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Journal articles on the topic 'Load cell'

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1

Gongora-Rubio, Mário R., M. Roberti, Z. M. da Rocha, and L. Fraigi. "LTCC Post Load Cell." Journal of Microelectronics and Electronic Packaging 3, no. 4 (October 1, 2006): 169–76. http://dx.doi.org/10.4071/1551-4897-3.4.169.

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This paper presents the development of a force post compressive load cell, fabricated using Low Temperature Cofired Ceramics (LTCC) technology. It was implemented as an LTCC mechanical load cell structure with a z-axis thick film strain gage using two different approaches. Fabrication methods and materials are explored in this work and fabricated devices are presented. This paper will also present the results of initial electromechanical sensitivity to load force and temperature tests. Compressive force behavior is consistent, in a strain level up to 1.500 micro-strain.
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2

Bowen, Anthony. "Load Cell Applications Offshore." Measurement and Control 38, no. 6 (July 2005): 175–78. http://dx.doi.org/10.1177/002029400503800602.

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3

Pratama, Bobby Noval. "Effect of Load Cell Load Calibration on Electric Wheelchair." Brilliance: Research of Artificial Intelligence 2, no. 3 (June 13, 2022): 77–80. http://dx.doi.org/10.47709/brilliance.v2i3.1547.

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A wheelchair is an assistive device for patients who are seriously injured or ill. Especially for people with disabilities or people who can't walk using their feet. For patients who experience total paralysis such as pain in the nerves to move the wheelchair, someone needs to push the wheelchair. If there is no one around the patient, the patient has difficulty moving the wheelchair using his hands and feet to change positions. In this research, an electric wheelchair has been created using a load cell control with body position as the driving output. Based on the test results, if the body leans forward then the wheelchair moves forward, if the body leans back then the wheelchair moves backwards, If the body leans to the left then the wheelchair moves to the left and if the body leans to the right then the wheelchair moves to the right. This study aims to analyze the ability of the load cell as the propulsion output of the electric wheelchair to the user's weight. In the results of the study, it can be seen that body weight can have a greater effect if the user's mass is getting heavier.
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4

Osman, Seifelnasr Mahmoud, Rolf Kumme, Hany Mohamed El-Hakeem, Frank Loeffler, Ebtisam Hsan Hasan, Ragaie Mohamed Rashad, and Fawzaia Hanem Kouta. "Multi-capacity load cell prototype." ACTA IMEKO 5, no. 3 (November 4, 2016): 64. http://dx.doi.org/10.21014/acta_imeko.v5i3.310.

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<p class="Abstract"><span>This article illustrates an advanced approach in force measurement standards. It gives a spot on the design, manufacturing and evaluation for a prototype of force transducer with multi-capacity. This prototype has three adjustable capacities (5kN, 10kN and 15kN) and works on compression mode. The introduced design offers a comparative load cell looking forward to replace three force transducers with the same capacities (5kN, 10kN and 15kN) which are commercially available. Experimental results reveal satisfactory agreements with that calculated with analytical method and results simulated using finite element techniques. The detailed metrological characteristics of this multi-capacity load cell will be published later.</span></p>
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5

Vallascas, Rinaldo, and Gian Franco Porcu. "Directional load‐cell anemometric probe." Review of Scientific Instruments 60, no. 8 (August 1989): 2740–44. http://dx.doi.org/10.1063/1.1140651.

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6

Nielsen, H. A. "THE TEN DOLLAR LOAD CELL." Experimental Techniques 12, no. 2 (February 1988): 21–24. http://dx.doi.org/10.1111/j.1747-1567.1988.tb02101.x.

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7

NAKANO, Osamu, Norimitsu KISHI, Ken-ichi G. MATSUOKA, and Yukio GOTO. "Trial manufacture of load cell for measurement of impact load." Doboku Gakkai Ronbunshu, no. 453 (1992): 155–61. http://dx.doi.org/10.2208/jscej.1992.453_155.

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8

Fernandez, Rajan. "Multi-Axis Load Cell Designs Employing Multiple Shear Beams." Applied Mechanics and Materials 226-228 (November 2012): 1981–86. http://dx.doi.org/10.4028/www.scientific.net/amm.226-228.1981.

