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1

Strichartz, Gary R., ed. Local Anesthetics. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71110-7.

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2

Handbook of local anesthesia. 3rd ed. St. Louis: Mosby Year Book, 1990.

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3

Handbook of local anesthesia. 4th ed. St. Louis: Mosby, 1997.

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4

Handbook of local anesthesia. 2nd ed. St. Louis: Mosby, 1986.

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5

1947-, Koren Gideon, ed. Eutectic mixture of local anesthetics (EMLA): A breakthrough in skin anesthesia. New York: M. Dekker, 1995.

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6

Bertil, Löfström J., and Sjöstrand Ulf H, eds. Local anaesthesia and regional blockade: Pharmacology, physiology, and clinical effects. Amsterdam: Elsevier, 1988.

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7

M, Neal Joseph, and Viscomi Christopher M, eds. Regional anesthesia: The requisites in anesthesiology. Philadelphia: Mosby, 2004.

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8

Anaesthesia and anaesthetics, general and local. Memphis, USA: General Books, 2012.

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9

W, Brown John, ed. Atlas of regional anesthesia. Norwalk, Conn: Appleton-Century-Crofts, 1985.

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10

Hanke, C. W., B. Sommer, and G. Sattler, eds. Tumescent Local Anesthesia. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-56744-5.

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11

Boezaart, André P. Atlas of regional blocks and anatomy for orthopedic anesthesia. Philadelphia, PA: Saunders, 2007.

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12

Saadatniaki, Asadolah. Clinical use of local anesthetics. Rijeka: InTech, 2012.

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13

Monika, Daubländer, and Fuder H, eds. Local anesthesia in dentistry. Chicago: Quintessence Pub. Co., 1993.

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14

Handbook of local anesthesia. 6th ed. St. Louis: Elsevier/Mosby, 2013.

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15

Malamed, Stanley F. Handbook of local anesthesia. 6th ed. St. Louis: Elsevier/Mosby, 2013.

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16

H, Rosenberg P., ed. Local and regional anaesthesia. London: BMJ Books, 2000.

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17

Haglund, J. Local anaesthesia in dentistry: Illustrated handbook on dental local anaesthesia. 7th ed. Södertälje, Sweden: Astra Läkemedel, 1986.

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18

Dosch, Mathias. Atlas of neural therapy with local anesthetics. 3rd ed. Stuttgart: Thieme, 2012.

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19

H, Whitehead F. Ivor, ed. Local anaesthesia in dentistry. 3rd ed. London: Wright, 1990.

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20

Howe, Geoffrey L. Local anaesthesia in dentistry. 3rd ed. London: Butterworth Scientific, 1990.

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21

1950-, Baart J. A., and Brand H. S, eds. Local anaesthesia in dentistry. Chichester, West Sussex: Blackwell, 2008.

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22

1952-, Bowdle T. Andrew, Horita Akira, and Kharasch Evan D, eds. The Pharmacologic basis of anesthesiology. New York: Churchill Livingstone, 1994.

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23

A, Paladini V., Rawal Narinder, and Tiengo Mario, eds. Regional anaesthesia, analgesia and pain management: Basics, guidelines and clinical orientation. Milano: Springer, 1999.

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24

W, Johnson R. Local and general anaesthesia for ophthalmic surgery. Oxford: Butterworth-Heinemann, 1994.

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25

C, DiMarco Arthur, and Naughton Doreen K, eds. Local anesthesia for dental professionals. Boston: Pearson, 2010.

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26

Bassett, Kathy. Local anesthesia for dental professionals. Upper Saddle River, N.J: Pearson, 2010.

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27

C, Grekin Roy, ed. Local anesthesia for dermatologic surgery. New York: Churchill Livingstone, 1991.

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28

Principles of anesthesiology: General and regional anesthesia. 3rd ed. Philadelphia: Lea & Febiger, 1993.

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29

Hans, Evers, ed. Introduction to dental local anaesthesia. Philadelphia: B.C. Decker, 1990.

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30

William, Harrop-Griffiths, ed. Regional nerve blocks and infiltration therapy: Textbook and color atlas. 3rd ed. Malden, Mass: Blackwell Pub., 2004.

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31

Allen, Brian F. S. Local Anesthetic Systemic Toxicity in Pregnancy. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0059.

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Local anesthetic systemic toxicity (LAST) is a concern for all practitioners who administer local anesthetics, including neuraxial and regional analgesia and anesthesia for pregnant patients. Toxicity can manifest as neurologic (e.g., seizure) or cardiac (e.g., dysrhythmia) sequelae and even death. Management of LAST differs from advanced cardiovascular life support (ACLS) in several important ways, and the parturient suffering LAST requires even more specific therapy. This chapter reviews the pathophysiology, assessment, and management of LAST in pregnancy, highlighting key differences from ACLS and LAST therapy in the nonpregnant patient. Prevention of this complication is also discussed. Knowledge of this material is essential for timely and appropriate care in order to ensure optional outcome.
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32

Grech, Dennis, and Laurence M. Hausman. Anesthetic Techniques. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190495756.003.0004.

