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Journal articles on the topic 'LNA'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Xia, Ning, Depeng Wu, Xia Li, et al. "Identification of quantitative trait loci underlying fatty acid content of soybean (Glycine max), including main, epistatic and QTL×environment effects across multiple environments." Crop and Pasture Science 68, no. 9 (2017): 842. http://dx.doi.org/10.1071/cp17241.

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The uses and nutritional value of soybean (Glycine max (L.) Merrill) oil are largely influenced by the levels and relative proportions in the seed of the five major fatty acids: oleic (OA), palmitic (PA), stearic (SA), linoleic (LLA), linolenic (LNA). The present study was undertaken to identify quantitative trait loci (QTLs) that are associated with fatty acid content (particularly OA) and to determine the effects of epistasis and the environment. The mapping population included 134 recombinant inbred lines (RILs) derived from soybean varieties Suinong10 and L-9. Phenotypic data of the two pa

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2

Drais, Hayder Kadhim. "Transdermal Delivery of Lornoxicam Hybrid Nanogel: Design, Preparation, Characterization, and In-Vitro Diffusion Evaluation." Iraqi Journal of Industrial Research 10, no. 2 (2023): 98–104. http://dx.doi.org/10.53523/ijoirvol10i2id289.

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Lornoxicam was practically water insoluble and a nonsteroidal anti-inflammatory therapeutic agent thus associated with gastrointestinal tract (GIT) side effects. Lipid polymer hybrid nanocarriers (LPHNs)-based transdermal nanogel of lornoxicam was formulated to increase solubility of lornoxicam and sustained lornoxicam release that lead to eliminate GIT related side effect, prolong therapeutic activity and improve patient compliance .The lornoxicam LPHNs formulations (LH1-LH6) were prepared by microwaves based method. The conventional gel of lornoxicam (G) was prepared by solvent diffusion met

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3

Rajwanshi, Vivek K., Anders E. Håkansson, Ravindra Kumar та Jesper Wengel. "High-affinity nucleic acid recognition using ‘LNA’ (locked nucleic acid, β-D-ribo configured LNA), ‘xylo-LNA’ (β-D-xylo configured LNA) or ‘α-L-LNA’ (α-L-ribo configured LNA)". Chemical Communications, № 20 (1999): 2073–74. http://dx.doi.org/10.1039/a906713b.

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4

Wengel, Jesper, Birte Vester, Lars Bo Lundberg та ін. "LNA and α-L-LNA: Towards Therapeutic Applications". Nucleosides, Nucleotides and Nucleic Acids 22, № 5-8 (2003): 601–4. http://dx.doi.org/10.1081/ncn-120021963.

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5

Kumar, Ravindra, Sanjay K. Singh, Alexei A. Koshkin, Vivek K. Rajwanshi, Michael Meldgaard, and Jesper Wengel. "The first analogues of LNA (Locked Nucleic Acids): Phosphorothioate-LNA and 2′-thio-LNA." Bioorganic & Medicinal Chemistry Letters 8, no. 16 (1998): 2219–22. http://dx.doi.org/10.1016/s0960-894x(98)00366-7.

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6

Tsai, Ching-Han, Chun-Yi Lin, Ching-Piao Liang, Shyh-Jong Chung, and Jenn-Hwan Tarng. "Switched Low-Noise Amplifier Using Gyrator-Based Matching Network for TD-LTE/LTE-U/Mid-Band 5G and WLAN Applications." Applied Sciences 11, no. 4 (2021): 1477. http://dx.doi.org/10.3390/app11041477.

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This paper presents a triple-band low-noise amplifier (LNA) fabricated using a 0.18 μm Complementary Metal-Oxide-Semiconductor (CMOS) process. The LNA uses a double-peak load network with a switched component to accomplish the triple-band operation. Moreover, noise reduction using a substrate resistor to ameliorate the noise performance is presented. Noise reduction of 1.5 dB can be achieved at 2.5 GHz without additional dc power and extra manufacturing costs. An input matching technique is realized simultaneously using a gyrator-based feedback topology. The triple-band LNA can be realized by

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7

Rajwanshi, Vivek K., Anders E. Haakansson, Ravindra Kumar та Jesper Wengel. "ChemInform Abstract: High-Affinity Nucleic Acid Recognition Using ′LNA′ (Locked Nucleic Acid, β-D-ribo Configured LNA), ′xylo-LNA′ (β-D-xylo Configured LNA) or ′α-L-LNA′ (α-L-ribo Configured LNA)." ChemInform 31, № 5 (2010): no. http://dx.doi.org/10.1002/chin.200005250.

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8

Rashmi, Singh, and Mehra Rajesh. "Low Noise Amplifier using Darlington Pair At 90nm Technology." International Journal of Electrical and Computer Engineering (IJECE) 8, no. 4 (2018): 2054–62. https://doi.org/10.11591/ijece.v8i4.pp2054-2062.