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Binocular and parallel plate structure load cells are very successful designs for strain based measurements of shear loads. In this paper we use finite element methods (FEM) to investigate the suitability of these two load cell designs for use in a force plate and compare the sensitivity of these two force plates to that of the Heglund’s force plate. Each force plate is also sensitive to two moments with axis in the same plane as the force plate. If the force plate is to be used as a two component force-moment sensor, we determine which moment axis is best to use. Finally, a novel six-axis load cell is modelled by assembling three force plates together with rotational symmetry. The sensitivity of the six-axis load cell is calculated using FEM. Analysis of the six axis load cell predicts good measurement sensitivity and isotropy while maintaining low interference between measurement axes. Further benefits of the load cell design are discussed.
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9

Atawi, Ibrahem E., Ahmed M. Kassem, and Sherif A. Zaid. "Modeling, Management, and Control of an Autonomous Wind/Fuel Cell Micro-Grid System." Processes 7, no. 2 (February 8, 2019): 85. http://dx.doi.org/10.3390/pr7020085.

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This paper proposes a microelectric power grid that includes wind and fuel cell power generation units, as well as a water electrolyzer for producing hydrogen gas. The grid is loaded by an induction motor (IM) as a dynamic load and constant impedance load. An optimal control algorithm using the Mine Blast Algorithm (MBA) is designed to improve the performance of the proposed renewable energy system. Normally, wind power is adapted to feed the loads at normal circumstances. Nevertheless, the fuel cell compensates extra load power demand. An optimal controller is applied to regulate the load voltage and frequency of the main power inverter. Also, optimal vector control is applied to the IM speed control. The response of the microgrid with the proposed optimal control is obtained under step variation in wind speed, load impedance, IM rotor speed, and motor mechanical load torque. The simulation results indicate that the proposed renewable generation system supplies the system loads perfectly and keeps up the desired load demand. Furthermore, the IM speed performance is acceptable under turbulent wind speed.
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10

AliAl-Juboori, Firas, and Namariq Sami AL-Dahwi. "Load Balancing Algorithm based Adaptive Handovers and Target Cell Load Estimation." International Journal of Computer Applications 84, no. 17 (December 18, 2013): 22–25. http://dx.doi.org/10.5120/14679-2053.

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11

Jeon, Byeong Ha, Dong Seop Han, and Kwon-Hee Lee. "Development of Load-Cell-Based Anemovane." Transactions of the Korean Society of Mechanical Engineers A 37, no. 5 (May 1, 2013): 685–91. http://dx.doi.org/10.3795/ksme-a.2013.37.5.685.

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12

Mindel, Gerard S. "Load and dispersion cell for sound." Journal of the Acoustical Society of America 88, no. 6 (December 1990): 2919. http://dx.doi.org/10.1121/1.399574.

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13

White, N. M., and J. E. Brignell. "A planar thick-film load cell." Sensors and Actuators A: Physical 26, no. 1-3 (March 1991): 313–19. http://dx.doi.org/10.1016/0924-4247(91)87010-z.

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14

Kimura, Shuuichi, Tatsuro Nanba, Shigeo Honma, and Hiroshi Kondo. "651 The measured value of dynamic load cell is proportional to the size of load cell." Proceedings of the Dynamics & Design Conference 2010 (2010): _651–1_—_651–5_. http://dx.doi.org/10.1299/jsmedmc.2010._651-1_.

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15

Capobianco, G., N. Bohun, M. Gratton, R. Serra, A. Zinbi, and N. Rigollet. "Both radial and axial load distribution measurement on a V-band clamp by a new load cell design." Insight - Non-Destructive Testing and Condition Monitoring 64, no. 8 (August 1, 2022): 432–36. http://dx.doi.org/10.1784/insi.2022.64.8.432.

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This paper presents a method for determining the axial and radial load distribution of the moment generated in a V-band clamp and is validated experimentally using finite element analysis (FEA). The method comprises a slotted flange, which is distinguished by having three different profiles for different levels of load symmetrically divided among eight sectors. Each sector is characterised and calibrated. The load cell is analysed using finite element Abaqus software to predict and corroborate the system. In the experimental test, the axial and radial loads are measured using strain gauges for each sector and the total axial load is validated by three button sensors. Tests on the V-band clamp were successfully carried out and indicated a non-uniform distribution of axial and radial loads, with three highlights relating to existing papers: improved results for axial loads, new results for radial loads and an analysis of the moment and its direction, which is consistent with finite element studies.
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16

Wiegerink, Remco, Robert Zwijze, Gijs Krijnen, Theo Lammerink, and Miko Elwenspoek. "Quasi-monolithic silicon load cell for loads up to 1000 kg with insensitivity to non-homogeneous load distributions." Sensors and Actuators A: Physical 80, no. 2 (March 2000): 189–96. http://dx.doi.org/10.1016/s0924-4247(99)00265-4.

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17

Yamada, Hiroyuki, Kohei Tateyama, Nagahisa Ogasawara, and Keiko Watanabe. "Dynamic Compressive Behaviour of Closed-Cell Foam Materials Using Load-Measuring Apparatus with Opposite Load-Cells." EPJ Web of Conferences 183 (2018): 02031. http://dx.doi.org/10.1051/epjconf/201818302031.

