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Journal articles on the topic 'Locally advanced carcinoma breast'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Jain, Sanjay, Guka Priyan K. M., and M. C. Songara. "Clinico-pathological study of locally advanced breast cancer and their hormone receptor analysis." International Surgery Journal 7, no. 9 (2020): 2951. http://dx.doi.org/10.18203/2349-2902.isj20203774.

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Background: Breast carcinoma is one of the most common malignant tumor of women. Determination of estrogen receptors (ER) and progesterone receptors (PR) status, prior to therapeutic intervention has become standard practice. Survival and response to hormone therapy are most favorable among women who are receptor positive. The aim of this study is to assess the hormone receptor status in locally advanced breast carcinomas and correlate this reactivity pattern with tumor stage, clinical stage and lymph node metastasis. Objective of the study was to co-relate the locally advanced breast cancer a

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2

Lopez, Marvin J., Dorothy P. Andriole, William G. Kraybill, and Ali Khojasteh. "Multimodal therapy in locally advanced breast carcinoma." American Journal of Surgery 160, no. 6 (1990): 669–75. http://dx.doi.org/10.1016/s0002-9610(05)80772-x.

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3

Yarom, I., M. Steiner, R. Borovik, and I. Rabinovich. "Neoadjuvant chemotherapy in locally advanced breast carcinoma." European Journal of Cancer 29 (January 1993): S79. http://dx.doi.org/10.1016/0959-8049(93)91034-i.

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4

Hobar, Paul Creighton. "Multimodality Treatment of Locally Advanced Breast Carcinoma." Archives of Surgery 123, no. 8 (1988): 951. http://dx.doi.org/10.1001/archsurg.1988.01400320037006.

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5

Singhal, Juhi, Sandeep Gupta, and Shivam Sharma. "Role of Breast Conservation Surgery in Patients with Locally Advanced Breast Carcinoma after Neoadjuvant Chemoradiotherapy." International Journal of Science and Research (IJSR) 11, no. 9 (2022): 609–11. http://dx.doi.org/10.21275/mr22912220634.

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6

Anderson, William F., Kenneth C. Chu, and Shine Chang. "Inflammatory Breast Carcinoma and Noninflammatory Locally Advanced Breast Carcinoma: Distinct Clinicopathologic Entities?" Journal of Clinical Oncology 21, no. 12 (2003): 2254–59. http://dx.doi.org/10.1200/jco.2003.07.082.

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Purpose: Inflammatory breast carcinoma (IBC) and noninflammatory locally advanced breast carcinoma (LABC) are both associated with poor prognosis; however, whether they are distinct clinicopathologic entities remains controversial. Materials and Methods: To determine whether IBC and LABC were different, we compared tumor characteristics, prognosis, and age-specific incidence rate patterns in the Surveillance, Epidemiology, and End-Results program. An age of 50 years served as a surrogate marker for menopause. Results: Younger age at diagnosis, poorer tumor grade, and negative estrogen receptor

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7

Girardi, V., G. Carbognin, L. Camera, et al. "Inflammatory breast carcinoma and locally advanced breast carcinoma: characterisation with MR imaging." La radiologia medica 116, no. 1 (2010): 71–83. http://dx.doi.org/10.1007/s11547-010-0590-4.

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8

Muzikravic, Ljubomir, Dragutin Donat, Jasna Pesic, and Jasna Trifunovic. "Maintaining treatment of locally advanced breast cancer." Archive of Oncology 11, no. 3 (2003): 145–47. http://dx.doi.org/10.2298/aoo0303145m.

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Locally advanced breast cancer is a specific clinic entity, comprising various degrees of breast cancer local and regional extension. This term is applied to nonmetastatic large primary tumors (including inflammatory breast carcinoma), with or without extensive regional lymph node involvement, with a rapid or slow evolution, and usually with poor prognosis. This clinical presentation of mammary carcinoma is common in developing countries (30% to 60%), but also with a remarkable incidence in developed countries (10% to 20%). During many decades patients were treated with radical surgery or radi

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9

Vieira, René Aloisio da Costa, Silvia Maria Prioli de Souza Sabino, Gustavo Zucca Matthes, Anapaula Hidemi Uema Watanabe, and Lucas Faria Abrahao-Machado. "Giant sclerosing papilloma mimicking locally advanced breast carcinoma." Revista da Associação Médica Brasileira 60, no. 6 (2014): 518–19. http://dx.doi.org/10.1590/1806-9282.60.06.007.

