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1

Dr, P. Lekha Priyadharshini, and V. Jayaraman Dr. "Effects of low Doses of Intrathecal Clonidine and Dexmedetomidine with Bupivacaine on The Duration of Sensory and Motor Block in Abdominal and Lower Limb Surgeries- A Prospective Randomised Double Blinded Study." INTERNATIONAL JOURNAL OF HEALTH & MEDICAL RESEARCH 03, no. 05 (2024): 170–80. https://doi.org/10.5281/zenodo.11097651.

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BACKGROUND: The purpose of this study is to compare the duration of sensory and motor block in  elective lower limb and abdominal procedures following intrathecal administration of bupivacaine along with adjuvants either clonidine or dexmedetomidine.METHODS: A prospective randomised double blinded study. 120 study participants were randomly allocated to three groups-Group A was given 12.5 mg of hyperbaric bupivacaine, Group B was given 3 mcg dexmedetomidine along with 12.5 mg hyperbaric bupivacaine and Group C was given 30 mcg of clonidine along with hyperbaric bupivacaine. The duration o
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Zhang, Guorong, Xiaosai Hou, Haonan Wang, Chaoqian Han, and Dongsheng Fan. "Infraclavicular versus supraclavicular nerve block for upper limb surgeries: A meta-analysis." Medicine 103, no. 43 (2024): e40152. http://dx.doi.org/10.1097/md.0000000000040152.

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Background: The impact of infraclavicular versus supraclavicular nerve block on the analgesia for upper limb surgeries is unclear. This meta-analysis and systematic review aims to study the analgesic efficacy of infraclavicular versus supraclavicular nerve block for upper limb surgeries. Methods: We searched several databases including PubMed, EMbase, Web of science, EBSCO and Cochrane library databases from inception to December 2023, and randomized controlled trials (RCTs) assessing the effect of infraclavicular versus supraclavicular nerve block for upper limb surgeries were included. We ex
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Reale, Davide, Luca Andriolo, Safa Gursoy, Murat Bozkurt, Giuseppe Filardo, and Stefano Zaffagnini. "Complications of Tranexamic Acid in Orthopedic Lower Limb Surgery: A Meta-Analysis of Randomized Controlled Trials." BioMed Research International 2021 (January 16, 2021): 1–14. http://dx.doi.org/10.1155/2021/6961540.

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Objective. Tranexamic acid (TXA) is increasingly used in orthopedic surgery to reduce blood loss; however, there are concerns about the risk of venous thromboembolic (VTE) complications. The aim of this study was to evaluate TXA safety in patients undergoing lower limb orthopedic surgical procedures. Design. A meta-analysis was performed on the PubMed, Web of Science, and Cochrane Library databases in January 2020 using the following string (Tranexamic acid) AND ((knee) OR (hip) OR (ankle) OR (lower limb)) to identify RCTs about TXA use in patients undergoing every kind of lower limb surgical
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Uglow, Michael, Michael Ribeiro, Simone Battibugli, Ahmed Hammouda, and Rachel Herbert. "DELAYED HEALING TIME OF CHRONICALLY INFECTED OPEN FRACTURES FROM WAR ZONE INJURIES IN CHILDREN." Orthopaedic Proceedings 107-B, SUPP_3 (2025): 21. https://doi.org/10.1302/1358-992x.2025.3.021.

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Forty eight patients aged under 18yrs suffered a total of 55 limb segment injuries and were admitted to a single institution. There were 3 amputations involving the upper limb, 6 amputations involving the lower limb at a level above the ankle and 6 partial amputations involving the foot. There were 15 femoral fractures, 12 tibial fractures, and 7 fractures of the foot. There were 6 upper limb fractures. 92.5% of the fractures were open, all Gustilo & Anderson Grade 3a, 3b & 3c. Most patients had received emergency care at the country of origin including wound cleaning, application of t
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LEE, Hyon Ju. "Prosthetics, Medicine, and Disability in Modern America: The Case of the A. A. Marks Artificial Limb Company." Korean Journal of Medical History 32, no. 1 (2023): 33–80. http://dx.doi.org/10.13081/kjmh.2023.32.33.

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Through the case of the A. A. Marks Artificial Limb Company, this article explores how the technology and business of prosthetics grew in America up to the First World War. In 1853, Amasa A. Marks established the artificial limb company A. A. Marks in New York. By the time of the First World War, the company had become the largest supplier of artificial limbs in the United States and had gained international recognition, exporting its products all over the world. Focusing on the company’s growth before the war, this paper analyzes how American artificial limb makers positioned themselves betwe
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GAIBOV, A. D., O. NEMATZODA, D. D. SULTANOV, K. A. ABDUSAMADOV, SH A. SHOKHSAVORBEKOV, and A. K. BARATOV. "ENDOVASCULAR REVASCULARIZATION METHODS IN THE TREATMENT OF ACUTE LOWER LIMB ISCHEMIA: THE CURRENT STATE OF KNOWLEDGE." AVICENNA BULLETIN 27, no. 1 (2024): 155–69. https://doi.org/10.25005/2074-0581-2025-27-1-155-169.