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It is necessary to evaluate the mechanical properties of foam materials at wide range of strain rates, since these materials have the strain rate dependence of strength. In this study, we evaluated the dynamic compressive behaviour of the closed-cell foam materials using the load-measuring apparatus with opposite load-cells, which is applying the drop-weight testing machine. In order to measure large deformation at dynamic strain rate range, universal rate range load-cell, which can reduce the influence of the reflected stress wave, was used. In addition, load equilibrium can evaluate using opposite load-cells which consist of movable (drop-weight) and stationary load-cells. In this study, the commercially available ALPORAS closed-cell aluminum foam was used. From the results of quasi-static tests, three deformation processes of elastic response, plateau deformation and densification were confirmed in stress-strain relation. Within the set of experiments, the closed-cell aluminum foam was locally deformed from cells with low strength and the stress variation occurred during plateau deformation, regardless of the strain rate. In addition, it was clarified that the stress equilibrium was not achieved at the dynamic strain rate. This is thought to be a phenomenon caused by local deformation of cell structure.
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18

KOJIMA, Yukio. "Load position error due to dimensional error in beam type load cell." Transactions of the Japan Society of Mechanical Engineers Series C 52, no. 483 (1986): 2869–74. http://dx.doi.org/10.1299/kikaic.52.2869.

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19

Pradhan, Sanjaya K., Sudip K. Mazumder, Joseph Hartvigsen, and Michele Hollist. "Effects of Electrical Feedbacks on Planar Solid Oxide Fuel Cell." Journal of Fuel Cell Science and Technology 4, no. 2 (July 17, 2006): 154–66. http://dx.doi.org/10.1115/1.2713773.

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Planar-solid-oxide-fuel-cell stacks (PSOFCSs), in PSOFC-based power-conditioning systems (PCSs), are subjected to electrical feedbacks due to the switching power electronics and the application loads. These feedbacks (including load transient, current ripple due to load power factor and inverter operation, and load harmonic distortion) affect the electrochemistry and the thermal properties of the planar cells thereby potentially deteriorating the performance and reliability of the cells. In this paper, a detailed study on the impact of these electrical effects on the performance of the PSFOC is conducted. To analyze the impact of such feedbacks, a spatiotemporal numerical system model is developed on a low-cost Simulink modeling platform and the model under transient and steady-state conditions is validated experimentally. Using this validated model, parametric analyses on the impacts of transience, power factor, and distortion of the application load as well as low-frequency current ripple is conducted. Finally, using experimental data, we demonstrate the long-term impact of two most significant electrical feedbacks on the area-specific resistance and the corresponding loss of effective stack power.
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20

Manaseer, Saher, Ahmad Alamoush, and Osama Rababah. "Load Balancing for Hex-Cell Interconnection Network." International Journal of Communications, Network and System Sciences 09, no. 04 (2016): 98–116. http://dx.doi.org/10.4236/ijcns.2016.94009.

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21

Vega Gómez, Leonardo César, Sonnia Pavoni Oliver, Dilaila Criado Cruz, and Víctor Eugenio Escartín Fernández. "Virtual Instrumentation for load cell signal processing." Visión electrónica 14, no. 2 (December 31, 2020): 222–27. http://dx.doi.org/10.14483/22484728.17428.

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In different spheres of everyday life it is very important to determine the weight of substances, objects and peoples. Strain gauges are widely used in load cells for electronic scales. However, the signal from these transducers presents noise due to various factors. This work presents a virtual instrument developed in LabVIEW for acquisition and processing of the AC108B/BW load cell signal. A moving average digital filter was developed, in order to decrease the amplitude of the signal noise.
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22

Hong, Young-Dae, and Bumjoo Lee. "Logarithmic Strain Model for Nonlinear Load Cell." Sensors 19, no. 16 (August 9, 2019): 3486. http://dx.doi.org/10.3390/s19163486.

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General load cells have typically constant sensitivity throughout the measurement range, which is acceptable for common force measurement systems. However, it is not adequate for high-performance control and high-stroke applications such as robotic systems. It is required to have a higher sensitivity in a small force range than that in a large force range. In contrast, for large loading force, it is more important to increase the measurement range than the sensitivity. To cope with these characteristics, the strain curve versus the force measurement should be derived as a logarithmic graph. To implement this nonlinear nature, the proposed load cell is composed of two mechanical components: an activator, which has a curved surface profile to translocate the contact point, and a linear torque measurement unit with a moment lever to measure the loading force. To approximate the logarithmic deformation, the curvature of the activator was designed by an exponential function. Subsequent design parameters were optimized by an evolutionary computation.
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23

Rumbara, Robby Debriand. "RANCANG BANGUN TIMBANGAN LOAD CELL TIPE S." Metal Indonesia 40, no. 1 (June 30, 2018): 34. http://dx.doi.org/10.32423/jmi.2018.v40.34-40.