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The demand of low noise amplifier (LNA) has been rising in today’s communication system. LNA is the basic building circuit of the receiver section satellite. The design concept demonstrates the design trade off with NF, gain, power consumption. This paper reports on with analysis of wideband LNA. This paper shows the schematic of LNA by using Darlington pair amplifier. This LNA has been fabricated on 90nm CMOS process. This paper is focused on to make comparison of three stage and single stage LNA. Here, the phase mismatch between these patameters is quantitavely analyzed to study the ef

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9

Singh, Rashmi, and Rajesh Mehra. "Low Noise Amplifier using Darlington Pair At 90nm Technology." International Journal of Electrical and Computer Engineering (IJECE) 8, no. 4 (2018): 2054. http://dx.doi.org/10.11591/ijece.v8i4.pp2054-2062.

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<p class="Abstract"><span>The demand of low noise amplifier (LNA) has been rising in today’s communication system. LNA is the basic building circuit of the receiver section satellite. The design concept demonstrates the design trade off with NF, gain, power consumption. This paper reports on with analysis of wideband LNA. This paper shows the schematic of LNA by using Darlington pair amplifier. This LNA has been fabricated on 90nm CMOS process. This paper is focused on to make comparison of three stage and single stage LNA. Here, the phase mismatch between these patameters is quant

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10

Frieden, Miriam, Henrik F. Hansen, and Troels Koch. "Nuclease Stability of LNA Oligonucleotides and LNA-DNA Chimeras." Nucleosides, Nucleotides and Nucleic Acids 22, no. 5-8 (2003): 1041–43. http://dx.doi.org/10.1081/ncn-120022731.

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11

Muhamad, Maizan, Norhayati Soin, and Harikrishnan Ramiah. "Linearity improvement of differential CMOS low noise amplifier." Indonesian Journal of Electrical Engineering and Computer Science 14, no. 1 (2019): 407. http://dx.doi.org/10.11591/ijeecs.v14.i1.pp407-412.

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<p>This paper presents the linearity improvement of differential CMOS low noise amplifier integrated circuit using 0.13um CMOS technology. In this study, inductively degenerated common source topology is adopted for wireless LAN application. The linearity of the single-ended LNA was improved by using differential structures with optimum biasing technique. This technique achieved better LNA and linearity performance compare with single-ended structure. Simulation was made by using the cadence spectre RF tool. Consuming 5.8mA current at 1.2V supply voltage, the designed LNA exhibits S<s

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12

KUMAR, R., S. K. SINGH, A. A. KOSHKIN, V. K. RAJWANSHI, M. MELDGAARD, and J. WENGEL. "ChemInform Abstract: The First Analogues of LNA (Locked Nucleic Acids): Phosphorothioate-LNA and 2′-Thio-LNA." ChemInform 29, no. 50 (2010): no. http://dx.doi.org/10.1002/chin.199850261.

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13

Charisma, Atik, Nahal Widianto, M. Reza Hidayat та Handoko Rusiana Iskandar. "Low Noise Amplifier Dual Stage dengan Metode π-Junction untuk Long Term Evolution (LTE)". TELKA - Telekomunikasi Elektronika Komputasi dan Kontrol 8, № 2 (2022): 116–25. http://dx.doi.org/10.15575/telka.v8n2.116-125.

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Long Term Evolution (LTE) merupakan teknologi tanpa kabel yang memerlukan komponen-komponen elektronika untuk mendukung performansinya. Salah satu komponen elektronika tersebut yaitu Low Noise Amplifier (LNA) sebagai penguat di bagian penerima. Penelitian ini merancamg Low Noise Amplifier dengan bantuan software berdasarkan perhitungan. LNA bekerja pada frekuensi 1,8 GHz yang merupakan pita frekuensi LTE. Tahapan perancangan LNA dimulai dari pemilihan transistor, rangkaian DC bias, dan penyesuai impedansi. Transistor ATF 34143 menjadi pilihan untuk LNA karena sesuai dengan spesifikasi yang dib

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14

Maizan, Muhamad, Hussin Hanim, and Soin Norhayati. "Design of 130nm RFCMOS differential low noise amplifier." Indonesian Journal of Electrical Engineering and Computer Science (IJEECS) 19, no. 1 (2020): 171–77. https://doi.org/10.11591/ijeecs.v19.i1.pp171-177.

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In this paper, an inductively degenerated CMOS differential low noise amplifier circuit topology is presented. This low noise amplifier is intended to be used for wireless LAN application. The differential low noise amplifier proposed provide high gain, low noise and large superior out of band IIP3. The LNA is designed in 130 nm CMOS technology. Simulated results of gain and NF at 2.4GHz are 20.46 dB and 2.59 dB, respectively. While the simulated S11 and S22 are −11.18 dB and −9.49 dB, respectively. The IIP3 is −9.05 dBm. The LNA consumes 3.4 mW power from 1.2V supply.

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15

Tomita-Sudo, Elisa, Tomoka Akita, Nae Sakimoto, Saori Tahara-Takamine, and Junji Kawakami. "Sequence-Specific Free Energy Changes in DNA/RNA Induced by a Single LNA-T Modification in Antisense Oligonucleotides." International Journal of Molecular Sciences 25, no. 24 (2024): 13240. https://doi.org/10.3390/ijms252413240.