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Objective: To determine the role and significance of endovascular revascularization methods in treating acute lower limb ischemia (ALLI) from the perspective of modern literature. Materials and methods: A literature search was conducted on publications in Russian and English at the medical literature platforms on endovascular methods used in the treatment of ALLI. The search was performed in PubMed, Google Scholar, Web of Science, Cochrane.org, CyberLeninka.ru, and eLibrary.ru databases over the past 10 years (except for one historical study from 1994). The key search terms included: acute low
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Piekarska, Ewa, Krzysztof Dobrzeniecki, and Remigiusz Luter. "Invasive Treatment of Lower Limb Varicose Veins - Comparison of Treatment Methods." Journal of Education, Health and Sport 77 (January 3, 2025): 56646. https://doi.org/10.12775/jehs.2025.77.56646.

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Introduction and objective: Varicose veins in the lower extremities are a clinical manifestation of chronic venous disease. The condition is highly prevalent, with incidence increasing with age. Varicose veins are often accompanied by pain, and neglecting treatment can lead to complications such as superficial vein inflammation, deep vein thrombosis, and, most critically, pulmonary embolism. The primary aim of this study was to analyze and compare the efficacy and safety of available contemporary invasive methods for treating varicose veins in the lower extremities. Additionally, this paper ad
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Xu, Chunlei, Anning Wang, Dong Li, Huafeng Zhang, Hui Li, and Zhijun Li. "Global trends in research of venous thromboembolism associated with lower limb joint arthroplasty: A bibliometric analysis." Medicine 103, no. 25 (2024): e38661. http://dx.doi.org/10.1097/md.0000000000038661.

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This study aims to visualize publications related to venous thromboembolism (VTE) and lower limb joint arthroplasty to identify research frontiers and hotspots, providing references and guidance for further research. We retrieved original articles published from 1985 to 2022 and their recorded information from the Web of Science Core Collection. The search strategy used terms related to knee or hip arthroplasty and thromboembolic events. Microsoft Excel was used to analyze the annual publications and citations of the included literature. The rest of the data were analyzed using the VOSviewer,
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Pertea, Mihaela, Stefana Luca, Dan Cristian Moraru, et al. "Upper Limb Compartment Syndrome—An Extremely Rare Life-Threatening Complication of Cutaneous Anthrax." Microorganisms 12, no. 6 (2024): 1240. http://dx.doi.org/10.3390/microorganisms12061240.

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(1) Background: Cutaneous anthrax is a disease caused by a Gram-positive bacillus, spore-forming Bacillus anthracis (BA). Cutaneous anthrax accounts for 95% of all anthrax cases, with mortality between 10–40% in untreated forms. The most feared complication, which can be life-threatening and is rarely encountered and described in the literature, is compartment syndrome. (2) Methods: We report a series of six cases of cutaneous anthrax from the same endemic area. In two of the cases, the disease was complicated by compartment syndrome. The systematic review was conducted according to systematic
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Cursino Fernandes, Milena Peloggia, Noé De Marchi Neto, Ricardo Cardenuto Ferreira, Marco Tulio Costa, Jordanna Bergamasco, and Daiana Gobbo. "PO 18122 - Treatment of Charcot arthropathy in the ankle joint." Scientific Journal of the Foot & Ankle 13, Supl 1 (2019): 21S. http://dx.doi.org/10.30795/scijfootankle.2019.v13.998.

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Introduction: Charcot arthropathy can lead to joint destruction and often causes ulcers at sites of bony prominences. In the ankle, it causes instability that limits gait and makes it difficult for patients to wear shoes or orthoses. This was a retrospective study describing cases of Charcot arthropathy of the ankle treated at our institution from 1997 to 2017. Methods: Over the study period, we treated 252 patients with Charcot arthropathy. Of these patients, 27 presented the disease exclusively in the ankle. The selected cases were unilateral; 17 of the patients were men, and the mean age wa
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Matta-Gutiérrez, Gianmarco, Esther García-Morales, Yolanda García-Álvarez, Francisco Javier Álvaro-Afonso, Raúl Juan Molines-Barroso, and José Luis Lázaro-Martínez. "The Influence of Multidrug-Resistant Bacteria on Clinical Outcomes of Diabetic Foot Ulcers: A Systematic Review." Journal of Clinical Medicine 10, no. 9 (2021): 1948. http://dx.doi.org/10.3390/jcm10091948.

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Multidrug-resistant organism infections have become important in recent years due to the increased prevalence of diabetic foot ulcers and their possible consequences. This study aimed to systematically review and evaluate ulcer duration, healing time, hospital stay, amputation, and mortality rates in patients with diabetic foot ulcers caused by infection with multidrug-resistant organisms. PubMed, the Cochrane Library, and Web of Science were searched in May 2020 to find observational studies in English about the clinical outcomes of multidrug-resistant organism infection in diabetic foot ulce
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Singh, Rajpal, Shobha Chamania, Appikonda Naga Jaswanth, and Saumya Singh. "Choithram’s Modified Hanging Limb Preparation for Limb Surgeries." Journal of Surgical Specialties and Rural Practice 5, no. 1 (2024): 27–28. http://dx.doi.org/10.4103/jssrp.jssrp_5_24.

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Abstract In an extensive lower limb burn surgery, where we need to operate circumferentially, we need to have a hanging limb preparation to have exposure to all sides of the leg. Here, we describe a modified method of limb holding described by authors from a paper published by Farroha et al. in EJPS, 2013. In our setup, we hang the lower limb using sharp towel clips, fixed to the patient’s great toe at distal phalanx (DP). These towel clips are elevated by a sterile bandage to the hook of intravenous stand, which is stabilized using weights on the other end. We are using this method for lower
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13

Thangarasu, Satva, and Ashish Bangari. "PRE-EMPTIVE ANALGESIA WITH PREGABALIN IN ELECTIVE LOWER LIMB ORTHOPAEDIC SURGERIES: A RANDOMIZED CONTROLLED TRIAL." International Journal of Advanced Research 13, no. 05 (2025): 146–51. https://doi.org/10.21474/ijar01/20887.