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Timbangan dirancang dengan men-scale down dari timbangan kapasitas yang lebih besar. Tipe Load Cell ditentukan dan beban serta sensitivitas dihitung. Load Cell tipe S dimodelkan dengan perangkat lunak. Load Cell tipe S dimanufaktur dengan mesin CNC dan dibuat rangkaian elektronik. Pengukuran dilakukan pada dua titik: tanpa penguat dan dengan penguat. Pengukuran menghasilakan grafik dengan persamaan y = 0.0003x + 0.0031 (tanpa penguat) dan y = 0.061x + 0.191 (dengan penguat). Berat minimal yang dapat diukur oleh timbangan sekitar 1000~30.000 kg.
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24

RUAN, Liqun, Hirooki TATUTA, Kensiro FUKUTA, Yasuo MARUMO, and Yasuhiro IMAMURA. "G030121 Development of three-dimension load cell." Proceedings of Mechanical Engineering Congress, Japan 2011 (2011): _G030121–1—_G030121–3. http://dx.doi.org/10.1299/jsmemecj.2011._g030121-1.

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25

KOJIMA, yukio. "Nonlinear Characteristics of Beam Type Load Cell." Transactions of the Japan Society of Mechanical Engineers Series C 57, no. 540 (1991): 2764–69. http://dx.doi.org/10.1299/kikaic.57.2764.

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26

KOJIMA, Yukio, Michito UTSUNOMIYA, and Seiji NISHIDE. "Transient temperature responses of beam load cell." Transactions of the Japan Society of Mechanical Engineers Series A 51, no. 461 (1985): 273–76. http://dx.doi.org/10.1299/kikaia.51.273.

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27

Robinson, G. M. "Finite element modelling of load cell hysteresis." Measurement 20, no. 2 (February 1997): 103–7. http://dx.doi.org/10.1016/s0263-2241(97)00021-3.

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28

SAITOH, Tsuyoshi, Kazuyosi NISHIHRA, and Ichiro KITAYAMA. "Development of a small pylon load cell." Proceedings of Conference of Kansai Branch 2003.78 (2003): _6–29_—_6–30_. http://dx.doi.org/10.1299/jsmekansai.2003.78._6-29_.

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29

Shi, W. J., N. M. White, and J. E. Brignell. "Adaptive filters in load cell response correction." Sensors and Actuators A: Physical 37-38 (June 1993): 280–85. http://dx.doi.org/10.1016/0924-4247(93)80047-k.

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30

Hurschler, C., R. McCabe, and R. Vanderby. "A SMALL STRAIN GAGE BASED LOAD CELL." Experimental Techniques 19, no. 3 (May 1995): 13–15. http://dx.doi.org/10.1111/j.1747-1567.1995.tb00852.x.

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31

Palmqvist, Jan, Matz Lenner, and Stig-Inge Gustafsson. "Cutter head forces and load cell scanning." Wood Science and Technology 37, no. 3-4 (December 1, 2003): 199–211. http://dx.doi.org/10.1007/s00226-003-0174-8.

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32

Dixon, Michael J. "Development of a load-cell compensation system." Experimental Mechanics 31, no. 1 (March 1991): 21–24. http://dx.doi.org/10.1007/bf02325718.

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33

Huo, Haibo, Haidong Yang, Kui Xu, Xinghong Kuang, and Jingxiang Xu. "Survey on H∞ Robust Control of the Solid Oxide Fuel Cell." Mathematical Problems in Engineering 2021 (March 18, 2021): 1–10. http://dx.doi.org/10.1155/2021/6693971.

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Excessive use of fuel or being underutilized will make the actual performance of solid oxide fuel cells (SOFCs) affected by a lot, and at the same time, in order to meet the demands of DC load voltage, a controller of the SOFC that is subjected to small varying loads is proposed on the basis of H∞ control theory. For the controller design, a state-space representation of the SOFC by using small-signal linearization is derived. To evaluate the control performance, the presented H∞ controller is tested on the SOFC stack with various load disturbances. The results show that the obtained H∞ controller can mitigate the voltage oscillations and deviations and can keep fuel utilization constant at varying loads.
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34

Davis, Mark W., A. Hunter Fanney, Michael J. LaBarre, Kenneth R. Henderson, and Brian P. Dougherty. "Parameters Affecting the Performance of a Residential-Scale Stationary Fuel Cell System." Journal of Fuel Cell Science and Technology 4, no. 2 (May 8, 2006): 109–15. http://dx.doi.org/10.1115/1.2713767.