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2′,4′-methylene bridged nucleic acid/locked nucleic acid (2′,4′-BNA/LNA; LNA) is a modified nucleic acid that improves the function of antisense oligonucleotide therapeutics. In particular, LNA in the DNA strand increases its binding affinity for the target RNA. Predicting the binding affinities of LNA-containing antisense oligonucleotides and RNA duplexes is useful for designing antisense oligonucleotides. The nearest neighbor parameters may be useful for binding affinity prediction, similar to those for natural nucleic acids. However, the sequence dependence of the thermodynamic stability of

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16

Morihara, Hirofumi, Tsuyoshi Yamamoto, Harunori Oiwa, et al. "Phospholamban Inhibition by a Single Dose of Locked Nucleic Acid Antisense Oligonucleotide Improves Cardiac Contractility in Pressure Overload-Induced Systolic Dysfunction in Mice." Journal of Cardiovascular Pharmacology and Therapeutics 22, no. 3 (2016): 273–82. http://dx.doi.org/10.1177/1074248416676392.

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Background: Phospholamban (PLN) inhibition enhances calcium cycling and is a potential novel therapy for heart failure (HF). Antisense oligonucleotides (ASOs) are a promising tool for unmet medical needs. Nonviral vector use of locked nucleic acid (LNA)-modified ASOs (LNA-ASOs), which shows strong binding to target RNAs and is resistant to nuclease, is considered to have a potential for use in novel therapeutics in the next decades. Thus, the efficacy of a single-dose injection of LNA-ASO for cardiac disease needs to be elucidated. We assessed the therapeutic efficacy of a single-dose LNA-ASO

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17

Gaurav, R. Agrawal, and A. Yelmule Leena. "Linear CMOS LNA." International Journal of Trend in Scientific Research and Development 3, no. 1 (2018): 829–35. https://doi.org/10.31142/ijtsrd19087.

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In this work, a highly linear Cascode CMOS LNA is presented. Linearity issues in RF receiver frontend are discussed, followed by an analysis of the specifications and requirements of a LNA through consideration of multi standard LNA. Device non linear characteristics cause linearity problems in the RF front end system. To solve this problem, Post linearization technique for inductively degenerated L deg common source Cascode Low Noise Amplifier is presented, which improves linearity performance with small gain loss and current consumption as consequence.The LNA presented has 1.0GHz - 3.2GHz fr

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18

Agrawal, Gaurav R., and Leena A. Yelmule. "Linear CMOS LNA." International Journal of Trend in Scientific Research and Development Volume-3, Issue-1 (2018): 829–35. http://dx.doi.org/10.31142/ijtsrd19087.

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19

Lehmeyer, Bernhard, Michel T. Ivrlač, and Josef A. Nossek. "LNA characterization methodologies." International Journal of Circuit Theory and Applications 45, no. 9 (2016): 1185–202. http://dx.doi.org/10.1002/cta.2276.

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20

CHRISTENSEN, Ulla, Nana JACOBSEN, Vivek K. RAJWANSHI, Jesper WENGEL, and Troels KOCH. "Stopped-flow kinetics of locked nucleic acid (LNA)–oligonucleotide duplex formation: studies of LNA–DNA and DNA–DNA interactions." Biochemical Journal 354, no. 3 (2001): 481–84. http://dx.doi.org/10.1042/bj3540481.

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The locked nucleic acid (LNA) monomer is a conformationally restricted nucleotide analogue with an extra 2′-O,4′-C-methylene bridge added to the ribose ring. Oligonucleotides that contain LNA monomers have shown greatly enhanced thermal stability when hybridized to complementary DNA and RNA and are considered most promising candidates for efficient recognition of a given mixed sequence in a nucleic acid duplex and as an antisense molecule. Here the kinetics and thermodynamics of a series of oligonucleotide duplex formations of DNA–DNA and DNA–LNA octamers were studied using stopped-flow absorp

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21

Manjula, S., R. Karthikeyan, S. Karthick, N. Logesh, and M. Logeshkumar. "Optimized Design of Low Power Complementary Metal Oxide Semiconductor Low Noise Amplifier for Zigbee Application." Journal of Computational and Theoretical Nanoscience 18, no. 4 (2021): 1327–30. http://dx.doi.org/10.1166/jctn.2021.9387.

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An optimized high gain low power low noise amplifier (LNA) is presented using 90 nm CMOS process at 2.4 GHz frequency for Zigbee applications. For achieving desired design specifications, the LNA is optimized by particle swarm optimization (PSO). The PSO is successfully implemented for optimizing noise figure (NF) when satisfying all the design specifications such as gain, power dissipation, linearity and stability. PSO algorithm is developed in MATLAB to optimize the LNA parameters. The LNA with optimized parameters is simulated using Advanced Design System (ADS) Simulator. The LNA with optim

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22

Rathaus, M., E. Podjarny, A. Pomeranz, J. Shapira, N. Kariv, and J. Bernheim. "Effects of sodium depletion on renal prostanoid synthesis in rats: influence of the converting enzyme inhibitor captopril." Clinical Science 76, no. 5 (1989): 469–74. http://dx.doi.org/10.1042/cs0760469.