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Background: Postoperative pain in orthopaedic surgeries, particularly lower limb procedures, is severe and can delay rehabilitation. Pre-emptive analgesia aims to prevent central sensitization by administering analgesics before surgical injury. Objective: To evaluate the efficacy of pre-emptive pregabalin in reducing postoperative pain and opioid consumption in elective lower limb orthopaedic surgeries. Methods: A randomized, double-blind, placebo-controlled trial enrolled 60 patients undergoing elective lower limb orthopaedic surgeries. Patients received pregabalin (150 mg) or placebo one hou
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Asma, Shafique, Ashraf Ambreen, Parashar Mani, Dev Jagar Keshav, and Kumar Lal Sanjay. "A Comparative Study on Efficacy of Intrathecal Bupivacaine Heavy with Fentanyl and Intrathecal Levobupivacaine Heavy with Fentanyl for Lower Limb and Lower Abdominal Surgeries." International Journal of Pharmaceutical and Clinical Research 16, no. 12 (2024): 532–40. https://doi.org/10.5281/zenodo.14593469.

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<strong>Introduction:&nbsp;</strong>A study comparing the anaesthetic effect of hyperbaric bupivacaine with fentanyl and hyperbaric levobupivacaine with fentanyl for lower limb and lower abdominal surgeries was conducted.&nbsp;<strong>Methods:&nbsp;</strong>A study involving 100 patients underwent lower limb and abdominal surgeries, divided into two groups (A and B) and administered hyperbaric bupivacaine with fentanyl or levobupivacaine with fentanyl.&nbsp;<strong>Results:</strong>&nbsp;Statistical analysis showed no significant differences in hemodynamic parameters or side effects between th
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Straszewski, Dariusz, Marcin Plenzler, Joanna Szczepaniak, et al. "MRI Evaluation of Patella Alignment Before and After Anatomical Reconstruction of ACL Undergoing Unified Rehabilitation Programme Introduced by CMC Physical Therapy Team." Orthopaedic Journal of Sports Medicine 2, no. 11_suppl3 (2014): 2325967114S0014. http://dx.doi.org/10.1177/2325967114s00148.

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Objectives: The aim of the study was to asses the impact of the functional rehabilitation on patella alignment with MRI imaging in patients who underwent the ACL reconstruction. The surgical approach with the use of patellar tendon graft is known to carry the risk of lowering patella height (patella baja), which, in turn, may lead to accelerated cartilage wear in patellofemoral joint. Methods: 30 patients after the anatomical reconstruction of ACL took part in this study (23 male, and 7 female, mean age = 28 ± 10,6 years). During the procedure a patellar tendon graft was used. The Insali-Salva
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Thakur, Kunwar Singh, Utsav Sharma, Preeti Goyal, and Bhanu Choudhary. "The Study Isobaric 0.75% Ropivacaine 3.5ml (26.25mg) Intrathecally for Lower Limb Surgeries to Evaluate Perioperative Hemodynamic Stability." Academia Anesthesiologica International 5, no. 1 (2020): 168–70. http://dx.doi.org/10.21276/aan.2020.5.1.35.

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Background: The purpose of the study is Isobaric 0.75% Ropivacaine 3.5ml (26.25mg) Intrathecally for Lower Limb Surgeries to Evaluate Perioperative Hemodynamic. Fifty patients admitted to our hospital undergoing lower extremity surgeries under spinal anesthesia. Subjects and Methods: Pre-anesthetic assessment was done prior to the day of surgery which included past history of chronic illness and medication, drug therapy (especially corticosteroids, anti hypertensive, anti coagulant, anti diabetic, anti convulsant medications), drug sensitivity and past anesthetic experience along with routine
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Anilkumar, P., Hussain Sait A. Mohamed, Shah M. Anzer, and D. Sreenivasan. "Intravenous Regional Anaesthesia for Upper Limb Surgeries: A Retrospective Study." International Journal of Current Pharmaceutical Review and Research 15, no. 11 (2023): 217–25. https://doi.org/10.5281/zenodo.11559887.

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AbstractBackground: In this study we wanted to evaluate Intravenous Regional Anaesthesia with regard toeffectiveness, usefulness, drugs and adjuvants used, types of surgeries done, safety and complications.Methods: This was a record based descriptive study conducted in Government Medical College, Ernakulam, fora period of 6 months among 129 patients, after obtaining IRC and IEC approval.Results: Lignocaine 0.5% along with muscle relaxants and either Dexmedetomidine or Buprenorphine orFentanyl or Morphine as adjuvants can be used for IVRA with high success rate.Conclusion: IVRA is a safe and ef
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Saroj, Kumar, Kumar Nirala Deepak, Kumari Ankita, and Prasad Sudama. "Comparison of the Effects of Epidural Levobupivacaine 0.5%, 20 Ml and Ropivacaine 0.75%, 20 Ml in Lower Limb Surgeries." International Journal of Pharmaceutical and Clinical Research 16, no. 6 (2024): 2380–83. https://doi.org/10.5281/zenodo.13621737.

