Relevant bibliographies by topics / Localisation de ARN

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Localisation de ARN'

Author: Grafiati
Published: 4 June 2021
Last updated: 17 February 2022

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Journal articles on the topic "Localisation de ARN"

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Basyuk, Eugenia, Brigitte Lavoie, Rémy Bordonné, and Édouard Bertrand. "Localisation des ARN dans le cytoplasme." médecine/sciences 20, no. 6-7 (2004): 669–73. http://dx.doi.org/10.1051/medsci/2004206-7669.

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SEYER, P., S. GRANDEMANGE, L. PESSEMESSE, F. CASAS, G. CABELLO, and C. WRUTNIAK-CABELLO. "L’activité mitochondriale est un régulateur majeur de la différenciation des myoblastes et de l’expression des isoformes de myosine." INRAE Productions Animales 19, no. 4 (2006): 279–86. http://dx.doi.org/10.20870/productions-animales.2006.19.4.3495.

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Parallèlement à son rôle dans le métabolisme énergétique, l’activité mitochondriale intervient également dans l’induction de l’apoptose, ainsi que dans la régulation de la prolifération et de la différenciation cellulaires. Il existe en particulier une véritable régulation de la différenciation des myoblastes par l’activité mitochondriale, indépendante de la production d’ATP. Elle implique notamment le contrôle de l’expression de myogénine et de l’activité des facteurs myogéniques.
 Dans cette étude, nous démontrons que l’expression du proto-oncogène c-Myc est respectivement stimulée ou diminuée par une inhibition ou une stimulation de l’activité mitochondriale. Cette régulation s’effectue en grande partie au niveau de la stabilité du messager, et au niveau de la localisation cellulaire de la protéine dans les myoblastes aviaires. De plus, la surexpression de c-Myc reproduit très exactement les effets d’une inhibition de l’activité mitochondriale : i) abrogation de la différenciation terminale ; ii) inhibition de l’expression de Myogénine, sans altération de celle de MyoD ; iii) blocage de l’aptitude des facteurs myogéniques à induire la différenciation ; iv) inhibition de la sortie des myoblastes du cycle cellulaire. Ces résultats démontrent que c-Myc est une cible importante de l’activité mitochondriale, impliquée dans l’influence de l’organite sur la différenciation des myoblastes.
 Nous avons également mis en évidence l’existence d’un autre gène cible de l’organite qui code la phosphatase calcium dépendante Calcineurine. Son expression est respectivement inhibée ou stimulée par l’inhibition ou la stimulation de l’activité mitochondriale. De plus, l’expression d’une forme constitutivement active de Calcineurine stimule la différenciation des myoblastes et l’expression de Myogénine, alors que ces deux événements sont bloqués par l’expression d’un ARN antisens Calcineurine. Enfin, la stimulation de l’activité mitochondriale, comme l’expression d’une forme constitutivement active de Calcineurine stimule spécifiquement l’expression de l’isoforme lente des chaînes lourdes de myosine.
 Ces données démontrent donc que, notamment via l’expression de Calcineurine, l’activité mitochondriale régule non seulement la différenciation des myoblastes, mais détermine également le type contractile des fibres musculaires
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Seno, Aldyandra Hami, and Ferri M. H. Aliabadi. "A Comparative Study of Impact Localisation in Composite Structures Using Neural Networks under Environmental and Operational Variations." Key Engineering Materials 827 (December 2019): 410–15. http://dx.doi.org/10.4028/www.scientific.net/kem.827.410.

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In this study we compare the effectiveness of the Normalised Smoothed Envelope (NSET) method for Artificial Neural Network (ANN) based impact localisation under simulated environmental and operational conditions with respect to other ANN based localisation methods developed by other studies. It is shown that when the testing and training impact case is the same, most studies give comparably good accuracy of localisation irrespective of feature extraction method or structure geometry. However, when the testing and training impact cases are not the same, only the NSET method is able to negate the variations caused by various impact cases and provide good localisation accuracy for an ANN trained using only a single impact case thus allowing for smaller training data set size requirements and increasing feasibility for real life application.
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Stevens, C. R., M. Benboubetra, R. Harrison, T. Sahinoglu, E. C. Smith, and D. R. Blake. "Localisation of xanthine oxidase to synovial endothelium." Annals of the Rheumatic Diseases 50, no. 11 (1991): 760–62. http://dx.doi.org/10.1136/ard.50.11.760.

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Mapp, P. I., and P. A. Revell. "Ultrastructural localisation of muramidase in the human synovial membrane." Annals of the Rheumatic Diseases 46, no. 1 (1987): 30–37. http://dx.doi.org/10.1136/ard.46.1.30.

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Rees, J. A., S. Y. Ali, and R. A. Brown. "Ultrastructural localisation of fibronectin in human osteoarthritic articular cartilage." Annals of the Rheumatic Diseases 46, no. 11 (1987): 816–22. http://dx.doi.org/10.1136/ard.46.11.816.

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Rees, J. A., and S. Y. Ali. "Ultrastructural localisation of alkaline phosphatase activity in osteoarthritic human articular cartilage." Annals of the Rheumatic Diseases 47, no. 9 (1988): 747–53. http://dx.doi.org/10.1136/ard.47.9.747.

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Galdo, Francesco Del, Peter J. Wermuth, Sankar Addya, Paolo Fortina та Sergio A. Jimenez. "NFκB activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of nephrogenic systemic fibrosis". Annals of the Rheumatic Diseases 69, № 11 (2010): 2024–33. http://dx.doi.org/10.1136/ard.2010.134858.