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10

Jenna, Prabhakar, and Sushma Jagadev. "A STUDY OF LOCALLY ADVANCED CARCINOMA OF BREAST." Journal of Evidence Based Medicine and Healthcare 4, no. 68 (2017): 4093–96. http://dx.doi.org/10.18410/jebmh/2017/815.

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11

Gedam, Manik C., Keval Shukla, and Leena Y. Ingale. "Clinical presentation and management of locally advanced breast carcinoma." International Surgery Journal 5, no. 11 (2018): 3690. http://dx.doi.org/10.18203/2349-2902.isj20184646.

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Background: Locally advanced breast cancer (LABC) encompasses a heterogeneous collection of breast neoplasia with widely different clinical and biological characteristics. Multidisciplinary therapy has become the treatment of choice for these patients. The present study was undertaken to study the clinical presentation and effects of various modes of management of LABC.Methods: Total 45 patients presented with stage III and inflammatory carcinoma of breast were included in the study and treated with neoadjuvant chemotherapy, followed by surgery and radiotherapy. Clinical and pathological respo

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12

Ibrahim, Alaa M., Mahmoud M. Said, Amany M. Hilal, Amina M. Medhat, and Ibrahim M. Abd Elsalam. "Candidate circulating microRNAs as potential diagnostic and predictive biomarkers for the monitoring of locally advanced breast cancer patients." Tumor Biology 42, no. 10 (2020): 101042832096381. http://dx.doi.org/10.1177/1010428320963811.

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This study aimed at investigating the expression of candidate microRNAs (miRs), at initial diagnosis, during neoadjuvant chemotherapy, and after the tumor resection in locally advanced breast cancer patients. Plasma samples were collected from locally advanced breast cancer patients (n = 30) and healthy subjects (n = 20) for the detection of candidate miRs’ expression using the real-time quantitative polymerase chain reaction. At initial locally advanced breast cancer diagnosis, the expression of miR-21, miR-181a, and miR-10b was significantly increased, whereas that of miR-145 and let-7a was

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13

Perez, Carlos A., Joseph N. Fields, Paula M. Fracasso, et al. "Management of locally advanced carcinoma of the breast: II. Inflammatory carcinoma." Cancer 74, S1 (1994): 466–76. http://dx.doi.org/10.1002/cncr.2820741336.

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14

Ambore, Dr Vinaya K. "A Study on Role of Neo adjuvant Chemotherapy in Locally Advanced Carcinoma of Breast." Journal of Medical Science And clinical Research 05, no. 04 (2017): 20620–23. http://dx.doi.org/10.18535/jmscr/v5i4.144.

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15

Borkar, Mrinalini, Quraishi A M, and Junaid Sheikh. "A CLINICAL STUDY OF LOCALLY ADVANCED CARCINOMA OF BREAST." Journal of Evidence Based Medicine and Healthcare 2, no. 22 (2015): 3301–14. http://dx.doi.org/10.18410/jebmh/2015/480.

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16

P, Nagpal, Shankar A, YadavB S, Singh R, D. Divya, and Ghoshal S. "METASTATIC BEHAVIOUR OF SUBTYPES IN LOCALLY ADVANCED CARCINOMA BREAST." International Journal of Advanced Research 5, no. 7 (2017): 2549–53. http://dx.doi.org/10.21474/ijar01/4996.

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17

Biesta, J., and H. Struikmans. "High-dose radiotherapy treatment for locally advanced breast carcinoma." European Journal of Cancer Supplements 6, no. 7 (2008): 137. http://dx.doi.org/10.1016/s1359-6349(08)70615-3.