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1. The synthesis of prostaglandin (PG) E2, PGF2α, 6-keto-PGF1α and thromboxane (TX) B2 by isolated glomeruli, cortical tubules, inner medullary slices and outer medullary slices was measured in salt-depleted (LNa) rats and in salt-depleted rats receiving captopril (LNa-CEI). Animals were studied before and after 4, 9 and 15 days of Na+ depletion. 2. Na+ balance was reached in LNa rats after 4 days. Blood pressure and creatinine clearance remained stable. Serum Na+ decreased from 140 ± 1 to 126 ± 1 mmol/l (mean ± sem, P < 0.01). In contrast, LNa-CEI rats were unable to conserve Na+ adequatel

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23

Zhang, Yu, Shu Hui Yang, and Yin Chao Chen. "Design and Simulation of a 5.8GHz Low Noise Amplifier Used in RFID." Applied Mechanics and Materials 441 (December 2013): 133–36. http://dx.doi.org/10.4028/www.scientific.net/amm.441.133.

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A 5.8GHz single-stage low noise amplifier (LNA) for radio frequency identification devices (RFID) applications was proposed according to the theory of LNA. It has been realized by ATF-541M4 transistor and its peripheral circuit, such as bias circuit, input and output matching network. The proposed LNA provides a gain of 12.696dB from the analysis of ADS. The LNA achieves 0.951dB noise figure (NF) at the frequency of 5.8GHz. The simulation results show that this LNA has good noise characteristic, the NF is less than other published paper.

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24

Yousef, K., H. Jia, R. Pokharel, et al. "CMOS Ultra-Wideband Low Noise Amplifier Design." International Journal of Microwave Science and Technology 2013 (April 30, 2013): 1–6. http://dx.doi.org/10.1155/2013/328406.

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This paper presents the design of ultra-wideband low noise amplifier (UWB LNA). The proposed UWB LNA whose bandwidth extends from 2.5 GHz to 16 GHz is designed using a symmetric 3D RF integrated inductor. This UWB LNA has a gain of 11 ± 1.0 dB and a NF less than 3.3 dB. Good input and output impedance matching and good isolation are achieved over the operating frequency band. The proposed UWB LNA is driven from a 1.8 V supply. The UWB LNA is designed and simulated in standard TSMC 0.18 µm CMOS technology process.

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25

Zhou, Shaohua, and Jian Wang. "An Experimental Investigation of the Degradation of CMOS Low-Noise Amplifier Specifications at Different Temperatures." Micromachines 13, no. 8 (2022): 1268. http://dx.doi.org/10.3390/mi13081268.

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To investigate the relationship between the specifications degradation of a low-noise amplifier (LNA) and temperature, we experimentally investigated the degradation characteristics of the specifications of the LNA at different temperatures. The small-signal gain (S21) of the LNA decreases with increasing temperature. This paper discusses and analyzes the experimental results in detail, and the reasons for the degradation of LNA specifications with temperature changes are known. Finally, we have tried to use the structure already available in the literature for the PA temperature compensation

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26

Bouhouche, Manel, and Saida Latreche. "Single Event Effect Analysis of SiGe Low Noise Amplifier." Electronics ETF 25, no. 2 (2021): 57–64. http://dx.doi.org/10.53314/els2125057b.

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This paper analyzes the single event transient (SET) response of low noise amplifier (LNA) designed using SiGe heterojunction bipolar transistors (HBT). To verify the radiation tolerance of the proposed LNA, a total of four cascode configurations were designed. Comprehensive mixed-mode simulations were performed to evaluate the SET susceptibility of considered LNA cascode configurations, and we have analyzed how the strike parameters affect their output response. In this fact the strike position, linear energy transfer (LET), and track radius, were varied, and the resulting transients were com

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27

Arıcan, Galip Orkun, and Burak Alptuğ Yılmaz. "Analysis and Design of a W-Band MMIC LNA with 4.2 dB Noise Figure in GaAs-based 100 nm pHEMT Technology." Gazi University Journal of Science Part A: Engineering and Innovation 12, no. 2 (2025): 603–14. https://doi.org/10.54287/gujsa.1662033.

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A W-band Monolithic Microwave Integrated Circuit (MMIC) Low Noise Amplifier (LNA) is presented in this paper. The UMS PH10 process, which is the GaAs/InGaAs based pseudomorphic High Electron Mobility Transistors (pHEMTs) technology, is utilized to design the proposed W-band MMIC LNA. The proposed LNA has a simulated noise figure (NF) of 4.2 dB in the operating frequency range from 94 to 104 GHz while the simulated minimum noise figure (NFmin) of 3.9 dB at the center frequency. Besides, proposed W-band MMIC LNA has very good reflection loss performance, well below -10 dB and high small signal g

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28

Teguh, Firmansyah, Suryo Pramudyo Anggoro, Wardoyo Siswo, Wiryadinata Romi, and Alimuddin. "Concurrent Quad-band Low Noise Amplifier (QB-LNA) using Multisection Impedance Transformer." International Journal of Electrical and Computer Engineering (IJECE) 7, no. 4 (2017): 2061–70. https://doi.org/10.11591/ijece.v7i4.pp2061-2070.