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Anesthetic techniques for procedures performed outside the traditional operating room are varied. General anesthesia, sedation, and regional anesthesia can all be delivered in this venue. The choice of technique is based on safety considerations and patient comorbidities. Perioperative monitoring such as pulse oximetry, end-tidal carbon dioxide monitoring, and electrocardiography and blood pressure monitoring protocols must be consistent with American Society of Anesthesiologists guidelines. Common procedures include elective office-based anesthetics, emergency room sedations, endoscopic retrograde cholangiopancreatographies in the gastroenterology suite, and minimally invasive interventions in the radiology department. Because most of these locations have limited postanesthesia care unit capabilities, the patient’s rapid return to baseline functioning and the ability to be discharged quickly, safely, and comfortably are important goals. Thus, anesthetic technique and the pharmacokinetics and pharmacodynamics of the anesthetics, analgesics, antiemetics, and local anesthetics are of utmost importance.
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33

Barton, Joel, and Gavin Martin. Local Anesthesia Systemic Toxicity. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0087.

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Regional anesthesia can deliver multiple benefits to patients undergoing surgery. However, administering even appropriate doses of local anesthetic agents for regional anesthesia can be life threatening, and the risks must be well understood. Local anesthetic systemic toxicity (LAST) is a spectrum or sequence of symptoms and dysfunction that affects the nervous and cardiopulmonary systems. Management of LAST revolves around recognition, supportive care, and, specifically, administration of lipid emulsion. The American Society of Regional Anesthesia practice advisory for management of LAST is an excellent point-of-care reference for anesthesiologists practicing regional anesthesia.
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34

Golden, Alexandra Dubikovsky, and David Dickerson. Local Anesthetic Systemic Toxicity: Diagnosis, Prevention, and Management. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190271787.003.0043.

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Local anesthetic systemic toxicity is a major concern in both the inpatient and the outpatient setting, especially with the current increased use of regional, local, and tumescent anesthesia. Lack of protective strategies, delays in diagnosis, and the inability to provide timely lipid emulsion treatment are among the leading preventable causes to contribute to patients’ harm.
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35

Cole, Jacob, Victor Rivera, and Anthony Tucker. Tumescent Anesthesia in General Surgery. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190457006.003.0005.

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Tumescent anesthesia is a fairly novel anesthetic technique originating in dermatologic and cosmetic surgery. In the 30 years since this technique was first described, it has gradually gained wider acceptance as a viable anesthetic technique for a variety of procedures. This chapter discusses the development of the tumescent anesthesia technique including the benefits of tumescence over standard local anesthesia and the safety of the technique. Local anesthetic pharmacology and pharmacodynamics are reviewed along with the different additives that complement the tumescent solution formulation. Finally, this chapter reviews some of the more common procedures utilizing tumescent anesthesia.
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36

Perelmut, Robert, and Ernesto A. Pretto. Anesthetic Considerations in Homeland Disasters. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190495756.003.0032.

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This chapter will primarily focus on anesthetic considerations in homeland disasters likely to require the presence of the anesthesiologist in the out-of-hospital or prehospital environment. In order to understand the context within which anesthesiologists might be asked to function in the out-of-operating room setting during disaster response, we will provide a brief review of the disaster management functions of prehospital emergency medical services (EMS)/trauma systems. We will also describe the reorganization of hospital and intensive care services necessary to handle a surge of incoming critically injured or ill casualties. Our focus will be the role of the anesthesiologist, working in partnership with community or local EMS/trauma system and its network of hospitals, since the local EMS/ambulance system constitutes the basic functional unit of disaster medical response in the United States. We will end with a brief description of the major challenges we face in the delivery of intensive care services in mass and catastrophic casualty disasters.
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37

King, Adele, and Christopher McKee. Anesthetic Management of Pediatric Craniopharyngioma. Edited by Kirk Lalwani, Ira Todd Cohen, Ellen Y. Choi, and Vidya T. Raman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190685157.003.0045.

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The challenging perioperative management of craniopharyngiomas requires a multidisciplinary team approach. Though histologically benign, craniopharyngiomas are aggressive with local invasion and frequent recurrences. Significant morbidity maybe there at presentation. Treatment can worsen. Common perioperative concerns include hypothalamic dysfunction, tumor size and its effects on intracranial pressure, as well as the close proximity to nearby vessels and neural structures. Optimal anesthetic management includes thorough preoperative evaluation and planning with detailed knowledge of the tumor extent and symptomology. Management of hypothalamo-pituitary dysfunction plays a major role in achieving a successful outcome and should feature collaborative input from the endocrinology service.
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38

Harrison, John Henry, and Magdalena Anitescu. Neuraxial Anesthesia in Coexisting Neurologic Conditions. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190271787.003.0041.