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18

Toonkel, Leonard M., Ivor Fix, Lawrence H. Jacobson, Norman Bamberg, and Carl B. Wallach. "Locally advanced breast carcinoma: results with combined regional therapy." International Journal of Radiation Oncology*Biology*Physics 12, no. 9 (1986): 1583–87. http://dx.doi.org/10.1016/0360-3016(86)90281-6.

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19

Sonvane, Shwetal Ravindrabhai, Mukesh Pancholi, and Akhil Sharma. "A clinical study of outcome of neoadjuvant chemotherapy in 30 cases of locally advanced breast carcinoma." International Surgery Journal 6, no. 12 (2019): 4383. http://dx.doi.org/10.18203/2349-2902.isj20195398.

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Background: Locally advanced breast cancer presents with a difficult management problem. It remains a challenge to achieve local and distant control of locally advanced breast cancer. Over the last decade preoperative/ neoadjuvant chemotherapy has emerged as the standard of care for these patients. Successful reduction in the size of the tumor is associated with increased rate of operability. The objective of this study is to observe the response of neoadjuvant chemotherapy in locally advanced breast carcinoma in form of outcome and complications. The outcome is measured as down staging or dow

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20

Mardynsky, Yury S., Igor A. Gulidov, Gamzat G. Aminov, Yury A. Ragulin, Igor I. Kotuchov, and Konstantin B. Gordon. "Reactor Neutrons in Multimodality Treatment of Locally Advanced Breast Carcinoma." Advanced Materials Research 1084 (January 2015): 464–66. http://dx.doi.org/10.4028/www.scientific.net/amr.1084.464.

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We present long-term treatment outcomes of 201 patients with breast carcinoma who received a radical course of radiation therapy as a component of multimodality treatment. Ninety five of them received mixed photon-neutron therapy (the study group), and 106 patients received photon therapy (control group). All patients had stage III breast cancer. The presented data on the mixed photon-neutron therapy prove feasibility of achievement of high efficiency of treatment and satisfactory level of quality of patient’s life. This approach opens additional opportunities for expansion of a scope of neutr

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21

Gupta, Vishnu, Revati Gupta, Rajesh Aggrawal, and Ajit Chhatre. "Clinicopathological response and breast conservation in locally advanced breast cancer cases treated with neoadjuvant chemotherapy." International Journal of Medicine and Medical Research 10, no. 2 (2024): 16–25. https://doi.org/10.61751/ijmmr/2.2024.16.

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Neoadjuvant chemotherapy is crucial for enhancing surgical outcomes and enabling breast conservation in locally advanced breast adenocarcinoma, which is often inoperable. This prospective cohort study aimed to evaluate the clinic-pathological response and breast conservation rates in patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy. The patients were administered chemotherapy according to a standard protocol and were followed until their surgical outcome. Out of a total of 90 patients with locally advanced breast cancer, 78 were eligible for neoadjuvant therapy.

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22

Mehmood, Tahir, Muhammad Ali, Kamran Saeed, et al. "Taxanes-based neoadjuvant chemotherapy in advanced nonmetastatic breast cancer." Journal of Clinical Oncology 31, no. 15_suppl (2013): e12033-e12033. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e12033.

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e12033 Background: Pakistan has the highest rate of breast cancer for any South Asian population and majority of the patients present with locally advanced or metastatic disease. We report on response and survival of primary locally advanced non-metastatic breast cancer in women treated with neoadjuvant Adriamycin/Taxanes (AT) based regimens at our institute. Methods: Between 1995 to 2009 the hospital information system identified 517 women with pathologically confirmed locally advanced breast cancer. All patients received neoadjuvant chemotherapy with AT based regimen followed by surgery. Med

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23

OURA, Shoji, Takeo SAKURAI, Goro YOSHIMURA, Takeshi TAMAKI, Teiji UMEMURA, and Yozo KOKAWA. "A CASE OF LOCALLY ADVANCED BREAST CARCINOMA WITH MEIGS' SYNDROME." Journal of the Japanese Practical Surgeon Society 58, no. 5 (1997): 981–84. http://dx.doi.org/10.3919/ringe1963.58.981.