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ObjectiveNephrogenic systemic fibrosis (NSF) is a generalised fibrotic disorder occurring in certain individuals with renal insufficiency exposed to gadolinium-based contrast agents (GdBCA) for MRI. Histopathological examination of affected tissues shows increased numbers of activated macrophages. To elucidate the mechanisms responsible for macrophage activation, the effects of the GdBCA Omniscan on normal human macrophage global gene expression, chemokine production and nuclear factor κB (NFκB) activation was examined.MethodsNormal human monocyte-derived macrophages were incubated with Omniscan (50 mM) and their gene expression analysed by microarrays and real-time PCR. Macrophage chemokine production was assayed by multiplex ELISA. NFκB activation was assessed by NFκB nuclear localisation and quantitation of intracellular levels of inducible nitric oxide synthase (iNOS) protein. A specific cell-permeable NFκB peptide inhibitor was used to abrogate NFκB stimulation of chemokine and iNOS protein levels. CCL8/MCP-2 in affected skin of patients with NSF was examined by indirect immunofluorescence.ResultsOmniscan caused a profound change in the transcriptome of differentiated human normal macrophages in vitro, including a large increase in the expression of genes encoding CC and CXC chemokines. It induced rapid nuclear localisation of NFκB and stimulation of iNOS protein levels and chemokine production which were blocked by an NFκB inhibitory peptide. CCL8/MCP-2, the most upregulated chemokine following in vitro macrophage exposure to Omniscan, was strongly increased in NSF-affected skin.ConclusionThe GdBCA Omniscan induces potent stimulation of macrophage gene expression, NFκB activation and increased NFκB-mediated production of CC and CXC chemokines and iNOS. These alterations may play a crucial role in the pathogenesis of NSF.
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Konttinen, Y. T., V. Bergroth, M. Kulomaa, et al. "Localisation of lysozyme mRNA in rheumatoid synovial membrane by in situ hybridisation." Annals of the Rheumatic Diseases 48, no. 11 (1989): 912–17. http://dx.doi.org/10.1136/ard.48.11.912.

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Boileau, C., F. Poirier, J.-P. Pelletier, et al. "Intracellular localisation of galectin-3 has a protective role in chondrocyte survival." Annals of the Rheumatic Diseases 67, no. 2 (2007): 175–81. http://dx.doi.org/10.1136/ard.2006.066514.

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Dissertations / Theses on the topic "Localisation de ARN"

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Roberge, Denise. "Expression et localisation cellulaire des ARN hY." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0020/MQ56963.pdf.

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Kaltimbacher, Valérie. "Appréhension de la biogenèse mitochondriale par la localisation des ARN messagers sur la surface mitochondriale : expression allotopique dans le noyau de gènes mitochondriaux et identification de nouvelles protéines mitochondriales par les puces à ADN." Paris 6, 2007. http://www.theses.fr/2007PA066226.

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Les protéines mitochondriales codées par le noyau sont importées dans la mitochondrie selon une voie post-traductionnelle ou co-traductionnelle. Cette dernière nécessite la localisation des ARNm sur la surface mitochondriale. En identifiant les ARNm se localisant sur la surface mitochondriale par les puces à ADN, nous souhaitons développer un outil de prédiction des protéines mitochondriales chez la souris. Une grande partie des pathologies mitochondriales est causée par des mutations de l’ADN mitochondrial. La thérapie génique par l’expression allotopique de ces gènes présente des limitations importantes liées à l’hydrophobie des protéines. Nous avons développé cette stratégie pour les gènes ATP6 et ND4 qui sont impliqués dans les pathologies NARP et LHON. Les séquences d'adressage à la surface mitochondriale (MTS et 3' UTR) des gènes nucléaires SOD2 et COX10 ont été associées aux gènes ATP6 et ND4 respectivement. Elles ont permis le transport des transcrits à la surface mitochondriale assurant ainsi la translocation mitochondriale de leur produit et une restitution complète de la fonction de la chaîne respiratoire dans des fibroblastes des patients
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Zytnicki, Matthias Schiex Thomas Gaspin Christine. "Localisation d'ARN non-codants par réseaux de contraintes pondérées." Toulouse (Université Paul Sabatier, Toulouse 3), 2008. http://thesesups.ups-tlse.fr/236.

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Garcia, Mathilde. "Localisation d'ARNm et biogenèse mitochondriale chez la levure Saccharomyces cerevisiae." Paris 7, 2009. http://www.theses.fr/2009PA077044.