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A quad-band low noise amplifier (QB-LNA) based on multisection impedance transformer designed and evaluated in this research. As a novelty, a multisection impedance transformer was used to produce QB-LNA. A multisection impedance transformer is used as input and output impedance matching because it has higher stability, large Q factor, and low noise than lumpedcomponent.The QB-LNA was designed on FR4 microstrip substrate with r= 4.4, thickness h=1.6 mm, and tan = 0.026. The proposed QB-LNA was designed and analyzed by Advanced Design System (ADS).The simulation has shown that QB-LNA achieves

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29

Agarwal, Nitin, Manish Gupta, and Manish Kumar. "AN EXTENSIVE REVIEW ON: LOW NOISE AMPLIFIER FOR MILLIMETER AND RADIO FREQUENCY WAVES." Jurnal Teknologi 84, no. 1 (2021): 231–39. http://dx.doi.org/10.11113/jurnalteknologi.v84.16524.

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In today’s world, radio receiver system is a prevailing wireless technology in that the major part is Low Noise Amplifier (LNA) which widely used to improve weak signals in many applications with millimeter and radio frequency waves such as optical communication, multimode transceivers and measurement instrumentations. The real drawbacks of LNA is that it fails to maintain specific properties in critical conditions like as minimum power consumption, provide low noise figure, input matching and linearity. Additionally, promoted by various application demands, design methods and control methods

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30

Muhamad, Maizan, Hanim Hussin, and Norhayati Soin. "Design of 130nm RFCMOS differential low noise amplifier." Indonesian Journal of Electrical Engineering and Computer Science 19, no. 1 (2020): 172. http://dx.doi.org/10.11591/ijeecs.v19.i1.pp172-177.

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<span>In this paper, an inductively degenerated CMOS differential low noise amplifier circuit topology is presented. This low noise amplifier is intended to be used for wireless LAN application. The differential low noise amplifier proposed provide high gain, low noise and large superior out of band IIP3. The LNA is designed in 130 nm CMOS technology. Simulated results of gain and NF at 2.4GHz are 20.46 dB and 2.59 dB, respectively. While the simulated S<sub>11</sub> and S<sub>22</sub> are −11.18 dB and −9.49 dB, respectively. The IIP3 is −9.05 dBm. The LNA consum

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31

Petersen, Michael, Jakob T. Nielsen, Kent Bondensgaard, Jesper Wengel та Jens Peter Jacobsen. "Structural Characterization of LNA and α-L-LNA Hybridized to RNA". Nucleosides, Nucleotides and Nucleic Acids 22, № 5-8 (2003): 1691–93. http://dx.doi.org/10.1081/ncn-120023115.

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32

Szekely, Laszlo, Csaba Kiss, Karin Mattsson, et al. "Human herpesvirus-8-encoded LNA-1 accumulates in heterochromatin- associated nuclear bodies." Journal of General Virology 80, no. 11 (1999): 2889–900. http://dx.doi.org/10.1099/0022-1317-80-11-2889.

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Subnuclear distribution of the human herpesvirus-8 (HHV-8)- encoded nuclear protein LNA-1 was analysed at high resolution in body cavity (BC) lymphoma-derived cell lines, in cell hybrids between BC cells and various human and mouse cells and in freshly infected K562 and ECV cell lines. Three-dimensional reconstruction of nuclei from optical sections and quantitative analysis of the distribution of LNA-1 fluorescence in relation to chromatin showed that LNA-1 associates preferentially with the border of heterochromatin in the interphase nuclei. This was further confirmed in the following system

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33

Okamoto, Shunsuke, Yusuke Echigoya, Ayaka Tago, Takao Segawa, Yukita Sato, and Takuya Itou. "Antiviral Efficacy of RNase H-Dependent Gapmer Antisense Oligonucleotides against Japanese Encephalitis Virus." International Journal of Molecular Sciences 24, no. 19 (2023): 14846. http://dx.doi.org/10.3390/ijms241914846.

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RNase H-dependent gapmer antisense oligonucleotides (ASOs) are a promising therapeutic approach via sequence-specific binding to and degrading target RNAs. However, the efficacy and mechanism of antiviral gapmer ASOs have remained unclear. Here, we investigated the inhibitory effects of gapmer ASOs containing locked nucleic acids (LNA gapmers) on proliferating a mosquito-borne flavivirus, Japanese encephalitis virus (JEV), with high mortality. We designed several LNA gapmers targeting the 3’ untranslated region of JEV genomic RNAs. In vitro screening by plaque assay using Vero cells revealed t

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34

Kubota, Kengo, Akiyoshi Ohashi, Hiroyuki Imachi, and Hideki Harada. "Improved In Situ Hybridization Efficiency with Locked-Nucleic-Acid-Incorporated DNA Probes." Applied and Environmental Microbiology 72, no. 8 (2006): 5311–17. http://dx.doi.org/10.1128/aem.03039-05.