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<strong>Background:</strong>&nbsp;Epidural anesthesia is a widely used technique for lower limb surgeries, providing effective pain control and facilitating faster recovery. Levobupivacaine and Ropivacaine are two commonly used local anesthetics for this purpose, each with distinct pharmacological profiles. While both agents offer benefits in terms of efficacy and safety, their comparative performance in clinical practice warrants further investigation.&nbsp;<strong>Aim:</strong>&nbsp;To compare the effects of epidural Levobupivacaine 0.5% and Ropivacaine 0.75% in patients undergoing lower lim
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Kanzariya, Tejas. "Abstract No.: ABS0617: Anaesthesia management of high risk cardiac patients for lower limb vascular surgeries." Indian Journal of Anaesthesia 66, Suppl 1 (2022): S49. http://dx.doi.org/10.4103/0019-5049.340690.

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Background and Aims: Managing Cardiac patients for noncardiac surgery is a daunting task. Haemodynamic disturbances during neuraxial blocks or general anesthesia may worsen the cardiac pathology. Peripheral nerve blocks can prove to be a better alternative in lower limb vascular surgeries. Methods: We included 25 high risk cardiac patients posted for lower limb vascular surgeries. Both lumbar plexus and sacral plexus blocks were performed. Haemodynamic monitoring and perioperative new cardiac events were recorded. Any additional supplementation of drugs was also noted. Results: Out of 25 patie
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Reddy, GPratapa, and G. Sarada. "Anesthetic profile of patients undergoing lower limb surgeries." MRIMS Journal of Health Sciences 4, no. 1 (2016): 60. http://dx.doi.org/10.4103/2321-7006.303070.

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Singh, Manpreet, Arvind Kumar Arya, Rajesh Singh Rautela, and Rajesh Bhardwaj. "Femorosciatic nerve block for lower limb orthopedic surgeries." Journal of Clinical Orthopaedics and Trauma 1, no. 1 (2010): 37–40. http://dx.doi.org/10.1016/s0976-5662(11)60008-8.

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Madhukant and Prasad Sudama. "Comparative Study to Evaluate the Clinical Efficacy and Safety of Isobaric Levobupivacaine vs. Hyperbaric Bupivacaine in lower Limb Orthopaedic Surgeries." International Journal of Pharmaceutical and Clinical Research 16, no. 5 (2024): 2819–22. https://doi.org/10.5281/zenodo.13823069.

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<strong>Background:</strong>&nbsp;Bupivacaine is a widely used local anesthetic in lower limb orthopaedic surgeries due to its long duration of action. However, its racemic mixture is associated with cardiotoxicity and central nervous system toxicity. Levobupivacaine, the S(&minus;)-enantiomer of bupivacaine, was developed to mitigate these risks while maintaining efficacy.&nbsp;<strong>Aim:</strong>&nbsp;This study aims to compare the clinical efficacy and safety of isobaric levobupivacaine versus hyperbaric bupivacaine in patients undergoing lower limb orthopaedic surgeries.&nbsp;<strong>Met
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Kavungal, Jyothish, Subramanian Vaidyanathan, Sameer Khateeb Mohammed, Ashwin Baby, and Afsal Rasheed. "Limb Salvage in Malignant Bone Tumours - A Prospective Follow-Up Study Conducted at Government Medical College, Thrissur from 2017 to 20." Journal of Evidence Based Medicine and Healthcare 8, no. 28 (2021): 2489–96. http://dx.doi.org/10.18410/jebmh/2021/461.

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BACKGROUND Limb salvage surgeries - Are they useful compared to amputation in bone tumours (malignant/recurrent). Starting from 1980s, bone tumour treatment has seen a revolution with the advent of limb salvage surgeries. From an era where amputation was the only option to the current day function preserving resections and complex reconstructions has been a major advance. The surgeon must ensure adequate resection of the involved bone and soft tissue so as to minimize chance of local recurrence. At no stage must adequate disease clearance be compromised in an attempt to achieve limb salvage. W
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Popsuishapka, Olexii, Valerii Lytvyshko, Olga Pidgaiska, Nataliya Ashukina, Kostiantyn Romanenko, and Zinaida Danуshchuk. "Reconstructive surgeries in the case of the knee joint osteoarthritis." ORTHOPAEDICS, TRAUMATOLOGY and PROSTHETICS, no. 3-4 (May 26, 2023): 29–38. http://dx.doi.org/10.15674/0030-598720223-429-38.

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Objective. To clarify the indications and volume of reconstructive surgeries under conditions of knee joint arthritis and to improve the methods of surgical correction of peri-articular deformations using an external rod fixator. Methods. During the last 10 years (2012‒2022), reconstructive surgeries were performed in 45 patients (49 joints). Indications for surgery were based on the study of pain and its localization, peri-articular deformation of the limb, ultrasound (USD) and X-ray examinations. Results. Indications for certain reconstructive surgical interventions on the knee joint are sub
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Kapshitar, A. V., and A. A. Kapshitar. "Sepsis as a cause of fatal cases after the lower limbs amputation at the hip level due to gangrene in patients with a diabetic foot syndrome." Modern medical technologies 41 part 1, no. 2 (2019): 29–35. http://dx.doi.org/10.34287/mmt.2(41).2019.6.

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Purpose of the study. To study frequency of fatal sepsis, the causes and severity of diabetes patients complicated by diabetic foot syndrome of the gangrene limb, after amputation of the lower limb at the hip level. Material and methods. Amputation of the lower limb at the hip level was performed in 180 patients with diabetic foot, gangrene of the limb. 15 (8,3%) died. Results. From the 15 patients who died, 9 died from sepsis. The age was 54–78 years old. On admission, sepsis was diagnosed in 5 and septic shock – in 4 patients. After examination and preparation, emergency surgeries were perfo
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Thapa, Shrawan Kumar, Manoj Kandel, Sunil Panta, and Bishwa Raj Adhikari. "Demography of Total Joint Replacement Surgeries Performed in a Tertiary Care Hospital: A Cross-sectional Survey." Journal of Nepal Medical Association 59, no. 243 (2021): 1161–65. http://dx.doi.org/10.31729/jnma.6949.