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24

Xu, Jian-Ming, San-Tai Song, Zhong-Ming Tang, et al. "Neoadjuvant Chemotherapy in Inoperable, Locally Advanced, and Inflammatory Breast Carcinoma." American Journal of Clinical Oncology 24, no. 3 (2001): 259–63. http://dx.doi.org/10.1097/00000421-200106000-00010.

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25

Nagpal, P., A. Shanker, B. S. Yadav, S. Ghoshal, R. Singh, and D. Dahiya. "94P Metastatic behavior of subtypes in locally advanced breast carcinoma." Annals of Oncology 26 (December 2015): ix16. http://dx.doi.org/10.1093/annonc/mdv519.43.

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26

Kaushal, M., S. Shukla, R. K. Mathur, D. Kaushal, R. S. Gupta, and M. C. Songara. "Complications of surgery in management of locally advanced breast carcinoma." European Journal of Cancer Supplements 6, no. 7 (2008): 137. http://dx.doi.org/10.1016/s1359-6349(08)70617-7.

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27

Perez, Carlos A., Mary L. Graham, Marie E. Taylor, et al. "Management of locally advanced carcinoma of the breast I. Noninflammatory." Cancer 74, S1 (1994): 453–65. http://dx.doi.org/10.1002/cncr.2820741335.

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28

Monge, O. R., H. Lyng, E. K. Rofstad, et al. "Phase II-Study of thermoradiotherapy for locally advanced breast carcinoma." International Journal of Radiation Oncology*Biology*Physics 19 (January 1990): 263. http://dx.doi.org/10.1016/0360-3016(90)90915-7.

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29

Hayashi, Masanori, Shoji Oura, and Haruka Nishiguchi. "Multidisciplinary Treatment for Locally Advanced Mucinous Breast Cancer." Case Reports in Oncology 17, no. 1 (2024): 837–42. http://dx.doi.org/10.1159/000539717.

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Background: Due to its indolent biology and high estrogen receptor positivity of mucinous breast cancer, vast majority of locally advanced mucinous breast cancer (LABC) are treated with first-line endocrine therapy. Case Presentation: A 50-year-old woman was referred to our hospital for the treatment of her huge breast tumor. Computed tomography showed an oval solid tumor, 17 cm in size, and lymph node swelling in both the axilla and parasternum. Pathological study of the core needle biopsy specimen showed the tumor to be luminal mucinous carcinoma. After the failure of endocrine therapy aimin

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30

Liu, Chung-Tang, and Keri Lanier. "Abstract P1-10-06: Carcinoma en Cuirasse Secondary to Locally Advanced Breast Carcinoma: a case report." Cancer Research 83, no. 5_Supplement (2023): P1–10–06—P1–10–06. http://dx.doi.org/10.1158/1538-7445.sabcs22-p1-10-06.

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Abstract Introduction & Objective This report highlights an unusual presentation of skin metastasis of inflammatory breast cancer that resembles a rare condition called Carcinoma en Cuirasse (CeC). CeC was first described by anatomist Alfred Velpeau in 1838 when he observed how the coalescing nodules and diffuse sclerodermoid induration found on the chest and abdomen in CeC resembled the medieval steel breastplate or a cuirasse. Case Presentation A 62-year-old female presented to the emergency department for evaluation of a palpable left breast mass and concurrent skin lesions for the past

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31

Castañeda, Carlos, Raymundo Flores, Katerin Ingrid Rojas, et al. "Mammographic findings in locally advanced breast carcinoma treated with neoadjuvant chemotherapy." Journal of Clinical Oncology 31, no. 15_suppl (2013): e12538-e12538. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e12538.

