierat resultat av LLLT på muskelskador, därför vill vi undersöka den beprövade erfarenheten, eftersom det inte undersöks vetenskapligt utan finns bland klinikerna. När LLLT utförs med den mest gynnsamma dosen har behandlingen en pålitlig och biologisk verkan på muskelvävnad. Vi vill se om fysioterapeuters upplevelse av LLLT speglar tidigare forskning. Syftet: med studien är att undersöka fysioterapeuters subjektiva upplevelse och erfarenhet av low-level laser therapy (LLLT) som behandlingsmetod vid muskelskada. Metod: Studien är en kvantitativ tvärsnittsstudie med en online enkät. 30 Leg. Fysioterapeuter med mer än 1 års erfarenhet av LLLT deltog. Fysioterapeuterna rekryterades via 2 portaler och mejlutskick. Resultat: Majoriteten av fysioterapeuterna anser att LLLT är en adekvat behandlingsmetod på muskelskada och patienter upplevs nöjda. Fysioterapeuterna hade varierade upplevelser med en antydan till samband mellan upplevd effekt och dosering (J) på muskelskada som kunde noteras. Konklusion: Enligt de deltagande fysioterapeuterna har LLLT effekt på muskelskada och anses vara en adekvat behandlingsmetod. Det finns en antydan till ett visst samband mellan hänsynstagandet till dos och effekten.
Books on the topic "LLHT"
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Cuxart, Raimon. Contes per llegir sobre el llit ; Contes per llegir sota el llit. Barcelona: Llibres de l'Índex, 2002.
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Parpal, Antoni Seguí. Racionament alimentari de vaques de llet. [Barcelona]: Caixa de Catalunya, Servei Agrari, 1988.
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al-Raḥmān, Ilyās Fatḥ. Laysat dumūʻ al-llāt ḥuznan ʻalá al-ʻuzzá. al-Kharṭūm: Dār Madārik lil-Ṭibāʻah wa-al-Nashr wa-al-Tawzīʻ, 2009.
Find full textBook chapters on the topic "LLHT"
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Inui, Shigeki. "LLLT: Does It Work?" In Practical Aspects of Hair Transplantation in Asians, 653–57. Tokyo: Springer Japan, 2017. http://dx.doi.org/10.1007/978-4-431-56547-5_69.
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Mazo, Vsevolod. "Transrectal LLLT in Prostatic Problems’ Management." In Laser in der Medizin / Laser in Medicine, 37–39. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-93548-0_10.
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Minotto, R., and L. Damiani. "Low-Level Light Therapy (LLLT) in Alopecia." In Minimally Invasive Aesthetic Procedures, 781–83. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-78265-2_110.
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Rhee, Chung-Ku. "Low Level Laser (Light) Therapy (LLLT) in Otolaryngology." In Biomedical Optics in Otorhinolaryngology, 235–51. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-1758-7_16.
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Chittoria, Ravi Kumar, and Sudhanva H. Kumar. "Low-Level Laser Therapy (LLLT) in Wound Healing." In Chronic Wounds, Wound Dressings and Wound Healing, 21–26. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/15695_2017_89.
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Lee, James. "Chapter 14. Ideas for the practice of instructed SLA and their rationale." In Language Learning & Language Teaching, 311–28. Amsterdam: John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/lllt.38.19lee.
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Li, Mimi. "Chapter 7. Languaging in wiki-based collaborative writing:." In Language Learning & Language Teaching, 150–69. Amsterdam: John Benjamins Publishing Company, 2020. http://dx.doi.org/10.1075/lllt.55.07li.
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Chalhoub-Deville, Micheline. "Drawing the line." In Language Learning & Language Teaching, 1–5. Amsterdam: John Benjamins Publishing Company, 2006. http://dx.doi.org/10.1075/lllt.12.01cha.
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Dinsmore, Thomas H. "2. Principles, parameters, and SLA." In Synthesizing Research on Language Learning and Teaching, 53–90. Amsterdam: John Benjamins Publishing Company, 2006. http://dx.doi.org/10.1075/lllt.13.07din.
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Sauro, Shannon J. "7. The cyber language exchange." In Language Learning & Language Teaching, 129–46. Amsterdam: John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/lllt.34.11ch7.
Full textConference papers on the topic "LLHT"
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Shen, Bor-Yeh, Jiunn-Yeu Chen, Wei-Chung Hsu, and Wuu Yang. "LLBT." In the 2012 international conference. New York, New York, USA: ACM Press, 2012. http://dx.doi.org/10.1145/2380403.2380419.
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Marten, David, Matthew Lennie, Georgios Pechlivanoglou, Christian Navid Nayeri, and Christian Oliver Paschereit. "Implementation, Optimization and Validation of a Nonlinear Lifting Line Free Vortex Wake Module Within the Wind Turbine Simulation Code QBlade." In ASME Turbo Expo 2015: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/gt2015-43265.