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Some patients who need surgery may have coexisting neurologic disorders like multiple sclerosis, amyotrophic lateral sclerosis, peripheral neuropathies (e.g., Charcot-Marie-Tooth disease or Guillain-Barré syndrome), or muscular dystrophies (e.g., Duchenne’s or myotonic dystrophy). When neuraxial analgesia and anesthesia are indicated, the anesthesiologist should be aware of the risks and benefits of the technique. Neuraxial anesthesia is not absolutely contraindicated in nervous system diseases and there are undeniable benefits to ruling out general anesthesia. In patients with coexisting neurologic disorders, prolonged sensory and motor block can be confused with epidural hematoma and abscess when present. Minor nerve injury from local anesthetic cytotoxicity or ischemia and mechanical trauma may cause permanent nerve injury through the double crush phenomenon. Lower concentrations of local anesthetics are generally recommended.
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39

The 2006-2011 World Outlook for Antipruritics and Local Anesthetic Dermatological Skin Preparations. Icon Group International, Inc., 2005.

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40

Parker, Philip M. The 2007-2012 World Outlook for Antipruritics and Local Anesthetic Dermatological Skin Preparations. ICON Group International, Inc., 2006.

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41

Parker, Philip M. The 2007-2012 Outlook for Antipruritics and Local Anesthetic Dermatological Skin Preparations in Japan. ICON Group International, Inc., 2006.

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42

Parker, Philip M. The 2007-2012 Outlook for Antipruritics and Local Anesthetic Dermatological Skin Preparations in India. ICON Group International, Inc., 2006.

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43

Parker, Philip M. The 2007-2012 Outlook for Antipruritics and Local Anesthetic Dermatological Skin Preparations in Greater China. ICON Group International, Inc., 2006.

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44

Cheng, Paul K., Tariq M. Malik, and Magdalena Anitescu. Peripheral Nerve Block and Ultrasound Images. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190457006.003.0008.

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Ultrasound-guided peripheral nerve blocks can be used as the primary anesthetic for surgery involving the extremities and trunk and as a modality for opioid-sparing postoperative pain management. Success of regional anesthesia is dependent upon depositing local anesthetics in the correct plane. Advent of ultrasound has made this process more efficient, safer, and less painful for the patient More prevalent use of regional anesthesia in the perioperative setting will limit opioid prescription, development of chronic post surgical pain and is known to improve patient satisfaction by improving pain. This chapter reviews the history of ultrasound use for nerve blocks and basics of ultrasound use. It also discusses common peripheral nerve blocks of the upper extremities, trunk area, and lower extremities and summarizes indications, techniques, and key complications. Included are ultrasound images for each block.
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45

Waters, Janet. A Woman in Labor with Hypotension and Dyspnea After Epidural Placement. Edited by Angela O’Neal. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190609917.003.0022.

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This chapter discusses neurological complications of the administration of epidural and spinal anesthesia in the obstetric population. It begins with a case report on a patient with a total spinal block, which occurs when large doses of local anesthetic intended for the epidural space are inadvertently injected into the subarachnoid space. The chapter reviews key points in recognizing and treating this potentially fatal complication. It discusses other complications, including epidural hematoma, epidural abscess, spinal cord injury, and meningitis, as well as complications from intravascular injection of local anesthetic. Lastly, it discusses how to recognize and treat the most common complication of neuraxial block, post dural puncture headache.
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46

Parker, Philip M. The 2007-2012 Outlook for Antipruritics and Local Anesthetic Dermatological Skin Preparations in the United States. ICON Group International, Inc., 2006.

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47

Vydyanathan, Amaresh, Karina Gritsenko, Samer N. Narouze, and Allan L. Brook. Cervical Intra-Articular Facet Injection: Computed Tomography. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0009.

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Intra-articular facet joint injections commonly refer to the injection of a contrast media and local anesthetic solution, with or without corticosteroids, directly into the facet joint space. The purpose of this procedure is pain relief as well as to establish an etiological diagnosis for surgical interventions such as joint denervation or radiofrequency ablation. Medial branch block, or facet nerve block, refers to injection of local anesthetic and possible corticosteroids along the medial branch nerve supplying the facet joints. Cervical intra-articular and facet nerve block injections are often part of a work-up for general or focal neck pain, headaches, or cervical muscle spasms. There is limited evidence for short- and long-term pain relief with cervical intra-articular facet joint injections. Cervical medial branch nerve blocks with local anesthetics demonstrate moderate evidence for short- and long-term pain relief with repeat interventions, and strong evidence exists for long-term pain relief following cervical radiofrequency neurotomy.
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48

Local Anesthetics. Springer, 2011.

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49

Arthur, G. R., K. R. Courtney, B. G. Covino, J. M. Garfield, and Gary R. Strichartz. Local Anesthetics. Springer London, Limited, 2012.

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50

Local Anesthetics. Springer, 2011.

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