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La localisation d'ARN messagers, en assurant une production protéique locale, constitue un processus important pour l'édification de structures complexes et leur remodelage en fonction de la physiologie cellulaire. Les mitochondries constituent, à cet égard, un exemple fascinant d'organisation supramoléculaire. Elles résultent de l'assemblage en divers complexes de près de 800 protéines pour la plupart codées dans le génome nucléaire et traduites dans le cytoplasme. Il a précédemment été montré qu'une fraction importante de ces protéines est traduite au voisinage de la mitochondrie chez la levure Saccharomyces cerevisiae. Au cours de ma thèse, je me suis attachée à comprendre le rôle et les mécanismes de la traduction site-spécifique impliquée dans la biogenèse mitochondriale. Ces études ont nécessité le développement de deux méthodes d'analyses quantitatives de la localisation des ARN : une approche biochimique basée sur l'analyse par PCR quantitative ou puces à ADN de fractionnements mitochondriaux et une approche in vivo basée sur une hybridation in situ fluorescente suivie d'une analyse quantitative des distances intracellulaires. Mon travail de thèse a permis de souligner l'importance des processus post-transcriptionnels pour la biogenèse de la mitochondrie. Ainsi, la protéine PuDp de liaison aux ARNm contrôle la localisation mitochondriale d'un sous groupe d'ARN messagers codant des protéines impliquées dans les étapes précoces de la biogenèse mitochondriale. Pour d'autres ARN messagers comme ATP2 la traduction site-spécifique serait le résultat d'un couplage entre les processus de traduction et d'import protéique mitochondrial. Puisque des ARN messagers appartenant à des classes fonctionnelles distinctes utilisent des modalités différentes pour sélectionner leur site de traduction, nous proposons un modèle de biogenèse mitochondriale basée sur des groupes d'ARN messagers co-régulés au niveau post-transcriptionnel<br>Heterogeneous macromolecules distribution leads to specialized cellular domains. Messenger RNA localization and local protein production are important processes for complex cellular structure building and remodelling with physiology changes. In that respect, mitochonEria are a fascinating example of supramolecular organization. They come from the assembling in various complexes of 800 proteins most of them encoded by nuclear gènes and synthesized by cytoplasmic ribosomes. We previously showed that, in yeast Saccharomyces cerevisiae, a large fraction of thèse proteins are translated in the vicinity of mitochondria. During my PHD studies, I analysed the role and the mechanism underlying this site-specific translation phenomenon. In that goal, we developed two quantitative analyse of RNA localisation: a biochemical approach based on quantitative PCR or microarray analysis of mitochondrial fractions and an in vivo approach based on fluorescent in situ hybridization followed by quantitative cell distances analysis. My results emphasize how important are post-transcriptional process in mitochondrial biogenesis. For instance, PuDp mRNA binding protein control the mitochondrial localization of a sub-class of messenger RNA encoding proteins responsible for the early steps of mitochondrial biogenesis. For others, like ATP2 mRNA, site-specific translation seems to be the result of a coupling of their translation and mitochondrial protein import. Since messenger RNA implicated in distinct mitochondrial functions use different pathway to determine their translation site, we propose a model of coordinated biogenesis of mitochondria based on mRNA groups co-regulated at post-transcriptional level
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Goussard, Sébastien. "Etude de la localisation mitochondriale de l'ARNm ATP2 chez Saccharomyces cerevisiae." Paris 7, 2012. http://www.theses.fr/2012PA077113.

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Ma thèse porte sur la traduction localisée d'ARNm à la surface mitochondriale. Le phénomène de traduction localisée fait correspondre le site de traduction d'un ARNm et le site d'action de la protéine produite. 60% des protéines de la mitochondrie codées dans le génome nucléaire ont leur ARNm traduits à la surface de la mitochondrie. Il y a deux classes d'ARNm focalisés à la mitochondrie. Les ARNm de classe I dépendent de la protéine liant l'ARN Puf3p pour être localisés à la mitochondrie mais pas ceux de classe II. L'identification de signaux en cis sur PARNm de ATP2, transcrit de classe II, a été effectuée par une méthode combinant des expériences de FISH et des analyses statistiques rigoureuses des images, permettant de déterminer la proportion de cellules d'une population où cet ARNm est localisé à la mitochondrie. La traduction et le MTS (mitochondrial targetting séquence), ainsi que les régions RI et R2 sont essentielles à la localisation asymétrique de l'ARNm de ATP2. Au cours de ma thèse, j'ai réduit la taille de la région R2 de la moitié du gène ATP2 à ses 200 dernières bases. J'ai pu montré que deux ARNm constitués des mêmes régions codantes mais dans un ordre différent étaient enrichis dans des proportions différentes à la surface mitochondriale. Selon que le gène rapporteur LacZ soit fusionné en 3' ou en 5' du gène ATP2, la proportion de cellules où l'ARNm est localisé passe du simple au double. J'ai effectué des expériences de séparation de polysomes sur gradient de sucrose afin de déterminer la dynamique de traduction de ces ARNm. La traduction des ARNm fortement enrichis dans la fraction mitochondriale semble peu efficace<br>My thesis is upon mRNA's localized translation at the proximity of mitochondria. The translation localization phenomena allows an mRNA to be translated at the same site it's protein acts. 60% of nuclear genome encoded mitochondrial proteins are translated on the mitochondrial surface. There is two classes of mRNA localized to mitochondria. Class l's mRNA necessit the RNA binding protein Puf3p to be localized, which is not the case of class IF s mRNA. The identification of cis acting signals in ATP2 mRNA, a class II transcript, has been done using a method combining FISH experiments and statistical analyzes of pictures, allowing the determination of the proportion of cells where the mRNA is localized on mitochondria's surface. The translation, the MTS (mitochondrial targetting sequence) and two regions, RI and R2, are essentials to ATP2's mRNA mitochondrial localization. During my Ph. D, I reduced region R2 size from half ATP2 length to the 200 last bases. I showed that two RNA formed of the same coding regions but in a different order are not enriched in the same proportion in mitochondrial fraction. The proportion of cells where the mRNA is localized to mitochondria double wether the raporter gene LacZ is at the 3' or 5' of ATP2 gene. I've done sucrose gradient polysomes separation experiments to establish the translations dynamic of those mRNA. It seems that the translation of mRNA highly enriched in mitochondria's fraction is less efficient
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Zytnicki, Matthias. "Localisation d'ARN non-codants par réseaux de contraintes pondérées." Toulouse 3, 2007. http://thesesups.ups-tlse.fr/236/.