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e12538 Background: Breast Cancer (BC) is a heterogeneous disease. Mammograpy images of BC has been associated with tumor features. We evaluated relationship between radiologic features of pre-neoadjuvant chemotherapy (NAC) lesions and clinico pathological tumor features. Methods: We evaluated mammography films and clinicopathological information of BC patient who received NAC followed by tumor resection at Instituto Nacional de Enfermedades Neoplásicas from 2000 to 2011. Results: 495 BC cases were selected. Most cases were staged in clinical Tumor size stage 4 (48.2%) and node stage 1 (58.7%);

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32

Yeh, Karen A., A. P. Jillella, and J. P. Wei. "Surgery for T4 Breast Carcinoma: Implications for Local Control." American Surgeon 66, no. 3 (2000): 250–55. http://dx.doi.org/10.1177/000313480006600305.

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Despite increasing public awareness and widespread availability of mammography, many patients will present with locally advanced breast cancers. The role of surgery remains controversial. Between 1993 and 1998, 47 of 393 (11.9%) breast cancer patients presented with T4 (inflammatory or locally advanced) carcinoma. We reviewed multimodality management, clinical response to neoadjuvant therapy, perioperative course and complications, and local control. Forty-six women and one man were diagnosed with clinical T4 breast cancer. There were 24 white and 23 African-American patients. Mean age at pres

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33

Singletary, S. Eva, Marsha D. McNeese, and Gabriel N. Hortobagyi. "Feasibility of breast-conservation surgery after induction chemotherapy for locally advanced breast carcinoma." Cancer 69, no. 11 (1992): 2849–52. http://dx.doi.org/10.1002/1097-0142(19920601)69:11<2849::aid-cncr2820691134>3.0.co;2-p.

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34

Schwartz, Gordon F., Christine A. Birchansky, Lydia T. Komarnicky, et al. "Induction chemotherapy followed by breast conservation for locally advanced carcinoma of the breast." Cancer 73, no. 2 (1994): 362–69. http://dx.doi.org/10.1002/1097-0142(19940115)73:2<362::aid-cncr2820730221>3.0.co;2-l.

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35

Dr.Geetika, P. "Role of Ultrasound and Doppler Indices in Assessment of Tumor Response to Neoadjuvant Chemotherapy in Breast Malignancy." International Journal of Medical and Pharmaceutical Research 4, no. 5 (2023): 15–29. https://doi.org/10.5281/zenodo.8346408.

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<strong>Background:</strong>Neoadjuvant chemotherapy (NAC) is frequently employed in the treatment of early and locally advanced breast carcinomas. Evaluating the response of the tumor to such treatment is crucial for deciding subsequent therapeutic steps. Ultrasound and Doppler indices present as a non-invasive and cost-effective approach for this assessment. This study aims to elucidate the role of ultrasound and color doppler indices in assessing the response of breast malignancies to NAC.   <strong>Methods:</strong>Patients diagnosed with early breast carcinoma and locally advanced br

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36

Parvathaneni, Nagendra, Susmitha P., Ishfaq Gilkar, et al. "Isolated advanced chest wall recurrence with a rectified reconstruction." International Surgery Journal 11, no. 12 (2024): 2168–70. http://dx.doi.org/10.18203/2349-2902.isj20243569.

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In developed nations, breast cancer stands as the primary cause of cancer-related death among females. Local recurrence is often considered an initial sign of treatment ineffectiveness, occurring on the chest wall, axilla, or ipsilateral breast post Breast-Conserving Surgery (BCS). Local recurrence is observed in approximately 30% of patients with locally advanced breast cancer. A 58-year-old postmenopausal woman, who is a known case of triple negative breast cancer presented to us with an ulcerative lesion over left chest wall. In the past, she underwent neoadjuvant chemotherapy followed by l

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37

Zapletal, Ondřej, Jan Žatecký, Lucie Gabrielová, et al. "Axillary Overtreatment in Patients with Breast Cancer After Neoadjuvant Chemotherapy in the Current Era of Targeted Axillary Dissection." Cancers 17, no. 2 (2025): 178. https://doi.org/10.3390/cancers17020178.