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ABSTRACT Low signal intensity due to poor probe hybridization efficiency is one of the major drawbacks of rRNA-targeted in situ hybridization. There are two major factors affecting the hybridization efficiency: probe accessibility and affinity to the targeted rRNA molecules. In this study, we demonstrate remarkable improvement in in situ hybridization efficiency by applying locked-nucleic-acid (LNA)-incorporated oligodeoxynucleotide probes (LNA/DNA probes) without compromising specificity. Fluorescently labeled LNA/DNA probes with two to four LNA substitutions exhibited strong fluorescence int

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35

Ma, Zhenyang, Jiahao Liu, Zhaobin Duan, Chunlei Shi, and Shaonan He. "Analysis of Indirect Lightning Effects on Low-Noise Amplifier and Protection Design." Electronics 12, no. 24 (2023): 4912. http://dx.doi.org/10.3390/electronics12244912.

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In order to analyze the interference mechanisms of indirect lightning effects on a low-noise amplifier (LNA), a circuit model of the LNA was constructed based on the advanced design system 2020 (ADS 2020) software. Lightning pulse injection simulations were conducted to explore the influence of lightning pulses on the performance of the LNA. A pin injection test was performed to investigate the interference and damage threshold of the LNA. A protective circuit incorporating the transient voltage suppressor (TVS) and Darlington structure was designed through simulation, employing the ADS 2020 f

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36

Nguyen Huu Tho. "A 1.8 to 4 GHz inductor-less highly linear CMOS LNA for wire-less receivers." Journal of Military Science and Technology, no. 76 (December 12, 2021): 11–20. http://dx.doi.org/10.54939/1859-1043.j.mst.76.2021.11-20.

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This paper presents an inductor-less wide-band highly linear low-noise amplifier (LNA) for wire-less receivers. The inductor-less LNA consists of a complementary current-reuse common source ampliﬁer combined with a low-current active feedback to obtain wide range input impedance matching and low noise figure. In our LNA, a degeneration resistor is utilized to improve linearity of the LNA. Furthermore, we designed a bypass mode for the LNA to extend the range of its applications. The proposed LNA is implemented in 28 nm CMOS process. It has a gain of 14.9 dB and a bandwidth of 2.2 GHz. The nois

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37

Han, Fang, Xuzhi Liu, Chao Wang, et al. "A Multi-Band LNA Covering 17–38 GHz in 45 nm CMOS SOI." Electronics 11, no. 19 (2022): 3255. http://dx.doi.org/10.3390/electronics11193255.

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This paper presents a multi-band low-noise amplifier (LNA) in the 45-nm CMOS silicon-on-insulator (SOI) process. The LNA consists of three stages, with the differential cascode amplifier as the core structure. The first stage is mainly responsible for input matching to ensure favourable noise characteristics and bandwidth, while the subsequent stages increase the gain. Moreover, the LNA utilizes baluns for input/output and interstage impedance matching. Switch capacitances are added to switch the three operating bands of the LNA, which cover 17–38 GHz overall. Measurement results show that the

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Uzzal, Mohammad Mohiuddin. "Design, simulation and optimization of a single stage Low Noise Amplifier (LNA) for very low power L- Band satellite handheld applications." AIUB Journal of Science and Engineering (AJSE) 17, no. 2 (2018): 37–42. http://dx.doi.org/10.53799/ajse.v17i2.7.

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In first stage of each microwave receiver, there is a Low Noise Amplifier (LNA) stage, and this LNA plays an important role to determine the quality factor of the receiver. The design of a LNA requires the trade-off of many important parameters including gain, Noise Figure (NF), stability, power consumption, cost and design complexity. In this paper, we have designed and simulate a single stage stable LNA circuit having gain 11.78 dB and noise figure 1.86 dB using microwave BJT AT3103 with Agilent package Advance Design Systems (ADS). This LNA operates at center frequency of 2 GHZ and it can b

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Mathis, K. M., and R. O. Banks. "Role of nitric oxide and angiotensin II in diabetes mellitus-induced glomerular hyperfiltration." Journal of the American Society of Nephrology 7, no. 1 (1996): 105–12. http://dx.doi.org/10.1681/asn.v71105.

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The goal of this study was to determine what extent nitric oxide (NO) and/or angiotensin II (AngII) are involved in the hyperfiltration observed in rats with streptozotocin-induced diabetes mellitus. Studies were performed on anesthetized rats 7 to 10 days after the induction of diabetes. Nitro-L-arginine (LNA) was used to inhibit NO synthesis, and losartan was used to block AngII receptors. Three protocols were utilized: (i) control and diabetic rats treated with a constant infusion of LNA; (ii) control and diabetic rats treated first with a constant infusion of losartan and then LNA plus los

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Zhang, Yong, Aldo M. Roccaro, Oliver Broom, et al. "LNA Anti-Microrna-155: a Novel Therapeutic Strategy In Waldenstrom Macroglobulinemia and Chronic Lymphocytic Leukemia." Blood 116, no. 21 (2010): 4914. http://dx.doi.org/10.1182/blood.v116.21.4914.4914.