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La recherche d'ARN non-codants (ARNnc) a reçu un regain d'intérêt suite à la découverte de nouveaux types d'ARNnc aux fonctions multiples. De nombreuses techniques ont été développées pour localiser ces ARN dans des séquences génomiques. Nous utilisons ici une approche supposant la connaissance d'un ensemble d'éléments de structure discriminant une famille d'ARNnc appelé signature. Dans cette approche, nous combinons plusieurs techniques de pattern-matching avec le formalisme des réseaux de contraintes pondérées afin de modéliser simplement le problème, de décrire finement les signatures et d'attribuer un coût à chaque solution. Nos travaux nous ont conduit à élaborer plusieurs techniques de filtrage ainsi que des algorithmes de pattern-matching originaux que nous présentons ici. Nous avons de plus conçu un logiciel, appelé DARN!, qui implante notre approche, ainsi qu'un module de génération de signatures. Ceux-ci permettent de rechercher efficacement de nouveaux ARNnc<br>Following recent discoveries about the several roles of non-coding RNAs (ncRNAs), there is now great interest in identifying these molecules. Numerous techniques have been developed to localize these RNAs in genomic sequences. We use here an approach which supposes the knowledge of a set of structural elements called signature that discriminate an ncRNA family. In this work, we combine several pattern-matching techniques with the weighted constraint satisfaction problem framework. Together, they make it possible to model our biological problem, to describe accurately the signatures and to give the solutions a cost. We conceived filtering techniques as well as novel pattern-matching algorithms. Furthermore, we designed a software called DARN! that implements our approach and another tool that automatically creates signatures. These tools make it possible to localize efficiently new ncRNAs
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Thebault, Patricia. "Formalisme CSP (Constraint Satisfaction Problem) et localisation de motifs structurés dans les textes génomiques." Phd thesis, Université Paul Sabatier - Toulouse III, 2004. http://tel.archives-ouvertes.fr/tel-00011452.

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La recherche d'occurrences de gènes d'ARN dans les séquences<br /> génomiques est un problème dont l'importance est renouvelée par la<br /> découverte récente de très nombreux ARN fonctionnels, opérant<br /> souvent en interaction avec d'autres molécules.<br /><br />Le formalisme des réseaux de contraintes est approprié à cette problématique aussi bien sur le plan de la modélisation que sur les développements algorithmiques qu'il permet de proposer. <br /><br /> Après une analyse et une comparaison des outils existants plongés dans le cadre des réseaux de contraintes, nous<br /> montrons comment l'utilisation conjointe des réseaux de contraintes,<br /> des techniques de résolution associées et des algorithmes et<br /> structures de données du "pattern matching" permet de modéliser et de<br /> rechercher efficacement des motifs structurés en interaction (faisant<br /> intervenir plusieurs textes génomiques simultanément).
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Prod'Homme-Gentil, Delphine. "Détection et étude de la localisation de l'ARN polymérase ARN-dépendante du virus de la mosai͏̈que jaune du navet (TYMV)." Paris 7, 2002. http://www.theses.fr/2002PA077157.

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Davezac, Noélie. "La Phosphatase CDC25B : bases moléculaires de sa localisation intra-cellulaire et recherche de nouveaux partenaires." Toulouse 3, 2001. http://www.theses.fr/2001TOU30162.

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Viranaicken, Wildriss. "Etude structurale et fonctionnelle des facteurs Ilf3 et NF90, deux protéines impliquées dans le routage intracellulaire des ARN messagers." Paris 6, 2005. http://www.theses.fr/2005PA066365.

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Books on the topic "Localisation de ARN"

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François, Djindjian, Oosterbeek Luís, and International Union of Prehistoric and Protohistoric Sciences., eds. Symbolic spaces in prehistoric art: Territories, travels and site locations = Espaces symboliques dans l'art préhistorique : territoires, déplacements et localisation des sites. Archaeopress, 2009.

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International Congress of Prehistoric and Protohistoric Sciences (15th 2006 Lisbon, Portugal). Symbolic spaces in prehistoric art: Territories, travels and site locations = Espaces symboliques dans l'art préhistorique : territoires, déplacements et localisation des sites. Archaeopress, 2009.

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Gardner, Howard. Art, mind, and brain: A cognitive approach to creativity. Basic Books, 1985.

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Migration, Transmission, Localisation: Visual Art in Singapore. National Gallery Singapore, 2019.

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Prout, Jeremy, Tanya Jones, and Daniel Martin. Regional anaesthesia. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199609956.003.0019.

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The regional anaesthesia chapter discusses the pharmacology of local anaesthetic agents, techniques of nerve localisation, practical aspects of ultrasound-guided blocks and the advantages and complications of regional anaesthesia. Common, and clinically useful, blocks for the upper and lower limb are described in detail with pictures of anatomical landmarks and ultrasound appearance to compliment the description. Indications, technique, volumes required and complications are described for each block.
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Kipps, Christopher, and John Hodges. Clinical cognitive assessment. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199644957.003.0010.