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Introduction: Total joint replacement of hip and knee is considered as one of the most successful orthopedic surgeries in the twenty-first century because of the only solution to end-stage arthritis of these joints. The real burden of the problem is yet to be established in developing countries like Nepal. This study aims to describe the demographic findings of the joint replacement surgeries among total lower limb surgeries in a tertiary care hospital. Methods: This cross-sectional survey was conducted using the hospital records of 73 total joint replacement surgeries of the lower limb in the
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Dr., Pujari Harika, and Sharada Dr. "A Comparative Study of Intrathecal Plain Bupivacaine Versus Bupivacaine with Midazolam for Subarachnoid Block in Lower Abdominal and Lower Limb Surgeries." International Journal of Innovative Science and Research Technology 8, no. 1 (2023): 2476–79. https://doi.org/10.5281/zenodo.7677980.

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A comparative study of intrathecal plain bupivacaine versus bupivacaine added with midazolam for subarachnoid block in lower limb surgeries and lower abdominal surgeries .  Methodology Patients were randomized as 30 patients each into two groups. Group &lsquo;B&rsquo; - received 3.5 ml of 0.5% hyperbaric bupivacaine + 0.4 ml of 0.9% saline intrathecally. Group &lsquo;BM&rsquo; - received 3.5 ml of 0.5%hyperbaric bupivacaine + 0.4 ml preservative free midazolam(5mg/ml) intrathecally.  Results The sensory blockade onset in group- BM was 165.76 sec and in group-B was 189.30 sec. The results wer
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Mortazavi, Mirmohammadtaghi, Mohammadreza Moharrami, Behrooz Nazari, and Hassan Mohammadipour Anvari. "Comparison of the Effects of Fluid Therapy With Normal Saline, Ringer, and Ringer’s Lactate During Anesthesia on the Hemodynamic Status and Events During Orthopedic Lower Limb Orthopedics Surgeries." Crescent Journal of Medical and Biological Sciences 10, no. 4 (2020): 176–81. http://dx.doi.org/10.34172/cjmb.2023.40.

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Objectives: Given that no study has so far carefully examined the effects and benefits of crystalloids on the hemodynamic status and events during the surgery for lower limb orthopedic surgeries, the current study aimed to compare fluid therapy with normal saline (NS), Ringer (R), and Ringer’s lactate (RL) during anesthesia on the hemodynamic status and events during lower limb elective orthopedic surgeries. Materials and Methods: This cross-sectional descriptive study was conducted in 2019 with the participation of 270 patients (three groups each including 90 subjects) who were scheduled for
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Pervej, Dr Abu Muhammad Abdullah, Dr Khaled Kaiser, Dr Mohammod Shajedur Rahman, et al. "Evaluating the Efficacy and Safety of a Multidrug Brachial Plexus Block Regimen Combining Lidocaine, Bupivacaine, and Dexamethasone for Major Upper Limb Surgeries in Bangladesh." SAS Journal of Surgery 11, no. 01 (2025): 37–42. https://doi.org/10.36347/sasjs.2025.v11i01.008.

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Background: Brachial plexus block is a widely used regional anesthesia technique for upper limb surgeries. Multidrug regimens incorporating lidocaine, bupivacaine, and dexamethasone aim to enhance block efficacy while maintaining safety. This study evaluates the comparative efficacy and safety of three brachial plexus block regimens using lidocaine, bupivacaine, and dexamethasone in patients undergoing upper limb surgeries. Methods: A retrospective cohort study was conducted involving 150 patients undergoing upper limb surgeries. Block efficacy was assessed through the onset and duration of se
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Adharsh, K., S. Daniel Arun, E. Pradeep, K. V. Arun Kumar, Haemanath Pandian, and Mohideen Sheik. "Role of Pregabalin in Pre-Operative and Post-Operative Pain Management of Lower Limb Orthopedic Surgeries." Journal of Orthopaedic Case Reports 14, no. 10 (2024): 263–69. http://dx.doi.org/10.13107/jocr.2024.v14.i10.4884.

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Introduction: Post-operative pain after orthopedic surgery has remained a challenging problem, which prolongs hospital stay and early rehabilitation. Pregabalin comes under the class of gabapentinoids that have been used in postoperative pain in arthroplasty and spine surgeries but studies regarding its role as pre-emptive analgesia in orthopedic limb surgeries are very few. Aims: To compare the efficacy of pre-operative pregabalin with a placebo drug in early post-operative pain management for lower limb orthopedics surgeries. Materials and Methods: A randomized double blinded prospective stu
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Sirga, Sudeep. "Comparative study between epidural bupivacaine with fentanyl versus ropivacaine with fentanyl combination for post operative analgesia in lower abdominal and lower limb surgeries." MedPulse International Journal of Anesthesiology 19, no. 3 (2021): 111–15. http://dx.doi.org/10.26611/101519313.