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Researchers at the National Institute of Standards and Technology have measured the performance of a residential fuel cell system when subjected to various environmental and load conditions. The system, which uses natural gas as its source fuel, is capable of generating electrical power at three nominal power levels (2.5, 4.0, and 5.0kW) while providing thermal energy for user-supplied loads. Testing was conducted to determine the influence of ambient temperature, relative humidity, electrical load, and thermal load on system performance. Steady-state and transient tests were conducted. The steady-state tests were performed in accordance with the American Society of Mechanical Engineering Fuel Cell Power Systems Performance Test Code (PTC-50) for fuel cell power systems. The results of the investigation are being used to develop a proposed rating procedure for residential fuel cell units.
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35

Kim, Tae-Hyeong, and Dong-Seop Han. "Comparison of Load Ratio of Load-cell type Anemometer with Windswept Shape Variation." Journal of Korean navigation and port research 36, no. 10 (December 31, 2012): 839–44. http://dx.doi.org/10.5394/kinpr.2012.36.10.839.

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36

Auld, Allie E., Keyue M. Smedley, Fabian Mueller, Jack Brouwer, and G. Scott Samuelsen. "Load-following active power filter for a solid oxide fuel cell supported load." Journal of Power Sources 195, no. 7 (April 2, 2010): 1905–13. http://dx.doi.org/10.1016/j.jpowsour.2009.10.005.

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37

Demetropoulos, Constantine K., Craig R. Morgan, Dilip K. Sengupta, and Harry N. Herkowitz. "Development of a 4-axis load cell used for lumbar interbody load measurements." Medical Engineering & Physics 31, no. 7 (September 2009): 846–51. http://dx.doi.org/10.1016/j.medengphy.2009.04.002.

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38

Chatterjee, Karunamoy, Sankar Narayan Mahato, and Subrata Chattopadhyay. "Weighing System by Load Cell Response Rectification Method." International Journal of Measurement Technologies and Instrumentation Engineering 2, no. 3 (July 2012): 34–44. http://dx.doi.org/10.4018/ijmtie.2012070104.

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In the area of mass production, the products are weighted using load cell based weighting system. A load cell may be capacitive or resistive, is an uncontrollable weighing device. Load cell response rectification can be used to speed up the process of measurement. This paper investigates the application of analog adaptive techniques in load cell response rectification and modeling of an accurate weighing system by using that load cell. The load cell is a sensor with an oscillatory output in which the measurand contributes to response parameters. Thus, a compensation filter needs to track variation in measurand whereas a simple, fixed filter is only valid at one load value. To facilitate this investigation, computer models for the load cell and the adaptive compensation filter have been developed and implemented in PSpice. Simulation results are presented demonstrating the effectiveness of the proposed compensation technique.
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39

Miyagi, Y., S. Kobayashi, J. Nishimura, M. Fukui, and H. Kanaide. "Resting load regulates vascular sensitivity by a cytosolic Ca(2+)-insensitive mechanism." American Journal of Physiology-Cell Physiology 268, no. 6 (June 1, 1995): C1332—C1341. http://dx.doi.org/10.1152/ajpcell.1995.268.6.c1332.

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The cellular mechanism underlying the regulation of the contraction of vascular smooth muscles by resting load is unknown. To determine the effects of changes in the resting load on vascular sensitivity to high K+ and to 9,11-dideoxy-11 alpha, 9 alpha-epoxy-methanoprostaglandin F2 alpha (U-46619), the force and cytosolic calcium concentration ([Ca2+]i) of arterial strips were recorded at resting loads of 200 (optimal load), 50, and 10 mg. A decrease in the resting load elicited a small decrease in the basal [Ca2+]i level without affecting the extent of maximal [Ca2+]i elevation induced by either stimulus. Through a decrease in the resting load, the concentration-response curves for the force development of high K+ or of U-46619 shifted to the right, whereas those for [Ca2+]i did not. We conclude that the basal [Ca2+]i level and the force development, but not the agonist-induced [Ca2+]i signals, of vascular smooth muscles depend on the resting load. We response that the resting load regulates the sensitivity of vascular smooth muscles, irrespective of types of stimuli, through a [Ca2+]i-insensitive mechanism.
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40

Lee, Ling Chun, Yu Yawn Chen, Jasson Chiang, Li Chun Chang, and Kuen Chang Hsieh. "The Design of Dual-Axis Load Cell for Measuring Force Load in Kayak Paddling." Applied Mechanics and Materials 339 (July 2013): 483–88. http://dx.doi.org/10.4028/www.scientific.net/amm.339.483.