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Abstract Abstract 4914 Background. We and others have previously demonstrated that microRNA-155 (miR-155) is overexpressed in patients with Waldenstrom's Macroglobulinemia (WM) and Chronic lymphocytic leukemia (CLL) compared to healthy subjects; indicating that miR-155 may play a crucial role in regulating the pathogenesis of these diseases. We therefore evaluated the role of the novel locked nucleic acid (LNA) antimiR against miR-155 in WM and CLL-derived cell lines. Methods. WM and CLL-derived cell lines (BCWM.1, MEC1) have been treated with 20μM antisense LNA antimiR-155 or scramble probe (

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Malmqvist, R., C. Samuelsson, A. Gustafsson, et al. "A K-Band RF-MEMS-Enabled Reconfigurable and Multifunctional Low-Noise Amplifier Hybrid Circuit." Active and Passive Electronic Components 2011 (2011): 1–7. http://dx.doi.org/10.1155/2011/284767.

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A K-band (18–26.5 GHz) RF-MEMS-enabled reconfigurable and multifunctional dual-path LNA hybrid circuit (optimised for lowest/highest possible noise figure/linearity, resp.) is presented, together with its subcircuit parts. The two MEMS-switched low-NF (higher gain) and high-linearity (lower gain) LNA circuits (paths) present 16.0 dB/8.2 dB, 2.8 dB/4.9 dB and 15 dBm/20 dBm of small-signal gain, noise figure, and 1 dB compression point at 24 GHz, respectively. Compared with the two (fixed) LNA subcircuits used within this design, the MEMS-switched LNA circuit functions show minimum 0.6–1.3 dB hi

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Kellam, Paul, Dimitra Bourboulia, Nicolas Dupin, et al. "Characterization of Monoclonal Antibodies Raised against the Latent Nuclear Antigen of Human Herpesvirus 8." Journal of Virology 73, no. 6 (1999): 5149–55. http://dx.doi.org/10.1128/jvi.73.6.5149-5155.1999.

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ABSTRACT Human herpesvirus 8 (HHV-8; also designated Kaposi’s sarcoma-associated herpesvirus) is the likely etiological agent of Kaposi’s sarcoma (KS). HHV-8 encodes a latent nuclear antigen (LNA) which is the product of the viral gene orf 73. LNA is recognized by most infected patient sera and is the basis of current immunofluorescence assays used in epidemiological studies of HHV-8 infection. Here we describe the characterization of four monoclonal antibodies raised to the C-terminal third of LNA–glutathioneS-transferase fusion proteins. These monoclonal antibodies recognized discrete linear

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Saurabh, Pargaien*, Singh Bist Ankur, Sharma Rudranshu, and Patrick Anubhav. "A REVIEW OF 2.4 GHZ LNA USING DIFFERENT TOPOLOGIES IN STANDARD CMOS." INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & RESEARCH TECHNOLOGY 5, no. 4 (2016): 373–78. https://doi.org/10.5281/zenodo.49705.

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This paper presents the literature review of various designs of LNA using different topologies. Designing very high-performance LNAs is an active research area and is of crucial importance for wireless technologies. CMOS LNA architectures can be divided into two major groups the common source and the common gate LNA. CS LNA output gate current noise increases with the increase in frequency. In CGLNA noise factor is nearly constant irrespective of the frequency of operation and bandwidth.  

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Bao, Kuan, and Xiang Ning Fan. "An ESD Protected Wideband CMOS Low Noise Amplifier Employing Active Feedback Technique." Advanced Materials Research 403-408 (November 2011): 2809–13. http://dx.doi.org/10.4028/www.scientific.net/amr.403-408.2809.

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This paper presents a wideband low noise amplifier (LNA) for multi-standard radio applications. The low noise characteristic and input matching are simultaneously achieved by active-feedback technique. Bond-wire inductors and electrostatic devices (ESDs) are co-designed to improve the chip performance. Implemented in 0.18-μm CMOS process, the core size of the fully integrated LNA circuits is 535 μm×425 μm without any passive on-chip inductor. The simulated gain and the minimal noise figure of the CMOS LNA are 17.5 dB and 2.0 dB, respectively. The LNA achieves a -3dB bandwidth of 3.1 GHz. And t

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Di Martino, Maria Teresa, Mariamena Arbitrio, Massimiliano Fonsi, et al. "Allometric Scaling Approaches for Predicting Human Pharmacokinetic of a Locked Nucleic Acid Oligonucleotide Targeting Cancer-Associated miR-221." Cancers 12, no. 1 (2019): 27. http://dx.doi.org/10.3390/cancers12010027.