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Background: Adequate analgesia aids to restore normal functions including ventilation, coughing and mobility, thereby facilitating early rehabilitation and shortened hospital stay. Present study was aimed to compare epidural Bupivacaine with fentanyl versus ropivacaine with fentanyl combination for post operative analgesia in lower abdominal and lower limb surgeries at a tertiary hospital. Material and Methods: Present study was comparative, interventional study, conducted in patients aged 18–65 years, either gender, American Society of Anesthesiologists (ASA) physical status I–II, posted for
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Teichmüller, Karolin, Norman Rose, Johannes Dreiling, et al. "Incidence and treatment of complex regional pain syndrome after surgery: analysis of claims data from Germany." PAIN Reports 9, no. 6 (2024): e1210. http://dx.doi.org/10.1097/pr9.0000000000001210.

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Abstract Introduction: Complex regional pain syndrome (CRPS) is a rare complication after limb injuries. Early recognition of the symptomatology and interdisciplinary interventions are essential to prevent long-term disability and pain. Objective: This article presents results on the incidence of CRPS after surgery in Germany and treatments used by patients with CRPS, using claims data from the BARMER, a German nationwide health care insurance. Methods: A total of N = 85,862 BARMER patients with inpatient surgery on the upper or lower limb in 2018 were included. Patients with CRPS were identif
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International, Journal of Medical Science and Innovative Research (IJMSIR). "Comparison of Intrathecal Atropine versus Dexamethasone for Prevention of Nausea and Vomiting in Patients Undergoing Lower Limb Surgeries under Spinal Anaesthesia." International Journal of Medical Science and Innovative Research (IJMSIR) 10, no. 1 (2025): 132–39. https://doi.org/10.5281/zenodo.15259879.

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<strong>Abstract</strong> <strong>Background:</strong> For better pain management during lower limb surgeries, various adjuvants have been used intrathecally along with local anaesthetics. Spinal anesthesia is a widely used technique for lower limb surgeries, but it is often accompanied by side effects such as nausea and vomiting. Various pharmacological interventions have been explored to mitigate these side effects, including intrathecal atropine and dexamethasone. This study aims to compare the efficacy of intrathecal atropine and intrathecal dexamethasone in preventing nausea and vomiting
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DOMENE, Carlos Eduardo, Paula VOLPE, and Frederico A. HEITOR. "Robotic Roux-en-Y gastric bypass: operative results in 100 patients." ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 27, suppl 1 (2014): 9–12. http://dx.doi.org/10.1590/s0102-6720201400s100003.

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BACKGROUND: Laparoscopic gastric bypass is gold-standard for morbid obesity treatment. AIM: To describe the results of robotic gastric bypass for morbid obesity patients. METHOD: Were operated on 100 morbidly obese patients through totally robotic gastric bypass between 2013 and 2014. They were 83% female. The age ranged from 20 to 65 years old (medium 48,5 years); the body mass index varied between 38-67 (medium 42,3 kg/cm2). The procedure was designed with 3 cm long gastric pouch, 1 m biliopancreatic limb, 1,2 m alimentary limb, manual or stapled anastomosis. There were four super-super-obes
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Pramana, I. Made Dwi, and Adinda Putra Pradhana. "Supraclavicular Brachial Plexus Block Guided by Ultrasonography in Pediatric Patient: A Case Report." Bioscientia Medicina : Journal of Biomedicine and Translational Research 7, no. 12 (2023): 3827–31. http://dx.doi.org/10.37275/bsm.v7i12.898.

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Background: Supraclavicular brachial plexus block has proven to be very useful in upper limb surgeries in pediatric patients. Supraclavicular brachial plexus block is preferred over general anesthesia for pediatric patients undergoing upper limb surgeries. This study aimed to report a procedure of supraclavicular brachial plexus block guided by ultrasonography in a pediatric patient undergoing orthopedic surgery on the upper extremity, which yielded good results, a high success rate, reduced opioid usage, and aided in faster recovery while minimizing complications.&#x0D; Case presentation: The
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Savov, Peter, Lars-Rene Tuecking, Henning Windhagen, and Max Ettinger. "Individual Revision Knee Arthroplasty Is a Safe Limb Salvage Procedure." Journal of Personalized Medicine 11, no. 6 (2021): 572. http://dx.doi.org/10.3390/jpm11060572.

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Introduction: Revision total knee arthroplasty after multiple pre-surgeries is challenging. Due to severe bone defects, standard implants for metaphyseal and diaphyseal anchoring may no longer be suitable. The primary aim of this case series is to evaluate the early complication rate for individual knee implants with custom-made cones and stems after two-stage revision with severe bone defects. Methods: Ten patients who were treated with custom-made 3D-printed knee revision implants were included. Inclusion criteria were a two-stage revision due to late-onset or chronic periprosthetic joint in
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Zak, Lukas, Thomas Manfred Tiefenboeck, and Gerald Eliot Wozasek. "Intramedullary Bone Lengthening Following Preceding Hip Surgery—A Case Series." Journal of Clinical Medicine 9, no. 12 (2020): 4104. http://dx.doi.org/10.3390/jcm9124104.

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Limb length discrepancy (LLD) is a common problem after joint-preserving hip surgeries, hip dysplasia, and hip deformities. Limping, pain, sciatica, paresthesia, and hip instability are common clinical findings and may necessitate limb-lengthening procedures. The study included five patients (two female and three male, mean age of 28 years (20–49; SD: 12)) with symptomatic limb length discrepancy greater than 2.5 cm (mean: 3.6 cm) after total hip arthroplasty (THA), hip dysplasia, or post-traumatic hip surgery. They underwent either ipsi- or contralateral intramedullary limb-lengthening surger
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Lam, Aaron, Shawn S. Richardson, Josh Buksbaum, et al. "Chronic Osteomyelitis of the tibia and ankle treated with Limb Salvage Reconstruction." Journal of Bone and Joint Infection 4, no. 6 (2019): 306–13. http://dx.doi.org/10.7150/jbji.40337.