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The purpose of this study was to design a dual-axis load cell that is suitable for measuring force load in kayak paddling. We used Finite Element Method (FEM) to analyze the change in stain profile of the dual axis load cell under different loading condition by alternating different strain gage placements for measuring the effects on coupled force and maximum strain output for determining the optimal placement sites of strain gage for designing the dual-axis load cell. The results of this study indicated that the size and placement sites were suitable for measuring force load in kayak paddling.
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41

Tateyama, Kohei, and Hiroyuki Yamada. "Nonuniform Deformation of Cell Structures Owing to Plastic Stress Wave Propagation." Applied Mechanics 2, no. 4 (November 5, 2021): 911–31. http://dx.doi.org/10.3390/applmech2040053.

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In cell structures, unlike in dense bodies, nonuniform deformation occurs from the impact end, even at velocities in the order of tens to hundreds of meters per second. In this study, we experimentally examine the nonuniform deformation mechanism of cell structures. They prepared two kinds of specimens: nickel foam (Ni foam) and silicone-rubber-filled nickel foam (Ni/silicone foam). As a dynamic and impact test method (compression velocity of 20 m/s or more), we used a dynamic and impact load-measuring apparatus with opposite load cells to evaluate the loads on both ends of the specimen in one test. At compression velocities of 20 m/s or less, no nonuniform deformations were observed in the Ni foam and the Ni/silicone foam, and the loads on the impact and the fixed ends achieved force equilibrium. The Ni foam showed no change with an increasing strain rate, and the Ni/silicone foam showed a strong strain rate dependence of the flow stress. At a compression velocity of approximately 26 m/s, the loads differed at the two ends of the Ni/silicone foam, and we observed nonuniform deformation from the impact end. The results of the visualization of the load and deformation behavior obtained from both ends of the specimen revealed that the velocity of the plastic stress wave and the length of the specimens are important for nonuniform deformation.
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42

Naseri, Sedigheh, Mariela Mejia Cordova, Jessica Wenthe, Ann-Charlotte Hellström, Tanja Lövgren, Angelica Loskog, Emma Eriksson, and Gustav Ullenhag. "Abstract 3501: Induction of tumor cell apoptosis & immunogenic cell death by CD40L-armed oncolytic adenoviruses." Cancer Research 82, no. 12_Supplement (June 15, 2022): 3501. http://dx.doi.org/10.1158/1538-7445.am2022-3501.

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Abstract Low tumor immunogenicity and a cold tumor microenvironment are two main characteristics occurring in different cancer types responsible for immunotherapy resistance. Immunostimulatory gene therapy using oncolytic viruses (OVs) has been developed as a new promising cancer therapy for its capacity to induce an anti-tumor immune response and sensitize the non-responding patients to checkpoint blockade therapy. Lokon adenoviruses (LOAds) are serotype 5/35 oncolytic adenoviruses that in addition to their oncolytic capacity encode for immunostimulatory molecules. Here we have evaluated the anti-tumor effects of trimerized membrane-bound (TMZ)-CD40L-armed LOAd700 and TMZ-CD40L/4-1BBL-armed LOAd703 in a variety of solid tumors to understand the underlying tumor modulating mechanisms. A panel of eight different human solid cancer cell lines (T24, PEA2, Mel526, H727, Skov3, MiaPaca2, H29 and A549) was infected with LOAd(-), a virus without transgenes, LOAd700 or LOAd703 and assessed for their response in different assays. MTS assay was used to measure the cell viability, flow cytometry for evaluating the cell surface markers and luminescent assay for measuring apoptosis (caspase 3/7 activity). LOAd viruses efficiently killed all tested cell lines. However, the oncolytic capacity of CD40L-armed LOAd700 and LOAd703 was significantly higher than LOAd(-) in two cell lines, T24 and PEA2, which were found to express the CD40 receptor. Death receptor TRAIL-R1 was significantly upregulated in T24 infected with LOAd703 and PEA2 infected with either LOAd700 or LOAd703. TRAIL-R2 was upregulated post LOAd infection in 7/8 cell lines where the upregulation was significant in T24, PEA2 and H29. Interestingly, the immunogenic cell death marker calreticulin, a damage-associated molecular pattern (DAMP) known as an “eat-me” signal to dendritic cells, was upregulated post LOAd infection in all cell lines. The increase in calreticulin level was statistically significant in 4/8 cell lines (T24, PEA2, Mel526 and H29) post LOAd700 and/or LOAd703 infection. Furthermore, LOAd700 and LOAd703 increased the effector caspase 3/7 activity in 5/8 cell lines (T24, PEA2, Mel526, Skov3 and MiaPaCa2) indicating an augmented apoptosis level. In conclusion, CD40L-armed LOAd viruses were, in addition to their high oncolytic capacity, demonstrated to induce apoptosis. Upregulation of cell surface calreticulin as well as the death receptors TRAIL-R1 and -R2 indicated generation of a more immunogenic phenotype of cancer cells. Thus, our findings suggest that CD40L-armed LOAd viruses could be inducers of apoptosis and immunogenic cell death in a variety of cancer types with an augmented effect in cancer cells expressing the CD40 receptor. Citation Format: Sedigheh Naseri, Mariela Mejia Cordova, Jessica Wenthe, Ann-Charlotte Hellström, Tanja Lövgren, Angelica Loskog, Emma Eriksson, Gustav Ullenhag. Induction of tumor cell apoptosis & immunogenic cell death by CD40L-armed oncolytic adenoviruses [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 3501.
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43