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Cognitive symptoms arise from the location of brain dysfunction and are not linked directly to any particular pathology. In the early stages of disease, symptoms may be non-specific, and while certain symptom clusters are commonly seen in particular disorders, atypical presentations are not infrequent. For example, in Alzheimer’s disease, patients may present with a focal language syndrome instead of the more commonly appreciated autobiographical memory disturbance despite identical pathology. In our approach to the cognitive assessment, we maintain a symptom oriented approach. This facilitates the localisation of pathology and subsequent clinical diagnosis, which may then be supplemented by associated neurological signs, imaging or other investigations.
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Panicker, Jalesh N., and Clare J. Fowler. Non-traumatic neurourology. Edited by Christopher R. Chapple. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0046.

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This chapter reviews bladder disturbances in non-traumatic neurological conditions and provides an approach to its evaluation and management. The pattern of bladder dysfunction depends upon the level of neurological localisation and accordingly, lesions can be suprapontine, infrapontine/suprasacral (spinal), or infrasacral. The importance of the frontal lobes for bladder control has been confirmed and vascular disease or tumour can result in incontinence. There is better understanding about the very different urological profile of the two sometimes confused conditions, multiple system atrophy and Parkinson’s disease. Guidelines for the management of lower urinary tract dysfunction in multiple sclerosis are reviewed. Lower urinary tract (LUT) dysfunction is common in neurological disease and its importance to patient health and quality of life is now widely recognized.
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Schmidt, Dieter, and Simon Shorvon. Resecting Epilepsy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198725909.003.0005.

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The evolution of surgery for epilepsy in the late nineteenth century was partly the consequence of new ideas about the localisation of function in the brain and advances in the understanding of the physiological nature of epilepsy. This was an exciting time of discovery, and really fundamental and novel principles were enunciated which have stood the test of time. New techniques of investigation, including electroencephalography or magnetic resonance imaging, have since led to more accurate ‘targeting’, allowing the elucidation of the anatomical underpinning of epilepsy to be based, not only on semiology as in the earlier years, but also on more objective structural and functional measures. However, the fact remains that most surgery is based on the concept that resecting ‘bad’ tissue, and thus removing the ‘focus’ of epilepsy, will cure the condition—a postulation which has not changed since the time of Jackson (and which has its roots in earlier superstition). Such theories of epilepsy are surely gross simplifications, and the absence of any subsequent paradigm shift is why surgery has really not advanced conceptually much in the last 50 years. Technique and technology have profoundly changed, but the theoretical basis, generally speaking, has not.
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O'Sullivan, Carol, and Jean-François Cornu, eds. The Translation of Films, 1900-1950. British Academy, 2019. http://dx.doi.org/10.5871/bacad/9780197266434.001.0001.

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This rich collection of essays by film historians, translation scholars, archivists, and curators presents film translation history as an exciting and timely area of research. It builds on the last 20 years of research into the history of dubbing and subtitling, but goes further, by showing how subtitling, dubbing, and other forms of audiovisual translation developed over the first 50 years of the 20th century. This is the first book-length study, in any language, of the international history of audiovisual translation to include silent cinema. Its scope covers national contexts both within Europe and beyond. It shows how audiovisual translation practices were closely tied to their commercial, technological, and industrial contexts. The Translation of Films, 1900–1950 draws extensively on archival sources and expertise, and revisits and challenges some of the established narratives around film languages and the coming of sound. For instance, the volume shows how silent films, far from being straightforward to translate, went through a complex process of editing for international distribution. It also closely tracks the ferment of experiments in film translation during the transition to sound from 1927 to 1934 and later, as markets adjusted to the demands of synchronised film. The Translation of Films, 1900–1950 argues for a broader understanding of film translation: far from being limited to language transfer, it encompasses editing, localisation, censorship, paratextual framing, and other factors. It advocates for film translation to be considered as a crucial contribution not only to the worldwide circulation of films, but also to the art of cinema.
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Book chapters on the topic "Localisation de ARN"

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Chen, Shen, and Thi Thuy Le. "Teaching culture for localisation." In Teaching of Culture in English as an International Language. Routledge, 2018. http://dx.doi.org/10.4324/9781351027182-6.

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Celeste, Edoardo, and Federico Fabbrini. "Competing Jurisdictions: Data Privacy Across the Borders." In Palgrave Studies in Digital Business & Enabling Technologies. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-54660-1_3.

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Abstract Borderless cloud computing technologies are exacerbating tensions between European and other existing regulatory models for data privacy. On the one hand, in the European Union (EU), a series of data localisation initiatives are emerging with the objective of preserving Europe’s digital sovereignty, guaranteeing the respect of EU fundamental rights and preventing foreign law enforcement and intelligence agencies from accessing personal data. On the other hand, foreign countries are unilaterally adopting legislation requiring national corporations to disclose data stored in Europe, in this way bypassing jurisdictional boundaries grounded on physical data location. The chapter investigates this twofold dynamic by focusing particularly on the current friction between the EU data protection approach and the data privacy model of the United States (US) in the field of cloud computing.
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Manaysay, Ferth Vandensteen, and Jovanie Camacho Espesor. "Frictional Binaries: Hybridity, Civil Society, and Liberal-Local Peacebuilding in Mindanao." In Operationalisation of Hybrid Peacebuilding in Asia. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-67758-9_6.