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Background: In the current era of targeted axillary dissection (TAD), there are still cases where axillary lymph node dissection (ALND) is indicated, but histopathological examination confirms the regression of nodal metastases (ypN0). In this situation, ALND may represent undesirable overtreatment. Methods: A retrospective study at the Comprehensive Cancer Centre was conducted based on a prospectively maintained database. Patients who underwent surgery after neoadjuvant chemotherapy (NAC) between 2020 and 2023 were selected, specifically those for whom ALND was directly indicated after NAC. S

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38

Atchison, Linsey, Thomas Hardy, Tara Mancl, Brian Patrick Quaranta, and Ankit Madan. "Locally Advanced Primary Small Cell Carcinoma of the Breast: A Case Report and Review of Current Evidence." Case Reports in Oncology 14, no. 2 (2021): 761–66. http://dx.doi.org/10.1159/000515505.

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Small-cell breast carcinoma (SCBC) is a very rare type of aggressive breast cancer constituting less than 1% of all breast cancers. The WHO classification categorizes this tumor as small-cell neuroendocrine carcinoma, and its prognosis is usually worse as compared to invasive breast cancers. We report a 64-year-old Caucasian female who presented with a large fungating left breast mass. Biopsy of the mass revealed small-cell carcinoma of the breast, negative for all 3 receptors (estrogen, progesterone, and Her2/neu). Imaging studies were negative for distant metastasis. She was subsequently tre

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39

Leung, Ting Kai, Pai Jung Huang, Lei Ming Sun, et al. "Silicone Breast Implant with Intracapsular Rupture Coexisting with Locally Advanced Carcinoma." Breast Journal 18, no. 1 (2011): 76–77. http://dx.doi.org/10.1111/j.1524-4741.2011.01187.x.

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40

Sousa, C., L. Pinto, M. Cruz, et al. "EP-1327 Impact of neoadjuvant radiotherapy in locally advanced breast carcinoma." Radiotherapy and Oncology 133 (April 2019): S727. http://dx.doi.org/10.1016/s0167-8140(19)31747-5.

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41

Cance, William G., Lisa A. Carey, Benjamin F. Calvo, et al. "Long-Term Outcome of Neoadjuvant Therapy for Locally Advanced Breast Carcinoma." Annals of Surgery 236, no. 3 (2002): 295–303. http://dx.doi.org/10.1097/00000658-200209000-00006.

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42

Nakagawa, Tomoe, Koichi Sato, Minoru Moriwaki, et al. "Successful Endocrine Therapy for Locally Advanced Mucinous Carcinoma of the Breast." Breast Journal 18, no. 6 (2012): 632–33. http://dx.doi.org/10.1111/tbj.12031.

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43

McLean, A. D., J. C. Doughty, A. W. Reid, D. H. McCarter, E. Kane, and C. S. McArdle. "Pneumonitis complicating selective intra-arterial chemotherapy for locally advanced breast carcinoma." Postgraduate Medical Journal 72, no. 844 (1996): 117–18. http://dx.doi.org/10.1136/pgmj.72.844.117.

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44

Thilakaratna, W. M. S. Buddhika, M. H. Renos, K. Janani, S. Sakashan, and E. A. D. N. Jayasinghe. "Comparison of Breast Cancer Management and Outcomes in a Single Cancer Surgical Unit in Teaching Hospital- Batticaloa, Sri Lanka: A Retrospective Analysis of Two Time Periods (2016-2018 vs. 2022-2024)." Batticaloa Medical Journal 18, no. 2 (2024): 26–32. https://doi.org/10.4038/bmj.v18i2.49.

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Objective: To compare the clinical characteristics, management approaches, and surgical outcomes of breast cancer patients treated at this institution during two distinct time periods (2016–2018 and 2022–2024).Methods: A retrospective review of breast cancer cases was conducted. A total of 93 female patients were included in each period, categorized into early invasive breast carcinoma (EIBC), locally advanced breast carcinoma (LABC), and metastatic breast carcinoma (MBC). Treatment modalities, including neoadjuvant chemotherapy, breast conservation, sentinel lymph node biopsy, and breast reco

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45

Vania Idelia Winantyo, Vidi Vianney Chrisana Magrit Tanggo, and Iskandar Ali. "Association of neutrophil-lymphocyte ratio (NLR) with the anthracycline-based neoadjuvant chemotherapy (NAC) clinical response in locally advanced breast cancer (LABC) in young women." Bali Medical Journal 11, no. 2 (2022): 602–8. http://dx.doi.org/10.15562/bmj.v11i2.3564.