Choudhary, Shailesh K., Nienke Vrisekoop, Christine A. Jansen, Sigrid A. Otto, Hanneke Schuitemaker, Frank Miedema, and David Camerini. "Low Immune Activation despite High Levels of Pathogenic Human Immunodeficiency Virus Type 1 Results in Long-Term Asymptomatic Disease." Journal of Virology 81, no. 16 (May 30, 2007): 8838–42. http://dx.doi.org/10.1128/jvi.02663-06.

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ABSTRACT Long-term asymptomatic human immunodeficiency virus (HIV)-infected individuals (LTA) usually have low viral load and low immune activation. To discern whether viral load or immune activation is dominant in determining progression to AIDS, we studied three exceptional LTA with high viral loads. HIV type 1 isolates from these LTA were as pathogenic as viruses from progressors in organ culture. Despite high viral loads, these LTA had low levels of proliferating and activated T cells compared to progressors, like other LTA. In contrast to those in progressors, HIV-specific CD4+ T-cell responses in these LTA were maintained. Thus, low immune activation despite a high viral load preserved HIV-specific T-cell responses and resulted in a long-term asymptomatic phenotype.
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44

Abdullah, Nor Hafizah, Tengku Farah Wahida Ku Chik, Fairul Azmin Zaraini, and Ahmad Ammar. "Load Cell Application in Rocket Thrust Measurement System." Applied Mechanics and Materials 225 (November 2012): 437–41. http://dx.doi.org/10.4028/www.scientific.net/amm.225.437.

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A load cell is an important component in measuring thrust generated by rocket in rocket technology research and development. It aims to test the rocket thrust in achieving the targeted objectives of the project. A load cell is a transducer that is used to convert a force into electrical signal and it usually consists of four strain gauges assembled in Wheatstone bridge configuration. The strain gauge converts the deformation (strain) to electrical signals. This conversion occurs in two stages. First, the strain gauges on the load cell will detect the deformation of load cell structure (tension or compression) and second, the strain gauge will convert the changes in the load cell in terms of voltage readings. Before the load cell can be used as the thrust sensor in rocket testing, it must undergo a calibration process to determine the relation between Load (kg) and Voltage (V). LabVIEW is used as a platform for data logging interface which is connected to the National Instrument hardware. National Instrument hardware acts as a signal conditioning which allow the voltage readings acquired by load cell to be collected and analyzed by LabVIEW. Each load cell has its own equation that links between force and voltage. The equation is used as a reference to convert the voltage reading to thrust.
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45

Park, Dong Jin, Min Kyu Kang, Jong Hyun Lee, Seok Soon Lee, and Hyo Seok Jung. "LOAD CELL DESIGN USING FIBER BRAGG GRATING SENSORS." International Journal of Modern Physics: Conference Series 06 (January 2012): 203–8. http://dx.doi.org/10.1142/s2010194512003182.

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A load cell is the representative converter that changes load to the quantity of electricity. The load cell is used to a large mechanical structure and offshore structures to measure the force. Currently, the load cell using electrical strain gauges are commonly used. Basic measuring principle of electrical strain gauge is the electrical method. A load cell with electrical strain gauges is not available in the electromagnetic and corrosion environment. A Fiber Bragg Grating (FBG) sensor is not affected by the EMI (Electro Magnetic Interference)/EMC (Electro Magnetic Compatibility) and is strong in corrosion under the sea water. In this paper, we use the FBG sensors to make a load cell under the sea water condition and the electromagnetic environment and show FBG sensors' availability.
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46

Nikolaev, Y. E., V. N. Osipov, and V. Y. Ignatov. "Calculation methodology of the energy indicators of an self-contained energy complex including gas turbine plants, wind-driven power plant and electric storage cell." Power engineering: research, equipment, technology 22, no. 3 (September 8, 2020): 36–43. http://dx.doi.org/10.30724/1998-9903-2020-22-3-36-43.