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AbstractInternational and local civil society organisations have usually been identified amongst the key actors for the conceptual and practical development of liberal and post-liberal peace approaches. The concept of hybrid peacebuilding, for example, has highlighted the need to empower local civil society groups. Critics of the ‘local turn’ in peacebuilding, however, argue against the conceptual idealisation of hybridity. Using examples from Mindanao, this chapter contends that the debates on liberal-local hybridity can most meaningfully gain from asking questions not only about the processes of internationalisation and localisation, but also about the ways in which hybrid mechanisms are able to produce more or less stable outcomes. By turning into the agency of civil society actors, it suggests that the concept of hybridity, which is often represented using dichotomised categories (e.g. ‘liberal-international’ and ‘illiberal-local’), tends to oversimplify the conceptual intricacies and dynamic processes between top-down and bottom-up approaches. The analysis in the chapter aims to contribute to the discussions on hybridity by illustrating the manner civil society actors are able to negotiate their complexities within the frictional binaries of liberal ideas, institutions and resources vis-à-vis local practices, power relations and norms.
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Stanier, Jessica, and Nicole Miglio. "Painful Experience and Constitution of the Intersubjective Self: A Critical-Phenomenological Analysis." In The International Library of Bioethics. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-65613-3_8.

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AbstractIn this paper, we discuss how phenomenology might cogently express the way painful experiences are layered with complex intersubjective meaning. In particular, we propose a critical conception of pain as an intricate multi-levelled phenomenon, deeply ingrained in the constitution of one’s sense of bodily self and emerging from a web of intercorporeal, social, cultural, and political relations. In the first section, we review and critique some conceptual accounts of pain. Then, we explore how pain is involved in complex ways with modalities of pleasure and displeasure, enacted personal meaning, and contexts of empathy or shame. We aim to show why a phenomenology of pain must acknowledge the richness and diversity of peculiar painful experiences. The second section then weaves these critical insights into Husserlian phenomenology of embodiment, sensation, and localisation. We introduce the distinction between Body-Object and Lived-Body to show how pain presents intersubjectively (e.g. from a patient to a clinician). Furthermore, we stress that, while pain seems to take a marginal position in Husserl’s whole corpus, its role is central in the transcendental constitution of the Lived-Body, interacting with the personal, interpersonal, and intersubjective levels of experiential constitution. Taking a critical-phenomenological perspective, we then concretely explore how some people may experience structural conditions which may make their experiences more or less painful.
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Sabchev, Tihomir, Sara Miellet, and Elif Durmuş. "Human Rights Localisation and Individual Agency: From ‘Hobby of the Few’ to the Few Behind the Hobby." In Myth or Lived Reality. T.M.C. Asser Press, 2021. http://dx.doi.org/10.1007/978-94-6265-447-1_8.

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AbstractHuman rights have been facing criticism on many fronts, including the challenges of the “enforcement gap” and the “citizenship gap”, laying bare the shortcomings with regard to the implementation of human rights law as well as regarding its protection of highly vulnerable groups such as refugees. Research on the effectiveness of human rights, the “localisation” of human rights through invocations and practices on the ground, the increased engagement of local authorities with human rights, are all responses to such challenges to some degree. Based on empirical research conducted within municipalities in four countries, this chapter focuses on a missing piece of the puzzle in terms of conceptual and empirical research: the role of “individual agency”. We adopt a socio-legal perspective on human rights and demonstrate that individual agency can make an important contribution to the effective implementation of human rights in the field of migration governance. Behind the black box of the state and local authorities, we find individuals who use human rights—as law, practice and discourse—in local policymaking, in circumstances where invoking human rights is not self-explanatory. Finally, we put forward the notion that reasons such as individual background, motivations, and interactions between individuals influence municipal officials’ engagement with human rights, and we reflect on the conceptual and practical implications that result from this.
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Durmuş, Elif. "How Human Rights Cross-Pollinate and Take Root: Local Governments and Refugees in Turkey." In Myth or Lived Reality. T.M.C. Asser Press, 2021. http://dx.doi.org/10.1007/978-94-6265-447-1_6.

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AbstractThe human rights regime—as law, institutions and practice—has been facing criticism for decades regarding its effectiveness, particularly in terms of unsatisfactory overall implementation and the failure to protect the most vulnerable who do not enjoy the protection of their States: refugees. Turkey is the country hosting the largest refugee population, with around four million at the end of May 2020 (https://www.unhcr.org/tr/wp-content/uploads/sites/14/2020/06/UNHCR-Turkey-Operational-Update-May-2020.pdf). As an administratively centralised country, Turkey’s migration policy is implemented by central government agencies, but this has not proved sufficient to guarantee the human rights of refugees on the ground. Meanwhile, in connection with urbanisation, decentralisation and globalisation, local governments around the world are receiving increasing attention from migration studies, political science, law, sociology and anthropology. In human rights scholarship, the localisation of human rights and the potential role of local governments have been presented as ways to counter the shortcomings in the effectiveness of the human rights regime and discourse. While local governments may have much untapped potential, a thorough analysis of the inequalities between local governments in terms of access to resources and opportunities is essential. The Turkish local governments which form the basis of this research, operate in a context of legal ambiguity concerning their competences and obligations in the area of migration. They also have to deal with large differences when it comes to resources and workload. In practice, therefore, there is extreme divergence amongst municipalities in the extent to which they engage with refugee policies. This chapter seeks to answer the question why and how certain local governments in Turkey come to proactively engage in policy-making that improves the realisation of refugees’ rights. Exploratory grounded field research among Turkish local governments reveals four main factors that enable and facilitate the engagement of local governments in refugee policies: (1) the capacity of and institutionalisation in local governments; (2) the dissemination of practices and norms surrounding good local migration and rights-based governance through networks; (3) the availability of cooperation and coordination with other actors in the field, and (4) political will. Collectively, these factors illustrate how a new norm—the norm that local governments can and ought to engage in policy-making improving the rights of refugees—is cross-pollinating and taking root among Turkish local governments. This understanding will provide valuable insights into how norms are developed, travel and are institutionalised within social and institutional networks, and how differences in access, capacity, political and cooperative opportunities may facilitate and obscure the path to policies improving human rights on the ground.
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Ciobanu, Dragoș. "Collaborative Student Translation Projects." In Advances in Linguistics and Communication Studies. IGI Global, 2018. http://dx.doi.org/10.4018/978-1-5225-4154-7.ch009.