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Abstract. Introduction: To confirm the success of our limb salvage treatment protocol and determine what factors are predictive of success versus failure in limb salvage techniques for patients with chronic osteomyelitis of the tibia and ankle.Methods: Retrospective case series analyzing factors and outcomes in patients who underwent limb salvage techniques for chronic osteomyelitis of tibia or ankle. Main outcome measurements included infection controlled without the need for amputation or chronic antibiotic suppression and union of infected non-unions.Results: Mean follow-up was 3.9 years. O
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Gupta, Richa, Anjali Aggarwal, Tulika Gupta, Harjeet Kaur, Sunil Gaba, and Daisy Sahni. "Superficial upper limb vasculature and its surgical implications." Indian Journal of Plastic Surgery 49, no. 02 (2016): 258–60. http://dx.doi.org/10.4103/0970-0358.191314.

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ABSTRACTAny kind of anatomical variation whether encountered during cadaveric dissections or routine clinical or surgical procedures needs to be reported and taken into account. This can be quite helpful in planning surgeries accordingly and avoid disastrous complications. During routine cadaveric dissection, authors found a superficial course of arteries of the arm as well as the forearm, unilaterally in one cadaver. In this case, there were two brachial arteries - superficial and deep. Superficial brachial artery terminated into superficial radial and superficial ulnar artery. Deep brachial
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Ashok Thudukuchi Ramanathan and Kevin lourdes. "Imaging in Fracture surgeries - a tool for quality assessment." International Journal of Research in Pharmaceutical Sciences 11, no. 2 (2020): 1679–83. http://dx.doi.org/10.26452/ijrps.v11i2.2056.

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Radiation in orthopaedic surgeries was considered to be commonly hazardous, but also can be used as tool to improvise the surgical skills, limitations of exposure, risk analysis and making of alternate arrangements whenever required. We aim to analyse the number of times of imaging taken intra-operatively with C-arm for all acute closed lower limb fractures, which are all electively planned for intramedullary nailing fixation. It was a single centre, prospective randomized control double blind study, acute closed single plane fracture of lower limb like tibia shaft fracture, femur shaft fractu
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Jain, Shray, S. Jain, S. Gupta, and R. K. Kanojia. "Estimation of adequate tourniquet pressure for paediatric limb surgeries." Journal of Clinical Orthopaedics and Trauma 57 (October 2024): 102597. http://dx.doi.org/10.1016/j.jcot.2024.102597.

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Harmandeep, Kaur, Singh Amrinder, and Kumar Sanjeev. "Comparison of Dexmedetomine vs Clonidine When Added to Hyperbaric Ropivacaine (0.5%) for Lower Limb Orthopaedic Surgeries under Subarachnoid Block." International Journal of Pharmaceutical and Clinical Research 16, no. 2 (2024): 1707–11. https://doi.org/10.5281/zenodo.11086525.

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<strong>Background:</strong>&nbsp;The use of adjuvants in spinal anesthesia to improve analgesia has been extensively researched. Dexmedetomidine and clonidine, both alpha-2 adrenergic agonists, are commonly used adjuvants. The aim of the study was to compare the efficacy and safety of dexmedetomidine versus clonidine as adjuvants to hyperbaric ropivacaine in lower limb orthopaedic surgeries conducted under subarachnoid block.&nbsp;<strong>Methods:</strong>&nbsp;The study was conducted in which 80 individuals undergoing lower limb surgeries under subarachnoid block. Patients were equally alloc
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Wu, Tong, and Yong Ye. "The Effect of Lower-Limb Exercise on Pain Management of the Patients Undergoing Posterior Lumbar Fusion Surgery: A Retrospective Case-Control Study." Pain Research and Management 2021 (December 3, 2021): 1–6. http://dx.doi.org/10.1155/2021/3716696.

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Purpose. The purpose of this study is to investigate the clinical effect of lower-limb exercise, when combined with celecoxib, on pain management of patients undergoing posterior lumbar fusion surgeries. Methods. The patients undergoing posterior lumbar fusion surgeries between 01/2018 and 06/2021 were retrospectively identified, with their data collected. After surgery, some patients took celecoxib for analgesia (celecoxib group, 200 mg/day) while the others took celecoxib together with lower-limb exercise (combined group, celecoxib-200 mg/day). On postoperative days (POD) 1, 3, 7, and 14, da
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International, Journal of Medical Science and Advanced Clinical Research (IJMACR). "Comparison of Dexamethasone and Magnesium Sulphate As Adjuvants To 0.5% Ropivacaine in Ultrasound Guided Supraclavicular Brachial Plexus Block- A Prospective, Randomized, Double Blind Study." International Journal of Medical Science and Advanced Clinical Research (IJMACR) 8, no. 1 (2025): 88–92. https://doi.org/10.5281/zenodo.15234111.