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LNA-i-miR-221 is a novel phosphorothioate backbone 13-mer locked nucleic acid oligonucleotide-targeting microRNA-221 designed for the treatment of human malignancies. To understand the pharmacokinetic properties of this new agent, including unbound/total clearance, we investigated the LNA-i-miR-221 protein binding in three different species, including rat (Sprague–Dawley), monkey (Cynomolgus), and human. To this end, we generated a suitable ultrafiltration method to study the binding of LNA-i-miR-221 to plasma proteins. We identified that the fraction of LNA-i-miR-221 (at concentration of 1 an

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Zhang, Yong, Christopher P. Rombaoa, Aldo M. Roccaro, et al. "LNA Anti-MicroRNA-155: A Novel Therapeutic Strategy in Waldenstrom Macroglobulinemia and Chronic Lymphocytic Leukemia." Blood 118, no. 21 (2011): 2728. http://dx.doi.org/10.1182/blood.v118.21.2728.2728.

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Abstract Abstract 2728 Background. We and others have previously demonstrated that primary Waldenstrom's Macroglobulinemia (WM) and Chronic lymphocytic leukemia (CLL) cells show increased expression of microRNA-155 (miR-155), suggesting a role in regulating pathogenesis and tumor progression of these diseases. However, developing therapeutic agents that specifically target miRNAs has been hampered by the lack of appropriate delivery of small RNA inhibitors into tumor cells. We tested the effect of a novel LNA (locked nucleic acid)-modified anti-miR-155 in WM and CLL. Methods. WM and CLL cells,

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Warshawsky, Ilka, and Frank Mularo. "Locked nucleic acid probes for enhanced detection of FLT3 D835/I836, JAK2 V617F and NPM1 mutations." Journal of Clinical Pathology 64, no. 10 (2011): 905–10. http://dx.doi.org/10.1136/jclinpath-2011-200086.

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AimsDetecting low-level clinically significant cancer-relevant somatic mutations can be difficult. Several technologies exist for detecting minority mutations. One method is locked nucleic acid (LNA) PCR. In this study, LNA probes were used to enhance the sensitivity for detecting FLT3 D835/I836 tyrosine kinase domain (TKD) mutations, the JAK2 V617F mutation and insertion mutations in the nucleophosmin 1 gene.MethodsPCR was performed with and without LNA probes using DNA known to contain FLT3 D835/I836 TKD, JAK2 V617F and NPM1 mutations. FLT3 D835/I836 TKD mutations were detected following Eco

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ROY, NILADRI, GARRETT MCCORMICK, VIJAY DEVABHAKTUNI, and RABIN RAUT. "A SYSTEMATIC COMPUTER-AIDED APPROACH TO LOW-NOISE AMPLIFIER DESIGN." Journal of Circuits, Systems and Computers 19, no. 06 (2010): 1163–79. http://dx.doi.org/10.1142/s0218126610006803.

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Low-noise amplifiers (LNAs) are critical to a wide variety of electronic circuits. In the design phase preceding fabrication, an LNA needs to be designed for a given set of specifications (e.g., gain, noise-figure, power consumption, etc.), which tend to be application-dependent. Typically, LNA design using commercial computer-aided design (CAD) tools can be human-intensive and requires a certain degree of expertise. This paper presents a systematic multi-phase CAD approach for the design of LNAs. In the first phase, a quick pre-analysis of the given LNA specifications is carried out leading t

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Guo, Zifeng, and Jian Liu. "A Ku band low-voltage and low-power CMOS low-noise amplifier with bulk isolation techniques." Journal of Electrical Engineering 75, no. 2 (2024): 102–12. http://dx.doi.org/10.2478/jee-2024-0014.

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Abstract In this paper, a broadband(12-18G) low-noise amplifier (LNA) using 65-nm CMOS technology for satellite communication is presented. This LNA was designed in a cascode common source with inductive degeneration topology. In addition, the bulk isolation technique is employed to make the proposed LNA have a higher gain. Furthermore, a two-stage cascaded configuration combined with inductive parallel peaking technology is utilized to make the LNA achieve a wide operating band. For validation, we design this LNA in a 65nm CMOS technology. The simulated results show that S21 of 17.7dB ± 0.5dB

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Xiang, Yong, Yan Bin Luo, Ren Jie Zhou, and Cheng Yan Ma. "A Low Noise Amplifier with 1.1dB Noise Figure and +17dBm OIP3 for GPS RF Receivers." Applied Mechanics and Materials 336-338 (July 2013): 1490–95. http://dx.doi.org/10.4028/www.scientific.net/amm.336-338.1490.

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A 1.575GHz SiGe HBT(heterojunction bipolar transistor) low-noise-amplifier(LNA) optimized for Global Positioning System(GPS) L1-band applications was presented. The designed LNA employed a common-emitter topology with inductive emitter degeneration to simultaneously achieve low noise figure and input impedance matching. A resistor-bias-feed circuit with a feedback resistor was designed for the LNA input transistor to improve the gain compression and linearity performance. The LNA was fabricated in a commercial 0.18µm SiGe BiCMOS process. The LNA achieves a noise figure of 1.1dB, a power gain o

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