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This chapter describes how Project-based learning (PBL) is a training method proven to make learning experiences memorable, motivating and meaningful. This article summarises the responses given between 2015 and 2016 by members of the European Masters in Translation (EMT) Network to a detailed questionnaire on the way in which collaborative translation projects are conducted throughout the network. These responses have also been enriched with the outcomes of follow-up discussions led by the EMT Working Group on Collaborative Learning and e-Learning, as well as 1.5 million words' worth of collaborative localisation projects organised in the University of Leeds Centre for Translation Studies between 2012 and 2017. The result is an inventory of approaches and best-practice tips organised into five major sections covering the main aspects associated with designing, implementing and promoting collaborative student projects in translation and localisation.
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Van Haeperen, Françoise. "Ostia. Lieu de culte (ara) de la Concorde (localisation incertaine)." In Fana, templa, delubra. Corpus dei luoghi di culto dell'Italia antica (FTD) - 6. Collège de France, 2019. http://dx.doi.org/10.4000/books.cdf.6426.

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Powell, Martin. "Coalition health policy: a game of two halves or the final whistle for the NHS?" In Social Policy Review 28. Policy Press, 2016. http://dx.doi.org/10.1332/policypress/9781447331797.003.0002.

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This chapter contains an analysis of the development of the NHS under the Coalition Government. While some argue that under the Coalition Government the UK approaches the end of the NHS, the analysis shows that the reforms initiated by the Coalition Government have diverging directions and diverging ideological foundations. Whereas in the first part of the Coalition Government’s rule merely competition, privatization and marketization dominated the debate, the second part stills carries the heritages of the neo-liberal paradigm but also introduces other measures to improve the performance of the NHS and guarantee its financial sustainability: prevention, integration and localisation. But the question is if these initiatives are strong enough to guarantee a bright future for the NHS.
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Olivares, P. Cavestany, D. Herrero-Pérez, J. J. Alcaraz Jiménez, and H. Martínez Barberá. "An Embedded Vision System for RoboCup." In Robotic Vision. IGI Global, 2013. http://dx.doi.org/10.4018/978-1-4666-2672-0.ch018.

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In this chapter, the authors describe their vision system used in the Standard Platform League (SPL), one of the official leagues in RoboCup competition. The characteristics of SPL are very demanding, as all the processing must be done on board, and the changeable environment requires powerful methods for extracting information and robust filters. The purpose is to show a vision system that meets these goals. The chapter describes the architecture of the authors’ system as well as the flowchart of the image process, which is designed in such a manner that allows a rapid and reliable calibration. The authors deal with field features detection by finding intersections between field lines at frame rate, using a fuzzy-Markov localisation technique. Also, the methods implemented to recognise the ball and goals are explained.
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Conference papers on the topic "Localisation de ARN"

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Williams, M. "Localisation and wordprocessing." In IEE Colloquium Speech and Language Engineering - State of the Art. IEE, 1998. http://dx.doi.org/10.1049/ic:19980964.

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Georgiou, Evangelos, Jian S. Dai, and Michael Luck. "The KCLBOT: A Double Compass Self-Localizing Maneuverable Mobile Robot." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-47753.

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The key to autonomous mobile-robot navigation is effective path planning and accurate self-localisation. The lack of self-localisation or inaccurate self-localisation makes any nonholonomic autonomous mobile robot blind in a navigation environment and will deter the robot’s ability to complete path following. In the last several years, many different systems have been considered for self-localisation, from using visual odometry to using a satellite triangulation method, better known as a global position system or GPS. All of these have benefits and detriments, the solution proposed here endeavors to offer more benefits than detriments, utilizing a novel method for self-localisation, employing a dual bearing finder digital compass configuration to resolve the relative location of an autonomous nonholonomic wheeled mobile robot. To facilitate the novel hybrid method, the utilization of the mobile robot’s multiple sensors, dual wheel quadrature shaft encoders and the digital compasses are required. To support the hardware requirements of the novel localisation methodology, the cutting edge technology of a 200 MHz 32-bit ARM 9 processor on a GHI ChipworkX module are employed. The software architecture is based on the Microsoft .NET Micro Framework 4.1 using C# and the Windows Presentation Foundation (WPF). Without the inputs from the dual compass configuration it would not be possible to solve the relative position of the mobile robot analytical. Without the dual compass configuration only a numeric solution is possible, which decelerates the localisation process. The mobile robot’s digital compasses are marked with unnatural markers, for faster identification by an overhead camera. Using the overhead camera tracking results and comparing the telemetry collected by the mobile robot, using the analytical equations, the validation of this method is proven. The most fundamental part of implementing a successful maneuverable nonholonomic mobile robot is accurate self-localisation telemetry. The biggest concern about using a self-localisation technique is the amount of computation it will require to complete the task. Ideally, having an analytical solution to position offers the benefit of a single solution, where the numeric solution has many solutions and requires more time and computation to derive the solution. The benefit of the dual compass configuration is that it offers an analytical solution to the hybrid model that utilizes quadrature shaft encoders and digital compasses. This methodology evidently presents a novel approach where visual odometry is not possible.
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Lu, Tien-Fu. "Indoor odour source localisation using robot: Are there advantageous initial locations?" In 2011 IEEE International Conference on Robotics and Biomimetics (ROBIO). IEEE, 2011. http://dx.doi.org/10.1109/robio.2011.6181316.