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The development of the next generation of large multi-megawatt wind turbines presents exceptional challenges to the applied aerodynamic design tools. Because their operation is often outside the validated range of current state of the art momentum balance models, there is a demand for more sophisticated, but still computationally efficient simulation methods. In contrast to the Blade Element Momentum Method (BEM) the Lifting Line Theory (LLT) models the wake explicitly by a shedding of vortex rings. The wake model of freely convecting vortex rings induces a time-accurate velocity field, as opposed to the annular averaged induction that is computed from the momentum balance, with computational costs being magnitudes smaller than those of a full CFD simulation. The open source code QBlade, developed at the Berlin Institute of Technology, was recently extended with a Lifting Line - Free Vortex Wake algorithm. The main motivation for the implementation of a LLT algorithm into QBlade is to replace the unsteady BEM code AeroDyn in the coupling to FAST to achieve a more accurate representation of the unsteady aerodynamics and to gain more information on the evolving rotor wake and flow-field structure. Therefore, optimization for computational efficiency was a priority during the integration and the provisions that were taken will be presented in short. The implemented LLT algorithm is thoroughly validated against other benchmark BEM, LLT and panel method codes and experimental data from the MEXICO and NREL Phase VI tests campaigns. By integration of a validated LLT code within QBlade and its database, the setup and simulation of LLT simulations is greatly facilitated. Simulations can be run from already existing rotor models without any additional input. Example use cases envisaged for the LLT code include; providing an estimate of the error margin of lower fidelity codes i.e. unsteady BEM, or providing a baseline solution to check the soundness of higher fidelity CFD simulations or experimental results.
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Biswas, Abhijit, and Joseph M. Kovalik. "The Lunar Laser OCTL Terminal (LLOT)." In SPIE LASE, edited by Hamid Hemmati and Don M. Boroson. SPIE, 2013. http://dx.doi.org/10.1117/12.2006454.
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Magrini, Taciana D., Arnaldo R. Santos, Jr., and Herculano da Silva Martinho. "Standardization of experimental parameters for LLLT studies." In SPIE BiOS, edited by Michael R. Hamblin, Juanita Anders, and James D. Carroll. SPIE, 2012. http://dx.doi.org/10.1117/12.908363.
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Brugnera, Jr., Aldo, Fatima Zanin, Thereza C. Ladalardo, Antonio Pinheiro, and Jesus D. Pecora. "LLLT in treating dentinary hypersensitivity: new concepts." In Biomedical Optics 2006, edited by Michael R. Hamblin, Ronald W. Waynant, and Juanita Anders. SPIE, 2006. http://dx.doi.org/10.1117/12.668687.
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Sampath, V., R. Mohan, S. Wang, L. Gomez, O. Shoham, and J. Marrelli. "Intelligent Control of Compact Multiphase Separation System (CMSS©)—Part I: Modeling and Simulation." In ASME 2009 Fluids Engineering Division Summer Meeting. ASMEDC, 2009. http://dx.doi.org/10.1115/fedsm2009-78422.
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Performance of compact separators depends on implementation of stable and robust control strategies that are suited for specific applications. In this investigation, an intelligent control system has been developed for Compact Multiphase Separation System (CMSS©) which consists of integrated configurations of three compact separators, namely, Gas-Liquid Cylindrical Cyclone (GLCC©), Liquid-Liquid Cylindrical Cyclone (LLCC©) and Liquid-Liquid Hydrocyclone (LLHC). This is a two-part paper, the first part (current paper) deals with the Modeling and Simulation of the CMSS© and the second part deals with Experimental Investigation. The specific objective of this CMSS© configuration is to knock out free water from the upstream fluids. In mature oil fields, water handling poses a huge problem. Thus water knock out at the earliest stage helps in significant cost savings. A novel fuzzy logic control system has been designed and tested for change in set-point of differential pressure ratio in LLHC. Dynamic models have been developed for each of the above mentioned control systems for design of stable PID parameters. A dynamic simulation platform (DSP) has been developed based on these models in Matlab/Simulink™ for predicting the transient performance of the integrated system. Steady state mechanistic models of individual devices are integrated to the Matlab/Simulink™ platform using look up tables to predict the overall response of the CMSS© for different scenarios.
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Wolbarsht, Myron L. "Low-level laser bioeffects (LLLT) and safety considerations." In ILSC® ‘92: Proceedings of the International Laser Safety Conference. Laser Institute of America, 1992. http://dx.doi.org/10.2351/1.5056324.
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Roberts, W. Thomas, and Malcolm W. Wright. "The Lunar Laser OCTL Terminal (LLOT) optical systems." In SPIE LASE, edited by Hamid Hemmati and Don M. Boroson. SPIE, 2013. http://dx.doi.org/10.1117/12.2004415.
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Barolet, D. "The importance of pulsing illumination parameters in LLLT." In BiOS, edited by Michael R. Hamblin, Ronald W. Waynant, and Juanita Anders. SPIE, 2010. http://dx.doi.org/10.1117/12.842901.
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Weatherwax, Michele S., and Keith B. Doyle. "Vibration analysis and testing for the LLST optical module." In SPIE Optical Engineering + Applications, edited by R. Barry Johnson, Virendra N. Mahajan, and Simon Thibault. SPIE, 2014. http://dx.doi.org/10.1117/12.2063462.
Full textReports on the topic "LLHT"
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Whelan, Harry T., Michel T. Torbey, and Brendan J. Quirk. Long-wavelength Low-intensity Photon Therapy (LLPT) for Traumatic Brain Injuries. Fort Belvoir, VA: Defense Technical Information Center, September 2010. http://dx.doi.org/10.21236/ada534712.
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Lester, Peter F., and Mark W. Burton. Development of Low-Level Turbulence (LLT) Forecasting Methodologies. Fort Belvoir, VA: Defense Technical Information Center, December 1988. http://dx.doi.org/10.21236/ada208457.
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