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Background: Breast cancer in young women is one of the leading causes of cancer death in young women worldwide, including in Indonesia. Most patients come to the hospital at the advanced stage. Neoadjuvant chemotherapy (NAC) is the standard treatment for locally advanced breast cancer. However, half of breast cancer patients had a negative response to therapy.  Methods: A retrospective cohort, analytic observational study to determine the association between NLR and anthracycline-based NAC clinical response in locally advanced young age breast cancer in Dr. Soetomo General Hospital, Sura

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46

Rakib, Shaikh Adnan, Sayeed Bin Sharif, Morsalin Rahman, Farhana Islam, and Kazi Shaila Najnin. "Surgical Outcome after Downstaging in Locally Advanced Breast Carcinoma-A Clinical Study of 50 Cases." KYAMC Journal 13, no. 4 (2023): 229–33. http://dx.doi.org/10.3329/kyamcj.v13i4.63191.

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Background: The number of deaths related to breast cancer is increasing at an alarming pace worldwide. In Bangladesh, the incidence rate of breast cancer was about 22.5 per 100000 females. Almost everyone has a palpable lump, and 40% of them have locally advanced breast cancer. The typical treatment for patients with LABC is neoadjuvant chemotherapy followed by surgery. Materials and Methods: From January 2018 to December 2022, 50 newly diagnosed locally advanced breast cancer (LABC) patients were enrolled in this prospective study at the Bangladesh Medical College Hospital, Dhaka; to assess t

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47

Rahmat, K., CH Yip, NR D′Cruz, KJ Jayaprasagam, KT Wong, and F. Moosa. "A rare case of Hodgkin′s breast lymphoma masquerading as locally advanced breast carcinoma." Indian Journal of Cancer 48, no. 1 (2011): 118. http://dx.doi.org/10.4103/0019-509x.76634.

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48

Birchansky, Christine A., Gordon F. Schwartz, Lydia T. Komarnicky, et al. "Induction (neoadjuvant) chemotherapy and breast conserving treatment for locally advanced carcinoma of the breast." International Journal of Radiation Oncology*Biology*Physics 24 (January 1992): 300. http://dx.doi.org/10.1016/0360-3016(92)90426-i.

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49

Zee, B. C., C. Wong, T. Kuhn, et al. "Detection of circulating tumor cells (CTCs) in patients with hepatocellular carcinoma (HCC)." Journal of Clinical Oncology 25, no. 18_suppl (2007): 15037. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.15037.

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15037 Background: Allard et al. (2004) has established the accuracy, sensitivity, reliability and linearity of circulating tumor cells (CTCs) detection using the CellSearch System. 57% prostate cancers, 37% breast cancers, 37% ovarian cancers, 30% colorectal cancers, and 20% lung cancers specimens had >= 2 CTCs per 7.5 mL of blood. Only 0.3% healthy non-malignant disease subjects had >= 2 CTCs per 7.5 mL of blood. Cristofanilli et al.(2004,2005) have shown that CTCs at baseline and first follow-up were a significant prognostic factor for survival in metastatic breast cancer patients. How

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Majd, H., K. Maadin, M. T. Saoudi, et al. "ENDOMETRIAL METASTASIS OF BREAST CANCER: A CASE REPORT AND REVIEW OF THE LITERATURE." International Journal of Advanced Research 13, no. 02 (2025): 422–26. https://doi.org/10.21474/ijar01/20394.

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Abstract:

Endometrial metastasis of breast cancer is an exceptionally rare occurrence, with limited cases reported in the literature. While breast cancer commonly metastasizes to bones, lungs, liver, and brain, endometrial involvement remains unusual and diagnostically challenging. This case report describes a 48-year-old female with a significant family history of breast cancer, presenting with locally advanced left breast carcinoma and widespread metastases, including brain, bone, and endometrial involvement. Initial imaging and histopathology suggested a primary endometrial tumor, but immunohistochem

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