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Busteed, S., MW Bennett, M. Stone, et al. "THU0099 The localisation of flice inhibitory protein (flip) in rheumatoid synovium." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.976.

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Rabla, Michael, Etienne Tisserand, Patrick Schweitzer, and Jinmi Lezama. "Arc Fault Analysis and Localisation by Cross-Correlation in 270 V DC." In 2013 IEEE 59th Holm Conference on Electrical Contacts (Holm 2013). IEEE, 2013. http://dx.doi.org/10.1109/holm.2013.6651400.

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Barde, Amit, Gun Lee, William S. Helton, and Mark Billinghurst. "Binaural Spatialisation Over a Bone Conduction Headset: Elevation Perception." In The 22nd International Conference on Auditory Display. The International Community for Auditory Display, 2016. http://dx.doi.org/10.21785/icad2016.013.

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Preliminary results from an on-going experiment exploring the localisation accuracy of a binaurally processed source displayed via a bone conduction headset are described. These results appear to point to decreased localisation accuracy in the horizontal plane when the vertical component is introduced. There also appears to be a significant compression in the area directly in front of the observer ± 15° in elevation from 0°. This suggests that participants tended to localise stimuli presented at elevations greater than and less than ± 30° within a 30° ‘window’ extending 15° vertically either above or below the horizontal plane defined by the 0° azimuth. The results gathered until now suggest that binaural spatialisation over a bone conduction headset can also reproduce the perception of an elevated source to an acceptable degree of accuracy.
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Miro, Jaime Valls, Fredy Munoz, and Freyja Ivorie Miguel. "An Arc-Shaped Rotating Magnet Solution for 3D Localisation of a Drug Delivery Capsule Robot." In 2020 IEEE/ASME International Conference on Advanced Intelligent Mechatronics (AIM). IEEE, 2020. http://dx.doi.org/10.1109/aim43001.2020.9158966.

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Siller, Henri A. "Localisation of Sound Sources on Aircraft in Flight." In ASME 2012 Noise Control and Acoustics Division Conference at InterNoise 2012. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/ncad2012-0575.

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This paper presents beamforming techniques for source localization on aicraft in flight with a focus on the development at DLR in Germany. Fly-over tests with phased arrays are the only way to localize and analyze the different aerodynamic and engine sources of aircraft in flight. Many of these sources cannot be simulated numerically or in wind-tunnel tests because they they are either unknown or they cannot be resolved properly in model scale. The localization of sound sources on aircraft in flight is performed using large microphone arrays. For the data analysis, the source signals at emission time are reconstructed from the Doppler-shifted microphone data using the measured flight trajectory. Standard beamforming techniques in the frequency domain cannot be applied due transitory nature of the signals, so the data is usually analyzed using a classical beamforming algorithm in the time domain. The spatial resolution and the dynamic range of the source maps can be improved by calculating a deconvolution of the sound source maps with the point spread function of the microphone array. This compensates the imaging properties of the microphone array by eliminating side lobes and aliases. While classical beamfoming yields results that are more qualitative by nature, the deconvolution results can be used to integrate the acoustic power over the different source regions in order to obtain the powers of each source. ranking of the sources. These results can be used to rank the sources, for acoustic trouble shooting, and to assess the potential of noise abatement methods.
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Denny, W., B. O’Connell, J. Milroy, and M. Walsh. "Drug Eluting Stents: Modelling the Physics of Mass Transport in the Arterial Wall." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19107.

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Coronary artery disease (CAD), which results in inadequate blood flow to the heart, is responsible for 1 in every 4.8 deaths in the USA (Lloyd-Jones et al., 2009). Currently, there are 16.5 million patients with stable angina and 500,000 new diagnoses annually (Gibbons et al., 2003). CAD has been linked with atherosclerosis since the early 20th century (McMahan et al., 2008) and refers to the localisation of the disease in the coronary arteries. Atherosclerosis is a degenerative disease that affects not only the coronary arteries, but also the carotid and other peripheral arteries in the body.
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Parloo, Eli, Steve Vanlanduit, Peter Verboven, and Patrick Guillaume. "Modal Analysis Based Structural Damage Localisation Under Varying Operating Conditions." In ASME 7th Biennial Conference on Engineering Systems Design and Analysis. ASMEDC, 2004. http://dx.doi.org/10.1115/esda2004-58188.

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A variation in the operating condition of a structural health monitored system can have a very bad influence on the performance of modal based techniques. The modal parameter changes caused by, for instance, uncontrolled temperature fluctuations can easily mask small changes in these parameters that are caused by structural defects. In this contribution, a method is proposed for compensating the effect of unknown global variations in the natural frequencies of a test structure: e.g. uniform coatings and/or uniform (environmental) temperature changes. Unlike other methods, the compensated results are used for localising as well as detecting structural damage.
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