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To supply small cities with electric and thermal energy it is proposed to create selfcontained energy complex based on gas turbine plants (GTP), wind generators and electric storage cell. A scheme for the joint operation of these plants is offered, a methodology for calculating the quantitative characteristics of a wind power plant, gas turbines and electric storage cell is developed. Electric storage cell provide coverage the peak portion of the daily electrical load curve. The heat load is ensured by the operation of the waste-heat boiler and the peak boiler. Using the example of a power complex with an electric load of 5 MW and a heat load of 17.5 MW, the generation of electric energy by wind driven power plant and gas turbine plants, the supply of electric energy from electric storage cell, the heat loads of the waste-heat boiler and peak boiler by months of the year are calculated. When the power share of the wind power plant is 0.2, the electric storage cell provide for an annual period from 5.2 to 10.7 % of the daily demand of the electric load schedule. The electric power of the gas turbine plant in winter is reduced to 70 % of the maximum load of the consumer, in summer - up to 55 %. An increase in the relative share of the power of a WDPP reduces the electric capacity of a gas turbine plants, its cost, while the cost of electric storage cell increases.
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47

Mandayatma, Eka. "PENINGKATAN RESOLUSI SENSOR LOAD CELL PADA TIMBANGAN ELEKTRONIK." JURNAL ELTEK 16, no. 1 (August 21, 2018): 37. http://dx.doi.org/10.33795/eltek.v16i1.85.

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Electronic scales are heavy gauges that are widely used both in the laboratory and in the business world. One of the main sensors of electronic scales is the load cell. The direct use of load cell will result in the achievement of the standard resolution of the load cell or ADC system used, so the resolution of the scales will be quite low as it is determined only by the load cell measurement range and the ADC resolution where the dynamic range of the ADC is not reached.In this article will be made electronic efforts to increase the resolution of the scales so that the accuracy of weighing can be better. Improved resolution attempts are made with electronic signal processor and conditioners, among others, by amplifying, summing and leveling amplifiers and to prevent noise being attempted by filtering. Data processing is done by comparing the resolution value of Load cell without signal conditioner and load cell resolution with signal conditioner. Load Cell with a load range of 0 - 5 kg in conditioning with 200x gain obtained output 113 mV to 1200 mV. With a standard ADC at a resolution of 20 mV / bit will be obtained 0000 0110 to 0011 1110 By adding a Leveling Amplifier circuit obtained output 48 mV for load 0 kg and 4.87 Volt for 5 kg load, ADC output in the range 0000 0010 to 1111 1100. Usage ADC without leveling 21% and with 98% leveling. Without leveling weighing resolution is 89 grm / bit and with 20 grm / bit leveling. Increased weighing resolution of 345%.
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48

Kwon, Oh Sung, Yongkyu Choi, Ohkyun Kwon, and Myoung Mo Kim. "Comparison of the Bidirectional Load Test with the Top-Down Load Test." Transportation Research Record: Journal of the Transportation Research Board 1936, no. 1 (January 2005): 108–16. http://dx.doi.org/10.1177/0361198105193600113.

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For the past decade, the Osterberg testing method (O-cell test) has been proved advantageous over the conventional pile load testing method in many aspects. However, because the O-cell test uses a loading mechanism entirely different from that of the conventional pile loading testing method, many investigators and practicing engineers have been concerned that the O-cell test would give inaccurate results, especially about the pile head settlement behavior. Therefore, a bidirectional load test using the Osterberg method and the conventional top-down load test were executed on 1.5-m diameter cast-in-place concrete piles at the same time and site. Strain gauges were placed on the piles. The two tests gave similar load transfer curves at various depth of piles. However, the top-down equivalent curve constructed from the bidirectional load test results predicted the pile head settlement under the pile design load to be approximately one half of that predicted by the conventional top-down load test. To improve the prediction accuracy of the top-down equivalent curve, a simple method that accounts for the pile compression was proposed. It was also shown that the strain gauge measurement data from the bidirectional load test could reproduce almost the same top-down curve.
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Cho, Jeong-Rae, Young Jin Kim, Jong-Won Kwark, Sung Yong Park, Won Jong Chin, and Byung-Suk Kim. "Load-Measuring Pot Bearing with Built-In Load Cell —Part I: Design and Performance." Engineering 05, no. 11 (2013): 856–64. http://dx.doi.org/10.4236/eng.2013.511104.

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Liu, Chun-Hung, and Li-Chun Wang. "Optimal Cell Load and Throughput in Green Small Cell Networks With Generalized Cell Association." IEEE Journal on Selected Areas in Communications 34, no. 5 (May 2016): 1058–72. http://dx.doi.org/10.1109/jsac.2016.2520218.

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