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<strong>Abstract</strong> <strong>Introduction</strong> Peripheral nerve blocks (PNB) are preferred over general anesthesia in upper limb surgeries. Regional nerve blocks work on the principle of blocking conduction of painful stimulus along the pathway of nerve fibres in the region. Ultrasound has made the technique of giving the block easier. Brachial plexus block is the most preferred PNB for upper limb surgeries and supraclavicular approach is used for surgeries for elbow, forearm and hand. Ropivacaine, a long acting S-enantiomer of Bupivacaine, has better sensorimotor differentiation and
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Ahmed, Md Moqueeth, Khaliq Ahmed Md, Mrunalini Alugolu, and J. Naresh Kumar. "Enhancing Spinal Anesthesia for Lower Limb Surgeries: A Comparative Study of Intrathecal Midazolam and Hyperbaric Bupivacaine." Journal of Neonatal Surgery 14, no. 8S (2025): 6–10. https://doi.org/10.52783/jns.v14.2487.

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Background: Spinal anesthesia is a critical technique for lower limb surgeries, offering rapid onset and reliability. However, the limited duration of anesthesia and postoperative analgesia with bupivacaine presents a clinical challenge. This study investigates the efficacy of adding preservative-free midazolam to hyperbaric bupivacaine to enhance the analgesic profile of spinal anesthesia. Methods: This prospective, randomized, single-blinded study involved 60 patients undergoing elective lower limb surgeries, divided into two groups. Group B received 3 ml of 0.5% hyperbaric bupivacaine, and
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Horsch, Axel, Svenja Gleichauf, Burkhard Lehner, et al. "Lower-Limb Amputation in Children and Adolescents—A Rare Encounter with Unique and Special Challenges." Children 9, no. 7 (2022): 1004. http://dx.doi.org/10.3390/children9071004.

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Background/Aim: The pattern of lower-limb amputation, indications, complications, and revision in pediatric cases differs globally. Therefore, we conducted this study to describe the patterns of lower-limb amputation at our institution. Methods: During a set period between 2010 and 2020, adolescent patients undergoing lower-limb amputation within the orthopedic department of Heidelberg University Hospital were retrospectively collected and analyzed. The retrieved dataset included two parts: data on lower-limb amputations and data on subsequent complications and revision surgeries at the same t
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Solanki, MD, PDCC, MAMS, Sohan Lal, Raghu S. Thota, MD, MAMS, Jeson Rajan Doctor, MD, DNB, MNAMS, et al. "Multimodal opioid sparing onco-anesthesia: A consensus practice guideline from Society of Onco-Anesthesia and Perioperative Care (SOAPC)." Journal of Opioid Management 17, no. 5 (2021): 417–37. http://dx.doi.org/10.5055/jom.2021.0675.

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Opioids are an indispensable part of perioperative pain management of cancer surgeries. Opioids do have some side effects and abuse potential, and some laboratory data suggest a possible association of cancer recurrence with perioperative opioid use. Opioid-free anesthesia and opioid-sparing anesthesia are emerging new concepts worldwide to safeguard patients from adverse effects of opioids and potential abuse. Opioid-free anesthesia could lead to ineffective pain management, leaving the perioperative physician with limited options, while opioid-sparing anesthesia may be a rational approach. T
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Afaan Zahoor, Qazi, Arshi Taj, and Sana Khan. "SAFETY AND EFFICACY OF ISOBARIC ROPIVACAINE FOR SPINAL ANESTHESIA IN CARDIAC PATIENTS UNDERGOING LOWER LIMB SURGERIES: A PROSPECTIVE STUDY." International Journal of Advanced Research 13, no. 01 (2025): 751–57. https://doi.org/10.21474/ijar01/20254.

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Background:Patients with pre-existing cardiac conditions undergoing lower limb surgeries face significant anesthetic risks. General anesthesia, often used in these surgeries, may exacerbate cardiovascular instability by increasing myocardial oxygen demand, blood pressure, and heart rate. Additionally, certain anesthetic agents can depress myocardial function, increasing the risk of arrhythmias, particularly in cardiac patients. Regional anesthesia, especially spinal anesthesia, provides an alternative by reducing sympathetic nervous system activity and maintaining or improving hemodynamic stab
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Kimura, Hiroaki, Hiroyuki Tsuchiya, Toshiharu Shirai, et al. "SUCCESSFUL MANAGEMENT OF INTRACTABLE INFECTION AFTER LIMB-SAVING SURGERY: A CASE REPORT." Journal of Musculoskeletal Research 11, no. 04 (2008): 191–98. http://dx.doi.org/10.1142/s0218957708002103.

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Infections following limb-saving surgeries still happen frequently and are refractory to treatment, even though the treatment of massive bone defects caused by bone resection of bone tumors has improved gradually. Once infections become intractable, they generally result in amputations in spite of all kinds of treatment. We report the case of a patient who developed an intractable infection after limb-saving surgery utilizing a massive frozen autograft and a tumor prosthesis, but whose limb was finally successfully salvaged by multiple surgical interventions. We conclude that continued perseve
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Saxena, Dipti, Sadhana Sanwatsarkar, Atul Dixit, and Bipin Arya. "Comparative study of duration of analgesia with epidural bupivacaine and bupivacaine with tramadol in lower limb surgeries." International Journal of Research in Medical Sciences 5, no. 5 (2017): 2003. http://dx.doi.org/10.18203/2320-6012.ijrms20171833.

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Background: The administration of local anaesthetic and opioid mixture via epidural route is excellent for post-operative pain during lower limb surgeries. This combination provides better quality of analgesia, lower side effects and high level of patient satisfaction. Therefore, this study was taken up to evaluate the efficacy safety, tolerance and side effects for the combination of tramadol and bupivacaine in the management of post-operative pain.Methods: This was a prospective study where a total of 40 patients; 20 each in group I and II were selected. Patients who were admitted for lower
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